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https://www.readbyqxmd.com/read/29330415/unusual-multiscale-mechanics-of-biomimetic-nanoparticle-hydrogels
#1
Yunlong Zhou, Pablo F Damasceno, Bagganahalli S Somashekar, Michael Engel, Falin Tian, Jian Zhu, Rui Huang, Kyle Johnson, Carl McIntyre, Kai Sun, Ming Yang, Peter F Green, Ayyalusamy Ramamoorthy, Sharon C Glotzer, Nicholas A Kotov
Viscoelastic properties are central for gels and other materials. Simultaneously, high storage and loss moduli are difficult to attain due to their contrarian requirements to chemical structure. Biomimetic inorganic nanoparticles offer a promising toolbox for multiscale engineering of gel mechanics, but a conceptual framework for their molecular, nanoscale, mesoscale, and microscale engineering as viscoelastic materials is absent. Here we show nanoparticle gels with simultaneously high storage and loss moduli from CdTe nanoparticles...
January 12, 2018: Nature Communications
https://www.readbyqxmd.com/read/29330182/fluorescence-recovery-allows-the-implementation-of-a-fluorescence-reporter-gene-platform-applicable-for-the-detection-and-quantification-of-horizontal-gene-transfer-in-anoxic-environments
#2
Rafael Pinilla, Leise Riber, Søren J Sørensen
The study of horizontal gene transfer (HGT) in microbial communities has been revolutionized by significant advances in cultivation-independent methods based on fluorescence reporter gene technologies. Recently, the combination of these novel approaches with flow cytometry has presented itself as one of the most powerful tools to study the spread of mobile genetic elements (MGEs) in the environment. However, the use of fluorescent markers like green fluorescent protein (GFP) and mCherry is limited by environmental constraints that affect the correct maturation of their fluorophores, such as oxygen availability and pH levels...
January 12, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29329992/eus-elastography-strain-ratio-and-fractal-based-quantitative-analysis-for-the-diagnosis-of-solid-pancreatic-lesions
#3
Silvia Carrara, Milena Di Leo, Fabio Grizzi, Loredana Correale, Rahal Daoud, Andrea Anderloni, Francesco Auriemma, Alessandro Fugazza, Paoletta Preatoni, Roberta Maselli, Cesare Hassan, Elena Finati, Benedetto Mangiavillano, Alessandro Repici
BACKGROUND AND AIMS: EUS elastography is useful in characterizing solid pancreatic lesions (SPLs), and fractal analysis-based technology has been used to evaluate geometric complexity in oncology. The aim of this study was to evaluate EUS elastography (strain ratio) and fractal analysis for the characterization of SPLs. METHODS: Consecutive patients with SPLs were prospectively enrolled between December 2015 and February 2017. Elastographic evaluation included parenchymal strain ratio (pSR) and wall strain ratio (wSR) and was performed with the EU-ME2 processor (Olympus)...
January 9, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29327394/photothermal-responsive-conjugated-polymer-nanoparticles-for-remote-control-of-gene-expression-in-living-cells
#4
Yunxia Wang, Shengliang Li, Pengbo Zhang, Haotian Bai, Liheng Feng, Fengting Lv, Libing Liu, Shu Wang
Remote control and noninvasive manipulation of cellular bioprocess has received intensive attention as a powerful technology to control cell functions. Here, a strategy is developed to remotely control intracellular gene expression with high spatial and temporal resolutions by using photothermal-responsive conjugated polymer nanoparticles (CPNs) as the transducer under near-infrared light irradiation. After being modified with positive charged peptide, the CPNs with superior photothermal conversion capacity could effectively coat on the surface of living cells and generate localized heat to trigger target gene expression...
January 12, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29323339/a-green-method-to-leach-vanadium-and-chromium-from-residue-using-naoh-h2o2
#5
Hao Peng, Zuohua Liu, Changyuan Tao
Hydrogen peroxide as an oxidant was applied in leaching of vanadium and chromium in concentrated NaOH solution. Under the optimal reaction conditions (the liquid to solid ratio of 4.0 ml/g, residue particle size of <200 mesh, the mass ratio of NaOH-to-residue of 1.0 g/g, the volume ratio of H2O2-to-residue of 1.2 ml/g, reaction temperature of 90 °C and reaction time of 120 min), the leaching efficiency of vanadium and chromium could reach up to 98.60% and 86.49%, respectively. Compared with the current liquid-phase oxidation technologies, the reaction temperature was 90-310 °C lower, and the NaOH concentration of the reaction medium is lower by more than 50 wt% (the mass ratio of NaOH-to-residue of 1...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29322019/to-identify-or-not-to-identify-parathyroid-glands-during-total-thyroidectomy
#6
REVIEW
Yuk Kwan Chang, Brian H H Lang
Hypoparathyroidism is one of the most common complications after total thyroidectomy and may impose a significant burden to both the patient and clinician. The extent of thyroid resection, surgical techniques, concomitant central neck dissection, parathyroid gland (PG) autotransplantation and inadvertent parathyroidectomy have long been some of the risk factors for postoperative hypoparathyroidism. Although routine identification of PGs has traditionally been advocated by surgeons, recent evidence has suggested that perhaps identifying fewer number of in situ PGs during surgery (i...
December 2017: Gland Surgery
https://www.readbyqxmd.com/read/29318813/red-fluorescence-of-dental-biofilm-as-an-indicator-for-assessing-the-efficacy-of-antimicrobials
#7
Eun-Song Lee, Elbert de Josselin de Jong, Hoi-In Jung, Baek-Il Kim
The study aimed to determine whether the red fluorescence (RF) of a dental microcosm biofilm as measured with quantitative light-induced fluorescence (QLF) technology is useful for assessing the efficacy of antimicrobials. Dental microcosm biofilms were formed on bovine enamel discs and grown under 0.3% sucrose challenge and treated with chlorhexidine (CHX) solutions at different concentrations (0.05%, 0.1%, and 0.5%) plus a negative control [sterile distilled water (DW)] twice daily for 7 days. The biofilms were photographed using a QLF-digital system to evaluate the RF by calculating the red/green ratio, and pH values of the medium were measured daily...
January 2018: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/29317716/a-quantum-biomimetic-electronic-nose-sensor
#8
Ashlesha Patil, Dipankar Saha, Swaroop Ganguly
We propose a technologically feasible one-dimensional double barrier resonant tunneling diode (RTD) as electronic nose, inspired by the vibration theory of biological olfaction. The working principle is phonon-assisted inelastic electron tunneling spectroscopy (IETS), modeled here using the Non-Equilibrium Green Function formalism for quantum transport. While standard IETS requires low-temperature operation to obviate the thermal broadening of spectroscopic peaks, we show that quantum confinement in the well of the RTD provides electron energy filtering in this case and could thereby allow room-temperature operation...
January 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29316728/tio%C3%A2-films-modified-with-au-nanoclusters-as-self-cleaning-surfaces-under-visible-light
#9
Ting-Wei Liao, Sammy W Verbruggen, Nathalie Claes, Anupam Yadav, Didier Grandjean, Sara Bals, Peter Lievens
In this study, we applied cluster beam deposition (CBD) as a new approach for fabricating efficient plasmon-based photocatalytic materials. Au nanoclusters (AuNCs) produced in the gas phase were deposited on TiO₂ P25-coated silicon wafers with coverage ranging from 2 to 8 atomic monolayer (ML) equivalents. Scanning Electron Microscopy (SEM) images of the AuNCs modified TiO₂ P25 films show that the surface is uniformly covered by the AuNCs that remain isolated at low coverage (2 ML, 4 ML) and aggregate at higher coverage (8 ML)...
January 8, 2018: Nanomaterials
https://www.readbyqxmd.com/read/29313555/correlation-of-values-for-indocyanine-green-angiography-in-the-arterographically-normal-lower-extremity
#10
Paul J Kim, Christopher E Attinger, Cameron M Akbari, Caitlin Ward
INTRODUCTION: Indocyanine green angiography (ICGA) is an assessment tool used to detect the degree of perfusion of tissue. This technology is being utilized in a variety of applications, including in the lower extremity. Principally, ICGA has been reported as a tool to determine pre-, intra-, or post-operative perfusion. The aim of this study is to determine objective values for ICGA in patients with arterographically normal lower extremities. MATERIALS AND METHODS: Prospectively, 20 patients were identified with no history of peripheral vascular disease who were scheduled to undergo distal subtraction angiography of the lower extremity...
December 22, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/29306921/building-a-high-quality-oncology-nursing-workforce-through-lifelong-learning-the-de-souza-model
#11
Mary Jane Esplen, Jiahui Wong, Esther Green, Joy Richards, Jane Li
AbstractCancer is one of the leading causes of death in the world. Along with increased new cases, cancer care has become increasingly complex due to advances in diagnostics and treatments, greater survival, and new models of palliative care. Nurses are a critical resource for cancer patients and their families. Their roles and responsibilities are expanding across the cancer care continuum, calling for specialized training and support. Formal education prepares nurses for entry level of practice, however, it does not provide the specialized competencies required for quality care of cancer patients...
January 5, 2018: International Journal of Nursing Education Scholarship
https://www.readbyqxmd.com/read/29302118/blood-and-blood-product-conservation-results-of-strategies-to-improve-clinical-outcomes-in-open-heart-surgery-patients-at-a-tertiary-hospital
#12
Junaid H Khan, Emily A Green, Jimmin Chang, Alexandria M Ayala, Marilyn S Barkin, Emily E Reinys, Jeffrey Stanton, Russell D Stanten
Blood product usage is a quality outcome for patients undergoing cardiac surgery. To address an increase in blood product usage since the discontinuation of aprotinin, blood conservation strategies were initiated at a tertiary hospital in Oakland, CA. Improving transfusion rates for open heart surgery patients requiring Cardiopulmonary bypass (CPB) involved multiple departments in coordination. Specific changes to conserve blood product usage included advanced CPB technology upgrades, and precise individualized heparin dose response titration assay for heparin and protamine management...
December 2017: Journal of Extra-corporeal Technology
https://www.readbyqxmd.com/read/29300678/simultaneous-extraction-and-enrichment-of-reactive-dye-using-green-emulsion-liquid-membrane-system
#13
Norasikin Othman, Raja Norimie Raja Sulaiman, Hilmi Abdul Rahman, Norul Fatiha Mohamad Noah, Norela Jusoh, Mariani Idroas
Currently, an extractive green palm oil based emulsion liquid membrane (ELM) has been used for simultaneous extraction and enrichment of Reactive Red 3BS from simulated synthetic dye wastewater. The ELM consists of two main phases which are organic liquid membrane and stripping solution. During the extraction process, the ELM was dispersed into the simulated synthetic dye wastewater containing the Reactive Red 3BS complexes. The organic liquid membrane contained Tridodecylamine (TDA), Sorbitan Monooleate (Span 80) and palm oil as a carrier, surfactant and diluent, respectively...
January 4, 2018: Environmental Technology
https://www.readbyqxmd.com/read/29300364/%C3%B0-c31-integrase-mediated-isolation-and-characterization-of-novel-safe-harbors-for-transgene-expression-in-the-pig-genome
#14
Yanzhen Bi, Zaidong Hua, Hongyan Ren, Liping Zhang, Hongwei Xiao, Ximei Liu, Wenjun Hua, Shuqi Mei, Adrian Molenaar, Götz Laible, Xinmin Zheng
Programmable nucleases have allowed the rapid development of gene editing and transgenics, but the technology still suffers from the lack of predefined genetic loci for reliable transgene expression and maintenance. To address this issue, we used ФC31 integrase to navigate the porcine genome and identify the pseudo attP sites suitable as safe harbors for sustained transgene expression. The combined ФC31 integrase mRNA and an enhanced green fluorescence protein (EGFP) reporter donor were microinjected into one-cell zygotes for transgene integration...
January 4, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29300085/energetically-autonomous-wearable-and-multifunctional-sensor
#15
Hsing-Hua Hsieh, Fang-Chi Hsu, Yang-Fang Chen
Self-powered tactile sensing is the upcoming technological orientation for developing compact, robust, and energy-saving devices in human-machine interfacing and electronic skin. Here, we report an intriguing type of sensing device composed of a Pt crack-based sensor in series with a polymer solar cell as a building block for energetically autonomous, wearable, and tactile sensor. This coplanar device enables human activity and physiological monitoring under indoor light illumination (2 mW/cm2) with acceptable and readible output signals...
January 4, 2018: ACS Sensors
https://www.readbyqxmd.com/read/29285485/a-novel-prokaryotic-green-fluorescent-protein-expression-system-for-testing-gene-editing-tools-activity-like-zinc-finger-nuclease
#16
Faezeh Sabzehei, Shirin Kouhpayeh, Mansoureh Shahbazi Dastjerdeh, Hossein Khanahmad, Rasoul Salehi, Shamsi Naderi, Razieh Taghizadeh, Parisa Rabiei, Zahra Hejazi, Laleh Shariati
Background: Gene editing technology has created a revolution in the field of genome editing. The three of the most famous tools in gene editing technology are zinc finger nucleases (ZFNs), transcription activator-like effector nucleases, clustered regularly interspaced short palindromic repeats (CRISPR), and CRISPR-associated systems. As their predictable nature, it is necessary to assess their efficiency. There are some methods for this purpose, but most of them are time labor and complicated...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/29283495/impact-of-sensor-controlled-variable-rate-fungicide-application-on-yield-senescence-and-disease-occurrence-in-winter-wheat-fields
#17
Maria Tackenberg, Christa Volkmar, Michael Schirrmann, Antje Giebel, Karl-Heinz Dammer
BACKGROUND: Field experiments related to target-oriented variable-rate fungicide spraying were performed in 2015 and 2016. The spray volume was adapted in real time to the local green coverage level of winter wheat (Triticum aestivum L.), which was detected by a camera sensor. RESULTS: Depending on the growth heterogeneity in the three strip trials in 2015, the fungicide savings in the sensor sprayed strip compared to the adjacent uniformly sprayed strip were 44 %, 45 % and 1 %...
December 28, 2017: Pest Management Science
https://www.readbyqxmd.com/read/29281904/laccase-grafted-membranes-for-advanced-water-filtration-systems-a-green-approach-to-water-purification-technology
#18
Jagdeep Singh, Vicky Saharan, Sanjay Kumar, Pooja Gulati, Rajeev Kumar Kapoor
PURPOSE: Conventional wastewater treatment technologies are not good enough to completely remove all endocrine disrupting compounds (EDCs) from the water. Membrane separation systems have emerged as an attractive alternative to conventional clarification processes for waste and drinking water. Coupling of a membrane separation process with an enzymatic reaction has opened up new avenues to further enhance the quality of water. This review article deliberates the feasibility of implementing enzymatic membrane reactors has been deliberated...
December 27, 2017: Critical Reviews in Biotechnology
https://www.readbyqxmd.com/read/29278978/statistical-optimization-of-arsenic-biosorption-by-microbial-enzyme-via-ca-alginate-beads
#19
Suchetana Banerjee, Anindita Banerjee, Priyabrata Sarkar
Bioremediation of arsenic using green technology via microbial enzymes has attracted scientists due to its simplicity and cost effectiveness. Statistical optimization of arsenate bioremediation was conducted by the enzyme arsenate reductase extracted from arsenic tolerant bacterium Pseudomonas alcaligenes. Response surface methodology based on Box-Behnken design matrix was performed to determine the optimal operational conditions of a multivariable system and their interactive effects on the bioremediation process...
December 26, 2017: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
https://www.readbyqxmd.com/read/29278733/enhancing-the-solubility-and-bioavailability-of-poorly-water-soluble-drugs-using-supercritical-antisolvent-sas-process
#20
Sharif Md Abuzara, Sang-Min Hyun, Jun-Hee Kim, Hee Jun Park, Min-Soo Kim, Jeong-Sook Park, Sung-Joo Hwang
Poor water solubility and poor bioavailability are problems with many pharmaceuticals. Increasing surface area by micronization is an effective strategy to overcome these problems, but conventional techniques often utilize solvents and harsh processing, which restricts their use. Newer, green technologies, such as supercritical fluid (SCF)-assisted particle formation, can produce solvent-free products under relatively mild conditions, offering many advantages over conventional methods. The antisolvent properties of the SCFs used for microparticle and nanoparticle formation have generated great interest in recent years, because the kinetics of the precipitation process and morphologies of the particles can be accurately controlled...
December 23, 2017: International Journal of Pharmaceutics
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