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JOURNAL ARTICLE
K Silventoinen, A Jelenkovic, Y Yokoyama, R Sund, M Sugawara, M Tanaka, S Matsumoto, L H Bogl, D L Freitas, J A Maia, J V B Hjelmborg, S Aaltonen, M Piirtola, A Latvala, L Calais-Ferreira, V C Oliveira, P H Ferreira, F Ji, F Ning, Z Pang, J R Ordoñana, J F Sánchez-Romera, L Colodro-Conde, S A Burt, K L Klump, N G Martin, S E Medland, G W Montgomery, C Kandler, T A McAdams, T C Eley, A M Gregory, K J Saudino, L Dubois, M Boivin, M Brendgen, G Dionne, F Vitaro, A D Tarnoki, D L Tarnoki, C M A Haworth, R Plomin, S Y Öncel, F Aliev, E Medda, L Nisticò, V Toccaceli, J M Craig, R Saffery, S H Siribaddana, M Hotopf, A Sumathipala, F Rijsdijk, H-U Jeong, T Spector, M Mangino, G Lachance, M Gatz, D A Butler, W Gao, C Yu, L Li, G Bayasgalan, D Narandalai, K P Harden, E M Tucker-Drob, K Christensen, A Skytthe, K O Kyvik, C A Derom, R F Vlietinck, R J F Loos, W Cozen, A E Hwang, T M Mack, M He, X Ding, J L Silberg, H H Maes, T L Cutler, J L Hopper, P K E Magnusson, N L Pedersen, A K Dahl Aslan, L A Baker, C Tuvblad, M Bjerregaard-Andersen, H Beck-Nielsen, M Sodemann, V Ullemar, C Almqvist, Q Tan, D Zhang, G E Swan, R Krasnow, K L Jang, A Knafo-Noam, D Mankuta, L Abramson, P Lichtenstein, R F Krueger, M McGue, S Pahlen, P Tynelius, F Rasmussen, G E Duncan, D Buchwald, R P Corley, B M Huibregtse, T L Nelson, K E Whitfield, C E Franz, W S Kremen, M J Lyons, S Ooki, I Brandt, T S Nilsen, J R Harris, J Sung, H A Park, J Lee, S J Lee, G Willemsen, M Bartels, C E M van Beijsterveldt, C H Llewellyn, A Fisher, E Rebato, A Busjahn, R Tomizawa, F Inui, M Watanabe, C Honda, N Sakai, Y-M Hur, T I A Sørensen, D I Boomsma, J Kaprio
The COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) project is a large international collaborative effort to analyze individual-level phenotype data from twins in multiple cohorts from different environments. The main objective is to study factors that modify genetic and environmental variation of height, body mass index (BMI, kg/m2) and size at birth, and additionally to address other research questions such as long-term consequences of birth size. The project started in 2013 and is open to all twin projects in the world having height and weight measures on twins with information on zygosity...
July 31, 2019: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
#2
JOURNAL ARTICLE
Maarit Piirtola, Aline Jelenkovic, Antti Latvala, Reijo Sund, Chika Honda, Fujio Inui, Mikio Watanabe, Rie Tomizawa, Yoshinori Iwatani, Juan R Ordoñana, Juan F Sánchez-Romera, Lucia Colodro-Conde, Adam D Tarnoki, David L Tarnoki, Nicholas G Martin, Grant W Montgomery, Sarah E Medland, Finn Rasmussen, Per Tynelius, Qihua Tan, Dongfeng Zhang, Zengchang Pang, Esther Rebato, Maria A Stazi, Corrado Fagnani, Sonia Brescianini, Andreas Busjahn, Jennifer R Harris, Ingunn Brandt, Thomas Sevenius Nilsen, Tessa L Cutler, John L Hopper, Robin P Corley, Brooke M Huibregtse, Joohon Sung, Jina Kim, Jooyeon Lee, Sooji Lee, Margaret Gatz, David A Butler, Carol E Franz, William S Kremen, Michael J Lyons, Patrik K E Magnusson, Nancy L Pedersen, Anna K Dahl Aslan, Sevgi Y Öncel, Fazil Aliev, Catherine A Derom, Robert F Vlietinck, Ruth J F Loos, Judy L Silberg, Hermine H Maes, Dorret I Boomsma, Thorkild I A Sørensen, Tellervo Korhonen, Jaakko Kaprio, Karri Silventoinen
BACKGROUND: Smokers tend to weigh less than never smokers, while successful quitting leads to an increase in body weight. Because smokers and non-smokers may differ in genetic and environmental family background, we analysed data from twin pairs in which the co-twins differed by their smoking behaviour to evaluate if the association between smoking and body mass index (BMI) remains after controlling for family background. METHODS AND FINDINGS: The international CODATwins database includes information on smoking and BMI measured between 1960 and 2012 from 156,593 twin individuals 18-69 years of age...
2018: PloS One
#3
JOURNAL ARTICLE
Aline Jelenkovic, Reijo Sund, Yoshie Yokoyama, Yoon-Mi Hur, Vilhelmina Ullemar, Catarina Almqvist, Patrik Ke Magnusson, Gonneke Willemsen, Meike Bartels, Catharina Em van Beijsterveldt, Leonie H Bogl, Kirsi H Pietiläinen, Eero Vuoksimaa, Fuling Ji, Feng Ning, Zengchang Pang, Tracy L Nelson, Keith E Whitfield, Esther Rebato, Clare H Llewellyn, Abigail Fisher, Gombojav Bayasgalan, Danshiitsoodol Narandalai, Morten Bjerregaard-Andersen, Henning Beck-Nielsen, Morten Sodemann, Adam D Tarnoki, David L Tarnoki, Syuichi Ooki, Maria A Stazi, Corrado Fagnani, Sonia Brescianini, Lise Dubois, Michel Boivin, Mara Brendgen, Ginette Dionne, Frank Vitaro, Tessa L Cutler, John L Hopper, Robert F Krueger, Matt McGue, Shandell Pahlen, Jeffrey M Craig, Richard Saffery, Claire Ma Haworth, Robert Plomin, Ariel Knafo-Noam, David Mankuta, Lior Abramson, S Alexandra Burt, Kelly L Klump, Robert F Vlietinck, Catherine A Derom, Ruth Jf Loos, Dorret I Boomsma, Thorkild I A Sørensen, Jaakko Kaprio, Karri Silventoinen
It is well established that boys are born heavier and longer than girls, but it remains unclear whether birth size in twins is affected by the sex of their co-twin. We conducted an individual-based pooled analysis of 21 twin cohorts in 15 countries derived from the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins), including 67,850 dizygotic twin individuals. Linear regression analyses showed that boys having a co-twin sister were, on average, 31 g (95% CI 18 to 45) heavier and 0...
April 19, 2018: Scientific Reports
#4
JOURNAL ARTICLE
Aline Jelenkovic, Yoshie Yokoyama, Reijo Sund, Yoon-Mi Hur, Jennifer R Harris, Ingunn Brandt, Thomas Sevenius Nilsen, Syuichi Ooki, Vilhelmina Ullemar, Catarina Almqvist, Patrik K E Magnusson, Kimberly J Saudino, Maria A Stazi, Corrado Fagnani, Sonia Brescianini, Tracy L Nelson, Keith E Whitfield, Ariel Knafo-Noam, David Mankuta, Lior Abramson, Tessa L Cutler, John L Hopper, Clare H Llewellyn, Abigail Fisher, Robin P Corley, Brooke M Huibregtse, Catherine A Derom, Robert F Vlietinck, Morten Bjerregaard-Andersen, Henning Beck-Nielsen, Morten Sodemann, Robert F Krueger, Matt McGue, Shandell Pahlen, S Alexandra Burt, Kelly L Klump, Lise Dubois, Michel Boivin, Mara Brendgen, Ginette Dionne, Frank Vitaro, Gonneke Willemsen, Meike Bartels, Catharina E M van Beijsterveld, Jeffrey M Craig, Richard Saffery, Finn Rasmussen, Per Tynelius, Kauko Heikkilä, Kirsi H Pietiläinen, Gombojav Bayasgalan, Danshiitsoodol Narandalai, Claire M A Haworth, Robert Plomin, Fuling Ji, Feng Ning, Zengchang Pang, Esther Rebato, Adam D Tarnoki, David L Tarnoki, Jina Kim, Jooyeon Lee, Sooji Lee, Joohon Sung, Ruth J F Loos, Dorret I Boomsma, Thorkild I A Sørensen, Jaakko Kaprio, Karri Silventoinen
BACKGROUND: There is evidence that birth size is positively associated with height in later life, but it remains unclear whether this is explained by genetic factors or the intrauterine environment. AIM: To analyze the associations of birth weight, length and ponderal index with height from infancy through adulthood within mono- and dizygotic twin pairs, which provides insights into the role of genetic and environmental individual-specific factors. METHODS: This study is based on the data from 28 twin cohorts in 17 countries...
May 2018: Early Human Development
#5
JOURNAL ARTICLE
Leonie H Bogl, Aline Jelenkovic, Eero Vuoksimaa, Linda Ahrenfeldt, Kirsi H Pietiläinen, Maria A Stazi, Corrado Fagnani, Cristina D'Ippolito, Yoon-Mi Hur, Hoe-Uk Jeong, Judy L Silberg, Lindon J Eaves, Hermine H Maes, Gombojav Bayasgalan, Danshiitsoodol Narandalai, Tessa L Cutler, Christian Kandler, Kerry L Jang, Kaare Christensen, Axel Skytthe, Kirsten O Kyvik, Wendy Cozen, Amie E Hwang, Thomas M Mack, Catherine A Derom, Robert F Vlietinck, Tracy L Nelson, Keith E Whitfield, Robin P Corley, Brooke M Huibregtse, Tom A McAdams, Thalia C Eley, Alice M Gregory, Robert F Krueger, Matt McGue, Shandell Pahlen, Gonneke Willemsen, Meike Bartels, Toos C E M van Beijsterveldt, Zengchang Pang, Qihua Tan, Dongfeng Zhang, Nicholas G Martin, Sarah E Medland, Grant W Montgomery, Jacob V B Hjelmborg, Esther Rebato, Gary E Swan, Ruth Krasnow, Andreas Busjahn, Paul Lichtenstein, Sevgi Y Öncel, Fazil Aliev, Laura A Baker, Catherine Tuvblad, Sisira H Siribaddana, Matthew Hotopf, Athula Sumathipala, Fruhling Rijsdijk, Patrik K E Magnusson, Nancy L Pedersen, Anna K Dahl Aslan, Juan R Ordoñana, Juan F Sánchez-Romera, Lucia Colodro-Conde, Glen E Duncan, Dedra Buchwald, Adam D Tarnoki, David L Tarnoki, Yoshie Yokoyama, John L Hopper, Ruth J F Loos, Dorret I Boomsma, Thorkild I A Sørensen, Karri Silventoinen, Jaakko Kaprio
BACKGROUND: The comparison of traits in twins from opposite-sex (OS) and same-sex (SS) dizygotic twin pairs is considered a proxy measure of prenatal hormone exposure. To examine possible prenatal hormonal influences on anthropometric traits, we compared mean height, body mass index (BMI), and the prevalence of being overweight or obese between men and women from OS and SS dizygotic twin pairs. METHODS: The data were derived from the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) database, and included 68,494 SS and 53,808 OS dizygotic twin individuals above the age of 20 years from 31 twin cohorts representing 19 countries...
2017: Biology of Sex Differences
#6
JOURNAL ARTICLE
Aline Jelenkovic, Yoshie Yokoyama, Reijo Sund, Kirsi H Pietiläinen, Yoon-Mi Hur, Gonneke Willemsen, Meike Bartels, Toos C E M van Beijsterveldt, Syuichi Ooki, Kimberly J Saudino, Maria A Stazi, Corrado Fagnani, Cristina D'Ippolito, Tracy L Nelson, Keith E Whitfield, Ariel Knafo-Noam, David Mankuta, Lior Abramson, Kauko Heikkilä, Tessa L Cutler, John L Hopper, Jane Wardle, Clare H Llewellyn, Abigail Fisher, Robin P Corley, Brooke M Huibregtse, Catherine A Derom, Robert F Vlietinck, Ruth J F Loos, Morten Bjerregaard-Andersen, Henning Beck-Nielsen, Morten Sodemann, Adam D Tarnoki, David L Tarnoki, S Alexandra Burt, Kelly L Klump, Juan R Ordoñana, Juan F Sánchez-Romera, Lucia Colodro-Conde, Lise Dubois, Michel Boivin, Mara Brendgen, Ginette Dionne, Frank Vitaro, Jennifer R Harris, Ingunn Brandt, Thomas Sevenius Nilsen, Jeffrey M Craig, Richard Saffery, Finn Rasmussen, Per Tynelius, Gombojav Bayasgalan, Danshiitsoodol Narandalai, Claire M A Haworth, Robert Plomin, Fuling Ji, Feng Ning, Zengchang Pang, Esther Rebato, Robert F Krueger, Matt McGue, Shandell Pahlen, Dorret I Boomsma, Thorkild I A Sørensen, Jaakko Kaprio, Karri Silventoinen
Background: There is evidence that birthweight is positively associated with body mass index (BMI) in later life, but it remains unclear whether this is explained by genetic factors or the intrauterine environment. We analysed the association between birthweight and BMI from infancy to adulthood within twin pairs, which provides insights into the role of genetic and environmental individual-specific factors. Methods: This study is based on the data from 27 twin cohorts in 17 countries...
October 1, 2017: International Journal of Epidemiology
#7
JOURNAL ARTICLE
Karri Silventoinen, Aline Jelenkovic, Reijo Sund, Yoon-Mi Hur, Yoshie Yokoyama, Chika Honda, Jacob vB Hjelmborg, Sören Möller, Syuichi Ooki, Sari Aaltonen, Fuling Ji, Feng Ning, Zengchang Pang, Esther Rebato, Andreas Busjahn, Christian Kandler, Kimberly J Saudino, Kerry L Jang, Wendy Cozen, Amie E Hwang, Thomas M Mack, Wenjing Gao, Canqing Yu, Liming Li, Robin P Corley, Brooke M Huibregtse, Kaare Christensen, Axel Skytthe, Kirsten O Kyvik, Catherine A Derom, Robert F Vlietinck, Ruth Jf Loos, Kauko Heikkilä, Jane Wardle, Clare H Llewellyn, Abigail Fisher, Tom A McAdams, Thalia C Eley, Alice M Gregory, Mingguang He, Xiaohu Ding, Morten Bjerregaard-Andersen, Henning Beck-Nielsen, Morten Sodemann, Adam D Tarnoki, David L Tarnoki, Maria A Stazi, Corrado Fagnani, Cristina D'Ippolito, Ariel Knafo-Noam, David Mankuta, Lior Abramson, S Alexandra Burt, Kelly L Klump, Judy L Silberg, Lindon J Eaves, Hermine H Maes, Robert F Krueger, Matt McGue, Shandell Pahlen, Margaret Gatz, David A Butler, Meike Bartels, Toos Cem van Beijsterveldt, Jeffrey M Craig, Richard Saffery, Duarte L Freitas, José Antonio Maia, Lise Dubois, Michel Boivin, Mara Brendgen, Ginette Dionne, Frank Vitaro, Nicholas G Martin, Sarah E Medland, Grant W Montgomery, Youngsook Chong, Gary E Swan, Ruth Krasnow, Patrik Ke Magnusson, Nancy L Pedersen, Per Tynelius, Paul Lichtenstein, Claire Ma Haworth, Robert Plomin, Gombojav Bayasgalan, Danshiitsoodol Narandalai, K Paige Harden, Elliot M Tucker-Drob, Sevgi Y Öncel, Fazil Aliev, Timothy Spector, Massimo Mangino, Genevieve Lachance, Laura A Baker, Catherine Tuvblad, Glen E Duncan, Dedra Buchwald, Gonneke Willemsen, Finn Rasmussen, Jack H Goldberg, Thorkild Ia Sørensen, Dorret I Boomsma, Jaakko Kaprio
BACKGROUND: Both genetic and environmental factors are known to affect body mass index (BMI), but detailed understanding of how their effects differ during childhood and adolescence is lacking. OBJECTIVES: We analyzed the genetic and environmental contributions to BMI variation from infancy to early adulthood and the ways they differ by sex and geographic regions representing high (North America and Australia), moderate (Europe), and low levels (East Asia) of obesogenic environments...
August 2016: American Journal of Clinical Nutrition
#8
JOURNAL ARTICLE
Yoshie Yokoyama, Aline Jelenkovic, Reijo Sund, Joohon Sung, John L Hopper, Syuichi Ooki, Kauko Heikkilä, Sari Aaltonen, Adam D Tarnoki, David L Tarnoki, Gonneke Willemsen, Meike Bartels, Toos C E M van Beijsterveldt, Kimberly J Saudino, Tessa L Cutler, Tracy L Nelson, Keith E Whitfield, Jane Wardle, Clare H Llewellyn, Abigail Fisher, Mingguang He, Xiaohu Ding, Morten Bjerregaard-Andersen, Henning Beck-Nielsen, Morten Sodemann, Yun-Mi Song, Sarah Yang, Kayoung Lee, Hoe-Uk Jeong, Ariel Knafo-Noam, David Mankuta, Lior Abramson, S Alexandra Burt, Kelly L Klump, Juan R Ordoñana, Juan F Sánchez-Romera, Lucia Colodro-Conde, Jennifer R Harris, Ingunn Brandt, Thomas Sevenius Nilsen, Jeffrey M Craig, Richard Saffery, Fuling Ji, Feng Ning, Zengchang Pang, Lise Dubois, Michel Boivin, Mara Brendgen, Ginette Dionne, Frank Vitaro, Nicholas G Martin, Sarah E Medland, Grant W Montgomery, Patrik K E Magnusson, Nancy L Pedersen, Anna K Dahl Aslan, Per Tynelius, Claire M A Haworth, Robert Plomin, Esther Rebato, Richard J Rose, Jack H Goldberg, Finn Rasmussen, Yoon-Mi Hur, Thorkild I A Sørensen, Dorret I Boomsma, Jaakko Kaprio, Karri Silventoinen
We analyzed birth order differences in means and variances of height and body mass index (BMI) in monozygotic (MZ) and dizygotic (DZ) twins from infancy to old age. The data were derived from the international CODATwins database. The total number of height and BMI measures from 0.5 to 79.5 years of age was 397,466. As expected, first-born twins had greater birth weight than second-born twins. With respect to height, first-born twins were slightly taller than second-born twins in childhood. After adjusting the results for birth weight, the birth order differences decreased and were no longer statistically significant...
April 2016: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
#9
JOURNAL ARTICLE
Aline Jelenkovic, Yoshie Yokoyama, Reijo Sund, Chika Honda, Leonie H Bogl, Sari Aaltonen, Fuling Ji, Feng Ning, Zengchang Pang, Juan R Ordoñana, Juan F Sánchez-Romera, Lucia Colodro-Conde, S Alexandra Burt, Kelly L Klump, Sarah E Medland, Grant W Montgomery, Christian Kandler, Tom A McAdams, Thalia C Eley, Alice M Gregory, Kimberly J Saudino, Lise Dubois, Michel Boivin, Adam D Tarnoki, David L Tarnoki, Claire M A Haworth, Robert Plomin, Sevgi Y Öncel, Fazil Aliev, Maria A Stazi, Corrado Fagnani, Cristina D'Ippolito, Jeffrey M Craig, Richard Saffery, Sisira H Siribaddana, Matthew Hotopf, Athula Sumathipala, Fruhling Rijsdijk, Timothy Spector, Massimo Mangino, Genevieve Lachance, Margaret Gatz, David A Butler, Gombojav Bayasgalan, Danshiitsoodol Narandalai, Duarte L Freitas, José Antonio Maia, K Paige Harden, Elliot M Tucker-Drob, Bia Kim, Youngsook Chong, Changhee Hong, Hyun Jung Shin, Kaare Christensen, Axel Skytthe, Kirsten O Kyvik, Catherine A Derom, Robert F Vlietinck, Ruth J F Loos, Wendy Cozen, Amie E Hwang, Thomas M Mack, Mingguang He, Xiaohu Ding, Billy Chang, Judy L Silberg, Lindon J Eaves, Hermine H Maes, Tessa L Cutler, John L Hopper, Kelly Aujard, Patrik K E Magnusson, Nancy L Pedersen, Anna K Dahl Aslan, Yun-Mi Song, Sarah Yang, Kayoung Lee, Laura A Baker, Catherine Tuvblad, Morten Bjerregaard-Andersen, Henning Beck-Nielsen, Morten Sodemann, Kauko Heikkilä, Qihua Tan, Dongfeng Zhang, Gary E Swan, Ruth Krasnow, Kerry L Jang, Ariel Knafo-Noam, David Mankuta, Lior Abramson, Paul Lichtenstein, Robert F Krueger, Matt McGue, Shandell Pahlen, Per Tynelius, Glen E Duncan, Dedra Buchwald, Robin P Corley, Brooke M Huibregtse, Tracy L Nelson, Keith E Whitfield, Carol E Franz, William S Kremen, Michael J Lyons, Syuichi Ooki, Ingunn Brandt, Thomas Sevenius Nilsen, Fujio Inui, Mikio Watanabe, Meike Bartels, Toos C E M van Beijsterveldt, Jane Wardle, Clare H Llewellyn, Abigail Fisher, Esther Rebato, Nicholas G Martin, Yoshinori Iwatani, Kazuo Hayakawa, Joohon Sung, Jennifer R Harris, Gonneke Willemsen, Andreas Busjahn, Jack H Goldberg, Finn Rasmussen, Yoon-Mi Hur, Dorret I Boomsma, Thorkild I A Sørensen, Jaakko Kaprio, Karri Silventoinen
A trend toward greater body size in dizygotic (DZ) than in monozygotic (MZ) twins has been suggested by some but not all studies, and this difference may also vary by age. We analyzed zygosity differences in mean values and variances of height and body mass index (BMI) among male and female twins from infancy to old age. Data were derived from an international database of 54 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins), and included 842,951 height and BMI measurements from twins aged 1 to 102 years...
October 2015: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
#10
JOURNAL ARTICLE
Karri Silventoinen, Aline Jelenkovic, Reijo Sund, Chika Honda, Sari Aaltonen, Yoshie Yokoyama, Adam D Tarnoki, David L Tarnoki, Feng Ning, Fuling Ji, Zengchang Pang, Juan R Ordoñana, Juan F Sánchez-Romera, Lucia Colodro-Conde, S Alexandra Burt, Kelly L Klump, Sarah E Medland, Grant W Montgomery, Christian Kandler, Tom A McAdams, Thalia C Eley, Alice M Gregory, Kimberly J Saudino, Lise Dubois, Michel Boivin, Claire M A Haworth, Robert Plomin, Sevgi Y Öncel, Fazil Aliev, Maria A Stazi, Corrado Fagnani, Cristina D'Ippolito, Jeffrey M Craig, Richard Saffery, Sisira H Siribaddana, Matthew Hotopf, Athula Sumathipala, Timothy Spector, Massimo Mangino, Genevieve Lachance, Margaret Gatz, David A Butler, Gombojav Bayasgalan, Danshiitsoodol Narandalai, Duarte L Freitas, José Antonio Maia, K Paige Harden, Elliot M Tucker-Drob, Kaare Christensen, Axel Skytthe, Kirsten O Kyvik, Changhee Hong, Youngsook Chong, Catherine A Derom, Robert F Vlietinck, Ruth J F Loos, Wendy Cozen, Amie E Hwang, Thomas M Mack, Mingguang He, Xiaohu Ding, Billy Chang, Judy L Silberg, Lindon J Eaves, Hermine H Maes, Tessa L Cutler, John L Hopper, Kelly Aujard, Patrik K E Magnusson, Nancy L Pedersen, Anna K Dahl Aslan, Yun-Mi Song, Sarah Yang, Kayoung Lee, Laura A Baker, Catherine Tuvblad, Morten Bjerregaard-Andersen, Henning Beck-Nielsen, Morten Sodemann, Kauko Heikkilä, Qihua Tan, Dongfeng Zhang, Gary E Swan, Ruth Krasnow, Kerry L Jang, Ariel Knafo-Noam, David Mankuta, Lior Abramson, Paul Lichtenstein, Robert F Krueger, Matt McGue, Shandell Pahlen, Per Tynelius, Glen E Duncan, Dedra Buchwald, Robin P Corley, Brooke M Huibregtse, Tracy L Nelson, Keith E Whitfield, Carol E Franz, William S Kremen, Michael J Lyons, Syuichi Ooki, Ingunn Brandt, Thomas Sevenius Nilsen, Fujio Inui, Mikio Watanabe, Meike Bartels, Toos C E M van Beijsterveldt, Jane Wardle, Clare H Llewellyn, Abigail Fisher, Esther Rebato, Nicholas G Martin, Yoshinori Iwatani, Kazuo Hayakawa, Finn Rasmussen, Joohon Sung, Jennifer R Harris, Gonneke Willemsen, Andreas Busjahn, Jack H Goldberg, Dorret I Boomsma, Yoon-Mi Hur, Thorkild I A Sørensen, Jaakko Kaprio
For over 100 years, the genetics of human anthropometric traits has attracted scientific interest. In particular, height and body mass index (BMI, calculated as kg/m2) have been under intensive genetic research. However, it is still largely unknown whether and how heritability estimates vary between human populations. Opportunities to address this question have increased recently because of the establishment of many new twin cohorts and the increasing accumulation of data in established twin cohorts. We started a new research project to analyze systematically (1) the variation of heritability estimates of height, BMI and their trajectories over the life course between birth cohorts, ethnicities and countries, and (2) to study the effects of birth-related factors, education and smoking on these anthropometric traits and whether these effects vary between twin cohorts...
August 2015: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
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