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pulmonary nodule diagnosis

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https://www.readbyqxmd.com/read/28932568/needle-based-confocal-laser-endomicroscopy-in-the-diagnosis-of-peripheral-pulmonary-nodule-a-preliminary-report
#1
Zhuquan Su, Changhao Zhong, Shiyue Li, Xiaobo Chen, Yu Chen, Chunli Tang
Lung cancer is one of the most fatal cancers in the world. To early distinguish benign and malignant pulmonary nodule is critical for disease prognosis. Confocal laser endomicroscopy (CLE) can be used to explore bronchus mucous membrane, alveolar elastic fiber structures and microvessels, and could be helpful for the diagnostic imaging and for the localization guidance. In this report, we presented two cases of peripheral pulmonary nodule. Under the guidance of X-ray and endobronchial ultrasound, needle-based confocal laser endomicroscopy (nCLE) could directly approach the peripheral pulmonary nodule via an exploratory puncture needle...
August 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28927977/the-role-of-pulmonary-metastasectomy-for-hepatoblastoma-in-children-with-metastasis-at-diagnosis-results-from-the-jplt-2-study
#2
Tomoro Hishiki, Kenichiro Watanabe, Kohmei Ida, Ken Hoshino, Tomoko Iehara, Yuki Aoki, Takuro Kazama, Kentaro Kihira, Yuichi Takama, Tomoaki Taguchi, Junya Fujimura, Shohei Honda, Kimikazu Matsumoto, Makiko Mori, Michihiro Yano, Akiko Yokoi, Yukichi Tanaka, Hiroshi Fuji, Osamu Miyazaki, Kenichi Yoshimura, Tetsuya Takimoto, Eiso Hiyama
BACKGROUND/PURPOSE: The purpose of this study was to clarify the role of pulmonary metastasectomy in hepatoblastomas with lung metastasis at diagnosis. We reviewed cases enrolled in the JPLT-2 study. METHODS: A total of 360 cases with hepatoblastoma were enrolled. The clinical courses and outcome of 60 cases with pulmonary metastasis at diagnosis were reviewed, focusing on metastasectomy. RESULTS: Induction chemotherapy resulted in eradication of nodules in 26, residual nodules in 33, and early treatment-related death in one...
September 4, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28923146/cannon-ball-diagnosis-and-management-in-a-flight-attendant-candidate
#3
Meryem Zerrik, Houda Echchachoui, Zakaria Iloughmane, Choukri El'mhadi, Salaheddine Elkhader, Laila Benaissa, Mohamed Chemsi
BACKGROUND: ''Cannon ball'' opacities on chest X-rays are a common manifestation of hematogenous dissemination of a malignant tumor in the lungs. They indicate an advanced stage of disease with a very grim prognosis in terms of cure and survival. In aerospace medicine, this aspect means the patient is unfit for flight duties. Nonmetastatic etiologies of pulmonary nodules are rare. We report a case of cannon ball opacities discovered fortuitously during an admission visit. CASE REPORT: A 23-yr-old flight attendant candidate came to the Aeromedical Expertise Center of the Military Hospital in Rabat for medical evaluation...
October 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28915902/development-and-clinical-application-of-radiomics-in-lung-cancer
#4
REVIEW
Bojiang Chen, Rui Zhang, Yuncui Gan, Lan Yang, Weimin Li
Since the discovery of X-rays at the end of the 19(th) century, medical imageology has progressed for 100 years, and medical imaging has become an important auxiliary tool for clinical diagnosis. With the launch of the human genome project (HGP) and the development of various high-throughput detection techniques, disease exploration in the post-genome era has extended beyond investigations of structural changes to in-depth analyses of molecular abnormalities in tissues, organs and cells, on the basis of gene expression and epigenetics...
September 15, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28910817/the-lung-in-dysregulated-states-of-humoral-immunity
#5
Yurdagül Uzunhan, Florence Jeny, Marianne Kambouchner, Morgane Didier, Diane Bouvry, Hilario Nunes, Jean-François Bernaudin, Dominique Valeyre
In common variable immunodeficiency, lung manifestations are related to different mechanisms: recurrent pneumonias due to encapsulated bacteria responsible for diffuse bronchiectasis, diffuse infiltrative pneumonia with various patterns, and lymphomas, mostly B cell extranodal non-Hodgkin type. The diagnosis relies on significant serum Ig deficiency and the exclusion of any primary or secondary cause. Histopathology may be needed. Immunoglobulin (IgG) replacement is crucial to prevent infections and bronchiectasis...
September 15, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28900554/primary-epithelioid-angiosarcoma-of-lung-radiologic-and-clinicopathologic-correlation
#6
Fung Him Ng, San Ming Yu, Ophelia Ka Heng Wai, James Chi Sang Chan
Primary pulmonary angiosarcoma is extremely rare. It is often characterized by a clinically indolent course and delayed diagnosis. To date, there have been <20 cases reported. By far, little article correlates the clinical presentation, the imaging findings with the pathology. The authors present a case of middle-aged gentleman with primary pulmonary epithelioid angiosacroma which we initially thought as tuberculosis (TB) infection. A 60-year-old gentleman, with a history of 6 months on and off blood stained sputum, was admitted for an episode of massive hemoptysis...
2017: Journal of Clinical Imaging Science
https://www.readbyqxmd.com/read/28899426/benign-metastasizing-leiomyoma-presenting-as-multiple-cystic-pulmonary-nodules-a-case-report
#7
Yeong Hun Choe, So Yeon Jeon, Yoon Chae Lee, Myung Ja Chung, Seung Yong Park, Yong Chul Lee, So Ri Kim
BACKGROUND: Benign metastatic leiomyoma (BML) is an extremely rare disease. Although uterine leiomyomas are benign histologically, they can metastasize to distant sites. While the incidence is very low, the lung is the organ most frequently affected by BML. Pulmonary BML usually presents as numerous well-defined nodules of various sizes, while the cavitary or cystic features in the nodules are rarely observed on radiologic images. CASE PRESENTATION: A 52-year-old woman complained of cough and dyspnea for one month...
September 12, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28894330/metastatic-pulmonary-calcification-high-resolution-computed-tomography-findings-in-23-cases
#8
Luciana Camara Belém, Carolina A Souza, Arthur Soares Souza, Dante Luiz Escuissato, Bruno Hochhegger, Luiz Felipe Nobre, Rosana Souza Rodrigues, Antônio Carlos Portugal Gomes, Claudio S Silva, Marcos Duarte Guimarães, Gláucia Zanetti, Edson Marchiori
OBJECTIVE: The aim of this study was to evaluate the high-resolution computed tomography (HRCT) findings in patients diagnosed with metastatic pulmonary calcification (MPC). MATERIALS AND METHODS: We retrospectively reviewed the HRCT findings from 23 cases of MPC [14 men, 9 women; mean age, 54.3 (range, 26-89) years]. The patients were examined between 2000 and 2014 in nine tertiary hospitals in Brazil, Chile, and Canada. Diagnoses were established by histopathologic study in 18 patients and clinical-radiological correlation in 5 patients...
July 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28892430/characterization-of-pulmonary-metastases-in-children-with-hepatoblastoma-treated-on-children-s-oncology-group-protocol-ahep0731-the-treatment-of-children-with-all-stages-of-hepatoblastoma-a-report-from-the-children-s-oncology-group
#9
Allison F O'Neill, Alexander J Towbin, Mark D Krailo, Caihong Xia, Yun Gao, M Beth McCarville, Rebecka L Meyers, Eugene D McGahren, Greg M Tiao, Stephen P Dunn, Max R Langham, Christopher B Weldon, Milton J Finegold, Sarangarajan Ranganathan, Wayne L Furman, Marcio Malogolowkin, Carlos Rodriguez-Galindo, Howard M Katzenstein
Purpose To determine whether the pattern of lung nodules in children with metastatic hepatoblastoma (HB) correlates with outcome. Methods Thirty-two patients with metastatic HB were enrolled on Children's Oncology Group Protocol AHEP0731 and treated with vincristine and irinotecan (VI). Responders to VI received two additional cycles of VI intermixed with six cycles of cisplatin/fluorouracil/vincristine/doxorubicin (C5VD), and nonresponders received six cycles of C5VD alone. Patients were imaged after every two cycles and at the conclusion of therapy...
September 11, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28890532/diffuse-idiopathic-pulmonary-neuroendocrine-cell-hyperplasia-a-case-report-and-review-of-the-literature
#10
Evangelos Koliakos, Theodoros Thomopoulos, Ziad Abbassi, Christophe Duc, Michel Christodoulou
BACKGROUND Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare pulmonary disorder that is characterized by diffuse hyperplasia of bronchiolar and bronchial pulmonary neuroendocrine cells. In this condition, when no other pathological pulmonary condition is detected, DIPNECH is considered to be an idiopathic lung disease. DIPNECH is a rare condition that can be difficult to distinguish from other forms of reactive pulmonary neuroendocrine cell hyperplasia (NECH). We present a case of DIPNECH and describe the approach to diagnosis of this rare condition...
September 11, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28885371/clinical-and-diagnostic-features-of-angiosarcoma-with-pulmonary-metastases-a-retrospective-observational-study
#11
Hanping Wang, Juhong Shi, Hongrui Liu, Yeye Chen, Yining Wang, Wenze Wang, Li Zhang
Angiosarcoma with pulmonary metastasis is a rare, fatal disease that often presents with multiple pulmonary nodules and diffuse alveolar hemorrhage. We herein review the detailed clinical characteristics of pulmonary metastatic angiosarcoma and determine a reasonable diagnostic strategy.The medical records of 11 patients with pulmonary angiosarcoma were reviewed.The mean age of the patients was 45.7 years (range, 30-71 years). All patients were male. The most common symptom was hemoptysis (8/11). Common initial misdiagnoses were tuberculosis (5/11), vasculitis (2/11), nontuberculous infectious disease (1/11), and constrictive pericarditis (1/11)...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28884037/new-insights-about-pulmonary-epithelioid-hemangioendothelioma-review-of-the-literature-and-two-case-reports
#12
Romeu Duarte Mesquita, Marta Sousa, Carmen Trinidad, Eugénia Pinto, Iosu Antón Badiola
Pulmonary epithelioid hemangioendothelioma (PEH) is a rare neoplasm of vascular origin. There are three different major imaging patterns identified in thoracic manifestation of epithelioid hemangioendothelioma: (1) multiple pulmonary nodules; (2) multiple pulmonary reticulonodular opacities; and (3) diffuse infiltrative pleural thickening. Radiographically, presence of bilateral multiple nodules is the most common pattern of presentation. The diagnosis is made on the basis of histopathological findings and confirmed by positive immunohistochemistry staining...
2017: Case Reports in Radiology
https://www.readbyqxmd.com/read/28883276/acute-exacerbation-of-organizing-pneumonia-leading-to-sudden-death-in-a-patient-with-sarcoidosis-lymphoma-syndrome
#13
Kazuhide Iizuka, Jun Ando, Azuchi Masuda, Tomonori Ochiai, Ran Tomomasa, Hajime Yasuda, Tomoiku Takaku, Yasunori Ota, Takashi Yao, Akihiko Gotoh, Norio Komatsu
The subject was an 83-year-old female; she had a history of Propionibacterium acnes-related sarcoidosis at the age of 79 years. At diagnosis, she was treated with clarithromycin and achieved remission. Four years later, during a routine physical check-up, she presented with pulmonary opacities and swelling of multiple lymph nodes. A definitive diagnosis of lymphoma could not be made by inguinal lymph node biopsy. The patient's general condition was good, and we observed her clinical course. Oh the 56th day of her illness, she died suddenly...
2017: [Rinshō Ketsueki] the Japanese Journal of Clinical Hematology
https://www.readbyqxmd.com/read/28879078/left-ventricle-and-systemic-air-embolism-after-percutaneous-lung-biopsy
#14
Juan M Galvis, David R Nunley, Teoh Zheyi, Lu Anne V Dinglasan
BACKGROUND: Systemic arterial air embolism following a percutaneous transthoracic lung biopsy is a rare but known complication, with current literature reporting an incidence of 0.01-0.45%. A prompt diagnosis of arterial air embolism is important as complications resulting from migration of air to the systemic circulation with correspondent complications. CASE REPORT: A 60-year-old female who presented for an elective percutaneous lung biopsy of an incidentally found pulmonary nodule...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28878661/the-successful-treatment-of-pulmonary-pleomorphic-carcinoma-with-pembrolizumab-a-case-report
#15
Yoko Matsumoto, Tamaki Miura, Hajime Horiuchi, Kazuhiro Usui
Pulmonary pleomorphic carcinomas are rare malignant tumors, and no standard treatments have been established. We herein report the successful treatment of a patient with pulmonary pleomorphic carcinoma with pembrolizumab. A 51-year-old man who was a current smoker presented to our hospital due to dyspnea and hemosputum. Chest X-ray showed right-sided pneumothorax with pleural effusion; chest tube drainage was therefore performed. Computed tomography after chest tube drainage showed a cavitary nodule in the right upper lobe and right hilar and bilateral mediastinal lymphadenopathy...
May 2017: Case Reports in Oncology
https://www.readbyqxmd.com/read/28872442/added-value-of-computer-aided-ct-image-features-for-early-lung-cancer-diagnosis-with-small-pulmonary-nodules-a-matched-case-control-study
#16
Peng Huang, Seyoun Park, Rongkai Yan, Junghoon Lee, Linda C Chu, Cheng T Lin, Amira Hussien, Joshua Rathmell, Brett Thomas, Chen Chen, Russell Hales, David S Ettinger, Malcolm Brock, Ping Hu, Elliot K Fishman, Edward Gabrielson, Stephen Lam
Purpose To test whether computer-aided diagnosis (CAD) approaches can increase the positive predictive value (PPV) and reduce the false-positive rate in lung cancer screening for small nodules compared with human reading by thoracic radiologists. Materials and Methods A matched case-control sample of low-dose computed tomography (CT) studies in 186 participants with 4-20-mm noncalcified lung nodules who underwent biopsy in the National Lung Screening Trial (NLST) was selected. Variables used for matching were age, sex, smoking status, chronic obstructive pulmonary disease status, body mass index, study year of the positive screening test, and screening results...
September 5, 2017: Radiology
https://www.readbyqxmd.com/read/28871800/clinicopathologic-features-of-minute-pulmonary-meningothelial-like-nodules
#17
Ayaka Asakawa, Hirotoshi Horio, Tsunekazu Hishima, Takashi Yamamichi, Masayuki Okui, Masahiko Harada
Purpose Minute pulmonary meningothelial-like nodules are incidentally discovered in lung specimens. We analyzed the clinicopathologic features of 14 cases identified in surgically resected lungs. Methods Among patients who underwent lung resection in our hospital from October 2007 to March 2016, 14 were found to have minute pulmonary meningothelial-like nodules. The clinical parameters, radiologic findings, and pathologic features of these patients were retrospectively reviewed using the medical records. Results The patients included 4 men and 10 women, with a mean age of 69 years (range 53-82 years)...
January 1, 2017: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/28871589/metastasising-leiomyoma-of-the-uterus-with-pulmonary-involvement-case-report
#18
Marta Maskey-Warzęchowska, Magdalena Chojnowska, Konrad Ptaszyński, Renata Rubinsztajn, Marzena Padzik-Moczydłowska, Rafał Krenke
Benign metastasising leiomyoma (BML) is characterised by extrauterine smooth muscle tumours in women after surgical treatment for uterine leiomyoma. Usually manifested as solitary or multiple focal lesions in various organs, it imposes a scrutinous diagnostic work-up to exclude a malignant disease and requires confirmation in microscopic examination of the extrauterine focus. The authors present a case of a 56-year-old woman with BML manifesting as bilateral multiple pulmonary nodules, with a tentative diagnosis of a disseminated malignant disease of mesenchymal origin...
2017: Advances in Respiratory Medicine
https://www.readbyqxmd.com/read/28864824/automatic-categorization-and-scoring-of-solid-part-solid-and-non-solid-pulmonary-nodules-in-ct-images-with-convolutional-neural-network
#19
Xiaoguang Tu, Mei Xie, Jingjing Gao, Zheng Ma, Daiqiang Chen, Qingfeng Wang, Samuel G Finlayson, Yangming Ou, Jie-Zhi Cheng
We present a computer-aided diagnosis system (CADx) for the automatic categorization of solid, part-solid and non-solid nodules in pulmonary computerized tomography images using a Convolutional Neural Network (CNN). Provided with only a two-dimensional region of interest (ROI) surrounding each nodule, our CNN automatically reasons from image context to discover informative computational features. As a result, no image segmentation processing is needed for further analysis of nodule attenuation, allowing our system to avoid potential errors caused by inaccurate image processing...
September 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28861589/erratum-to-ct-guided-percutaneous-trans-scapular-lung-biopsy-in-the-diagnosis-of-peripheral-pulmonary-lesion-nodules-of-the-superior-lobes-using-large-needles
#20
Alberto Rebonato, Daniele Maiettini, Marco Andolfi, Matthias J Fischer, Jacopo Vannucci, Giulio Metro, Antonio Basile, Michele Duranti, Michele Rossi
No abstract text is available yet for this article.
August 31, 2017: Cardiovascular and Interventional Radiology
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