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https://www.readbyqxmd.com/read/28448474/innovative-green-and-novel-strategies-for-the-extraction-of-bioactive-added-value-compounds-from-citrus-wastes-a-review
#1
REVIEW
Predrag Putnik, Danijela Bursać Kovačević, Anet Režek Jambrak, Francisco J Barba, Giancarlo Cravotto, Arianna Binello, Jose Manuel Lorenzo, Avi Shpigelman
Citrus is a major processed crop that results in large quantities of wastes and by-products rich in various bioactive compounds such as pectins, water soluble and insoluble antioxidants and essential oils. While some of those wastes are currently valorised by various technologies (yet most are discarded or used for feed), effective, non-toxic and profitable extraction strategies could further significantly promote the valorisation and provide both increased profits and high quality bioactives. The present review will describe and summarize the latest works concerning novel and greener methods for valorisation of citrus by-products...
April 27, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28446946/neural-imaging-using-single-photon-avalanche-diodes
#2
Mohammad Azim Karami, Misagh Ansarian
INTRODUCTION: This paper analyses the ability of single-photon avalanche diodes (SPADs) for neural imaging. The current trend in the production of SPADs moves toward the minimum dark count rate (DCR) and maximum photon detection probability (PDP). Moreover, the jitter response which is the main measurement characteristic for the timing uncertainty is progressing. METHODS: The neural imaging process using SPADs can be performed by means of florescence lifetime imaging (FLIM), time correlated single-photon counting (TCSPC), positron emission tomography (PET), and single-photon emission computed tomography (SPECT)...
January 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28441036/application-of-arthrospira-spirulina-platensis-biomass-for-silver-removal-from-aqueous-solutions
#3
Inga Zinicovscaia, Liliana Cepoi, Tatiana Chiriac, Tatiana Mitina, Dmitrii Grozdov, Nikita Yushin, Otilia Culicov
The cyanobacterium Arthrospira (Spirulina) platensis was used to study the process of silver biosorption. Effects of various parameters such as contact time, dosage of biosorbent, initial pH, temperature, and initial concentration of Ag(I) were investigated for a batch adsorption system. The optimal biosorption conditions were determined as pH 5.0, biosorbent dosage of 0.4 g, and initial silver concentration of 30 mg/L. Equilibrium adsorption data were analyzed by the Langmuir and Freundlich models - however, the Freundlich model provided a better fit with the experimental data...
April 25, 2017: International Journal of Phytoremediation
https://www.readbyqxmd.com/read/28440211/a-cluster-randomised-trial-cost-effectiveness-analysis-and-psychosocial-evaluation-of-insulin-pump-therapy-compared-with-multiple-injections-during-flexible-intensive-insulin-therapy-for-type-1-diabetes-the-repose-trial
#4
Simon Heller, David White, Ellen Lee, Julia Lawton, Daniel Pollard, Norman Waugh, Stephanie Amiel, Katharine Barnard, Anita Beckwith, Alan Brennan, Michael Campbell, Cindy Cooper, Munyaradzi Dimairo, Simon Dixon, Jackie Elliott, Mark Evans, Fiona Green, Gemma Hackney, Peter Hammond, Nina Hallowell, Alan Jaap, Brian Kennon, Jackie Kirkham, Robert Lindsay, Peter Mansell, Diana Papaioannou, David Rankin, Pamela Royle, W Henry Smithson, Carolin Taylor
BACKGROUND: Insulin is generally administered to people with type 1 diabetes mellitus (T1DM) using multiple daily injections (MDIs), but can also be delivered using infusion pumps. In the UK, pumps are recommended for patients with the greatest need and adult use is less than in comparable countries. Previous trials have been small, of short duration and have failed to control for training in insulin adjustment. OBJECTIVE: To assess the clinical effectiveness and cost-effectiveness of pump therapy compared with MDI for adults with T1DM, with both groups receiving equivalent structured training in flexible insulin therapy...
April 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28438012/smartphone-based-dual-modality-imaging-system-for-quantitative-detection-of-color-or-fluorescent-lateral-flow-immunochromatographic-strips
#5
Yafei Hou, Kan Wang, Kun Xiao, Weijian Qin, Wenting Lu, Wei Tao, Daxiang Cui
Nowadays, lateral flow immunochromatographic assays are increasingly popular as a diagnostic tool for point-of-care (POC) test based on their simplicity, specificity, and sensitivity. Hence, quantitative detection and pluralistic popular application are urgently needed in medical examination. In this study, a smartphone-based dual-modality imaging system was developed for quantitative detection of color or fluorescent lateral flow test strips, which can be operated anywhere at any time. In this system, the white and ultra-violet (UV) light of optical device was designed, which was tunable with different strips, and the Sobel operator algorithm was used in the software, which could enhance the identification ability to recognize the test area from the background boundary information...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28436511/self-template-synthesis-of-cds-nisx-heterostructured-nanohybrids-for-efficient-photocatalytic-hydrogen-evolution
#6
You Xu, Wenguang Tu, Shengming Yin, Markus Kraft, Qichun Zhang, Rong Xu
Photocatalytic hydrogen (H2) evolution from water splitting is attracting enormous interest due to the possibility of converting solar energy into green chemical energy. The construction of highly efficient and stable photocatalysts is of importance and necessary for the development of photocatalytic water splitting technology. In this study, we have developed a self-template synthetic strategy for the preparation of heterostructured nanohybrids composed of ultrasmall CdS and NiSx nanoparticles by using Cd(ii)-Ni(ii)-(4,4'-bipyridine) coordination polymers as the precursor and template...
April 24, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28435109/visible-light-inactivation-of-e-%C3%A2-coli-cytotoxicity-and-ros-determination-of-biochemically-capped-gold-nanoparticles
#7
Faheem Ullah Khan, Yongmei Chen, Naeem Ullah Khan, Aftab Ahmad, Kamran Tahir, Zia UlHaq Khan, Arif Ullah Khan, Shifa Ullah Khan, Muslim Raza, Pingyu Wan
The formation of metal nanoparticles is one of the most vast and intensifying research areas in favor of prospective applications for the advancement of new technologies. It is a well-founded, significant feature of green chemistry that making marvelous interconnection between nano-biotechnology and microbial biotechnology. In the present research, the aqueous extract of medicinally important plant Coptis Chinensis (in Chinese called "gold thread") was applied for the synthesis of gold nanoparticles (Au-NPs)...
April 20, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28433367/abnormal-implantation-after-fresh-and-frozen-in%C3%A2-vitro-fertilization-cycles
#8
Erica T Wang, Anupama S Q Kathiresan, Catherine Bresee, Naomi Greene, Carolyn Alexander, Margareta D Pisarska
OBJECTIVE: To determine whether fresh embryo transfers are at a higher risk of abnormal implantation compared with frozen embryo transfers while accounting for the embryo stage at transfer. DESIGN: Retrospective cohort study. SETTING: Not applicable. PATIENT(S): We used data from the Society for Assisted Reproductive Technologies to identify all fresh and frozen autologous IVF cycles from 2004-2013 resulting in a positive pregnancy test...
April 19, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28433060/enhanced-photoresponsive-polyethyleneimine-citric-acid-co-carbonized-dots-for-facile-and-selective-sensing-and-intracellular-imaging-of-cobalt-ions-at-physiologic-ph
#9
Wen-Sheng Zou, Qing-Chun Zhao, Jun Zhang, Xiao-Ming Chen, Xiu-Fang Wang, Lin Zhao, Shao-Hua Chen, Ya-Qin Wang
Whether as an important biological element or as a radioactive source/medicine, the monitoring of trace levels of cobalt ions (Co) has become a non-negligible factor for human health and green environment. Current technologies for the detection of Co are cost-expensive and time-consuming, and require cumbersome sample pretreatment process. Herein a novel sensing platform has been developed for Co detection based on the quenching of the enhanced fluorescence signal of polyamine functionalized C-dots. Amine groups at the surface of the C-dots can capture Zn(2+)/Cd(2+) to form coordination compound, which can inhibit the photoinduced electron transfer pathways of C-dots and then induce the fluorescence enhancement of the C-dots by ∼80% margin...
June 1, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28429630/new-and-emerging-risks-associated-with-green-workplaces
#10
Dorota Elżbieta Wandzich, Grażyna Anna Płaza
Work environments are continuously changing with the introduction of new technologies, substances and work processes, changes in the structure of the workforce and labor market, and new forms of employment and work organization. New work situations bring both risks and challenges for workers and employers, which, in turn, may require political, administrative, technical, and regulatory approaches to ensure worker safety and health. This article is based on a European Agency for Safety and Health at Work (EU-OSHA) report, Green Jobs and Occupational Safety and Health, that detailed new and emerging risks to occupational safety and health associated with new technologies in green jobs...
April 1, 2017: Workplace Health & Safety
https://www.readbyqxmd.com/read/28428282/whither-radioimmunotherapy-to-be-or-not-to-be
#11
Damian J Green, Oliver W Press
Therapy of cancer with radiolabeled monoclonal antibodies has produced impressive results in preclinical experiments and in clinical trials conducted in radiosensitive malignancies, particularly B-cell lymphomas. Two "first-generation," directly radiolabeled anti-CD20 antibodies, (131)iodine-tositumomab and (90)yttrium-ibritumomab tiuxetan, were FDA-approved more than a decade ago but have been little utilized because of a variety of medical, financial, and logistic obstacles. Newer technologies employing multistep "pretargeting" methods, particularly those utilizing bispecific antibodies, have greatly enhanced the therapeutic efficacy of radioimmunotherapy and diminished its toxicities...
April 20, 2017: Cancer Research
https://www.readbyqxmd.com/read/28426217/phosphorus-depletion-as-a-green-alternative-to-biocides-for-controlling-biodegradation-of-metalworking-fluids
#12
Yaldah Azimi, Ian P Thompson
Metalworking fluids (MWFs) are used as lubricants and coolants in the manufacturing operations. Their biodeterioration, whilst in-operation, is a widespread problem leading to poor performance and worker health issues. Adding biocides, though effective in reducing microbial growth, leads to the production of more recalcitrant wastewaters that are difficult to dispose or recycle on-site. Increasing environmental concerns have led to robust legislation for reducing/eliminating the use of toxic biocides in MWFs, stimulating a growing interest in the development/application of alternative biological preservation strategies...
April 20, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28422222/electron-transfer-in-silicon-bridged-adjacent-chromophores-the-source-for-blue-green-emission
#13
Malgorzata Bayda, Gonzalo Angulo, Gordon L Hug, Monika Ludwiczak, Jerzy Karolczak, Jacek Koput, Jacek Dobkowski, Bronislaw Marciniak
Si-Bridged chromophores have been proposed as sources for blue-green emission in several technological applications. The origin of this dual emission is to be found in an internal charge transfer reaction. The current work is an attempt to describe the details of these processes in these kinds of substances, and to design a molecular architecture to improve their performance. Nuclear motions essential for intramolecular charge transfer (ICT) can involve processes from twisted internal moieties to dielectric relaxation of the solvent...
April 19, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28417174/multidimensional-single-cell-analysis-based-on-fluorescence-microscopy-and-automated-image-analysis
#14
Michael Sandmann, Martin Lippold, Franziska Saalfrank, Chimezie Progress Odika, Sascha Rohn
A single-cell analytical technology was developed for evaluating fast-growing cultures of green algae. The main part of the single-cell analysis is an epifluorescence microscopy-based cytometric approach combined with an automated image analysis algorithm and a single-threshold discrimination procedure. The reliability of the technique in terms of object recognition, evaluating particle size, and determining chlorophyll was successfully proven via reference analyses. The microscopy technique was used to determine the size of single cells, the amount of chlorophyll, and the density of chlorophyll in a model algal culture (Acutodesmus o...
April 17, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28414190/engineered-polymeric-microspheres-obtained-by-multi-step-method-as-potential-systems-for-transarterial-embolization-and-intraoperative-imaging-of-hcc-preliminary-evaluation
#15
Elena Piera Porcu, Andrea Salis, Giovanna Rassu, Marcello Maestri, Jacopo Galafassi, Giovanna Bruni, Paolo Giunchedi, Elisabetta Gavini
The aim of this study was the development of novel fluorescent microspheres as embolic agent for transarterial embolization (TAE) of advanced stages of hepatocellular carcinoma (HCC). TAE is a minimally invasive procedure that induces tumour regression blocking the blood flow by injection of microparticles. The microspheres currently used in clinical application cannot be visualized in vivo. Surgeon could exploit the intraoperative detection of embolic agents during resection of the malignant mass. Biocompatible indocyanine green (ICG)-loaded microspheres (CAB-CS-ICG) were prepared using a multi-step method...
April 13, 2017: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/28413446/artificial-mirna-inhibition-of-phosphoenolpyruvate-carboxylase-increases-fatty-acid-production-in-a-green-microalga-chlamydomonas-reinhardtii
#16
Chaogang Wang, Xi Chen, Hui Li, Jiangxin Wang, Zhangli Hu
BACKGROUND: Nutrient limitation, such as nitrogen depletion, is the most widely used method for improving microalgae fatty acid production; however, these harsh conditions also inhibit algal growth significantly and even kill cells at all. To avoid these problems, we used artificial microRNA (amiRNA) technology as a useful tool to manipulate metabolic pathways to increase fatty acid contents effectively in the green microalga Chlamydomonas reinhardtii. We down-regulated the expression of phosphoenolpyruvate carboxylase (PEPC), which catalyzes the formation of oxaloacetate from phosphoenolpyruvate and regulates carbon flux...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28409504/comparative-study-of-the-transfection-efficiency-of-commonly-used-viral-vectors-in-rhesus-monkey-macaca-mulatta-brains
#17
Shi-Hao Wu, Zhi-Xing Liao, Joshua D Rizak, Na Zheng, Lin-Heng Zhang, Hen Tang, Xiao-Bin He, Yang Wu, Xia-Ping He, Mei-Feng Yang, Zheng-Hui Li, Dong-Dong Qin, Xin-Tian Hu
Viral vector transfection systems are among the simplest of biological agents with the ability to transfer genes into the central nervous system. In brain research, a series of powerful and novel gene editing technologies are based on these systems. Although many viral vectors are used in rodents, their full application has been limited in non-human primates. To identify viral vectors that can stably and effectively express exogenous genes within non-human primates, eleven commonly used recombinant adeno-associated viral and lentiviral vectors, each carrying a gene to express green or red fluorescence, were injected into the parietal cortex of four rhesus monkeys...
March 18, 2017: Zoological Research
https://www.readbyqxmd.com/read/28408967/the-temperature-dependence-of-multiphonon-relaxation-of-rare-earth-ions-in-solid-state-hosts
#18
Dechao Yu, John Ballato, Richard E Riman
Rare-earth ions are used in a wide range of emissive devices - ranging from lasers to displays - where high optical efficiency and narrow-linewidth are important. While their radiative properties are important, nonradiative properties are also critical since they can reduce optical efficiency and generate heat. In this paper, theories for multiphonon relaxation rate are reviewed for rare-earth excited states in solid-state dielectric hosts. A range of various approaches are used to simplify the mathematical form of the rate equations...
May 12, 2016: Journal of Physical Chemistry. C, Nanomaterials and Interfaces
https://www.readbyqxmd.com/read/28408212/application-of-molecular-imaging-technology-in-evaluating-the-inhibiting-effect-of-apigenin-in%C3%A2-vivo-on-subcutaneous-hepatocellular-carcinoma
#19
Gang Li, Chong-Wei Chi, Xian-Fang Shao, Chi-Hua Fang
The aim of this study was to evaluate the inhibiting effect of apigenin on liver cancer in vivo based on the optical molecular imaging method. Subcutaneous liver tumor models were established using respective 1 × 10(6) firefly luciferase (fLuc) and green fluorescent protein (GFP) labeled human hepatocellular carcinoma cells (HepG2-fLuc and HepG2-GFP cells) in 20 BALB/c nude mice which were randomly divided into two groups, 10 in each group. After the tumor cells were implanted 15 days, apigenin was administered through intraperitoneal injection in group B, the other ten mice as control group A...
May 20, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28407963/an-improved-method-for-extraction-of-nutraceutically-important-polyphenolics-from-berberis-jaeschkeana-c-k-schneid-fruits
#20
Tarun Belwal, Lalit Giri, Indra D Bhatt, Ranbeer S Rawal, Veena Pande
Berberis jaeschkeana fruits, source of nutraceutically important polyphenolics were investigated. A total of 32 experimental run were conducted under Plackett-Burman and central composite design. Microwave power, methanol and HCl concentration significantly (p<0.05) affect extraction of polyphenols under linear, quadratic and interactive effect. The model showed good fitness with significant (p<0.05) model F-value and a non-significant lack of fit. Under optimum microwave assisted extraction (MAE) condition the total phenolics, flavonoids, tannins and antioxidant activity were in closed context with predicted values...
September 1, 2017: Food Chemistry
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