R E Crawford, L M Bliss, M E Schneider, V K Phelps, R V Gilmore, H K Harris, B E Westendorff, G K Koenig, P C Mashburn, M W Galloway
This experiment evaluated the hydrogen ion (H+) buffering capacity (BC) of solutions and alkalizing agents employed during cardiopulmonary bypass (CPB). A solution's BC can be determined when a known quantity of H+ is titrated into the solution and the change () in pH (-log of the hydrogen ion activity ([H+]a)) is measured ([H+]a/mmole H+). Eleven solutions were studied:Lactated Ringers (LR), 0.9% NaCl (NS), Plasma-Lyte A, Hespan (6% hetastarch), banked donor blood with citrate phosphate dextrose adenine (CPDA-1), fresh donor blood, THAM, sodium bicarbonate (NaHCO3; 1 mEq/ml), high potassium crystalloid cardioplegic solution (HKCCPS), oxygenated crystalloid cardioplegic solution (OCCPS), and adult crystalloid priming solution (AP) per institutional protocol...
September 1995: Journal of Extra-corporeal Technology