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Substance-Related Disorders

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https://www.readbyqxmd.com/read/29792052/randomized-clinical-trial-of-computerized-and-clinician-delivered-cbt-in-comparison-with-standard-outpatient-treatment-for-substance-use-disorders-primary-within-treatment-and-follow-up-outcomes
#1
Brian D Kiluk, Charla Nich, Matthew B Buck, Kathleen A Devore, Tami L Frankforter, Donna M LaPaglia, Srinivas B Muvvala, Kathleen M Carroll
OBJECTIVE: Previous trials have demonstrated the efficacy and durability of computer-based cognitive-behavioral therapy (CBT4CBT) as an add-on to standard outpatient care in a range of treatment-seeking populations. In this study, the authors evaluated the efficacy and safety of CBT4CBT as a virtual stand-alone treatment, delivered with minimal clinical monitoring, and clinician-delivered cognitive-behavioral therapy (CBT) compared with treatment as usual in a heterogeneous sample of treatment-seeking outpatients with substance use disorders...
May 24, 2018: American Journal of Psychiatry
https://www.readbyqxmd.com/read/29787925/the-association-between-perceived-distress-tolerance-and-cannabis-use-problems-cannabis-withdrawal-symptoms-and-self-efficacy-for-quitting-cannabis-the-explanatory-role-of-pain-related-affective-distress
#2
Kara Manning, Andrew H Rogers, Jafar Bakhshaie, Julianna B D Hogan, Julia D Buckner, Joseph W Ditre, Michael J Zvolensky
Rates of cannabis use and related problems continue to rise, ranking as the third most common substance use disorder in the United States, behind tobacco and alcohol use. Past work suggests that perceived distress tolerance is related to several clinically significant features of cannabis use (e.g., coping-oriented use). However, there has been little exploration of the mechanisms that may underlie relations between perceived distress tolerance and cannabis use problems, withdrawal severity, and self-efficacy for quitting...
May 19, 2018: Addictive Behaviors
https://www.readbyqxmd.com/read/29787293/compulsive-sexual-behavior-a-twelve-step-therapeutic-approach
#3
Yaniv Efrati, Mateusz Gola
Background and aims Sexuality is natural to human life and inseparable from it, yet some individuals develop compulsive sexual behavior (CSB). Many individuals with CSB seek treatment in free self-support groups based on the twelve-step program. This program was extensively studied in substance abuse disorders (e.g., Alcoholics Anonymous), but little is known about its efficiency in CSB. Methods We "assesed" questionnaire data on sociodemographical-, psychological-, and recovery-related factors from 97 male participants of Sexaholics Anonymous (SA) programs in Israel...
May 22, 2018: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/29786898/adults-with-comorbid-posttraumatic-stress-disorder-alcohol-use-disorder-and-opioid-use-disorder-the-effectiveness-of-modified-prolonged-exposure
#4
Kelly R Peck, Julie A Schumacher, Paul R Stasiewicz, Scott F Coffey
Opioid use disorders (OUDs) are a growing problem in the United States. When OUDs co-occur with problematic drinking and posttraumatic stress disorder (PTSD), negative drug-related mental and physical health outcomes may be exacerbated. Thus, it is important to establish whether PTSD treatments with established efficacy for dually diagnosed individuals also demonstrate efficacy in individuals who engage in problematic drinking and concurrent opioid misuse. Adults who met DSM-IV-TR criteria for PTSD and alcohol dependence were recruited from a substance use treatment facility and were randomly assigned to receive either modified prolonged exposure (mPE) therapy for PTSD or a non-trauma-focused comparison treatment...
May 22, 2018: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/29781886/axis-ii-personality-disorders-are-linked-to-an-adverse-course-of-bipolar-disorder
#5
Robert M Post, Susan McElroy, Ralph Kupka, Trisha Suppes, Gerhard Hellemann, Willem Nolen, Mark Frye, Paul Keck, Heinz Grunze, Michael Rowe
The relationship of personality disorder (PD) psychopathology to the course of bipolar disorder remains inadequately described. After giving informed consent, more than 782 outpatients with bipolar disorder rated themselves on the 99-item Personality Disorder Questionnaire, Version 4 (PDQ4) when depressed or euthymic. They also rated six poor prognosis factors (PPFs). The relationships of the PPFs to the total PDQ4 score were examined by a linear regression. Even after correcting for the higher PDQ4 scores observed when patients were suffering depression, the PDQ4 was significantly related to a history of child abuse, early age of onset, an anxiety disorder comorbidity, rapid cycling, and 20 or more previous episodes, but not substance abuse...
May 17, 2018: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/29781639/tobacco-use-and-smoking-behaviors-of-individuals-with-a-serious-mental-illness
#6
Donna Pettey, Tim Aubry
OBJECTIVES: The purpose of this study was to determine the prevalence of tobacco use and overall smoking behaviors within a sample of individuals with a serious mental illness who were homeless or vulnerably housed and receiving community mental health services. METHODS: In 2010, individuals (N = 639) were interviewed, and identified smokers completed the Fagerström Test for Nicotine Dependence (FTND) and additional questions related to their smoking behaviors...
May 21, 2018: Psychiatric Rehabilitation Journal
https://www.readbyqxmd.com/read/29780355/therapeutic-interference-with-vascular-calcification-lessons-from-klotho-hypomorphic-mice-and-beyond
#7
REVIEW
Florian Lang, Christina Leibrock, Lisann Pelzl, Meinrad Gawaz, Burkert Pieske, Ioana Alesutan, Jakob Voelkl
Medial vascular calcification, a major pathophysiological process associated with cardiovascular disease and mortality, involves osteo-/chondrogenic transdifferentiation of vascular smooth muscle cells (VSMCs). In chronic kidney disease (CKD), osteo-/chondrogenic transdifferentiation of VSMCs and, thus, vascular calcification is mainly driven by hyperphosphatemia, resulting from impaired elimination of phosphate by the diseased kidneys. Hyperphosphatemia with subsequent vascular calcification is a hallmark of klotho-hypomorphic mice, which are characterized by rapid development of multiple age-related disorders and early death...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29779550/peer-workers-in-the-behavioral-and-integrated-health-workforce-opportunities-and-future-directions
#8
Cheryl A Gagne, Wanda L Finch, Keris J Myrick, Livia M Davis
The growth of the peer workforce in behavioral health services is bringing opportunities to organizations and institutions that serve people living with mental and substance use disorders and their families. Peer workers are defined as people in recovery from mental illness or substance use disorders or both that possess specific peer support competencies. Similar roles are identified for families of people in recovery. Peer support has been implemented in a vast range of behavioral health services, including in the relatively new use of peer support in criminal justice and emergency service environments...
June 2018: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29779227/risk-profile-of-young-people-admitted-to-hospital-for-suicidal-behaviour-in-melbourne-australia
#9
Rohan Borschmann, Patrick Stark, Chidambaram Prakash, Susan M Sawyer
AIM: Self-harm and suicidal behaviour is most prevalent during adolescence, but little is known about the risk profile of adolescents admitted to hospital for suicidal behaviour. Young people who self-harm are at an increased risk of mortality compared to those who do not self-harm; adolescents admitted to hospital for suicidal behaviour are particularly at risk. The aim of this study was to generate a risk profile of adolescents admitted to hospital with suicidal behaviour. METHODS: We conducted a 12-month retrospective audit of adolescent admissions to the mental health inpatient unit at a tertiary children's hospital in Melbourne, Australia...
May 20, 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29778929/anxiety-sensitivity-in-the-association-between-posttraumatic-stress-and-substance-use-disorders-a-systematic-review
#10
REVIEW
Anka A Vujanovic, Samantha G Farris, Brooke A Bartlett, Robert C Lyons, Moira Haller, Peter J Colvonen, Sonya B Norman
Posttraumatic stress disorder (PTSD) and substance use disorders (SUD) are complex psychiatric conditions that commonly co-occur. No evidence-based, "gold standard" treatments for PTSD/SUD comorbidity are currently available. Thus, it is imperative to better understand cognitive-affective mechanisms, targetable via cognitive-behavioral intervention (i.e., malleable), that may be related to both disorders in order to improve the theory and treatment of PTSD/SUD. Anxiety sensitivity is a malleable cognitive-affective factor with relevance to both PTSD and SUD...
May 17, 2018: Clinical Psychology Review
https://www.readbyqxmd.com/read/29776789/transdiagnostic-effects-of-ventromedial-prefrontal-cortex-transcranial-magnetic-stimulation-on-cue-reactivity
#11
Tonisha E Kearney-Ramos, Logan T Dowdle, Daniel H Lench, Oliver J Mithoefer, William H Devries, Mark S George, Raymond F Anton, Colleen A Hanlon
BACKGROUND: Elevated frontal and striatal reactivity to drug cues is a transdiagnostic hallmark of substance use disorders. The goal of these experiments was to determine if it is possible to decrease frontal and striatal reactivity to drug cues in both cocaine users and heavy alcohol users through continuous theta burst stimulation (cTBS) to the left ventromedial prefrontal cortex (VMPFC). METHODS: Two single-blinded, within-subject, active sham-controlled experiments were performed wherein neural reactivity to drug/alcohol cues versus neutral cues was evaluated immediately before and after receiving real or sham cTBS (110% resting motor threshold, 3600 pulses, Fp1 location; N = 49: 25 cocaine users [experiment 1], 24 alcohol users [experiment 2]; 196 total functional magnetic resonance imaging scans)...
April 10, 2018: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/29776355/can-deep-transcranial-magnetic-stimulation-dtms-be-used-to-treat-substance-use-disorders-sud-a-systematic-review
#12
Karina Karolina Kedzior, Imke Gerkensmeier, Maria Schuchinsky
BACKGROUND: Deep transcranial magnetic stimulation (DTMS) is a non-invasive method of stimulating widespread cortical areas and, presumably, deeper neural networks. The current study assessed the effects of DTMS in the treatment of substance use disorders (SUD) using a systematic review. METHODS: Electronic literature search (PsycInfo, Medline until April 2017) identified k = 9 studies (k = 4 randomized-controlled trials, RCTs, with inactive sham and k = 5 open-label studies)...
May 18, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29775957/how-treatment-improvement-in-adhd-and-cocaine-dependence-are-related-to-one-another-a-secondary-analysis
#13
Frances R Levin, C Jean Choi, Martina Pavlicova, John J Mariani, Amy Mahony, Daniel J Brooks, Edward V Nunes, John Grabowski
BACKGROUND: Attention-deficit hyperactivity disorder (ADHD) is overrepresented among individuals seeking treatment for substance use disorders. We previously reported that treatment with extended release mixed amphetamine salts (MAS-XR) increased abstinence, compared to placebo, among patients with co-occurring ADHD and cocaine dependence. This secondary analysis investigates the temporal relationship between ADHD improvement and cocaine abstinence in the first six weeks of the trial...
May 1, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29775870/adverse-and-adaptive-childhood-experiences-are-associated-with-parental-reflective-functioning-in-mothers-with-substance-use-disorder
#14
Ulrika Håkansson, Reidulf Watten, Kerstin Söderström, Finn Skårderud, Merete Glenne Øie
Mothers with a substance use disorder (SUD) are at risk for maladaptive parenting practices, and have heightened likelihood of having experienced childhood adversity themselves. In addition, parental reflective functioning (PRF), a capacity underlying sensitive caregiving, is often low in mothers with SUD. This study examines the relationship between PRF and aversive (emotional, physical, sexual abuse and neglect) and adaptive (safety and competence) experiences, in different developmental phases (early childhood, latency, and adolescence) in mothers with a SUD...
May 15, 2018: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29771745/national-institute-on-drug-abuse-international-program-improving-opioid-use-disorder-treatment-through-international-research-training
#15
Steven W Gust, Judy McCormally
PURPOSE OF REVIEW: For more than 25 years, the National Institute on Drug Abuse (NIDA) has supported research-training programs, establishing a global research network and expanding the knowledge base on substance use disorders. International research to inform approaches to opioid addiction is particularly important and relevant to the United States, where opioid misuse, addiction, and overdose constitute an emerging public health crisis. This article summarizes the NIDA International Program and illustrates its impact by reviewing recent articles about treatment approaches for opioid use disorders (OUD)...
May 15, 2018: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/29771559/body-mass-index-across-adolescence-and-substance-use-problems-in-early-adulthood
#16
Ashley N Gearhardt, Rebecca Waller, Jennifer M Jester, Luke W Hyde, Robert A Zucker
Excessive substance use and obesity are underpinned by a number of shared risk factors (e.g., reward dysfunction, impulsivity). Food and drugs of abuse engage similar reward-related neural circuitry and the food-drug competition hypothesis proposes that excess consumption of food may diminish desire for drugs of abuse by competing for neural receptors associated with reward and motivation. Adolescence is a high-risk period for both increased substance use and excessive weight gain. In the present study, the authors tested whether, consistent with the food-drug competition hypothesis, elevated body mass index (BMI) across adolescence predicted fewer substance use problems in young adulthood...
May 2018: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
https://www.readbyqxmd.com/read/29770947/when-marijuana-is-used-before-cigarettes-or-alcohol-demographic-predictors-and-associations-with-heavy-use-cannabis-use-disorder-and-other-drug-related-outcomes
#17
Brian J Fairman, C Debra Furr-Holden, Renee M Johnson
Recent loosening of state and federal policy restrictions on marijuana, along with changes in social norms regarding marijuana use and decreases in prevalence of other types of substance use, may lead to increases in youth initiating marijuana before other types of substances such as alcohol and tobacco. We investigated predictors and potential consequences of initiating marijuana before other drugs for youth aged 12-21-years in the USA. Nationally representative, cross-sectional survey data from the US National Survey on Drug Use and Health supplied self-reported age of first marijuana, cigarettes, alcohol, other tobacco, and other illegal drug use among 12-21-year-old samples from 2004 to 2014 (n = 275,559)...
May 17, 2018: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/29764602/psychiatric-disorders-among-people-living-with-hiv-aids-in-iran-prevalence-severity-service-utilization-and-unmet-mental-health-needs
#18
Behrang Shadloo, Masoumeh Amin-Esmaeili, Abbas Motevalian, Minoo Mohraz, Abbas Sedaghat, Mohammad Mehdi Gouya, Afarin Rahimi-Movaghar
BACKGROUND: HIV and psychiatric disorders are closely correlated and are accompanied by some similar risk factors. OBJECTIVE: The aim of this study was to assess psychiatric comorbidity and health service utilization for mental problems among people living with HIV/AIDS in Iran. METHODS: A total of 250 cases were randomly selected from a large referral center for HIV treatment and care in Tehran, Iran. Psychiatric disorders in the past 12 months including mood, anxiety, and substance use disorders were assessed through face-to-face interview, using a validated Persian translation of the Composite International Diagnostic Interview (CIDI v2...
July 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29761131/depression-and-anxiety-among-patients-on-chronic-opioid-therapy
#19
Muhamad Y Elrashidi, Lindsey M Philpot, Priya Ramar, William B Leasure, Jon O Ebbert
Background: Chronic noncancer pain (CNCP) and chronic opioid therapy (COT) commonly coexist with comorbid depression and anxiety. We investigated the prevalence of depression and anxiety and their correlates at the time of controlled substance agreement (CSA) enrollment among patients with CNCP and a history of depression or anxiety on COT. Methods: Retrospective analysis of 1066 patients in a Midwest primary care practice enrolled in CSAs for COT between May 9, 2013, and August 15, 2016...
January 2018: Health Services Research and Managerial Epidemiology
https://www.readbyqxmd.com/read/29760674/validation-of-a-spanish-questionnaire-on-mobile-phone-abuse
#20
María A Olivencia-Carrión, Isabel Ramírez-Uclés, Pablo Holgado-Tello, Francisca López-Torrecillas
Mobile phone addiction has attracted much attention recently and is showing similarity to other substance use disorders. Because no studies on mobile phone addiction had yet been conducted in Spain, we developed and validated a questionnaire (Cuestionario de Abuso del Teléfono Móvil, ATeMo) to measure mobile phone abuse among young adults in Spanish. The ATeMo questionnaire was designed based on relevant DSM-5 diagnostic criteria and included craving as a diagnostic symptom. Using stratified sampling, the ATeMo questionnaire was administered to 856 students (mean age 21, 62% women)...
2018: Frontiers in Psychology
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