keyword
MENU ▼
Read by QxMD icon Read
search

burn wound

keyword
https://www.readbyqxmd.com/read/29691339/outbreak-of-invasive-wound-mucormycosis-in-a-burn-unit-due-to-multiple-strains-of-mucor-circinelloides-f-circinelloides-resolved-by-whole-genome-sequencing
#1
Dea Garcia-Hermoso, Alexis Criscuolo, Soo Chan Lee, Matthieu Legrand, Marc Chaouat, Blandine Denis, Matthieu Lafaurie, Martine Rouveau, Charles Soler, Jean-Vivien Schaal, Maurice Mimoun, Alexandre Mebazaa, Joseph Heitman, Françoise Dromer, Sylvain Brisse, Stéphane Bretagne, Alexandre Alanio
Mucorales are ubiquitous environmental molds responsible for mucormycosis in diabetic, immunocompromised, and severely burned patients. Small outbreaks of invasive wound mucormycosis (IWM) have already been reported in burn units without extensive microbiological investigations. We faced an outbreak of IWM in our center and investigated the clinical isolates with whole-genome sequencing (WGS) analysis. We analyzed M. circinelloides isolates from patients in our burn unit (BU1, Hôpital Saint-Louis, Paris, France) together with nonoutbreak isolates from Burn Unit 2 (BU2, Paris area) and from France over a 2-year period (2013 to 2015)...
April 24, 2018: MBio
https://www.readbyqxmd.com/read/29690741/-antiseptic-effect-of-compound-lysostaphin-disinfectant-and-its-preventive-effect-on-infection-of-artificial-dermis-after-graft-on-full-thickness-skin-defect-wound-in-rats
#2
J Jin, H Zhou, Z C Cui, L Wang, P F Luo, S Z Ji, X Y Hu, B Ma, G Y Wang, S H Zhu, Z F Xia
Objective: To study the antiseptic effect of compound lysostaphin disinfectant and its preventive effect on infection of artificial dermis after graft on full-thickness skin defect wound in rats. Methods: (1) Each one standard strain of Klebsiella pneumoniae, Acinetobacter baumannii, and Staphylococcus aureus were selected. Each 20 clinical strains of Klebsiella pneumoniae, Acinetobacter baumannii, and Staphylococcus aureus were collected from those isolated from wound exudates of burn patients hospitalized in our wards from January 2014 to December 2016 according to the random number table...
April 20, 2018: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/29683361/human-recombinant-epidermal-growth-factor-in-skin-lesions-77-cases-in-epitelizando-project
#3
Jordi Esquirol-Caussa, Elisabeth Herrero-Vila
OBJECTIVE: To analyze compounded recombinant human Epidermal Growth Factor (rhEGF) effectiveness on skin lesions through a case series. DESIGN: Multicentric series of skin lesions treated with topical recombinant human Epidermal Growth Factor. SITE: Patients from 56 different health professionals, three different countries, two recruitment years. PARTICIPANTS: 77 patients with skin lesions, mean age 63.15 years (min = 18, max = 95); 53...
April 23, 2018: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29681237/antimicrobial-peptide-delivery-an-emerging-therapeutic-for-the-treatment-of-burn-and-wounds
#4
Ankit Javia, Jitendra Amrutiya, Rohan Lalani, Vivek Patel, Priyanka Bhatt, Ambikanandan Misra
The management of wounds and burns is becoming difficult using conventional therapeutics available due to resistance development by microbes. Therefore, there is an utmost need to develop therapeutic alternatives to these agents. Antimicrobial peptides have emerged as a novel class of agents for the effective management of wounds and burns due to their potent nature along with minimal chances of resistance development against them. This article focuses on highlighting the importance of these antimicrobial peptides among the various therapeutic alternatives for burns and wounds...
May 2018: Therapeutic Delivery
https://www.readbyqxmd.com/read/29675982/probing-endogenous-collagen-by-laser-induced-autofluorescence-in-burn-wound-biopsies-a-pilot-study
#5
Vijendra Prabhu, Anusha Acharya, Bola Sadashiva Satish Rao, Bharath Rathnakar, Pramod Kumar, Vasudeva Guddattu, Krishna Kishore Mahato
The focus of the current study was to interrogate the predictive potential of laser-induced autofluorescence (LIAF) by objectively assessing collagen synthesis in burn wound granulation tissues ex vivo. Prior grafting, granulation tissues (20 samples) following burn injury were collected from 17 subjects of age range 18- 60 years with patient/donor consent and the corresponding autofluorescence spectra were recorded at 325 nm He-Cd laser (≈ 2 mW) excitations. The resulting endogenous collagen intensity from the above tissue samples was computed by normalizing the NADH levels...
April 19, 2018: Journal of Biophotonics
https://www.readbyqxmd.com/read/29675321/burn-injured-tissue-detection-for-debridement-surgery-through-the-combination-of-non-invasive-optical-imaging-techniques
#6
Juan Heredia-Juesas, Jeffrey E Thatcher, Yang Lu, John J Squiers, Darlene King, Wensheng Fan, J Michael DiMaio, Jose A Martinez-Lorenzo
The process of burn debridement is a challenging technique requiring significant skills to identify the regions that need excision and their appropriate excision depths. In order to assist surgeons, a machine learning tool is being developed to provide a quantitative assessment of burn-injured tissue. This paper presents three non-invasive optical imaging techniques capable of distinguishing four kinds of tissue-healthy skin, viable wound bed, shallow burn, and deep burn-during serial burn debridement in a porcine model...
April 1, 2018: Biomedical Optics Express
https://www.readbyqxmd.com/read/29673562/candida-tropicalis-burn-wound-sepsis-a-series-of-histopathology-confirmed-cases
#7
Chunjie Fan, Qingfen Tian, Guobao Huang, Lei Zhang, Qiuhe Wu, Keyan Zhang
Fungal infection in severely burned patients is a serious problem due to various factors, such as the extensive application of antibiotics. In this study, we report on the course of severely burned patients with Candida tropicalis burn wound sepsis. Five such cases were reviewed. The patients were treated with itraconazole intravenously and simultaneous antibiotics to prevent bacterial infections. In addition, dermabrasion was used to excise the eschar and the wound surface was covered immediately with dermatoplasty...
April 16, 2018: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/29673408/long-term-scar-quality-after-hydrosurgical-versus-conventional-debridement-of-deep-dermal-burns-hycon-trial-study-protocol-for-a-randomized-controlled-trial
#8
Catherine M Legemate, Harold Goei, Esther Middelkoop, Irma M M H Oen, Tim H J Nijhuis, Kelly A A Kwa, Paul P M van Zuijlen, Gerard I J M Beerthuizen, Marianne K Nieuwenhuis, Margriet E van Baar, Cornelis H van der Vlies
BACKGROUND: Deep dermal burns require tangential excision of non-viable tissue and skin grafting to improve wound healing and burn-scar quality. Tangential excision is conventionally performed with a knife, but during the last decade hydrosurgery has become popular as a new tool for tangential excision. Hydrosurgery is generally thought to be a more precise and controlled manner of burn debridement leading to preservation of viable tissue and, therefore, better scar quality. Although scar quality is considered to be one of the most important outcomes in burn surgery today, no randomized controlled study has compared the effect of these two common treatment modalities with scar quality as a primary outcome...
April 19, 2018: Trials
https://www.readbyqxmd.com/read/29668985/efficacy-of-a-gel-containing-polihexanide-and-betaine-in-deep-partial-and-full-thickness-burns-requiring-split-thickness-skin-grafts-a-non-comparative-clinical-study
#9
Jurij Kiefer, Kamran Harati, Wibke Müller-Seubert, Sebastian Fischer, Benjamin Ziegler, Björn Behr, Jochen Gille, Ulrich Kneser, Marcus Lehnhardt, Adrien Daigeler, Adrian Dragu
Background: Despite overall advances in burn therapy, wound infection remains one of the leading causes of morbidity and mortality in patients with severe burn injuries. This prospective, multicenter, non-comparative clinical trial was conducted to assess the efficacy and safety of Prontosan® Wound Gel X (PWX), a gel containing polihexanide and betaine, for moistening and cleansing in deep tissue burn wounds requiring split-thickness skin grafting. Methods: Patients with deep partial or full thickness burn wounds requiring split-thickness skin grafting were treated with the gel to evaluate its tolerability and safety as well as graft take and the healing of the skin graft...
April 14, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/29665678/lectin-functionalized-composite-hydrogels-for-capture-and-killing-of-carbapenem-resistant-pseudomonas-aeruginosa
#10
Nicholas Bodenberger, Dennis Kubiczek, Daniel Halbgebauer, Vittoria Rimola, Sebastian Wiese, Daniel Mayer, Armando Alexei Rodr Iacute Guez Alfonso, Ludger Ständker, Steffen Stenger, Frank Rosenau
Infections with multi-resistant pathogens are a leading cause for mortality worldwide. Just recently, the world health organization (WHO) increased the threat rating for multi-resistant Pseudomonas aeruginosa to the highest possible level. With this background it is crucial to develop novel materials and procedures in the fight against multi-resistant pathogens. In this study we present a novel antimicrobial material, which could find applications as a wound dressing or antimicrobial coating. Lectins are multivalent sugar-binding proteins, which can be found in a variety of plants and bacteria, where they are associated with biofilm formation...
April 17, 2018: Biomacromolecules
https://www.readbyqxmd.com/read/29664823/incidence-of-cellulitis-in-lower-extremity-burns-6-year-analysis
#11
Joseph N Batac, Roger L Simpson, Catherine J Sinnott, Michael P Catanzaro, Laurence T Glickman
INTRODUCTION: Patients with burn wounds of the lower extremities are at increased risk of developing cellulitis. The probability of developing burn-associated cellulitis is presumed to be correlated with a medical history of diabetes, the etiology of the burn, delay in hospitalization of the patient during their initial presentation, and depth of the burn itself. This study aims to identify factors that place patients at increased risk for developing lower extremity burn wound cellulitis...
April 17, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29664017/specialized-fibroblast-differentiated-states-underlie-scar-formation-in-the-infarcted-mouse-heart
#12
Xing Fu, Hadi Khalil, Onur Kanisicak, Justin G Boyer, Ronald J Vagnozzi, Bryan D Maliken, Michelle A Sargent, Vikram Prasad, Iñigo Valiente-Alandi, Burns C Blaxall, Jeffery D Molkentin
Fibroblasts are a dynamic cell type that achieve selective differentiated states to mediate acute wound healing and long-term tissue remodeling with scarring. With myocardial infarction injury, cardiomyocytes are replaced by secreted extracellular matrix proteins produced by proliferating and differentiating fibroblasts. Here, we employed 3 different mouse lineage-tracing models and stage-specific gene profiling to phenotypically analyze and classify resident cardiac fibroblast dynamics during myocardial infarction injury and stable scar formation...
April 16, 2018: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/29663582/the-skin-microbiome-of-wound-scars-and-unaffected-skin-in-patients-with-moderate-to-severe-burns-in-the-subacute-phase
#13
Su-Hsun Liu, Yhu-Chering Huang, Leslie Y Chen, Shu-Chuan Yu, Hsiao-Yun Yu, Shiow-Shuh Chuang
Although studies on skin microbiome of acute and chronic wounds abound, evidence on newly-built microbial communities of subacute wounds remains scant. To characterize the skin microbiome of recently-healed (scarred) burn wounds in relation to unaffected skin surfaces, we collected weekly swabs from patients with moderate to severe burns in the 3rd postburn month for 4 weeks in 2015. We performed skin type (moist, dry, and oily)-matched comparisons within six burn patients (43 pairs of swabs) and with 13 skin-healthy, control patients (22 pairs of samples) using 16S ribosomal RNA (rRNA) gene sequencing results...
April 17, 2018: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/29661554/effect-of-skin-graft-thickness-on-scar-development-in-a-porcine-burn-model
#14
Danielle M DeBruler, Britani N Blackstone, Kevin L McFarland, Molly E Baumann, Dorothy M Supp, J Kevin Bailey, Heather M Powell
Animal models provide a way to investigate scar therapies in a controlled environment. It is necessary to produce uniform, reproducible scars with high anatomic and biologic similarity to human scars to better evaluate the efficacy of treatment strategies and to develop new treatments. In this study, scar development and maturation were assessed in a porcine full-thickness burn model with immediate excision and split-thickness autograft coverage. Red Duroc pigs were treated with split-thickness autografts of varying thickness: 0...
April 13, 2018: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29661552/skin-banking-at-a-regional-burns-centre-the-way-forward
#15
Sunil Manohar Keswani, Mukesh Gopinath Mishra, Shilpa Karnik, Shruti Dutta, Mamata Mishra, Sangita Panda, Reshmi Varghese, Tanvi Virkar, Vaishna Upendran
In India approximately 1 million people get burnt every year and most of them are from the lower or middle income strata. Therefore it is obligatory to find out an economic way of treatment for the affected populace. Since use of human skin allograft is the gold standard for the treatment of burn wound, in-house skin banking for a burn unit hospital is prerequisite to make the treatment procedure affordable. Although, there was one skin bank at India till 2009, but it was difficult for a single bank to cover the entire country's need...
April 13, 2018: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29659947/pediatric-thoracic-trauma-in-iraq-and-afghanistan
#16
Ryan J Keneally, Cynthia H Shields, Albert Hsu, Howard I Prior, Kevin M Creamer
Introduction: The objective of this study is to review available data on pediatric thoracic trauma seen at U.S. military treatment facilities in Iraq and Afghanistan and describe the scope of injuries, patterns seen, and associated mortality. The results were compared with adults injured in Iraq and Afghanistan and other reports of pediatric thoracic trauma in the literature. Materials and Methods: The investigators received approval from the Uniformed Services University of the Health Sciences' institutional review board before the study...
April 6, 2018: Military Medicine
https://www.readbyqxmd.com/read/29656662/beneficial-effects-of-salvia-miltiorrhiza-in-the-healing-of-burn-wounds-an-experimental-study-in-rats
#17
Fatih Irmak, Sevgi Kurt Yazar, Serhat Selami Şirvan, Merdan Serin, Ayşim Özağarı, Ayşin Karasoy Yeşilada
INTRODUCTION: Burn healing is a complicated process and very few treatments can positively alter its effects. The aim of this study was to investigate the effects Salvia miltiorrhiza (SM -Danshen), a traditional Chinese medicine, on burn wound healing. MATERIAL AND METHODS: Twenty rats were included in this study and divided into two groups. 3 × 2 cm wide burn areas were created in the dorsal skin of all the animals with thermal contact. Intraoral 1 ml/day saline and 1 g/kg/day SM were given in control and experiment groups, respectively...
April 14, 2018: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/29655989/in-vivo-migration-of-mesenchymal-stem-cells-to-burn-injury-sites-and-their-therapeutic-effects-in-a-living-mouse-model
#18
Eun Jung Oh, Ho Won Lee, Senthilkumar Kalimuthu, Tae Jung Kim, Hyun Mi Kim, Se Hwan Baek, Liya Zhu, Ji Min Oh, Seung Hyun Son, Ho Yun Chung, Byeong-Cheol Ahn
Mesenchymal stem cell (MSC)-based therapy has emerged as a promising therapeutic strategy for tissue regeneration and repair. In this study, we non-invasively monitored the tracking of MSCs toward burn injury sites using MSCs expressing firefly luciferase (Fluc) gene in living mice, and evaluated the effects of the MSCs at the injury site. Murine MSCs co-expressing Fluc and green fluorescent protein (GFP) were established using a retroviral system (referred to as MSC/Fluc). To evaluate the ability of MSC migration toward burn injury sites, cutaneous burn injury was induced in the dorsal skin of mice...
April 12, 2018: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/29651952/special-traumatized-populations-burns-and-hypothermia
#19
Shruti Mehrotra, Amita Misir
It is important for physicians treating children to be aware of unique presentation that require expertise and knowledge. Two areas of importance when caring for traumatized children are Thermal Burn Injuries, and Hypothermia. Burns commonly result in morbidity in children; as such, the appropriate identification of the severity of the burn and appropriate management are integral to minimize the complications of burns during the acute phase. Attention to proper fluid management is paramount. Knowledge of types of solutions to use during Burn treatment is important...
April 11, 2018: Current Pediatric Reviews
https://www.readbyqxmd.com/read/29651853/oleogel-s10-to-accelerate-healing-of-donor-sites-monocentric-results-of-phase-iii-clinical-trial
#20
B Lipový, M Fiamoli, R Mager, Z Jelínková, J Jarkovský, Z Chaloupková, J Holoubek, I Suchánek, P Brychta
MATERIAL AND METHODS: Oleogel-S10, an ointment containing betulin-rich triterpene dry extract from birch bark was tested in an open, blindly evaluated, prospective, controlled, randomized multicentre study to improve wound healing in donor sites. The primary endpoint was time to wound closure, and secondary endpoints were scar related measurements at the time of wound closure, and 3 and 12 months after wound closure (POSAS, laser speckle contrast analysis, viscoelastic analysis). RESULTS: We report the results from a single centre (Department of Burns and Reconstructive Surgery, University Hospital Brno) of this phase III clinical trial...
2018: Acta Chirurgiae Plasticae
keyword
keyword
75123
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"