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Impulse-Control Disorders

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https://www.readbyqxmd.com/read/29781205/double-trouble-weekend-sleep-changes-are-associated-with-increased-impulsivity-among-adolescents-with-bipolar-i-disorder
#1
Anda Gershon, Sheri L Johnson, Leigh Thomas, Manpreet K Singh
OBJECTIVES: Both sleep disruption and impulsivity are important predictors of the course of bipolar disorder (BD). Although sleep disruption has been shown to intensify impulsivity, little research has considered how these two important domains interact within BD. Adolescence is a critical period for the onset of BD, and is often associated with increases in impulsivity and substantial changes in sleep. We tested the hypothesis that disruptions in sleep would increase impulsivity among adolescents, and that this effect would be more pronounced among those with BD...
May 20, 2018: Bipolar Disorders
https://www.readbyqxmd.com/read/29780342/long-term-efficacy-of-psychosocial-treatments-for-adults-with-attention-deficit-hyperactivity-disorder-a-meta-analytic-review
#2
Carlos López-Pinar, Sonia Martínez-Sanchís, Enrique Carbonell-Vayá, Javier Fenollar-Cortés, Julio Sánchez-Meca
Background: Recent evidence suggests that psychosocial treatments, particularly cognitive-behavioral therapy (CBT), are effective interventions for adult attention deficit hyperactivity disorder (ADHD). The objective of this review was to determine the long-term efficacy of psychosocial interventions in improving clinically relevant variables, including ADHD core symptoms, clinical global impression (CGI), and global functioning. Methods: In total, nine randomized controlled trials and three uncontrolled single-group pretest-posttest studies were included...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29778625/the-mediating-role-of-phosphodiesterase-type-4-in-the-dopaminergic-modulation-of-motor-impulsivity
#3
P R A Heckman, A Blokland, N P Van Goethem, B T J Van Hagen, J Prickaerts
The current study investigated the mediating role of phosphodiesterase type 4 (PDE4) regulated cAMP in the dopaminergic modulation of premature responding (action restraint) in rats. Response inhibition, which includes action restraint, finds its neurobiological origin in cortico-striatal-thalamic circuitry and can be modulated by dopamine. Intracellularly, the effect of dopamine is largely mediated through the cAMP/PKA signaling cascade. Areas in the prefrontal cortex are very sensitive to their neurochemical environment, including catecholamine levels...
May 17, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29772488/minnesota-impulse-disorders-interview-midi-validation-of-a-structured-diagnostic-clinical-interview-for-impulse-control-disorders-in-an-enriched-community-sample
#4
Samuel R Chamberlain, Jon E Grant
BACKGROUND: Disorders of impulsivity are common, functionally impairing, and highly relevant across different clinical and research settings. Few structured clinical interviews for the identification and diagnosis of impulse control disorders exist, and none have been validated in a community sample in terms of psychometric properties. METHODS: The Minnesota Impulse control disorders Interview (MIDI v2.0) was administered to an enriched sample of 293 non-treatment seeking adults aged 18-35 years, recruited using media advertisements in two large US cities...
May 8, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29771172/measuring-impulsivity-in-children-adaptation-and-validation-of-a-short-version-of-the-upps-p-impulsive-behaviors-scale-in-children-and-investigation-of-its-links-with-adhd
#5
Marie Geurten, Corinne Catale, Philippe Gay, Sandrine Deplus, Joël Billieux
OBJECTIVE: Impulsivity is a multifaceted construct known to play a crucial role in the development and maintenance of a wide range of problematic behaviors and psychological disorders in children. METHOD: In this study, we adapted the short French adult version of the UPPS-P (urgency-premeditation-perseverance-sensation seeking-positive urgency) Impulsive Behaviors Scale for use with children (short UPPS-P-C) and tested its psychometric properties. RESULTS: Confirmatory factor analyses conducted on a sample of 425 children (aged 8-14 years) supported the five-factor structure of the scale...
May 1, 2018: Journal of Attention Disorders
https://www.readbyqxmd.com/read/29756232/differences-in-emotion-regulation-difficulties-among-adults-and-adolescents-across-eating-disorder-diagnoses
#6
Leslie K Anderson, Kimberly Claudat, Anne Cusack, Tiffany A Brown, Julie Trim, Roxanne Rockwell, Tiffany Nakamura, Lauren Gomez, Walter H Kaye
OBJECTIVE: Although much empirical attention has been devoted to emotion regulation (ER) in individuals with eating disorders, little is known about ER across a wide age range and among different ED subtypes. The current study sought to examine ER in a sample of eating disorder patients. METHOD: A total of 364 adults and adolescents with anorexia nervosa restricting subtype (AN-R), anorexia nervosa binge/purge subtype (AN-BP), or bulimia nervosa (BN) were assessed with the Difficulties in Emotion Regulation Scale (DERS)...
May 13, 2018: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/29755401/impulsivity-in-parkinson-s-disease-is-associated-with-alterations-in-affective-and-sensorimotor-striatal-networks
#7
Marit F L Ruitenberg, Tina Wu, Bruno B Averbeck, Kelvin L Chou, Vincent Koppelmans, Rachael D Seidler
A subset of patients with Parkinson's disease (PD) experiences problems with impulse control, characterized by a loss of voluntary control over impulses, drives, or temptations regarding excessive hedonic behavior. The present study aimed to better understand the neural basis of such impulse control disorders (ICDs) in PD. We collected resting-state functional connectivity and structural MRI data from 21 PD patients with ICDs and 30 patients without such disorders. To assess impulsivity, all patients completed the Barratt Impulsiveness Scale and performed an information-gathering task...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29751598/informed-consent-decision-making-in-deep-brain-stimulation
#8
REVIEW
Gabriele Mandarelli, Germana Moretti, Massimo Pasquini, Giuseppe Nicolò, Stefano Ferracuti
Deep brain stimulation (DBS) has proved useful for several movement disorders (Parkinson’s disease, essential tremor, dystonia), in which first and/or second line pharmacological treatments were inefficacious. Initial evidence of DBS efficacy exists for refractory obsessive-compulsive disorder, treatment-resistant major depressive disorder, and impulse control disorders. Ethical concerns have been raised about the use of an invasive surgical approach involving the central nervous system in patients with possible impairment in cognitive functioning and decision-making capacity...
May 11, 2018: Brain Sciences
https://www.readbyqxmd.com/read/29749462/immunotherapy-by-targeting-of-vgkc-complex-for-seizure-control-and-prevention-of-cognitive-impairment-in-a-mouse-model-of-epilepsy
#9
Zhiliang Fan, Xiaojuan Feng, Zhigang Fan, Xingyuan Zhu, Shaohua Yin
Epilepsy is a type of refractory neurologic disorder mental disease, which is associated with cognitive impairments and memory dysfunction. However, the potential mechanisms of epilepsy are not well understood. Previous evidence has identified the voltage gated potassium channel complex (VGKC) as a target in various cohorts of patients with epilepsy. In the present study, the efficacy of an antibody against VGKC (anti‑VGKC) for the treatment of epilepsy in mice was investigated. A mouse model of lithium‑pilocarpine temporal lobe epilepsy was established and anti‑VGKC treatment was administered for 30 days...
May 9, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29748850/from-aggression-to-autism-new-perspectives-on-the-behavioral-sequelae-of-monoamine-oxidase-deficiency
#10
REVIEW
Marco Bortolato, Gabriele Floris, Jean C Shih
The two monoamine oxidase (MAO) enzymes, A and B, catalyze the metabolism of monoamine neurotransmitters, such as serotonin, norepinephrine, and dopamine. The phenotypic outcomes of MAO congenital deficiency have been studied in humans and animal models, to explore the role of these enzymes in behavioral regulation. The clinical condition caused by MAOA deficiency, Brunner syndrome, was first described as a disorder characterized by overt antisocial and aggressive conduct. Building on this discovery, subsequent studies were focused on the characterization of the role of MAOA in the neurobiology of antisocial conduct...
May 10, 2018: Journal of Neural Transmission
https://www.readbyqxmd.com/read/29747900/-cognitive-impairment
#11
Nicolas Cabé, Alice Laniepce, Céline Boudehent, Anne-Lise Pitel, François Vabret
Alcohol use disorder is a brain disease that can be modeled by an imbalance between three cerebral and cognitive systems. The reflective system, underpinned by the frontal cortex and corresponding to the executive functions, would be involved in the control of alcohol consumption. The impulsive system, underpinned by the amygdala-striatal complex, would favor automatic and impulsive drinking behaviors. A regulatory system, driven by insula and involved in the integration of proprioceptive perceptions in situations of deprivation or stress, would aggravate the imbalance between the two first systems...
May 7, 2018: La Presse Médicale
https://www.readbyqxmd.com/read/29747614/there-is-more-to-mental-illness-than-negative-affect-comprehensive-temperament-profiles-in-depression-and-generalized-anxiety
#12
Irina Trofimova, William Sulis
BACKGROUND: Temperament and mental illness are thought to represent varying degrees along the same continuum of neurotransmitter imbalances. A taxonomy of temperament could provide the basis for a new taxonomy of mental illness. Most popular models of temperament, being based heavily on emotionality traits, show very poor ability to discriminate between mental disorders. The main goal of this study was to examine whether a temperament model based on modern neurophysiology and possessing an extensive set of non-emotionality traits provides better discrimination between Major Depression (MD), Generalized Anxiety (GAD) and Comorbid MD and GAD, in comparison to emotionality-based temperament models...
May 10, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29740015/effects-of-5-aminolevulinic-acid-supplementation-on-home-based-walking-training-achievement-in-middle-aged-depressive-women-randomized-double-blind-crossover-pilot-study
#13
Hiroshi Suzuki, Shizue Masuki, Akiyo Morikawa, Yu Ogawa, Yoshi-Ichiro Kamijo, Kiwamu Takahashi, Motowo Nakajima, Hiroshi Nose
Depressive patients often experience difficulty in performing exercise due to physical and psychological barriers. We examined the effects of 5-aminolevulinic acid (ALA) with sodium ferrous citrate (SFC) supplementation during home-based walking training in middle-aged depressive women. Nine outpatients [53 ± 8 (SD) yr] with major depressive disorder participated in the pilot study with randomized, placebo-controlled, double-blind crossover design. They underwent two trials for 7 days, each performing interval walking training (IWT) with ALA + SFC (ALA + SFC) or placebo supplement intake (PLC) intermittently with >a 10-day washout period...
May 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29739286/sixfold-post-fracture-mortality-in-16-to-30-year-old-patients-suicides-homicides-and-intoxications-among-leading-causes-of-death
#14
A Somersalo, J Paloneva, E Lönnroos, M Heinänen, H Koponen, I Kiviranta
BACKGROUND AND AIMS: The death of any young individual is associated with the loss of many potentially fulfilling years of life. It has been suggested that the relative mortality of fracture patients may be higher in younger age groups than in older cohorts. We determined the mortality and causes of death in a cohort of 16- to 30-year-old patients that had been hospitalized for fractures. MATERIAL AND METHODS: We collected data using criteria based on the diagnosis code (International Statistical Classification of Diseases and Related Health Problems, 10th Revision), surgical procedure code (Nordic Medico-Statistical Committee), and seven additional characteristics of patients admitted to the trauma ward at the Central Finland Hospital between 2002 and 2008...
May 1, 2018: Scandinavian Journal of Surgery: SJS
https://www.readbyqxmd.com/read/29731439/inhibition-of-diet-restriction-induced-behavioral-deficits-by-tryptophan-administration-in-rats
#15
Darakhshan M Saleem, Shafaque Mehboob, Moona Mehboob Khan, Noreen Samad, Afshan Zafar, Darakhshan J Haleem
Diet has a great impact on brain health and function. It plays an important role to improve and control a number of psychiatric disorders such as depression, anxiety, hyperactivity and behavioral impulsivity. Anorexia Nervosa (AN) is one of the psychiatric disorder which is associated with diet. In AN, patients show extreme dieting, weight loss, hyperactivity, depression/anxiety, self-control and behavioral impulsivity. Previous studies showed that during diet restriction, tryptophan decreases serotonin (5-hydroxytryptamine; 5-HT) metabolism in the brain due to its less availability and contributes psychiatric problems associated with AN...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29730872/neuropeptide-y-levels-in-children-and-adolescents-with-attention-deficit-hyperactivity-disorder
#16
Özlem Hekim Bozkurt, Esra Güney, Zeynep Göker, Gülser Şenses Dinç, Murat Alışık, Özcan Erel, Esra Çöp, Özden Şükran Üneri
OBJECTIVE: Attention-deficit/hyperactivity disorder (ADHD) is one of the most common psychiatric disorders in adolescence, however, the etiology has not been described. Neuropeptide Y (NPY) is one potential factor that may be involved in the etiology of ADHD. The goal of this study was to evaluate NPY levels in children with ADHD and compare the findings to healthy controls. METHODS: Forty-eight ADHD patients and 40 healthy controls were included in this study. The age range of ADHD patients was 6 to 16 years...
2018: Türk Psikiyatri Dergisi, Turkish Journal of Psychiatry
https://www.readbyqxmd.com/read/29730510/early-life-stress-resilience-and-emotional-dysregulation-in-major-depressive-disorder-with-comorbid-borderline-personality-disorder
#17
Min-Kyeong Kim, Jong-Sun Kim, Hae-In Park, Sun-Woo Choi, Wook-Jin Oh, Jeong-Ho Seok
BACKGROUND: Borderline personality disorder (BPD) show different course and treatment compared to major depressive disorder (MDD). Early life stress may increase BPD onset; however, resilience may play a protective role against the development of psychopathology. The goal of this study was to compare the early life stress, resilience, and the clinical characteristics of emotional dysregulation in patients with MDD with and without comorbid BPD. METHODS: Thirty patients with both BPD and MDD, 25 patients with MDD alone, and 25 age- and sex- matched healthy controls, participated in this study...
April 27, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29723720/serum-uric-acid-levels-in-first-episode-mania-effect-on-clinical-presentation-and-treatment-response-data-from-a-case-control-study
#18
Seshadri Sekhar Chatterjee, Sutanuka Ghosal, Sayantanava Mitra, Nitu Mallik, Malay Kumar Ghosal
Bipolar disorder (BD) patients have increased serum Uric Acid (UA) levels as compared to their healthy counterparts. They also demonstrate higher impulsivity - while symptomatic, as well as when in remission. Impulsivity adds a risk of self-harming behavior to BD, and studies show that it increases with UA levels. Given this complex relationship, the current project aimed at comparing UA levels in first-episode mania patients with matched controls, and analyzes its relationship with impulsivity, symptom severity and disease prognosis...
April 26, 2018: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29718062/iowa-gambling-task-performance-in-parkinson-disease-patients-with-impulse-control-disorders
#19
Julia W Biars, Nicole L Johnson, Michelle Nespeca, Robyn M Busch, Cynthia S Kubu, Darlene P Floden
Objective: A subgroup of patients with Parkinson disease (PD) develops impulse control disorders (ICD) associated with their dopamine replacement therapy. Patients and their families may be reluctant to report ICD symptoms or unaware these symptoms are related to PD medication, which can make detecting an ICD difficult for clinicians. Ideally, a behavioral measure that is sensitive to ICD could be employed to ensure that patients with these behaviors are identified and treated. The Iowa Gambling Task (IGT), a standardized decision-making task, has proven sensitive in other populations with impulse control problems...
April 27, 2018: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/29717794/are-treatment-results-for-eating-disorders-affected-by-adhd-symptoms-a-one-year-follow-up-of-adult-females
#20
Nils Erik Svedlund, Claes Norring, Ylva Ginsberg, Yvonne von Hausswolff-Juhlin
OBJECTIVE: To explore the influence of self-reported Attention Deficit Hyperactivity Disorder (ADHD) symptoms on recovery rate at 1-year follow-up in an unselected group of patients in a specialized eating disorder (ED) clinic. METHODS: Four hundred forty-three adult females with an ED were assessed with the ADHD Self-Report Scale for Adults (ASRS-screener), and for demographic variables and ED symptoms. Recovery was registered at 1-year follow-up. RESULTS: A high degree of ADHD symptoms at baseline was predictive for nonrecovery of ED at 1-year follow-up in patients with loss of control over eating, bingeing, or purging...
May 2, 2018: European Eating Disorders Review: the Journal of the Eating Disorders Association
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