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https://www.readbyqxmd.com/read/28445910/influence-of-contrast-media-on-bone-mineral-density-bmd-measurements-from-routine-contrast-enhanced-mdct-datasets-using-a-phantom-less-bmd-measurement-tool
#1
Andrea Toelly, Constanze Bardach, Michael Weber, Rui Gong, Yanbo Lai, Pei Wang, Yulin Guo, Jan Kirschke, Thomas Baum, Michael Gruber
Aim To evaluate the differences in phantom-less bone mineral density (BMD) measurements in contrast-enhanced routine MDCT scans at different contrast phases, and to develop an algorithm for calculating a reliable BMD value. Materials and Methods 112 postmenopausal women from the age of 40 to 77 years (mean age: 57.31 years; SD 9.61) who underwent a clinically indicated MDCT scan, consisting of an unenhanced, an arterial, and a venous phase, were included. A retrospective analysis of the BMD values of the Th12 to L4 vertebrae in each phase was performed using a commercially available phantom-less measurement tool...
April 26, 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28443376/remote-ischemic-conditioning-and-renal-protection
#2
Georgios Giannopoulos, Dimitrios A Vrachatis, Vasiliki Panagopoulou, Manolis Vavuranakis, Michael W Cleman, Spyridon Deftereos
Over the course of the last 2 decades, the concept of remote ischemic conditioning (RIC) has attracted considerable research interest, because RIC, in most of its embodiments offers an inexpensive way of protecting tissues against ischemic damage inflicted by a number of medical conditions or procedures. Acute kidney injury (AKI) is a common side effect in the context of various medical procedures, and RIC has been suggested as a means of reducing its incidence. Outcomes regarding kidney function have been reported in numerous studies that evaluated the effects of RIC in a variety of settings (eg, cardiac surgery, interventions requiring intravenous administration of contrast media)...
January 1, 2017: Journal of Cardiovascular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28439760/prognostic-study-of-cardiac-events-in-japanese-patients-with-chronic-kidney-disease-using-ecg-gated-myocardial-perfusion-imaging-final-3-year-report-of-the-j-access-3-study
#3
Satoko Nakamura, Yuhei Kawano, Kenichi Nakajima, Hiroki Hase, Nobuhiko Joki, Tsuguru Hatta, Shigeyuki Nishimura, Masao Moroi, Susumu Nakagawa, Tokuo Kasai, Hideo Kusuoka, Yasuchika Takeishi, Mitsuru Momose, Kazuya Takehana, Mamoru Nanasato, Syunichi Yoda, Hidetaka Nishina, Naoya Matsumoto, Tsunehiko Nishimura
BACKGROUND: Myocardial perfusion imaging (MPI) is considered useful for risk stratification among patients with chronic kidney disease (CKD), without renal deterioration by contrast media. METHODS AND RESULTS: The Japanese Assessment of Cardiac Events and Survival Study by Quantitative Gated SPECT (J-ACCESS 3) is a multicenter, prospective cohort study investigating the ability of MPI to predict cardiac events in 529 CKD patients without a definitive coronary artery disease...
April 24, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28437011/noise-reduction-and-functional-maps-image-quality-improvement-in-dynamic-ct-perfusion-using-a-new-k-means-clustering-guided-bilateral-filter-kmgb
#4
Francesco Pisana, Thomas Henzler, Stefan Schönberg, Ernst Klotz, Bernhard Schmidt, Marc Kachelrieß
PURPOSE: Dynamic CT perfusion (CTP) consists in repeated acquisitions of the same volume in different time steps, slightly before, during and slightly afterwards the injection of contrast media. Important functional information can be derived for each voxel, which reflect the local hemodynamic properties and hence the metabolism of the tissue. Different approaches are being investigated to exploit data redundancy and prior knowledge for noise reduction of such datasets, ranging from iterative reconstruction schemes to high dimensional filters...
April 24, 2017: Medical Physics
https://www.readbyqxmd.com/read/28428469/verification-of-the-injection-pressure-reduction-effect-using-the-novel-indwelling-needle-for-contrast-enhanced-ct
#5
Daiki Watanabe, Masaaki Fukunaga, Hiroyuki Yamamoto
PURPOSE: The purpose of this study was to investigate the injection pressure reduction effect of the novel indwelling needle (Becton, Dickinson and Company). METHOD: We evaluated the period of 651 patients who underwent dynamic computed tomography. We compared the maximum injection pressure. The contrast medium was administered at 320, 350, and 370 mgI/ml. RESULT: The maximum injection pressure of the novel indwelling needle in 22 G was decreased 10% compared with SC5 in all contrast media...
2017: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/28424042/the-effect-of-a-new-angiographic-imaging-technology-on-radiation-dose-in-visceral-embolization-procedures
#6
Frederic Baumann, Constantino Peña, Roman Kloeckner, Barry T Katzen, Ripal Gandhi, James B Benenati
PURPOSE: To evaluate the impact of a new angiographic imaging technology on radiation dose during visceral embolization procedures involving both fluoroscopy and digital subtraction angiography. MATERIAL AND METHODS: A retrospective analysis from a single-center consecutive series of patients was performed comparing 2 angiographic imaging systems. The AlluraClarity (CIQ; Philips Healthcare, Best, the Netherlands) was used in 100 patients (n = 59 male, mean age: 70...
May 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28412091/lansoprazole-halts-contrast-induced-nephropathy-through-activation-of-nrf2-pathway-in-rats
#7
Sahar A Khaleel, Amany A Alzokaky, Nahed A Raslan, Asmaa I Alwakeel, Heba G Abd El-Aziz, Adel R Abd-Allah
Contrast-induced nephropathy (CIN) is an important cause of acute kidney injury characterized by significant mortality and morbidity. To date, there is no successful protective regimen for CIN especially in poor kidney function patients. Lansoprazole has been shown to exert antioxidant action through induction of nuclear factor-erythroid 2-related factor 2 (Nrf2) pathway. The aim of the present study is to investigate the potential of lansoprazole to activate Nrf2 pathway in the kidney and consequently to protect against oxidative stress induced by iodinated contrast media...
April 13, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/28412022/acute-kidney-injury-is-associated-with-microvascular-myocardial-damage-following-myocardial-infarction
#8
Sebastian Johannes Reinstadler, Andreas Kronbichler, Martin Reindl, Hans-Josef Feistritzer, Veronika Innerhofer, Agnes Mayr, Gert Klug, Martin Tiefenthaler, Gert Mayer, Bernhard Metzler
Acute kidney injury (AKI) is a frequent complication in patients with ST-elevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention. However, the pathophysiology of AKI in this setting is complex and goes beyond the administration of contrast media. Studies assessing the impact of infarct characteristics on AKI are currently lacking. Therefore, we investigated the association of AKI with myocardial as well as microvascular injury in an initial total of 361 consecutive STEMI patients treated by primary percutaneous coronary intervention...
April 12, 2017: Kidney International
https://www.readbyqxmd.com/read/28409250/gadolinium-based-contrast-agents-in-pediatric-magnetic-resonance-imaging
#9
REVIEW
Eric M Gale, Peter Caravan, Anil G Rao, Robert J McDonald, Matthew Winfeld, Robert J Fleck, Michael S Gee
Gadolinium-based contrast agents can increase the accuracy and expediency of an MRI examination. However the benefits of a contrast-enhanced scan must be carefully weighed against the well-documented risks associated with administration of exogenous contrast media. The purpose of this review is to discuss commercially available gadolinium-based contrast agents (GBCAs) in the context of pediatric radiology. We discuss the chemistry, regulatory status, safety and clinical applications, with particular emphasis on imaging of the blood vessels, heart, hepatobiliary tree and central nervous system...
May 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28407291/use-of-contrast-media-in-computed-tomography-and-magnetic-resonance-imaging-in-horses-techniques-adverse-events-and-opportunities
#10
REVIEW
B B Nelson, L R Goodrich, M F Barrett, M W Grinstaff, C E Kawcak
The use of contrast media in computed tomography (CT) and magnetic resonance imaging (MRI) is increasing in horses. These contrast-enhanced imaging techniques provide improved tissue delineation and evaluation thereby expanding diagnostic capabilities. While generally considered safe, not all contrast media exhibit the same safety profiles. The safety of contrast media use and descriptions of adverse events occurring in horses are sparsely reported. This review summarises the reported evidence of contrast media use and adverse events that occur in horses, with added contribution from other veterinary species and human studies for comparison...
April 13, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28401790/comparison-of-iodixanol-and-iopromide-in-patients-with-renal-insufficiency-and-congestive-heart-failure-undergoing-coronary-angiography-by-hemodynamic-monitoring
#11
Geng Qian, Yong-Qiang Yang, Wei Dong, Feng Cao, Yun-Dai Chen
We investigated the impact of contrast media (CM) with different osmolality on cardiac preload in patients with chronic kidney disease (CKD) and congestive heart failure (CHF). Patients with CKD and CHF were equally randomized to receive either iso-osmolar contrast media (IOCM) iodixanol or low-osmolar contrast media iopromide. We measured cardiac preload indexes by invasive hemodynamic monitoring before and after CM injection. Major adverse cardiac events postprocedures were recorded. Increase in extravascular lung water index was only seen in the iopromide group ( P < ...
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/28387639/effect-of-intravenous-administration-of-contrast-media-on-serum-creatinine-levels-in-neonates
#12
Maria A Bedoya, Ammie M White, J Christopher Edgar, Madhura Pradhan, Elisabeth L Raab, James S Meyer
Purpose To assess the effect of intravenous contrast media on renal function in neonates. Materials and Methods Institutional review board approval was obtained with waiver of consent. Electronic health records from January 2011 to April 2013 were reviewed retrospectively. Measures of renal function were obtained in inpatient neonates who underwent magnetic resonance (MR) imaging or computed tomography (CT) and for whom serum creatinine (Cr) levels were obtained within 72 hours before imaging and at least one time after imaging (>1 day after administration of contrast material)...
April 6, 2017: Radiology
https://www.readbyqxmd.com/read/28382626/use-of-radiocontrast-agents-in-ckd-and-esrd
#13
Jehan Z Bahrainwala, Amanda K Leonberg-Yoo, Michael R Rudnick
Contrast exposure in a population with chronic kidney disease (CKD) requires additional consideration given the risk of contrast-induced nephropathy (CIN) after exposure to iodinated contrast as well as systemic injury with exposure to gadolinium-based contrast agents (GBCA). Strategies to avoid CIN, and manage patients after exposure, including extracorporeal removal of contrast media, may differ among an advanced CKD population as compared to a general population. There is strong evidence to support the use of isotonic volume expansion and the lowest dose of low-osmolar or iso-osmolar contrast media possible to decrease CIN...
April 5, 2017: Seminars in Dialysis
https://www.readbyqxmd.com/read/28377923/dynamic-susceptibility-contrast-magnetic-resonance-imaging-protocol-of-the-normal-canine-brain
#14
Krystina L Stadler, Anthony P Pease, Elizabeth A Ballegeer
Perfusion magnetic resonance imaging (MRI), specifically dynamic susceptibility MRI (DSC-MRI) is routinely performed as a supplement to conventional MRI in human medicine for patients with intracranial neoplasia and cerebrovascular events. There is minimal data on the use of DSC-MRI in veterinary patients and a DSC-MRI protocol in the veterinary patient has not been described. Sixteen normal dogs, 6 years or older were recruited for this study. The sample population included 11 large dogs (>11 kg) and 5 small dogs (<11 kg)...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28377907/initial-clinical-experience-with-the-endologix-afx-unibody-stent-graft-system-for-treating-patients-with-abdominal-aortic-aneurysms-a-case-controlled-comparative-study
#15
George N Kouvelos, Petroula Nana, Vasilios Bouris, Michalis Peroulis, Aikaterini Drakou, Nikolaos Rousas, Athanasios Giannoukas, Miltiadis I Matsagkas
PURPOSE: The newly designed unibody AFX endograft system for endovascular aortic aneurysm repair is the only graft with anatomical fixation to the aortic bifurcation in comparison to most other grafts that use the infrarenal neck as the main fixation point. The aim of this study was to assess the preliminary results of the AFX stent-graft system used with infrarenal aortic component and compare them with those obtained in patients treated with a well established endograft of the same material and pure infrarenal fixation as the Gore Excluder...
March 2017: Vascular Specialist International
https://www.readbyqxmd.com/read/28372322/interactions-between-iodinated-contrast-media-and-tissue-plasminogen-activator-in-vitro-comparison-study
#16
Eszter Vörös, László Deres, Róbert Halmosi, Edit Váradi, Kálmán Tóth, István Battyáni
BACKGROUND AND PURPOSE: Iodinated contrast media (Xenetix®, Ultravist®, Omnipaque®, Visipaque® and Iomeron®) used for computed tomography (CT) may decrease fibrinolysis by recombinant tissue plasminogen activator (rt-PA). We hypothesized that receiving iodinated contrast media before rt-PA may impair thrombolysis as measured by a new model system. METHODS: Whole blood from Wistar Kyoto rats (n = 10) was obtained and allowed to form blood clots. Thrombolysis was performed by placing individually the prepared clots into 15 mL tubes and adding 5 mL saline buffer, 100μg rt-PA and a different contrast media; adjusting the quantity of iodine to either 30 mg or 60 mg...
March 30, 2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/28368880/critical-questions-regarding-gadolinium-deposition-in-the-brain-and-body-after-injections-of-the-gadolinium-based-contrast-agents-safety-and-clinical-recommendations-in-consideration-of-the-ema-s-pharmacovigilance-and-risk-assessment-committee-recommendation
#17
Val M Runge
For magnetic resonance, the established class of intravenous contrast media is the gadolinium-based contrast agents. In the 3 decades since initial approval, these have proven in general to be very safe for human administration. However, in 2006, a devastating late adverse reaction to administration of the less stable gadolinium-based contrast agents was identified, nephrogenic systemic fibrosis. The result of actions taken by the European Medicines Agency and the US Food and Drug Administration, stratifying the agents by risk and contraindicating specific agents in severe renal dysfunction, has led to no new cases being identified in North America or Europe...
April 1, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28368879/bowel-angioedema-associated-with-iodinated-contrast-media-incidence-and-predisposing-factors
#18
Nieun Seo, Yong Eun Chung, Joon Seok Lim, Mi Kyung Song, Myeong-Jin Kim, Ki Whang Kim
OBJECTIVE: Bowel angioedema is an acute adverse reaction to iodinated contrast media (CM) that involves the gastrointestinal tract. We aimed to investigate the incidence and predisposing factors of iodinated CM-associated bowel angioedema during computed tomography (CT) examinations. MATERIALS AND METHODS: This study was approved by our institutional review board, and informed consent was waived due to its retrospective design. From July 2013 to July 2015, adult patients with a history of adverse reactions to iodinated CM during CT (group A, n = 427) and patients without adverse reactions matched for age and sex with the propensity-score matching method (group B, n = 427) were studied...
April 1, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28363694/cost-effectiveness-of-eob-mri-for-hepatocellular-carcinoma-in-japan
#19
Akihiro Nishie, Satoshi Goshima, Hiroki Haradome, Etsuro Hatano, Yasuharu Imai, Masatoshi Kudo, Masanori Matsuda, Utaroh Motosugi, Satoshi Saitoh, Kengo Yoshimitsu, Bruce Crawford, Eliza Kruger, Graeme Ball, Hiroshi Honda
PURPOSE: The objective of the study was to evaluate the cost-effectiveness of gadoxetic acid-enhanced magnetic resonance imaging (EOB-MRI) in the diagnosis and treatment of hepatocellular carcinoma (HCC) in Japan compared with extracellular contrast media-enhanced MRI (ECCM-MRI) and contrast media-enhanced computed tomography (CE-CT) scanning. METHODS: A 6-stage Markov model was developed to estimate lifetime direct costs and clinical outcomes associated with EOB-MRI...
March 28, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28361951/qualitative-and-quantitative-imaging-evaluation-of-renal-cell-carcinoma-subtypes-with-grating-based-x-ray-phase-contrast-ct
#20
Margarita Braunagel, Lorenz Birnbacher, Marian Willner, Mathias Marschner, Fabio De Marco, Manuel Viermetz, Susan Notohamiprodjo, Katharina Hellbach, Sigrid Auweter, Vera Link, Christine Woischke, Maximilian F Reiser, Franz Pfeiffer, Mike Notohamiprodjo, Julia Herzen
Current clinical imaging methods face limitations in the detection and correct characterization of different subtypes of renal cell carcinoma (RCC), while these are important for therapy and prognosis. The present study evaluates the potential of grating-based X-ray phase-contrast computed tomography (gbPC-CT) for visualization and characterization of human RCC subtypes. The imaging results for 23 ex vivo formalin-fixed human kidney specimens obtained with phase-contrast CT were compared to the results of the absorption-based CT (gbCT), clinical CT and a 3T MRI and validated using histology...
March 31, 2017: Scientific Reports
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