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https://www.readbyqxmd.com/read/28525774/development-and-validation-of-a-physical-model-to-investigate-the-biomechanics-of-infant-head-impact
#1
M Jones, D Darwall, G Khalid, R Prabhu, A Kemp, O Arthurs, P Theobald
Head injury in childhood is the single most common cause of death or permanent disability from injury. However, despite its frequency and significance, there is little understanding of the response of a child's head to injurious loading. This is a significant limitation when making early diagnoses, informing clinical and/or forensic management or injury prevention strategies. With respect to impact vulnerability, current understanding is predominantly based on a few post-mortem-human-surrogate (PMHS) experiments...
April 13, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28524375/bioprinted-osteogenic-and-vasculogenic-patterns-for-engineering-3d-bone-tissue
#2
Batzaya Byambaa, Nasim Annabi, Kan Yue, Grissel Trujillo-de Santiago, Mario Moisés Alvarez, Weitao Jia, Mehdi Kazemzadeh-Narbat, Su Ryon Shin, Ali Tamayol, Ali Khademhosseini
Fabricating 3D large-scale bone tissue constructs with functional vasculature has been a particular challenge in engineering tissues suitable for repairing large bone defects. To address this challenge, an extrusion-based direct-writing bioprinting strategy is utilized to fabricate microstructured bone-like tissue constructs containing a perfusable vascular lumen. The bioprinted constructs are used as biomimetic in vitro matrices to co-culture human umbilical vein endothelial cells and bone marrow derived human mesenchymal stem cells in a naturally derived hydrogel...
May 19, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28523275/online-detection-of-peroxidase-using-3d-printing-active-magnetic-mixing-and-spectra-analysis
#3
Shanshan Bai, Chengqi Gan, Gaozhe Cai, Lei Wang, Mingyong Chen, Qingan Han, Jianhan Lin
A new method for online detection of peroxidase (POD) using 3D printing, active magnetic mixing, fluidic control, and optical detection was developed and demonstrated in this study. The proposed POD detection system consisted of a 3D printing and active magnetic mixing based fluidic chip for online catalytic reaction, an optical detector with a fluidic flow cell for quantitative determination of the final catalysate, and a single-chip microcontroller based controller for automatic control of two rotating magnetic fields and four precise peristaltic pumps...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28523082/three-dimensional-printing-custom-made-implants-for-craniomaxillofacial-reconstructive-surgery
#4
REVIEW
Mariana Matias, Horácio Zenha, Horácio Costa
Craniomaxillofacial reconstructive surgery is a challenging field. First it aims to restore primary functions and second to preserve craniofacial anatomical features like symmetry and harmony. Three-dimensional (3D) printed biomodels have been widely adopted in medical fields by providing tactile feedback and a superior appreciation of visuospatial relationship between anatomical structures. Craniomaxillofacial reconstructive surgery was one of the first areas to implement 3D printing technology in their practice...
June 2017: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/28520846/patient-specific-augmentation-rhinoplasty-using-a-three-dimensional-simulation-program-and-three-dimensional-printing
#5
Yim Don Choi, Youngjun Kim, EunSoo Park
Background: The convergence of three-dimensional (3D) simulation, tissue engineering, and 3D printing technology is creating a paradigm shift in plastic surgery. In augmentation rhinoplasty, determining the ideal material and design method has been a critical issue for many years. Thus, these technologies are expected to make important contributions to augmentation rhinoplasty. Objectives: We sought to validate the feasibility of the 3D carving simulation and patient-specific implant fabrication system (3D carving system) in a clinical trial using reproducibility tests...
May 17, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28520396/simultaneous-on-line-monitoring-of-multiple-reactions-using-a-miniature-mass-spectrometer
#6
Christopher J Pulliam, Ryan M Bain, Heather L Osswald, Dalton T Snyder, Patrick W Fedick, Stephen T Ayrton, Tawnya G Flick, R Graham Cooks
Advanced methods of chemical sampling using miniature mass spectrometer technology are applied to monitor slow reactions at a frequency of ca 180 hr-1. There is no detectable sample carryover and in-line derivatization is used in the case of poorly ionizing compounds. Moreover, we demonstrate high reproducibility with a relative error of less than 10% for major com-ponents. Monitoring is enabled using a continuous-flow nano-electrospray (CF-nESI) probe contained in a custom-built 3D-printed rotary holder. The holder position is automatically set using a stepper motor controlled by a microcontroller...
May 18, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28520334/kidney-anatomy-three-dimensional-3d-printed-pelvicalyceal-system-models-of-the-collector-system-improve-the-diagnosis-and-treatment-of-stone-disease
#7
EDITORIAL
Luciano A Favorito
No abstract text is available yet for this article.
May 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28518077/inkjet-printed-polyvinyl-alcohol-multilayers
#8
Iulia Salaoru, Zuoxin Zhou, Peter Morris, Gregory J Gibbons
Inkjet printing is a modern method for polymer processing, and in this work, we demonstrate that this technology is capable of producing polyvinyl alcohol (PVOH) multilayer structures. A polyvinyl alcohol aqueous solution was formulated. The intrinsic properties of the ink, such as surface tension, viscosity, pH, and time stability, were investigated. The PVOH-based ink was a neutral solution (pH 6.7) with a surface tension of 39.3 mN/m and a viscosity of 7.5 cP. The ink displayed pseudoplastic (non-Newtonian shear thinning) behavior at low shear rates, and overall, it demonstrated good time stability...
May 11, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28518066/scaled-anatomical-model-creation-of-biomedical-tomographic-imaging-data-and-associated-labels-for-subsequent-sub-surface-laser-engraving-ssle-of-glass-crystals
#9
Aislinn M Betts, Matthew T McGoldrick, Christopher R Dethlefs, Justin Piotrowicz, Tony Van Avermaete, Jeff Maki, Steve Gerstler, W M Leevy
Biomedical imaging modalities like computed tomography (CT) and magnetic resonance (MR) provide excellent platforms for collecting three-dimensional data sets of patient or specimen anatomy in clinical or preclinical settings. However, the use of a virtual, on-screen display limits the ability of these tomographic images to fully convey the anatomical information embedded within. One solution is to interface a biomedical imaging data set with 3D printing technology to generate a physical replica. Here we detail a complementary method to visualize tomographic imaging data with a hand-held model: Sub Surface Laser Engraving (SSLE) of crystal glass...
April 25, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28515424/a-split-ring-resonator-dielectric-probe-for-near-field-dielectric-imaging
#10
Dmitry Isakov, Chris J Stevens, Flynn Castles, Patrick S Grant
A single split-ring resonator (SRR) probe for 2D surface mapping and imaging of relative dielectric permittivity for the characterisation of composite materials has been developed. The imaging principle, the analysis and the sensitivity of the SRR surface dielectric probe data is described. The surface dielectric properties of composite materials in the frequency range 1-3 GHz have been measured based on the magnetic resonance frequency of the transmission loss of the SRR dielectric probe when in contact with the surface...
May 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28514229/an-open-source-wireless-capable-miniature-microscope-system
#11
William A Liberti, L Nathan Perkins, Daniel P Leman, Timothy J Gardner
OBJECTIVE: Fluorescence imaging through head-mounted microscopes in freely behaving animals is becoming a standard method to study neural circuit function. Flexible, open-source designs are needed to spur evolution of the method. APPROACH: We describe a miniature microscope for single-photon fluorescence imaging in freely behaving animals. The device is made from 3D printed parts and off-the-shelf components. These microscopes weigh less than 1.8 g, can be configured to image a variety of fluorophores, and can be used wirelessly or in conjunction with active commutators...
May 17, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28513855/technical-note-system-for-evaluating-local-hypothermia-as-a-radioprotector-of-the-rectum-in-a-small-animal-model
#12
Brian A Hrycushko, Chenchen Bing, Cecil Futch, Michelle Wodzak, Strahinja Stojadinovic, Paul M Medin, Rajiv Chopra
PURPOSE: The protective effects of induced or even accidental hypothermia on the human body are widespread with several medical uses currently under active research. In vitro experiments using human cell lines have shown hypothermia provides a radioprotective effect that becomes more pronounced at large, single-fraction doses common to stereotactic body radiotherapy (SBRT) and stereotactic radiosurgery (SRS) treatments. This work describes the development of a system to evaluate local hypothermia for a radioprotive effect of the rat rectum during a large dose of radiation relevant to prostate SBRT...
May 17, 2017: Medical Physics
https://www.readbyqxmd.com/read/28512850/in-situ-handheld-3d-bioprinting-for-cartilage-regeneration
#13
Claudia Di Bella, Serena Duchi, Cathal D O'Connell, Romane Blanchard, Cheryl Augustine, Zhilian Yue, Fletcher Thompson, Christopher Richards, Stephen Beirne, Carmine Onofrillo, Sebastien H Bauquier, Stewart D Ryan, Peter Pivonka, Gordon G Wallace, Peter F Choong
Articular cartilage injuries experienced at an early age can lead to the development of osteoarthritis later in life. In situ 3D printing is an exciting and innovative bio-fabrication technology that enables the surgeon to deliver tissue- engineering techniques at the time and location of need. We have created a hand- held 3D printing device (Biopen) that allows the simultaneous co-axial extrusion of bioscaffold and cultured cells directly into the cartilage defect in vivo in a single session surgery. This pilot study assesses the ability of the Biopen to repair a full thickness chondral defect and the early outcomes in cartilage regeneration, and compares these results to other treatments in a large animal model...
May 17, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28512008/3d-printing-and-modelling-of-customized-implants-and-surgical-guides-for-non-human-primates
#14
Xing Chen, Jessy K Possel, Catherine Wacongne, Anne F van Ham, P Christiaan Klink, Pieter R Roelfsema
BACKGROUND: Primate neurobiologists use chronically implanted devices such as pedestals for head stabilization and chambers to gain access to the brain and study its activity. Such implants are skull-mounted, and made from a hard, durable material, such as titanium. NEW METHOD: Here we present a low-cost method of creating customized 3D-printed cranial implants that are tailored to the anatomy of individual animals. We performed pre-surgical computed tomography (CT) and magnetic resonance (MR) scans to generate three-dimensional (3D) models of the skull and brain...
May 13, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28509899/a-bioprosthetic-ovary-created-using-3d-printed-microporous-scaffolds-restores-ovarian-function-in-sterilized-mice
#15
Monica M Laronda, Alexandra L Rutz, Shuo Xiao, Kelly A Whelan, Francesca E Duncan, Eric W Roth, Teresa K Woodruff, Ramille N Shah
Emerging additive manufacturing techniques enable investigation of the effects of pore geometry on cell behavior and function. Here, we 3D print microporous hydrogel scaffolds to test how varying pore geometry, accomplished by manipulating the advancing angle between printed layers, affects the survival of ovarian follicles. 30° and 60° scaffolds provide corners that surround follicles on multiple sides while 90° scaffolds have an open porosity that limits follicle-scaffold interaction. As the amount of scaffold interaction increases, follicle spreading is limited and survival increases...
May 16, 2017: Nature Communications
https://www.readbyqxmd.com/read/28508523/the-effect-of-sodium-hypochlorite-concentration-and-irrigation-needle-extension-on-biofilm-removal-from-a-simulated-root-canal-model
#16
Saifalarab A Mohmmed, Morgana E Vianna, Matthew R Penny, Stephen T Hilton, Jonathan C Knowles
To investigate the effect of sodium hypochlorite concentration and needle extension on removal of Enterococcus faecalis biofilm, sixty root canal models were 3D printed. Biofilms were grown on the apical 3 mm of the canal for 10 days. Irrigation for 60s with 9 mL of either 5.25% or 2.5% NaOCl or water was performed using a needle inserted either 3 or 2 mm from the canal terminus and imaged using fluorescence microscopy and residual biofilm percentages were calculated using imaging software. The data were analysed using analysis of covariance and two-sample t-tests...
May 16, 2017: Australian Endodontic Journal: the Journal of the Australian Society of Endodontology Inc
https://www.readbyqxmd.com/read/28508071/self-assembled-micro-organogels-for-3d-printing-silicone-structures
#17
Christopher S O'Bryan, Tapomoy Bhattacharjee, Samuel Hart, Christopher P Kabb, Kyle D Schulze, Indrasena Chilakala, Brent S Sumerlin, W Gregory Sawyer, Thomas E Angelini
The widespread prevalence of commercial products made from microgels illustrates the immense practical value of harnessing the jamming transition; there are countless ways to use soft, solid materials that fluidize and become solid again with small variations in applied stress. The traditional routes of microgel synthesis produce materials that predominantly swell in aqueous solvents or, less often, in aggressive organic solvents, constraining ways that these exceptionally useful materials can be used. For example, aqueous microgels have been used as the foundation of three-dimensional (3D) bioprinting applications, yet the incompatibility of available microgels with nonpolar liquids, such as oils, limits their use in 3D printing with oil-based materials, such as silicone...
May 2017: Science Advances
https://www.readbyqxmd.com/read/28507143/controllable-load-sharing-for-soft-adhesive-interfaces-on-three-dimensional-surfaces
#18
Sukho Song, Dirk-Michael Drotlef, Carmel Majidi, Metin Sitti
For adhering to three-dimensional (3D) surfaces or objects, current adhesion systems are limited by a fundamental trade-off between 3D surface conformability and high adhesion strength. This limitation arises from the need for a soft, mechanically compliant interface, which enables conformability to nonflat and irregularly shaped surfaces but significantly reduces the interfacial fracture strength. In this work, we overcome this trade-off with an adhesion-based soft-gripping system that exhibits enhanced fracture strength without sacrificing conformability to nonplanar 3D surfaces...
May 15, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28506939/printed-mdct-3d-models-for-prediction-of-left-atrial-appendage-laa-occluder-device-size-a-feasibility-study
#19
Orly Goitein, Noam Fink, Victor Guetta, Roy Beinart, Yafim Brodov, Eli Konen, David Goitein, Elio Di Segni, Avishay Grupper, Michael Glikson
AIMS: Trans-esophageal echocardiography (TEE) and MDCT currently serve as imaging modalities for left atrial appendage (LAA) occlusion pre-procedural planning. We assessed the feasibility of multi-detector CT (MDCT) based models to predict the correct size of device for LAA occlusion procedures. METHODS AND RESULTS: Patients planned for LAA occlusion underwent MDCT before implantation, which was used for creating and printing 3D LAA models. Three cardiologists evaluated the 3D models and predicted the correct size of the device by manual manipulation, these predictions were compared with the actual device implanted during the procedure...
May 16, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28504546/use-of-a-3d-printed-abdominal-compression-device-to-facilitate-ct-fluoroscopy-guided-percutaneous-interventions
#20
Yan Epelboym, Paul B Shyn, Ahmed Hosny, Tatiana Kelil, Jeffrey Forris Beecham Chick, Nikunj R Chauhan, Beth Ripley, Richard D Nawfel, Francis J Scholz
OBJECTIVE: The purpose of this article is to describe a handheld external compression device used to facilitate CT fluoroscopy-guided percutaneous interventions in the abdomen. CONCLUSION: The device was designed with computer-aided design software to modify an existing gastrointestinal fluoroscopy compression device and was constructed by 3D printing. This abdominal compression device facilitates access to interventional targets, and its use minimizes radiation exposure of radiologists...
May 15, 2017: AJR. American Journal of Roentgenology
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