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carcinoma of the rectum

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https://www.readbyqxmd.com/read/28194526/long-term-outcomes-after-treatment-for-t1-colorectal-carcinoma-a-multicenter-retrospective-cohort-study-of-hiroshima-gi-endoscopy-research-group
#1
Yuzuru Tamaru, Shiro Oka, Shinji Tanaka, Shinji Nagata, Yuko Hiraga, Toshio Kuwai, Akira Furudoi, Tadamasa Tamura, Masaki Kunihiro, Hideharu Okanobu, Koichi Nakadoi, Hiroyuki Kanao, Makoto Higashiyama, Koji Arihiro, Kazuya Kuraoka, Fumio Shimamoto, Kazuaki Chayama
BACKGROUND: We aimed to clarify the long-term outcomes of patients with T1 colorectal carcinoma (CRC) after endoscopic resection (ER) and surgical resection. METHODS: We examined T1 CRC patients treated during 1992-2008 and who had ≥5 years of follow-up. Patients who did not meet the curative criteria after ER according to the Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines were defined as "non-endoscopically curable" and classified into three groups: ER alone (Group A: 121 patients), additional surgery after ER (Group B: 238 patients), and surgical resection alone (Group C: 342 patients)...
February 13, 2017: Journal of Gastroenterology
https://www.readbyqxmd.com/read/28157254/using-our-own-developed-stent-in-the-palliative-treatment-of-obstruction-in-the-left-half-of-the-colon-due-to-ovarian-cancer
#2
Tomasz Miłek, Konrad Pasek, Piotr Ciostek, Habib Alkalaya, Agnieszka Timorek, Włodzimierz Sawicki, Krzysztof Cendrowski
OBJECTIVES: An assessment of implantation efficacy and safety of self-developed self-expanding stent in patients with an ovarian cancer induced by intestinal obstruction. MATERIAL AND METHODS: The study of the stenting efficacy and safety was realized prospectively. The group consisted of 13 patients with left half colon obstruction due to an inoperable metastatic ovarian carcinoma. All the patients had a histopathologically diagnosed ovarian carcinoma and were treated in the past both surgically and systemically...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28144126/transanal-endoscopic-operation-for-benign-rectal-lesions-and-t1-carcinoma
#3
Mathieu D'Hondt, Emi Yoshihara, Lieven Dedrye, Koen Vindevoghel, Frederiek Nuytens, Hans Pottel
BACKGROUND AND OBJECTIVES: Transanal endoscopic operation (TEO) is a minimally invasive technique used for local excision of benign and selected malignant rectal lesions. The purpose of this study was to investigate the feasibility, safety, and oncological outcomes of the procedure and to report the experience in 3 centers. METHODS: Retrospective review of a prospectively collected database was performed of all patients with benign lesions or ≤cT1N0 rectal cancer who underwent TEO with curative intent at 3 Belgian centers (2012 through 2014)...
January 2017: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://www.readbyqxmd.com/read/28133240/-a-case-of-primary-peritoneal-cancer-successfully-treated-with-debulking-surgery-and-postoperative-chemotherapy
#4
Koki Maeda, Masami Tabata, Taiki Moriyama, Tatsuya Sakamoto, Yu Fujimura, Ichiro Ohsawa, Kenji Kato, Makoto Iwata, Takayuki Sanda
A 52-year-old woman with abdominal pain and a feeling of incomplete evacuation visited a local clinic. Enlargement of the right ovary was detected, and the patient was referred to the gynecological department of our hospital. CT and MRI revealed a round-shaped mass, 8 cm in diameter, with cystic and solid components in the Douglas pouch. The patient underwent a laparotomy under the diagnosis of ovarian cancer. Intraoperatively, both the ovaries appeared normal and the tumor strongly adhered to the rectum and uterus...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133091/-two-cases-pancreatic-carcinoma-detected-incidentally-during-treatment-of-acute-abdomen-from-other-causes
#5
Shigeru Fujisaki, Motoi Takashina, Ryouichi Tomita, Kenichi Sakurai, Tadatoshi Takayama
We report 2 cases of pancreatic cancer discovered incidentally in the wake of acute abdomen from other causes. Case 1 is a 67-year-old man who was referred to our hospital in October 2010 for the treatment of an incarcerated right inguinal hernia. The hernia was manually reduced, and mesh plug hernioplasty was scheduled for the next day. A 2.9 cm diameter tumor was detected in the tail of the pancreas on plain CT at the first visit and confirmed on enhanced CT soon after the hernia repair. A follow-up abdominal CT scan approximately 1 month later showed modest enlargement of the tumor to 3...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28122523/adjuvant-radiotherapy-improves-cause-specific-survival-in-stage-ii-not-stage-iii-mucinous-carcinoma-of-the-rectum
#6
Qingguo Li, Yaqi Li, Weixing Dai, Sheng Wang, Ye Xu, Xinxiang Li, Sanjun Cai
BACKGROUND: The effect of adjuvant radiotherapy on the survival outcomes of patients with mucinous rectal cancer remains unclear. This study evaluated the 5-year cause specific survival (CSS) of patients with mucinous rectal cancer after surgery to determine whether adjuvant radiotherapy conferred a survival benefit. METHODS: An analysis of the Surveillance, Epidemiology, and End Results (SEER)-registered database was conducted of patients presenting with mucinous rectal cancer between 2004 and 2011...
January 26, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28104993/synchronous-quintuple-primary-gastrointestinal-tract-malignancies-case-report
#7
Soo-Hong Kim, Byung-Soo Park, Hyun Sung Kim, Jae Hun Kim
Multiple primary malignancy is defined as two or more malignancies detected in an individual person. In particular, synchronous quintuple primary malignancy is extremely rare. A 52-year-old male with anal pain and intermittent blood-tinged stool was diagnosed with malignancies in the stomach, jejunum, ascending colon, transverse colon and rectum. He underwent a subtotal gastrectomy, segmental resection of the jejunum and total protocolectomy with end ileostomy. The postoperative pathologic findings were moderate differentiated gastric adenocarcinoma (pT1bN0M0, pStageIA), combined adenocarcinoma and neuroendocrine carcinoma of the jejunum (pT3N0M0, pStageIIA), three mucinous adenocarcinoma of the ascending colon (pT3N0M0, pStageIIA), transverse colon (pT1N0M0, pStageI) and rectum (pT3N1aM0, pStageIIIB)...
January 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28095874/clinicopathological-study-of-9-cases-of-prostate-cancer-involving-the-rectal-wall
#8
Tao Tang, Zhengduo Yang, Dan Zhang, Jie Qu, Guang Liu, Shiwu Zhang
BACKGROUND: Prostate cancer involving the rectal wall is rare and may lead to diagnostic pitfalls. CASE PRESENTATION: Out of 9504 patients with rectal tumors between January 2003 and January 2015, 9 patients (elderly with a mean age of 74 years) with prostate cancer involving the rectal wall were clinically misdiagnosed with rectal cancer. The lesions were located in the rectum, and included 3 circumferential rectal masses, 1 ulceration lesion, 1 crater-like mass, and 4 protruding lesions...
January 17, 2017: Diagnostic Pathology
https://www.readbyqxmd.com/read/28072710/metastatic-renal-clear-cell-carcinoma-to-the-rectum-lungs-ilium-and-lymph-nodes-a-case-report
#9
Guoyang Zheng, Hanzhong Li, Ji Li, Xuebin Zhang, Yushi Zhang, Xingcheng Wu
BACKGROUND: Renal cell carcinoma metastasizing to rectum is very rare, and the unusual metastatic sites should be paid attention to during the follow-up of renal cell carcinoma. CASE SUMMARY: We describe a case of a 65-year-old male who was diagnosed with metastatic renal cell carcinoma to rectum 10 years after the right radical nephrectomy. Histopathology and immunohistochemical examinations contribute to making differential diagnosis between rectal metastasis of renal cell carcinoma and primary rectal clear cell carcinoma...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28065369/the-stratification-of-severity-of-acute-radiation-proctopathy-after-radiotherapy-for-cervical-carcinoma-using-diffusion-weighted-mri
#10
Xiang Sheng Li, Hong Fang, Yunlong Song, Dechang Li, Yingjie Wang, Hongxian Zhu, Limin Meng, Ping Wang, Dong Wang, Hongxia Fan
OBJECTIVE: To determine whether diffusion-weighted imaging (DWI) can be used for quantitatively evaluating severity of acute radiation proctopathy after radiotherapy for cervical carcinoma. MATERIALS AND METHODS: One hundred and twenty-four patients with cervical carcinoma underwent MR examination including DWI before and after radiotherapy. Acute radiation proctopathy was classified into three groups (grade 0, grade I-II and grade III-IV) according to Toxicity Criteria of the Radiation Therapy Oncology Group (RTOG)...
February 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28064440/dietary-fibre-for-the-prevention-of-recurrent-colorectal-adenomas-and-carcinomas
#11
REVIEW
Yibo Yao, Tao Suo, Roland Andersson, Yongqing Cao, Chen Wang, Jingen Lu, Evelyne Chui
BACKGROUND: This is an update of the Cochrane review published in 2002.Colorectal cancer (CRC) is a major cause of morbidity and mortality in industrialised countries. Experimental evidence has supported the hypothesis that dietary fibre may protect against the development of CRC, although epidemiologic data have been inconclusive. OBJECTIVES: To assess the effect of dietary fibre on the recurrence of colorectal adenomatous polyps in people with a known history of adenomatous polyps and on the incidence of CRC compared to placebo...
January 8, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28058078/extramammary-paget-s-disease-of-anal-canal-associated-with-rectal-adenoma-without-invasive-carcinoma
#12
Vaibhav Chumbalkar, Timothy A Jennings, Sanaz Ainechi, Edward C Lee, Hwajeong Lee
Extramammary Paget's disease (EMPD) is a rare disease which is found in apocrine-rich locations such as anogenital region, axilla and rarely in other sites. Perianal EMPD is often reported as the involvement of perianal skin, but involvement of anal mucosa is very rare. Based on pathogenesis and association with either synchronous or metachronous malignancy, EMPD can be divided into primary and secondary types. Treatment approach for these two types of Paget's disease and their prognosis is different, thus it is important to make the distinction...
December 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/28052292/evaluation-for-the-clinical-efficacy-of-colon-capsule-endoscopy-in-the-detection-of-laterally-spreading-tumors
#13
COMPARATIVE STUDY
Atsushi Igawa, Shiro Oka, Shinji Tanaka, Ichiro Otani, Sayoko Kunihara, Kazuaki Chayama
BACKGROUND AND AIM: The manner in which colorectal lesions are being detected with PillCam COLON2 capsule endoscopy (CCE2) has markedly improved in recent days. However, limited data are available on CCE2 for detecting laterally spreading tumors (LSTs). The aim of this study was to compare CCE2 with optical colonoscopy (OC), which is currently the gold standard used in the detection of LSTs. METHODS: We performed a prospective, single-academic center study comparing CCE2 with OC in patients with LSTs diagnosed using OC, which was performed during the 3-month period prior to CCE2...
2017: Digestion
https://www.readbyqxmd.com/read/28048120/su-f-t-29-the-important-of-each-fraction-image-guided-planning-for-postoperative-hdr-brachytherapy-in-endometrial-carcinoma
#14
D Piriyasang, P Pattaranutaporn, K Manokhoon
PURPOSE: Cylindrical applicators are often used for postoperative HDRbrachytherapy in endometrial carcinoma. It has been considered that dosimetric variation between fractions for this treatment is minimal and might not be necessary to perform treatment planning for every fractions. At our institute, it is traditional to perform treatment planning with CT simulation on the first fraction and uses this plan for the rest of treatment. This study was aim to evaluate the errors of critical structure doses between the fractions when simulation and planning were done for first fraction only...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046679/su-f-t-257-comparison-study-of-the-biological-and-physical-optimization-for-cervical-carcinoma
#15
Z Feng, C Tao, J Zhu, G Yu, S Qin, Y Yin, D Li
PURPOSE: In this study, IMRT optimization based on biological related models were applied in the clinic for cervical carcinoma cases and the results were compared with the traditional physical optimization. METHODS: Twenty patients of advanced stage cervical carcinoma were selected in this study. The treatment plan was generated on each patient using both biological and physical optimized model respectively. Additionally, the biological optimization was based on two basic models for bladder and rectum: Poisson (adjustable parameters: alpha/beta, gamma, D50) and Lyman-Kutcher-Burman (adjustable parameters: m, n, D50)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28035461/is-early-colonoscopy-after-ct-diagnosed-diverticulitis-still-necessary
#16
Thomas Surya Suhardja, Shana Norhadi, Edward Zhenyu Seah, Stephen Rodgers-Wilson
PURPOSE: WHO GLOBOCAN 2012 data showed that Australia and New Zealand have the highest incidence rates of colorectal cancer in the world (Ferlay et al. 1). Current guidelines recommend that patients admitted for an episode of acute diverticulitis require an early follow-up colonoscopy to rule out colorectal malignancy as reported by Fozard et al. (Colorectal Dis 13:1-11, 2011). Recent studies however have indicated that this may not be warranted (Brar et al. Dis Colon rectum 56:1259-1264, 2013)...
December 29, 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28029590/a-new-short-daily-brachytherapy-schedule-in-postoperative-endometrial-carcinoma-preliminary-results
#17
Ángeles Rovirosa, Carlos Ascaso, Antonio Herreros, Joan Sánchez, Katarzyna Holub, Albert Camarasa, Sebastià Sabater, Gabriela Oses, Julia García-Miguel, Yamile Rivera, Meritxell Arenas
PURPOSE: To evaluate the preliminary results of vaginal-cuff relapses (VCR) and complications of a short brachytherapy (BT) schedule in postoperative endometrial carcinoma. METHODS AND MATERIALS: From September 2011 to December 2014, 102 patients were treated with postoperative BT for endometrial carcinoma. Seventy-four patients received a single 7 Gy dose after external beam irradiation (Group 1), and 28 intermediate-risk patients received three daily fractions of 6 Gy (Group 2)...
January 2017: Brachytherapy
https://www.readbyqxmd.com/read/28029448/long-term-results-from-a-prospective-database-on-high-dose-rate-hdr-interstitial-brachytherapy-for-primary-cervical-carcinoma
#18
Julia Fallon, Sang-Jung Park, Lisa Yang, Darlene Veruttipong, Mingle Zhang, Thanh Van, Pin-Chieh Wang, Alexandra M Fekete, Mauricio Cambeiro, Mitchell Kamrava, Michael L Steinberg, D Jeffrey Demanes
OBJECTIVE: Present long-term outcomes in primary cervical cancer treated with external beam and high dose rate interstitial brachytherapy. METHODS: High dose rate (HDR) interstitial (IS) brachytherapy (BT) and external beam (EBRT) were administered from 1992 to 2009 to 315 patients who were unsuitable for intracavitary (IC) BT alone. Histology was 89% squamous cell, 8% adenocarcinoma, and 3% adenosquamous. FIGO stage was I-14%, II-47%, III-34%, and IVA-5%. Median tumor size was 6cm...
October 29, 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/28028388/detection-of-cancer-stem-cells-in-colorectal-cancer-histopathological-and-immunohistochemical-study
#19
Nour El Hoda S Ismaiel, Walid M Sharaf, Dina O Helmy, Mona M Zaki, Manal A Badawi, Ahmed S A Soliman
BACKGROUND: Growing evidence supports the notion that the onset of tumorigenesis could occur through cancer stem cells (CSCs). These tumour cells show low proliferative rates, high self-renewal capacity, propensity to differentiate into active proliferating tumour cells & resistance to chemoradiotherapy thus, possibly causing local recurrences & metastasis formation. CD44 has been used as a marker to isolate CSCs from colorectal carcinoma (CRC). AIM: To investigate the immunohistochemical expression of cancer stem cells marker (CD44) in CRC and correlate its expression with the clinicopathological aspects, TNM staging and modified Dukes' classification...
December 15, 2016: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28001112/microwave-ablation-for-treatment-of-hepatic-neoplasia-in-five-dogs
#20
Toni Yang, J Brad Case, Sarah Boston, Michael J Dark, Beau Toskich
CASE DESCRIPTION 5 dogs between 9 and 11 years of age were evaluated for treatment of primary (n = 2) or metastatic (3) hepatic neoplasia. CLINICAL FINDINGS Patients were evaluated on an elective (n = 3) or emergency (2) basis. Two dogs with primary hepatic neoplasia were evaluated because of lethargy and inappetence. One dog was referred after an enlarged anal sac was detected via palpation per rectum during a routine physical examination. Two dogs were evaluated on an emergency basis because of lethargy and weakness, and hemoabdomen in the absence of a history of trauma was detected...
January 1, 2017: Journal of the American Veterinary Medical Association
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