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https://www.readbyqxmd.com/read/28728854/potential-use-of-american-college-of-radiology-bi-rads-mammography-atlas-for-reporting-and-assessing-lesions-detected-on-dedicated-breast-ct-imaging-preliminary-study
#1
Hae Kyoung Jung, Cherie M Kuzmiak, Keum Won Kim, Na Mi Choi, Hye Jeong Kim, Eun Lee Langman, Sora Yoon, Doreen Steen, Donglin Zeng, Fei Gao
RATIONALE AND OBJECTIVES: Dedicated breast computed tomography (DBCT) is an emerging and promising modality for breast lesions. The objective of this study was to evaluate the potential use of applying the BI-RADS Mammography Atlas 5th Edition for reporting and assessing breast lesions on DBCT. Currently, no atlas exists for DBCT. MATERIALS AND METHODS: Four radiologists trained in breast imaging were recruited in this institutional review board-approved, Health Insurance Portability and Accountability Act-compliant study...
July 17, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28726117/applying-a-new-bilateral-mammographic-density-segmentation-method-to-improve-accuracy-of-breast-cancer-risk-prediction
#2
Shiju Yan, Yunzhi Wang, Faranak Aghaei, Yuchen Qiu, Bin Zheng
PURPOSE: How to optimally detect bilateral mammographic asymmetry and improve risk prediction accuracy remains a difficult and unsolved issue. Our aim was to find an effective mammographic density segmentation method to improve accuracy of breast cancer risk prediction. METHODS: A dataset including 168 negative mammography screening cases was used. We applied a mutual threshold to bilateral mammograms of left and right breasts to segment the dense breast regions...
July 19, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28725051/mammographic-density-blood-telomere-length-and-lipid-peroxidation
#3
Natalie J Erdmann, Lea A Harrington, Lisa J Martin
Extensive mammographic density is a strong risk factor for breast cancer, but may also be an indicator of biological age. In this study we examined whether mammographic density is related to blood telomere length, a potential marker of susceptibility to age-related disease. We measured mammographic density by a computer assisted method and blood telomere length using a validated PCR method. Urinary malondialdehyde (MDA), a marker of lipid peroxidation, was measured in 24 hour urine collections. In the 342 women examined telomere length was negatively correlated with age, was lower in postmenopausal compared to premenopausal women and in smokers compared to non-smokers, and was positively correlated with urinary MDA...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28719794/associations-of-breast-density-with-demographic-reproductive-and-lifestyle-factors-in-a-developing-southeast-asian-population
#4
Phuong Dung Yun Trieu, Claudia Mello-Thoms, Jennifer K Peat, Thuan Doan Do, Patrick C Brennan
The aim of this study was to investigate how breast density interacted with demographic, reproductive, and lifestyle features among Vietnamese women. Mammographic density and established risk factors for breast cancer were collected from 1651 women (345 cancer cases and 1306 normal cases) in Vietnam. The association of breast density categories with potential risk factors was investigated using Spearman's test for continuous variables and χ(2) tests for categorical variables. Independent factors associated with high breast density and breast cancer in specific density groupings were assessed using logistic regression...
July 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28707989/breast-density-scales-the-metric-matters
#5
Mohamed Abdolell, Kaitlyn M Tsuruda, Peter Brown, Judy Caines, Sian Iles
OBJECTIVE: Measures of percent mammographic density (PMD) are often categorized using various density scales. The purpose of this study was to examine information loss associated with the use of categorical density scales. METHODS: Baseline PMD was assessed at 1% precision for 2,374 women. The data were used to create 21-category, 4-category and 2-category density scales. R-squared and root mean square error (RMSE) were used to evaluate the effect of categorizing PMD...
July 14, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28702896/breast-cancer-risk-prediction-an-update-to-the-rosner-colditz-breast-cancer-incidence-model
#6
Megan S Rice, Shelley S Tworoger, Susan E Hankinson, Rulla M Tamimi, A Heather Eliassen, Walter C Willett, Graham Colditz, Bernard Rosner
PURPOSE: To update and expand the Rosner-Colditz breast cancer incidence model by evaluating the contributions of more recently identified risk factors as well as predicted percent mammographic density (MD) to breast cancer risk. METHODS: Using data from the Nurses' Health Study (NHS) and NHSII, we added adolescent somatotype (9 unit scale), vegetable intake (servings/day), breastfeeding (months), physical activity (MET-h/week), and predicted percent MD to the Rosner-Colditz model to determine whether these variables improved model discrimination...
July 12, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28702890/adiposity-during-early-adulthood-changes-in-adiposity-during-adulthood-attained-adiposity-and-mammographic-density-among-premenopausal-women
#7
Aliya Alimujiang, Catherine Appleton, Graham A Colditz, Adetunji T Toriola
PURPOSE: We investigated the associations of adolescent adiposity, changes in adiposity during adulthood, and attained adiposity with volumetric mammographic density measures. METHODS: We recruited 383 premenopausal women who had a routine screening mammogram at the Breast Health Center, Washington University in St. Louis, MO from December 2015 to October 2016. Trained research personnel assessed current adiposity measures. Weight at ages 18 and 30 were self-reported...
July 12, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28700125/optical-assessment-of-mammographic-breast-density-by-a-12-wavelength-versus-a-continuous-spectrum-optical-spectroscopy-device
#8
E Jane Walter, Lothar Lilge
A 12-laser-wavelength, fixed source-detector position, cup-based optical breast spectroscopy (OBS) device was developed for use in large-scale, multi-center trials as a mammographic breast density (MBD) quantification and breast cancer risk pre-screening tool. In this study, the device was evaluated in comparison with a spectrometer-based device used in previous studies. The devices were compared on their ability to predict mammographic percent density (MPD) and to identify women with high MBD from optical spectra...
July 12, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/28698185/age-at-menarche-and-late-adolescent-adiposity-associated-with-mammographic-density-on-processed-digital-mammograms-in-24-840-women
#9
Stacey E Alexeeff, Nnaemeka Odo, Jafi A Lipson, Ninah Achacoso, Joseph H Rothstein, Martin J Yaffe, Rhea Y Liang, Luana Acton, Valerie McGuire, Alice S Whitmore, Daniel L Rubin, Weiva Sieh, Laurel A Habel
BACKGROUND: High mammographic density is strongly associated with increased breast cancer risk. Some, but not all, risk factors for breast cancer are also associated with higher mammographic density. METHODS: The study cohort (N=24,840) was drawn from the Research Program in Genes, Environment and Health of Kaiser Permanente Northern California and included non-Hispanic white females aged 40-74 years with a full-field digital mammogram (FFDM). Percent density (PD) and dense area (DA) were measured by a radiological technologist using Cumulus...
July 11, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28698184/the-association-of-mammographic-density-and-molecular-breast-cancer-subtype
#10
Brandy L Edwards, Kristen A Atkins, George J Stukenborg, Wendy M Novicoff, Krista N Larson, Wendy F Cohn, Jennifer A Harvey, Anneke T Schroen
BACKGROUND: Mammographic density (MD) is associated with increased breast cancer (BC) risk, yet limited data exists on an association between MD and BC molecular subtypes. METHODS: Women 18 years and older with BC and available mammograms between 2003-2012 were enrolled in a larger study on MD. MD was classified by Breast Imaging Reporting and Data System (BI-RADS) classification and by volumetric breast percent density (Volpara SolutionsTM). Subtype was assigned by hormone receptor-status, tumor grade and mitotic score (MS)...
July 11, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28697417/tumor-characteristics-and-family-history-in-relation-to-mammographic-density-and-breast-cancer-the-french-e3n-cohort
#11
Gertraud Maskarinec, Laureen Dartois, Suzette Delaloge, John Hopper, Françoise Clavel-Chapelon, Laura Baglietto
BACKGROUND: Mammographic density is a known heritable risk factor for breast cancer, but reports how tumor characteristics and family history may modify this association are inconsistent. METHODS: Dense and total breast areas were assessed using Cumulus™ from pre-diagnostic mammograms for 820 invasive breast cancer cases and 820 matched controls nested within the French E3N cohort study. To allow comparisons across models, percent mammographic density (PMD) was standardized to the distribution of the controls...
July 8, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28677026/circulating-leptin-and-adiponectin-and-breast-density-in-premenopausal-mexican-women-the-mexican-teachers-cohort
#12
L Dossus, S Rinaldi, C Biessy, M Hernandez, M Lajous, A Monge, E Ortiz-Panozo, E Yunes, R Lopez-Ridaura, G Torres-Mejía, I Romieu
PURPOSE: Leptin and adiponectin are produced by the adipose tissue. Mammographic density (MD) is one of the strongest predictors of breast cancer (BC) and is highly influenced by adiposity. How the interplay between MD, obesity, and obesity-related biomarkers influences BC risk, however, is still unknown, especially in premenopausal women, where adiposity seems to be protective for BC. The aim of the present study was to explore the association between circulating leptin, adiponectin, and their ratio, with MD in Mexican premenopausal women who are part of the large Mexican Teachers' Cohort (MTC)...
July 4, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28668405/local-breast-density-assessment-using-reacquired-mammographic-images
#13
Eloy García, Oliver Diaz, Robert Martí, Yago Diez, Albert Gubern-Mérida, Melcior Sentís, Joan Martí, Arnau Oliver
PURPOSE: The aim of this paper is to evaluate the spatial glandular volumetric tissue distribution as well as the density measures provided by Volpara™ using a dataset composed of repeated pairs of mammograms, where each pair was acquired in a short time frame and in a slightly changed position of the breast. MATERIALS AND METHODS: We conducted a retrospective analysis of 99 pairs of repeatedly acquired full-field digital mammograms from 99 different patients...
August 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28666001/mammographic-density-and-ageing-a-collaborative-pooled-analysis-of-cross-sectional-data-from-22-countries-worldwide
#14
Anya Burton, Gertraud Maskarinec, Beatriz Perez-Gomez, Celine Vachon, Hui Miao, Martín Lajous, Ruy López-Ridaura, Megan Rice, Ana Pereira, Maria Luisa Garmendia, Rulla M Tamimi, Kimberly Bertrand, Ava Kwong, Giske Ursin, Eunjung Lee, Samera A Qureshi, Huiyan Ma, Sarah Vinnicombe, Sue Moss, Steve Allen, Rose Ndumia, Sudhir Vinayak, Soo-Hwang Teo, Shivaani Mariapun, Farhana Fadzli, Beata Peplonska, Agnieszka Bukowska, Chisato Nagata, Jennifer Stone, John Hopper, Graham Giles, Vahit Ozmen, Mustafa Erkin Aribal, Joachim Schüz, Carla H Van Gils, Johanna O P Wanders, Reza Sirous, Mehri Sirous, John Hipwell, Jisun Kim, Jong Won Lee, Caroline Dickens, Mikael Hartman, Kee-Seng Chia, Christopher Scott, Anna M Chiarelli, Linda Linton, Marina Pollan, Anath Arzee Flugelman, Dorria Salem, Rasha Kamal, Norman Boyd, Isabel Dos-Santos-Silva, Valerie McCormack
BACKGROUND: Mammographic density (MD) is one of the strongest breast cancer risk factors. Its age-related characteristics have been studied in women in western countries, but whether these associations apply to women worldwide is not known. METHODS AND FINDINGS: We examined cross-sectional differences in MD by age and menopausal status in over 11,000 breast-cancer-free women aged 35-85 years, from 40 ethnicity- and location-specific population groups across 22 countries in the International Consortium on Mammographic Density (ICMD)...
June 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28660430/mammographic-breast-density-decreases-after-bariatric-surgery
#15
Austin D Williams, Alycia So, Marie Synnestvedt, Colleen M Tewksbury, Despina Kontos, Meng-Kang Hsiehm, Lauren Pantalone, Emily F Conant, Mitchell Schnall, Kristoffel Dumon, Noel Williams, Julia Tchou
PURPOSE: Breast density (BD), an important risk factor for breast cancer, can change over time in some women, but the underlying mechanism is unclear. Very little is known about the impact of surgical weight loss on BD. Our hypothesis is that weight loss after bariatric surgery is associated with a significant and favorable change in mammographic BD. METHODS: We identified 1097 women 40 years of age or older who underwent gastric bypass or sleeve gastrectomy at our institution from 2010 to 2014...
June 28, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28657850/comparison-of-visual-assessment-of-breast-density-in-bi-rads-4th-and-5th-editions-with-automated-volumetric-measurement
#16
Ji Hyun Youk, So Jung Kim, Eun Ju Son, Hye Mi Gweon, Jeong-Ah Kim
OBJECTIVE: The purpose of this study was to compare visual assessments of mammographic breast density by radiologists using BI-RADS 4th and 5th editions in correlation with automated volumetric breast density measurements. MATERIALS AND METHODS: A total of 337 consecutive full-field digital mammographic examinations with standard views were retrospectively assessed by two radiologists for mammographic breast density according to BI-RADS 4th and 5th editions. Fully automated measurement of the volume of fibroglandular tissue and total breast and percentage breast density was performed with a commercially available software program...
June 28, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28656638/new-york-state-breast-density-mandate-follow-up-data-with-screening-sonography
#17
Stamatia Destounis, Andrea Arieno, Renee Morgan
OBJECTIVES: To evaluate the impact on breast cancer detection from screening breast sonography performed in women with mammographically dense breasts. METHODS: This study used a retrospective chart review. Data collected included total number of screening mammograms, total number of dense breast screening sonograms, total number of procedures performed, biopsy results, and demographic data. Data were obtained from January 1, 2013, through August 31, 2015. During this period, there were a total of 195,982 screening mammographic examinations performed at our facility...
June 28, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28633324/mammographic-density-reduction-as-a-prognostic-marker-for-postmenopausal-breast-cancer-results-using-a-joint-longitudinal-survival-modelling-approach
#18
Therese M-L Andersson, Michael J Crowther, Kamila Czene, Per Hall, Keith Humphreys
Previous studies have linked reductions in mammographic density after a breast cancer diagnosis to an improved prognosis. These studies focused on short-term change, using a two-stage process, treating estimated change as a fixed covariate in a survival model. We propose the use of a joint longitudinal-survival model. This enables us to model long-term trends in density while accounting for drop-out as well as for measurement error. We study the change in mammographic density after a breast cancer diagnosis and its association with prognosis (measured by cause-specific mortality), overall and with respect to hormone replacement therapy and tamoxifen treatment...
June 13, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28624977/interaction-of-mammographic-breast-density-with-menopausal-status-and-postmenopausal-hormone-use-in-relation-to-the-risk-of-aggressive-breast-cancer-subtypes
#19
Lusine Yaghjyan, Rulla M Tamimi, Kimberly A Bertrand, Christopher G Scott, Matthew R Jensen, V Shane Pankratz, Kathy Brandt, Daniel Visscher, Aaron Norman, Fergus Couch, John Shepherd, Bo Fan, Yunn-Yi Chen, Lin Ma, Andrew H Beck, Steven R Cummings, Karla Kerlikowske, Celine M Vachon
PURPOSE: We examined the associations of mammographic breast density with breast cancer risk by tumor aggressiveness and by menopausal status and current postmenopausal hormone therapy. METHODS: This study included 2596 invasive breast cancer cases and 4059 controls selected from participants of four nested case-control studies within four established cohorts: the Mayo Mammography Health Study, the Nurses' Health Study, Nurses' Health Study II, and San Francisco Mammography Registry...
June 17, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28621548/an-investigation-into-the-mammographic-appearances-of-missed-breast-cancers-when-recall-rates-are-reduced
#20
Norhashimah Mohd Norsuddin, Claudia Mello-Thoms, Warren Reed, Mary Rickard, Sarah Lewis
OBJECTIVES: This study investigated whether certain mammographic appearances of breast cancer are missed when radiologists read at lower recall rates. METHODS: Five radiologists read one identical test set of 200 mammographic (180 normal cases and 20 abnormal cases) three times and were requested to adhere to three different recall rate conditions: free recall, 15% and 10%. The radiologists were asked to mark the locations of suspicious lesions and provide a confidence rating for each decision...
June 16, 2017: British Journal of Radiology
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