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Artificial disc replacement

Wei Yuan, Haiping Zhang, Xiaoshu Zhou, Weidong Wu, Yue Zhu
OBJECTIVE: Artificial cervical disc replacement is expected to maintain normal cervical biomechanics. The effect of Prestige LP prosthesis height on cervical biomechanics has not been thoroughly studied yet. This finite element (FE) study of the cervical biomechanics aims to predict how the parameters like range of motion (ROM), adjacent intradiscal pressure, facet joint force and bone-implant interface stress are affected by different Prestige LP prosthesis heights. METHODS: The FE model of intact cervical spine (C3-C7) was obtained from our previous study, and the model was altered to implant Prestige LP prostheses at the C5-C6 level...
February 17, 2018: World Neurosurgery
Da Bao, Dawei Li
Artificial disc replacement alone is unable to completely cure cervical degenerative diseases; thus, a stabilization device markedly improves patient recovery. In order to meet this requirement, an anterior spinal instrumentation combining a prosthetic disc nucleus with a flexible stabilization device (ASI combining PDN/FD) was developed. An artificial disc was designed and manufactured using polyvinyl alcohol hydrogel (PVA-H) with a repeated freeze-melting technique, and subsequently the dehydration and swelling properties of the PVA-H were investigated...
March 2018: Experimental and Therapeutic Medicine
Kai-Feng Wang, Shuo Duan, Zhen-Qi Zhu, Hai-Ying Liu, Chen-Jun Liu, Shuai Xu
OBJECTIVE: To assess the mid-long-term follow-up of the safety and efficacy of anterior cervical discectomy and fusion (ACDF), cervical artificial disc replacement (CADR) and hybrid surgery (HS) for bi-level cervical degenerative disc disease (cDDD). METHODS: 77 patients who underwent ACDF, HS and CADR were retrospectively reviewed. Clinical effects were evaluated based on NDI, VAS and JOA scores, and the Odom criteria. Radiographic outcomes were evaluated, including cervical range of motion(ROM), operative and adjacent segments ROM, incidence of adjacent segments degeneration(ASD) and heterotopic ossification(HO)...
January 30, 2018: World Neurosurgery
Yu Wang, Xiao-Dong Yi, Chun-De Li
OBJECTIVE: This study aimed to investigate the effects involved with the artificial nucleus pulposus (NP) replacement on stress distribution of the cartilaginous endplate (CEP) in a 3-dimensional lumbar intervertebral disc (IVD) model using a finite element (FE) analysis. METHODS: A healthy male volunteer was recruited for the purposes of the study and a spiral computed tomography scan was subsequently conducted to obtain the data information in relation to the L4/5 motion segment...
December 2017: Medicine (Baltimore)
Bei-Yu Wang, Ting-Kui Wu, Hao Liu, Yu-Xiao Deng, Chen Ding
RATIONALE: Artificial cervical disc replacement (ACDR) has been reported to be an effective and safe surgical treatment for cervical spondylosis. However, iatrogenic fracture during ACDR surgery has rarely been reported. Considering its infrequency, we report a rare clinical case, with the aim of sharing our experience and exploring when to convert ACDR to fusion intraoperatively. PATIENTS CONCERNS: A 47-year-old woman felt neck pain with weakness and numbness in both upper limbs for 5 months...
November 2017: Medicine (Baltimore)
J Timothy, V Petralia, J R Wilson
CASE: Eighteen months after implantation of a C6-C7 cervical artificial disc (ProDisc-C; DePuy Synthes), a 44-year-old woman presented with right-sided C7 radiculopathy. Imaging revealed posterior subsidence of the prosthesis, with C7 foraminal stenosis. An ultrasonic curet was used to safely and effectively extract the prosthesis without neurologic complication; safe access for the insertion of an intervertebral cage was facilitated. CONCLUSION: The ultrasonic curet was a safe and effective adjunct for revision artificial cervical disc replacement surgery; this technique may help to reduce potential injury to neural structures in a procedure with a traditionally high complication rate...
January 24, 2018: JBJS Case Connector
Jack William Kerferd, David Abi-Hanna, Kevin Phan, Prashanth Rao, Ralph J Mobbs
In recent decades cervical arthroplasty, or cervical disc replacement, has been steadily increasing in popularity as a procedure for the treatment of degenerative pathologies of the cervical spine. This is based on an evolving body of literature that documents superior outcomes in cervical disc replacement over fusion, for both single and double level pathologies, in well selected patients. One of the more recent and popular implants currently on the market is the Mobi-C cervical artificial disc (LDR Medical; Troyes, France)...
December 2017: Journal of Spine Surgery (Hong Kong)
Jinhao Miao, Ye Shen, Chao Li, Lei Fang, Lei Zhang, Xiangyi Zhang, Yiman Li, Yong Kuang
STUDY DESIGN: A prospective cohort study with 79 patients. OBJECTIVE: To analyze the midterm incidence of heterotopic ossification (HO) after cervical artificial disc replacement with Discover prosthesis in treatment of cervical degenerative disc disease. MATERIALS AND METHODS: A cohort of 79 patients with 102 Discover prostheses (56 monosegment and 23 bisegments) was evaluated. Clinical and radiographic follow-up was performed. The performance of HO of the operative segments was assessed annually after the operation for 4 years...
January 8, 2018: Clinical Spine Surgery
Domagoj Coric, Richard D Guyer, Pierce D Nunley, David Musante, Cameron Carmody, Charles Gordon, Carl Lauryssen, Margaret O Boltes, Donna D Ohnmeiss
OBJECTIVE Seven cervical total disc replacement (TDR) devices have received FDA approval since 2006. These devices represent a heterogeneous assortment of implants made from various biomaterials with different biomechanical properties. The majority of these devices are composed of metallic endplates with a polymer core. In this prospective, randomized multicenter study, the authors evaluate the safety and efficacy of a metal-on-metal (MoM) TDR (Kineflex|C) versus anterior cervical discectomy and fusion (ACDF) in the treatment of single-level spondylosis with radiculopathy through a long-term (5-year) follow-up...
January 5, 2018: Journal of Neurosurgery. Spine
Hui Lu, Lihua Peng
BACKGROUND: Total disc replacement (TDR) using Mobi-C cervical artificial disc might be promising to treat symptomatic degenerative disc disease. However, the results remained controversial. We conducted a systematic review and meta-analysis to compare the efficacy and safety of Mobi-C cervical artificial disc and anterior cervical discectomy and fusion (ACDF) in patients with symptomatic degenerative disc disease. METHODS: PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases were systematically searched...
December 2017: Medicine (Baltimore)
Gauri Tendulkar, Vrinda Sreekumar, Frank Rupp, Arun K Teotia, Kiriaki Athanasopulu, Ralf Kemkemer, Alfred Buck, Alfred Buck, Hans-Peter Kaps, Jürgen Geis-Gerstorfer, Ashok Kumar, Andreas K Nussler
Effective restoration of human intervertebral disc degeneration is challenged by numerous limitations of the currently available spinal fusion and arthroplasty treatment strategies. Consequently, use of artificial biomaterial implant is gaining attention as a potential therapeutic strategy. Our study is aimed at investigating and characterizing a novel knitted titanium (Ti6Al4V) implant for the replacement of nucleus pulposus to treat early stages of chronic intervertebral disc degeneration. Specific knitted geometry of the scaffold with a porosity of 67...
November 30, 2017: Scientific Reports
Seo-Ryang Jang, Sang-Bok Lee, Kyoung-Suok Cho
Objective: The purpose of this study is to evaluate the efficacy and safety of 3-level hybrid surgery (HS), which combines fusion and cervical disc replacement (CDR), compared to 3-level fusionin patient with cervical spondylosis involving 3 levels. Methods: Patients in the anterior cervical discectomy and fusion (ACDF) group (n=30) underwent 3-level fusion and the HS group (n=19) underwent combined surgery with fusion and CDR. Clinical outcomes were evaluated using the visual analogue scale for the arm, the neck disability index (NDI), Odom criteria and postoperative complications...
November 2017: Journal of Korean Neurosurgical Society
Zikun Shang, Yingze Zhang, Di Zhang, Wenyuan Ding, Yong Shen
BACKGROUND The aim of this study was to retrospectively analyze the clinical and radiological efficacy of Bryan cervical artificial disc replacement (ADR) for "skip" multi-segment cervical spondylosis (SCS). MATERIAL AND METHODS We enrolled 49 patients with SCS treated with either Bryan cervical ADR (18 cases) or ACDF (31 cases). Each case was evaluated preoperatively and at more than 48 months postoperatively in follow-up using the JOA, NDI, and VAS. Cervical sagittal curvature, total cervical ROM, and degree of middle segments of motion were also evaluated...
November 4, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Jigang Lou, Yuanchao Li, Beiyu Wang, Yang Meng, Tingkui Wu, Hao Liu
In vitro biomechanical analysis after cervical disc replacement (CDR) with a novel artificial disc prosthesis (mobile core) was conducted and compared with the intact model, simulated fusion, and CDR with a fixed-core prosthesis. The purpose of this experimental study was to analyze the biomechanical changes after CDR with a novel prosthesis and the differences between fixed- and mobile-core prostheses.Six human cadaveric C2-C7 specimens were biomechanically tested sequentially in 4 different spinal models: intact specimens, simulated fusion, CDR with a fixed-core prosthesis (Discover, DePuy), and CDR with a mobile-core prosthesis (Pretic-I, Trauson)...
October 2017: Medicine (Baltimore)
Isobel Turner, David Choi
BACKGROUND: Anterior cervical disc replacement is an alternative to fusion for the treatment of selected cases of radiculopathy and myelopathy. We report clinical and radiological outcomes after disc replacement with the NuNec™ artificial cervical disc (Pioneer® Surgical Technology, Marquette, Michigan) with subgroup analysis. OBJECTIVE: To review clinical and radiological outcomes after anterior cervical disc replacement with the NuNec™ artificial cervical disc...
August 3, 2017: Neurosurgery
Yener N Yeni, Timothy Baumer, Daniel Oravec, Azam Basheer, Colin P McDonald, Michael J Bey, Stephen W Bartol, Victor Chang
BACKGROUND: Changes in the dimensions of the cervical neural foramina (CNF) are considered to be a key factor in nerve root compression and development of cervical radiculopathy. However, to what extent foraminal geometry differs between patients who underwent anterior cervical discectomy and fusion (ACDF) and those who underwent total disc arthroplasty with an artificial disc (AD) during physiological motion is largely unknown. PURPOSE: The objective of this study is to compare CNF dimensions during physiological neck motion between ACDF and AD...
September 4, 2017: Spine Journal: Official Journal of the North American Spine Society
Tianyi Niu, Haydn Hoffman, Daniel C Lu
BACKGROUND: Cervical total disc replacement (TDR) is an established alternative to anterior cervical discectomy and fusion (ACDF) with excellent long-term outcomes and low failure rates. Cases of implant failure and migration are scarce and primarily limited to several years postoperatively. The authors report a case of anterior extrusion of a C4-C5 ProDisc-C (DePuy Synthes, West Chester, PA, USA) cervical artificial disc (CAD) 14 months after placement due to minor trauma. CASE DESCRIPTION: A 33-year-old female who had undergone C4-C5 CAD implantation presented with neck pain and spasm after experiencing a paragliding accident...
2017: Surgical Neurology International
Regina F MacBarb, Derek P Lindsey, Chelsea S Bahney, Shane A Woods, Mark L Wolfe, Scott A Yerby
BACKGROUND: An aging society and concomitant rise in the incidence of impaired bone health have led to the need for advanced osteoconductive spinal implant surfaces that promote greater biological fixation (e.g. for interbody fusion cages, sacroiliac joint fusion implants, and artificial disc replacements). Additive manufacturing, i.e. 3D-printing, may improve bone integration by generating biomimetic spinal implant surfaces that mimic bone morphology. Such surfaces may foster an enhanced cellular response compared to traditional implant surfacing processes...
2017: International Journal of Spine Surgery
Haibo Li, Yiping Weng, Dong Zhou, Luming Nong, Nanwei Xu
No abstract text is available yet for this article.
July 28, 2017: Panminerva Medica
Xin Rong, Jigang Lou, Huibo Li, Yang Meng, Hao Liu
In cervical artificial disc replacement (C-ADR), sometimes we encountered with such cases that implants of adjacent height both fit the target disc space properly. No study was available discussing the choice of implant height and the clinical outcomes under such circumstance. The purpose of this study was to evaluate the impact of different implant heights on the clinical outcomes and radiographic results when the implants of adjacent height both fit the disc space properly. This retrospective study included 34 patients underwent single-level C-ADR at the C5-C6 level at our institution...
July 2017: Medicine (Baltimore)
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