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https://www.readbyqxmd.com/read/28426441/diagnosis-of-corneal-limbal-stem-cell-deficiency
#1
Kyeong Hwan Kim, Shahzad I Mian
PURPOSE OF REVIEW: A state of limbal stem cell deficiency (LSCD) can be secondary to a number of etiologies, resulting in either a reduction in the total number of limbal stem cells or an abnormality in stem cell function. Initially, the epithelium becomes irregular and hazy; however, this condition may progress to persistent corneal epithelial defects, stromal scarring, ulceration, and even perforation. Since LSCD secondary to a variety of etiologies may be reversible, and various factors are prognostic of disease progression, timely diagnosis is important...
April 19, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28426162/motion-corrected-simultaneous-cardiac-positron-emission-tomography-and-coronary-mr-angiography-with-high-acquisition-efficiency
#2
Camila Munoz, Radhouene Neji, Gastão Cruz, Andrew Mallia, Sami Jeljeli, Andrew J Reader, Rene M Botnar, Claudia Prieto
PURPOSE: Develop a framework for efficient free-breathing simultaneous whole-heart coronary magnetic resonance angiography (CMRA) and cardiac positron emission tomography (PET) on a 3 Tesla PET-MR system. METHODS: An acquisition that enables nonrigid motion correction of both CMRA and PET has been developed. The proposed method estimates translational motion from low-resolution 2D MR image navigators acquired at each heartbeat and 3D nonrigid respiratory motion between different respiratory bins from the CMRA data itself...
April 20, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28426148/three-dimensional-finite-element-based-deformable-image-registration-for-evaluation-of-pleural-cavity-irradiation-during-photodynamic-therapy
#3
Rozhin Penjweini, Michele M Kim, Timothy C Zhu
PURPOSE: Photodynamic therapy (PDT) is used after surgical resection to treat the microscopic disease for malignant pleural mesothelioma and to increase survival rates. As accurate light delivery is imperative to PDT efficacy, the deformation of the pleural volume during the surgery is studied on its impact on the delivered light fluence. In this study, a three-dimensional finite element-based (3D FEM) deformable image registration is proposed to directly match the volume of lung to the volume of pleural cavity obtained during PDT to have accurate representation of the light fluence accumulated in the lung, heart and liver (organs-at-risk) during treatment...
April 20, 2017: Medical Physics
https://www.readbyqxmd.com/read/28426025/modular-low-light-microscope-for-imaging-cellular-bioluminescence-and-radioluminescence
#4
Tae Jin Kim, Silvan Türkcan, Guillem Pratx
Low-light microscopy methods are receiving increased attention as new applications have emerged. One such application is to allow longitudinal imaging of light-sensitive cells with no phototoxicity and no photobleaching of fluorescent biomarkers. Another application is for imaging signals that are inherently dim and undetectable using standard microscopy techniques, such as bioluminescence, chemiluminescence or radioluminescence. In this protocol, we provide instructions on how to build a modular low-light microscope (1-4 d) by coupling two microscope objective lenses, back to back from each other, using standard optomechanical components...
May 2017: Nature Protocols
https://www.readbyqxmd.com/read/28425961/rapid-texture-optimization-of-three-dimensional-urban-model-based-on-oblique-images
#5
Weilong Zhang, Ming Li, Bingxuan Guo, Deren Li, Ge Guo
Seamless texture mapping is one of the key technologies for photorealistic 3D texture reconstruction. In this paper, a method of rapid texture optimization of 3D urban reconstruction based on oblique images is proposed aiming at the existence of texture fragments, seams, and inconsistency of color in urban 3D texture mapping based on low-altitude oblique images. First, we explore implementing radiation correction on the experimental images with a radiation procession algorithm. Then, an efficient occlusion detection algorithm based on OpenGL is proposed according to the mapping relation between the terrain triangular mesh surface and the images to implement the occlusion detection of the visible texture on the triangular facets as well as create a list of visible images...
April 20, 2017: Sensors
https://www.readbyqxmd.com/read/28425431/characterization-of-spatial-distortion-in-a-0-35t-mri-guided-radiotherapy-system
#6
John S Ginn, Nzhde Agazaryan, Minsong Cao, Umar Baharom, Daniel Low, Yingli Yang, Yu Gao, Peng Hu, Percy Lee, James Lamb
Spatial distortion results in image deformation that can degrade accurate targeting and dose calculations in MRI-guided adaptive radiotherapy. The authors present a comprehensive assessment of a 0.35T MRI-guided radiotherapy system's spatial distortion using two commercially-available phantoms with regularly spaced markers. Images of the spatial integrity phantoms were acquired using five clinical protocols on the MRI-guided radiotherapy machine with the radiotherapy gantry positioned at various angles. Software was developed to identify and localize all phantom markers using a template matching approach...
April 20, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28424704/draco-stem-an-automatic-tool-to-generate-high-quality-3d-meshes-of-shoot-apical-meristem-tissue-at-cell-resolution
#7
Guillaume Cerutti, Olivier Ali, Christophe Godin
Context: The shoot apical meristem (SAM), origin of all aerial organs of the plant, is a restricted niche of stem cells whose growth is regulated by a complex network of genetic, hormonal and mechanical interactions. Studying the development of this area at cell level using 3D microscopy time-lapse imaging is a newly emerging key to understand the processes controlling plant morphogenesis. Computational models have been proposed to simulate those mechanisms, however their validation on real-life data is an essential step that requires an adequate representation of the growing tissue to be carried out...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28424090/targeted-endomyocardial-biopsy-guided-by-real-time-cardiovascular-magnetic-resonance
#8
Christina Unterberg-Buchwald, Christian Oliver Ritter, Verena Reupke, Robin Niklas Wilke, Christine Stadelmann, Michael Steinmetz, Andreas Schuster, Gerd Hasenfuß, Joachim Lotz, Martin Uecker
BACKGROUND: Endomyocardial biopsies (EMB) are an important diagnostic tool for myocarditis and other infiltrative cardiac diseases. Routinely, biopsies are obtained under fluoroscopic guidance with a substantial radiation burden. Despite procedural success, there is a large sampling error caused by missing the affected myocardium. Therefore, multiple (>6) biopsies are taken in the clinical setting. In cardiovascular magnetic resonance (CMR), late gadolinium enhancement (LGE) depicts areas of affected myocardium in myocarditis or in other infiltrative cardiomyopathies...
April 19, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28423221/facial-asymmetry-in-head-and-neck-rhabdomyosarcoma-survivors
#9
Reineke A Schoot, Marinka L F Hol, Johannes H M Merks, Michael Suttie, Olga Slater, Marinde van Lennep, Saskia M J Hopman, David Dunaway, Jonathan Syme-Grant, Ludi E Smeele, Koos H Zwinderman, Huib N Caron, Peter Hammond
INTRODUCTION: Radiotherapy is essential for achieving and maintaining local control in head and neck rhabdomyosarcoma (HNRMS) patients. However, radiotherapy may cause outgrowth disturbances of facial bone and soft tissue, resulting in facial asymmetry. The aim of this study was to develop a method to visualize and measure facial asymmetry in HNRMS survivors using three-dimensional (3D) imaging techniques. METHODS: Facial deformity was evaluated in a multidisciplinary clinical assessment of 75 HNRMS survivors, treated with external beam radiotherapy (EBRT, n = 26) or Ablative surgery, MOulage brachytherapy, and REconstruction (AMORE, n = 49)...
April 19, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28422840/case-report-a-female-case-of-isolated-igg4-related-sclerosing-cholangitis-mimicking-cholangiocarcinoma
#10
Jianchun Xiao, Guanqiao Li, Gang Yang, Congwei Jia, Binglu Li
RATIONALE: IgG4-related disease is a newly recognized fibroinflammatory disorder, characterized by tumefactive lesions, storiform fibrosis and IgG4-positive plasma cells infiltration. IgG4-related sclerosing cholangitis (IgG4-SC) is the most common extrapancreatic manifestation of IgG4-related disease, but it is frequently associated with autoimmune pancreatitis(AIP). Only few case was reported to be diagnosed with IgG4-SC in the absence of AIP, with a striking male preponderance. Here we report a female case of isolated IgG4 related sclerosing cholangitis mimicking cholangiocarcinoma...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28422806/improvement-of-image-quality-in-unenhanced-dual-layer-ct-of-the-head-using-virtual-monoenergetic-images-compared-with-polyenergetic-single-energy-ct
#11
Victor Neuhaus, Nuran Abdullayev, Nils Große Hokamp, Gregor Pahn, Christoph Kabbasch, Anastasios Mpotsaris, David Maintz, Jan Borggrefe
OBJECTIVES: The aims of this study were to compare virtual monoenergetic images and polyenergetic images reconstructed from unenhanced dual-layer detector computed tomography (DLCT) of the head and to determine kiloelectron volt levels that optimize image quality, particularly the gray-white matter contrast, and reduce beam hardening artifacts caused by the skull. MATERIALS AND METHODS: Institutional review board approval was obtained. Forty patients that received DLCT were included in this retrospective study; of these patients, 22 were women and 18 were men...
April 19, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28422184/sea-level-proxies-in-holocene-raised-beach-ridge-deposits-greenland-revealed-by-ground-penetrating-radar
#12
Lars Nielsen, Mette Bendixen, Aart Kroon, Mikkel Ulfeldt Hede, Lars B Clemmensen, Ronny Weβling, Bo Elberling
Identification of sea-level proxies is important for reconstruction of past sea-level variation. Methods for reconstructing Holocene relative sea-level curves are crucial for quantification of the impact of Greenland ice thickness variation on global sea level and vertical land movement. Arctic beach ridges constitute important potential archives of sea-level variation. However, their surface morphology may have undergone modification since deposition due to freezing/thawing processes and erosion, and their morphology may therefore not be trustworthy for sea-level reconstruction...
April 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28422075/multisensory-system-for-the-detection-and-localization-of-peripheral-subcutaneous-veins
#13
Roemi Fernández, Manuel Armada
This paper proposes a multisensory system for the detection and localization of peripheral subcutaneous veins, as a first step for achieving automatic robotic insertion of catheters in the near future. The multisensory system is based on the combination of a SWIR (Short-Wave Infrared) camera, a TOF (Time-Of-Flight) camera and a NIR (Near Infrared) lighting source. The associated algorithm consists of two main parts: one devoted to the features extraction from the SWIR image, and another envisaged for the registration of the range data provided by the TOF camera, with the SWIR image and the results of the peripheral veins detection...
April 19, 2017: Sensors
https://www.readbyqxmd.com/read/28421723/clinical-outcomes-of-proton-beam-therapy-for-choroidal-melanoma-at-a-single-institute-in-korea
#14
Tae Wan Kim, Euncheol Choi, Jeonghoon Park, Dong-Ho Shin, Su Kyung Jung, Susie Seok, Kwan Ho Cho, Joo-Young Kim, Dae Yong Kim, Tae Hyun Kim, Yang Kwon Suh, Yeon Joo Kim, Sung Ho Moon
Purpose: This study retrospectively evaluated the clinical outcomes and complications of proton beam therapy (PBT) in a single institution in Korea and quantitatively analyzed the change in tumor volume after PBT using magnetic resonance imaging (MRI). Materials and Methods: Twenty-four treatment-naïve patients who underwent PBT for choroidal melanoma between 2009 and 2015 were reviewed. Dose fractionation was 60-70 CGE over 5 fractions. Orbital MRIs were taken at baseline and 3, 6, and 12 months after PBT and annually thereafter...
April 19, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28420831/enamel-microcracks-in-terms-of-orthodontic-treatment-a-novel-method-for-their-detection-and-evaluation
#15
Irma Dumbryte, Laura Linkeviciene, Tomas Linkevicius, Mangirdas Malinauskas
The study aimed at introducing current available techniques for enamel microcracks (EMCs) detection, and presenting a method for direct quantitative analysis of an individual EMC. Measurements of the detailed EMCs characteristics (location, length, and width) were taken from the reconstructed images of the buccal tooth surface (teeth extracted from two age groups of patients) employing a scanning electron microscopy (SEM) and our derived formulas before and after ceramic brackets removal. Measured parameters of EMCs for younger age group were 2...
April 18, 2017: Dental Materials Journal
https://www.readbyqxmd.com/read/28420788/reconstructing-the-spectrotemporal-modulations-of-real-life-sounds-from-fmri-response-patterns
#16
Roberta Santoro, Michelle Moerel, Federico De Martino, Giancarlo Valente, Kamil Ugurbil, Essa Yacoub, Elia Formisano
Ethological views of brain functioning suggest that sound representations and computations in the auditory neural system are optimized finely to process and discriminate behaviorally relevant acoustic features and sounds (e.g., spectrotemporal modulations in the songs of zebra finches). Here, we show that modeling of neural sound representations in terms of frequency-specific spectrotemporal modulations enables accurate and specific reconstruction of real-life sounds from high-resolution functional magnetic resonance imaging (fMRI) response patterns in the human auditory cortex...
April 18, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28419808/outcomes-after-1-stage-versus-2-stage-revision-anterior-cruciate-ligament-reconstruction
#17
Justin J Mitchell, Jorge Chahla, Chase S Dean, Mark Cinque, Lauren M Matheny, Robert F LaPrade
BACKGROUND: Revision anterior cruciate ligament reconstruction (ACLR) is becoming increasingly common as the number of primary ACLR cases continues to rise. Despite this, there are limited data on the outcomes of revision ACLR and even less information specifically addressing the differences in 1-stage revision reconstruction versus those performed in a 2-stage fashion after primary reconstruction. PURPOSE: To compare the outcomes, patient satisfaction, and failure rates of 1-stage versus 2-stage revision ACLR...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28419804/simultaneous-reconstruction-of-the-medial-and-lateral-collateral-ligaments-for-chronic-combined-ligament-injuries-of-the-ankle
#18
Toshito Yasuda, Hiroaki Shima, Katsunori Mori, Seiya Tsujinaka, Masashi Neo
BACKGROUND: Objective data on chronic injuries of the medial collateral ligament (MCL) of the ankle are scarce. Chronic MCL injuries are frequently associated with lateral collateral ligament (LCL) injuries. For patients with chronic combined MCL and LCL injuries, the authors have performed simultaneous surgery of the 2 ligaments. HYPOTHESIS: Simultaneous surgery of the 2 ligaments may be effectively used to treat chronic combined MCL and LCL injuries. STUDY DESIGN: Case series; Level of evidence, 4...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28419638/a-diffusion-tensor-imaging-tractography-study-in-bipolar-disorder-patients-compared-to-first-degree-relatives-and-healthy-controls
#19
Ananya Mahapatra, Sudhir Kumar Khandelwal, Pratap Sharan, Ajay Garg, N K Mishra
AIM: To compare white matter structural changes in specific tracts by diffusion tensor imaging (DTI) tractography in patients of bipolar disorder I, non-ill first degree relatives of the patients, and healthy controls. METHODS: In a cross sectional study, we studied right-handed subjects consisting of 16 euthymic bipolar disorder I patients, 15 first degree relatives and 15 healthy controls. The anterior thalamic radiation, uncinate fasciculus, corpus callosum, and cingulum bundle were reconstructed by DTI tractography...
April 17, 2017: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28419591/application-of-spin-echoes-in-the-regime-of-weak-dephasing-to-t1-mapping-of-the-lung
#20
Jakob Assländer, Steffen J Glaser, Jürgen Hennig
PURPOSE: This work presents an approach to mapping the entire lung's proton density and T1 within a single breath-hold and analyzes the apparent T1 when exciting with a spin echo generating pulse in comparison to a standard gradient echo acquisition. METHODS: An inversion-recovery SNAPSHOT-FLASH sequence with a stack-of-stars k-space readout with a golden angle increment was modified to use a spin echo generating radiofrequency-pulse for excitation. Data of five volunteers were acquired on a 3T scanner and image reconstruction was performed by an iterative algorithm adopted from MR-Fingerprinting...
April 17, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
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