keyword
MENU ▼
Read by QxMD icon Read
search

Stewart

keyword
https://www.readbyqxmd.com/read/28549248/metastatic-chromophobe-renal-cell-carcinoma-treated-with-targeted-therapies-a-renal-cross-channel-group%C3%A2-study
#1
Emeline Colomba, Gwénaël Le Teuff, Tim Eisen, Grant D Stewart, Kate Fife, James Larkin, Andrea Biondo, Lisa Pickering, Anandagopal Srinivasan, Helen Boyle, Lisa Derosa, Cora N Sternberg, Federica Recine, Christy Ralph, Carolina Saldana, Philippe Barthélémy, Jean Christophe Bernhard, Howard Gurney, Gregory Verhoest, Elodie Vauleon, Pierre Bigot, Julien Berger, Christian Pfister, Gwenaelle Gravis, Jean-Michel Rodier, Stéphane Culine, Armelle Caty, Frederic Rolland, Franck Priou, Bernard Escudier, Laurence Albiges
BACKGROUND: Treatment of non-clear cell renal cell carcinoma (RCC) remains controversial despite several recent prospective studies of targeted therapies (TT). Often Vascular Endothelial growth Factor (VEGF) and Mammalian Target of Rapamycin (mTOR) inhibitors are used, extrapolating the data from use of these agents in clear cell RCC. METHODS: We performed a retrospective data analysis within the Renal Cross Channel Group to determine metastatic chromophobe RCC (mChRCC) outcomes in the TT era...
May 23, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28549195/the-british-society-for-rheumatology-guideline-for-the-management-of-gout
#2
Michelle Hui, Alison Carr, Stewart Cameron, Graham Davenport, Michael Doherty, Harry Forrester, Wendy Jenkins, Kelsey M Jordan, Christian D Mallen, Thomas M McDonald, George Nuki, Anthony Pywell, Weiya Zhang, Edward Roddy
No abstract text is available yet for this article.
May 26, 2017: Rheumatology
https://www.readbyqxmd.com/read/28549177/the-british-society-for-rheumatology-guideline-for-the-management-of-gout
#3
Michelle Hui, Alison Carr, Stewart Cameron, Graham Davenport, Michael Doherty, Harry Forrester, Wendy Jenkins, Kelsey M Jordan, Christian D Mallen, Thomas M McDonald, George Nuki, Anthony Pywell, Weiya Zhang, Edward Roddy
No abstract text is available yet for this article.
May 26, 2017: Rheumatology
https://www.readbyqxmd.com/read/28549089/development-of-a-sustained-release-voriconazole-containing-thermogel-for-subconjunctival-injection-in-horses
#4
Rosemary S Cuming, Eva M Abarca, Sue Duran, Anne A Wooldridge, Allison J Stewart, William Ravis, R Jayachandra Babu, Yuh-Jing Lin, Terri Hathcock
Purpose: To determine in vitro release profiles, transcorneal permeation, and ocular injection characteristics of a voriconazole-containing thermogel suitable for injection into the subconjunctival space (SCS). Methods: In vitro release rate of voriconazole (0.3% and 1.5%) from poly (DL-lactide-co-glycolide-b-ethylene glycol-b-DL-lactide-co-glycolide) (PLGA-PEG-PLGA) thermogel was determined for 28 days. A Franz cell diffusion chamber was used to evaluate equine transcorneal and transscleral permeation of voriconazole (1...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28547673/valvular-heart-disease-in-cancer-patients-etiology-diagnosis-and-management
#5
REVIEW
Merrill H Stewart, Eiman Jahangir, Nichole M Polin
Cardiac valvular disease as consequence of radiation and chemotherapy during treatment for malignancy is growing in its awareness. While the overwhelming emphasis in this population has been on the monitoring and preservation of left ventricular systolic function, we are now developing a greater appreciation for the plethora of cardiac sequelae beyond this basic model. To this end many institutions across the country have developed cardio-oncology programs, which are collaborative practices between oncologists and cardiologists in order to minimize a patient's cardiovascular risk while allowing them to receive the necessary treatment for their cancer...
July 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28546772/the-impact-of-socioeconomic-status-and-multimorbidity-on-mortality-a-population-based-cohort-study
#6
Nikoline Lund Jensen, Henrik Søndergaard Pedersen, Mogens Vestergaard, Stewart W Mercer, Charlotte Glümer, Anders Prior
OBJECTIVE: Multimorbidity (MM) is more prevalent among people of lower socioeconomic status (SES), and both MM and SES are associated with higher mortality rates. However, little is known about the relationship between SES, MM, and mortality. This study investigates the association between educational level and mortality, and to what extent MM modifies this association. METHODS: We followed 239,547 individuals invited to participate in the Danish National Health Survey 2010 (mean follow-up time: 3...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/28546514/the-nuclear-matrix-protein-ciz1-facilitates-localization-of-xist-rna-to-the-inactive-x-chromosome-territory
#7
Rebeca Ridings-Figueroa, Emma R Stewart, Tatyana B Nesterova, Heather Coker, Greta Pintacuda, Jonathan Godwin, Rose Wilson, Aidan Haslam, Fred Lilley, Renate Ruigrok, Sumia A Bageghni, Ghadeer Albadrani, William Mansfield, Jo-An Roulson, Neil Brockdorff, Justin F X Ainscough, Dawn Coverley
The nuclear matrix protein Cip1-interacting zinc finger protein 1 (CIZ1) promotes DNA replication in association with cyclins and has been linked to adult and pediatric cancers. Here we show that CIZ1 is highly enriched on the inactive X chromosome (Xi) in mouse and human female cells and is retained by interaction with the RNA-dependent nuclear matrix. CIZ1 is recruited to Xi in response to expression of X inactive-specific transcript (Xist) RNA during the earliest stages of X inactivation in embryonic stem cells and is dependent on the C-terminal nuclear matrix anchor domain of CIZ1 and the E repeats of Xist CIZ1-null mice, although viable, display fully penetrant female-specific lymphoproliferative disorder...
May 25, 2017: Genes & Development
https://www.readbyqxmd.com/read/28546511/the-nanci-nkx2-1-gene-duplex-buffers-nkx2-1-expression-to-maintain-lung-development-and-homeostasis
#8
Michael J Herriges, David J Tischfield, Zheng Cui, Michael P Morley, Yumiao Han, Apoorva Babu, Su Li, MinMin Lu, Isis Cendan, Benjamin A Garcia, Stewart A Anderson, Edward E Morrisey
A subset of long noncoding RNAs (lncRNAs) is spatially correlated with transcription factors (TFs) across the genome, but how these lncRNA-TF gene duplexes regulate tissue development and homeostasis is unclear. We identified a feedback loop within the NANCI (Nkx2.1-associated noncoding intergenic RNA)-Nkx2.1 gene duplex that is essential for buffering Nkx2.1 expression, lung epithelial cell identity, and tissue homeostasis. Within this locus, Nkx2.1 directly inhibits NANCI, while NANCI acts in cis to promote Nkx2...
May 25, 2017: Genes & Development
https://www.readbyqxmd.com/read/28545632/a-cautionary-tale-of-2-leaflets-tavr-in-bicuspid-aortic-valve-stenosis
#9
EDITORIAL
Itsik Ben-Dor, Allan Stewart
No abstract text is available yet for this article.
May 30, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28545492/non-participants-in-policy-efforts-to-promote-evidence-based-practices-in-a-large-behavioral-health-system
#10
Rebecca E Stewart, Danielle R Adams, David S Mandell, Gayatri Nangia, Lauren Shaffer, Arthur C Evans, Ronnie Rubin, Shawna Weaver, Trevor R Hadley, Rinad S Beidas
BACKGROUND: System-wide training initiatives to support and implement evidence-based practices (EBPs) in behavioral health systems have become increasingly widespread. Understanding more about organizations who do not participate in EBP training initiatives is a critical piece of the dissemination and implementation puzzle if we endeavor to increase access in community settings. METHODS: We conducted 30 1-h semi-structured interviews with leaders in non-participating agencies who did not formally participate in system-wide training initiatives to implement EBPs in the City of Philadelphia, with the goal to understand why they did not participate...
May 25, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28544009/a-cluster-randomised-controlled-trial-evaluating-the-effects-of-delaying-onset-of-adolescent-substance-abuse-on-cognitive-development-and-addiction-following-a-selective-personality-targeted-intervention-program-the-co-venture-trial
#11
Maeve O'Leary-Barrett, Benoit Mâsse, Robert Pihl, Sherry Stewart, Jean R Séguin, Patricia Conrod
AIMS: Substance use and binge drinking during early adolescence are associated with neurocognitive abnormalities, mental health problems and an increased risk for future addiction. The trial aims to evaluate the protective effects of an evidence-based substance use prevention program on the onset of alcohol and drug use in adolescence, as well as on cognitive, mental health and addiction outcomes over 5 years. DESIGN: Thirty-eight high schools will be recruited, with a final sample of 31 schools assigned to intervention or control conditions (approximately 3800 youth)...
May 21, 2017: Addiction
https://www.readbyqxmd.com/read/28543939/symptom-appraisal-help-seeking-and-lay-consultancy-for-symptoms-of-head-and-neck-cancer
#12
J A Queenan, Benjamin Gottlieb, Deb Feldman-Stewart, Stephen Hall, Jonathan Irish, Patti Groome
BACKGROUND: Early diagnosis is important in head and neck cancer (HNC) patients in order to maximize the effectiveness of the treatments and minimize the debilitation associated with both the cancer and the invasive treatments of advanced disease. Many patients present with advanced disease, and there is little understanding as to why. This study investigated patients' symptom appraisal, help-seeking and lay-consultancy up to the time they first went to see a health care professional (HCP)...
May 23, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28543426/predictors-and-pathways-of-language-and-motor-development-in-four-prospective-cohorts-of-young-children-in-ghana-malawi-and-burkina-faso
#13
Elizabeth L Prado, Souheila Abbeddou, Seth Adu-Afarwuah, Mary Arimond, Per Ashorn, Ulla Ashorn, Jaden Bendabenda, Kenneth H Brown, Sonja Y Hess, Emma Kortekangas, Anna Lartey, Kenneth Maleta, Brietta M Oaks, Eugenia Ocansey, Harriet Okronipa, Jean Bosco Ouédraogo, Anna Pulakka, Jérôme W Somé, Christine P Stewart, Robert C Stewart, Stephen A Vosti, Elizabeth Yakes Jimenez, Kathryn G Dewey
BACKGROUND: Previous reviews have identified 44 risk factors for poor early child development (ECD) in low- and middle-income countries. Further understanding of their relative influence and pathways is needed to inform the design of interventions targeting ECD. METHODS: We conducted path analyses of factors associated with 18-month language and motor development in four prospective cohorts of children who participated in trials conducted as part of the International Lipid-Based Nutrient Supplements (iLiNS) Project in Ghana (n = 1,023), Malawi (n = 675 and 1,385), and Burkina Faso (n = 1,122)...
May 23, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28543391/medication-discrepancies-in-the-dental-record-and-impact-of-pharmacist-led-intervention
#14
Hailey J Choi, Autumn L Stewart, Chunhao Tu
BACKGROUND: Patients frequently use medications with potential implications for oral health and dental procedures, yet little is known about the accuracy of medication lists available to dentists. The aims of this study were to describe the frequency and clinical implications of medication discrepancies in the dental record (phase 1) and to evaluate the impact of pharmacist intervention on medication reconciliation processes in dental practice (phase 2). METHODS: A prospective, single-centre study evaluating adults receiving dental care was conducted...
May 20, 2017: International Dental Journal
https://www.readbyqxmd.com/read/28543184/a-systematic-review-of-patient-reported-measures-associated-with-vestibular-dysfunction
#15
REVIEW
Vicky M Stewart, M Dilani Mendis, Nancy Low Choy
OBJECTIVES/HYPOTHESIS: Use of clinical questionnaires to assist in the screening of vestibular disorders in the acute hospital setting is needed. The objective is to detail the clinimetric properties and clinical utility of patient-reported questionnaires for quantifying dizziness/vertigo symptoms associated with vestibular dysfunction, and to determine validity and utility for screening dizziness/vertigo in the emergency department. DATA SOURCES: We performed a systematic review of PubMed, CINAHL, Embase, and Web of Science in May 2015...
May 23, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28542981/dental-providers-and-pharmacists-a-call-for-enhanced-interprofessional-collaboration
#16
Henning Lygre, Reidun Lisbet Skeide Kjome, Hailey Choi, Autumn L Stewart
Reports concerning medication discrepancies in dental records indicate that the concept of interprofessional collaboration between the dental team and pharmacists should be considered at all educational levels in dentistry and pharmacy. Inclusion of oral health as a therapeutic area in didactic pharmacy curricula is needed. Early exposure of dental students and student pharmacists to collaborative practices through interprofessional educational experiences may create a higher degree of awareness of the role of each profession and the potential to improve patient outcomes...
May 21, 2017: International Dental Journal
https://www.readbyqxmd.com/read/28542926/effect-of-spironolactone-on-exercise-tolerance-and-arterial-function-in-older-adults-with-heart-failure-with-preserved-ejection-fraction
#17
Bharathi Upadhya, William G Hundley, Peter H Brubaker, Timothy M Morgan, Kathryn P Stewart, Dalane W Kitzman
OBJECTIVES: To evaluate the effects of an aldosterone antagonist on exercise intolerance in older adults with heart failure and preserved ejection fraction (HFpEF). DESIGN: Randomized, placebo-controlled, double-blind trial. SETTING: Academic medical center, Winston-Salem, North Carolina. PARTICIPANTS: Older adults (N = 80, aged 71 ± 1; 80% female) with stable compensated HFpEF and controlled blood pressure (BP)...
May 19, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28542925/a-new-insight-into-the-ability-to-resist-ischemic-brain-injury-does-hibernation-matter-an-editorial-comment-for-arctic-ground-squirrel-hippocampus-tolerates-oxygen-glucose-deprivation-independent-of-hibernation-season-even-when-not-hibernating-and-after-atp
#18
EDITORIAL
Thomas I Nathaniel, Bianca Stewart, Jessica Williams, Michael Hood, Adebobola Imeh-Nathaniel
Read the commented article 'Arctic ground squirrel hippocampus tolerates oxygen glucose deprivation independent of hibernation season even when not hibernating and after ATP depletion, acidosis and glutamate efflux' on doi: 10.1111/jnc.13996.
May 24, 2017: Journal of Neurochemistry
https://www.readbyqxmd.com/read/28542797/application-of-geographic-information-systems-to-investigating-associations-between-social-status-and-burial-location-in-medieval-trino-vercellese-piedmont-italy
#19
Marissa C Stewart, Giuseppe Vercellotti
OBJECTIVES: Socioeconomic status differences in skeletal populations are often inferred from skeletal indicators of stress and burial location. However, to date, the association between osteometric parameters and spatial location in relation to socioeconomic status in medieval Italy has not been explicitly tested. MATERIALS AND METHODS: This study examined the spatial distribution of osteometric data in the medieval (8th-13th c.) cemetery of San Michele di Trino (Trino Vercellese, VC, Italy) to determine whether skeletal correlates of socioeconomic status correspond with privileged burial locations...
May 24, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28542585/highly-efficient-maternal-fetal-zika-virus-transmission-in-pregnant-rhesus-macaques
#20
Sydney M Nguyen, Kathleen M Antony, Dawn M Dudley, Sarah Kohn, Heather A Simmons, Bryce Wolfe, M Shahriar Salamat, Leandro B C Teixeira, Gregory J Wiepz, Troy H Thoong, Matthew T Aliota, Andrea M Weiler, Gabrielle L Barry, Kim L Weisgrau, Logan J Vosler, Mariel S Mohns, Meghan E Breitbach, Laurel M Stewart, Mustafa N Rasheed, Christina M Newman, Michael E Graham, Oliver E Wieben, Patrick A Turski, Kevin M Johnson, Jennifer Post, Jennifer M Hayes, Nancy Schultz-Darken, Michele L Schotzko, Josh A Eudailey, Sallie R Permar, Eva G Rakasz, Emma L Mohr, Saverio Capuano, Alice F Tarantal, Jorge E Osorio, Shelby L O'Connor, Thomas C Friedrich, David H O'Connor, Thaddeus G Golos
Infection with Zika virus (ZIKV) is associated with human congenital fetal anomalies. To model fetal outcomes in nonhuman primates, we administered Asian-lineage ZIKV subcutaneously to four pregnant rhesus macaques. While non-pregnant animals in a previous study contemporary with the current report clear viremia within 10-12 days, maternal viremia was prolonged in 3 of 4 pregnancies. Fetal head growth velocity in the last month of gestation determined by ultrasound assessment of head circumference was decreased in comparison with biparietal diameter and femur length within each fetus, both within normal range...
May 2017: PLoS Pathogens
keyword
keyword
75070
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"