keyword
MENU ▼
Read by QxMD icon Read
search

Mobius

keyword
https://www.readbyqxmd.com/read/28218996/hypoxia-stimulated-membrane-trafficking-requires-t-plastin
#1
Marieke Wottawa, Stephanie Naas, Johannes Böttger, Gijsbert J van Belle, Wiebke Möbius, Natalia H Revelo, Doris Heidenreich, Melanie von Ahlen, Anke Zieseniss, Katharina Kröhnert, Susanne Lutz, Christof Lenz, Henning Urlaub, Silvio O Rizzoli, Dörthe M Katschinski
Traffic between the plasma membrane and the endomembrane compartments is an essential feature of eukaryotic cells. The secretory pathway sends cargoes from biosynthetic compartments to the plasma membrane. This is counterbalanced by a retrograde endocytotic route and is essential for cell homeostasis. Cells need to adapt rapidly to environmental challenges like the reduction of pO2 which, however, has not been analyzed in relation to membrane trafficking in detail. Therefore we determined changes in the plasma membrane trafficking in normoxia, hypoxia, and after reoxygenation METHODS: Membrane trafficking was analyzed by using the bulk membrane endocytosis marker FM 1-43, the newly developed membrane probe mCLING, wheat germ agglutinin as well as fluorescently labeled choleratoxin subunit B...
February 20, 2017: Acta Physiologica
https://www.readbyqxmd.com/read/28165184/the-extension-of-baird-s-rule-to-twisted-heteroannulenes-aromaticity-reversal-of-singly-and-doubly-twisted-molecular-systems-in-the-lowest-triplet-state
#2
Yongseok Hong, Juwon Oh, Young Mo Sung, Yasuo Tanaka, Atsuhiro Osuka, Dongho Kim
We have investigated the aromaticity of singly twisted Möbius aromatic and doubly twisted Hückel antiaromatic bis(palladium(II)) [36]octaphyrins in the lowest triplet state (T1 ) by spectroscopic measurements and quantum calculations. The T1 state of the singly twisted Möbius [36]octaphyrin shows broad and weak absorption spectral features that are analogous to those of antiaromatic expanded porphyrins while the T1 state of the doubly twisted Hückel [36]octaphyrin exhibits intense and distinct spectral features, indicating the aromatic nature...
February 6, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28145065/positional-relations-of-the-cervical-vagus-nerve-revisited
#3
Uwe Planitzer, Niels Hammer, Ingo Bechmann, Juliane Glätzner, Sabine Löffler, Robert Möbius, Bernhard N Tillmann, David Weise, Dirk Winkler
OBJECTIVES: The cervical part of the vagus nerve (CVN) has become an important target for stimulation therapy to treat epilepsy and psychiatric conditions. For this purpose, the CVN is visualized in the carotid sheath, assuming it to be localized dorsomedially between the carotid artery (CA) and the internal jugular vein (JV). The aim of our morphological study was therefore to revisit the CVN relationships to the CA and JV, hypothesizing it to have common variations to this classical textbook anatomy...
February 1, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28144112/clinical-implementation-of-an-electron-monitor-unit-dosimetry-system-based-on-task-group-71-report-and-a-commercial-calculation-program
#4
Huijun Xu, Mariana Guerrero, Shifeng Chen, Xiaocheng Yang, Karl Prado, Colleen Schinkel
Many clinics still use monitor unit (MU) calculations for electron treatment planning and/or quality assurance (QA). This work (1) investigates the clinical implementation of a dosimetry system including a modified American Association of Physicists in Medicine-task group-71 (TG-71)-based electron MU calculation protocol (modified TG-71 electron [mTG-71E] and an independent commercial calculation program and (2) provides the practice recommendations for clinical usage. Following the recently published TG-71 guidance, an organized mTG-71E databook was developed to facilitate data access and subsequent MU computation according to our clinical need...
October 2016: Journal of Medical Physics
https://www.readbyqxmd.com/read/28117328/dietary-cholesterol-promotes-repair-of-demyelinated-lesions-in-the-adult-brain
#5
Stefan A Berghoff, Nina Gerndt, Jan Winchenbach, Sina K Stumpf, Leon Hosang, Francesca Odoardi, Torben Ruhwedel, Carolin Böhler, Benoit Barrette, Ruth Stassart, David Liebetanz, Payam Dibaj, Wiebke Möbius, Julia M Edgar, Gesine Saher
Multiple Sclerosis (MS) is an inflammatory demyelinating disorder in which remyelination failure contributes to persistent disability. Cholesterol is rate-limiting for myelin biogenesis in the developing CNS; however, whether cholesterol insufficiency contributes to remyelination failure in MS, is unclear. Here, we show the relationship between cholesterol, myelination and neurological parameters in mouse models of demyelination and remyelination. In the cuprizone model, acute disease reduces serum cholesterol levels that can be restored by dietary cholesterol...
January 24, 2017: Nature Communications
https://www.readbyqxmd.com/read/28104946/mobious-syndrome-mr-findings
#6
Maskal Revanna Srinivas, Dhulappa Mudabasappagol Vaishali, Kadaba Shamachar Vedaraju, Bangalore Rangaswamy Nagaraj
Möbius syndrome is an extremely rare congenital disorder. We report a case of Möbius syndrome in a 2-year-old girl with bilateral convergent squint and left-sided facial weakness. The characteristic magnetic resonance imaging (MRI) findings of Möbius syndrome, which include absent bilateral abducens nerves and absent left facial nerve, were noted. In addition, there was absence of left anterior inferior cerebellar artery (AICA) and absence of bilateral facial colliculi. Clinical features, etiology, and imaging findings are discussed...
October 2016: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/28076777/antagonistic-functions-of-mbp-and-cnp-establish-cytosolic-channels-in-cns-myelin
#7
Nicolas Snaidero, Caroline Velte, Matti Myllykoski, Arne Raasakka, Alexander Ignatev, Hauke B Werner, Michelle S Erwig, Wiebke Möbius, Petri Kursula, Klaus-Armin Nave, Mikael Simons
The myelin sheath is a multilamellar plasma membrane extension of highly specialized glial cells laid down in regularly spaced segments along axons. Recent studies indicate that myelin is metabolically active and capable of communicating with the underlying axon. To be functionally connected to the neuron, oligodendrocytes maintain non-compacted myelin as cytoplasmic nanochannels. Here, we used high-pressure freezing for electron microscopy to study these cytoplasmic regions within myelin close to their native state...
January 10, 2017: Cell Reports
https://www.readbyqxmd.com/read/28048620/su-f-t-308-mobius-fx-evaluation-and-comparison-against-a-commercial-4d-detector-array-for-vmat-plan-qa
#8
L Vazquez Quino, C Huerta Hernandez, A Morrow, B Massingill, D Rangaraj
PURPOSE: To evaluate the use of MobiusFX as a pre-treatment verification IMRT QA tool and compare it with a commercial 4D detector array for VMAT plan QA. METHODS: 15 VMAT plan QA of different treatment sites were delivered and measured by traditional means with the 4D detector array ArcCheck (Sun Nuclear corporation) and at the same time measurement in linac treatment logs (Varian Dynalogs files) were analyzed from the same delivery with MobiusFX software (Mobius Medical Systems)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048548/su-a-brc-02-the-path-of-a-chief-of-medical-physics
#9
D Shepard
: This year's Annual Student Meeting consists of a panel of professionals who have pursued a traditional education in medical physics and have since pursued a variety of careers. These range from chief medical physicist, small business founder, FDA scientist, industry R&D scientist, and academic researcher. Each panelist will discuss their education, positions that they have held leading to their current one, and factors that influenced them to pursue their careers. Time will be left at the end of the talk to open the floor for questions from students and trainees...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048368/su-a-brc-05-the-path-of-a-fda-physicist
#10
R Ochs
: This year's Annual Student Meeting consists of a panel of professionals who have pursued a traditional education in medical physics and have since pursued a variety of careers. These range from chief medical physicist, small business founder, FDA scientist, industry R&D scientist, and academic researcher. Each panelist will discuss their education, positions that they have held leading to their current one, and factors that influenced them to pursue their careers. Time will be left at the end of the talk to open the floor for questions from students and trainees...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047961/su-f-t-285-evaluation-of-a-patient-dvh-based-imrt-qa-system
#11
H Zhen, G Redler, J Chu, J Turian
PURPOSE: To evaluate the clinical performance of a patient DVH-based QA system for prostate VMAT QA. METHODS: Mobius3D(M3D) is a QA software with an independent beam model and dose engine. The MobiusFX(MFX) add-on predicts patient dose using treatment machine log files. We commissioned the Mobius beam model in two steps. First, the stock beam model was customized using machine commissioning data, then verified against the TPS with 12 simple phantom plans and 7 clinical 3D plans...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047951/tu-h-campus-tep1-04-novel-3d-printed-plastic-cutouts-filled-with-aluminum-oxide-for-same-day-electron-radiotherapy
#12
J Mikell, C Lee, K Lam
PURPOSE: Clinics that outsource electron cutout manufacturing may be unable to simulate and treat patients on the same day. To enable same day treatment, we investigate the use of 3D printed hollow cutouts filled with 30 grit Al2 O3 powder. We verified the dosimetric equivalence of such a cutout relative to an outsourced Copper cutout. METHODS: Printing was performed using a Ultibots Kossel 250 V-Slot 3D printer and polylactic acid filament. Printing files were derived from an in-house 3D model designed to mate with a Varian 6 cm electron cone...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047886/su-a-brc-03-the-path-of-a-small-business-owner
#13
N Childress
: This year's Annual Student Meeting consists of a panel of professionals who have pursued a traditional education in medical physics and have since pursued a variety of careers. These range from chief medical physicist, small business founder, FDA scientist, industry R&D scientist, and academic researcher. Each panelist will discuss their education, positions that they have held leading to their current one, and factors that influenced them to pursue their careers. Time will be left at the end of the talk to open the floor for questions from students and trainees...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047722/su-a-brc-06-the-path-of-an-academic-physicist
#14
R Howell
: This year's Annual Student Meeting consists of a panel of professionals who have pursued a traditional education in medical physics and have since pursued a variety of careers. These range from chief medical physicist, small business founder, FDA scientist, industry R&D scientist, and academic researcher. Each panelist will discuss their education, positions that they have held leading to their current one, and factors that influenced them to pursue their careers. Time will be left at the end of the talk to open the floor for questions from students and trainees...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047241/su-f-t-306-validation-of-mobius-3d-and-fx-for-elekta-linear-accelerators
#15
C Nelson, M Garcia, E Calderon, S Kirsner
PURPOSE: Log file based IMRT and VMAT QA is a system that analyzes treatment log files and uses delivery parameters to compute the dose to the patient/phantom. This system was previously commissioned for Varian machines, the purpose of this work is to describe the process for commissioning Mobius for use with Elekta machines. METHODS: Twelve IMRT and VMAT plans (6×) were planned and delivered and dose was measured using MapCheck, the results were compared to that computed by Mobius...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047222/su-a-brc-04-the-path-of-a-research-and-development-physicist
#16
K Ruchala
: This year's Annual Student Meeting consists of a panel of professionals who have pursued a traditional education in medical physics and have since pursued a variety of careers. These range from chief medical physicist, small business founder, FDA scientist, industry R&D scientist, and academic researcher. Each panelist will discuss their education, positions that they have held leading to their current one, and factors that influenced them to pursue their careers. Time will be left at the end of the talk to open the floor for questions from students and trainees...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047147/su-a-brc-00-aapm-medical-physics-student-meeting-the-many-paths-of-medical-physics
#17
Alison Roth
: This year's Annual Student Meeting consists of a panel of professionals who have pursued a traditional education in medical physics and have since pursued a variety of careers. These range from chief medical physicist, small business founder, FDA scientist, industry R&D scientist, and academic researcher. Each panelist will discuss their education, positions that they have held leading to their current one, and factors that influenced them to pursue their careers. Time will be left at the end of the talk to open the floor for questions from students and trainees...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047074/su-a-brc-07-q-a
#18
A Roth
: This year's Annual Student Meeting consists of a panel of professionals who have pursued a traditional education in medical physics and have since pursued a variety of careers. These range from chief medical physicist, small business founder, FDA scientist, industry R&D scientist, and academic researcher. Each panelist will discuss their education, positions that they have held leading to their current one, and factors that influenced them to pursue their careers. Time will be left at the end of the talk to open the floor for questions from students and trainees...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046939/su-g-tep4-11-implementation-of-a-non-measurement-based-patient-specific-imrt-qa-program
#19
S Chen, M Guerrero, B Zhang, B Yi, S Mossahebi, K Prado, W D'Souza, K Langen
PURPOSE: To implement a comprehensive non-measurement-based verification program for patient-specific IMRT QA METHODS: Based on published guidelines, a robust IMRT QA program should assess the following components: 1) accuracy of dose calculation, 2) accuracy of data transfer from the treatment planning system (TPS) to the record-and-verify (RV) system, 3) treatment plan deliverability, and 4) accuracy of plan delivery. RESULTS: We have implemented an IMRT QA program that consist of four components: 1) an independent re-calculation of the dose distribution in the patient anatomy with a commercial secondary dose calculation program: Mobius3D (Mobius Medical Systems, Houston, TX), with dose accuracy evaluation using gamma analysis, PTV mean dose, PTV coverage to 95%, and organ-at-risk mean dose; 2) an automated in-house-developed plan comparison system that compares all relevant plan parameters such as MU, MLC position, beam iso-center position, collimator, gantry, couch, field size settings, and bolus placement, etc...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046485/su-a-brc-01-welcome-and-introduction-to-student-and-trainees-day
#20
A Roth
: This year's Annual Student Meeting consists of a panel of professionals who have pursued a traditional education in medical physics and have since pursued a variety of careers. These range from chief medical physicist, small business founder, FDA scientist, industry R&D scientist, and academic researcher. Each panelist will discuss their education, positions that they have held leading to their current one, and factors that influenced them to pursue their careers. Time will be left at the end of the talk to open the floor for questions from students and trainees...
June 2016: Medical Physics
keyword
keyword
74969
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"