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https://www.readbyqxmd.com/read/28319203/relationship-between-low-tube-voltage-70-kv-and-the-iodine-delivery-rate-idr-in-ct-angiography-an-experimental-in-vivo-study
#1
Michael M Lell, Ulrike Fleischmann, Hubertus Pietsch, Johannes G Korporaal, Ulrike Haberland, Andreas H Mahnken, Thomas G Flohr, Michael Uder, Gregor Jost
OBJECTIVE: Very short acquisition times and the use of low-kV protocols in CTA demand modifications in the contrast media (CM) injection regimen. The aim of this study was to optimize the use of CM delivery parameters in thoraco-abdominal CTA in a porcine model. MATERIALS AND METHODS: Six pigs (55-68 kg) were examined with a dynamic CTA protocol (454 mm scan length, 2.5 s temporal resolution, 70 s total acquisition time). Four CM injection protocols were applied in a randomized order...
2017: PloS One
https://www.readbyqxmd.com/read/28306544/acute-ischemic-stroke-mimicking-subarachnoid-hemorrhage-after-coronary-angioplasty
#2
Ana Pršić, Tomislav Šipić, Krešimr Štambuk, Hrvoje Budinčević
Use of non-ionic contrast media (CM) in coronary arteriography has been reported to cause transient cortical blindness, confusion, amnesia and very rare focal deficits. We report a 69-year old patient with stabile angina pectoris who underwent coronary angioplasty with stent placement due to in-stent thrombosis of the right coronary artery who developed stroke symptoms with radiological suspicion of subarachnoid hemorrhage. No vascular malformations were detected on CT cerebral angiography. Dual antiplatelet treatment was continued...
March 16, 2017: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/28302075/renal-effects-of-metallothionein-induction-by-zinc-in-vitro-and-in-vivo
#3
Moritz Schanz, Lea Schaaf, Juergen Dippon, Dagmar Biegger, Peter Fritz, Mark Dominik Alscher, Martin Kimmel
BACKGROUND: Metallothionein (MTT) is an endogenous antioxidant that can be induced by both zinc (Zn) and ischemia. In kidneys, increased MTT expression exerts a putative protective role in diabetes and hypoxia. Our goal was to further investigate the behavior of MTT under the influence of Zn and hypoxia in vitro and in vivo. METHODS: MTT expression was measured in vitro in cell cultures of proximal tubular cells (LCC-PK1) by immune-histochemistry and real-time PCR after incubation with increasing concentrations of Zn under hypoxic and non-hypoxic conditions...
March 16, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28299609/ascending-aortic-distensibility-and-target-organ-damage-in-primary-hypertension-without-diabetes
#4
Chong-Fu Jia, Zhao-Qian Wang, Xi-Xia Sun, Zhi-Qiang Yang, Yu-Jie Zou, Yi-Nong Jiang
To investigate the relationship between ascending aortic distensibility (AAD) and hypertensive target organ damage (TOD) and its potential value in prediction. One hundred and sixty seven primary hypertension inpatients who underwent coronary CTA examination were enrolled into our study. Retrospective ECG-triggering scanning mode were applied and the images were reconstructed every 5% phase in the entire R-R interval. Maximum and minimum ascending aortic areas as well as the AAD value were calculated on the interested slice...
March 16, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28291680/epidemiology-of-drug-induced-anaphylaxis-in-a-tertiary-hospital-in-korea
#5
Han-Ki Park, Min-Gyu Kang, Min-Suk Yang, Jae-Woo Jung, Sang-Heon Cho, Hye-Ryun Kang
BACKGROUND: Epidemiology and risk factors of drug-induced anaphylaxis are difficult to estimate due to lack of confirmative diagnosis and under reporting. Here we report the current state of drug-induced anaphylaxis in Korea based on an in-hospital pharmacovigilance database in a tertiary hospital. METHODS: This study is a retrospective analysis of drug-induced anaphylaxis, reported to an in-hospital pharmacovigilance center in Seoul National University Hospital from June 2009 to May 2013...
March 10, 2017: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/28291624/corrigendum-to-contrast-media-use-in-patients-with-chronic-kidney-disease-undergoing-coronary-angiography-a-systematic-review-and-meta-analysis-of-randomized-trials-int-j-cardiol-2017-137-144
#6
Bhavi Pandya, Jean M Chalhoub, Valay Parikh, Sainath Gaddam, Jonathan Spagnola, Suzanne El-Sayegh, Marc Bogin, Ruben Kandov, James Lafferty, Sripal Bangalore
No abstract text is available yet for this article.
March 11, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28280699/contrast-induced-acute-kidney-injury-in-kidney-transplant-recipients-a-systematic-review-and-meta-analysis
#7
Wisit Cheungpasitporn, Charat Thongprayoon, Michael A Mao, Shennen A Mao, Matthew R D'Costa, Wonngarm Kittanamongkolchai, Kianoush B Kashani
AIM: To evaluate the incidence of contrast-induced acute kidney injury (CIAKI) in kidney transplant recipients. METHODS: A literature search was performed using MEDLINE, EMBASE, and the Cochrane Database of Systematic Reviews from the inception of the databases through July 2016. Studies assessing the incidence of CIAKI in kidney transplant recipients were included. We applied a random-effects model to estimate the incidence of CIAKI. RESULTS: Six studies of 431 kidney transplant recipients were included in the analyses to assess the incidence of CIAKI in kidney transplant recipients...
February 24, 2017: World Journal of Transplantation
https://www.readbyqxmd.com/read/28280327/biocompatibility-of-very-small-superparamagnetic-iron-oxide-nanoparticles-in-murine-organotypic-hippocampal-slice-cultures-and-the-role-of-microglia
#8
Martin Pohland, Robert Glumm, Frank Wiekhorst, Jürgen Kiwit, Jana Glumm
Superparamagnetic iron oxide nanoparticles (SPIO) are applied as contrast media for magnetic resonance imaging (MRI) and treatment of neurologic diseases despite the fact that important information concerning their local interactions is still lacking. Due to their small size, SPIO have great potential for magnetically labeling different cell populations, facilitating their MRI tracking in vivo. Before SPIO are applied, however, their effect on cell viability and tissue homoeostasis should be studied thoroughly...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28278560/hepatogastric-fistula-as-a-rare-complication-of-pyogenic-liver-abscess
#9
Kyu Won Lee, Hee Yeon Kim, Chang Wook Kim, Young Ki Kim, Ohbeom Kwon, Min Ah Kim, Youngyun Cho, Keungmo Yang
Hepatogastric fistula following a pyogenic liver abscess is extremely rare, and only a handful of cases have been reported. An 88-year-old female presented with generalized weakness, fever and chills. An abdominal computed tomography scan revealed a 5cm-sized hypodense lesion with internal septa in the left lateral section of the liver. Due to initial suspicion of early liver abscess, she was treated with empirical intravenous antibiotics. Initially, aspiration or drainage of the liver abscess was not performed due to immature lesion characteristics...
March 9, 2017: Clinical and Molecular Hepatology
https://www.readbyqxmd.com/read/28270284/effects-of-the-saline-flush-on-high-pitch-ct-coronary-angiography-on-third-generation-dual-source-ct-system
#10
Man Wang, Yining Wang, Yan Yi, Yun Wang, Peijun Liu, Zhengyu Jin
Objective To preliminarily investigate and optimize the saline flush effects to the image quality (IQ)and effective scan rate of high-pitch CT coronary angiography (CCTA)using ultra-low contrast media (CM)protocols on third-generation dual-source CT (DCST). Methods Sixty-eight consecutive patients with suspected or known coronary artery disease (CAD)were recruited and underwent prospective high-pitch CCTA on third-generation DSCT with automatic tube voltage selection (70-80 kV)based ultra-low CM protocols:18 ml(3...
February 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/28270283/optimization-of-kv-selection-on-third-generation-high-pitch-dual-source-coronary-ct-angiography-using-ultra-low-contrast-media-protocols-in-patients-with-body-mass-index-between-20-30-kg-m-2-under-automatic-tube-voltage-selection
#11
Ming Wang, Yan Yi, Jian Cao, Yining Wang, Bing Qi, Shuo Ma, Yun Wang
Objective To investigate the application of automatic tube voltage selection (CARE-kV)coronary CT angiography (CCTA)using ultra-low contrast media (CM)protocols in patients with body mass index (BMI)between 20 kg/m(2) and 30 kg/m(2) on third-generation dual-source CT (DSCT). Methods We prospectively included 134 consecutive patients with BMI between 20 kg/m(2) and 30 kg/m(2)who underwent CARE-kV prospective high-pitch CCTA on third-generation DSCT using the ultra-low CM protocols and divided them into two groups according to the CARE-kV results:70 kV group(n=91):65 patients with normal BMI(20 kg/m(2)≤BMI≤25 kg/m(2))and 26 patients with high BMI(25 kg/m(2)<BMI≤30 kg/m(2));and 80 kV group(n=43):12 patients with normal BMI and 31 patients with high BMI...
February 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/28270282/application-of-70-kv-third-generation-high-pitch-dual-source-coronary-ct-angiography-in-patients-with-different-body-mass-index
#12
Yan Yi, Jian Cao, Lu Lin, Lingyan Kong, Shu Jiang, Xiao Li, Peijun Liu, Ming Wang, Man Wang, Yun Wang, Zhengyu Jin, Yining Wang
Objective  To investigate the optimized range of body mass index (BMI) selection for patients undergoing 70 kV high-pitch dual-source coronary CT angiography (CCTA) on the third-generation dual-source CT (DSCT). Methods  Patients undergoing prospective high-pitch ultra-low contrast media (CM) CCTA on the third-generation DSCT using the automatic tube voltage selection at 70 kV were included and divided into three groups:group A,with BMI≤24 kg/m(2);group B,with 24 kg/m(2)<BMI<28 kg/m(2);and group C,with BMI≥28 kg/m(2)...
February 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/28267554/is-gender-still-a-predisposing-factor-in-contrast-media-associated-adverse-drug-reactions-a-systematic-review-and-meta-analysis-of-randomized-trials-and-observational-studies
#13
Heeyoung Lee, Seungyeon Song, Yun-Kyoung Oh, WonKu Kang, Eunyoung Kim
OBJECTIVE: To evaluate the role of gender as a risk factor for developing contrast media-associated adverse drug reactions (CM-ADRs) by comparing the incidence of CM-ADR between male and female patients according to study design, ADR type, and computed tomography (CT) examination. MATERIAL AND METHODS: We systematically searched three electronic databases for eligible studies. In the studies included (n=18), we assessed effect estimates of the relative incidence of CM-ADR, analysed by experimental design, ADR type and CT examination...
April 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28264201/contrast-media-administration-in-coronary-computed-tomography-angiography-a-systematic-review
#14
Casper Mihl, Monique Maas, Jakub Turek, Anna Seehofnerova, Ralph T H Leijenaar, Madeleine Kok, Marc B I Lobbes, Joachim E Wildberger, Marco Das
Background Various different injection parameters influence enhancement of the coronary arteries. There is no consensus in the literature regarding the optimal contrast media (CM) injection protocol. The aim of this study is to provide an update on the effect of different CM injection parameters on the coronary attenuation in coronary computed tomographic angiography (CCTA). Method Studies published between January 2001 and May 2014 identified by Pubmed, Embase and MEDLINE were evaluated. Using predefined inclusion criteria and a data extraction form, the content of each eligible study was assessed...
March 6, 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28261636/safety-and-efficacy-of-a-high-performance-graphene-based-magnetic-resonance-imaging-contrast-agent-for-renal-abnormalities
#15
Shruti Kanakia, Jimmy Toussaint, Praveen Kukarni, Stephen Lee, Sayan Mullick Chowdhury, Slah Khan, Sandeep K Mallipattu, Kenneth R Shroyer, William Moore, Balaji Sitharaman
The etiology of renal insufficiency includes primary (e.g polycystic kidney disease) or secondary (e.g. contrast media, diabetes) causes. The regulatory restrictions placed on the use of contrast agents (CAs) for non-invasive imaging modalities such as X-ray computed tomography (CT) and magnetic resonance imaging (MRI) affects the clinical management of these patients. With the goal to develop a next-generation CA for unfettered use for renal MRI, here we report, in a rodent model of chronic kidney disease, the preclinical safety and efficacy of a novel nanoparticle CA comprising of manganese (Mn(2+)) ions intercalated graphene coated with dextran (hereafter called Mangradex)...
December 2016: Graphene Technol
https://www.readbyqxmd.com/read/28260170/usefulness-of-3d-balanced-turbo-field-echo-mr-sequence-evaluating-the-branching-pattern-of-the-intrahepatic-bile-ducts-comparison-with-drip-infusion-ct-cholangiography
#16
Masaki Ogawa, Yoshiyuki Ozawa, Kengo Ohta, Tomoya Sekiguchi, Shingo Omata, Misugi Urano, Yoichi Matsuo, Yuta Shibamoto
PURPOSE: For liver surgery, it is crucial to preoperatively examine the course of the right posterior bile duct. While MR cholangiopancreatography (MRCP) can only visualize the bile ducts, 3D balanced turbo-field-echo (BTFE) sequence clearly depicts the bile ducts and portal veins as well as drip infusion CT cholangiography (DIC-CT), without contrast media. We evaluated whether BTFE could substitute for DIC-CT. MATERIALS AND METHODS: Thirty patients undergoing MRCP and BTFE on 1...
March 4, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28257970/effects-of-two-types-of-medical-contrast-media-on-routine-chemistry-results-by-three-automated-chemistry-analyzers
#17
Yu Jin Park, John Hoon Rim, Jisook Yim, Sang-Guk Lee, Jeong-Ho Kim
OBJECTIVES: The use of iodinated contrast media has grown in popularity in the past two decades, but relatively little attention has been paid to the possible interferential effects of contrast media on laboratory test results. Herein, we investigate medical contrast media interference with routine chemistry results obtained by three automated chemistry analyzers. METHODS: Ten levels of pooled serum were used in the study. Two types of medical contrast media [Iopamiro (iopamidol) and Omnipaque (iohexol)] were evaluated...
February 28, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/28257508/longitudinal-changes-of-ocular-blood-flow-using-laser-speckle-flowgraphy-during-normal-pregnancy
#18
Takahiro Sato, Junichi Sugawara, Naoko Aizawa, Noriyuki Iwama, Fumiaki Takahashi, Michiyo Nakamura-Kurakata, Masatoshi Saito, Takashi Sugiyama, Hiroshi Kunikata, Toru Nakazawa, Nobuo Yaegashi
PURPOSE: Innovative laser speckle flowgraphy (LSFG) enables noninvasive evaluation of retinal microcirculation and the usefulness has been reported in the field of ophthalmology. LSFG has allowed us to measure the real time changes of retinal blood flow without pupillary dilatations and contrast media. Herein, we investigated the change of retinal blood flow in normal pregnant women during gestation using LSFG. METHODS: A prospective cohort study was conducted in 53 pregnant women who visited our institution between January, 2013 and July, 2014...
2017: PloS One
https://www.readbyqxmd.com/read/28255790/-contrast-enhanced-ultrasound-ceus-of-the-liver-critical-evaluation-of-use-in-clinical-routine-diagnostics
#19
K Müller-Peltzer, J Rübenthaler, M Reiser, D-A Clevert
CLINICAL/METHODICAL ISSUE: Focal liver lesions are common incidental findings in abdominal ultrasound diagnostics. STANDARD RADIOLOGICAL METHODS: Characterization of focal liver lesions solely based on b‑mode and color duplex is not feasible in all cases. METHODICAL INNOVATIONS: Using contrast-enhanced ultrasound (CEUS) it is possible to dynamically visualize the vascularization of focal liver lesions, which enables the characterization of benign and malignant liver tumors...
March 2, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28249309/iodinated-contrast-media-and-the-alleged-iodine-allergy-an-inexact-diagnosis-leading-to-inferior-radiologic-management-and-adverse-drug-reactions
#20
Ingrid Böhm, Knud Nairz, John N Morelli, Patricia Silva Hasembank Keller, Johannes T Heverhagen
Purpose To test the hypothesis that the incomplete diagnosis "iodine allergy" is a possibly dangerous concept for patients under routine radiologic conditions. Materials and Methods 300 patients with a history of an "iodine allergy" were retrospectively screened and compared with two age-, sex-, and procedure-matched groups of patients either diagnosed with a nonspecific "iodine contrast medium (ICM) allergy" or an allergy to a specific ICM agent. For all groups, the clinical symptoms of the most recent past adverse drug reaction (ADR), prophylactic actions taken for subsequent imaging, and ultimate outcome were recorded and analyzed...
March 1, 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
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