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https://www.readbyqxmd.com/read/28911335/mammary-phyllodes-tumor-with-six-episodes-of-a-relapse-a-case-report
#1
Nozomi Iimori, Shinichiro Kashiwagi, Tetsuro Ishikawa, Hidemi Kawajiri, Tsutomu Takashima, Masahiko Ohsawa, Kosei Hirakawa, Masaichi Ohira
BACKGROUND: Phyllodes tumor is a rare breast mass. Most phyllodes tumors are benign, but occasionally some show malignancy. Even if the tumors are benign, they can easily show recurrence. CASE PRESENTATION: We report a case of a 48-year-old Asian woman, who had previously undergone a tumorectomy of her left breast 12 years before, with a pathological diagnosis of fibroadenoma. Five years after the initial tumorectomy, the patient presented with an abnormally enlarged left breast...
September 15, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28890755/architectural-patterns-for-differential-diagnosis-of-proliferative-breast-lesions-from-histopathological-images
#2
L Nguyen, A B Tosun, J L Fine, D L Taylor, S C Chennubhotla
The differential diagnosis of proliferative breast lesions, benign usual ductal hyperplasia (UDH) versus malignant ductal carcinoma in situ (DCIS) is challenging. This involves a pathologist examining histopathologic sections of a biopsy using a light microscope, evaluating tissue structures for their architecture or size, and assessing individual cell nuclei for their morphology. Imposing diagnostic boundaries on features that otherwise exist on a continuum going from benign to atypia to malignant is a challenge...
April 2017: Proceedings of the IEEE International Symposium on Biomedical Imaging: from Nano to Macro
https://www.readbyqxmd.com/read/28887010/improved-performance-of-adjunctive-ultrasonography-after-mammography-screening-for-breast-cancer-among-chinese-females
#3
Henglei Dong, Yubei Huang, Fengju Song, Hongji Dai, Peifang Liu, Ying Zhu, Peishan Wang, Jiali Han, Xishan Hao, Kexin Chen
INTRODUCTION: Until now, no studies have investigated whether women other than those with dense breasts are suitable for adjunctive ultrasonography after negative mammography, and investigated whether all women with negative mammography are suitable for adjunctive ultrasonography. METHODS: Based on the Multi-modality Independent Screening Trial in China, a total of 31,918 women aged 45 to 65 years underwent both ultrasonography and mammography. Physicians performed ultrasonography and mammography separately and were blinded to each other's findings until their interpretations had been recorded...
August 15, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28876633/the-rates-and-risk-factors-for-local-recurrence-of-phyllodes-tumours-in-a-south-african-population
#4
J Spinks, K Fearnhead, S Rayne
BACKGROUND: Phyllodes tumours are rare fibroepithelial neoplasms of the breast. The dilemma with phyllodes tumours is their tendency to local recurrence. METHOD: We retrospectively assessed all histological reports of patients diagnosed with a phyllodes tumour after surgery at the University of the Witwatersrand NHLS (National Health Laboratory Service) Anatomical Pathology Laboratories, Johannesburg, South Africa from 1 January 2005 to 30 June 2016. Clinical and histological parameters were analysed...
June 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28876629/clinical-breast-examination-screening-by-trained-laywomen-in-malawi-integrated-with-other-health-services
#5
L Gutnik, C Lee, J Msosa
BACKGROUND: Breast cancer awareness and early detection are limited in Sub-Saharan Africa. Resource limitations make screening mammography or clinical breast examination (CBE) by physicians or nurses impractical in many settings. METHOD: Four laywomen were trained to deliver breast cancer educational talks and conduct CBE. After training, screening was implemented in diverse urban health clinics. Eligible women were 30 years old, with no prior breast cancer or breast surgery, and clinic attendance for reasons other than a breast concern...
June 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28876592/uptake-and-performance-of-clinical-breast-exam-screening-by-trained-laywomen-in-malawi
#6
L Gutnik, C Lee, V Msosa
BACKGROUND: Breast cancer awareness and early detection are limited in sub-saharan Africa. Resource limitations make screening mammography or clinical breast examination (CBE) by physicians or nurses impractical in many settings. We aimed to assess feasibility and performance of CBE by laywomen in urban health clinics. METHOD: Four laywomen were trained to deliver breast cancer educational talks and conduct CBE. Eligible women were 30 years, with no prior breast cancer or breast surgery, and clinic attendance for reasons other than a breast concern...
September 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28867444/use-of-breast-magnetic-resonance-imaging-and-ultrasonography-for-identifying-nonpalpable-axillae-metastases-in-newly-diagnosed-breast-cancer-patients
#7
Juan Zhou, Feng-Juan Guo, Xiao-Peng Hao, Cui-Jing Chen, Ze-Fei Jiang, Gong-Jie Li
BACKGROUND: The metastasis of axillary lymph node (ALNs) is a critical step in the initial cancer staging of newly diagnosed breast cancer (BC) patients. Various imaging modalities can enhance the sensitivity of clinical examination in assessing the ALN status. PATIENTS AND METHODS: We enrolled 135 patients with BC, confirmed via histopathology, including 4 bilateral BC cases. A total of 139 ipsilateral ALNs adjacent to the breast lesion were examined via physical examination, ultrasonography (US), and magnetic resonance imaging (MRI); of these, 100 were nonpalpable ALNs, as determined by experienced breast surgeons and physicians...
August 9, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28862025/freehand-3t-mr-guided-vacuum-assisted-breast-biopsy-vab-a-five-year-experience
#8
Licia Gristina, Giuseppe Rescinito, Alessandro Garlaschi, Simona Tosto, Luca Cevasco, Massimo Calabrese
Background Magnetic resonance (MR) permits the detection of some malignant lesions that cannot be identified with mammography or ultrasonography. The characterization of these MR-only detectable lesions often requires a biopsy. Purpose To evaluate the technique, the feasibility and the accuracy of freehand 3T MR-guided VAB for the characterization of suspicious, MR-only detectable lesions and to compare VAB results with surgical pathology and follow-up imaging results. Material and Methods During 2010-2015, 118 women who were referred for MR-guided VAB were retrospectively reviewed...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28859252/open-access-database-of-raw-ultrasonic-signals-acquired-from-malignant-and-benign-breast-lesions
#9
Hanna Piotrzkowska-Wróblewska, Katarzyna Dobruch-Sobczak, Michał Byra, Andrzej Nowicki
PURPOSE: The aim of this paper is to provide access to a database consisting of the raw radio-frequency ultrasonic echoes acquired from malignant and benign breast lesions. The database is freely available for study and signal analysis. ACQUISITION AND VALIDATION METHODS: The ultrasonic radio-frequency echoes were recorded from breast focal lesions of patients of the Institute of Oncology in Warsaw. The data were collected between 11/2013 and 10/2015. Patients were examined by a radiologist with 18 years' experience in the ultrasonic examination of breast lesions...
August 31, 2017: Medical Physics
https://www.readbyqxmd.com/read/28845840/a-clinical-approach-to-benign-breast-lesions-in-female-adolescents
#10
Heba Elsedfy
The female breast undergoes two phases of growth and differentiation. The first occurs during fetal life and results in the formation of simple branched ducts, which are able to respond to the hormonal stimuli of maternal origin. The second period of growth occurs at puberty, when the ducts elongate, divide, and form terminal duct lobular units. Breast pathology during adolescence is usually benign and therefore management has to be mostly conservative. Familiarity with the spectrum of breast pathology in this age group is essential...
August 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/28844465/b-mode-ultrasound-combined-with-color-doppler-and-strain-elastography-in-the-diagnosis-of-non-mass-breast-lesions-a-prospective-study
#11
Lujing Li, Xinchuan Zhou, Xinbao Zhao, Shaoyun Hao, Jiyi Yao, Wenjing Zhong, Hui Zhi
Non-mass breast lesions on ultrasound (US) are areas without an associated mass. The purpose of this study was to evaluate whether combining B-mode US with color Doppler US and strain elastography (SE) improves US differentiation between benign and malignant non-mass breast lesions and the decision for biopsy. In this prospective study, three different radiologists analyzed the US images of 77 non-mass lesions independently and recorded Breast Imaging Reporting and Data System (BI-RADS) categories for four data sets...
August 24, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28835335/the-positive-outcome-of-mri-guided-vacuum-assisted-core-needle-breast-biopsies-is-not-influenced-by-a-prior-negative-targeted-second-look-ultrasound
#12
Romuald Ferré, Shaza AlSharif, Ann Aldis, Benoît G Mesurolle
PURPOSE: The study sought to investigate the outcome of breast magnetic resonance-guided biopsies as a function of the indication for magnetic resonance imaging (MRI), the MRI features of the lesions, and the performance or not of a targeted second-look ultrasound (SLUS) prior breast MRI-guided biopsy. METHODS: We identified 158 women with MRI-detected breast lesions scheduled for MRI-guided biopsy (2007-2013). Patient demographics, performance of targeted SLUS, imaging characteristics, and subsequent pathology results were reviewed...
August 21, 2017: Canadian Association of Radiologists Journal, Journal L'Association Canadienne des Radiologistes
https://www.readbyqxmd.com/read/28834447/revisiting-nonmass-enhancement-in-breast-mri-analysis-of-outcomes-and-follow-up-using-the-updated-bi-rads-atlas
#13
Sona A Chikarmane, Aya Y Michaels, Catherine S Giess
OBJECTIVE: The purpose of this study is to assess the frequency of reclassification of nonmass enhancement (NME) as background parenchymal enhancement (BPE) and to determine positive predictive values (PPVs) of NME descriptors using the revised BI-RADS atlas. MATERIALS AND METHODS: A retrospective review of our institution's MRI database from January 1, 2009, through March 30, 2012, identified 6220 contrast-enhanced breast MRI examinations. All findings prospectively assessed as NME and rated as BI-RADS categories 3, 4, and 5 (n = 386) were rereviewed in consensus by two radiologists who were blinded to pathologic findings with the fifth edition of the BI-RADS lexicon...
August 23, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28830847/lesion-characteristics-histopathologic-results-and-follow-up-of-breast-lesions-after-mri-guided-biopsy
#14
Füsun Taşkın, Aykut Soyder, Ahmet Tanyeri, Veli Süha Öztürk, Alparslan Ünsal
PURPOSE: We aimed to assess the effectiveness of magnetic resonance imaging (MRI)-guided vacuum assisted breast biopsy (VABB), evaluate and compare the characteristics and histopathologic findings of lesions and overview the follow-up results of benign lesions. METHODS: MRI findings and histopathologic results of breast lesions biopsied by MRI-guided VABB between 2013 and 2016 were retrospectively analyzed. MRI findings closely related with malignancy were investigated in particular...
August 23, 2017: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/28822394/the-clinical-utility-and-cost-of-postoperative-mammography-completed-within-one-year-of-breast-conserving-therapy-is-it-worth-it
#15
Ahkeel Allen, Allison Cauthen, Justin Vaughan, Paul Dale
Breast conserving therapy (BCT), lumpectomy followed by radiotherapy, is an effective treatment for a majority of breast cancers. According to the National Comprehensive Cancer Network, mammographic imaging should be completed at least six months after completion of radiation. This study evaluates the clinical significance and financial cost of postoperative breast imaging within one year of BCT. Patients treated with BCT between 2014 and 2016 at an academic center were identified retrospectively. The medical records were reviewed to identify the timing and type of the first imaging study after BCT...
August 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28815201/benign-papilloma-of-the-breast
#16
Moshe Sadofsky
The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and Processes, Organ System Pathology, and Diagnostic Medicine and Therapeutic Pathology. For additional information, and a full list of learning objectives for all three competencies, see http://journals.sagepub.com/doi/10.1177/2374289517715040.
January 2017: Acad Pathol
https://www.readbyqxmd.com/read/28804937/breast-tumor-classification-based-on-a-computerized-breast-imaging-reporting-and-data-system-feature-system
#17
Mengyun Qiao, Yuzhou Hu, Yi Guo, Yuanyuan Wang, Jinhua Yu
OBJECTIVES: This work focused on extracting novel and validated digital high-throughput features to present a detailed and comprehensive description of the American College of Radiology Breast Imaging Reporting and Data System (BI-RADS) with the goal of improving the accuracy of ultrasound breast cancer diagnosis. METHODS: First, the phase congruency approach was used to segment the tumors automatically. Second, high-throughput features were designed and extracted on the basis of each BI-RADS category...
August 14, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28801296/-efficacy-of-ultrasound-guided-vacuum-assisted-mammotome-excision-for-management-of-benign-breast-diseases-analysis-of-1267-cases
#18
Shu Liu, Jia-Li Zou, Fu-Lin Zhou, Yan-Man Fang
OBJECTIVE: To assess the clinical value of ultrasound-guided vacuum-assisted Mammotome (MMT) system for surgical resection of benign breast disease. METHODS: This retrospective study was conducted among 1267 patients who underwent minimally invasive surgery with ultrasound-guided MMT system for benign breast disease at our center between January, 2009 and January, 2014. The resection rate, incidence of complication, recurrence rate, patients' satisfaction, clinical follow-up results and risk factors were analyzed...
August 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28796549/association-of-brca-mutation-types-imaging-features-and-pathologic-findings-in-patients-with-breast-cancer-with-brca1-and-brca2-mutations
#19
Su Min Ha, Eun Young Chae, Joo Hee Cha, Hak Hee Kim, Hee Jung Shin, Woo Jung Choi
OBJECTIVE: The purpose of this study is to retrospectively evaluate the relationships between the BRCA mutation types, imaging features, and pathologic findings of breast cancers in BRCA1 and BRCA2 mutation carriers. MATERIALS AND METHODS: We identified patients with breast cancer with BRCA gene mutations from January 2000 to December 2014. After excluding patients who underwent lesion excision before MRI, 99 BRCA1 and 103 BRCA2 lesions in 187 women (mean age, 39...
August 10, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28792802/utility-of-bi-rads-assessment-category-4-subdivisions-for-screening-breast-mri
#20
Roberta M Strigel, Elizabeth S Burnside, Mai Elezaby, Amy M Fowler, Frederick Kelcz, Lonie R Salkowski, Wendy B DeMartini
OBJECTIVE: BI-RADS for mammography and ultrasound subdivides category 4 assessments by likelihood of malignancy into categories 4A (> 2% to ≤ 10%), 4B (> 10% to ≤ 50%), and 4C (> 50% to < 95%). Category 4 is not subdivided for breast MRI because of a paucity of data. The purpose of the present study is to determine the utility of categories 4A, 4B, and 4C for MRI by calculating their positive predictive values (PPVs) and comparing them with BI-RADS-specified rates of malignancy for mammography and ultrasound...
June 2017: AJR. American Journal of Roentgenology
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