keyword
MENU ▼
Read by QxMD icon Read
search

mammographic density

keyword
https://www.readbyqxmd.com/read/28515107/a-randomized-double-blind-placebo-controlled-trial-of-the-effect-of-vitamin-d3-supplementation-on-breast-density-in-premenopausal-women
#1
Jacques Brisson, Sylvie Bérubé, Caroline Diorio, Benoit Masse, Julie Lemieux, Thierry Duchesne, Edgar Delvin, Reinhold Vieth, Martin J Yaffe, Jocelyne Chiquette
BACKGROUND: This double-blind, placebo-controlled parallel-group trial assessed whether oral supplementation with 1,000, 2,000 or 3,000 IU/day vitamin D3 over one year reduces percent mammographic breast density in premenopausal women. METHODS: The trial was conducted between October 2012 and June 2015, among premenopausal female volunteers from Quebec City (Quebec, Canada). Women were randomized with ratio 1:1:1:1 to one of four study arms (1,000, 2,000 or 3,000 IU/d vitamin D3 or placebo)...
May 17, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28512241/assessment-of-breast-cancer-risk-factors-reveals-subtype-heterogeneity
#2
Johanna Holm, Louise Eriksson, Alexander Ploner, Mikael Eriksson, Mattias Rantalainen, Jingmei Li, Per Hall, Kamila Czene
Subtype heterogeneity for breast cancer risk factors has been suspected, potentially reflecting etiological differences and implicating risk prediction. However, reports are conflicting regarding presence of heterogeneity for many exposures. To examine subtype heterogeneity across known breast cancer risk factors, we conducted a case-control analysis of 2,632 breast cancers and 15,945 controls in Sweden. Molecular subtype was predicted from pathology-record derived immunohistochemistry markers by a classifier trained on PAM50 subtyping...
May 16, 2017: Cancer Research
https://www.readbyqxmd.com/read/28495213/breast-density-legislation-in-new-england-a-survey-study-of-practicing-radiologists
#3
Ana P Lourenco, Roberta M DiFlorio-Alexander, Priscilla J Slanetz
RATIONALE AND OBJECTIVES: This study aimed to assess radiologists' knowledge about breast density legislation as well as perceived practice changes resulting from the enactment of breast density legislation. MATERIALS AND METHODS: This is an institutional review board-exempt anonymous email survey of 523 members of the New England Roentgen Ray Society. In addition to radiologist demographics, survey questions addressed radiologist knowledge of breast density legislation, knowledge of breast density as a risk factor for breast cancer, recommendations for supplemental screening, and perceived practice changes resulting from density notification legislation...
May 8, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28489877/low-back-pain-in-healthy-postmenopausal-women-and-the-effect-of-physical-activity-a-secondary-analysis-in-a-randomized-trial
#4
Mirca Marini, Benedetta Bendinelli, Melania Assedi, Daniela Occhini, Maria Castaldo, Jacopo Fabiano, Marco Petranelli, Mario Migliolo, Marco Monaci, Giovanna Masala
Epidemiological studies on the prevalence of musculoskeletal pain have consistently shown that this is a relevant health problem, with non-specific low back pain (LBP) being the most commonly reported in adult females. Conflicting data on the association between LBP symptoms and physical activity (PA) have been reported. Here, we investigated the prevalence of LBP and the effect of a 24-month non-specific PA intervention on changes in LBP prevalence in a series of Italian healthy postmenopausal women. We performed a secondary analysis in the frame of the DAMA trial, a factorial randomized intervention trial aimed to evaluate the ability of a 24-month intervention, based on moderate-intensity PA, and/or dietary modification, in reducing mammographic breast density in healthy postmenopausal women...
2017: PloS One
https://www.readbyqxmd.com/read/28473194/association-of-catechol-o-methyltransferase-polymorphism-val158met-and-mammographic-density-a-meta-analysis
#5
Roope A Kallionpää, Elina Uusitalo, Juha Peltonen
OBJECTIVES: The Val158Met polymorphism in catechol-O-methyltransferase (COMT) enzyme reduces the methylation of catechol estrogens, which may affect mammographic density. High mammographic density is a known risk factor of breast cancer. Our aim was to perform meta-analysis of the effect of COMT Val158Met polymorphism on mammographic density. METHODS: Original studies reporting data on mammographic density, stratified by the presence of COMT Val158Met polymorphism, were identified and combined using genetic models Met/Val vs...
May 1, 2017: Gene
https://www.readbyqxmd.com/read/28464481/correlation-of-mammographic-density-and-serum-calcium-levels-in-patients-with-primary-breast-cancer
#6
Carolin C Hack, Martin J Stoll, Sebastian M Jud, Katharina Heusinger, Werner Adler, Lothar Haeberle, Thomas Ganslandt, Felix Heindl, Rüdiger Schulz-Wendtland, Alexander Cavallaro, Michael Uder, Matthias W Beckmann, Peter A Fasching, Christian M Bayer
Percentage mammographic breast density (PMD) is one of the most important risk factors for breast cancer (BC). Calcium, vitamin D, bisphosphonates, and denosumab have been considered and partly confirmed as factors potentially influencing the risk of BC. This retrospective observational study investigated the association between serum calcium level and PMD. A total of 982 BC patients identified in the research database at the University Breast Center for Franconia with unilateral BC, calcium and albumin values, and mammogram at the time of first diagnosis were included...
May 2, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28458473/screening-methods-clinical-breast-examination-and-mammography-to-detect-breast-cancer-in-women-aged-40-49-years
#7
Navneet Takkar, Suman Kochhar, Priyanka Garg, A K Pandey, Usha Rani Dalal, Uma Handa
OBJECTIVE: The aim of this study is to detect breast cancer rate, nodal status, tumor size, and associated risk factors using clinical breast examination (CBE) and mammography as screening tools in women aged 40-49 years. MATERIALS AND METHODS: A total of 500 women were screened in a time period of 2 years, between the ages of 40-49 years for breast cancer. Screening tools used were CBE and mammography. Clinical history and risk factors related to breast cancer were recorded...
January 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28456099/thyroid-disorders-and-mammographic-density-in-spanish-women-var-ddm-study
#8
Ana María Pedraza-Flechas, Virginia Lope, Carmen Vidal, Carmen Sánchez-Contador, Carmen Santamariña, Carmen Pedraz-Pingarrón, Pilar Moreo, Nieves Ascunce, Josefa Miranda-García, Rafael Llobet, Nuria Aragonés, Dolores Salas-Trejo, Marina Pollán, Beatriz Pérez-Gómez
OBJECTIVES: The association between breast cancer (BC) and thyroid disorders has been widely explored with unclear results. Mammographic density (MD) is one of the strongest risk factor for BC. This study explores the relationship between thyroid diseases and MD in Spanish women. MATERIALS & METHODS: This cross-sectional study covered 2883 women aged 47-71 years participating in 7 BC screening programs in 2010. They allowed access to their mammograms, had anthropometrical-measures taken, and answered a telephonic epidemiological interview which included specific questions on thyroid diseases...
April 26, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28446127/sample-size-and-power-determination-when-limited-preliminary-information-is-available
#9
Christine E McLaren, Wen-Pin Chen, Thomas D O'Sullivan, Daniel L Gillen, Min-Ying Su, Jeon H Chen, Bruce J Tromberg
BACKGROUND: We describe a novel strategy for power and sample size determination developed for studies utilizing investigational technologies with limited available preliminary data, specifically of imaging biomarkers. We evaluated diffuse optical spectroscopic imaging (DOSI), an experimental noninvasive imaging technique that may be capable of assessing changes in mammographic density. Because there is significant evidence that tamoxifen treatment is more effective at reducing breast cancer risk when accompanied by a reduction of breast density, we designed a study to assess the changes from baseline in DOSI imaging biomarkers that may reflect fluctuations in breast density in premenopausal women receiving tamoxifen...
April 26, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28442393/progesterone-receptors-pr-mediate-stat-actions-pr-and-prolactin-receptor-signaling-crosstalk-in-breast-cancer-models
#10
Katherine A Leehy, Thu H Truong, Laura J Mauro, Carol A Lange
Estrogen is the major mitogenic stimulus of mammary gland development during puberty wherein ER signaling acts to induce abundant PR expression. PR signaling, in contrast, is the primary driver of mammary epithelial cell proliferation in adulthood. The high circulating levels of progesterone during pregnancy signal through PR, inducing expression of the prolactin receptor (PRLR). Cooperation between PR and prolactin (PRL) signaling, via regulation of downstream components in the PRL signaling pathway including JAKs and STATs, facilitates the alveolar morphogenesis observed during pregnancy...
April 22, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28440226/calibration-phantoms-for-accurate-water-and-lipid-density-quantification-using-dual-energy-mammography
#11
H-M Cho, H Ding, N Kumar, D Sennung, S Molloi
The aim of this study is to investigate the feasibility of water and lipid as calibration phantoms for accurate dual energy breast density quantification. Dual energy calibration was performed on a mammography system based on scanning multi-slit Si strip photon-counting detectors using plastic water and adipose-equivalent phantoms as the basis materials. Two different methods were used to convert the dual energy decomposition measurements in plastic phantom thicknesses into the true water and lipid basis materials...
April 25, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28420325/usefulness-of-grayscale-inverted-images-in-addition-to-standard-images-in-digital-mammography
#12
Ayşegül Altunkeser, M Kazım Körez
BACKGROUND: Mammography is essential for early diagnosis of breast cancer, which is the most common type of cancer in females that is associated with a high mortality rate. We investigated whether evaluation of the grayscale inverted images of mammograms would aid in increasing the diagnostic sensitivity of the mammographic imaging technique. METHODS: Our study included 636 mammograms of 159 women who had undergone digital mammography. Standard, grayscale inverted, and standard plus grayscale inverted images were sequentially examined three times, at 15-day intervals, for the presence or assessment of pathological changes in the skin, calcification, asymmetric density, mass lesions, structural distortions, and intramammary and axillary lymph nodes...
April 18, 2017: BMC Medical Imaging
https://www.readbyqxmd.com/read/28419125/mammographic-compression-in-asian-women
#13
Susie Lau, Yang Faridah Abdul Aziz, Kwan Hoong Ng
OBJECTIVES: To investigate: (1) the variability of mammographic compression parameters amongst Asian women; and (2) the effects of reducing compression force on image quality and mean glandular dose (MGD) in Asian women based on phantom study. METHODS: We retrospectively collected 15818 raw digital mammograms from 3772 Asian women aged 35-80 years who underwent screening or diagnostic mammography between Jan 2012 and Dec 2014 at our center. The mammograms were processed using a volumetric breast density (VBD) measurement software (Volpara) to assess compression force, compression pressure, compressed breast thickness (CBT), breast volume, VBD and MGD against breast contact area...
2017: PloS One
https://www.readbyqxmd.com/read/28415974/evaluation-of-the-association-between-quantitative-mammographic-density-and-breast-cancer-occurred-in-different-quadrants
#14
Siwa Chan, Jeon-Hor Chen, Shunshan Li, Rita Chang, Darh-Cherng Yeh, Ruey-Feng Chang, Lee-Ren Yeh, Jessica Kwong, Min-Ying Su
BACKGROUND: To investigate the relationship between mammographic density measured in four quadrants of a breast with the location of the occurred cancer. METHODS: One hundred and ten women diagnosed with unilateral breast cancer that could be determined in one specific breast quadrant were retrospectively studied. Women with previous cancer/breast surgery were excluded. The craniocaudal (CC) and mediolateral oblique (MLO) mammography of the contralateral normal breast were used to separate a breast into 4 quadrants: Upper-Outer (UO), Upper-Inner (UI), Lower-Outer (LO), and Lower-Inner (LI)...
April 17, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28415815/bi-rads-3-5-microcalcifications-prediction-of-lymph-node-metastasis-of-breast-cancer
#15
Dongzhi Cen, Li Xu, Siwei Zhang, Shuqin Zhou, Yan Huang, Zhiguang Chen, Ningna Li, Yuan Wang, Qun Wang
PURPOSE: To determine whether the clinicopathological parameters and Breast Imaging Reporting and Data System (BI-RADS) 3-5 microcalcifications differed between lymph node positive (LN (+)) and lymph node negative (LN (-)) invasive ductal carcinoma (IDC). RESULTS: For microcalcification-associated breast cancers, seven selected features (age, tumor size, Ki-67 status, lymphovascular invasion, calcification range, calcification diameter and calcification density) were significantly associated with LN status (all P < 0...
May 2, 2017: Oncotarget
https://www.readbyqxmd.com/read/28409837/clinical-accuracy-of-preoperative-breast-mri-for-breast-cancer
#16
Jennifer Tseng, Alexandra Kyrillos, Erik Liederbach, Georgia G Spear, Jacob Ecanow, Chi-Hsiung Wang, Tom Czechura, Olga Kantor, Megan Miller, David J Winchester, Catherine E Pesce, Sarah Rabbitt, Katharine Yao
BACKGROUND: It is unclear if breast magnetic resonance imaging (MRI) is more accurate than mammography (MGM) and ultrasound (U/S) in aggregate for patients with invasive cancer. METHODS: We compared concordance of combined tumor size and tumor foci between MRI and MGM and U/S combined to pathological tumor size and foci as the gold standard from 2009 to 2015. Tumor size was nonconcordant if it differed from the pathologic size by ≥33% and tumor foci was nonconcordant if >1 foci were seen...
April 13, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28392579/mammographic-density-and-vitamin-d-levels-a-cross-sectional-study
#17
Loreen Straub, Johanna Riedel, Peter B Luppa, Johanna Wissing, Almut Artmann, Marion Kiechle, Vanadin Regina Seifert-Klauss
Background Some studies have already proposed an inverse association between vitamin D levels and breast density. As breast density is already considered an established risk factor for breast cancer, such a connection could offer a new starting point for the prevention of breast cancer. Material and Methods To investigate this suggested connection, a total of 412 pre- and 572 post-menopausal women for whom mammography was indicated were recruited into this cross-sectional study. In addition to a questionnaire-based interview on the patient's general and gynecological medical history, her eating habits and lifestyle, serum levels of 25-hydroxyvitamin D [25(OH)D], calcium, phosphate and creatinine were determined...
March 2017: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/28391726/determinants-of-percent-mammographic-density-in-women-with-premature-ovarian-insufficiency
#18
F R Torelli, M F Brancalion, D A Yela, C L Benetti-Pinto
OBJECTIVE: To evaluate the determinants of breast density in women with premature ovarian insufficiency (POI). METHODS: In a cross-sectional study of 163 women with POI undergoing mammography, percent mammographic density (PMD) was evaluated by digitizing the image. PMD was correlated with age, age at menarche, age at POI, time since POI, body mass index (BMI), gestational history and hormone therapy (HT) use (duration, dose, regimen). RESULTS: POI was diagnosed at a mean age of 32...
April 9, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28381271/association-between-air-pollution-and-mammographic-breast-density-in-the-breast-cancer-surveilance-consortium
#19
Lusine Yaghjyan, Robert Arao, Cole Brokamp, Ellen S O'Meara, Brian L Sprague, Gabriela Ghita, Patrick Ryan
BACKGROUND: Mammographic breast density is a well-established strong risk factor for breast cancer. The environmental contributors to geographic variation in breast density in urban and rural areas are poorly understood. We examined the association between breast density and exposure to ambient air pollutants (particulate matter <2.5 μm in diameter (PM2.5) and ozone (O3)) in a large population-based screening registry. METHODS: Participants included women undergoing mammography screening at imaging facilities within the Breast Cancer Surveillance Consortium (2001-2009)...
April 6, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/28376632/mammographic-density-as-a-risk-factor-to-go-out-of-a-30-year-fog
#20
Catherine Colin, Anne-Marie Schott-Pethelaz
No abstract text is available yet for this article.
January 1, 2017: Acta Radiologica
keyword
keyword
75014
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"