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Substance-Related Disorders

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https://www.readbyqxmd.com/read/28531824/is-subclinical-gambling-really-subclinical
#1
Jeremiah Weinstock, Laura M April, Selmi Kallmi
Gambling disorder and substance use disorders (SUD) overlap in terms of etiology and diagnostic constructs (e.g., preoccupation, loss of control), yet diagnostic thresholds for the disorders are different. Currently, endorsing 2-3 gambling disorder criteria does not warrant a diagnosis while endorsing 2-3 SUD criteria does. The aim of this study was to examine whether subclinical gamblers (i.e., endorsing 2-3 gambling disorder criteria) experience psychosocial dysfunction equivalent to individuals who are diagnosed with mild severity SUD (i...
May 15, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28531653/characteristics-needs-and-experiences-of-u-s-veterans-on-a-specialized-prison-unit
#2
Jack Tsai, Elizabeth Goggin
The Veterans Service Unit (VSU) in Connecticut is one of several all-veterans prison units that are being created throughout the United States. This study examined the characteristics, needs, and experiences of veterans on the Connecticut VSU. This study utilized data from a quality improvement survey that was completed by 87 of the 110 veterans on the Connecticut VSU (79% response rate). The majority of veterans on the VSU were white, aged 41-56, never married, and had an honorable or general military discharge making them potentially eligible for Veterans Affairs (VA) healthcare upon release...
May 17, 2017: Evaluation and Program Planning
https://www.readbyqxmd.com/read/28531646/lifetime-presence-of-psychotic-symptoms-in-bipolar-disorder-is-associated-with-less-favorable-socio-demographic-and-certain-clinical-features
#3
Bernardo Dell'Osso, Giulia Camuri, Laura Cremaschi, Cristina Dobrea, Massimiliano Buoli, Terence A Ketter, A Carlo Altamura
BACKGROUND: The presence of psychotic symptoms in bipolar disorder (BD) is considered a feature of higher severity of illness and, in particular, of manic episodes in bipolar I disorder (BD I). However, the possibility to apply the "with psychotic features" specifier to major depressive episodes in either bipolar II disorder (BD II) or BD I highlights the need for additional research in this area. METHODS: The present study assessed the lifetime presence of psychotic symptoms and related socio-demographic and clinical features in a large sample of BD patients (N=360), with (BDPs, N=207) and without a lifetime history of psychosis (BDNPs, N=153)...
April 21, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28531265/utility-of-nonhuman-primates-in-substance-use-disorders-research
#4
Matthew L Banks, Paul W Czoty, Sidney S Negus
Substance use disorders (i.e., drug addiction) constitute a global and insidious public health issue. Preclinical biomedical research has been invaluable in elucidating the environmental, biological, and pharmacological determinants of drug abuse and in the process of developing innovative pharmacological and behavioral treatment strategies. For more than 70 years, nonhuman primates have been utilized as research subjects in biomedical research related to drug addiction. There are already several excellent published reviews highlighting species differences in both pharmacodynamics and pharmacokinetics between rodents and nonhuman primates in preclinical substance abuse research...
May 20, 2017: ILAR Journal
https://www.readbyqxmd.com/read/28530317/-long-term-survival-of-dual-disorders-patients-after-mixed-care-in-dual-disorders-and-standard-wards-versus-care-only-in-dual-disorders-ward
#5
Yuri Gimelfarb, Aviva Wolf, Mashit Ben-Tzarfati
BACKGROUND: Dual disorders (co-occurring mental illness and substance abuse disorders in the same person) are extremely common among patients receiving mental health services. Integrated treatment has been proposed as the standard of care and it describes a flexible combination of treatments from the mental health and addiction fields that are blended together in the therapy. Scientific evidence for survival of dual disorders patients (DDPs), who had integrated dual disorders inpatient care, is lacking...
January 2017: Harefuah
https://www.readbyqxmd.com/read/28529363/treatment-compliance-and-noncompliance-in-psychoses
#6
K Nagaraja Rao, Jitty George, C Y Sudarshan, Shamshad Begum
BACKGROUND: Compliance or noncompliance with treatment significantly influences course and outcome of psychiatric disorders. While noncompliance has been extensively researched, compliance has received less attention. The current study was conducted to elicit reasons for compliance and noncompliance in patients having psychoses attending psychiatric clinics. MATERIALS AND METHODS: A total of 196 compliant and 150 noncompliant patients were interviewed using self-designed tools to elicit sociodemographic data, details of illness, and treatment...
January 2017: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28529360/twelve-month-prevalence-and-treatment-gap-for-common-mental-disorders-findings-from-a-large-scale-epidemiological-survey-in-india
#7
Rajesh Sagar, Raman Deep Pattanayak, R Chandrasekaran, Pranit K Chaudhury, Balbir S Deswal, R K Lenin Singh, Savita Malhotra, S Haque Nizamie, Bharat N Panchal, T P Sudhakar, J K Trivedi, Mathew Varghese, Jagdish Prasad, Somnath Chatterji
BACKGROUND: Common mental disorders, such as mood, anxiety, and substance use disorders, are significant contributors to disability globally, including India. Available research is, however, limited by methodological issues and heterogeneities. AIM: The present paper focuses on the 12-month prevalence and 12-month treatment for anxiety, mood, and substance use disorders in India. MATERIALS AND METHODS: As part of the World Health Organization World Mental Health (WMH) Survey Initiative, in India, the study was conducted at eleven sites...
January 2017: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28528115/alcohol-and-other-substance-use-after-bariatric-surgery-prospective-evidence-from-a-u-s-multicenter-cohort-study
#8
Wendy C King, Jia-Yuh Chen, Anita P Courcoulas, Gregory F Dakin, Scott G Engel, David R Flum, Marcelo W Hinojosa, Melissa A Kalarchian, Samer G Mattar, James E Mitchell, Alfons Pomp, Walter J Pories, Kristine J Steffen, Gretchen E White, Bruce M Wolfe, Susan Z Yanovski
BACKGROUND: Empirical evidence suggests Roux-en-Y gastric bypass (RYGB) increases risk of developing alcohol use disorder (AUD). However, prospective assessment of substance use disorders (SUD) after bariatric surgery is limited. OBJECTIVE: To report SUD-related outcomes after RYGB and laparoscopic adjustable gastric banding (LAGB). To identify factors associated with incident SUD-related outcomes. SETTING: 10 U.S. hospitals METHODS: The Longitudinal Assessment of Bariatric Surgery-2 is a prospective cohort study...
March 31, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28523674/massachusetts-health-reform-s-effect-on-hospitalizations-with-substance-use-disorder-related-diagnoses
#9
Karen E Lasser, Amresh D Hanchate, Danny McCormick, Alexander Y Walley, Richard Saitz, Meng-Yun Lin, Nancy R Kressin
OBJECTIVE: To examine whether Massachusetts (MA) health reform affected substance (alcohol or drug) use disorder (SUD)-related hospitalizations in acute care hospitals. DATA/STUDY SETTING: 2004-2010 MA inpatient discharge data. DESIGN: Difference-in-differences analysis to identify pre- to postreform changes in age- and sex-standardized population-based rates of SUD-related medical and surgical hospitalizations, adjusting for secular trends...
May 19, 2017: Health Services Research
https://www.readbyqxmd.com/read/28523545/anxiety-and-epigenetics
#10
Andrew A Bartlett, Rumani Singh, Richard G Hunter
Anxiety disorders are highly prevalent psychiatric disorders often comorbid with depression and substance abuse. Twin studies have shown that anxiety disorders are moderately heritable. Yet, genome-wide association studies (GWASs) have failed to identify gene(s) significantly associated with diagnosis suggesting a strong role for environmental factors and the epigenome. A number of anxiety disorder subtypes are considered "stress related." A large focus of research has been on the epigenetic and anxiety-like behavioral consequences of stress...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28521814/access-to-healthcare-insurance-and-healthcare-services-among-syringe-exchange-program-clients-in-massachusetts-qualitative-findings-from-health-navigators-with-the-idu-i-do-care-collaborative
#11
Thomas J Stopka, Marguerite Hutcheson, Ashley Donahue
BACKGROUND: Little is known about access to health insurance among people who inject drugs (PWID) who attend syringe exchange programs (SEPs). The goal of the current study was to assess perceptions of SEP staff, including health navigators and program managers, on access to health insurance and healthcare access among SEP clients following implementation of state and federal policies to enhance universal healthcare access in Massachusetts. METHODS: Between December 2014 and January 2015, we conducted in-depth interviews (n = 14) with SEP staff, including both program managers and health navigators, to assess knowledge, attitudes, and beliefs related to health insurance enrollment and access to enhanced referrals among SEP clients...
May 18, 2017: Harm Reduction Journal
https://www.readbyqxmd.com/read/28521670/intranasal-drug-delivery-a-non-invasive-approach-for-the-better-delivery-of-neurotherapeutics
#12
Umesh Gupta, Hitesh Kumar, Gaurav Mishra, Ashok Kumar Sharma, Avinash Gothwal, Prashant Kesharwani
BACKGROUND: The convoluted pathophysiology of brain disorders along with penetration issue of drugs to brain represents major hurdle that requires some novel therapies. The blood-brain barrier (BBB) denotes a rigid barrier for delivery of therapeutics in vivo, to overcome this barrier intranasal delivery is an excellent strategy to deliver the drug directly to brain via olfactory and trigeminal nerve pathways that originate as olfactory neuro-epithelium in the nasal cavity and terminate in brain...
May 14, 2017: Pharmaceutical Nanotechnology
https://www.readbyqxmd.com/read/28517032/novel-psychoactive-substance-consumption-is-more-represented-in-bipolar-disorder-than-in-psychotic-disorders-a-multicenter-observational-study
#13
Tiziano Acciavatti, Matteo Lupi, Rita Santacroce, Andrea Aguglia, Luigi Attademo, Laura Bandini, Paola Ciambrone, Giulia Lisi, Giovanni Migliarese, Federica Pinna, Diego Quattrone, Michele Ribolsi, Maria Salvina Signorelli, Salvatore Calò, Fabrizio Schifano, Massimo di Giannantonio, Giovanni Martinotti
OBJECTIVE: Comorbidities between psychiatric diseases and use of traditional substances of abuse are common. Nevertheless, there are few data regarding the use of novel psychoactive substances (NPS) among psychiatric patients. Aim of this multicentre survey is to investigate the consumption of a number of psychoactive substances in a young psychiatric sample. METHODS: Between December 2013 and September 2015, a questionnaire was administered in 10 Italian psychiatric care facilities to a sample of 671 patients, aged 18-26 (mean age 22...
May 18, 2017: Human Psychopharmacology
https://www.readbyqxmd.com/read/28513339/juggling-thoughts-and-feelings-how-do-female-patients-with-borderline-symptomology-and-substance-use-disorder-experience-change-in-mentalization-based-treatment
#14
Katharina T E Morken, Per Einar Binder, Nina Arefjord, Sigmund Karterud
OBJECTIVE: The aim of this study was to explore the experience of central psychological change processes for female patients with borderline symptomology and substance use disorder in mentalization-based treatment. METHOD: Semi-structured qualitative interviews on experiences from mentalization-based treatment with 13 participants were conducted. The interview material was analysed within a hermeneutical-phenomenological epistemology, with emphasis on researcher reflexivity...
May 17, 2017: Psychotherapy Research: Journal of the Society for Psychotherapy Research
https://www.readbyqxmd.com/read/28511824/psychiatric-disorders-and-pruritus
#15
Helen Gin Lee, Carolyn Stull, Gil Yosipovitch
The skin and psyche are intimately related with various skin diseases caused by or resulting in psychiatric disturbances. Pruritus is a commonly reported symptom in psychiatric patients, and likewise psychiatric co-morbidities, including anxiety and depression, are frequently seen in chronic pruritus patients. Primary psychodermatologic conditions, such as somatic symptom disorder, dermatitis artefacta, obsessive-compulsive and related disorders (excoriation disorder and prurigo nodularis), delusional infestation, and substance use disorder, can all induce significant pruritus in patients, severely affecting their quality of life...
May 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/28511259/impulse-control-disorders-and-related-complications-of-parkinson-s-disease-therapy
#16
Alexander M Lopez, Daniel Weintraub, Daniel O Claassen
Impulsive and compulsive behaviors in Parkinson's disease (PD) patients are most often attributed to dopamine agonist therapy; dysregulation of the mesocorticolimbic system accounts for this behavioral phenotype. The clinical presentation is commonly termed impulse control disorder (ICD): Behaviors include hypersexuality, compulsive eating, shopping, pathological gambling, and compulsive hobby participation. However, not all PD individuals taking dopamine agonists develop these behavioral changes. In this review, the authors focus on the similarities between the phenotypic presentation of ICDs with that of other reward-based behavioral disorders, including binge eating disorder, pathological gambling, and substance use disorders...
April 2017: Seminars in Neurology
https://www.readbyqxmd.com/read/28511033/comparing-adult-cannabis-treatment-seekers-enrolled-in-a-clinical-trial-with-national-samples-of-cannabis-users-in-the-united-states
#17
Erin A McClure, Jacqueline S King, Aimee Wahle, Abigail G Matthews, Susan C Sonne, Michelle R Lofwall, Aimee L McRae-Clark, Udi E Ghitza, Melissa Martinez, Kasie Cloud, Harvir S Virk, Kevin M Gray
BACKGROUND: Cannabis use rates are increasing among adults in the United States (US) while the perception of harm is declining. This may result in an increased prevalence of cannabis use disorder and the need for more clinical trials to evaluate efficacious treatment strategies. Clinical trials are the gold standard for evaluating treatment, yet study samples are rarely representative of the target population. This finding has not yet been established for cannabis treatment trials. This study compared demographic and cannabis use characteristics of a cannabis cessation clinical trial sample (run through National Drug Abuse Treatment Clinical Trials Network) with three nationally representative datasets from the US; 1) National Survey on Drug Use and Health, 2) National Epidemiologic Survey on Alcohol and Related Conditions-III, and 3) Treatment: Episodes Data Set - Admissions...
May 10, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28504027/epidemiology-and-comorbidity-of-obsessive-compulsive-disorder-in-late-adolescence-a-cross-sectional-study-in-senior-high-schools-in-greece
#18
Spyridon Politis, Konstantina Magklara, Petros Petrikis, Grigorios Michalis, Gregoris Simos, Petros Skapinakis
OBJECTIVE: The aim of this study was to examine the epidemiology, comorbidity and use of health services of obsessive-compulsive disorder (OCD) and subclinical obsessive-compulsive symptoms in late adolescence. METHODS: A total of 2427 adolescents attending senior high schools in Greece were selected for a detailed psychiatric interview using the revised clinical interview schedule (CIS-R). Use of alcohol, nicotine and cannabis, and several socio-demographic and socio-economic variables were also assessed...
May 15, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/28501291/use-and-dependence-on-opioid-drugs-in-the-spanish-population-with-chronic-pain-prevalence-and-differences-according-to-sex
#19
A Coloma-Carmona, J L Carballo, J Rodríguez-Marín, A Pérez-Carbonell
OBJECTIVES: To analyse the prevalence in the use and dependence on opioid drugs in the Spanish population with chronic pain and evaluate the differences according to sex. PATIENTS AND METHODS: The demographic variables, opioid treatment characteristics and use of other substances were assessed in 229 users of opioid drugs. A descriptive bivariate analysis of the data was performed. RESULTS: Forty-six percent of the patients met the criteria of dependence on opioid drugs (Diagnostic and Statistical Manual of Mental Disorders, 4th Edition [DSM-IV-TR])...
May 10, 2017: Revista Clínica Española
https://www.readbyqxmd.com/read/28500922/adverse-childhood-experiences-and-suicide-attempts-among-those-with-mental-and-substance-use-disorders
#20
Namkee G Choi, Diana M DiNitto, C Nathan Marti, Steven P Segal
Using the 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions data, we examined the associations of ten types of adverse childhood experiences (ACEs) with (1) lifetime suicide attempts and (2) number and age of attempts among U.S. adults aged 18+. In a case-control design, suicide attempters (5.14% of the full sample) were matched with never attempters (matched sample N=3912) on nine mental and substance use disorders. ACE rates were higher among attempters (3.30 [SE=0.07]) than their matched controls (2...
May 10, 2017: Child Abuse & Neglect
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