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PTSD, Acute Stress Disorder

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https://www.readbyqxmd.com/read/28915145/posttraumatic-stress-disorder-symptoms-among-trauma-exposed-inpatient-adolescents-the-role-of-emotional-nonacceptance-and-anxiety-symptom-severity
#1
Andres G Viana, Abigail E Hanna, Elizabeth M Raines, Emma C Woodward, Daniel J Paulus, Erin C Berenz, Michael J Zvolensky
The present investigation examined the role of anxiety symptom severity in the relation between emotional nonacceptance and posttraumatic stress disorder (PTSD) symptoms in a diverse sample of trauma-exposed adolescents admitted for acute psychiatric care at an inpatient state hospital (N = 50; 52.0% women; 44% white; mean [SD] age, 15.1 [0.51] years; range, 12-17 years). Anxiety symptom severity partially accounted for the association between emotional nonacceptance and PTSD total symptoms, and fully accounted for the association between emotional nonacceptance and PTSD symptom cluster severity, even after controlling for covariates...
September 14, 2017: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/28913926/dangers-on-the-road-a-longitudinal-examination-of-passenger-initiated-violence-against-bus-drivers
#2
Biru Zhou, Richard Boyer, Stéphane Guay
This study examined the impact of workplace violence against 109 bus drivers over a 1-year span. Workplace violence is related to both psychological and work-related consequences. Our findings showed that bus drivers experienced a wide range of violence at work and the psychological consequences were devastating: Half of the participants met the diagnostic criteria for acute stress disorder within the first month following the index event. Majority of them experienced at least moderate levels of post-traumatic stress disorder (PTSD) problems over the 1-year span...
September 15, 2017: Stress and Health: Journal of the International Society for the Investigation of Stress
https://www.readbyqxmd.com/read/28895451/risk-factors-for-mild-traumatic-brain-injury-and-subsequent-post-traumatic-stress-disorder-and-mental-health-disorders-among-us-army-soldiers
#3
Dennis Edward Scofield, Susan P Proctor, Joseph R Kardouni, Owen T Hill, Craig J McKinnon
To determine the association of mild traumatic brain injury (mTBI) with subsequent Post-traumatic Stress Disorder (PTSD) and mental health disorders (MHD) and the intervening role of Acute Stress Disorder (ASD). This matched case-control study utilized the Total Army Injury and Health Outcomes Database (TAIHOD) to analyze Soldiers' (N=1,261,297) medical encounter data between 2002 and 2011. International Classification of Diseases, Ninth Revision (ICD-9) codes were used to identify: mTBI (following CDC surveillance definition for mTBI), MHD (ICD-9 codes for depression and anxiety, excluding PTSD), PTSD (ICD-9 309...
September 12, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28865495/repetitive-transcranial-magnetic-stimulation-rtms-for-treatment-resistant-major-depression-trmd-veteran-patients-study-protocol-for-a-randomized-controlled-trial
#4
Zhibao Mi, Kousick Biswas, J Kaci Fairchild, Anne Davis-Karim, Ciaran S Phibbs, Steven D Forman, Michael Thase, Gerald Georgette, Tamara Beale, David Pittman, Margaret Windy McNerney, Allyson Rosen, Grant D Huang, Mark George, Art Noda, Jerome A Yesavage
BACKGROUND: Evaluation of repetitive transcranial magnetic stimulation (rTMS) for treatment-resistant major depression (TRMD) in Veterans offers unique clinical trial challenges. Here we describe a randomized, double-blinded, intent-to-treat, two-arm, superiority parallel design, a multicenter study funded by the Cooperative Studies Program (CSP No. 556) of the US Department of Veterans Affairs. METHODS: We recruited medical providers with clinical expertise in treating TRMD at nine Veterans Affairs (VA) medical centers as the trial local investigators...
September 2, 2017: Trials
https://www.readbyqxmd.com/read/28838093/sex-differences-in-post-traumatic-stress-disorder-in-cardiovascular-patients-after-the-great-east-japan-earthquake-a-report-from-the-chart-2-study
#5
Takeo Onose, Yasuhiko Sakata, Kotaro Nochioka, Masanobu Miura, Takeshi Yamauchi, Kanako Tsuji, Ruri Abe, Takuya Oikawa, Shintaro Kasahara, Masayuki Sato, Takashi Shiroto, Satoshi Miyata, Jun Takahashi, Hiroaki Shimokawa
Aims: The temporal changes and sex differences in post-traumatic stress disorder (PTSD) after natural disasters remain unclear. Therefore, we examined the prevalence, prognostic impacts, and determinant factors of PTSD after the Great East Japan Earthquake (GEJE) of 11 March 2011 in cardiovascular (CV) patients registered in the Chronic Heart Failure Analysis and Registry in the Tohoku District (CHART)-2 Study (n = 10 219), with a special reference to sex. Methods and results: By self-completion questionnaires of the Japanese-language version of the Impact of Event Scale-Revised (IES-R-J), the prevalence of PTSD, defined as IES-R-J score ≥25, was 14...
July 1, 2017: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/28837948/coping-strategies-as-mediators-in-relation-to-resilience-and-posttraumatic-stress-disorder
#6
Nicholas J Thompson, Devika Fiorillo, Barbara O Rothbaum, Kerry J Ressler, Vasiliki Michopoulos
BACKGROUND: Resilience has been shown to protect against the development of posttraumatic stress disorder (PTSD) in the aftermath of trauma. However, it remains unclear how coping strategies influence resilience and PTSD development in the acute aftermath of trauma. The current prospective, longitudinal study investigated the relationship between resilience, coping strategies, and the development of chronic PTSD symptoms. METHODS: A sample of patients was recruited from an emergency department following a Criterion A trauma...
August 16, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28837111/longitudinal-impact-of-hurricane-sandy-exposure-on-mental-health-symptoms
#7
Rebecca M Schwartz, Christina N Gillezeau, Bian Liu, Wil Lieberman-Cribbin, Emanuela Taioli
Hurricane Sandy hit the eastern coast of the United States in October 2012, causing billions of dollars in damage and acute physical and mental health problems. The long-term mental health consequences of the storm and their predictors have not been studied. New York City and Long Island residents completed questionnaires regarding their initial Hurricane Sandy exposure and mental health symptoms at baseline and 1 year later (N = 130). There were statistically significant decreases in anxiety scores (mean difference = -0...
August 24, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28821498/impact-of-child-death-on-paediatric-trainees
#8
Clare E Hollingsworth, Carla Wesley, Jaymie Huckridge, Gabrielle M Finn, Michael J Griksaitis
OBJECTIVE: To assess the prevalence of symptoms of acute stress reactions (ASR) and post-traumatic stress disorder (PTSD) in paediatric trainees following their involvement in child death. DESIGN: A survey designed to identify trainees' previous experiences of child death combined with questions to identify features of PTSD. Quantitative interpretation was used alongside a χ(2) test. A p value of <0.05 was considered significant. SETTING: 604 surveys were distributed across 13 UK health education deaneries...
August 18, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28814465/the-ventromedial-prefrontal-cortex-in-a-model-of-traumatic-stress-fear-inhibition-or-contextual-processing
#9
Zachary T Pennington, Austin S Anderson, Michael S Fanselow
The ventromedial prefrontal cortex (vmPFC) has consistently appeared altered in post-traumatic stress disorder (PTSD). Although the vmPFC is thought to support the extinction of learned fear responses, several findings support a broader role for this structure in the regulation of fear. To further characterize the relationship between vmPFC dysfunction and responses to traumatic stress, we examined the effects of pretraining vmPFC lesions on trauma reactivity and enhanced fear learning in a rodent model of PTSD...
September 2017: Learning & Memory
https://www.readbyqxmd.com/read/28813311/acute-stress-disorder
#10
REVIEW
Richard A Bryant
Acute stress disorder (ASD) was introduced in DSM-IV to describe posttraumatic stress disorder (PTSD) symptoms that (a) occur in the initial month after trauma and (b) predict subsequent PTSD. Longitudinal studies have shown that most people who develop PTSD do not initially meet ASD criteria, which led to the decision in DSM-5 to limit the ASD diagnosis to describing acute stress reactions without any predictive function. Controlled trials have shown that trauma-focused cognitive behavior therapy is the treatment of choice for ASD, and is superior to pharmacological interventions...
April 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28807706/the-relationship-between-psychological-symptoms-and-ventricular-assist-device-implantation
#11
Himali Weerahandi, Nathan Goldstein, Laura P Gelfman, Ulrich Jorde, James N Kirkpatrick, Edith Meyerson, Judith Marble, Yoshifumi Naka, Sean Pinney, Mark S Slaughter, Emilia Bagiella, Deborah D Ascheim
CONTEXT: Ventricular assist devices (VADs) improve quality of life in advanced heart failure (HF) patients, but there are little data exploring psychological symptoms in this population. OBJECTIVE: This study examined the prevalence of psychiatric symptoms and disease over time in VAD patients. METHODS: This prospective multicenter cohort study enrolled patients immediately before or after VAD implant and followed them up to forty-eight weeks...
August 11, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28752417/metformin-alleviated-the-neuronal-oxidative-stress-in-hippocampus-of-rats-under-single-prolonged-stress
#12
Jiangang Wang, Bing Xiao, Fang Han, Yuxiu Shi
In an animal model of post-traumatic stress disorder (PTSD), our previous studies showed mitochondrial stress-induced apoptosis in the hippocampus. Metformin, the most commonly prescribed anti-diabetic drug, exerts its effects through 5'-adenosine monophosphate-activated protein kinase (AMPK) activation. It was shown that a neuroprotective role was gradually established against stroke, spinal cord injury and Parkinson's disease. The aim of this study was to explore the role of the AMPK pathway in neuronal apoptosis in the hippocampus using a rat model of PTSD...
July 27, 2017: Journal of Molecular Neuroscience: MN
https://www.readbyqxmd.com/read/28743198/do-acute-benefits-of-interpersonal-psychotherapy-for-posttraumatic-stress-disorder-endure
#13
John C Markowitz, Tse-Hwei Choo, Yuval Neria
OBJECTIVE: The Psychotherapies for Chronic PTSD randomised trial found that three 14-week psychotherapies acutely benefitted patients with chronic posttraumatic stress disorder (PTSD). Previous research has reported sustained follow-up benefits for prolonged exposure (PE) and relaxation therapy (RT), but few comparable data exist for interpersonal psychotherapy (IPT). We describe 3-month follow-up for acute responders to all 3 treatments. METHOD: Acute responders, defined a priori as ≥30% improved from baseline, were reevaluated after 3-month no-treatment follow-up by independent evaluators using the Clinician-Administered PTSD Scale (CAPS)...
January 1, 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/28741031/inhibition-of-serotonin-transporters-disrupts-the-enhancement-of-fear-memory-extinction-by-3-4-methylenedioxymethamphetamine-mdma
#14
Matthew B Young, Seth D Norrholm, Lara M Khoury, Tanja Jovanovic, Sheila A M Rauch, Collin M Reiff, Boadie W Dunlop, Barbara O Rothbaum, Leonard L Howell
RATIONALE: 3,4-Methylenedioxymethamphetamine (MDMA) persistently improves symptoms of post-traumatic stress disorder (PTSD) when combined with psychotherapy. Studies in rodents suggest that these effects can be attributed to enhancement of fear memory extinction. Therefore, MDMA may improve the effects of exposure-based therapy for PTSD, particularly in treatment-resistant patients. However, given MDMA's broad pharmacological profile, further investigation is warranted before moving to a complex clinical population...
July 24, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28682981/risk-factors-of-delayed-onset-posttraumatic-stress-disorder-in-chronically-critically-ill-patients
#15
Gloria-Beatrice Wintermann, Jenny Rosendahl, Kerstin Weidner, Bernhard Strauß, Katja Petrowski
The main aim of this study was to investigate factors associated with a delayed-onset posttraumatic stress disorder (PTSD) after the intensive care unit (ICU) treatment of patients with a chronic critical illness (CCI). Patients (n = 97) with critical illness polyneuropathy or critical illness myopathy were interviewed via the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, 4th Edition. The diagnosis of the acute stress disorder was assessed within 1 month (t1), the diagnosis of PTSD at 3 (t2) and 6 (t3) months after transfer from the acute care ICU to the post-acute ICU...
July 5, 2017: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/28675115/nicotine-disrupts-safety-learning-by-enhancing-fear-associated-with-a-safety-cue-via-the-dorsal-hippocampus
#16
David A Connor, Munir G Kutlu, Thomas J Gould
Learned safety, a learning process in which a cue becomes associated with the absence of threat, is disrupted in individuals with post-traumatic stress disorder (PTSD). A bi-directional relationship exists between smoking and PTSD and one potential explanation is that nicotine-associated changes in cognition facilitate PTSD emotional dysregulation by disrupting safety associations. Therefore, we investigated whether nicotine would disrupt learned safety by enhancing fear associated with a safety cue. In the present study, C57BL/6 mice were administered acute or chronic nicotine and trained over three days in a differential backward trace conditioning paradigm consisting of five trials of a forward conditioned stimulus (CS)+ (Light) co-terminating with a footshock unconditioned stimulus followed by a backward CS- (Tone) presented 20 s after cessation of the unconditioned stimulus...
July 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28626847/injury-intense-dust-exposure-and-chronic-disease-among-survivors-of-the-world-trade-center-terrorist-attacks-of-september-11-2001
#17
Howard E Alper, Shengchao Yu, Steven D Stellman, Robert M Brackbill
BACKGROUND: The World Trade Center attack of September 11, 2001 in New York City (9/11) exposed thousands of people to intense concentrations of hazardous materials that have resulted in reports of increased levels of asthma, heart disease, diabetes, and other chronic diseases along with psychological illnesses such as post-traumatic stress disorder (PTSD). Few studies have discriminated between health consequences of immediate (short-term or acute) intense exposures versus chronic residential or workplace exposures...
December 2017: Injury Epidemiology
https://www.readbyqxmd.com/read/28604417/posttraumatic-stress-and-distress-tolerance-associations-with-suicidality-in-acute-care-psychiatric-inpatients
#18
Anka A Vujanovic, Jafar Bakhshaie, Colleen Martin, Madhavi K Reddy, Michael D Anestis
Trauma and posttraumatic stress disorder (PTSD) symptomatology have been associated with suicidality, including ideation and behavior. The current investigation evaluated, in acute-care psychiatric inpatients, the mediating role of perceived (self-reported) distress tolerance in the association between PTSD symptom severity and suicidality, defined as a) suicidal ideation, intent, or behavior leading to current psychiatric hospitalization; b) self-reported severity of suicidal desire; and c) percentage of days of suicidality during current hospitalization...
July 2017: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/28599071/predator-odor-evokes-sex-independent-stress-responses-in-male-and-female-wistar-rats-and-reduces-phosphorylation-of-cyclic-adenosine-monophosphate-response-element-binding-protein-in-the-male-but-not-the-female-hippocampus
#19
Damek Homiack, Emma O'Cinneide, Sema Hajmurad, Brett Barrileaux, Mary Stanley, Michael R Kreutz, Laura A Schrader
Post-traumatic stress disorder (PTSD) is characterized by memory disturbances following trauma. Acute predator threat has emerged as an ethological model of PTSD, yet the effects of predator odor on signaling cascades associated with long-term memory remain poorly understood. In this study, we exposed male and female Wistar rats to the synthetic predator odor 2,5-dihydro-2,4,5-trimethylthiazoline (TMT) to assess behavioral and physiological responses as well as rapid modulation of signal transduction cascades associated with learning and memory in the male and female hippocampus...
September 2017: Hippocampus
https://www.readbyqxmd.com/read/28577570/post-traumatic-stress-disorder-in-parturients-delivering-by-caesarean-section-and-the-implication-of-anaesthesia-a-prospective-cohort-study
#20
U Lopez, M Meyer, V Loures, I Iselin-Chaves, M Epiney, C Kern, G Haller
BACKGROUND: Post-traumatic stress disorder (PTSD) occurs in 1-7% of women following childbirth. While having a caesarean section (C-section) is known to be a significant risk factor for postpartum PTSD, it is currently unknown whether coexisting anaesthesia-related factors are also associated to the disorder. The aim of this study was to assess anaesthesia-linked factors in the development of acute postpartum PTSD. METHODS: We performed a prospective cohort study on women having a C-section in a tertiary hospital in Switzerland...
June 2, 2017: Health and Quality of Life Outcomes
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