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https://www.readbyqxmd.com/read/28715708/the-evaluation-of-brain-perfusion-spect-using-an-easy-z-score-imaging-system-in-the-mild-cognitive-impairment-subjects-with-brain-amyloid-%C3%AE-deposition
#1
Makoto Takemaru, Noriyuki Kimura, Yoshitake Abe, Megumi Goto, Etsuro Matsubara
OBJECTIVE: The analysis of (99)mTc-ECD single-photon emission computed tomography (SPECT) images using the easy Z-score imaging system (eZIS) program is useful for the diagnosis of early AD in daily medical practice. However, it remains unclear whether eZIS analysis can identify the amnestic mild cognitive impairment (MCI) subjects with brain amyloid-β deposition. The aim of this study was to evaluate the usefulness of an eZIS analysis for predicting amnestic MCI subjects with brain amyloid β deposition...
July 5, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28715661/cognitive-decline-and-brain-amyloid-%C3%AE-accumulation-across-3-years-in-adults-with-down-syndrome
#2
Sigan L Hartley, Benjamin L Handen, Darlynne Devenny, Iulia Mihaila, Regina Hardison, Patrick J Lao, William E Klunk, Peter Bulova, Sterling C Johnson, Bradley T Christian
Adults with Down syndrome (DS) have a high incidence of Alzheimer's disease (AD), providing a unique opportunity to explore the early, preclinical stages of AD neuropathology. We examined change in brain amyloid-β accumulation via the positron emission tomography tracer [11C] Pittsburgh compound B (PiB) across 2 data collection cycles, spaced 3 years apart, and decline in cognitive functioning in 58 adults with DS without clinical AD. PiB retention increased in the anterior cingulate gyrus, precuneus cortex, parietal cortex, and anterior ventral striatum...
June 2, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28712413/sleep-disturbance-and-kynurenine-metabolism-in-depression
#3
Hyong Jin Cho, Jonathan Savitz, Robert Dantzer, T Kent Teague, Wayne C Drevets, Michael R Irwin
OBJECTIVE: Although the interrelationships between sleep disturbance, inflammation, and depression have been found, molecular mechanisms that link these conditions are largely unknown. Kynurenine metabolism is hypothesized to be a key mechanism that links inflammation and depression. Inflammation activates the kynurenine pathway, leading to increases in 3-hydroxykynurenine (3HK) and quinolinic acid (QA), potentially neurotoxic metabolites, and decreases in kynurenic acid (KynA), a potentially neuroprotective compound...
August 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28709519/racial-discrimination-and-perinatal-sleep-quality
#4
Brittney Francis, Mark Klebanoff, Reena Oza-Frank
OBJECTIVE: This research examined the association between perceived everyday racial discrimination, as a psychosocial stressor, and perinatal sleep quality. DESIGN: Cross-sectional (N=640) and longitudinal associations (N=133) between everyday experiences of discrimination and sleep quality were examined using a pregnancy and postpartum data registry. PARTICIPANTS: We studied a sample of 640 unique women from the Perinatal Research Repository (PRR), a longitudinal study of mothers, fathers, and babies recruited from Nationwide Children's Hospital and The Ohio State University in Columbus, Ohio...
August 2017: Sleep Health
https://www.readbyqxmd.com/read/28709512/correlates-of-sleep-quality-and-sleep-duration-in-a-sample-of-urban-dwelling-elderly-nigerian-women
#5
Michael B Fawale, Isiaka Alani Ismaila, Adekunle F Mustapha, Morenikeji A Komolafe, Olanrewaju Ibigbami
OBJECTIVES: Aging, female sex, and urbanization increase the risk of sleep impairment. Sleep in urban-dwelling elderly African women has been sparsely studied. We studied the characteristics and correlates of sleep quality and habitual sleep duration in a primary care population of urban-living Nigerian women. METHODS: Sleep quality and sleep duration over the previous 1 month were estimated using the Pittsburgh Sleep Quality Index (PSQI). Excessive daytime sleepiness, risk of obstructive sleep apnea (OSA), and depressive symptoms were also assessed...
August 2017: Sleep Health
https://www.readbyqxmd.com/read/28709060/the-association-between-suicidal-ideation-and-sleep-quality-in-elderly-individuals-a-cross-sectional-study-in-shandong-china
#6
Yangyang Qian, Long Sun, Chengchao Zhou, Dandan Ge, Li Zhang
Previous studies have identified global associations between sleep quality and suicidal ideation. However, little is known regarding the relationship between sleep quality and suicidal ideation among Chinese older adults. We examined the relationship between sleep quality and suicidal ideation in older adults in China. A cross-sectional study was conducted in 3313 seniors in Shandong, China. Suicidal ideation was assessed using the interviewees' answers to the question "Have you ever seriously considered wanting to die?"...
July 10, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28708441/safe-monsplasty-technique
#7
Audrey Patoué, Antoine De Runz, Raphael Carloni, Sylvie Aillet, Eric Watier, Nicolas Bertheuil
INTRODUCTION: To improve their health and quality of life, obese patients undergo consultation after weight loss. In these patients, the sub-umbilical abdominal and pubic regions are often characterized by redundant skin, creating aesthetic and functional discomfort. Monsplasty is an important step in abdominoplasty or bodylift procedures. We report on an original technique used to correct deformity in the pubic region following weight loss. METHODS: All interventions were performed by the same surgeon between April and December 2015...
July 14, 2017: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/28708121/sex-differences-in-the-relationship-between-sleep-behavior-fish-consumption-and-depressive-symptoms-in-the-general-population-of-south-korea
#8
Atin Supartini, Taro Oishi, Nobuyuki Yagi
Sleep, fish consumption, and depression have a close relationship; however, the role of sex differences in sleep, fish consumption, and depression research is not yet well-established. This study aimed to examine whether the impact of bedtime, sleep-onset latency, sleep duration, sleep quality, and fish consumption on depressive symptoms differed in women and men. An online survey was conducted in South Korea with a stratified random sample of 600 participants between the ages of 20 and 69, whose gender and age were proportional to estimates of Korea's general population...
July 14, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28707741/randomized-clinical-trial-of-psychological-support-and-sleep-adjuvant-measures-for-postoperative-sleep-disturbance-in-patients-undergoing-oesophagectomy
#9
M Scarpa, E Pinto, E Saraceni, F Cavallin, M Parotto, R Alfieri, M T Nardi, M R Marchi, M Cagol, C Castoro
BACKGROUND: Major surgery such as oesophagectomy requires a postoperative stay in intensive care. Painful stimuli lead to sleep disturbance and impairment in quality of life. The aim of this study was to evaluate the effect of psychological counselling and sleep adjuvant measures on postoperative quality of sleep and quality of life. METHODS: This RCT was performed between January 2013 and October 2015. Patients undergoing oesophagectomy for cancer were randomized into one of four groups receiving: psychological counselling plus sleep adjuvant measures during the ICU stay; psychological counselling alone; sleep adjuvant measures alone during the ICU stay; or standard care...
July 14, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28706322/respirable-dust-measured-downwind-during-rock-dust-application
#10
M L Harris, J Organiscak, S Klima, I E Perera
The Pittsburgh Mining Research Division of the U.S. National Institute for Occupational Safety and Health (NIOSH) conducted underground evaluations in an attempt to quantify respirable rock dust generation when using untreated rock dust and rock dust treated with an anticaking additive. Using personal dust monitors, these evaluations measured respirable rock dust levels arising from a flinger-type application of rock dust on rib and roof surfaces. Rock dust with a majority of the respirable component removed was also applied in NIOSH's Bruceton Experimental Mine using a bantam duster...
May 2017: Mining Engineering
https://www.readbyqxmd.com/read/28704743/sleep-abnormalities-in-juvenile-myoclonic-epilepsy-a-sleep-questionnaire-and-polysomnography-based-study
#11
Sujata Roshan, Vinod Puri, Neera Chaudhry, Anu Gupta, Sumit Kumar Rabi
PURPOSE: To evaluate the quality of sleep, its architecture and occurrence of epileptiform discharges with their distribution across various stages of sleep in patients of Juvenile myoclonic epilepsy (JME), both drug naïve as well as those already on treatment. METHODS: 99 patients of JME [36 drug naïve, 63 on antiepileptic drug(s) (AED)], and 30 healthy controls were recruited. Sleep quality and daytime sleepiness were evaluated with Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS), respectively...
June 28, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28704594/critical-diagnoses-in-cytopathology-experience-at-a-large-medical-center
#12
Juan Xing, Lindsey Seigh, Sara E Monaco, N Paul Ohori, Samuel A Yousem, Rajnikant Amin, Liron Pantanowitz
BACKGROUND: Critical values have been well established and accepted in laboratory medicine, but to the authors' knowledge are less well accepted in anatomic pathology. Herein, the authors used a reporting process whereby reports with critical diagnoses were coded to ensure that the patient's clinical team was promptly notified electronically of this finding. The aim of the current study was to determine whether this coding mechanism was used appropriately for critical cytopathology diagnoses in the study health care system...
July 13, 2017: Cancer
https://www.readbyqxmd.com/read/28703951/secondary-prevention-of-chronic-ptsd-by-early-and-short-term-administration-of-escitalopram-a-prospective-randomized-placebo-controlled-double-blind-trial
#13
Joseph Zohar, Leah Fostick, Alzabeta Juven-Wetzler, Zeev Kaplan, Hadar Shalev, Gavriel Schreiber, Natalie Miroshnik, Arieh Y Shalev, Dan J Stein, Soraya Seedat, Sharain Suliman, Ehud Klein
OBJECTIVE: Prospective studies have not identified a viable pharmacologic strategy for secondary prevention of posttraumatic stress disorder (PTSD). The authors examined whether preventive intervention via early and short-term administration of a selective serotonin reuptake inhibitor (SSRI), within 1 month of exposure to a traumatic event (before diagnosis of PTSD could be made), may reduce the severity of PTSD symptoms according to DSM-IV at 13 months' follow-up. METHODS: Over 25,000 screening calls to patients referred to an emergency department for a traumatic event performed between June 2006 and December 2008 yielded 353 participants who were recruited within the month following a traumatic event ...
July 11, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28701993/no-impaired-glucose-tolerance-in-primary-insomnia-patients-with-normal-results-of-polysomnography
#14
Johanna Tschepp, Christoph J Lauer, Johanna Wilde-Frenz, Thomas Pollmächer
BACKGROUND: According to recent studies, sleep restriction and disruption both have a prominent negative influence on glucose metabolism. This could also be shown in sleep disorders, such as sleep apnea and the restless legs syndrome. However, similar studies regarding insomnia have not been that consistent, yet. Moreover, most previous studies did not include objective polysomnography (PSG) data. METHODS: Patients with primary insomnia (N = 17) and healthy controls (N = 15) were investigated using psychometric tests such as the Epworth Sleepiness Scale and the Pittsburgh sleep quality index (PSQI)...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28700701/development-and-validation-of-the-maugeri-sleep-quality-and-distress-inventory-masqudi-17
#15
Elisa Morrone, Cinzia Sguazzin, Giorgio Bertolotti, Andrea Giordano, Alberto Braghiroli, Gian Luigi Balestroni, Raffaele Manni, Luigi Ferini Strambi, Vincenza Castronovo, Marco Zucconi, Fabrizio De Carli, Eleonora Pinna, Marcella Ottonello, Ines Giorgi, Michele Terzaghi, Sara Marelli, Francesco Fanfulla
OBJECTIVES: The aim of this study was to develop and validate a questionnaire designed to measure the impact of sleep impairment on emotional distress in patients with various sleep disorders. METHODS: Five experts created an item data-bank pertaining to sleep-related psychological symptoms and somatic perceptions. Fifty patients in two focus groups examined each item for: a) word clarity (indicating any ambiguity of interpretation) and b) appropriateness for the target population...
2017: PloS One
https://www.readbyqxmd.com/read/28699332/prevalence-of-restless-legs-syndrome-in-migraine-patients-a-case-control-study-analysis-of-risk-factors-for-restless-legs-syndrome-in-migraine-patients
#16
Mariarosaria Valente, Francesco Janes, Valentina Russo, Augusto Fontana, Alessia Travanut, Martina Sommaro, Giessica Canal, Carolina Gentile, Gian Luigi Gigli
BACKGROUND: Restless legs syndrome (RLS) is a sensorimotor disorder. It can be idiopathic, associated to other diseases or to pharmacologic treatments. RLS has been reported to occur more frequently in migraine patients, but a clear pathogenetic link seems still under debate. We aimed to evaluate RLS prevalence in migraine, impact on sleep quality and the main clinical determinants of this association. METHODS: Migraine patients and age- and sex-matched controls were enrolled from 1(st) January 2011 to 30(th) December 2012...
July 2017: Headache
https://www.readbyqxmd.com/read/28698133/randomized-controlled-trial-of-internal-and-external-targeted-temperature-management-methods-in-post-cardiac-arrest-patients
#17
Xinqi Look, Huihua Li, Mingwei Ng, Eric Tien Siang Lim, Sohil Pothiawala, Kenneth Boon Kiat Tan, Duu Wen Sewa, Nur Shahidah, Pin Pin Pek, Marcus Eng Hock Ong
BACKGROUND: Targeted temperature management post-cardiac arrest is currently implemented using various methods, broadly categorized as internal and external. This study aimed to evaluate survival-to-hospital discharge and neurological outcomes (Glasgow-Pittsburgh Score) of post-cardiac arrest patients undergoing internal cooling verses external cooling. METHODOLOGY: A randomized controlled trial of post-resuscitation cardiac arrest patients was conducted from October 2008-September 2014...
July 5, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28697559/depressive-symptoms-and-tau-accumulation-in-the-inferior-temporal-lobe-and-entorhinal-cortex-in-cognitively-normal-older-adults-a-pilot-study
#18
Jennifer R Gatchel, Nancy J Donovan, Joseph J Locascio, Aaron P Schultz, J Alex Becker, Jasmeer Chhatwal, Kathryn V Papp, Rebecca E Amariglio, Dorene M Rentz, Deborah Blacker, Reisa A Sperling, Keith A Johnson, Gad A Marshall
BACKGROUND: Depressive symptoms are common in older adults and associated with increased morbidity and cognitive decline. These symptoms occur during preclinical and prodromal stages of Alzheimer's disease (AD), but their relationship to tau, one of the main AD proteinopathies, is poorly understood. OBJECTIVE: The objective of this study was to investigate the cross-sectional association between depressive symptoms and cerebral tau [18F T807 (also known as 18F-AV-1451) tau positron emission tomography (PET) imaging] in cognitively normal (CN) older adults...
July 4, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28697489/subjective-sleep-disturbance-in-chinese-adults-with-epilepsy-associations-with-affective-symptoms
#19
Yeru Shen, Mengmeng Zhang, Yu Wang, Lanlan Wang, Xiangjun Xu, Gairong Xiao, Jing Chen, Ting Zhang, Nong Zhou
BACKGROUND: As well as being a very common neurological disease worldwide, epilepsy significantly impairs patients' emotional, behavioral, and cognitive functioning. Sleep disturbances are the most frequent complaint in patients with epilepsy. The present study assesses the impact of a range of affective symptoms on subjective sleep quality and sleep disturbances in Chinese adults with epilepsy. METHODS: Adults with epilepsy who visited our epilepsy clinic from July 2015 to March 2016 were enrolled in our study...
July 1, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28697154/interfacility-transport-shock-index-is-associated-with-decreased-survival-in-children
#20
Ryan M Jennings, Bradley A Kuch, Kathryn A Felmet, Richard A Orr, Joseph A Carcillo, Ericka L Fink
BACKGROUND: Shock index, the ratio of heart rate to systolic blood pressure that changes with age, is associated with mortality in adults after trauma and in children with sepsis. We assessed the utility of shock index to predict sepsis diagnosis and survival in children requiring interfacility transport to a tertiary care center. METHODS: We studied children aged 1 month to 21 years who had at least 2 sets of vital signs recorded during interfacility transport to the Children's Hospital of Pittsburgh by our critical care transport team...
July 11, 2017: Pediatric Emergency Care
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