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Exercise and memory

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https://www.readbyqxmd.com/read/29447133/computerised-training-improves-cognitive-performance-in-chronic-pain-a-participant-blinded-randomised-active-controlled-trial-with-remote-supervision
#1
Katharine S Baker, Nellie Georgiou-Karistianis, Amit Lampit, Michael Valenzuela, Stephen J Gibson, Melita J Giummarra
Chronic pain is associated with reduced efficiency of cognitive performance, and few studies have investigated methods of remediation. We trialled a computerised cognitive training protocol to determine whether it could attenuate cognitive difficulties in a chronic pain sample. Thirty-nine adults with chronic pain (mean age = 43.3, 61.5% females) were randomised to an 8-week online course (3 sessions/week from home) of game-like cognitive training exercises, or an active control involving watching documentary videos...
January 11, 2018: Pain
https://www.readbyqxmd.com/read/29446452/development-of-children-s-use-of-external-reminders-for-hard-to-remember-intentions
#2
Jonathan Redshaw, Johanna Vandersee, Adam Bulley, Sam J Gilbert
This study explored under what conditions young children would set reminders to aid their memory for delayed intentions. A computerized task requiring participants to carry out delayed intentions under varying levels of cognitive load was presented to 63 children (aged between 6.9 and 13.0 years old). Children of all ages demonstrated metacognitive predictions of their performance that were congruent with task difficulty. Only older children, however, set more reminders when they expected their future memory performance to be poorer...
February 15, 2018: Child Development
https://www.readbyqxmd.com/read/29444740/associations-between-modifiable-lifestyle-factors-and-multidimensional-cognitive-health-among-community-dwelling-old-adults-stratified-by-educational-level
#3
Manqiong Yuan, Jia Chen, Yaofeng Han, Xingliang Wei, Zirong Ye, Liangwen Zhang, Y Alicia Hong, Ya Fang
BACKGROUND: Cognition is multidimensional, and each domain plays a unique and crucial part in successful daily life engagement. However, less attention has been paid to multi-domain cognitive health for the elderly, and the role of lifestyle factors in each domain remains unclear. METHODS: We conducted a cross-sectional study of 3,230 older adults aged 60+ years in Xiamen, China, in 2016. The Montreal Cognitive Assessment (MoCA) was used to measure general cognition and six specific sub-domains...
February 15, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/29442554/neurogenesis-remembering-all-or-forgetting-some
#4
Shikha Jain Goodwin
Research over the last 20 years has begun to elucidate the importance of adult neurogenesis in cognition. Three studies recently asked what might be happening to memories formed before neurogenesis in the hippocampus (Akers et al. 2014; Epp et al. 2016; Kodali et al. 2016). These studies found conflicting results: running (which increases neurogenesis) induced forgetting in two studies, but there was no difference in memory retrieval after exercise in another. To reconcile these studies, one must understand the processes behind memory maintenance and recall, and consider context, species and other factors...
February 14, 2018: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29436629/cognitive-improvement-following-ischemia-reperfusion-injury-induced-by-voluntary-running%C3%A2-wheel-exercise-is-associated-with-lncmalat1%C3%A2-mediated-apoptosis-inhibition
#5
Jin-Lin Shang, Qing Cheng, Sheng-Jie Duan, Lu Li, Li-Ya Jia
Previous human and animal studies demonstrated that voluntary exercise may improve cognitive function and facilitate neuronal plasticity in ischemia/reperfusion (I/R) models. However, the possible underlying mechanisms remain to be elucidated. Metastasis‑associated lung adenocarcinoma transcript 1 (MALAT1), a long noncoding RNA (lncRNA), may be associated with the functions and dysfunctions of endothelial cells. The present study investigated whether spontaneous running‑wheel (RW) exercise‑induced MALAT1 expression changes may be associated with the cognitive improvement of mice following I/R injury...
February 12, 2018: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29431549/self-paced-cycling-improves-cognition-on-institutionalized-older-adults-without-known-cognitive-impairment-a-15-month-randomized-controlled-trial
#6
Silvia Varela, José M Cancela, Manuel Seijo-Martinez, Carlos Ayán
This study aimed at identifying the effects of self-paced cycling on the cognitive and functional status and fall risk on institutionalized older adults without cognitive impairment. Thirty-nine individuals were randomly assigned to an exercise (EG) or to a control (CG) group. The EG participants cycled at their self-selected intensity at least for 15 minutes daily during 15 months. The CG participants performed recreational activities. The Mini-Mental State Examination, Fuld Object Memory Evaluation, and Symbol Digit Modality Test were used for cognitive assessments...
February 12, 2018: Journal of Aging and Physical Activity
https://www.readbyqxmd.com/read/29430053/exercise-as-a-vital-sign-a-preliminary-pilot-study-in-a-chiropractic-setting
#7
Scott Howitt, Kyle Simpson, Darren Suderman, Andrew Mercer, Susan Rutherford, Christopher deGraauw
Background: The association between physical inactivity and non-communicable disease risk has been well documented in recent literature. An exercise vital sign (EVS) is a measure that can routinely capture vital information about a patient's physical activity behaviour. The objective of this study is to understand if (1) patient exercise minutes per week (EMPW) are being recorded by chiropractic interns, and (2) whether these patients are exceeding, meeting or falling short of the current recommendations provided by the Canadian Physical Activity Guidelines (CPAG)...
December 2017: Journal of the Canadian Chiropractic Association
https://www.readbyqxmd.com/read/29416879/establishing-research-priorities-relating-to-the-long-term-impact-of-tia-and-minor-stroke-through-stakeholder-centred-consensus
#8
Grace M Turner, Ruth Backman, Christel McMullan, Jonathan Mathers, Tom Marshall, Melanie Calvert
Plain English summary: What is the problem and why is this important? Mini-strokes are similar to full strokes, but symptoms last less than 24 h. Many people (up to 70%) have long-term problems after a mini-stroke, such as anxiety; depression; problems with brain functioning (like memory loss); and fatigue (feeling tired). However, the current healthcare pathway only focuses on preventing another stroke and care for other long-term problems is not routinely given. Without proper treatment, people with long-term problems after a mini-stroke could have worse quality of life and may find it difficult to return to work and their social activities...
2018: Research Involvement and Engagement
https://www.readbyqxmd.com/read/29408274/running-exercise-mitigates-the-negative-consequences-of-chronic-stress-on-dorsal-hippocampal-long-term-potentiation-in-male-mice
#9
Roxanne M Miller, David Marriott, Jacob Trotter, Tyler Hammond, Dane Lyman, Timothy Call, Bethany Walker, Nathanael Christensen, Deson Haynie, Zoie Badura, Morgan Homan, Jeffrey G Edwards
In the hippocampus, learning and memory are likely mediated by synaptic plasticity, known as long-term potentiation (LTP). While chronic intermittent stress is negatively correlated, and exercise positively correlated to LTP induction, we examined whether exercise could mitigate the negative consequences of stress on LTP when co-occurring with stress. Mice were divided into four groups: sedentary no stress, exercise no stress, exercise with stress, and sedentary with stress. Field electrophysiology performed on brain slices confirmed that stress alone significantly reduced dorsal CA1 hippocampal LTP and exercise alone increased LTP compared to controls...
February 9, 2018: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/29407247/effects-of-modality-and-repetition-in-a-continuous-recognition-memory-task-repetition-has-no-effect-on-auditory-recognition-memory
#10
Azlina Amir Kassim, Rehan Rehman, Jessica M Price
Previous research has shown that auditory recognition memory is poorer compared to visual and cross-modal (visual and auditory) recognition memory. The effect of repetition on memory has been robust in showing improved performance. It is not clear, however, how auditory recognition memory compares to visual and cross-modal recognition memory following repetition. Participants performed a recognition memory task, making old/new discriminations to new stimuli, stimuli repeated for the first time after 4-7 intervening items (R1), or repeated for the second time after 36-39 intervening items (R2)...
February 3, 2018: Acta Psychologica
https://www.readbyqxmd.com/read/29405944/experimental-effects-of-acute-exercise-on-episodic-memory-acquisition-decomposition-of-multi-trial-gains-and-losses
#11
Eveleen Sng, Emily Frith, Paul D Loprinzi
OBJECTIVE: Research demonstrates that acute exercise may enhance retention of multi-trial episodic memories. Previous work has examined the effects of exercise on the mean level of memory recall. However, no study has examined whether exercise can influence the acquisition of new items, which was the purpose of this experiment. METHODS: Using a randomized controlled trial design, participants (young adults; Mage=22yrs) completed either a high-intensity bout of treadmill exercise for 15-min (n=22) or sat (n=22) prior to completing a multi-trial episodic memory task...
March 15, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29382913/human-skeletal-muscle-possesses-an-epigenetic-memory-of-hypertrophy
#12
Robert A Seaborne, Juliette Strauss, Matthew Cocks, Sam Shepherd, Thomas D O'Brien, Ken A van Someren, Phillip G Bell, Christopher Murgatroyd, James P Morton, Claire E Stewart, Adam P Sharples
It is unknown if adult human skeletal muscle has an epigenetic memory of earlier encounters with growth. We report, for the first time in humans, genome-wide DNA methylation (850,000 CpGs) and gene expression analysis after muscle hypertrophy (loading), return of muscle mass to baseline (unloading), followed by later hypertrophy (reloading). We discovered increased frequency of hypomethylation across the genome after reloading (18,816 CpGs) versus earlier loading (9,153 CpG sites). We also identified AXIN1, GRIK2, CAMK4, TRAF1 as hypomethylated genes with enhanced expression after loading that maintained their hypomethylated status even during unloading where muscle mass returned to control levels, indicating a memory of these genes methylation signatures following earlier hypertrophy...
January 30, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29370673/arc-arg3-1-protein-expression-in-dorsal-hippocampal-ca1-a-candidate-event-as-a-biomarker-for-the-effects-of-exercise-on-chronic-stress-evoked-behavioral-abnormalities
#13
Yea-Hyun Leem, Hyukki Chang
PURPOSE: Chronic stress is a risk factor for behavioral deficits, including impaired memory processing and depression. Exercise is well known to have beneficial impacts on brain health. METHODS: Mice were forced to treadmill running (4-week) during chronic restraint stress (6h/21d), and then behavioral tests were conducted by Novel object recognition, forced swimming test: FST, sociality test: SI. Dissected brain was stained with anti-calbindin-d28k and anti-Arc antibodies...
December 31, 2017: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29370668/the-potential-role-of-exercise-in-chronic-stress-related-changes-in-ampa-receptor-phenotype-underlying-synaptic-plasticity
#14
Yea-Hyun Leem
PURPOSE: Chronic stress can cause disturbances in synaptic plasticity, such as longterm potentiation, along with behavioral defects including memory deficits. One major mechanism sustaining synaptic plasticity involves the dynamics and contents of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) in the central nervous system. In particular, chronic stress-induced disruption of AMPARs includes it abnormal expression, trafficking, and calcium conductance at glutamatergic synapses, which contributes to synaptic plasticity at excitatory synapses...
December 31, 2017: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29368393/resistance-exercise-and-episodic-memory-function-a%C3%A2-systematic-review
#15
REVIEW
Paul D Loprinzi, Emily Frith, Meghan K Edwards
OBJECTIVE: Emerging research demonstrates that aerobic-based physical activity is favourably associated with episodic memory function. Despite resistance exercises being associated with a multitude of health outcomes, independent of aerobic physical activity, less research has examined the effects of resistance exercise on episodic memory function. The purpose of this study was to conduct a systematic review to examine the extent to which resistance exercise may be associated with episodic memory function...
January 24, 2018: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/29368298/a-web-based-multidomain-lifestyle-intervention-with-connected-devices-for-older-adults-research-protocol-of-the-emind-pilot-randomized-controlled-trial
#16
Kristell Pothier, G Soriano, M Lussier, A Naudin, N Costa, S Guyonnet, A Piau, P J Ousset, F Nourhashemi, B Vellas, P de Souto Barreto
BACKGROUND: Multidomain interventions composed of nutritional counseling, exercise and cognitive trainings have shown encouraging results as effective preventive strategies delaying age-related declines. However, these interventions are time- and resource-consuming. The use of Information and Communication Technologies (ICT) might facilitate the translation from research into real-world practice and reach a massive number of people. AIM: This article describes the protocol of the eMIND study, a randomized controlled trial (RCT) using a web-based multidomain intervention for older adults...
January 24, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29360489/voluntary-exercise-impact-on-cognitive-impairments-in-sleep-deprived-intact-female-rats
#17
Mohammad Amin Rajizadeh, Khadijeh Esmaeilpour, Yaser Masomi-Ardakani, Mohammad Abbas Bejeshk, Mohammad Shabani, Nouzar Nakhaee, Mohammad Pour Ranjbar, Fatemeh Mohtashami Borzadaran, Vahid Sheibani
Sleep loss is a common problem in modern societies affecting different aspects of individuals' lives. Many studies have reported that sleep deprivation (SD) leads to impairments in various types of learning and memory. Physical exercise has been suggested to attenuate the cognitive impairments induced by sleep deprivation in male rats. Our previous studies have shown that forced exercise by treadmill improved learning and memory impairments following SD. The aim of the current study was to investigate the effects of voluntary exercise by running wheel on cognitive, motor and anxiety-like behavior functions of female rats following 72h SD...
January 19, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29358034/the-effects-of-a-school-based-exercise-program-on-neurophysiological-indices-of-working-memory-operations-in-adolescents
#18
Sebastian Ludyga, Markus Gerber, Keita Kamijo, Serge Brand, Uwe Pühse
OBJECTIVES: To examine the effects of a structured exercise program implemented during school break-time on working memory maintenance and neurophysiological indices of task preparation processes in adolescents. DESIGN: Using class-wise random allocation, participants from four classes were divided into an exercise (n=20) and a wait-list control group (n=16). Over a period of eight weeks, the exercise group engaged in 20min of combined aerobic and coordinative exercise on each school day...
January 10, 2018: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29352196/hyper-hippocampal-glycogen-induced-by-glycogen-loading-with-exhaustive-exercise
#19
Mariko Soya, Takashi Matsui, Takeru Shima, Subrina Jesmin, Naomi Omi, Hideaki Soya
Glycogen loading (GL), a well-known type of sports conditioning, in combination with exercise and a high carbohydrate diet (HCD) for 1 week enhances individual endurance capacity through muscle glycogen supercompensation. This exercise-diet combination is necessary for successful GL. Glycogen in the brain contributes to hippocampus-related memory functions and endurance capacity. Although the effect of HCD on the brain remains unknown, brain supercompensation occurs following exhaustive exercise (EE), a component of GL...
January 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29346524/-effects-of-a-primary-care-based-multifactorial-intervention-on-physical-and-cognitive-function-in-frail-elderly-individuals-a-randomized-controlled-trial
#20
Laura Romera-Liebana, Francesc Orfila, Josep Maria Segura, Jordi Real, Maria Lluïsa Fabra, Mercedes Möller, Santiago Lancho, Anna Ramirez, Nuria Marti, Montserrat Cullell, Nuria Bastida, Dolors Martinez, Maria Giné, Patricia Cendrós, Anna Bistuer, Elena Perez, Maria Assumpta Fabregat, Gonçal Foz
Background: Detecting and managing frailty at early stages can prevent disability and other adverse outcomes. The study aim was to evaluate whether a multifactorial intervention program could modify physical and cognitive frailty parameters in elderly individuals. Methods: We conducted a multicenter, randomized, single-blind, parallel-group trial in community-living pre-frail/frail elderly individuals in Barcelona. A total of 352 patients, aged ≥65 years old with positive frailty screening, was randomized into two groups to receive a 12-week multidisciplinary intervention or usual care, with concealed allocation...
January 16, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
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