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https://www.readbyqxmd.com/read/28615544/evidence-of-associations-between-brain-derived-neurotrophic-factor-bdnf-serum-levels-and-gene-polymorphisms-with-tinnitus
#1
Aysun Coskunoglu, Seda Orenay-Boyacioglu, Artuner Deveci, Mustafa Bayam, Ece Onur, Arzu Onan, Fethi S Cam
BACKGROUND: Brain-derived neurotrophic factor (BDNF) gene polymorphisms are associated with abnormalities in regulation of BDNF secretion. Studies also linked BDNF polymorphisms with changes in brainstem auditory-evoked response test results. Furthermore, BDNF levels are reduced in tinnitus, psychiatric disorders, depression, dysthymic disorder that may be associated with stress, conversion disorder, and suicide attempts due to crises of life. For this purpose, we investigated whether there is any role of BDNF changes in the pathophysiology of tinnitus...
May 2017: Noise & Health
https://www.readbyqxmd.com/read/28606495/personality-traits-in-psychogenic-nonepileptic-seizures-pnes-and-psychogenic-movement-disorder-pmd-neuroticism-and-perfectionism
#2
Vindhya Ekanayake, Sarah Kranick, Kathrin LaFaver, Arshi Naz, Anne Frank Webb, W Curt LaFrance, Mark Hallett, Valerie Voon
OBJECTIVE: Psychogenic movement disorder (PMD) and psychogenic nonepileptic seizures (PNES) are two subtypes of conversion disorder (CD). In this case-control study, we asked whether these subtypes varied as a function of personality and history of childhood abuse. METHODS: Fifty-nine patients with PMD from the Human Motor Control Section Clinic at the National Institutes of Health, 43 patients with PNES from the Rhode Island Hospital Neuropsychiatry and Behavioral Neurology Division, and 26 healthy volunteers (HC) received a battery of neurological, psychiatric and psychological assessments, including the NEO Personality Inventory Revised (NEO PI-R), the Childhood Trauma Questionnaire (CTQ), and the Traumatic Life Events Questionnaire (TLEQ)...
June 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28582839/beneficial-effect-of-faradic-stimulation-treatment-on-the-rehabilitation-of-hysterical-paraplegia
#3
Ozgur Zeliha Karaahmet, Eda Gurcay, Hande Sancioglu, Ece Unlu, Aytul Cakci
Hysterical paralysis, a type of conversion disorder, presents with the loss of motor or sensory function. Although this disorder is nonorganic, it resembles the symptoms of a structural disease of the nervous system. It is generally associated with a traumatic or social event. The patients often require excessive testing and comprehensive assessment in exposing this psychogenic ailment. We reported the most dramatic type of conversion disorder, hysterical paralysis, in which full recovery was obtained with early recognition and rehabilitation approach including faradic stimulation...
May 12, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28571244/psychogenic-belching-a-case-report
#4
Vivekkumar Ashok Nagarale, Suyog Vijay Jaiswal, Vishal Ashok Sawant, Vihang N Vahia
Conversion symptoms usually appear with emotional conflicts of the patient. Belching's psychogenic aetiology is not unheard of and can be a manifestation of conversion disorder though rare. Current case is of a middle aged woman presenting with belching unresponsive to medical management. The patient improved after supportive psychotherapy sessions and placebo medication.
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28566953/conversion-disorder-comorbidity-and-childhood-trauma
#5
Fatma Akyüz, Peykan G Gökalp, Sezgin Erdiman, Serap Oflaz, Çağatay Karşidağ
INTRODUCTION: The aim of this study is to examine the socio-demographic and clinical characteristics, the presence of comorbidity, and the link with childhood traumatic experiences in patients with conversion disorder (CD) in a psychiatric outpatient clinic. METHODS: A total of 60 literate, female patients between 18 and 65 years of age who were referred to the general psychiatry outpatient clinic and who were diagnosed with conversion disorder according to the DSM-IV diagnostic criteria were included in the study...
March 2017: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/28553554/a-case-of-sporadic-creutzfeldt-jakob-disease-presenting-as-conversion-disorder
#6
Nikhil Yegya-Raman, Rehan Aziz, Daniel Schneider, Anthony Tobia, Megan Leitch, Onyi Nwobi
Background. Creutzfeldt-Jakob disease is a rare disorder of the central nervous system. Its initial diagnosis may be obscured by its variable presentation. This case report illustrates the complexity of diagnosing this disease early in the clinical course, especially when the initial symptoms may be psychiatric. It offers a brief review of the literature and reinforces a role for consultation psychiatry services. Methods. PUBMED/MEDLINE was searched using the terms "Creutzfeldt-Jakob disease", "psychiatric symptoms", "conversion disorder", "somatic symptom disorder", "functional movement disorder", and "functional neurologic disorder"...
2017: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/28529870/symptom-specific-amygdala-hyperactivity-modulates-motor-control-network-in-conversion-disorder
#7
Thomas Hassa, Alexandra Sebastian, Joachim Liepert, Cornelius Weiller, Roger Schmidt, Oliver Tüscher
Initial historical accounts as well as recent data suggest that emotion processing is dysfunctional in conversion disorder patients and that this alteration may be the pathomechanistic neurocognitive basis for symptoms in conversion disorder. However, to date evidence of direct interaction of altered negative emotion processing with motor control networks in conversion disorder is still lacking. To specifically study the neural correlates of emotion processing interacting with motor networks we used a task combining emotional and sensorimotor stimuli both separately as well as simultaneously during functional magnetic resonance imaging in a well characterized group of 13 conversion disorder patients with functional hemiparesis and 19 demographically matched healthy controls...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28507360/psychometric-properties-of-conversion-disorder-scale-revised-cds-for-children
#8
Tazvin Ijaz, Attikah Nasir, Naema Sarfraz, Shirmeen Ijaz
OBJECTIVE: To revise conversion disorder scale and to establish the psychometric properties of the revised scale. METHODS: This case-control study was conducted from February to June, 2014, at the Government College University, Lahore, Pakistan, and comprised schoolchildren and children with conversion disorder. In order to generate items for revised version of conversion disorder scale, seven practising mental health professionals were consulted. A list of 42 items was finalised for expert ratings...
May 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28471555/-conversion-disorder-functional-neuroimaging-and-neurobiological-mechanisms
#9
J Lejeune, C Piette, E Salmon, G Scantamburlo
Conversion disorder is a psychiatric disorder often encountered in neurology services. This condition without organic lesions was and still is sometimes referred as an imaginary illness or feigning. However, the absence of organic lesions does not exclude the possibility of cerebral dysfunction. The etiologic mechanisms underlying this disorder remain uncertain even today.The advent of cognitive and functional imaging opens up a field of exploration for psychiatry in understanding the neurobiological mechanisms underlying mental disorders and especially the conversion disorder...
April 2017: Revue Médicale de Liège
https://www.readbyqxmd.com/read/28438254/validity-and-reliability-of-the-spanish-version-of-the-somatoform-dissociation-questionnaire-sdq-20
#10
Ana I González-Vázquez, Lucía Del Río-Casanova, Natalia Seijo-Ameneiros, Paloma Cabaleiro-Fernández, Teresa Seoane-Pillado, Ania Justo-Alonso, Miguel A Santed-Germán
BACKGROUND: The Somatoform Dissociation Questionnaire (SDQ-20) is a self-reported questionnaire measuring somatoform dissociation. The aim of this study is to analyze the psychometric properties of the Spanish version of the SDQ-20 and its short version (SDQ-5). METHODS: Validity and reliability were examined in a sample of 360 psychiatric outpatients: 38 dissociative (conversion) disorders, 30 dissociative (psychoform) disorders, and 292 patients suffering from other disorders...
May 2017: Psicothema
https://www.readbyqxmd.com/read/28434123/conversion-disorder-functional-neurological-symptom-disorder-and-chronic-pain-comorbidity-assessment-and-treatment
#11
REVIEW
Patricia Tsui, Andrew Deptula, Derek Y Yuan
PURPOSE OF REVIEW: This paper examines the overlap of conversion disorder with chronic pain conditions, describes ways to assess for conversion disorder, and provides an overview of evidence-based treatments for conversion disorder and chronic pain, with a focus on conversion symptoms. RECENT FINDINGS: Conversion disorder is a significant problem that warrants further study, given that there are not many well-established guidelines. Accurate and timely assessment should help move treatment in a more fruitful direction and avoid unnecessary medical interventions...
June 2017: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/28424653/disentangling-stigma-from-functional-neurological-disorders-conference-report-and-roadmap-for-the-future
#12
Karen S Rommelfanger, Stewart A Factor, Suzette LaRoche, Phyllis Rosen, Raymond Young, Mark H Rapaport
A multidisciplinary expert review of key issues and future directions from the conference "Controversial labels and clinical uncertainties: psychogenic disorders, conversion disorder, and functional symptoms." On October 9 and 10, 2015, a conference entitled "Controversial labels and clinical uncertainties: psychogenic disorders, conversion disorder, and functional symptoms" was held at the Center for Ethics, Emory University, Atlanta, GA, USA. This conference brought together a select group of 30 distinguished thought leaders and practitioners, including ethicists, researchers, clinicians, humanities scholars, and advocates to discuss the unique challenges and controversies related to the diagnosis, treatment, and stigma for patients with what is currently recognized as functional ("psychogenic") neurological disorders...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28416565/cingulo-insular-structural-alterations-associated-with-psychogenic-symptoms-childhood-abuse-and-ptsd-in-functional-neurological-disorders
#13
David L Perez, Nassim Matin, Arthur Barsky, Victor Costumero-Ramos, Sara J Makaretz, Sigrid S Young, Jorge Sepulcre, W Curt LaFrance, Matcheri S Keshavan, Bradford C Dickerson
OBJECTIVE: Adverse early-life events are predisposing factors for functional neurological disorder (FND) and post-traumatic stress disorder (PTSD). Cingulo-insular regions are implicated in the biology of both conditions and are sites of stress-mediated neuroplasticity. We hypothesised that functional neurological symptoms and the magnitude of childhood abuse would be associated with overlapping anterior cingulate cortex (ACC) and insular volumetric reductions, and that FND and PTSD symptoms would map onto distinct cingulo-insular areas...
June 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28336681/accuracy-and-reliability-of-stroke-diagnosis-in-the-pediatric-emergency-department
#14
Mark T Mackay, Adriana Yock-Corrales, Leonid Churilov, Paul Monagle, Geoffrey A Donnan, Franz E Babl
BACKGROUND AND PURPOSE: Access to acute stroke interventions in the emergency department (ED) relies on correct clinical diagnosis. Our aims were to determine the accuracy and reliability of pediatric ED physician diagnosis of childhood stroke and other conditions presenting with brain attack symptoms. METHODS: Prospective study of consecutive children aged 1 month to 18 years presenting to the ED from June 2009 to December 2010 with focal neurological deficits...
March 23, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28314521/orienting-reaction-may-help-recognition-of-patients-with-psychogenic-nonepileptic-seizures
#15
Murat Yalçın, Evrim Tellioğlu, Ayşegül Gündüz, Mine Özmen, Naz Yeni, Çiğdem Özkara, Meral E Kiziltan
OBJECTIVE: Psychogenic nonepileptic seizures (PNES) are abrupt, paroxysmal changes in behavior or consciousness that may phenomenologically resemble epileptic seizures. Given the known association between anxiety and PNES, we hypothesized that in these subjects there may be evidence that the nervous system is hypersensitive to external stimuli. We aimed to test our hypothesis by means of the auditory startle reaction (ASR). By investigating ASR, we also had the opportunity to test presence of orienting reaction, which is generally defined as the second phase of response after the auditory stimulus, with longer latency...
March 14, 2017: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/28276597/an-international-perspective-on-feigned-mental-disabilities-conceptual-issues-and-continuing-controversies
#16
Thomas Merten, Richard Rogers
In forensic contexts, an increased prevalence of feigned symptom presentations should be expected, although it will probably vary by the context and specific forensic issue. Forensic experts should examine this possibility proactively while maintaining a balanced perspective that actively considers clinical data for both feigning and genuine responding. Psychological measures and standardized methods developed for feigning and other response styles can facilitate these often complex determinations. The current article provides an international perspective on the issue of feigned mental disabilities...
March 2017: Behavioral Sciences & the Law
https://www.readbyqxmd.com/read/28274339/conversion-disorder-a-systematic-review-of-current-terminology
#17
Juen Mei Ding, Richard Antony Alexander Kanaan
OBJECTIVE: It has been argued that the label given to unexplained neurological symptoms is an important contributor to their often poor acceptance, and there has been recent debate on proposals to change the name from conversion disorder. There have been multiple studies of layperson and clinician preference and this article aimed to review these. DESIGN: Multiple databases were searched using terms including "conversion disorder" and "terminology", and relative preferences for the terms extracted...
March 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/28250569/dissociative-motor-disorder
#18
Arya Jith, Dinesh Narayanan
Conversion disorders are more prevalent in childhood and adolescence, especially in females. They are usually associated with stressors and symptoms usually reflect a means to avoid the stressor, or also with a primary and secondary gain. This case report involves a similar situation where a young girl was treated successfully with diazepam, therapeutic nerve conduction study, and behavioral psychotherapy.
January 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28235779/are-psychogenic-non-epileptic-seizures-just-another-symptom-of-conversion-disorder
#19
Richard A A Kanaan, Roderick Duncan, Laura H Goldstein, Joseph Jankovic, Andrea E Cavanna
BACKGROUND: Psychogenic non-epileptic seizures (PNES) are classified with other functional neurological symptoms as 'Conversion Disorder', but there are reasons to wonder whether this symptomatology constitutes a distinct entity. METHODS: We reviewed the literature comparing PNES with other functional neurological symptoms. RESULTS: We find eight studies that directly examined this question. Though all but one found significant differences-notably in presenting age, trauma history, and dissociation-they were divided on whether these differences represented an important distinction...
May 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28231395/functional-connectivity-in-amygdalar-sensory-pre-motor-networks-at-rest-new-evidence-from-the-human-connectome-project
#20
Nicola Toschi, Andrea Duggento, Luca Passamonti
The word 'e-motion' derives from the Latin word 'ex-moveo' which literally means 'moving away from something/somebody'. Emotions are thus fundamental to prime action and goal-directed behavior with obvious implications for individual's survival. However, the brain mechanisms underlying the interactions between emotional and motor cortical systems remain poorly understood. A recent diffusion tensor imaging study in humans has reported the existence of direct anatomical connections between the amygdala and sensory/(pre)motor cortices, corroborating an initial observation in animal research...
February 23, 2017: European Journal of Neuroscience
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