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https://www.readbyqxmd.com/read/28654068/fabrication-of-3d-carbon-microelectromechanical-systems-c-mems
#1
Bidhan Pramanick, Sergio O Martinez-Chapa, Marc Madou, Hyundoo Hwang
A wide range of carbon sources are available in nature, with a variety of micro-/nanostructure configurations. Here, a novel technique to fabricate long and hollow glassy carbon microfibers derived from human hairs is introduced. The long and hollow carbon structures were made by the pyrolysis of human hair at 900 °C in a N2 atmosphere. The morphology and chemical composition of natural and pyrolyzed human hairs were investigated using scanning electron microscopy (SEM) and electron-dispersive X-ray spectroscopy (EDX), respectively, to estimate the physical and chemical changes due to pyrolysis...
June 17, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28653854/a-thermogelling-supramolecular-hydrogel-with-sponge-like-morphology-as-a-cytocompatible-bioink
#2
Thomas Lorson, Sebastian Jaksch, Michael M Lübtow, Tomasz Jüngst, Jürgen Groll, Tessa Lühmann, Robert Luxenhofer
Biocompatible polymers that form thermoreversible supramolecular hydrogels have gained great interest in biomaterials research and tissue engineering. When favorable rheological properties are achieved at the same time, they are particularly promising candidates as material that allow for the printing of cells, so-called bioinks. We synthesized a novel thermogelling block copolymer and investigated the rheological properties of its aqueous solution by viscosimetry and rheology. The polymers undergo thermogelation between room temperature and body temperature, form transparent hydrogels of surprisingly high strength (G' > 1000 Pa) and show rapid and complete shear recovery after stress...
June 27, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28653043/bioactive-polymeric-scaffolds-for-tissue-engineering
#3
Scott Stratton, Namdev B Shelke, Kazunori Hoshino, Swetha Rudraiah, Sangamesh G Kumbar
A variety of engineered scaffolds have been created for tissue engineering using polymers, ceramics and their composites. Biomimicry has been adopted for majority of the three-dimensional (3D) scaffold design both in terms of physicochemical properties, as well as bioactivity for superior tissue regeneration. Scaffolds fabricated via salt leaching, particle sintering, hydrogels and lithography have been successful in promoting cell growth in vitro and tissue regeneration in vivo. Scaffold systems derived from decellularization of whole organs or tissues has been popular due to their assured biocompatibility and bioactivity...
December 2016: Bioactive Materials
https://www.readbyqxmd.com/read/28652298/a-patient-specific-intracranial-aneurysm-model-with-endothelial-lining-a-novel-in-vitro-approach-to-bridge-the-gap-between-biology-and-flow-dynamics
#4
Naoki Kaneko, Toshihiro Mashiko, Katsunari Namba, Satoshi Tateshima, Eiju Watanabe, Kensuke Kawai
OBJECTIVES: To develop an in vitro model for studying the biological effect of complex-flow stress on endothelial cells in three-dimensional (3D) patient-specific vascular geometry. MATERIALS AND METHODS: A vessel replica was fabricated with polydimethylsiloxanes using 3D printing technology from vascular image data acquired by rotational angiography. The vascular model was coated with fibronectin and immersed in a tube filled with a cell suspension of endothelium, and then cultured while being slowly rotated in three dimensions...
June 26, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28652126/patient-specific-3d-printed-cardiac-model-for-percutaneous-left-atrial-appendage-occlusion
#5
Beatriz Vaquerizo, Carmen Escabias, Daniela Dubois, Gorka Gómez, Manuel Barreiro-Pérez, Ignacio Cruz-González
No abstract text is available yet for this article.
June 23, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28651145/polymer-structure-property-requirements-for-stereolithographic-3d-printing-of-soft-tissue-engineering-scaffolds
#6
REVIEW
Ryan J Mondschein, Akanksha Kanitkar, Christopher B Williams, Scott S Verbridge, Timothy E Long
This review highlights the synthesis, properties, and advanced applications of synthetic and natural polymers 3D printed using stereolithography for soft tissue engineering applications. Soft tissue scaffolds are of great interest due to the number of musculoskeletal, cardiovascular, and connective tissue injuries and replacements humans face each year. Accurately replacing or repairing these tissues is challenging due to the variation in size, shape, and strength of different types of soft tissue. With advancing processing techniques such as stereolithography, control of scaffold resolution down to the μm scale is achievable along with the ability to customize each fabricated scaffold to match the targeted replacement tissue...
June 6, 2017: Biomaterials
https://www.readbyqxmd.com/read/28650971/a-lab-on-phone-instrument-with-varifocal-microscope-via-a-liquid-actuated-aspheric-lens-lal
#7
Yiin-Kuen Fuh, Zheng-Hong Lai, Li-Han Kau, Hung-Jui Huang
In this paper, we introduce a novel concept of liquid-actuated aspheric lens (LAL) with a built-in aspheric polydimethylsiloxane lens (APL) to enable the design of compact optical systems with varifocal microscopic imaging. The varifocal lens module consists of a sandwiched structures such as 3d printed syringe pump functionally serves as liquid controller. Other key components include two acrylic cylinders, a rigid separator, a APL/membrane composite (APLMC) embedded PDMS membrane. In functional operation, the fluidic controller was driven to control the pressure difference and ALPMC deformation...
2017: PloS One
https://www.readbyqxmd.com/read/28650141/flexible-and-foldable-fully-printed-carbon-black-conductive-nanostructures-on-paper-for-high-performance-electronic-electrochemical-and-wearable-devices
#8
Murilo Santhiago, Cátia C Côrrea, Juliana Silva Bernardes, Mariane Peres Pereira, Letícia J M Oliveira, Mathias Strauss, Carlos César Bof Bufon
In this work, we demonstrate the first example of fully-printed carbon nanomaterials on paper with unique features, aiming the fabrication of functional electronic and electrochemical devices. Bare and modified inks were prepared by combining carbon black and cellulose acetate to achieve high-performance conductive tracks with low sheet resistance. The carbon black tracks withstand extremely high folding cycles (> 20000 cycles), a new record-high with a response loss of less than 10%. The conductive tracks can also be used as 3D paper-based electrochemical cells with high heterogeneous rate constants - a feature that opens a myriad of electrochemical applications...
June 26, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28649209/map-learning-with-a-3d-printed-interactive-small-scale-model-improvement-of-space-and-text-memorization-in-visually-impaired-students
#9
Stéphanie Giraud, Anke M Brock, Marc J-M Macé, Christophe Jouffrais
Special education teachers for visually impaired students rely on tools such as raised-line maps (RLMs) to teach spatial knowledge. These tools do not fully and adequately meet the needs of the teachers because they are long to produce, expensive, and not versatile enough to provide rapid updating of the content. For instance, the same RLM can barely be used during different lessons. In addition, those maps do not provide any interactivity, which reduces students' autonomy. With the emergence of 3D printing and low-cost microcontrollers, it is now easy to design affordable interactive small-scale models (SSMs) which are adapted to the needs of special education teachers...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28649159/initial-simulated-ffr-investigation-using-flow-measurements-in-patient-specific-3d-printed-coronary-phantoms
#10
Lauren Shepard, Kelsey Sommer, Richard Izzo, Alexander Podgorsak, Michael Wilson, Zaid Said, Frank J Rybicki, Dimitrios Mitsouras, Stephen Rudin, Erin Angel, Ciprian N Ionita
PURPOSE: Accurate patient-specific phantoms for device testing or endovascular treatment planning can be 3D printed. We expand the applicability of this approach for cardiovascular disease, in particular, for CT-geometry derived benchtop measurements of Fractional Flow Reserve, the reference standard for determination of significant individual coronary artery atherosclerotic lesions. MATERIALS AND METHODS: Coronary CT Angiography (CTA) images during a single heartbeat were acquired with a 320×0...
February 11, 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28649158/implementation-of-material-decomposition-using-an-emccd-and-cmos-based-micro-ct-system
#11
Alexander R Podgorsak, Sv Setlur Nagesh, Daniel R Bednarek, Stephen Rudin, Ciprian N Ionita
This project assessed the effectiveness of using two different detectors to obtain dual-energy (DE) micro-CT data for the carrying out of material decomposition. A micro-CT coupled to either a complementary metal-oxide semiconductor (CMOS) or an electron multiplying CCD (EMCCD) detector was used to acquire image data of a 3D-printed phantom with channels filled with different materials. At any instance, materials such as iohexol contrast agent, water, and platinum were selected to make up the scanned object...
February 11, 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28649157/use-of-patient-specific-3d-printed-neurovascular-phantoms-to-evaluate-the-clinical-utility-of-a-high-resolution-x-ray-imager
#12
S V Setlur Nagesh, M Russ, C N Ionita, D Bednarek, S Rudin
Modern 3D printing technology can fabricate vascular phantoms based on an actual human patient with a high degree of precision facilitating a realistic simulation environment for an intervention. We present two experimental setups using 3D printed patient-specific neurovasculature to simulate different disease anatomies. To simulate the human neurovasculature in the Circle of Willis, patient-based phantoms with aneurysms were 3D printed using a Objet Eden 260V printer. Anthropomorphic head phantoms and a human skull combined with acrylic plates simulated human head bone anatomy and x-ray attenuation...
February 11, 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28648718/an-implantable-two-axis-micromanipulator-made-with-a-3d-printer-for-recording-neural-activity-in-free-swimming-fish
#13
Loranzie S Rogers, Jacey C Van Wert, Allen F Mensinger
BACKGROUND: Chronically implanted electrodes allow monitoring neural activity from free moving animals. While a wide variety of implanted headstages, microdrives and electrodes exist for terrestrial animals, few have been developed for use with aquatic animals. NEW METHOD: A two axis micromanipulator was fabricated with a Formlabs 3D printer for implanting electrodes into free-swimming oyster toadfish (Opsanus tau). The five piece manipulator consisted of a base, body, electrode holder, manual screw drive and locking nut...
June 22, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28648046/a-printed-equilibrium-dialysis-device-with-integrated-membranes-for-improved-binding-affinity-measurements
#14
Cody Pinger, Andrew Heller, Dana M Spence
Equilibrium dialysis is a simple and effective technique used for investigating the binding of small molecules and ions to proteins. A 3D-printer was used to create a device capable of measuring binding constants between a protein and a small ion based on equilibrium-dialysis. Specifically, the technology described here enables the user to customize an equilibrium dialysis device to fit their own experiments by choosing membranes of various material and molecular-weight cutoff values. The device has dimensions similar to that of a standard 96-well plate, thus being amenable to automated sample handlers and multi-channel pipettes...
June 25, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28647828/3d-printing-of-severe-hypertrophic-cardiomyopathy-in-a-child-with-rasopathy
#15
N F Johnston, T Prendiville, C J McMahon
We describe the use of 3D printing in conjunction with echocardiography in assessing hypertrophic cardiomyopathy in a boy with Rasopathy. 3D printing may supplement conventional imaging including echocardiography and MRI in the evaluation of hypertrophic cardiomyopathy.
June 25, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28647748/single-level-anterior-cervical-corpectomy-and-fusion-using-a-new-3d-printed-anatomy-adaptive-titanium-mesh-cage-for-treatment-of-cervical-spondylotic-myelopathy-and-ossification-of-the-posterior-longitudinal-ligament-a-retrospective-case-series-study
#16
Teng Lu, Chao Liu, Baohui Yang, Jiantao Liu, Feng Zhang, Dong Wang, Haopeng Li, Xijing He
BACKGROUND The aim of this study was to evaluate the clinical and radiological outcomes of the use of a new 3D-printed anatomy-adaptive titanium mesh cage (AA-TMC) for single-level anterior cervical corpectomy and fusion (ACCF) in patients with cervical spondylotic myelopathy (CSM) and ossification of the posterior longitudinal ligament (OPLL). MATERIAL AND METHODS We retrospectively reviewed the records of 15 consecutive patients who underwent ACCF surgeries with AA-TMC implantation. The Japanese Orthopedic Association (JOA) scoring system, a visual analogue scale (VAS), the mean intervertebral height (MIBH) of the surgical segments, and the surgical segmental angle (SSA) were recorded preoperatively, immediately after surgery and at the final follow-up visit...
June 25, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28647340/a-simulator-for-training-in-endovascular-aneurysm-repair-the-use-of-three-dimensional-printers
#17
I O Torres, N De Luccia
OBJECTIVES: To develop an endovascular aneurysm repair (EVAR) simulation system using three dimensional (3D) printed aneurysms, and to evaluate the impact of patient specific training prior to EVAR on the surgical performance of vascular surgery residents in a university hospital in Brazil. METHODS: This was a prospective, controlled, single centre study. During 2015, the aneurysms of patients undergoing elective EVAR at São Paulo University Medical School were 3D printed and used in training sessions with vascular surgery residents...
June 21, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28646444/engineering-3d-models-of-tumors-and-bone-to-understand-tumor-induced-bone-disease-and-improve-treatments
#18
REVIEW
Kristin A Kwakwa, Joseph P Vanderburgh, Scott A Guelcher, Julie A Sterling
PURPOSE OF REVIEW: Bone is a structurally unique microenvironment that presents many challenges for the development of 3D models for studying bone physiology and diseases, including cancer. As researchers continue to investigate the interactions within the bone microenvironment, the development of 3D models of bone has become critical. RECENT FINDINGS: 3D models have been developed that replicate some properties of bone, but have not fully reproduced the complex structural and cellular composition of the bone microenvironment...
June 23, 2017: Current Osteoporosis Reports
https://www.readbyqxmd.com/read/28645662/development-of-a-3d-printable-maxillofacial-silicone-part-ii-optimization-of-moderator-and-thixotropic-agent
#19
Swati K Jindal, Martyn Sherriff, Mark G Waters, James E Smay, Trevor J Coward
STATEMENT OF PROBLEM: Conventionally, maxillofacial prostheses are fabricated by hand carving the missing anatomic defect in wax and creating a mold into which pigmented silicone elastomer is placed. Digital technologies such as computer numerical control milling and 3-dimensional (3D) printing have been used to prepare molds, directly or indirectly, into which a biocompatible pigmented silicone elastomer can be placed. PURPOSE: The purpose of this in vitro study was to develop a silicone elastomer that could be 3D printed directly without a mold to create facial or body prostheses by varying its composition...
June 20, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28643930/moving-towards-precision-orthodontics-an-evolving-paradigm-shift-in-the-planning-and-delivery-of-customized-orthodontic-therapy
#20
REVIEW
A H Jheon, S Oberoi, R C Solem, S Kapila
Advances in precision medicine portend similar progress in orthodontics and will be increasingly harnessed to achieve customized treatment approaches and enhance treatment efficiencies. Our goal is to provide a background on emerging advances in computer technologies and biomedicine and highlight their current and likely future applications to precision orthodontics. A review of orthodontically relevant technologies and advances in pertinent biological research was undertaken. Innovations in computer hardware and software, and 3D imaging technologies offer the ability for customized treatment and biomechanical planning that will be more fully realized within the next few decades...
June 2017: Orthodontics & Craniofacial Research
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