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Prolonged pregnancy

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https://www.readbyqxmd.com/read/28333939/maintenance-nifedipine-therapy-for-preterm-symptomatic-placenta-previa-a-randomized-multicenter-double-blind-placebo-controlled-trial
#1
Eric Verspyck, Claire de Vienne, Charles Muszynski, Michael Bubenheim, Isabella Chanavaz-Lacheray, Michel Dreyfus, Philippe Deruelle, Jacques Benichou
OBJECTIVE: To assess the impact of maintenance nifedipine therapy on pregnancy duration in women with preterm placenta previa bleeding. METHODS: PPADAL was a randomized, double-blind, placebo-controlled trial conducted between 05/2008 and 05/2012 in five French hospitals. The trial included 109 women, aged ≥ 18 years, with at least one episode of placenta previa bleeding, intact membranes and no other pregnancy complication, at gestational age 24 to 34 weeks and after 48 hours of complete acute tocolysis...
2017: PloS One
https://www.readbyqxmd.com/read/28329577/two-cases-of-halo-scalp-ring
#2
Thaer Hasan Douri
Halo scalp ring (HSR) is a rare form of non-scarring annular alopecia that is attributed to caput succedaneum. It arises perinatally because of prolonged pressure on the scalp by the cervix during or before the delivery. We report two new cases of halo scalp ring in full term pregnancy - newborns.
November 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28328031/post-traumatic-stress-disorder-and-antepartum-complications-a-novel-risk-factor-for-gestational-diabetes-and-preeclampsia
#3
Jonathan G Shaw, Steven M Asch, Jodie G Katon, Kate A Shaw, Rachel Kimerling, Susan M Frayne, Ciaran S Phibbs
BACKGROUND: Prior work shows that Post-traumatic Stress Disorder (PTSD) predicts an increased risk of preterm birth, but the causal pathway(s) are uncertain. We evaluate the associations between PTSD and antepartum complications to explore how PTSD's pathophysiology impacts pregnancy. METHODS: This retrospective cohort analysis of all Veterans Health Administration (VA)-covered deliveries from 2000-12 used the data of VA clinical and administration. Mothers with current PTSD were identified using the ICD-9 diagnostic codes (i...
March 22, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28324223/adverse-neonatal-and-maternal-outcome-following-vacuum-assisted-vaginal-delivery-does-indication-matter
#4
Lina Salman, Amir Aviram, Eyal Krispin, Arnon Wiznitzer, Rony Chen, Rinat Gabbay-Benziv
PURPOSE: To estimate the impact of indication for vacuum-assisted vaginal delivery on neonatal and maternal adverse outcome. METHODS: Retrospective analysis of women carrying singleton-term pregnancies undergoing vacuum-assisted vaginal delivery in a tertiary hospital (2007-2014). Cohort was stratified by indication: non-reassuring fetal heart rate or prolonged second stage. Primary outcome was adverse neonatal outcome and secondary outcome was maternal morbidity...
March 21, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28320595/brain-death-during-pregnancy-and-prolonged-corporeal-support-of-the-body-a-critical-discussion
#5
Lynne Staff, Meredith Nash
AIM: To discuss corporeal support of the brain-dead pregnant woman and to critically examine important aspects of this complex situation that remain as yet unexplored. BACKGROUND: When brain death of the woman occurs during pregnancy, the fetus may be kept inside the corporeally supported body for prolonged periods to enable continued fetal growth and development. This has been increasingly reported in medical literature since 1982 and has received considerable media attention in the past few years...
March 17, 2017: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/28319314/progesterone-to-prevent-preterm-birth-the-studies-are-getting-better-but-there-is-still-room-for-improvement
#6
Carr Men Chung, Maud van Zijl, Jeffrey A Keelan, Ben Willem Mol
Spontaneous preterm birth (PTB) remains one of the pressing problems of modern obstetrics. Allen and Corner first isolated progesterone and proposed the name because of its pro-gestational activity (Allen 1930). Progesterone prolongs pregnancy via a range of actions in the myometrium, cervix and placenta which, when exploited pharmacologically, might delay or even prevent PTB. This article is protected by copyright. All rights reserved.
March 20, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28302175/prolonged-hypothyroidism-severely-reduces-ovarian-follicular-reserve-in-adult-rats
#7
Li Meng, Eddy Rijntjes, Hans J M Swarts, Jaap Keijer, Katja J Teerds
BACKGROUND: There is substantial evidence both in humans and in animals that a prolonged reduction in plasma thyroid hormone concentration leads to reproductive problems, including disturbed folliculogenesis, impaired ovulation and fertilization rates, miscarriage and pregnancy complications. The objective of the present study is to examine the consequences of chronic hypothyroidism, induced in adulthood, for the size of the ovarian follicle pool. In order to investigate this, adult female rats were provided either a control or an iodide deficient diet in combination with perchlorate supplementation to inhibit iodide uptake by the thyroid...
March 16, 2017: Journal of Ovarian Research
https://www.readbyqxmd.com/read/28296762/effect-on-mother-and-child-of-eculizumab-given-before-caesarean-section-in-a-patient-with-severe-antiphospholipid-syndrome-a-case-report
#8
Alice Gustavsen, Lillemor Skattum, Grethe Bergseth, Bjorg Lorentzen, Yngvar Floisand, Vidar Bosnes, Tom Eirik Mollnes, Andreas Barratt-Due
RATIONALE: Antiphospholipid syndrome (APS) in pregnancy may trigger the life-threatening catastrophic antiphospholipid syndrome (CAPS). Complement activation is implicated in the pathogenesis, and inhibition of complement factor C5 is suggested as an additional treatment option. PATIENT CONCERNS, DIAGNOSIS AND INTERVENTIONS: We present a pregnant patient treated with the C5-inhibitor eculizumab due to high risk of developing devastating APS-related complications...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28292451/long-acting-reversible-contraception-an-essential-guide-for-pediatric-primary-care-providers
#9
REVIEW
Suzanne Allen, Erin Barlow
Long-acting reversible contraception (LARC) methods are 20% more effective than traditional contraceptives and are recommended by the American Academy of Pediatrics and American College of Obstetrics and Gynecology as first-line contraception for adolescent girls. Large studies show that LARC use reduces unintended pregnancies, increases user satisfaction, and prolongs duration of use. This article prepares the primary care provider (PCP) with knowledge on safety, efficacy, eligibility, confidentiality, anticipatory guidance, how to find a LARC provider, and guidance on common side effects so the PCP can confidently counsel adolescent patients on LARC methods...
April 2017: Pediatric Clinics of North America
https://www.readbyqxmd.com/read/28283728/survey-of-gadolinium-based-contrast-agent-utilization-among-the-members-of-the-society-for-pediatric-radiology-a-quality-and-safety-committee-report
#10
Einat Blumfield, Michael M Moore, Mary K Drake, Thomas R Goodman, Kristopher N Lewis, Laura T Meyer, Thang D Ngo, Christina Sammet, Arta Luana Stanescu, David W Swenson, Thomas L Slovis, Ramesh S Iyer
BACKGROUND: Gadolinium-based contrast agents (GBCAs) have been used for magnetic resonance (MR) imaging over the last three decades. Recent reports demonstrated gadolinium retention in patients' brains following intravenous administration. Since gadolinium is a highly toxic heavy metal, there is a potential for adverse effects from prolonged retention or deposition, particularly in children. For this reason, the Society (SPR) for Pediatric Radiology Quality and Safety committee conducted a survey to evaluate the current status of GBCAs usage among pediatric radiologists...
March 10, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28279213/cardiovascular-risk-factors-are-major-determinants-of-thrombotic-risk-in-patients-with-the-lupus-anticoagulant
#11
Florian Posch, Johanna Gebhart, Jacob H Rand, Silvia Koder, Peter Quehenberger, Vittorio Pengo, Cihan Ay, Ingrid Pabinger
BACKGROUND: Patients with the lupus anticoagulant (LA) are at an increased risk of thrombotic events, which in turn increase the risk of death. Understanding the determinants of thrombotic risk in patients with LA may pave the way towards targeted thromboprophylaxis. In the Vienna Lupus Anticoagulant and Thrombosis Study (LATS), we systematically evaluate risk factors for thrombotic events in patients with LA. METHODS: We followed 150 patients (mean age: 41.3 years, female gender: n = 122 (81...
March 10, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28278012/reproductive-health-rights-and-survival-the-voices-of-mothers-experiencing-homelessness
#12
Courtney Cronley, Kris Hohn, Shamsun Nahar
Women experiencing homelessness report higher rates of reproductive health-related traumas, including unplanned pregnancy, miscarriage, and abortion than their non-homeless peers. Using phenomenological hermeneutic methods, we sought to understand the reproductive health histories of women currently experiencing homelessness (N = 20, 25-61 years old, Mage = 38.33, SDage = 9.33) analyzing data collected between June 2014 and July 2015 in north central Texas. Three key themes highlight the essence of the women's experiences: (1) unexpected pregnancy-pregnancy just happened, (2) loss of reproductive health rights-I was broken, and (3) resilience-giving back and looking forward to good things...
February 16, 2017: Women & Health
https://www.readbyqxmd.com/read/28277366/association-of-maternal-obesity-with-maternal-and-neonatal-outcomes-in-cases-of-uterine-rupture
#13
Ruofan Yao, Katherine R Goetzinger, Sarah D Crimmins, Jerome N Kopelman, Stephen A Contag
OBJECTIVE: To describe the risk of adverse outcomes associated with uterine rupture in the setting of maternal obesity. METHODS: This was a retrospective cohort analysis of singleton nonanomalous neonates born after uterine rupture between 34 and 42 weeks of gestation. We derived data from the U.S. Natality Database from 2011 to 2014. Maternal prepregnancy body mass index (BMI) was categorized according to the World Health Organization classification. The rates of neonatal and maternal complications were calculated for each BMI class...
April 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28277352/sildenafil-citrate-therapy-for-oligohydramnios-a-randomized-controlled-trial
#14
Mohammad Ahmed Maher, Tarek Mohammad Sayyed, Nabih Elkhouly
OBJECTIVE: To compare sildenafil plus hydration with hydration alone in improving the amniotic fluid index and neonatal outcomes in pregnancies complicated by idiopathic oligohydramnios ( amniotic fluid index less than 5 cm without underlying maternal or fetal causes and with normal fetal growth). METHODS: This was an open-label randomized trial for women carrying singleton pregnancies at 30 weeks of gestation or more with idiopathic oligohydramnios detected during routine ultrasonogram...
April 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28271028/sedentary-behavior-patterns-in-non-pregnant-and-pregnant-women
#15
Marquis Hawkins, Youngdeok Kim, Kelley Pettee Gabriel, Bonny Jane Rockette-Wagner, Lisa Chasan-Taber
Sedentary behavior has been associated with adverse health outcomes among pregnant women; however, few studies have characterized sedentary behavior patterns in this population. We described patterns of accelerometer-determined indicators of sedentary behavior among a national sample of US pregnant (n = 234) women and non-pregnant (n = 1146) women participating in the NHANES 2003-06 cycles. We included women with ≥ 4 days of accelerometer wear of ≥ 10 h/day. A count threshold of < 100 cpm was used to describe sedentary behavior as: 1) total accumulated sedentary time by bout length categories; 2) accumulated sedentary time within discrete bout length categories; 3) mean, median, and usual bout length; and 4) and bout frequency...
June 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/28267223/fundal-pressure-during-the-second-stage-of-labour
#16
REVIEW
G Justus Hofmeyr, Joshua P Vogel, Anna Cuthbert, Mandisa Singata
BACKGROUND: Fundal pressure during the second stage of labour (also known as the 'Kristeller manoeuvre') involves application of manual pressure to the uppermost part of the uterus directed towards the birth canal, in an attempt to assist spontaneous vaginal birth and avoid prolonged second stage or the need for operative birth. Fundal pressure has also been applied using an inflatable belt. Fundal pressure is widely used, however methods of its use vary widely. Despite strongly held opinions in favour of and against the use of fundal pressure, there is limited evidence regarding its maternal and neonatal benefits and harms...
March 7, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28262917/bed-rest-with-and-without-hospitalisation-in-multiple-pregnancy-for-improving-perinatal-outcomes
#17
REVIEW
Katharina da Silva Lopes, Yo Takemoto, Erika Ota, Shinji Tanigaki, Rintaro Mori
BACKGROUND: Strict or partial bed rest in hospital or at home is commonly recommended for women with multiple pregnancy to improve pregnancy outcomes. In order to advise women to rest in bed for any length of time, a policy for clinical practice needs to be supported by reliable evidence and weighed against possible adverse effects resulting from prolonged activity restriction. OBJECTIVES: The objective of this review is to assess the effectiveness of bed rest in hospital or at home to improve perinatal outcomes in women with a multiple pregnancy...
March 6, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28254221/progesterone-estradiol-ratio-0-25-on-the-day-of-human-chorionic-gonadotropin-administration-is-associated-with-adverse-pregnancy-outcomes-in-prolonged-protocols-for-in%C3%A2-vitro-fertilization-intracytoplasmic-sperm-injection
#18
Yuan Li, Keli Luo, Yi Tang, Ge Lin, Guangxiu Lu, Fei Gong
OBJECTIVE: It has been suggested that a progesterone/estradiol ratio (P/E2) ≥ 1.0 on the day of human chorionic gonadotropin (hCG) administration indicates premature luteinization and might be associated with an adverse pregnancy; however, a lower limit of this ratio has not been determined. We aimed to identify a lower limit of P/E2 that correlates significantly with an increase in adverse pregnancies in patients undergoing a prolonged in vitro fertilization/intracytoplasmic sperm injection therapy...
February 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28252630/-pharmacoepidemiological-study-of-the-course-of-influenza-and-other-acute-respiratory-viral-infections-in-risk-groups
#19
V A Bulgakova, A A Poromov, A I Grekova, N Yu Pshenichnaya, E P Selkova, N I Lvov, I A Leneva, I V Shestakova, V V Maleev
AIM: To identify risk factors (RFs) for the development of bacterial complications and the prolonged course of influenza and other acute respiratory viral infections (ARVIs) among inpatients treated in Russian healthcare facilities in the post-pandemic period; to determine the clinical presentation of the disease (flu-like syndrome) in risk-group people and to evaluate the efficacy of antiviral therapy with arbidol (umifenovir). MATERIAL AND METHODS: The investigators retrospectively analyzed randomly selected medical records of inpatients with influenza and other ARVI in 88 hospitals from 50 regions of the Russian Federation: those of 3532 and 1755 patients in the 2010-2011 and 2014-2015 seasons, respectively, by applying parametric and nonparametric statistical methods...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28251113/rh-isoimmunized-pregnancy-managed-noninvasively-a-report-of-two-cases
#20
Deepti Jain
Pregnancy with Rh isoimmunization is a grave situation. Two women with indirect Coombs test (ICT) positive were managed conservatively with a favorable outcome. Peak systolic velocity (PSV) of middle cerebral artery (MCA) was measured every 2 weeks, and pregnancy continued till the value remained <1.5 mean of median. In one woman, the pregnancy could be prolonged to 37 weeks when delivery was induced and the neonate did not develop hyperbilirubinemia. In the second woman with bad obstetric history, when a highly positive ICT was reported, intravenous immunoglobulin (IVIG) was given in a single dose of 5 g every 2 weeks starting at 27 weeks, for a total of three doses, along with measurement of PSV of MCA...
January 2017: International Journal of Applied and Basic Medical Research
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