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comorbidities in cerebral palsy

Osama Abas, Faten Abdelaziem, Ayman Kilany
BACKGROUND: Cerebral palsy is the most common cause of motor disability in children with a prevalence of 2-10/1,000 live births in the developing areas. AIM: The epidemiology, clinical picture, and associated comorbidities in CP have been extensively studied in high-resource countries, but in low-resource areas, including Africa, those studies are still lacking. METHODS: Cerebral palsy cases were prospectively recruited from every physiotherapy centre in Bani-Mazar city, Egypt, in a cross-sectional study from May 2015 to November 2015...
March 15, 2017: Open Access Macedonian Journal of Medical Sciences
Phylicia T Bediako, Rhonda BeLue, Marianne M Hillemeier
Immigrants in the U.S. often have comparatively favorable health outcomes despite relative socioeconomic disadvantage- a phenomenon termed the Immigrant Paradox. This study examined the relationship between family immigrant status and developmental problems among children born preterm. The 2011-2012 National Survey of Children's Health data collected through a telephone based survey based on parental report of prematurity and other comorbidities were analyzed using multivariate logistic regression analysis to examine seven developmental outcomes...
March 1, 2017: Journal of Immigrant and Minority Health
Brandon A Sherrod, Anastasia A Arynchyna, James M Johnston, Curtis J Rozzelle, Jeffrey P Blount, W Jerry Oakes, Brandon G Rocque
OBJECTIVE Surgical site infection (SSI) following CSF shunt operations has been well studied, yet risk factors for nonshunt pediatric neurosurgery are less well understood. The purpose of this study was to determine SSI rates and risk factors following nonshunt pediatric neurosurgery using a nationwide patient cohort and an institutional data set specifically for better understanding SSI. METHODS The authors reviewed the American College of Surgeons National Surgical Quality Improvement Program-Pediatric (ACS NSQIP-P) database for the years 2012-2014, including all neurosurgical procedures performed on pediatric patients except CSF shunts and hematoma evacuations...
April 2017: Journal of Neurosurgery. Pediatrics
Diego Cabral Lacerda, Kelli Nogueira Ferraz-Pereira, André Terácio, Bárbara Juacy Rodrigues Costa de Santana, Omar Guzman Quevedo, Raul Manhães-de-Castro, Ana Elisa Toscano
BACKGROUND: Children who suffer from cerebral palsy (CP) often present comorbidities in the form of orofacial dysfunctions. Studies in animals have contributed to elaborate potential therapies aimed at minimizing the chronic disability of the syndrome. OBJECTIVE: To systematically review the scientific literature regarding the possible effects that experimental models of CP can have on orofacial functions. METHODS: Two independent authors conducted a systematic review in the electronic databases Medline, Scopus, CINAHL, Web of Science and Lilacs, using Mesh and Decs terms in animal models...
February 4, 2017: Journal of Oral Rehabilitation
C Olivari-Philiponnet, F Roumenoff, M Schneider, C Chantran, M Picot, P Berlier, C Mottolese, J-C Bernard, C Vuillerot
Craniopharyngioma is a rare, benign central nervous system tumor, which may be a source of multiple complications, from endocrinology to vision, neurology and neurocognitive functions. This morbidity can lead to reduced participation in life activities, as described in the International Classification of Functioning, Disability, and Health. The primary objective of this study was to measure participation in life activities in a population of children and young adults affected by childhood craniopharyngioma, using the LIFE-H questionnaire (Assessment of Life Habits), validated as a social participation measurement tool in various pediatric disabilities...
December 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
Basil M Jan, Mohammed M Jan
Cerebral palsy (CP) is a common chronic motor disorder with associated cognitive, communicative, and seizure disorders. Children with CP have a higher risk of dental problems creating significant morbidity that can further affect their wellbeing and negatively impact their quality of life. Screening for dental disease should be part of the initial assessment of any child with CP. The objective of this article is to present an updated overview of dental health issues in children with CP and outline important preventative and practical strategies to the management of this common comorbidity...
October 2016: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
Andrew O Frank, Lorraine H De Souza
This article aims to describe the clinical features of electric powered indoor/outdoor wheelchair (EPIOC) users with cerebral palsy (CP) that are problematic to optimal prescription and to explore comorbidities, features of CP, and conditions secondary to disability impacting on equipment provision for children and adults. The method is a cross-sectional study of EPIOC users (n = 102) with a primary diagnosis of CP. This is a retrospective review of electronic and case note records of EPIOC recipients attending a specialist wheelchair service in 2007-2008...
October 7, 2016: Assistive Technology: the Official Journal of RESNA
Antonio Trabacca, Teresa Vespino, Antonella Di Liddo, Luigi Russo
Cerebral palsy (CP) is one of the most frequent causes of child disability in developed countries. Children with CP need lifelong assistance and care. The current prevalence of CP in industrialized countries ranges from 1.5 to 2.5 per 1,000 live births, with one new case every 500 live births. Children with CP have an almost normal life expectancy and mortality is very low. Despite the low mortality rate, 5%-10% of them die during childhood, especially when the severe motor disability is comorbid with epilepsy and severe intellectual disability...
2016: Journal of Multidisciplinary Healthcare
Clara D M van Karnebeek, Kristin Bowden, Elizabeth Berry-Kravis
BACKGROUND: Neurogenetic developmental conditions represent a heterogeneous group of rare inherited disorders with neurological manifestation during development. Treatments for these conditions have largely been supportive; however, a number of treatments are emerging which target the underlying physiology and offer great potential. Our aim was to present a state-of-the-art overview of the current and potential causal treatments available or under development for neurogenetic developmental conditions...
December 2016: Pediatric Neurology
Anju A Bendon, Khristine A George, Davandra Patel
INTRODUCTION: Neuromuscular scoliosis is a known risk factor for postoperative complications after corrective spine surgery. Few studies have looked at the preoperative factors affecting postoperative complications in children with cerebral palsy. AIM: The aim of this study was to examine the factors that might influence postoperative course in patients with cerebral palsy undergoing spine surgery for scoliosis. METHODS: Nineteen case notes of children with cerebral palsy who had spine surgery (2008-2014) were reviewed retrospectively...
October 2016: Paediatric Anaesthesia
Mette C Tollånes, Allen J Wilcox, Camilla Stoltenberg, Rolv T Lie, Dag Moster
OBJECTIVES: To explore the presence of shared underlying causes of cerebral palsy (CP) and other neurodevelopmental disorders, by examining risks of other disorders in siblings of children with CP. METHODS: We used Norwegian national registries to identify 1.4 million pairs of full siblings (singletons) and 28 000 sets of twins born from 1967 to 2006, identify stillbirths and neonatal deaths, and find individuals with CP, epilepsy, intellectual disability, autism spectrum disorders, attention-deficit/hyperactivity disorder, blindness, deafness, schizophrenia, and bipolar disorder...
August 2016: Pediatrics
Christopher Clark, Seckin O Ulualp
OBJECTIVES/HYPOTHESIS: Children with obstructive sleep apnea (OSA) may have multiple sites of upper airway obstruction (UAO). A wide variety of techniques has been used to evaluate UAO. Our aim was to compare findings of cine magnetic resonance imaging (MRI) and drug-induced sleep endoscopy (DISE) in identifying UAO sites in children with persistent OSA after adenotonsillectomy (AT). STUDY DESIGN: Retrospective chart review. MATERIAL AND METHODS: The medical records of children who underwent DISE and cine MRI were reviewed...
May 2017: Laryngoscope
Ahmet Selim Özkan, Mehmet Ali Erdoğan, Mukadder Şanlı, Osman Kaçmaz, Mahmut Durmuş, Cemil Çolak
OBJECTIVE: Most dental procedures can be performed with local anaesthesia, however noncompliant paediatric patients, patients with mental retardation or psychiatric disorders, severe anxiety, severe craniofacial anomalies and orofacial trauma may need general anaesthesia. In these patients accompanying central nervous system diseases and airway problems increase the risk of complications. Anaesthesia records of 467 cases of dental surgery performed under general anaesthesia between 2011-2014 is reported with information from the recent literature...
October 2015: Turkish Journal of Anaesthesiology and Reanimation
Melissa K Ainsworth, Anya S Evmenova, Michael Behrmann, Marci Jerome
For students who have severe and multiple disabilities including intellectual disability, complex communication needs, physical and/or sensory disabilities, and autism, there are many barriers to literacy acquisition. The purpose of this study was to teach letter-sound correspondence to small groups of students with significant intellectual disabilities and comorbid communication disorders using the ALL (Accessible Literacy Learning) curriculum. The eight participants in this study, who ranged in age from 11 to 16 years of age and had primary diagnoses of cerebral palsy, autism, Rett syndrome, Down syndrome, and intellectual disability, were placed into four groups for instruction in phonics...
September 2016: Research in Developmental Disabilities
Brandon A Sherrod, Dustin K Baker, Shawn R Gilbert
BACKGROUND: Perioperative bleeding requiring blood transfusion is a known complication of hip dysplasia (HD) surgery. Here we examine rates of, risk factors for, and postoperative complications associated with transfusion during HD surgery. METHODS: The National Surgical Quality Improvement Program (NSQIP) Pediatric database was queried for patients treated by an orthopaedist from 2012 to 2013. HD cases were categorized by Current Procedural Terminology codes into femoral osteotomies, acetabular osteotomies, combined femoral/acetabular osteotomies, and open reductions...
June 8, 2016: Journal of Pediatric Orthopedics
Agnes Elema, Trees A L Zalmstra, Anne M Boonstra, Unni G Narayanan, Heleen A Reinders-Messelink, Annette A J V D Putten
AIM: This was the first study to investigate the factors associated with health-related quality of life (HRQoL) in nonambulatory children with cerebral palsy (CP), based on a HRQoL measure specifically developed for this population. METHODS: The Dutch version of the Caregiver Priorities and Child Health Index of Life with Disabilities (CPCHILD-DV) was used to measure HRQoL. It was completed by 66 parents of 47 boys and 19 girls with nonambulatory CP aged between five and 18 years with gross motor function classification system (GMFCS) levels of IV and V...
September 2016: Acta Paediatrica
S Surender, Vykuntaraju K Gowda, K S Sanjay, G V Basavaraja, Naveen Benakappa, Asha Benakappa
INTRODUCTION: In children, health-related quality of life (HRQOL) includes parental impact and family functioning along with concepts of illness, functional status, mental health, and comfort. We are focusing on the impact of cerebral palsy (CP) on children's HRQOL and their families, and its relationship with gross motor dysfunction. SUBJECTS AND METHODS: CP children aged 3-10 years under regular neurology follow-up were enrolled. The HRQOL and motor severity were prospectively assessed using lifestyle assessment questionnaire-CP and gross motor function classification systems, respectively...
April 2016: Journal of Neurosciences in Rural Practice
David R Bearden, Baphaleng Monokwane, Esha Khurana, James Baier, Esther Baranov, Kate Westmoreland, Loeto Mazhani, Andrew P Steenhoff
BACKGROUND: Cerebral palsy is the most common cause of motor dysfunction in children worldwide and is often accompanied by multiple comorbidities. Although cerebral palsy has been studied extensively in high-resource settings, there are few published studies on cerebral palsy etiology, outcomes and comorbidities in low-resource settings. METHODS: Children with cerebral palsy were prospectively enrolled from inpatient and outpatient settings at a referral center in Gaborone, Botswana, in a cross-sectional study conducted from 2013 to 2014...
June 2016: Pediatric Neurology
John Garcia, Beverly Wical, William Wical, Leah Schaffer, Thomas Wical, Heather Wendorf, Samuel Roiko
AIM: To examine the risk of obstructive sleep apnea (OSA) in children with cerebral palsy (CP) and/or epilepsy. METHOD: This cross-sectional study employs the Pediatric Sleep Questionnaire (PSQ), the Gross Motor Function Classification System (GMFCS), and chart review to identify symptoms of OSA in children presenting to a multi-specialty pediatric healthcare institution. RESULTS: Two-hundred and fifteen patients were grouped into those with epilepsy (n=54), CP (n=18), both (n=55), and neither (comparison group, n=88)...
October 2016: Developmental Medicine and Child Neurology
Linda Zheng, Helen Hyun-Jin Do, Trent Sandercoe, Robyn V Jamieson, John R Grigg
BACKGROUND: To evaluate the aetiology of paediatric optic atrophy in an Australian population. DESIGN: Retrospective review of medical records was conducted at The Children's Hospital at Westmead, Sydney, Australia. PARTICIPANTS: Two hundred twenty-seven subjects <16 years who were diagnosed with optic atrophy on fundoscopic examination between 1979 and 2015 were included in the study. METHODS: Subjects were obtained from the hospital database, which codes diagnoses for all admissions, as well as the orthoptic department database, which codes diagnoses for ophthalmology department outpatients...
September 2016: Clinical & Experimental Ophthalmology
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