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https://www.readbyqxmd.com/read/28214234/reablement-reactivation-rehabilitation-and-restorative-interventions-with-older-adults-in-receipt-of-home-care-a-systematic-review
#1
REVIEW
Joanie Sims-Gould, Catherine E Tong, Lutetia Wallis-Mayer, Maureen C Ashe
OBJECTIVE: To systematically review the impact of reablement, reactivation, rehabilitation, and restorative (4R) programs for older adults in receipt of home care services. DESIGN: Systematic review. DATA SOURCES: We searched the following electronic bibliographic databases: MEDLINE, EMBASE, PsycINFO, CINAHL (Cumulative Index to Nursing and Allied Health), SPORTDiscus and The Cochrane Library and reference lists. STUDY SELECTION: Randomized controlled trials that describe original data on the impact of home-based rehabilitative care and were written in English...
February 14, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28213638/hung-out-to-dry-intraspecific-variation-in-water-loss-in-a-hibernating-bat
#2
Brandon J Klüg-Baerwald, R Mark Brigham
Hibernation is a period of water deficit for some small mammals, and humidity strongly influences hibernation patterns. Dry conditions reduce length of torpor bouts, stimulate arousals, and decrease overwinter survival. To mitigate these effects, many small mammals hibernate in near saturated (100% RH) conditions. However, big brown bats (Eptesicus fuscus) hibernate in a wider variety of conditions and tolerate lower humidity than most other bats. To assess arid tolerance in this species, we compared torpid metabolic rates (TMR) and rates of total evaporative water loss (TEWL) between two populations of E...
February 17, 2017: Oecologia
https://www.readbyqxmd.com/read/28211643/postural-analysis-in-a-pediatric-cohort-of-patients-with-ehlers-danlos-syndrome-a-pilot-study
#3
Claudio Lisi, Serena Monteleone, Carmine Tinelli, Berardo Rinaldi, Giuseppe Di Natali, Salvatore Savasta
BACKGROUND: The Ehlers-Danlos Syndrome (EDS) is a rare disorder affecting the connective tissue. EDS patients may suffer of proprioception and balance impairment but all the studies dealing with such symptoms have been addressed to adult subjects. The Study of such impairment in younger patients may lead to a better awareness of own motor abilities and to a focused rehabilitative intervention. Therefore, our work aims to assess the occurrence of these alterations in a pediatric cohort of EDS patients...
February 17, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/28210064/toe-functions-have-little-effect-on-dynamic-balance-ability-in-elderly-people
#4
Yoshinobu Yoshimoto, Yukitsuna Oyama, Mamoru Tanaka, Asuka Sakamoto
[Purpose] The purpose of this study was to examine the toe function of elderly people and the association with the dynamic balance ability for the developing effective fall-prevention measures. [Subjects and Methods] Seventy-eight participants in a community health service were included in this cross-sectional study. The Timed Up and Go Test and Four Square Step Test were used to test dynamic balance ability. The toe functions related to dynamic balance ability were toe flexion strength, presence or absence of restricted range of motion of the hallux, presence or absence of hallux pain, and hallux valgus angle...
January 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28210057/a-comparison-of-the-balance-and-gait-function-between-children-with-down-syndrome-and-typically-developing-children
#5
Hee-Kyoung Jung, EunJung Chung, Byoung-Hee Lee
[Purpose] The purpose of this study was to compare the balance and gait functions of children with Down syndrome and typically developing children according to age. [Subjects and Methods] The subjects were 16 children with Down syndrome and 20 children with typical development. The one leg standing test, Romberg's test (open eyes/closed eyes), sharpened Romberg's (open eyes/closed eyes), functional reaching test and GAITRite were used for this study in order to measure the children's balance and gait function...
January 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28210054/sagittal-plane-spinal-mobility-is-associated-with-dynamic-balance-ability-of-community-dwelling-elderly-people
#6
Yahiko Takeuchi
[Purpose] The purpose of this study was to clarify the correlation between the range of spinal mobility on the sagittal plane and the dynamic balance ability of elderly people living in communities. [Subjects and Methods] The persons studied were 31 healthy elderly people living in the community (16 females and 15 males). The range of mobility of the participants' spines in the sagittal plane was measured by using a spinal mouse(®). Balance ability was evaluated by using Functional reach (FR), Timed up and go (TUG), and Maximum walking speed (MWS)...
January 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28209702/primary-care-specialty-career-choice-among-canadian-medical-students-understanding-the-factors-that-influence-their-decisions
#7
Heather Ann Osborn, Jordan T Glicksman, Michael G Brandt, Philip C Doyle, Kevin Fung
OBJECTIVE: To identify which factors influence medical students' decision to choose a career in family medicine and pediatrics, and which factors influence their decision to choose careers in non-front-line specialties. DESIGN: Survey that was created based on a comprehensive literature review to determine which factors are considered important when choosing practice specialty. SETTING: Ontario medical school. PARTICIPANTS: An open cohort of medical students in the graduating classes of 2008 to 2011 (inclusive)...
February 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28208390/geometry-and-design-of-origami-bellows-with-tunable-response
#8
Austin Reid, Frederic Lechenault, Sergio Rica, Mokhtar Adda-Bedia
Origami folded cylinders (origami bellows) have found increasingly sophisticated applications in space flight and medicine. In spite of this interest, a general understanding of the mechanics of an origami folded cylinder has been elusive. With a newly developed set of geometrical tools, we have found an analytic solution for all possible cylindrical rigid-face states of both Miura-ori and triangular tessellations. Although an idealized bellows in both of these families may have two allowed rigid-face configurations over a well-defined region, the corresponding physical device, limited by nonzero material thickness and forced to balance hinge and plate-bending energy, often cannot stably maintain a stowed configuration...
January 2017: Physical Review. E
https://www.readbyqxmd.com/read/28203231/error-prone-dnae2-balances-the-genome-mutation-rates-in-myxococcus-xanthus-dk1622
#9
Ran Peng, Jiang-He Chen, Wan-Wan Feng, Zheng Zhang, Jun Yin, Ze-Shuo Li, Yue-Zhong Li
dnaE is an alpha subunit of the tripartite protein complex of DNA polymerase III that is responsible for the replication of bacterial genome. The dnaE gene is often duplicated in many bacteria, and the duplicated dnaE gene was reported dispensable for cell survivals and error-prone in DNA replication in a mystery. In this study, we found that all sequenced myxobacterial genomes possessed two dnaE genes. The duplicate dnaE genes were both highly conserved but evolved divergently, suggesting their importance in myxobacteria...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28203208/changes-in-heart-rate-variability-recorded-in-natural-situation-with-t-shirt-integrated-sensors-and-level-of-observed-behavioral-excitation-a-pilot-study-of-patients-with-intellectual-disabilities-and-psychiatric-disorders
#10
Julie Palix, Michel Akselrod, Charly Cungi, Fabienne Giuliani, Jérôme Favrod
BACKGROUND: The present study investigates the possibilities of using heart rate variability (HRV) parameters as physiological markers that precede increase in observed behavioral excitation of intellectually disabled individuals. The ability to recognize or predict such patterns, especially in patients showing unpredictable reactions and language deficiencies, might be a major step forward in clinical research. METHOD: Thirteen volunteers with intellectual disabilities, who had suffered of at least one event of overt aggression in the preceding 3 months, participated to the study...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28202540/sorting-out-adipocyte-precursors-and-their-role-in-physiology-and-disease
#11
REVIEW
Chelsea Hepler, Lavanya Vishvanath, Rana K Gupta
The ability to maintain and expand the pool of adipocytes in adults is integral to the regulation of energy balance, tissue/stem cell homeostasis, and disease pathogenesis. For decades, our knowledge of adipocyte precursors has relied on cellular models. The identity of native adipocyte precursors has remained unclear. Recent studies have identified distinct adipocyte precursor populations that are physiologically regulated and contribute to the development, maintenance, and expansion of adipocyte pools in mice...
January 15, 2017: Genes & Development
https://www.readbyqxmd.com/read/28202042/hoxc8-regulates-self-renewal-differentiation-and-transformation-of-breast-cancer-stem-cells
#12
Mansi Shah, Ryan Cardenas, Belinda Wang, Jenny Persson, Nigel P Mongan, Anna Grabowska, Cinzia Allegrucci
BACKGROUND: Homeobox genes are master regulators of cell fate during embryonic development and their expression is altered in cancer. By regulating the balance between cell proliferation and differentiation, they maintain homeostasis of normal tissues. Here, we screened the expression of homeobox genes in mammary stem cells to establish their role in stem cells transformation in breast cancer. METHODS: Using a Homeobox Genes PCR array, we screened 83 homeobox genes in normal cancer breast stem/progenitor cells isolated by flow cytometry...
February 16, 2017: Molecular Cancer
https://www.readbyqxmd.com/read/28199741/melatonin-prevents-obesity-through-modulation-of-gut-microbiota-in-mice
#13
Pengfei Xu, Jialin Wang, Fan Hong, Sheng Wang, Xi Jin, Tingting Xue, Li Jia, Yonggong Zhai
Excess weight and obesity are severe public health threats worldwide. Recent evidence demonstrates that gut microbiota dysbiosis contributes to obesity and its comorbidities. The body weight-reducing and energy balancing effects of melatonin have been reported in several studies, but to date, no investigations toward examining whether the beneficial effects of melatonin are associated with gut microbiota have been carried out. In this study, we show that melatonin reduces body weight, liver steatosis, and low-grade inflammation as well as improving insulin resistance in high fat diet (HFD)-fed mice...
February 15, 2017: Journal of Pineal Research
https://www.readbyqxmd.com/read/28197758/blocking-effects-in-non-conditioned-goal-directed-behaviour
#14
Ann-Kathrin Stock, Krutika Gohil, Christian Beste
A great deal of our goal-directed behaviour depends on stimulus-response (S-R) associations, which can be established through conditioning or explicit instructions. For conditioned and reward maximizing behaviour, it has been shown that redundant information will no longer be taken into account once those associations have been formed ("blocking effect"). Following from this, new aspects will not be included in a pre-established association unless they improve behaviour. Opposing this, influential action control theories state that all kinds of information may be taken into account during action selection, thus denying the possibility of blocking redundant "surplus" information from non-conditioned goal-directed behaviour...
February 14, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28197085/anodal-transcranial-direct-current-stimulation-does-not-facilitate-dynamic-balance-task-learning-in-healthy-old-adults
#15
Elisabeth Kaminski, Maike Hoff, Viola Rjosk, Christopher J Steele, Christopher Gundlach, Bernhard Sehm, Arno Villringer, Patrick Ragert
Older adults frequently experience a decrease in balance control that leads to increased numbers of falls, injuries and hospitalization. Therefore, evaluating older adults' ability to maintain balance and examining new approaches to counteract age-related decline in balance control is of great importance for fall prevention and healthy aging. Non-invasive brain stimulation techniques such as transcranial direct current stimulation (tDCS) have been shown to beneficially influence motor behavior and motor learning...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28195684/extended-rf-shimming-sequence-level-parallel-transmission-optimization-applied-to-steady-state-free-precession-mri-of-the-heart
#16
Arian Beqiri, Anthony N Price, Francesco Padormo, Joseph V Hajnal, Shaihan J Malik
Cardiac magnetic resonance imaging (MRI) at high field presents challenges because of the high specific absorption rate and significant transmit field (B1(+) ) inhomogeneities. Parallel transmission MRI offers the ability to correct for both issues at the level of individual radiofrequency (RF) pulses, but must operate within strict hardware and safety constraints. The constraints are themselves affected by sequence parameters, such as the RF pulse duration and TR, meaning that an overall optimal operating point exists for a given sequence...
February 14, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28195607/effects-of-cementing-on-ligament-balance-during-total-knee-arthroplasty
#17
Jimmy Chow, Kevin Wang, Leah Elson, Christopher Anderson, Martin Roche
Complications related to joint imbalance may contribute to some of the most predominant modes of failure in total knee arthroplasty (TKA). These complications include instability, aseptic loosening, asymmetric component wear, and idiopathic pain. Fixation may represent a step that introduces unchecked variability into the procedure and may contribute to the incidence of joint imbalance-related complications. The ability to quantify in vivo loading in the medial and lateral compartments would allow for the ability to confirm balance after fixation and prior to wound closure...
February 13, 2017: Orthopedics
https://www.readbyqxmd.com/read/28194230/what-are-the-personal-and-professional-characteristics-that-distinguish-the-researchers-who-publish-in-high-and-low-impact-journals-a-multi-national-web-based-survey
#18
Carlos Eduardo Paiva, Raphael L C Araujo, Bianca Sakamoto Ribeiro Paiva, Cristiano de Pádua Souza, Flavio Mavignier Cárcano, Marina Moreira Costa, Sérgio Vicente Serrano, João Paulo Nogueira Lima
PURPOSE: This study identifies the personal and professional profiles of researchers with a greater potential to publish high-impact academic articles. METHOD: The study involved conducting an international survey of journal authors using a web-based questionnaire. The survey examined personal characteristics, funding, and the perceived barriers of research quality, work-life balance, and satisfaction and motivation in relation to career. The processes of manuscript writing and journal publication were measured using an online questionnaire that was developed for this study...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28194100/head-stability-and-head-trunk-coordination-in-horseback-riders-the-contribution-of-visual-information-according-to-expertise
#19
Agnès Olivier, Elise Faugloire, Laure Lejeune, Sophie Biau, Brice Isableu
Maintaining equilibrium while riding a horse is a challenging task that involves complex sensorimotor processes. We evaluated the relative contribution of visual information (static or dynamic) to horseback riders' postural stability (measured from the variability of segment position in space) and the coordination modes they adopted to regulate balance according to their level of expertise. Riders' perceptual typologies and their possible relation to postural stability were also assessed. Our main assumption was that the contribution of visual information to postural control would be reduced among expert riders in favor of vestibular and somesthetic reliance...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28190729/a-functional-gradient-in-the-rodent-prefrontal-cortex-supports-behavioral-inhibition
#20
Stefanie Hardung, Robert Epple, Zoe Jäckel, David Eriksson, Cem Uran, Verena Senn, Lihi Gibor, Ofer Yizhar, Ilka Diester
The ability to plan and execute appropriately timed responses to external stimuli is based on a well-orchestrated balance between movement initiation and inhibition. In impulse control disorders involving the prefrontal cortex (PFC) [1], this balance is disturbed, emphasizing the critical role that PFC plays in appropriately timing actions [2-4]. Here, we employed optogenetic and electrophysiological techniques to systematically analyze the functional role of five key subareas of the rat medial PFC (mPFC) and orbitofrontal cortex (OFC) in action control [5-9]...
February 7, 2017: Current Biology: CB
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