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Discrete choice experiment

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https://www.readbyqxmd.com/read/27920507/men-s-preferences-for-the-treatment-of-lower-urinary-tract-symptoms-associated-with-benign-prostatic-hyperplasia-a-discrete-choice-experiment
#1
Colette Mankowski, Divine Ikenwilo, Sebastian Heidenreich, Mandy Ryan, Jameel Nazir, Cathy Newman, Verity Watson
OBJECTIVE: To explore and quantify men's preferences and willingness to pay (WTP) for attributes of medications for lower urinary tract symptoms associated with benign prostatic hyperplasia using a discrete choice experiment. SUBJECTS AND METHODS: Men in the UK aged ≥45 years with moderate-to-severe lower urinary tract symptoms/benign prostatic hyperplasia (based on self-reported International Prostate Symptom Score ≥8) were recruited. An online discrete choice experiment survey was administered...
2016: Patient Preference and Adherence
https://www.readbyqxmd.com/read/27917560/is-best-worst-scaling-suitable-for-health-state-valuation-a-comparison-with-discrete-choice-experiments
#2
Nicolas Krucien, Verity Watson, Mandy Ryan
Health utility indices (HUIs) are widely used in economic evaluation. The best-worst scaling (BWS) method is being used to value dimensions of HUIs. However, little is known about the properties of this method. This paper investigates the validity of the BWS method to develop HUI, comparing it to another ordinal valuation method, the discrete choice experiment (DCE). Using a parametric approach, we find a low level of concordance between the two methods, with evidence of preference reversals. BWS responses are subject to decision biases, with significant effects on individuals' preferences...
December 4, 2016: Health Economics
https://www.readbyqxmd.com/read/27905819/mothers-preferences-regarding-new-combination-vaccines-for-their-children-in-japan-2014
#3
Aiko Shono, Masahide Kondo
A number of new vaccines to prevent childhood diseases have been introduced globally over the last few decades. Only four combination vaccines are currently available in Japan, DTaP/sIPV, DTaP, DT, and MR, leading to complex infant vaccine scheduling. This study aims to investigate mothers' preferences with respect to combination vaccines for their children, should new combination vaccines become available that have not yet been launched in Japan or that will be developed in the future. We conducted a web-based, cross-sectional survey of 1,243 mothers who had at least one child between 2 months and 3 years of age...
December 1, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27884193/reorganising-specialist-cancer-surgery-for-the-twenty-first-century-a-mixed-methods-evaluation-respect-21
#4
Naomi J Fulop, Angus I G Ramsay, Cecilia Vindrola-Padros, Michael Aitchison, Ruth J Boaden, Veronica Brinton, Caroline S Clarke, John Hines, Rachael M Hunter, Claire Levermore, Satish B Maddineni, Mariya Melnychuk, Caroline M Moore, Muntzer M Mughal, Catherine Perry, Kathy Pritchard-Jones, David C Shackley, Jonathan Vickers, Stephen Morris
BACKGROUND: There are longstanding recommendations to centralise specialist healthcare services, citing the potential to reduce variations in care and improve patient outcomes. Current activity to centralise specialist cancer surgical services in two areas of England provides an opportunity to study the planning, implementation and outcomes of such changes. London Cancer and Manchester Cancer are centralising specialist surgical pathways for prostate, bladder, renal, and oesophago-gastric cancers, so that these services are provided in fewer hospitals...
November 25, 2016: Implementation Science: IS
https://www.readbyqxmd.com/read/27881284/perceived-risks-contra-benefits-of-using-biosimilar-drugs-in-ulcerative-colitis-discrete-choice-experiment-among-gastroenterologists
#5
Petra Baji, László Gulácsi, Petra A Golovics, Barbara D Lovász, Márta Péntek, Valentin Brodszky, Fanni Rencz, Péter L Lakatos
BACKGROUND: In middle-income countries, access to biological therapy is limited in ulcerative colitis in terms of the number of patients and the length of therapy. Because of their cost advantages, biosimilars have the potential to improve access to therapy, but physicians have concerns toward their use because of the lack of evidence from randomized clinical trials. OBJECTIVES: To explore the preferences of gastroenterologists for biosimilar drugs in ulcerative colitis as well as to compare our results with results of previous studies on gastroenterologists' preferences toward biosimilars...
September 2016: Value in Health Regional Issues
https://www.readbyqxmd.com/read/27873226/is-dimension-order-important-when-valuing-health-states-using-discrete-choice-experiments-including-duration
#6
Brendan Mulhern, Richard Norman, Paula Lorgelly, Emily Lancsar, Julie Ratcliffe, John Brazier, Rosalie Viney
BACKGROUND: Discrete choice experiments with duration (DCETTO) can be used to estimate utility values for preference-based measures, such as the EQ-5D-5L. For self-completion, the health dimensions are presented in a standard order. However, for valuation, this may result in order effects. Thus, it is important to understand whether health state dimension ordering affects values. The aim of this study was to examine the importance of dimension ordering on DCE values using EQ-5D-5L. METHODS: A choice experiment presenting two health profiles and a third immediate death option was developed...
November 21, 2016: PharmacoEconomics
https://www.readbyqxmd.com/read/27853894/determining-preferences-related-to-hiv-counselling-and-testing-services-among-high-school-learners-in-kwazulu-natal-a-discrete-choice-experiment
#7
Michael Strauss, Gavin L George, Bruce D Rhodes
A key strategy of the South African national response to HIV is the scale-up of HIV counselling and testing (HCT) in the 15-49 years age group. The integrated school health policy aims to guide the roll out of youth-friendly health services including the provision of HCT in schools. Using a discrete choice experiment to examine preferences regarding the attributes of HCT service packages, this study identifies barriers to and facilitators of HCT among high school learners. Monetary considerations were found to have the strongest effect of any attribute on choice, whilst confidentiality was found to be a primary concern for learners considering HCT...
November 16, 2016: AIDS and Behavior
https://www.readbyqxmd.com/read/27849124/people-with-dementia-and-carer-preferences-for-home-support-services-in-early-stage-dementia
#8
Helen Chester, Paul Clarkson, Linda Davies, Caroline Sutcliffe, Sue Davies, Alexandra Feast, Jane Hughes, David Challis
OBJECTIVES: To examine people with dementia and carer preferences for home support attributes in early-stage dementia, building on the paucity of evidence in this area. METHOD: Preferences from 44 people with dementia and 103 carers, recruited through memory clinics and an online questionnaire, were assessed with a Discrete Choice Experiment survey, with attributes informed by an evidence synthesis and lay consultation. A conditional logit model was used to estimate preference weights for the attributes within a home support 'package'...
November 16, 2016: Aging & Mental Health
https://www.readbyqxmd.com/read/27846242/understanding-health-workers-job-preferences-to-improve-rural-retention-in-timor-leste-findings-from-a-discrete-choice-experiment
#9
Marc-Francois Smitz, Sophie Witter, Christophe Lemiere, Patrick Hoang-Vu Eozenou, Tomas Lievens, Rashid U Zaman, Kay Engelhardt, Xiaohui Hou
BACKGROUND: Timor-Leste built its health workforce up from extremely low levels after its war of independence, with the assistance of Cuban training, but faces challenges as the first cohorts of doctors will shortly be freed from their contracts with government. Retaining doctors, nurses and midwives in remote areas requires a good understanding of health worker preferences. METHODS: The article reports on a discrete choice experiment (DCE) carried out amongst 441 health workers, including 173 doctors, 150 nurses and 118 midwives...
2016: PloS One
https://www.readbyqxmd.com/read/27843301/examining-patient-preferences-in-the-treatment-of-rheumatoid-arthritis-using-a-discrete-choice-approach
#10
Rieke Alten, Klaus Krüger, Julian Rellecke, Julia Schiffner-Rohe, Olaf Behmer, Guido Schiffhorst, Hans-Dieter Nolting
BACKGROUND: Biological disease-modifying antirheumatic drugs (bDMARDs) used in second-line treatment of rheumatoid arthritis (RA) are administered parenterally. However, so-called targeted synthetic DMARDs (tsDMARDs) - developed more recently - offer alternative (ie, oral) administration forms in second-line treatment. Since bDMARDs and tsDMARDs can be regarded as equal in terms of efficacy, the present study examines whether such characteristics as route of administration drive RA patients' treatment choice...
2016: Patient Preference and Adherence
https://www.readbyqxmd.com/read/27836037/factors-affecting-chinese-broiler-farmers-main-preventive-practices-in-response-to-highly-pathogenic-avian-influenza
#11
Zeying Huang, Di Zeng, Jimin Wang
Preventive practices are highly important in response to highly pathogenic avian influenza (HPAI). As biosecurity guidelines, HPAI vaccination, antiviral medication, farm cleaning and disinfection jointly focus on mitigating the risk of infectious pathogen spread, yet much less is known about the association between broiler farmer's socio-economic characteristics and their adoption decision of these preventive practices. The current study aims to bridge this gap using a nationally representative household survey of 331 Chinese chicken farm owners, among whom the practices are far from fully adopted (only 58% of the farmers adopt all four types)...
November 1, 2016: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/27814714/patient-preferences-for-treatment-of-castration-resistant-prostate-cancer-in-japan-a-discrete-choice-experiment
#12
Hiroji Uemura, Nobuaki Matsubara, Go Kimura, Akito Yamaguchi, Dianne Athene Ledesma, Marco DiBonaventura, Ateesha F Mohamed, Enrique Basurto, Ian McKinnon, Ed Wang, Kristen Concialdi, Aya Narimatsu, Yasuko Aitoku
BACKGROUND: Up to a fifth of patients diagnosed with prostate cancer (PC) will develop castration-resistant prostate cancer (CRPC), which has been associated with a poor prognosis. The aim of this study was to consider the patient perspective as part of the overall treatment decision-making process for CRPC, given that an alignment between patient preference and prescribing has been shown to benefit patient outcomes. This study examines preferences of patients with CRPC in Japan for treatment features associated with treatments like RA-223, abiraterone, and docetaxel and to examine the extent to which treatment preferences may vary between symptomatic and asymptomatic patients...
November 4, 2016: BMC Urology
https://www.readbyqxmd.com/read/27812746/junior-doctors-medical-specialty-and-practice-location-choice-simulating-policies-to-overcome-regional-inequalities
#13
Pedro Ramos, Hélio Alves, Paulo Guimarães, Maria A Ferreira
There are nowadays over 1 million Portuguese who lack a primary care physician. By applying a discrete choice experiment to a large representative sample of Portuguese junior doctors (N = 503) in 2014, we provide an indication that this shortage may be addressed with a careful policy design that mixes pecuniary and non-pecuniary incentives for these junior physicians. According to our simulations, a policy that includes such incentives may increase uptake of general practitioners (GPs) in rural areas from 18% to 30%...
November 3, 2016: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/27804191/patient-and-nurse-preferences-for-implementation-of-bedside-handover-do-they-agree-findings-from-a-discrete-choice-experiment
#14
Jennifer A Whitty, Jean Spinks, Tracey Bucknall, Georgia Tobiano, Wendy Chaboyer
OBJECTIVE: To describe and compare patients' and nurses' preferences for the implementation of bedside handover. DESIGN: Discrete choice experiment describing handover choices using six characteristics: whether the patient is invited to participate; whether a family member/carer/friend is invited; the number of nurses present; the level of patient involvement; the information content; and privacy. SETTING: Two Australian hospitals. PARTICIPANTS: Adult patients (n=401) and nurses (n=200) recruited from medical wards...
November 2, 2016: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/27802453/determining-cancer-survivors-preferences-to-inform-new-models-of-follow-up-care
#15
Peter Murchie, Patricia F Norwood, Marta Pietrucin-Materek, Terry Porteous, Philip C Hannaford, Mandy Ryan
BACKGROUND: Specialist-led cancer follow-up is becoming increasingly expensive and is failing to meet many survivors' needs. Alternative models informed by survivors' preferences are urgently needed. It is unknown if follow-up preferences differ by cancer type. We conducted the first study to assess British cancer survivors' follow-up preferences, and the first anywhere to compare the preferences of survivors from different cancers. METHODS: A discrete choice experiment questionnaire was mailed to 1201 adults in Northeast Scotland surviving melanoma, breast, prostate or colorectal cancer...
December 6, 2016: British Journal of Cancer
https://www.readbyqxmd.com/read/27799749/physician-and-patient-benefit-risk-preferences-from-two-randomized-long-acting-injectable-antipsychotic-trials
#16
Eva G Katz, Brett Hauber, Srihari Gopal, Angie Fairchild, Amy Pugh, Rachel B Weinstein, Bennett S Levitan
PURPOSE: To quantify clinical trial participants' and investigators' judgments with respect to the relative importance of efficacy and safety attributes of antipsychotic treatments for schizophrenia, and to assess the impact of formulation and adherence. METHODS: Discrete-choice experiment surveys were completed by patients with schizophrenia and physician investigators participating in two phase-3 clinical trials of paliperidone palmitate 3-month long-acting injectable (LAI) antipsychotic...
2016: Patient Preference and Adherence
https://www.readbyqxmd.com/read/27796664/a-discrete-choice-experiment-to-explore-patients-willingness-to-risk-disease-relapse-from-treatment-withdrawal-in-psoriatic-arthritis
#17
Claire Rothery, Laura Bojke, Gerry Richardson, Chris Bojke, Anna Moverley, Laura Coates, Liz Thorp, Robin Waxman, Philip Helliwell
The objective of this study is to assess patient preferences for treatment-related benefits and risk of disease relapse in the management of low disease states of psoriatic arthritis (PsA). Focus groups with patients and a literature review were undertaken to determine the characteristics of treatment and symptoms of PsA important to patients. Patient preferences were assessed using a discrete choice experiment which compared hypothetical treatment profiles of the risk and benefits of treatment withdrawal. The risk outcome included increased risk of disease relapse, while benefit outcomes included reduced sickness/nausea from medication and changes in health-related quality of life...
December 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/27790801/are-health-state-valuations-from-the-general-public-biased-a-test-of-health-state-reference-dependency-using-self-assessed-health-and-an-efficient-discrete-choice-experiment
#18
Marcel F Jonker, Arthur E Attema, Bas Donkers, Elly A Stolk, Matthijs M Versteegh
Health state valuations of patients and non-patients are not the same, whereas health state values obtained from general population samples are a weighted average of both. The latter constitutes an often-overlooked source of bias. This study investigates the resulting bias and tests for the impact of reference dependency on health state valuations using an efficient discrete choice experiment administered to a Dutch nationally representative sample of 788 respondents. A Bayesian discrete choice experiment design consisting of eight sets of 24 (matched pairwise) choice tasks was developed, with each set providing full identification of the included parameters...
October 27, 2016: Health Economics
https://www.readbyqxmd.com/read/27783657/non-market-values-in-a-cost-benefit-world-evidence-from-a-choice-experiment
#19
Florian V Eppink, Matthew Winden, Will C C Wright, Suzie Greenhalgh
In support of natural resource and ecosystem service policy, monetary value estimates are often presented to decision makers along with other types of information. There is some evidence that, presented with such 'mixed' information, people prioritise monetary over non-monetary information. We conduct a discrete choice experiment among New Zealand decision makers in which we manipulate the information presented to participants. We find that providing explicit monetary information strengthens the pursuit of economic benefits as well as the avoidance of environmental damage...
2016: PloS One
https://www.readbyqxmd.com/read/27771167/treatment-preferences-of-advanced-ovarian-cancer-patients-for-adding-bevacizumab-to-first-line-therapy
#20
Jung-Yun Lee, Kyunghoon Kim, Yun Shin Lee, Hyo Young Kim, Eun Ji Nam, Sunghoon Kim, Sang Wun Kim, Jae Weon Kim, Young Tae Kim
BACKGROUND: The GOG-218 and ICON-7 studies recently showed that adding bevacizumab to first-line therapy for patients with advanced ovarian cancer increased progression-free survival. However, the high cost and long treatment duration prevents the incorporation of bevacizumab in practice. The aim of this study was to explore and quantify patients' preferences for adding bevacizumab to first-line therapy. METHODS: A discrete choice experiment (DCE) and trade-off question were designed and distributed to 102 ovarian cancer patients...
December 2016: Gynecologic Oncology
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