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https://www.readbyqxmd.com/read/29235838/hydrogel-with-ultra-fast-self-healing-property-both-in-air-and-underwater
#1
Weipeng Chen, Dezhao Hao, Wanjun Hao, Xinglin Guo, Lei Jiang
Self-healing hydrogels have a great potential utilization in 3D printing, soft robotics, and tissue engineering, due to the ability to expand the useful lifespan. There has been a large number of successful strategies in developing hydrogels which exhibit rapid and autonomous recovery. However, a gel with an excellent self-healing performance within several seconds is still an enormous challenge. Here, an ultra-fast self-healing hydrogel based on a PVA/agarose double network is presented. The gel utilizing dynamic borate bond exhibits 100% cure in strength and elongation after healing for 10 seconds in air, and this hydrogel shows an excellent self-healing property underwater as well...
December 13, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29235445/direct-three-dimensional-printing-of-polymeric-scaffolds-with-nanofibrous-topography
#2
Aruna Prasopthum, Kevin Shakesheff, Jing Yang
Three-dimensional (3D) printing is a powerful manufacturing tool for making 3D structures with well-defined architectures for a wide range of applications. The field of tissue engineering has also adopted this technology to fabricate scaffolds for tissue regeneration. The ability to control architecture of scaffolds, e.g. matching anatomical shapes and having defined pore size, has since been improved significantly. However, the material surface of these scaffolds is smooth and does not resemble that found in natural extracellular matrix (ECM), in particular, the nanofibrous morphology of collagen...
December 13, 2017: Biofabrication
https://www.readbyqxmd.com/read/29234864/3d-printing-lunate-prosthesis-for-stage-iiic-kienb%C3%A3-ck-s-disease-a-case-report
#3
Mei-Ming Xie, Kang-Lai Tang, Chen-Song Yuan
Stage IIIc Kienböck's disease is a clinical challenge to treat collapse of the lunate bone. A new reconstructive surgery was described in one patient using 3D printing lunate prosthesis. The prosthesis shape was designed by tomographic image processing and segmentation using technology compared with the intact side matched by mirror symmetry and 3D post-processing technologies. The patient recovered nearly full range of motion of the wrist after 12 months. The visual analog scale scores and Cooney scores were 2 points and 91 points...
December 12, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29234768/3d-printed-seed-planter-and-well-array-for-high-throughput-seed-germination-screening
#4
Hui Hui Chai, Yao Lu, Can Fang, Ya Dan Li, Yue Jun Kang, Chang Ming Li, Ling Yu
Seed germination is an important means of evaluating seed quality. In the present study, a well array for a seed germination experiment was designed and fabricated by 3D printing for the first time. Each hollow cone-shaped well can hold one seed, which not only prevented the seed from falling out of the well but also ensured that part of the seed was fully exposed to the sublayer of wet filter paper, allowing it to receive water for germination. Coupled with a 3D-printed seed planter, single seeds can be quickly placed into arrayed wells...
December 13, 2017: Integrative Biology: Quantitative Biosciences From Nano to Macro
https://www.readbyqxmd.com/read/29234219/concept-and-design-of-a-3d-printed-support-to-assist-hand-scanning-for-the-realization-of-customized-orthosis
#5
Gabriele Baronio, Paola Volonghi, Alberto Signoroni
In the rehabilitation field, the use of additive manufacturing techniques to realize customized orthoses is increasingly widespread. Obtaining a 3D model for the 3D printing phase can be done following different methodologies. We consider the creation of personalized upper limb orthoses, also including fingers, starting from the acquisition of the hand geometry through accurate 3D scanning. However, hand scanning procedure presents differences between healthy subjects and patients affected by pathologies that compromise upper limb functionality...
2017: Applied Bionics and Biomechanics
https://www.readbyqxmd.com/read/29233510/patient-specific-puzzle-implant-preformed-with-3d-printed-rapid-prototype-model-for-combined-orbital-floor-and-medial-wall-fracture
#6
Young Chul Kim, Kyung Hyun Min, Jong Woo Choi, Kyung S Koh, Tae Suk Oh, Woo Shik Jeong
BACKGROUND: The management of combined orbital floor and medial wall fractures involving the inferomedial strut is challenging due to absence of stable cornerstone. In this article, we proposed surgical strategies using customized 3D puzzle implant preformed with Rapid Prototype (RP) skull model. METHODS: Retrospective review was done in 28 patients diagnosed with combined orbital floor and medial wall fracture. Using preoperative CT scans, original and mirror-imaged RP skull models for each patient were prepared and sterilized...
November 29, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29233449/a-pilot-study-assessing-the-value-of-3d-printed-molecular-modelling-tools-for-pharmacy-student-education
#7
Susan Hall, Gary Grant, Devinder Arora, Abdullah Karaksha, Amelia McFarland, Anna Lohning, Shailendra Anoopkumar-Dukie
BACKGROUND AND PURPOSE: Medicinal chemistry and pharmacology are difficult topics to both teach and learn given the complex nature of drug mechanisms and drug-receptor interactions. This highlights the need for innovative teaching methods to deliver this information to students. One such method is through three-dimensional (3D) printing of enzymes and ligands in the teaching of molecular modelling concepts relating to drug-receptor and enzyme interactions be ligands. This type of printing has been shown to be beneficial in several educational settings; however, to our knowledge, its effectiveness in pharmacy, medicinal chemistry and pharmacology learning and teaching is largely unknown...
July 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29231703/investigating-the-effect-of-column-geometry-on-separation-efficiency-using-3d-printed-liquid-chromatographic-columns-containing-polymer-monolithic-phases
#8
Vipul Gupta, Stephen Beirne, Pavel N Nesterenko, Brett Paull
Effect of column geometry on the liquid chromatographic separations using 3D printed liquid chromatographic columns with in-column polymerised monoliths has been studied. Three different liquid chromatographic columns were designed and 3D printed in titanium as 2D serpentine, 3D spiral, and 3D serpentine columns, of equal length and I.D. Successful in-column thermal polymerisation of mechanically stable poly(BuMA-co-EDMA) monoliths was achieved within each design without any significant structural differences between each phase...
December 12, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29227492/impact-of-complex-surfaces-on-biomicrorheological-measurements-using-optical-tweezers
#9
Shu Zhang, Lachlan J Gibson, Alexander B Stilgoe, Timo A Nieminen, Halina Rubinsztein-Dunlop
The characterisation of physical properties in biologically relevant processes and the development of novel microfluidic devices for this purpose are experiencing a great resurgence at present. In many of measurements of this type where a probe in a fluid is used, the strong influence of the boundaries of the volume used is a serious problem. In these geometries the proximity of a probe to a wall can severely influence the measurement. However, although much knowledge has been gained about flat walls, to date, the effect of non-planar surfaces at microscopic scale on rotational motion of micro-objects has not been studied...
December 11, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/29227110/itraq-quantitative-proteomic-profiling-and-maldi-msi-of-colon-cancer-spheroids-treated-with-combination-chemotherapies-in-a-3d-printed-fluidic-device
#10
Gabriel J LaBonia, Katelyn R Ludwig, C Bruce Mousseau, Amanda B Hummon
For a patient with metastatic colorectal cancer there are limited clinical options aside from chemotherapy. Unfortunately, the development of new chemotherapeutics is a long and costly process. New methods are needed to identify promising drug candidates earlier in the drug development process. Most chemotherapies are administered to patients in combinations. Here, an in vitro platform is used to assess the penetration and metabolism of combination chemotherapies in three-dimensional colon cancer cell cultures, or spheroids...
December 11, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29226501/drop-on-drop-multimaterial-3d-bioprinting-realized-by-peroxidase-mediated-cross-linking
#11
Shinji Sakai, Kohei Ueda, Enkhtuul Gantumur, Masahito Taya, Makoto Nakamura
A cytocompatible inkjet bioprinting approach that enables the use of a variety of bioinks to produce hydrogels with a wide range of characteristics is developed. Stabilization of bioinks is caused by horseradish peroxidase (HRP)-catalyzed cross-linking consuming hydrogen peroxide (H2 O2 ). 3D cell-laden hydrogels are fabricated by the sequential dropping of a bioink containing polymer(s) cross-linkable through the enzymatic reaction and H2 O2 onto droplets of another bioink containing the polymer, HRP, and cells...
December 11, 2017: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/29226262/topology-optimization-aided-structural-design-interpretation-computational-aspects-and-3d-printing
#12
Georgios Kazakis, Ioannis Kanellopoulos, Stefanos Sotiropoulos, Nikos D Lagaros
Construction industry has a major impact on the environment that we spend most of our life. Therefore, it is important that the outcome of architectural intuition performs well and complies with the design requirements. Architects usually describe as "optimal design" their choice among a rather limited set of design alternatives, dictated by their experience and intuition. However, modern design of structures requires accounting for a great number of criteria derived from multiple disciplines, often of conflicting nature...
October 2017: Heliyon
https://www.readbyqxmd.com/read/29225219/layer-caused-an-anisotropic-terahertz-response-of-a-3d-printed-simulative-shale-core
#13
Xinyang Miao, Limei Guan, Rima Bao, Yizhang Li, Honglei Zhan, Kun Zhao, Xiaodong Wang, Fan Xu
Energy demands have motivated the development of shale formations as significant unconventional reservoirs. The anisotropy of shales plays a significant role in both the mechanical behavior and engineering activities. Alternating layers presented in shales affect the propagation of waves, causing anisotropy at various frequencies. Simplifying the complicated interior structures of shales is conducive to characterize the anisotropic properties. Therefore, simulative shale core samples were designed and fabricated using additive manufacturing processes, and layer-caused dielectric anisotropy was investigated by terahertz (THz) time-domain spectroscopy...
2017: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
https://www.readbyqxmd.com/read/29224416/utilising-three-dimensional-printing-techniques-when-providing-unique-assistive-devices-a-case-report
#14
Sarah Jane Day, Shaun Patrick Riley
BACKGROUND: The evolution of three-dimensional printing into prosthetics has opened conversations about the availability and cost of prostheses. This report will discuss how a prosthetic team incorporated additive manufacture techniques into the treatment of a patient with a partial hand amputation to create and test a unique assistive device which he could use to hold his French horn. Case description and methods: Using a process of shape capture, photogrammetry, computer-aided design and finite element analysis, a suitable assistive device was designed and tested...
December 1, 2017: Prosthetics and Orthotics International
https://www.readbyqxmd.com/read/29224259/-expert-consensus-of-precise-diagnosis-and-treatment-for-pancreatic-head-cancer-using-three-dimensional-visualization-technology
#15
(no author information available yet)
Three-dimensional (3D) visualization technology in pancreatic head cancers could offer decision-making support to preoperative diagnosis, resectability assessment and individualized surgical planning. In addition, the pancreas 3D printing helps to realize the leapfrog development from 3D images to 3D physical models and provides better guidance of the precise surgery of complicated cancers of the pancreatic head. In order to standardize the application of 3D visualization and 3D printing technology in the diagnosis and treatment of pancreatic head cancer, Chinese experts in relevant fields were organized by four committees to formulate this expert consensus...
December 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/29223704/decellularized-heart-ecm-hydrogel-using-supercritical-carbon-dioxide-for-improved-angiogenesis
#16
Yoojin Seo, Youngmee Jung, Soo Hyun Kim
Initial angiogenesis within the first 3 days is critical for healing ischemic diseases such as myocardial infarction. Recently, decellularized extracellular matrix (dECM) has been reported to provide tissue-derived ECM components and can be used as a scaffold for cell delivery for angiogenesis in tissue engineering. Decellularization by various detergents such as sodium dodecyl sulfate (SDS) and triton X-100 can remove the cell nuclei in tissue organs. However, this leads to ECM structure denaturation, decreased presence of various ECM proteins and cytokines, and loss of mechanical properties...
December 6, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29223522/custom-made-titanium-3d-printed-interbody-cages-for-treatment-of-osteoporotic-fracture-related-spinal-deformity
#17
Timothy Siu, Jeffrey M Rogers, Kainu Lin, Robert Thompson, Mark Owbridge
BACKGROUND: Advances in minimally invasive interbody fusion have greatly enhanced surgeons' capability to correct adult spinal deformity with reduced morbidity. However, the feasibility of such approaches is limited in patients with previous osteoporotic fractures as the resultant vertebral deformity renders the endplate geometry incongruous with conventional interbody implants. Current 3D printing technology offers a novel solution by fabricating custom-made implants tailored to individual anatomy...
December 6, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29223036/study-on-temperature-and-near-infrared-driving-characteristics-of-hydrogel-actuator-fabricated-via-molding-and-3d-printing
#18
Qian Zhao, Yunhong Liang, Lei Ren, Feng Qiu, Zhihui Zhang, Luquan Ren
A hydrogel material system which was fit for molding and 3D printing was developed to fabricate bilayer hydrogel actuators with controllable temperature and near infrared laser responses. Polymerization on interface boundary of layered structure enhanced the bonding strength of hydrogel actuators. By utilizing anisotropic of microstructure along with thickness direction, bilayer hydrogel actuators fabricated via molding realized intelligent bending/shrinking responses, which guided the preparation of hydrogel ink for 3D printing...
December 2, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29222837/low-melt-bioactive-glass-reinforced-3d-printing-akermanite-porous-cages-with-highly-improved-mechanical-properties-for-lumbar-spinal-fusion
#19
Xiurong Ke, Lei Zhang, Xianyan Yang, Juncheng Wang, Chen Zhuang, Zhouwen Jin, An Liu, Tengfei Zhao, Sanzhong Xu, Changyou Gao, Zhongru Gou, Guojing Yang
Although great strides have been made in medical technology, low back/neck pain and intervertebral disc degeneration initiated from disc degenerative disease remains a clinical challenge. Within the field of regenerative medicine therapy, we have sought to improve the biomechanical transformation of spinal fusion procedures conducted using biodegradable porous implants. Specifically, we have focused on developing mechanically strong bioceramic cages for spinal fusion and functional recovery. Herein we fabricated the akermanite (AKE) ceramic-based porous cages using low-melting bioactive glass (BG) and 3D printing technology...
December 9, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/29222738/ct-based-3d-printing-is-superior-to-transesophageal-echocardiography-for-pre-procedure-planning-in-left-atrial-appendage-device-closure
#20
Edinrin Obasare, Sumeet K Mainigi, D Lynn Morris, Leandro Slipczuk, Igor Goykhman, Evan Friend, Mary Rodriguez Ziccardi, Gregg S Pressman
Accurate assessment of the left atrial appendage (LAA) is important for pre-procedure planning when utilizing device closure for stroke reduction. Sizing is traditionally done with transesophageal echocardiography (TEE) but this is not always precise. Three-dimensional (3D) printing of the LAA may be more accurate. 24 patients underwent Watchman device (WD) implantation (71 ± 11 years, 42% female). All had complete 2-dimensional TEE. Fourteen also had cardiac computed tomography (CCT) with 3D printing to produce a latex model of the LAA for pre-procedure planning...
December 8, 2017: International Journal of Cardiovascular Imaging
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