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Artificial disc replacement

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https://www.readbyqxmd.com/read/28413754/an-approach-toward-replacing-vanadium-a-single-organic-molecule-for-the-anode-and-cathode-of-an-aqueous-redox-flow-battery
#1
Tobias Janoschka, Christian Friebe, Martin D Hager, Norbert Martin, Ulrich S Schubert
By combining a viologen unit and a 2,2,6,6-tetramethylpiperidin-1-oxyl (TEMPO) radical in one single combi-molecule, an artificial bipolar redox-active material, 1-(4-(((1-oxyl-2,2,6,6-tetramethylpiperidin-4-yl)oxy)carbonyl)benzyl)-1'-methyl-[4,4'-bipyridine]-1,1'-diium-chloride (VIOTEMP), was created that can serve as both the anode (-0.49 V) and cathode (0.67 V vs. Ag/AgCl) in a water-based redox-flow battery. While it mimics the redox states of flow battery metals like vanadium, the novel aqueous electrolyte does not require strongly acidic media and is best operated at pH 4...
April 2017: ChemistryOpen
https://www.readbyqxmd.com/read/28387616/long-term-clinical-and-radiographic-outcomes-of-the-prestige-lp-artificial-cervical-disc-replacement-at-2-levels-results-from-a-prospective-randomized-controlled-clinical-trial
#2
Todd H Lanman, J Kenneth Burkus, Randall G Dryer, Matthew F Gornet, Jeffrey McConnell, Scott D Hodges
OBJECTIVE The aim of this study was to assess long-term clinical safety and effectiveness in patients undergoing anterior cervical surgery using the Prestige LP artificial disc replacement (ADR) prosthesis to treat degenerative cervical spine disease at 2 adjacent levels compared with anterior cervical discectomy and fusion (ACDF). METHODS A prospective, randomized, controlled, multicenter FDA-approved clinical trial was conducted at 30 US centers, comparing the low-profile titanium ceramic composite-based Prestige LP ADR (n = 209) at 2 levels with ACDF (n = 188)...
April 7, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28365433/percutaneous-endoscopic-cervical-discectomy-pecd-an-analysis-of-outcome-causes-of-reoperation
#3
Hyeong Seok Oh, Byeong Wook Hwang, Sang Joon Park, Chang Sheng Hsieh, Sang Ho Lee
OBJECTIVE: Percutaneous endoscopic cervical discectomy (PECD) regarded as an effective treatment modality in cervical disc herniation, including radicular pain and lateral location of disc herniation. This study aimed to evaluate the clinical and radiological outcomes with PECD, along with the causes of reoperation and the technique itself. METHODS: Between January 2007 and November 2012, 101 patients underwent PECD at the Busan Wooridul hospital. Three patients underwent two-level PECD...
March 29, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28261429/radiological-parameters-of-undegenerated-cervical-vertebral-segments-in-a-korean-population
#4
Sung Hoon Choi, HeeSang Lee, Jae Hwan Cho, Jin Il Jung, Dong-Ho Lee
BACKGROUND: Several scoring systems for cervical disc and facet joint degeneration, using radiography or computed tomography, have been developed and tested for reliability. However, definitions of disc height and facet joint space narrowing vary. To our knowledge, no study has reported quantitative data for normal radiologic values of the cervical spine in the Korean population. The purpose of this study is to determine normal cervical disc height, disc height ratio, and facet joint space values, and investigate the correlation between demographic data and these values...
March 2017: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/28254671/are-patient-reported-outcomes-predictive-of-patient-satisfaction-5-years-after-anterior-cervical-spine-surgery
#5
Gregory D Schroeder, Dom Coric, Han Jo Kim, Todd J Albert, Kris E Radcliff
BACKGROUND CONTEXT: Patient satisfaction is becoming an increasing common proxy for surgical quality; however, the correlation between patient satisfaction and surgical outcomes 2 and 5 years after anterior cervical surgery has not been evaluated. PURPOSE: The study aimed to determine if patient satisfaction is predicted by improvement in patient-reported outcomes (PRO) 2 and 5 years after anterior cervical spine surgery. STUDY DESIGN: This is a retrospective analysis of prospectively collected data...
February 27, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28183604/wear-behaviour-of-uhmwpe-reinforced-by-carbon-nanofiller-and-paraffin-oil-for-joint-replacement
#6
Samy Yousef, Annamaria Visco, Giovanna Galtieri, Davide Nocita, Claudia Espro
The majority of artificial joints incorporate biomedical grade Ultra High Molecular Weight Poly Ethylene (UHMWPE), whose wear is considered most important in controlling service time of the whole joint. The aim of this work was to improve wear resistance of UHMWPE through the addition of 0.5-2.0wt% of Carbon Nano Filler (CNF) and 2% wt of Paraffin Oil (PO) using ball milling (BM) and extrusion techniques (EX). The wear tests on these nanocomposites were conducted by a pin on disc in dry (air) and wet media (simulated synovial fluid or artificial lubricant, and bovine synovial fluid or natural lubricant)...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28175519/345%C3%A2-elective-anterior-cervical-discectomy-and-fusion-vs-cervical-artificial-disc-replacement-a-comparison-of-perioperative-morbidity-and-early-outcomes
#7
Pavan S Upadhyayula, John K Yue, Reid Hoshide, Erik Curtis, Joseph D Ciacci
No abstract text is available yet for this article.
August 1, 2016: Neurosurgery
https://www.readbyqxmd.com/read/28142281/adjacent-level-arthroplasty-following-cervical-fusion
#8
Deshpande V Rajakumar, Akshay Hari, Murali Krishna, Subhas Konar, Ankit Sharma
OBJECTIVE Adjacent-level disc degeneration following cervical fusion has been well reported. This condition poses a major treatment dilemma when it becomes symptomatic. The potential application of cervical arthroplasty to preserve motion in the affected segment is not well documented, with few studies in the literature. The authors present their initial experience of analyzing clinical and radiological results in such patients who were treated with arthroplasty for new or persistent arm and/or neck symptoms related to neural compression due to adjacent-segment disease after anterior cervical discectomy and fusion (ACDF)...
February 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28142258/bone-loss-of-vertebral-bodies-at-the-operative-segment-after-cervical-arthroplasty-a-potential-complication
#9
Dong Hwa Heo, Dong Chan Lee, Jong Yang Oh, Choon Keun Park
OBJECTIVE Bony overgrowth and spontaneous fusion are complications of cervical arthroplasty. In contrast, bone loss or bone remodeling of vertebral bodies at the operation segment after cervical arthroplasty has also been observed. The purpose of this study is to investigate a potential complication-bone loss of the anterior portion of the vertebral bodies at the surgically treated segment after cervical total disc replacement (TDR)-and discuss the clinical significance. METHODS All enrolled patients underwent follow-up for more than 24 months after cervical arthroplasty using the Baguera C disc...
February 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28142245/cervical-arthroplasty-what-does-the-labeling-say
#10
REVIEW
Mazda K Turel, Mena G Kerolus, Owoicho Adogwa, Vincent C Traynelis
OBJECTIVE The aim of this paper was to comprehensively review each of the Food and Drug Administration (FDA)-approved labels of 7 total cervical disc replacements, assess the exact methodology in which the trial was conducted, and provide a broad comparison of these devices to allow each surgeon to determine which disc best suits his or her specific treatment goals based on the specific labels and not the studies published. METHODS The FDA-approved labels for each of the 7 artificial discs were obtained from the official FDA website...
February 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28042722/m6-c-artificial-disc-placement
#11
Domagoj Coric, John Parish, Margaret O Boltes
There has been a steady evolution of cervical total disc replacement (TDR) devices over the last decade resulting in surgical technique that closely mimics anterior cervical discectomy and fusion as well as disc design that emphasizes quality of motion. The M6-C TDR device is a modern-generation artificial disc composed of titanium endplates with tri-keel fixation as well as a polyethylene weave with a polyurethane core. Although not yet approved by the FDA, M6-C has finished a pilot and pivotal US Investigational Device Exemption (IDE) study...
January 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28042721/surgical-technique-for-revision-surgery-of-cervical-artificial-disc-replacements
#12
Julia Onken, Bernhard Meyer, Peter Vajkoczy
OBJECTIVE Cervical artificial disc replacement (C-ADR) is a widely used procedure with low risk at implantation. Few cases have been reported about the surgical techniques of C-ADR revision. The authors describe their surgical experience with the explantation of a Galileo C-ADR. METHODS Revision surgery was performed in a 58-year-old patient. Patient positioning and surgical opening techniques were performed as appropriate for anterior cervical decompression. RESULTS Revision surgery via the initial anterior approach was successful following an atraumatic removal of the implant...
January 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28032699/an-analysis-of-paravertebral-ossification-in-cervical-artificial-disc-replacement-a-novel-classification-based-on-computed-tomography
#13
Wei Tian, Ming-Xing Fan, Ya-Jun Liu, Xiao Han, Kai Yan, Han Wang, Yan-Wei Lyu
OBJECTIVE: Cervical artificial disc replacement (CADR) is a new technology in cervical spine surgery. However, CADR may result in paravertebral ossification (PO) after surgery and affect the mobility of the related spinal segments. The present widely used assessment method based on X-ray tomography cannot provide the position information of PO, and also PO detection rates by X-ray are low. The incidence of PO varies dramatically between studies. This study built a novel classification system based on cervical computer tomography (CT) scan to re-evaluate the incidence of PO and its influence on CADR, and also analyzed the predisposing factors of PO...
November 2016: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28002363/comparison-of-outcomes-of-single-level-anterior-cervical-discectomy-with-fusion-and-single-level-artificial-cervical-disc-replacement-for-single-level-cervical-degenerative-disc-disease
#14
Praveen Kumar Pandey, Inder Pawar, Jyoti Gupta, Raaghav Rai Verma
STUDY DESIGN: A single-center, prospective comparative study of prospectively collected outcomes, with a minimum 12 months follow-up. OBJECTIVES: The primary purpose of the study is to investigate the clinical, functional, and radiological outcomes of cervical total disc replacement (CTDR) in comparison with anterior cervical discectomy and fusion (ACDF) in the treatment of single-level cervical disc degenerative disease, prospectively. SUMMARY OF BACKGROUND DATA: CTDR has recently been an alternative to ACDF in cervical disc degenerative disease to preserve the motion at the treated level...
January 1, 2017: Spine
https://www.readbyqxmd.com/read/27939974/revision-surgeries-following-artificial-disc-replacement-of-cervical-spine
#15
Jong-Beom Park, Han Chang, Jin S Yeom, Kyung-Soo Suk, Dong-Ho Lee, Jae Chul Lee
OBJECTIVE: We investigated causes and results of revision surgeries after artificial disc replacement of cervical spine (C-ADR). METHODS: Twenty-one patients (mean age: 52.8) who underwent revision surgery after C-ADR and who had a minimum 2-year of follow-up were included into this study. The mean time between the primary and revision surgeries was 21 months. During their primary surgeries, 14 patients underwent single level C-ADR, 2 two-level C-ADR, and 5 two-level hybrid surgery for 16 radiculopathy, 3 myelopathy, and 2 adjacent segment diseases...
December 2016: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/27902945/artificial-cervical-disc-replacement-with-the-prestige-lp-prosthesis-for-the-treatment-of-non-contiguous-2-level-cervical-degenerative-disc-disease-a-minimum-24-month-follow-up
#16
Tingkui Wu, Beiyu Wang, Chen Ding, Yang Meng, Jigang Lou, Yi Yang, Hao Liu
OBJECTIVE: We describe the features of non-contiguous 2-level cervical degenerative disc disease (NCDDD), investigate the safety and feasibility of artificial cervical disc replacement (ACDR) for the treatment of NCDDD, and expect that our study will provide spine surgeons with an alternative procedure for NCDDD. METHODS: Twenty-five patients with NCDDD received ACDR with a Prestige-LP prosthesis. Clinical outcomes were evaluated using the 36-Short Form (SF-36, Mental Component Summary [MCS] and Physical Component Summary [PCS]), Visual Analog Scale (VAS), Japanese Orthopedic Association (JOA), and Neck Disability Index (NDI) scores...
January 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27890691/minimum-four-year-subsequent-surgery-rates-of-cervical-disc-replacement-versus-fusion-a-meta-analysis-of-prospective-randomized-clinical-trials
#17
T K Wu, H Liu, B Y Wang, Y Meng
INSTRUCTION: Anterior cervical discectomy and fusion (ACDF) is a well-accepted surgical management strategy for radiculopathy and/or myelopathy. However, complications sometimes required subsequent surgery at the operated and adjacent levels. Artificial cervical disc replacement (ACDR) has been accepted as the most extensive non-fusion procedure and is designed to preserve motion. However, some specific complications can result in subsequent surgery, thus, attracting the attention of investigators...
November 24, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27888676/revision-surgery-for-cervical-artificial-disc-surgical-technique-and-clinical-results
#18
J Onken, A Reinke, J Radke, T Finger, S Bayerl, P Vajkoczy, B Meyer
OBJECTIVE: Cervical artificial disc replacement (C-ADR) was developed with the goal of preserving mobility of the cervical segment in patients with degenerative disc disease. So far, little is known about experiences with revision surgery and explantation of C-ADRs. Here, we report our experience with revision the third generation, Galileo-type disc prosthesis from a retrospective study of two institutions. PATIENTS AND METHODS: Between November 2008 and July 2016, 16 patients with prior implantation of C-ADR underwent removal of the Galileo-type disc prosthesis (Signus, Medizintechnik, Germany) due to a call back by industry...
January 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27836574/towards-bioreactor-development-with-physiological-motion-control-and-its-applications
#19
Marcus Stoffel, Wolfgang Willenberg, Marzieh Azarnoosh, Nadine Fuhrmann-Nelles, Bei Zhou, Bernd Markert
In biomedical applications bioreactors are used, which are able to apply mechanical loadings under cultivation conditions on biological tissues. However, complex mechanobiological evolutions, such as the dependency between mechanical properties and cell activity, depend strongly on the applied loading conditions. This requires correct physiological movements and loadings in bioreactors. The aim of the present study is to develop bioreactors, in which native and artificial biological tissues can be cultivated under physiological conditions in knee joints and spinal motion segments...
January 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/27826089/ulf-fernstr%C3%A3-m-1915-1985-and-his-contributions-to-the-development-of-artificial-disc-replacements
#20
REVIEW
Christian Fisahn, Brittni Burgess, Joe Iwanaga, Jens R Chapman, Rod J Oskouian, R Shane Tubbs
INTRODUCTION: Artificial disc replacements, which serve the function of separating vertebrae to allow for proper spinal alignment, can help treat debilitating low back pain in patients who have failed other conservative methods of treatment. A Swedish surgeon, Ulf Fernström, was the pioneer of artificial disc replacement, and his contribution in the form of Fernström balls dramatically altered spinal surgery and technique by showing the proper technique and implant that should be used for areas requiring motion in many planes...
February 2017: World Neurosurgery
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