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https://www.readbyqxmd.com/read/28930886/upper-eyelid-splitting-to-facilitate-the-insertion-of-glaucoma-drainage-devices
#1
Lorraine M Provencher, Keith D Carter, Jeffrey A Nerad, Wallace L M Alward
PURPOSE: To describe a new application for vertical splitting of the upper eyelid, a technique traditionally used for orbital access, in order to facilitate glaucoma drainage device implantation in patients with poor surgical exposure. METHODS: Case series. CASES: We present a case of Möbius syndrome with complete restriction of the extraocular muscles, followed by a case of cicatricial narrowing of the palpebral fissures due to chronic allergic dermatitis...
September 19, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28901136/tren-capped-hexaphyrin-zinc-complexes-interplaying-molecular-recognition-m%C3%A3-bius-aromaticity-and-chirality
#2
Hervé Ruffin, Gildas Nyame Mendendy Boussambe, Thierry Roisnel, Vincent Dorcet, Bernard Boitrel, Stéphane Le Gac
Over the past decade, the hexaphyrin skeleton has emerged as a multifaceted frame exhibiting strong interplay between topology, aromaticity, and metal coordination, opening new research areas beyond porphyrins. However, molecular recognition with hexaphyrins has been underexplored, mainly because of the lack of general synthetic strategies leading to sophisticated molecular hosts. Here we have developed a straightforward approach for capping the heteroannulene frame with tripodal units (e.g., tris(2-aminoethyl)amine [tren]) through postsynthetic modification of a readily accessible meso-(2-aminophenyl) tris-substituted platform...
September 22, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28860567/the-novel-link-between-planar-m%C3%A3-bius-aromatic-and-third-order-nonlinear-optical-properties-of-metal-bridged-polycyclic-complexes
#3
Li Wang, Jinting Ye, Hongqiang Wang, Haiming Xie, Yongqing Qiu
Metal-bridged polcyclic aromatic complexes, exhibiting unusual optical effects such as near-infrared photoluminescence with particularly large Stokes shifts, long lifetimes and aggregation enhancement, have been established as unique "carbonloong chemistry". Herein, the electronic structures, aromaticities, absorption spectra and third order nonlinear optical (NLO) responses of metal-bridged polcyclic aromatic complexes (M = Fe, Re, Os and Ir) are investigated using the density functional theory computations...
August 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28839035/complete-genome-sequence-of-jii-1961-a-bovine-mycobacterium-avium-subsp-paratuberculosis-field-isolate-from-germany
#4
Petra Möbius, Gabriele Nordsiek, Martin Hölzer, Michael Jarek, Manja Marz, Heike Köhler
Mycobacterium avium subsp. paratuberculosis causes Johne's disease in ruminants and was also detected in nonruminant species, including human beings, and in milk products. We announce here the 4.829-Mb complete genome sequence of the cattle-type strain JII-1961 from Germany, which is very similar to cattle-type strains recovered from different continents.
August 24, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28812103/re-expression-of-pro-fibrotic-embryonic-preserved-mediators-in-irradiated-arterial-vessels-of-the-head-and-neck-region
#5
Patrick Möbius, Raimund H M Preidl, Manuel Weber, Kerstin Amann, Friedrich W Neukam, Falk Wehrhan
PURPOSE: Surgical treatment of head and neck malignancies frequently includes microvascular free tissue transfer. Preoperative radiotherapy increases postoperative fibrosis-related complications up to transplant loss. Fibrogenesis is associated with re-expression of embryonic preserved tissue developmental mediators: osteopontin (OPN), regulated by sex-determining region Y‑box 9 (Sox9), and homeobox A9 (HoxA9) play important roles in pathologic tissue remodeling and are upregulated in atherosclerotic vascular lesions; dickkopf-1 (DKK1) inhibits pro-fibrotic and atherogenic Wnt signaling...
August 15, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28805825/the-processing-and-heterostructuring-of-silk-with%C3%A2-light
#6
Mehra S Sidhu, Bhupesh Kumar, Kamal P Singh
Spider silk is a tough, elastic and lightweight biomaterial, although there is a lack of tools available for non-invasive processing of silk structures. Here we show that nonlinear multiphoton interactions of silk with few-cycle femtosecond pulses allow the processing and heterostructuring of the material in ambient air. Two qualitatively different responses, bulging by multiphoton absorption and plasma-assisted ablation, are observed for low- and high-peak intensities, respectively. Plasma ablation allows us to make localized nanocuts, microrods, nanotips and periodic patterns with minimal damage while preserving molecular structure...
September 2017: Nature Materials
https://www.readbyqxmd.com/read/28802760/involvement-of-obliquus-capitis-inferior-muscle-in-dystonic-head-tremor
#7
A Schramm, D Huber, C Möbius, A Münchau, Z Kohl, T Bäumer
INTRODUCTION: Head tremor is a common feature in cervical dystonia (CD) and often less responsive to botulinum neurotoxin (BoNT) treatment than dystonic posturing. Ultrasound allows accurate targeting of deeper neck muscles. METHODS: In 35 CD patients with dystonic head tremor the depth and thickness of the splenius capitis (SPL), semispinalis capitis and obliquus capitis inferior muscles (OCI) were assessed using ultrasound. Ultrasound guided EMG recordings were performed from the SPL and OCI...
August 1, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28670056/clinical-experience-with-machine-log-file-software-for-volumetric-modulated-arc-therapy-techniques
#8
Luis Alberto Vazquez-Quino, Claudia Ivette Huerta-Hernandez, Dharanipathy Rangaraj
Mobius FX, an add-on software module from Mobius Medical Systems™ for intensity-modulated radiation therapy (IMRT) quality assurance (QA), uses linac treatment logs to efficiently calculate and verify the 3D dose delivered to patients. An advantage of the Mobius FX module is that it does not require device positioning. In this study, we compared the Mobius FX with another QA option, ArcCheck, as well as with the treatment planning system (TPS) using 30 volumetric-modulated arc therapy (VMAT) plans planned and delivered on a Varian TrueBeam linac...
July 2017: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/28635352/a-randomized-controlled-trial-comparing-two-types-of-retractors-at-caesarean-delivery
#9
Abbey J Hardy-Fairbanks, Todd Mackenzie, Martin McCarthy, Marlene B Goldman, Michele R Lauria
The aim of this study was to determine if the use of a self-retaining, symmetrical retractor (OB/Mobius(®)) during caesarean delivery is associated with differences in post-operative pain experience. Consenting women undergoing caesarean delivery were randomly assigned to OB/Mobius(®) versus conventional retraction instruments. Women were blinded to retractor type and filled out surgical pain surveys each post-operative day. Additional outcome variables were collected through a provider survey and chart review...
November 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28618111/iron-catalyzed-olefin-metathesis-with-low-valent-iron-alkylidenes
#10
Michael Mauksch, Svetlana B Tsogoeva
Inspired by recent reports of low-valent iron-complex-catalyzed formal [2+2] cycloaddition of olefins, we demonstrate computationally that with such low-valent iron complexes and with "strong" ligands, the olefin metathesis is also preferred over the undesired cyclopropanation side-reaction, competition already studied by Hoffmann and co-workers almost 40 years ago (J. Am. Chem. Soc. 1981, 103, 5582). The [2+2] cycloaddition step in metathesis propagation, which gives a Chauvin-type metallacyclobutane intermediate, is proposed to proceed either via a planar four-electron Craig-Möbius aromatic [π2s +π2s ] transition-state structure with a low barrier of 4...
June 15, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28587628/osteoclast-profile-of-medication-related-osteonecrosis-of-the-jaw-secondary-to-bisphosphonate-therapy-a-comparison-with-osteoradionecrosis-and-osteomyelitis
#11
Christian Gross, Manuel Weber, Kay Creutzburg, Patrick Möbius, Raimund Preidl, Kerstin Amann, Falk Wehrhan
BACKGROUND: The medication-related osteonecrosis of the jaw secondary to bisphosphonate therapy [MRONJ (BP)] is characterized by non-healing exposed bone in the maxillofacial region. The pathogenesis of MRONJ (BP) is not fully understood. Giant, hypernucleated, inactive osteoclasts were found in MRONJ (BP) tissues, which indicated that accelerated cell-cell fusion might play a role. Dendritic cell-specific transmembrane protein (DC-STAMP) is associated with the cell-cell fusion of osteoclasts and precursor cells...
June 6, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/28538051/mobius-syndrome-a-35-year-single-institution-experience
#12
Philip K McClure, Eray Kilinc, Scott Oishi, Anthony I Riccio, Lori A Karol
BACKGROUND: Mobius syndrome is a rare syndrome that is known to be associated with a variety of orthopaedic conditions including scoliosis, clubfoot, transverse limb deficiencies, Poland syndrome, and a myriad of hand conditions. To date, no large series exist to characterize the orthopaedic manifestations of Mobius syndrome. METHODS: Medical records at a single tertiary pediatric institution were reviewed for all patients diagnosed with Mobius syndrome from January 1, 1980 to December 31, 2015...
October 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28534340/imaging-of-cranial-nerves-iii-iv-vi-in-congenital-cranial-dysinnervation-disorders
#13
REVIEW
Jae Hyoung Kim, Jeong Min Hwang
Congenital cranial dysinnervation disorders are a group of diseases caused by abnormal development of cranial nerve nuclei or their axonal connections, resulting in aberrant innervation of the ocular and facial musculature. Its diagnosis could be facilitated by the development of high resolution thin-section magnetic resonance imaging. The purpose of this review is to describe the method to visualize cranial nerves III, IV, and VI and to present the imaging findings of congenital cranial dysinnervation disorders including congenital oculomotor nerve palsy, congenital trochlear nerve palsy, Duane retraction syndrome, Möbius syndrome, congenital fibrosis of the extraocular muscles, synergistic divergence, and synergistic convergence...
June 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/28513664/a-resilient-and-luminescent-stimuli-responsive-hydrogel-from-a-heterotopic-1-8-naphthalimide-derived-ligand
#14
Chris S Hawes, Amy D Lynes, Kevin Byrne, Wolfgang Schmitt, Gavin Ryan, Matthias E Möbius, Thorfinnur Gunnlaugsson
A heterotopic naphthalimide ligand N-(4-picolyl)-4-(4'-carboxyphenoxy)-1,8-naphthalimide HL is utilised for the formation of self-assembled soft materials. In the presence of K(+) ions, L(-) forms a robust photoluminescent hydrogel 1 which is reversible under thermal, mechanical or chemical stimuli.
May 17, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28484846/erratum-to-antibody-mediated-neutralization-of-myelin-associated-ephrinb3-accelerates-cns-remyelination
#15
Yasir A Syed, Chao Zhao, Don Mahad, Wiebke Möbius, Friedrich Altmann, Franziska Foss, G A González, Aycan Sentürk, Amparo Acker-Palmer, Gert Lubec, Kathryn Lilley, Robin J M Franklin, Klaus-A Nave, Mark R N Kotter
No abstract text is available yet for this article.
July 2017: Acta Neuropathologica
https://www.readbyqxmd.com/read/28479114/bronchopulmonary-dysplasia-where-have%C3%A2-all-the-stem-cells-gone-origin-and-potential-function-of-resident-lung-stem-cells
#16
Marius Alexander Möbius, Bernard Thébaud
Celebrating its 50th anniversary in 2017, bronchopulmonary dysplasia (BPD)-the chronic lung disease of prematurity that follows ventilator and oxygen therapy for acute respiratory failure-remains the most frequent complication of extreme prematurity. Survival of premature infants born at increasingly earlier stages of gestation has made the prevention of lung injury increasingly challenging. BPD is postulated to be a misdirection of many functions in the developing lung, including growth factor signalling and matrix as well as cellular composition, resulting in impaired alveolar and lung vascular growth...
May 4, 2017: Chest
https://www.readbyqxmd.com/read/28470148/peroxisomal-dysfunctions-cause-lysosomal-storage-and-axonal-kv1-channel-redistribution-in-peripheral-neuropathy
#17
Sandra Kleinecke, Sarah Richert, Livia de Hoz, Britta Brügger, Theresa Kungl, Ebrahim Asadollahi, Susanne Quintes, Judith Blanz, Rhona McGonigal, Kobra Naseri, Michael W Sereda, Timo Sachsenheimer, Christian Lüchtenborg, Wiebke Möbius, Hugh Willison, Myriam Baes, Klaus-Armin Nave, Celia Michèle Kassmann
Impairment of peripheral nerve function is frequent in neurometabolic diseases, but mechanistically not well understood. Here, we report a novel disease mechanism and the finding that glial lipid metabolism is critical for axon function, independent of myelin itself. Surprisingly, nerves of Schwann cell-specific Pex5 mutant mice were unaltered regarding axon numbers, axonal calibers, and myelin sheath thickness by electron microscopy. In search for a molecular mechanism, we revealed enhanced abundance and internodal expression of axonal membrane proteins normally restricted to juxtaparanodal lipid-rafts...
May 4, 2017: ELife
https://www.readbyqxmd.com/read/28446768/linear-dynamics-of-classical-spin-as-m%C3%A3-bius-transformation
#18
Alexey Galda, Valerii М Vinokur
Though the overwhelming majority of natural processes occur far from the equilibrium, general theoretical approaches to non-equilibrium phase transitions remain scarce. Recent breakthroughs introduced a description of open dissipative systems in terms of non-Hermitian quantum mechanics enabling the identification of a class of non-equilibrium phase transitions associated with the loss of combined parity (reflection) and time-reversal symmetries. Here we report that the time evolution of a single classical spin (e...
April 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28436155/the-mobius-airo-mobile-ct-for-image-guided-proton-therapy-characterization-commissioning
#19
Jasmine A Oliver, Omar A Zeidan, Sanford L Meeks, Amish P Shah, Jason Pukala, Patrick Kelly, Naren R Ramakrishna, Twyla R Willoughby
PURPOSE: The purpose of this study was to characterize the Mobius AIRO Mobile CT System for localization and image-guided proton therapy. This is the first known application of the AIRO for proton therapy. METHODS: Five CT images of a Catphan(®) 504 phantom were acquired on the AIRO Mobile CT System, Varian EDGE radiosurgery system cone beam CT (CBCT), Philips Brilliance Big Bore 16 slice CT simulator, and Siemens SOMATOM Definition AS 20 slice CT simulator. DoseLAB software v...
April 24, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28422748/therapeutic-inhibition-of-soluble-brain-tnf-promotes-remyelination-by-increasing-myelin-phagocytosis-by-microglia
#20
Maria Karamita, Christopher Barnum, Wiebke Möbius, Malú G Tansey, David E Szymkowski, Hans Lassmann, Lesley Probert
Multiple sclerosis (MS) is an inflammatory CNS demyelinating disease in which remyelination largely fails. Transmembrane TNF (tmTNF) and TNF receptor 2 are important for remyelination in experimental MS models, but it is unknown whether soluble TNF (solTNF), a major proinflammatory factor, is involved in regeneration processes. Here, we investigated the specific contribution of solTNF to demyelination and remyelination in the cuprizone model. Treatment with XPro1595, a selective inhibitor of solTNF that crosses the intact blood-brain barrier (BBB), in cuprizone-fed mice did not prevent toxin-induced oligodendrocyte loss and demyelination, but it permitted profound early remyelination due to improved phagocytosis of myelin debris by CNS macrophages and prevented disease-associated decline in motor performance...
April 20, 2017: JCI Insight
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