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https://www.readbyqxmd.com/read/28815859/performance-of-mri-for-suspected-appendicitis-in-pediatric-patients-and-negative-appendectomy-rate-a-systematic-review-and-meta-analysis
#1
Jeong Rye Kim, Chong Hyun Suh, Hee Mang Yoon, Ah Young Jung, Jin Seong Lee, Jung Heon Kim, Jeong-Yong Lee, Young Ah Cho
PURPOSE: To evaluate in pediatric patients the diagnostic performance of magnetic resonance imaging (MRI) for suspected appendicitis and its negative appendectomy rate. MATERIALS AND METHODS: The study involved diagnostic accuracy studies that used MRI for pediatric patients with suspected appendicitis. Various field strengths and sequences were used in each included study. The diagnostic accuracy of MRI in pediatric patients with suspected appendicitis and negative appendectomy rate were assessed...
August 17, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28809582/iodixanol-versus-iopromide-at-coronary-ct-angiography-lumen-opacification-and-effect-on-heart-rhythm-the-randomized-isocor-trial
#2
Marisa M Lubbers, Marc Kock, André Niezen, Tjebbe Galema, Marcel Kofflard, Tobias Bruning, Henriette S Kooij, Hanneke van Valen, Marcel Dijkshoorn, Ronald Booij, Anthony Padmos, Alain Vogels, Ricardo P J Budde, Koen Nieman
Purpose To show that equal coronary lumen opacification can be achieved with iso- and low-osmolar contrast media when it is injected at the same iodine delivery rate with contemporary cardiac computed tomographic (CT) protocols and to investigate the cardiovascular effect of iso-osmolar contrast media and the image quality achieved. Materials and Methods Institutional review board approval and written informed consent were obtained for the Effect of Iso-osmolar Contrast Medium on Coronary Opacification and Heart Rhythm in Coronary CT Angiography, or IsoCOR, trial...
August 15, 2017: Radiology
https://www.readbyqxmd.com/read/28806208/systemic-hypotension-following-intravenous-administration-of-nonionic-contrast-medium-during-computed-tomography-iopromide-versus-iodixanol
#3
Gerlig Widmann, Reto Bale, Hanno Ulmer, Daniel Putzer, Peter Schullian, Franz-Josef Wiedermann, Wolfgang Lederer
BACKGROUND: In light of the increasing number of radiologic interventions performed under general anesthesia, the effects of contrast media (CM) on circulation and organ perfusion are of paramount importance. The objectives of this study were to systematically quantify effects on blood pressure, heart rate, and kidney function following intravenous administration of nonionic CM with normal and low osmolality. METHODS: In this controlled, double-blinded phase IV clinical trial, 40 consecutive patients were randomly assigned to receive repeated measures of either low-osmolar iopromide or iso-osmolar iodixanol...
August 10, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28800951/evaluation-of-a-high-concentrated-contrast-media-injection-protocol-in-combination-with-low-tube-current-for-dose-reduction-in-coronary-computed-tomography-angiography-a-randomized-two-center-prospective-study
#4
Yibo Sun, Yanqing Hua, Mingpeng Wang, Dingbiao Mao, Xiu Jin, Cheng Li, Kailei Shi, Jianrong Xu
RATIONALE AND OBJECTIVES: The study aimed to prospectively evaluate the radiation dose reduction potential and image quality (IQ) of a high-concentration contrast media (HCCM) injection protocol in combination with a low tube current (mAs) in coronary computed tomography angiography. MATERIALS AND METHODS: Eighty-one consecutive patients (mean age: 62 years; 34 females; body mass index: 18-31) were included and randomized-assigned into two groups. All computed tomography (CT) examinations were performed in two groups with the same tube voltage (100 kV), flow rate of contrast medium (5...
August 8, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28799717/persistent-serum-creatinine-increase-following-contrast-induced-acute-kidney-injury
#5
Carlo Briguori, Cristina Quintavalle, Francesca De Micco, Gabriella Visconti, Vito Di Palma, Giovanni Napolitano, Amelia Focaccio, Gerolama Condorelli
BACKGROUND: Contrast-induced acute kidney injury (CI-AKI) may led to both a transient and a persistent serum creatinine (sCr) increase. OBJECTIVES: To assess whether serum cystatin C (sCyC) and urine and serum neutrophil gelatinase-associated lipocalin (uNGAL, sNGAL) are useful in the early identification of persistent sCr increase following CI-AKI. METHODS: One hundred and eighteen patients who developed CI-AKI were included into the study...
August 11, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28781307/isolated-right-ventricular-stress-takotsubo-cardiomyopathy
#6
Hitoshi Sumida, Kenji Morihisa, Kazuhiro Katahira, Seigo Sugiyama, Takuya Kishi, Shuichi Oshima
A 79-year-old woman was admitted with a left femoral neck fracture and she immediately developed circulatory shock. Echocardiography showed a markedly enlarged right ventricle (RV) with systolic ballooning of the mid-ventricular wall and preserved contractility of the apex. The left ventricular (LV) motion was normal. Multi-detector-row computed tomography showed severe congestion of the contrast media in the right atrium with no forward flow to RV, but no pulmonary embolism. She was successfully treated with percutaneous veno-arterial extracorporeal membrane oxygenation...
August 1, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28774741/histopathological-evaluation-and-redox-assessment-in-blood-and-kidney-tissues-in-a-rabbit-contrast-induced-nephrotoxicity-model
#7
Maria-Malvina Tsamouri, Maria Rapti, Paraskevi Kouka, Charitini Nepka, Konstantinos Tsarouhas, Anestis Soumelidis, George Koukoulis, Aristides Tsatsakis, Demetrios Kouretas, Christina Tsitsimpikou
Contrast-induced nephropathy (CIN) is a leading cause of hospital-acquired acute kidney injury as a result of iodinated contrast-media use for diagnostic purposes. Pathophysiology remains unclear. In the present study iopromide was administered to New Zealand white rabbits without any prior intervention. Oxidative stress was assessed in blood and tissue level at three anatomical kidney areas (medullary, cortical, juxtamedullary). Histopathological evaluation was also performed. Serum creatinine and urea increased in the CIN groups over 25% at two hours after administration and returned to baseline at 48 h...
July 31, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28774606/the-impact-of-iodinated-x-ray-contrast-agents-on-formation-and-toxicity-of-disinfection-by-products-in-drinking-water
#8
Clara H Jeong, Edward J Machek, Morteza Shakeri, Stephen E Duirk, Thomas A Ternes, Susan D Richardson, Elizabeth D Wagner, Michael J Plewa
The presence of iodinated X-ray contrast media (ICM) in source waters is of high concern to public health because of their potential to generate highly toxic disinfection by-products (DBPs). The objective of this study was to determine the impact of ICM in source waters and the type of disinfectant on the overall toxicity of DBP mixtures and to determine which ICM and reaction conditions give rise to toxic by-products. Source waters collected from Akron, OH were treated with five different ICMs, including iopamidol, iopromide, iohexol, diatrizoate and iomeprol, with or without chlorine or chloramine disinfection...
August 2017: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/28767406/effect-of-trimetazidine-on-preventing-contrast-induced-nephropathy-in-diabetic-patients-with-renal-insufficiency
#9
Ziliang Ye, Haili Lu, Qiang Su, Xinhua Xian, Lang Li
BACKGROUND: Our study sought to assess the effect of trimetazidine (TMZ) on preventing contrast-induced nephropathy (CIN) in diabetic patients with renal insufficiency. MATERIALS AND METHODS: 106 diabetic patients with renal insufficiency who were undergoing coronary angiography (CAG) and/or percutaneous coronary intervention (PCI) were enrolled in this study. Standard hydration was administered to both groups (the TMZ group and the control group). In the TMZ group, patients were orally administered TMZ for 48 hours before and 24 hours after CAG and/or PCI...
July 24, 2017: Oncotarget
https://www.readbyqxmd.com/read/28766981/image-quality-and-radiation-dose-of-ct-venography-with-double-dose-reduction-using-model-based-iterative-reconstruction-comparison-with-conventional-ct-venography-using-filtered-back-projection
#10
Yeo-Jin Jeong, Ki Seok Choo, Kyung Jin Nam, Ji Won Lee, Jin You Kim, Hyuk Jae Jung, Soo Jin Lim
Background Computed tomography venography (CTV) at low kVp using model-based iterative reconstruction (MBIR) can enhance vascular enhancement with noise reduction. Purpose To evaluate image qualities and radiation doses of CTV at 80 kVp using MBIR and a small iodine contrast media (CM) dose and to compare these with those of CTV performed using a conventional protocol. Material and Methods Sixty-five patients (mean age = 58.1 ± 7.2 years) that underwent CTV for the evaluation of deep vein thrombosis (DVT) and varicose veins were enrolled in this study...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28759794/iodinated-trihalomethane-formation-during-chloramination-of-iodate-containing-waters-in-the-presence-of-zero-valent-iron
#11
Ying Xia, Yi-Li Lin, Bin Xu, Chen-Yan Hu, Ze-Chen Gao, Wen-Hai Chu, Nai-Yun Gao
Iodide (I(-)) and iodinated X-ray contrast media (ICM) are the primary iodine sources for the formation of iodinated disinfection byproducts (I-DBPs), and iodate (IO3(-)) is believed to be a desired sink of iodine in water. This study found that highly cytotoxic iodinated trihalomethanes (I-THMs) also can be generated from iodate-containing waters (without any other iodine sources) in the presence of zero valent iron (ZVI) during chloramination, which could be a big issue in the wide usage of iron pipes. The effect of major factors including ZVI dosage, NH2Cl and IO3(-) concentrations, initial pH, Br(-)/IO3(-) molar ratio, phosphate concentration, iron corrosion scales (goethite and hematite) on the formation of I-THMs were investigated...
July 24, 2017: Water Research
https://www.readbyqxmd.com/read/28739144/contrast-enhancement-in-breast-cancer-and-background-mammary-gland-tissue-during-the-super-early-phase-of-dynamic-breast-magnetic-resonance-imaging
#12
Tetsuya Tomida, Atsushi Urikura, Takayoshi Uematsu, Kensei Shirata, Yoshihiro Nakaya
RATIONALE AND OBJECTIVES: We aimed to compare the contrast enhancement between tumor and mammary-gland tissue to distinguish lesions in the super-early phase, during which minimal contrast media uptake is observed in mammary-gland tissue. MATERIALS AND METHODS: Dynamic magnetic resonance imaging, including the super-early phase with bolus tracking (BT) method (to determine the optimal imaging start time), was performed by using identical parameters to obtain transverse fat-suppressed T1-weighted images of both breasts...
July 21, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28731176/hypotonic-contrast-media-is-more-toxic-than-isotonic-contrast-media-on-endothelial-cells-in-vivo-and-in-vitro
#13
Lihui Ren, Ping Wang, Zuoyan Wang, Yong Liu, Shuzheng Lv
The aim of the current study was to investigate the cytotoxic effects of hypotonic (iopamidol) and isotonic (iodixanol) contract media (CMs) in vitro and in vivo. A total of 60 Wistar rats were included and were randomly divided into three groups (20 rats per group). Iodixanol (4 g iodine/kg), iopamidol (4 g iodine/kg) or equal volume of normal saline was injected via tail vein. HUVEC and H5V cell viability was determined by Cell Counting Kit‑8 agents. Western blotting was performed to detect ATP‑binding cassette subfamily G member 1 (ABCG1) expression...
July 21, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28730872/a-dual-label-time-resolved-fluorescence-immunoassay-for-the-simultaneous-determination-of-cystatin-c-and-%C3%AE-2-microglobulin-in-urine
#14
Y Liu, Y H Liu, W J Bei, K Wang, T T Cui, H L Li, D X Wu, S Q Chen, N Tan, J Y Chen
BACKGROUND: Contrast media is widely used in clinical diagnostic and interventional procedures, but may cause damage to the kidney, that is, contrast-induced nephropathy. This study was to establish a dual-label time-resolved fluorescence immunoassay (TRFIA) for the simultaneous determination of renal function markers cystatin-C (Cys-C) and β2-microglobulin (β2-MG) for the early diagnosis and follow-up surveillance of contrast-induced nephropathy. METHODS: A sandwich immunoassay was used to detect the concentration of Cys-C, and the competitive immunoassay was used to detect the concentration of β2-MG in 50 samples of urine...
July 21, 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28726528/the-predictive-value-of-the-product-of-contrast-medium-volume-and-urinary-albumin-creatinine-ratio-in-contrast-induced-acute-kidney-injury
#15
Chunrui Wang, Shuai Ma, Bo Deng, Jianxin Lu, Wei Shen, Bo Jin, Haiming Shi, Feng Ding
Preexisting renal impairment and the amount of contrast media are the most important risk factors for contrast-induced acute kidney injury (CI-AKI). We aimed to investigate whether the product of contrast medium volume and urinary albumin/creatinine ratio (CMV × UACR) would be a better predictor of CI-AKI in patients undergoing nonemergency coronary interventions. This was a prospective single-center observational study, and 912 consecutive patients who were exposed to contrast media during coronary interventions were investigated prospectively...
November 2017: Renal Failure
https://www.readbyqxmd.com/read/28725558/temperature-dependent-optoacoustic-response-and-transient-through-zero-gr%C3%A3-neisen-parameter-in-optically-contrasted-media
#16
Elena Petrova, Anton Liopo, Alexander A Oraevsky, Sergey A Ermilov
Non-invasive optoacoustic mapping of temperature in tissues with low blood content can be enabled by administering external contrast agents. Some important clinical applications of such approach include temperature mapping during thermal therapies in a prostate or a mammary gland. However, the technique would require a calibration that establishes functional relationship between the measured normalized optoacoustic response and local tissue temperature. In this work, we investigate how a key calibration parameter - the temperature of zero optoacoustic response (T0 ) - behaves in different environments simulating biological tissues augmented with either dissolved or particulate (nanoparticles) contrast agents...
September 2017: Photoacoustics
https://www.readbyqxmd.com/read/28720373/incidence-of-adverse-contrast-reaction-following-nonintravenous-urinary-tract-imaging
#17
Robert H Blackwell, Eric J Kirshenbaum, Matthew A C Zapf, Anai N Kothari, Paul C Kuo, Robert C Flanigan, Gopal N Gupta
Adverse reactions (ARs) to intravenous (IV) radiographic contrast range from mild urticaria to life-threatening anaphylaxis. Intraluminal contrast dye is routinely used in the urinary tract with a minimal perceived risk of AR. We used the Healthcare Cost and Utilization Project State Inpatient Databases for California and Florida from 2007 to 2011 to identify patients who received urinary tract contrast dye for retrograde pyelography, percutaneous pyelography, retrograde/other cystogram, and ileal conduitogram...
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28708716/the-influence-of-contrast-agent-s-osmolarity-on-iodine-delivery-protocol-in-coronary-computed-tomography-angiography-comparison-between-iso-osmolar-iodixanol-320-and-low-osmolar-iomeprol-370
#18
Xiaohan Yang, Weiwei Huang, Wangyan Liu, Yinsu Zhu, Yi Xu, Guanyu Yang, Lijun Tang, Xiaomei Zhu
OBJECTIVES: This study aims to assess whether iodine-contained contrast agents with different osmolarity affect iodine delivery protocol during coronary computed tomography angiography (CCTA). METHODS: Patients who underwent CCTA were randomized to receive contrast media either iodixanol-320 (iso-osmolar group) or iopromide-370 (low-osmolar group). Contrast protocols were recorded. Tube voltage of 100 kV was chosen for patients with body mass index of less than or equal to 25 (n = 224) and tube voltage of 120 kV for patients with body mass index of greater than 25 (n = 165)...
July 13, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28707094/primary-and-secondary-percutaneous-ureteral-stent-placement-comparison-of-stent-patency-and-clinical-outcome
#19
Seo Yeon Youn, Jung Suk Oh, Hae Giu Lee, Byung Gil Choi, Ho Jong Chun, Eu Hyun Kim
OBJECTIVES: To compare early double J ureteral stent (DJUS) dysfunction rate and long-term patency between two percutaneous ureteral stent placement methods: single-stage (primary) or two-stage (secondary) procedures. METHODS: A total of 250 (176 primary and 74 secondary) DJUS placements performed on interventional unit were retrospectively reviewed between February 2008 and March 2014. Early DJUS dysfunction was defined as no passage of contrast media into the urinary bladder in 2-3 days after placement...
July 13, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28706806/osseoscopy-direct-visualization-to-assist-core-decompression-and-debridement-of-necrotic-bone-defects
#20
William C Geisert, Aaron M Perdue, Kagan Ozer
Free vascularized fibular grafting after core decompression and debridement of necrotic lesions is an effective surgical treatment of avascular necrosis of the femoral head. A technical challenge encountered in performing this procedure is ensuring adequate debridement of necrotic parts while preserving healthy bone. A previously described method accomplishes this indirectly using radioactive contrast media and fluoroscopy, increasing the risk of radiation exposure. We propose a surgical technique using standard arthroscopic equipment to visualize inside the femoral head, facilitating precise and accurate debridement without additional radiation exposure...
June 2017: Arthroscopy Techniques
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