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Exercise and memory

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https://www.readbyqxmd.com/read/28108329/exercise-increases-mitochondrial-complex-i-activity-and-drp1-expression-in-the-brains-of-aged-mice
#1
Aaron M Gusdon, Jason Callio, Giovanna DiStefano, Robert M O'Doherty, Bret H Goodpaster, Paul M Coen, Charleen T Chu
Exercise is known to have numerous beneficial effects. Recent studies indicate that exercise improves mitochondrial energetics not only in skeletal muscle but also in other tissues. While exercise elicits positive effects on memory, neurogenesis, and synaptic plasticity, the effects of exercise on brain mitochondrial energetics remain relatively unknown. Herein, we studied the effects of exercise training in old and young mice on brain mitochondrial energetics, in comparison to known effects on peripheral tissues that utilize fatty acid oxidation...
January 17, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28108255/regular-exercise-promotes-memory-function-and-enhances-hippocampal-neuroplasticity-in-experimental-autoimmune-encephalomyelitis-mice
#2
Tae-Woon Kim, Yun-Hee Sung
Multiple sclerosis (MS) is a progressive condition affecting the central nervous system (CNS), and is characterized by the development of demyelinated lesions and plaques in the brain and spinal cord. Exercise is beneficial against dementia in elderly patients, so we investigated the effects of exercise on memory in relation to hippocampal demyelination and neuroplasticity in a mouse model of MS (experimental autoimmune encephalomyelitis [EAE]). Mice were randomly divided into three groups: Sham, EAE, and EAE and exercise (EAE+EX)...
January 17, 2017: Neuroscience
https://www.readbyqxmd.com/read/28078614/resistance-exercise-reduces-seizure-occurrence-attenuates-memory-deficits-and-restores-bdnf-signaling-in-rats-with-chronic-epilepsy
#3
Alexandre Aparecido de Almeida, Sérgio Gomes da Silva, Glauber Menezes Lopim, Diego Vannucci Campos, Jansen Fernandes, Francisco Romero Cabral, Ricardo Mario Arida
Epilepsy is a disease characterized by recurrent, unprovoked seizures. Cognitive impairment is an important comorbidity of chronic epilepsy. Human and animal model studies of epilepsy have shown that aerobic exercise induces beneficial structural and functional changes and reduces the number of seizures. However, little is yet understood about the effects of resistance exercise on epilepsy. We evaluated the effects of a resistance exercise program on the number of seizures, long-term memory and expression/activation of signaling proteins in rats with epilepsy...
January 11, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28071936/concussion-baseline-testing-preexisting-factors-symptoms-and-neurocognitive-performance
#4
Eric Hall, Jordan Cottle, Caroline Ketcham, Kirtida Patel, Kenneth P Barnes
CONTEXT:  Neurocognitive test scores are often considered an important aspect of concussion management. To best use these data, clinicians must understand potential factors that may influence baseline performance on these tests. OBJECTIVE:  To determine preexisting factors that may influence performance on the Immediate Post-Concussion Assessment and Cognitive Test (ImPACT). DESIGN:  Cross-sectional study. SETTING:  Research laboratory...
January 10, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28067736/alzheimer-s-disease-and-exercise-a-literature-review
#5
Shane P Cass
Alzheimer's disease (AD) is a progressive neurodegenerative disease that impairs memory and cognitive judgment. It is the leading cause of dementia in late adult life and is associated with a significant social burden and increased morbidity and mortality in the elderly. Because of mixed effectiveness of medications, exercise has been considered as a treatment for pre-clinical AD, late stage AD, and as a prevention strategy. Exercise appears to improve brain blood flow, increase hippocampal volume, and improve neurogenesis...
January 2017: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/28067610/the-efficacy-of-a-computer-assisted-cognitive-rehabilitation-program-for-patients-with-mild-cognitive-deficits-a-pilot-study
#6
William E Mansbach, Ryan A Mace, Kristen M Clark
: Background/Study Context: Whereas computer-assisted cognitive rehabilitation (CR) programs show promise as tools for improving cognition in certain populations, there is not a consensus regarding their efficacy. This study focuses on restorative CR, a treatment designed to improve cognitive functioning affected by progressive brain changes due to disease or aging, through computer-assisted cognitive exercises. The purpose of this study was to investigate the efficacy of a computer-assisted restorative CR intervention for improving cognitive functioning in older rehabilitation patients with relatively mild cognitive deficits...
January 2017: Experimental Aging Research
https://www.readbyqxmd.com/read/28065988/exercise-prescription-perceptions-and-physical-activity-habits-in-chiropractic-students-at-cmcc
#7
Scott Howitt, Eric Ethridge, Eric Nelson, Mike Gotuaco, Louis Demello
BACKGROUND: Health care practitioner's physical activity (PA) habits are associated with their likelihood to recommend PA to their patients. The intent of this project is to better understand the Canadian Memorial Chiropractic College (CMCC) students' perceptions and practices of PA and exercise prescription as this may predict exercise counselling they will provide to future patients. METHODS: A 27-item survey was distributed to Canadian Memorial Chiropractic College (CMCC) students (N = 744)...
December 2016: Journal of the Canadian Chiropractic Association
https://www.readbyqxmd.com/read/28064173/interventions-to-prevent-or-reduce-the-level-of-frailty-in-community-dwelling-older-adults-a-scoping-review-of-the-literature-and-international-policies
#8
REVIEW
Martine T E Puts, Samar Toubasi, Melissa K Andrew, Maureen C Ashe, Jenny Ploeg, Esther Atkinson, Ana Patricia Ayala, Angelique Roy, Miriam Rodríguez Monforte, Howard Bergman, Kathy McGilton
BACKGROUND: frailty impacts older adults' ability to recover from an acute illness, injuries and other stresses. Currently, a systematic synthesis of available interventions to prevent or reduce frailty does not exist. Therefore, we conducted a scoping review of interventions and international policies designed to prevent or reduce the level of frailty in community-dwelling older adults. METHODS AND ANALYSIS: we conducted a scoping review using the framework of Arksey and O'Malley. We systematically searched articles and grey literature to identify interventions and policies that aimed to prevent or reduce the level of frailty...
January 6, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28058207/memory-loss-five-new-things
#9
Ferenc Deak, Nidhi Kapoor, Calin Prodan, Linda A Hershey
PURPOSE OF REVIEW: Memory loss can be due to a wide variety of causes. We provide new information about the biology of common genetic and acquired causes of memory loss in older adults. RECENT FINDINGS: New data are available about the genetics of Alzheimer disease (AD), dementia with Lewy bodies (DLB), and frontotemporal dementia. Amyloid PET, FDG-PET, and MRI have improved our understanding of how mild cognitive impairment evolves to AD. Several studies have shown links between concussion and chronic traumatic encephalopathy...
December 2016: Neurology. Clinical Practice
https://www.readbyqxmd.com/read/28056892/correlations-between-physical-activity-and-neurocognitive-domain-functions-in-patients-with-schizophrenia-a-cross-sectional-study
#10
Yusuke Kurebayashi, Junichi Otaki
BACKGROUND: Neurocognitive dysfunction is a critical target symptom of schizophrenia treatment. A positive correlation between physical activity level and neurocognitive function has been reported in healthy individuals, but it is unclear whether such a correlation exists in patients with schizophrenia and whether the relationship is different according to inpatients or outpatients. This study aimed to examine the differences in the correlations between physical activity and multiple neurocognitive domains in inpatients and outpatients with schizophrenia and obtain suggestions for further study to facilitate this field...
January 5, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28056410/role-of-bdnf-val66met-polymorphism-in-modulating-exercised-induced-emotional-memories
#11
Dharani Keyan, Richard A Bryant
Brief physical exercise enhances memories for neutral events, and modulates fear learning in animals. Exercise-induced arousal induces the release of brain-derived neurotrophic factor (BDNF), which may moderate memory-enhancing effects. This study investigated the effect of exercise, and the extent to which the BDNF val66met polymorphism (which limits BDNF activity-dependent secretion) influenced emotional memories. Sixty-two healthy participants were randomly assigned to either 10min of intense exercise (n=31) or slow walking (control condition; n=31), and then immediately viewed positive and negative images...
December 21, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28050361/effects-of-swimming-exercise-on-learning-and-memory-in-the-kainate-lesion-model-of-temporal-lobe-epilepsy
#12
Vasavi Rakesh Gorantla, Sudhakar Pemminati, Vernon Bond, Dewey G Meyers, Richard Mark Millis
INTRODUCTION: An aerobic exercise (Ex) augments neurogenesis and may ameliorate learning and memory deficits in the rat Kainic Acid (KA) model of temporal lobe epilepsy in the short-term but whether it reverses learning and memory deficits after a substantial period of delay remains unclear. AIM: This study tests the hypothesis that aerobic Ex attenuates the learning and memory deficits associated with kainate seizures in the long-term. MATERIALS AND METHODS: A total of 60 rats were subjected to chemical lesioning using KA and to an Ex intervention consisting of a 30 days period of daily swimming for 15 min, immediately after KA lesioning (immediate exposure) or after a 60 days period of normal activity (delayed exposure)...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28039090/effects-of-previous-physical-exercise-to-chronic-stress-on-long-term-aversive-memory-and-oxidative-stress-in-amygdala-and-hippocampus-of-rats
#13
Tiago Marcon Dos Santos, Janaína Kolling, Cassiana Siebert, Helena Biasibetti, Carolina Gessinger Bertó, Lucas Kich Grun, Carla Dalmaz, Florencia María Barbé-Tuana, Angela T S Wyse
Since stressful situations are considered risk factors for the development of depression and there are few studies evaluating prevention therapies for this disease, in the present study we evaluated the effect of previous physical exercise in animals subjected to chronic variable stress (CVS), an animal model of depression, on behavior tasks. We also investigated some parameters of oxidative stress and Na(+), K(+)-ATPase activity, immunocontent and gene expression of alpha subunits in amygdala and hippocampus of rats...
December 27, 2016: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/28018192/differences-in-resting-state-functional-connectivity-between-young-adult-endurance-athletes-and-healthy-controls
#14
David A Raichlen, Pradyumna K Bharadwaj, Megan C Fitzhugh, Kari A Haws, Gabrielle-Ann Torre, Theodore P Trouard, Gene E Alexander
Expertise and training in fine motor skills has been associated with changes in brain structure, function, and connectivity. Fewer studies have explored the neural effects of athletic activities that do not seem to rely on precise fine motor control (e.g., distance running). Here, we compared resting-state functional connectivity in a sample of adult male collegiate distance runners (n = 11; age = 21.3 ± 2.5) and a group of healthy age-matched non-athlete male controls (n = 11; age = 20.6 ± 1.1), to test the hypothesis that expertise in sustained aerobic motor behaviors affects resting state functional connectivity in young adults...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27997992/acute-moderate-exercise-improves-mnemonic-discrimination-in-young-adults
#15
Kazuya Suwabe, Kazuki Hyodo, Kyeongho Byun, Genta Ochi, Michael A Yassa, Hideaki Soya
Increasing evidence suggests that regular moderate exercise increases neurogenesis in the dentate gyrus (DG) of the hippocampus and improves memory functions in both humans and animals. The DG is known to play a role in pattern separation, which is the ability to discriminate among similar experiences, a fundamental component of episodic memory. While long-term voluntary exercise improves pattern separation, there is little evidence of alterations in DG function after an acute exercise session. Our previous studies showing acute moderate exercise-enhanced DG activation in rats, and acute moderate exercise-enhanced prefrontal activation and executive function in humans, led us to postulate that acute moderate exercise may also activate the hippocampus, including more specifically the DG, thus improving pattern separation...
December 20, 2016: Hippocampus
https://www.readbyqxmd.com/read/27995604/exercise-therapy-for-chronic-fatigue-syndrome
#16
REVIEW
Lillebeth Larun, Kjetil G Brurberg, Jan Odgaard-Jensen, Jonathan R Price
BACKGROUND: Chronic fatigue syndrome (CFS) is characterised by persistent, medically unexplained fatigue, as well as symptoms such as musculoskeletal pain, sleep disturbance, headaches and impaired concentration and short-term memory. CFS presents as a common, debilitating and serious health problem. Treatment may include physical interventions, such as exercise therapy, which was last reviewed in 2004. OBJECTIVES: The objective of this review was to determine the effects of exercise therapy (ET) for patients with CFS as compared with any other intervention or control...
December 20, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27984020/physical-exercise-reverses-spatial-memory-deficit-and-induces-hippocampal-astrocyte-plasticity-in-diabetic-rats
#17
Priscylla Nunes de Senna, Pamela Brambilla Bagatini, Fabiana Galland, Larissa Bobermin, Patrícia Severo do Nascimento, Patrícia Nardin, Ana Carolina Tramontina, Carlos Alberto Gonçalves, Matilde Achaval, Léder Leal Xavier
Physical exercise can induce brain plasticity and reduce the cognitive decline observed in type 1 diabetes mellitus (T1DM). We investigated the effects of physical exercise to prevent or reverse spatial memory deficits produced by diabetes and some biochemical and immunohistochemical changes in hippocampal astrocytes of T1DM model. In this study, 56 male Wistar rats were divided in four groups: trained control (TC), non-trained control (NTC), trained diabetic (TD) and non-trained diabetic (NTD). 27 days after streptozotocin-induced (STZ) diabetes, the exercise groups were submitted to 5 weeks of aerobic exercise...
January 15, 2017: Brain Research
https://www.readbyqxmd.com/read/27977432/the-effects-of-early-exercise-on-motor-sense-and-memory-recovery-in-rats-with-stroke
#18
Liqiang Yang, Jie Zhang, Yihao Deng, Pengyue Zhang
OBJECTIVE: Exercise is an effective, inexpensive, home-based, and accessible intervention strategy for stroke treatment, and early exercise after stroke has attracted a great deal of attention in recent years. However, the effects of early exercise on comprehensive functional recovery remain poorly understood. The present study investigated the effect of early exercise on motor, sense, balance, and spatial memory recovery. DESIGN: Adult Sprague-Dawley rats were subjected to unilateral middle cerebral artery occlusion (MCAO) and were randomly divided into early exercise group (EE), non-exercise group (NE), and sham group...
December 9, 2016: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/27976973/elevated-rates-of-memory-impairment-in-military-service-members-and-veterans-with-posttraumatic-stress-disorder
#19
Nikki H Stricker, Sara M Lippa, Deborah L Green, Susan M McGlynn, Laura J Grande, William P Milberg, Regina E McGlinchey
INTRODUCTION: Studies investigating the neurocognitive effects of posttraumatic stress disorder (PTSD) routinely find "deficits" in various cognitive domains. However, the rate of cognitive impairment in individuals with PTSD remains unclear, as studies have focused on null hypothesis testing (NHT) and inferring patterns of impairment rather than empirically determining the rate of cognitive impairment in this sample. METHOD: This study examined rates of cognitive impairment using a domain-specific approach in non-treatment-seeking Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn service members and veterans with (n = 92) and without (n = 79) PTSD and without substance abuse/dependence who passed a performance validity measure and were matched on age, education, estimated IQ, and ethnicity...
December 15, 2016: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/27956050/the-exercise-glucocorticoid-paradox-how-exercise-is-beneficial-to-cognition-mood-and-the-brain-while-increasing-glucocorticoid-levels
#20
REVIEW
Chong Chen, Shin Nakagawa, Yan An, Koki Ito, Yuji Kitaichi, Ichiro Kusumi
Exercise is known to have beneficial effects on cognition, mood, and the brain. However, exercise also activates the hypothalamic-pituitary-adrenal axis and increases levels of the glucocorticoid cortisol (CORT). CORT, also known as the "stress hormone," is considered a mediator between chronic stress and depression and to link various cognitive deficits. Here, we review the evidence that shows that while both chronic stress and exercise elevate basal CORT levels leading to increased secretion of CORT, the former is detrimental to cognition/memory, mood/stress coping, and brain plasticity, while the latter is beneficial...
January 2017: Frontiers in Neuroendocrinology
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