keyword
https://read.qxmd.com/read/37902064/emerging-biomarkers-to-predict-clinical-outcomes-in-guillain-barr%C3%A3-syndrome
#21
REVIEW
Gautier Breville, Egle Sukockiene, Maria Isabel Vargas, Agustina M Lascano
INTRODUCTION: Guillain-Barré syndrome (GBS) is an immune-mediated poly(radiculo)neuropathy with a variable clinical outcome. Identifying patients who are at risk of suffering from long-term disabilities is a great challenge. Biomarkers are useful to confirm diagnosis, monitor disease progression, and predict outcome. AREAS COVERED: The authors provide an overview of the diagnostic and prognostic biomarkers for GBS, which are useful for establishing early treatment strategies and follow-up care plans...
2023: Expert Review of Neurotherapeutics
https://read.qxmd.com/read/37815138/prognostic-significance-of-carotid-and-lower-extremity-artery-stenosis-in-patients-with-high-and-very-high-cardiovascular-risk
#22
JOURNAL ARTICLE
V V Genkel, A S Kuznetsova, E V Lebedev, A O Salashenko, I I Shaposhnik
Aim      To study prognostic significance of the degree of stenosis of carotid and lower-extremity arteries (LEA) in patients at high and very high risk of cardiovascular complications (CVC).Material and methods  The study included men and women aged 40-67 years at high and very high risk of CVC. Duplex ultrasound scanning of carotid arteries and LEA was performed for all patients. Laboratory tests included measurements of glucose, glycated hemoglobin, total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides, uric acid, creatinine with estimation of glomerular filtration rate (GFR) using the CKD-EPI Creatinine Equation formula, and high-sensitivity C-reactive protein (hsCRP)...
September 30, 2023: Kardiologiia
https://read.qxmd.com/read/37815136/variability-of-measurement-and-feasibility-of-assessing-changes-in-brachiocepahlic-atherosclerotic-plaque-after-acute-coronary-syndrome
#23
JOURNAL ARTICLE
L L Bershtein, S A Boldueva, I N Kochanov, M D Lunina, T V Naiden, D S Evdokimov, B M Tandelov, P S Podmetin, E V Zbyshevskaya, V E Gumerova, E B Savinova, V H Piltakyan, S A Sayganov
Aim      Analysis of inter- and intra-study variability of changes in the atherosclerotic plaque (ASP) total height and total area, the main quantitative indexes that were planned to be used in the present study for assessment of the atherosclerotic load of carotid arteries.Material and methods  The incidence of recurrent cardiovascular complications (CVC) within 1 year after acute coronary syndrome (ACS) ranges from 7-9 % (in studies) to 34 % (in clinical practice). This indicates insufficient efficacy of traditional approaches to secondary prevention of coronary heart disease...
September 30, 2023: Kardiologiia
https://read.qxmd.com/read/37794340/effect-of-cardiac-function-in-patients-with-gastrointestinal-cancer-with-or-without-acute-kidney-injury-assessed-using-a-non-invasive-impedance-cardiography-a-case-control-study
#24
JOURNAL ARTICLE
Huihui Chen, Guolei Zhang, Lei He, Wei Zhou, Shenglei Zhang, Zhe Zhe Niu, Jingjing Jin, Mei Juan Cheng, Liping Guo, Xiang Nan Liang, Rong Fang Zhu, Huiran Zhang, Yaling Bai, Jin Sheng Xu
OBJECTIVES: This study aimed to analyze the possible causes of changes in cardiac function and investigate the feasibility of clinical assessment of gastrointestinal cancer in patients with or without acute kidney injury (AKI) assessed using a non-invasive impedance cardiography (ICG, Bioz. Cardio Dynamics, USA) to identify independent risk factors. METHODS: Patients admitted to the Fourth Hospital of Hebei Medical University, China, between May 1, 2019, and February 15, 2022, were included in this study...
October 4, 2023: BMC Cardiovascular Disorders
https://read.qxmd.com/read/37759829/novel-biomarkers-and-imaging-indices-for-the-vulnerable-patient-with-carotid-stenosis-a-single-center-study
#25
JOURNAL ARTICLE
Nikolaos Kadoglou, Konstantinos G Moulakakis, George Mantas, Aris Spathis, Evangelia Gkougkoudi, Spyridon N Mylonas, John Kakisis, Christos Liapis
BACKGROUND: We investigated the relationship of matrix metalloproteinases (MMPs), cardio-ankle vascular index (CAVI), and Gray-Scale Median (GSM) score with the severity and vulnerability of carotid atherosclerosis and major adverse cardiovascular events (MACE) during follow-up of carotid artery revascularization. METHODS: We enrolled 262 patients undergoing carotid revascularization therapy (GRT), 109 asymptomatic patients with low-grade carotid stenosis (40-70%) receiving conservative treatment (GCT), and 92 age- and sex-matched control subjects without carotid atherosclerosis (GCO)...
September 21, 2023: Biomolecules
https://read.qxmd.com/read/37699402/immune-checkpoint-inhibitor-related-myocarditis-where-we-are-and-where-we-will-go
#26
REVIEW
Andrea Vergara, Marco De Felice, Arturo Cesaro, Felice Gragnano, Ivana Pariggiano, Enrica Golia, Antonio De Pasquale, Ettore Blasi, Fabio Fimiani, Emanuele Monda, Giuseppe Limongelli, Paolo Calabrò
Immune checkpoint inhibitors (ICIs) are specific monoclonal antibodies directed against inhibitory targets of the immune system, mainly represented by programmed death-1 (PD1) ligand-1 (PD-L1) and cytotoxic T-lymphocyte antigen-4 (CTLA-4), thus enabling an amplified T-cell-mediated immune response against cancer cells. These drugs have significantly improved prognosis in patients with advanced metastatic cancer (e.g., melanoma, non-small cell lung cancer, renal cell carcinoma). However, uncontrolled activation of anti-tumor T-cells could trigger an excessive immune response, possibly responsible for multi-organ damage, including, among others, lymphocytic myocarditis...
September 12, 2023: Angiology
https://read.qxmd.com/read/37691508/-asymptomatic-course-of-rhabdomyoma-of-the-heart
#27
JOURNAL ARTICLE
S A Chepurnenko, A D Nasytko, G V Shavkuta
The article describes a clinical case of cardiac rhabdomyoma first diagnosed in an 18-year-old girl. At the age of 12 months, the patient first developed generalized, prolonged convulsive seizure with the eyeballs rolling upward, tonic arm tension, and profuse salivation. From 1.5 to 2 years, according to her mother, the girl had frequent "freezing" with fixed stare. Anticonvulsant therapy was not administered. From the age of 2 years 8 months, the child began to experience episodes of drowsiness, lethargy, blurred speech, and repeated vomiting lasting up to 2 weeks...
August 31, 2023: Kardiologiia
https://read.qxmd.com/read/37643897/sex-hormones-the-stool-microbiome-and-subclinical-atherosclerosis-in-women-with-and-without-hiv
#28
JOURNAL ARTICLE
Brandilyn A Peters, David B Hanna, Yi Wang, Kathleen M Weber, Elizabeth Topper, Allison A Appleton, Anjali Sharma, Howard N Hodis, Nanette Santoro, Chantal Guillemette, Patrick Caron, Rob Knight, Robert D Burk, Robert C Kaplan, Qibin Qi
BACKGROUND: The cardio-protective roles of endogenous estrogens may be particularly important in women with HIV, who have reduced estrogen exposure and elevated cardiovascular disease risk. The gut microbiome metabolically interacts with sex hormones, but little is known regarding how such interplay may impact cardiovascular risk. METHODS: Among 197 post-menopausal women in the Women's Interagency HIV Study, we measured 15 sex hormones in serum and assessed the gut microbiome in stool...
August 29, 2023: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/37564967/cerebrovascular-events-after-cardiovascular-surgery-diagnosis-management-and-prevention-strategies
#29
REVIEW
Maria Sabrina Ferrante, Calogera Pisano, Jérôme Van Rothem, Giovanni Ruvolo, Issam Abouliatim
INTRODUCTION: Cerebrovascular events after cardiac surgery are among the most serious complications, related to a greater risk of patient mortality. This problem can occur following the formation of gas emboli during open heart surgery. AIM: To address all the mechanisms that can lead to embolic events after cardiovascular surgery, how to manage them and how to possibly prevent them. MATERIAL AND METHODS: A search of the PubMed database was conducted...
June 2023: Polish Journal of Cardio-Thoracic Surgery
https://read.qxmd.com/read/37522824/-immune-checkpoint-inhibitors-related-cardiovascular-toxicity-3%C3%A2-mounth-follow-up
#30
JOURNAL ARTICLE
E A Kushnareva, N D Gavriluk, T N Shuginova, E L Urumova, E V Karelkina, M A Simakova, F V Moiseenko, O M Moiseeva
AIM: To analyze the condition of the cardiovascular system in oncological patients receiving immune antitumor therapy with immune checkpoint inhibitors (CPIs) based on results of laboratory and instrumental examinations during a 3-month follow-up. MATERIAL AND METHODS: This multicenter prospective observational study included 49 patients (25 men and 24 women aged 65.6±8.7 and 64.3±9.6 years, respectively). A laboratory screening (C-reactive proteins, troponin I, N-terminal pro-brain natriuretic peptide), EchoCG, and carotid ultrasound were performed for all patients...
July 28, 2023: Kardiologiia
https://read.qxmd.com/read/37460726/molecular-imaging-for-early-stage-disease-diagnosis
#31
JOURNAL ARTICLE
Kuo Zhang, Haiyan Xu, Kai Li
With the development of cellular biology, molecular biology, and other subjects, targeted molecular probe was combined with medical imaging technologies to launch a new scientific discipline of molecular imaging that is a research discipline to visualize, characterize, and analyze biological process at the cellular and molecular levels for real-time tracking and precision therapy, also termed as the medical imaging in the twenty-first century. An array of imaging techniques has been developed to image specific targets of living cells or tissues by molecular probes, including optical molecular imaging (OI), magnetic resonance molecular imaging, ultrasound (US) molecular imaging, nuclear medicine molecular imaging, X-ray molecular imaging, and multi-mode molecular imaging...
2023: Advances in Experimental Medicine and Biology
https://read.qxmd.com/read/37404202/the-safety-of-thoracic-paravertebral-block-and-erector-spinae-plane-block-in-patients-treated-with-anticoagulant-or-antiplatelet-therapy-a-narrative-review-of-the-evidence
#32
JOURNAL ARTICLE
Fulvio Nisi, Nicolò Sella, Guido DI Gregorio, Marta Lubian, Enrico Giustiniano, Giulio L Rosboch, Eleonora Balzani, Antonio Toscano, Giacomo Strano, Marco Rispoli, Domenico Massullo, Silvia Fiorelli, Domenico Santonastaso, Vanni Agnoletti, Federico Piccioni
INTRODUCTION: The management of thoracic paravertebral block (TPVB) and erector spine plane block (ESPB) in patients treated with anticoagulant or antiplatelet therapy is based on limited clinical data, mostly from single case reports. Scientific societies and organizations do not provide strong detailed indications about the limitations of these regional anesthesia techniques in patients receiving antithrombotic therapy. This review summarizes evidence regarding TPVB and ESPB in patients under antithrombotic therapy...
October 2023: Minerva Anestesiologica
https://read.qxmd.com/read/37389233/prospective-study-comparing-hepatic-steatosis-assessment-by-magnetic-resonance-imaging-and-four-ultrasound-methods-in-105-successive-patients
#33
JOURNAL ARTICLE
Remi Collin, Benoit Magnin, Constance Gaillard, Carine Nicolas, Armand Abergel, Benjamin Buchard
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is becoming a major health problem, resulting in hepatic, metabolic and cardio-vascular morbidity. AIM: To evaluate new ultrasonographic tools to detect and measure hepatic steatosis. METHODS: We prospectively included 105 patients referred to our liver unit for NAFLD suspicion or follow-up. They underwent ultrasonographic measurement of liver sound speed estimation (SSE) and attenuation coefficient (AC) using Aixplorer MACH 30 (Supersonic Imagine, France), continuous controlled attenuation parameter (cCAP) using Fibroscan (Echosens, France) and standard liver ultrasound with hepato-renal index (HRI) calculation...
June 14, 2023: World Journal of Gastroenterology: WJG
https://read.qxmd.com/read/37387070/analysis-of-non-contact-multichannel-recording-of-cardiac-vibration-visual-seismocardiogram
#34
JOURNAL ARTICLE
Deboleena Sadhukhan, Christian Dorme, Mathias Fink, Ros Kiri Ing
Seismocardiography (SCG) is the recent research focus for cardiac monitoring and diagnosis. Contact based single channel accelerometer recordings suffer from limitations due to sensor placements and propagation delay. This work uses the airborne ultrasound device named Surface Motion Camera (SMC) for non-contact multichannel recording of the chest surface vibrations and proposes visualization techniques (vSCG) to enable simultaneous evaluation of both time and spatial variations of the vibrations. Recordings are performed on 10 healthy volunteers...
June 29, 2023: Studies in Health Technology and Informatics
https://read.qxmd.com/read/37325253/-the-impact-of-statins-addind-to-the-fixed-combination-antihypertensive-therapy-on-the-arterial-stiffness-in-patients-with-moderate-and-severe-hypertension
#35
JOURNAL ARTICLE
Yuriy Sirenko, Oksana Rekovets
AIM: The objective of this study was the evaluation of the arterial stiffness, which changed after adding statins to the guidelines recommended dual or triple fixed combination antihypertensive therapy in patients with moderate to severe arterial hypertension. MATERIALS AND METHODS: It was included 99 patients in total being diagnosed with moderate and severe arterial hypertension (2nd and 3rd stages of arterial hypertension) without diabetes. Those patients were divided into 2 groups...
September 2023: Int J Cardiol Cardiovasc Risk Prev
https://read.qxmd.com/read/37280071/cerebral-blood-flow-velocity-and-oxygenation-in-neonatal-aortic-arch-repair-at-two-perfusion-temperatures
#36
JOURNAL ARTICLE
Lucy E M Finnigan, Robyn Lotto, Helen Jones, Attilio Lotto
OBJECTIVES: (i) To monitor cerebral blood flow velocity (CBFv) throughout aortic arch repair surgery and during recovery period in paediatric intensive care. (ii) To examine the relationship between near infrared spectroscopy (NIRS) and transcranial doppler ultrasound (TCD) during cardiac surgery. (iii) Examine CBFv in patients cooled to 20 °C and 25 °C. METHODS: During aortic arch repair and after surgery, TCD was monitored in 24 neonates, alongside NIRS, blood pH, pO2, pCO2, HCO3, lactate, Hb, Htc (%) and temperature (core and rectal)...
June 6, 2023: European Journal of Cardio-thoracic Surgery
https://read.qxmd.com/read/37275619/is-the-angiostrongylus-vasorum-infection-in-domestic-dogs-underestimated-or-misdiagnosed-a-comprehensive-presentation-of-four-lethal-cases
#37
JOURNAL ARTICLE
Marian Aurel Taulescu, Andrada Negoescu, Andrei Ungur, Corina Toma, Angela Monica Ionică, Claudiu Gal, Ioana Sandu, Alexandru Buzdea, Andrei Tutuneanu, Mihai Turcitu, Ioan Emilian Horvat, Georgiana Deak
INTRODUCTION: Angiostrongylus vasorum ( A. vasorum ) is a widely distributed gastropod-borne nematode, causing severe cardio-pulmonary disorders in dogs. In Romania, A. vasorum was detected in foxes and serologically confirmed in domestic dogs, but no clinical cases are currently diagnosed. METHODS: Four dogs with clinical history of respiratory distress, originating from different geographical regions of Romania, were included in the study. One dog (case 1) was clinically evaluated using thoracic radiology and cardiac ultrasound; examination of feces and PCR were also performed for the etiologic diagnosis...
2023: Frontiers in Veterinary Science
https://read.qxmd.com/read/37265695/circulating-free-t3-associates-longitudinally-with-cardio-metabolic-risk-factors-in-euthyroid-children-with-higher-tsh
#38
JOURNAL ARTICLE
Gemma Carreras-Badosa, Elsa Puerto-Carranza, Berta Mas-Parés, Ariadna Gómez-Vilarrubla, Helena Cebrià-Fondevila, Ferran Díaz-Roldán, Elena Riera-Pérez, Francis de Zegher, Lourdes Ibañez, Judit Bassols, Abel López-Bermejo
INTRODUCTION: Thyroid hormones play major roles in the regulation of body composition and metabolism, and therefore, the relationship between thyroid hormones and cardio-metabolic risk has been extensively studied in adults. In this study, we aimed to test whether free triiodothyronine (fT3) associates longitudinally with cardio-metabolic risk factors in euthyroid children. METHODS: A prospective study cohort of 599 apparently healthy school-age children were assessed at baseline (mean age 8...
2023: Frontiers in Endocrinology
https://read.qxmd.com/read/37251448/point-of-care-ultrasound-findings-in-critically-ill-sars-cov2-patients-in-an-hiv-endemic-resourced-constrained-setting
#39
JOURNAL ARTICLE
Willem Marcelle Jagga, Bruce Biccard, Jenique Bailly, Ali Esmail, Katherine Antel, Jessica Opie
OBJECTIVES: To describe the incidence of venous thromboembolism (VTE) in mechanically ventilated COVID-19 patients in an HIV endemic, resourced constrained setting. To describe the incidence of VTE in relation to HIV status and anticoagulant therapy, and to evaluate VTE-associated cardio-respiratory changes. To establish the contribution of HIV, anticoagulation therapy and other risk factors to mortality. DESIGN: Prospective descriptive study. SETTING: Single-center tertiary teaching hospital...
June 2023: Heliyon
https://read.qxmd.com/read/37222187/neonatal-diagnosis-of-circumferential-skin-creases
#40
Chiara Cauzzo, Valentina Chiavaroli, Chiara Palka Bayard de Volo, Altea Petrucci, Teresa Topazio, Giulia Di Donato, Riccardo Fiorentino, Francesco Chiarelli, Susanna Di Valerio
BACKGROUND: Circumferential skin creases is a rare and heterogeneous disorder characterized by multiple and redundant skin folds, which can present as an isolated feature or in association with other phenotypic anomalies. Here, we report the case of a newborn who immediately captured our attention because of his phenotype. CASE: A male Caucasian infant was born at 39 weeks and 4 days of gestational age with an instrumental delivery, after a pregnancy characterized by threat of preterm birth at 32 weeks...
May 24, 2023: Birth Defects Research
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