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https://www.readbyqxmd.com/read/29145529/volumetric-bone-measurement-around-dental-implants-using-3d-image-superimposition-a-methodological-and-clinical-pilot-study
#1
Eduardo Aydos Villarinho, André Correia, Alvaro Vigo, Nuno Viriato Ramos, Mário Augusto Pires Vaz, Rosemary Sadami Arai Shinkai
PURPOSE: This study describes the development of a methodology for using three-dimensional (3D) image superimposition to measure volumetric changes in bone level around dental implants in comparison with linear measures. MATERIALS AND METHODS: The sample was comprised of 46 dental implants of 6-mm length and 4.1-mm diameter placed in the posterior maxilla and posterior mandible in 20 patients. All implants received screw-retained single crowns. Radiographic images were taken using cone beam computed tomography (CBCT) and digital periapical radiography after implantation and after 12 and 24 months of functional loading (after crown installation)...
November 16, 2017: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/29144073/evaluation-of-certain-food-additives
#2
(no author information available yet)
This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of various food additives, including flavouring agents, with a view to concluding as to safety concerns and to preparing specifications for identity and purity. The first part of the report contains a general discussion of the principles governing the toxicological evaluation of and assessment of dietary exposure to food additives, including flavouring agents. A summary follows of the Committee’s evaluations of technical, toxicological and dietary exposure data for 10 food additives (Allura Red AC; carob bean gum; lutein esters from Tagetes erecta; octenyl succinic acid (OSA)– modified gum arabic; pectin; Quinoline Yellow; rosemary extract; steviol glycosides; tartrazine; and xanthan gum) and five groups of flavouring agents (alicyclic, alicyclic-fused and aromatic-fused ring lactones; aliphatic and aromatic amines and amides; aliphatic secondary alcohols, ketones and related esters; cinnamyl alcohol and related substances; and tetrahydrofuran and furanone derivatives)...
2017: World Health Organization Technical Report Series
https://www.readbyqxmd.com/read/29143699/are-there-distinct-cognitive-and-motivational-sub-groups-of-children-with-adhd
#3
Rikke Lambek, Edmund Sonuga-Barke, Rosemary Tannock, Anne Virring Sørensen, Dorte Damm, Per Hove Thomsen
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is proposed to be a neuropsychologically heterogeneous disorder that encompasses two distinct sub-groups, one with executive function (EF) deficits and one with delay aversion (DA). However, such claims have often been based on studies that have operationalized neuropsychological deficits using a categorical approach - using intuitive but rather arbitrary, clinical cut-offs. The current study applied an alternative empirical approach to sub-grouping in ADHD, latent profile analysis (LPA), and attempted to validate emerging subgroups through clinically relevant correlates...
November 16, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/29140554/factors-associated-to-oral-health-related-quality-of-life-in-patients-with-diabetes
#4
Sylvie Azogui-Lévy, Rosemary Dray-Spira, Sarah Attal, Agnes Hartemann, Fani Anagnostou, Jean Azerad
AIMS: Oral pathologies are prevalent in diabetes, and they may affect the quality of life and patient's perception of their oral health. The aim of this study was to investigate the factors associated to oral health-related quality of life of patients with diabetes. METHODS: A cross-sectional study was conducted involving 316 patients visiting a hospital diabetic unit. Sociodemographic, oral and medical care data were recorded, and a General Oral Health Assessment Index (GOHAI) questionnaire was completed...
November 15, 2017: Australian Dental Journal
https://www.readbyqxmd.com/read/29138031/mortality-and-pulmonary-outcomes-of-extremely-preterm-infants-exposed-to-antenatal-corticosteroids
#5
Colm P Travers, Waldemar A Carlo, Scott A Mcdonald, Abhik Das, Edward F Bell, Namasivayam Ambalavanan, Alan H Jobe, Ronald N Goldberg, Carl T D'Angio, Barbara J Stoll, Seetha Shankaran, Abbot R Laptook, Barbara Schmidt, Michele C Walsh, Pablo J Sanchez, M Bethany Ball, Ellen C Hale, Nancy S Newman, Rosemary D Higgins
BACKGROUND: Antenatal corticosteroids are given primarily to induce fetal lung maturation but results from meta-analyses of randomized controlled trials have not shown mortality or pulmonary benefits for extremely preterm infants although these are the infants most at risk of mortality and pulmonary disease. OBJECTIVE: To determine if exposure to antenatal corticosteroids is associated with a lower rate of death and pulmonary morbidities by 36 weeks' postmenstrual age...
November 11, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29137934/the-notch-pathway-is-activated-in-neoplastic-progression-in-esophageal-squamous-cell-carcinoma
#6
Daniel Lubin, Rosemarie Mick, Stuti G Shroff, Kristen Stashek, Emma Furth
The Notch signaling pathway is integral to normal human development and homeostasis and has a deterministic function on cell differentiation. Recent studies suggest aberrant Notch signaling may contribute to neoplastic progression by an increase in stem cell survival, chemoresistance, and the promotion of epithelial to mesenchymal transition. The goals of our study were to determine, utilizing quantitative technologies, the expression of activated Notch 1 in esophageal squamous cell carcinoma (SCC) and to determine the relationship between Notch 1 expression and various clinicopathologic parameters...
November 11, 2017: Human Pathology
https://www.readbyqxmd.com/read/29137560/randomized-trial-of-interventions-for-smoking-cessation-among-medicaid-beneficiaries-with-mental-illness
#7
Mary F Brunette, Sarah I Pratt, Stephen J Bartels, Emily A Scherer, Stacey C Sigmon, Joelle C Ferron, Meghan Santos, Gail E Williams, Samuel Kosydar, Rosemarie S Wolfe, Doris Lotz, Kelley Capuchino
OBJECTIVE: Medicaid beneficiaries with severe mental illnesses are a financially disadvantaged group with high rates of smoking and poor cessation outcomes. This study examined whether abstinence-contingent monetary incentives improved outcomes when added to cessation treatments at community mental health centers: prescriber visit for pharmacotherapy only (PV only), prescriber visit and facilitated quitline (PV+Q), and prescriber visit and telephone cognitive-behavioral therapy (PV+CBT)...
November 15, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/29134782/determination-of-the-clean-up-efficiency-of-the-solid-phase-extraction-of-rosemary-extracts-application-of-full-factorial-design-in-hyphenation-with-gaussian-peak-fit-function
#8
Florian Meischl, Christian G Kirchler, Michael A Jäger, Christian W Huck, Matthias Rainer
We present a novel method for the quantitative determination of the clean-up efficiency to provide a calculated parameter for peak purity through iterative fitting in conjunction with design of experiments. Rosemary extracts were used and analyzed before and after solid-phase extraction using a self-fabricated mixed-mode sorbent based on poly(N-vinylimidazole/ethylene glycol dimethacrylate). Optimization was performed by variation of washing steps using a full three-level factorial design and response surface methodology...
November 14, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/29133595/targeted-next-gen-sequencing-for-detecting-mll-gene-fusions-in-leukemia
#9
Sadia Afrin, Christine Rc Zhang, Claus Meyer, Caedyn L Stinson, Thy Pham, Timothy Jc Bruxner, Nicola C Venn, Toby N Trahair, Rosemary Sutton, Rolf Marschalek, J Lynn Fink, Andrew S Moore
Mixed Lineage Leukemia (MLL) gene rearrangements characterize approximately 70% of infant and 10% of adult and therapy-related leukemia. Conventional clinical diagnostics, including cytogenetics and fluorescence in situ hybridization (FISH) fail to detect MLL translocation partner genes (TPGs) in many patients. Long-Distance Inverse (LDI)-PCR, the 'gold standard' technique that is used to characterize MLL breakpoints is laborious and requires a large input of genomic DNA (gDNA). To overcome the limitations of current techniques, a targeted Next-Generation Sequencing (NGS) approach that requires low RNA input was tested...
November 13, 2017: Molecular Cancer Research: MCR
https://www.readbyqxmd.com/read/29132100/comparison-of-microsphere-penetration-with-lc-bead-lumi%C3%A2-versus-other-commercial-microspheres
#10
Marcus Caine, Xunli Zhang, Martyn Hill, Wei Guo, Koorosh Ashrafi, Zainab Bascal, Hugh Kilpatrick, Anthony Dunn, David Grey, Rosemary Bushby, Andrew Bushby, Sean L Willis, Matthew R Dreher, Andrew L Lewis
The purpose of this study was to evaluate LC Bead LUMI™ (40-90µm and 70-150µm) in order to determine if their increased resistance to compression influences microsphere penetration and distribution compared to more compressible commercial microspheres. LC Bead LUMI™ 40-90µm and 70-150µm, LC BeadM1(®) 70-150µm, Embozene™ 40µm and Embozene™ 100µm size and distributions were measured using optical microscopy. Penetration in vitro was evaluated using an established 'plate model', consisting of a calibrated tapered gap between a glass plate and plastic housing to allow visual observation of microsphere penetration depth...
October 31, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29131825/a-model-based-clustering-method-to-detect-infectious-disease-transmission-outbreaks-from-sequence-variation
#11
Rosemary M McCloskey, Art F Y Poon
Clustering infections by genetic similarity is a popular technique for identifying potential outbreaks of infectious disease, in part because sequences are now routinely collected for clinical management of many infections. A diverse number of nonparametric clustering methods have been developed for this purpose. These methods are generally intuitive, rapid to compute, and readily scale with large data sets. However, we have found that nonparametric clustering methods can be biased towards identifying clusters of diagnosis-where individuals are sampled sooner post-infection-rather than the clusters of rapid transmission that are meant to be potential foci for public health efforts...
November 13, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/29131407/posttraumatic-stress-disorder-gender-and-risk-factors-world-trade-center-tower-survivors-10-to-11-years-after-the-september-11-2001-attacks
#12
Rosemarie M Bowler, Shane W Adams, Vihra V Gocheva, Jiehui Li, Donna Mergler, Robert Brackbill, James E Cone
Ten to eleven years after the September 11, 2001 terrorist attacks, probable posttraumatic stress disorder (PTSD) was evaluated in 1,755 World Trade Center (WTC) evacuees based on data from the WTC Health Registry. Characteristics of men and women were compared and factors associated with PTSD symptom severity were examined using the PTSD Checklist (PCL). Compared with men (n = 1,015, 57.8%), women (n = 740, 42.2%) were younger and of lower socioeconomic status. Ten to eleven years after September 11, 2001, 13...
November 13, 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/29129385/effect-directed-fingerprints-of-77-botanical-extracts-via-a-generic-high-performance-thin-layer-chromatography-method-combined-with-assays-and-mass-spectrometry
#13
S Krüger, L Hüsken, R Fornasari, I Scainelli, G E Morlock
Quantitative effect-directed profiles of 77 industrially and freshly extracted botanicals like herbs, spices, vegetables and fruits, widely used as food ingredients, dietary supplements or traditional medicine, gave relevant information on their quality. It allows the assessment of food, dietary supplements and phytomedicines with regard to potential health-promoting activities. In contrary to sum parameter assays and targeted analysis, chromatography combined with effect-directed analysis allows fast assignment of single active compounds and evaluation of their contribution to the overall activity, originating from a food or botanical sample...
October 29, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29129184/identifying-attributes-of-care-that-may-improve-cost-effectiveness-in-the-youth-mental-health-service-system
#14
Matthew P Hamilton, Sarah E Hetrick, Cathrine Mihalopoulos, David Baker, Vivienne Browne, Andrew M Chanen, Kerryn Pennell, Rosemary Purcell, Heather Stavely, Patrick D McGorry
OBJECTIVE: To identify attributes of youth mental health care for which there is evidence of potential cost-effectiveness. STUDY DESIGN: We performed a literature review of economic evaluations that examined both costs and outcomes for attributes of youth mental health care other than pharmacological or individual psychological therapies for full-threshold disorders. DATA SOURCES: We searched the United Kingdom National Health Service Economic Evaluations Database for evaluations published to the end of 2014; and MEDLINE, Google Scholar and the citation lists of relevant publications for peer-reviewed studies published in English since 1997...
November 20, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/29129183/targeting-mental-health-care-attributes-by-diagnosis-and-clinical-stage-the-views-of-youth-mental-health-clinicians
#15
Matthew P Hamilton, Sarah E Hetrick, Cathrine Mihalopoulos, David Baker, Vivienne Browne, Andrew M Chanen, Kerryn Pennell, Rosemary Purcell, Heather Stavely, Patrick D McGorry
OBJECTIVES: To explore the potential utility of clinical stage and mental disorder categories as a basis for determining which attributes of youth mental health care should be offered to which groups of young people. METHODS: In June 2017, we conducted an online survey of youth mental health clinicians that collected information on the participants' background and areas of expertise, then presented vignettes describing young people with different stages of six mental disorders (disorder-based vignettes were matched to participants' area of expertise)...
November 20, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/29128160/prone-sleeping-position-in-infancy-implications-for-cardiovascular-and-cerebrovascular-function
#16
REVIEW
Kelsee L Shepherd, Stephanie R Yiallourou, Rosemary S C Horne, Flora Y Wong
Advances in neonatal care have improved the survival rates of preterm infants, however, the likelihood of brain injury and neurodevelopmental disability remains a significant problem. Whilst the etiology of preterm brain injury is complex, impairments in the cardio- and cerebro-vascular function have been implicated. During infancy, sleep is vital for brain development. However, instabilities in cardio- and cerebro-vascular function are most marked during sleep. Sleeping position is an important part of a safe sleeping environment...
October 13, 2017: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/29127137/ethics-of-treatment-interruption-trials-in-hiv-cure-research-addressing-the-conundrum-of-risk-benefit-assessment
#17
Gail E Henderson, Holly L Peay, Eugene Kroon, Rosemary Jean Cadigan, Karen Meagher, Thidarat Jupimai, Adam Gilbertson, Jill Fisher, Nuchanart Q Ormsby, Nitiya Chomchey, Nittaya Phanuphak, Jintanat Ananworanich, Stuart Rennie
Though antiretroviral therapy is the standard of care for people living with HIV, its treatment limitations, burdens, stigma and costs lead to continued interest in HIV cure research. Early-phase cure trials, particularly those that include analytic treatment interruption (ATI), involve uncertain and potentially high risk, with minimal chance of clinical benefit. Some question whether such trials should be offered, given the risk/benefit imbalance, and whether those who choose to participate are acting rationally...
November 10, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/29126207/effects-of-30-and-50-cigarette-pack-graphic-warning-labels-on-visual-attention-negative-affect-quit-intentions-and-smoking-susceptibility-among-disadvantaged-populations-in-the-united-states
#18
Chris Skurka, Deena Kemp, Julie Davydova, James F Thrasher, Sahara Byrne, Amelia Greiner Safi, Rosemary J Avery, Michael C Dorf, Alan D Mathios, Leah Scolere, Jeff Niederdeppe
Introduction: Though the WHO Framework Convention for Tobacco Control (FCTC) calls for the implementation of large graphic warning labels on cigarette boxes (GWLs), the courts have blocked the implementation of 50% labels in the U.S. We conducted an experiment to explore whether changing the size of GWLs is associated with changes in visual attention, negative affect, risk beliefs, and behavioral intentions. Method: We recruited adult smokers (N = 238) and middle-school youth (N = 237) throughout New York state in May 2016...
November 4, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29125394/knowledge-gained-and-retained-from-a-video-centered-community-based-intervention-for-ebola-prevention-congo
#19
Amira A Roess, Rosemarie Di Peppi, Eric A Kinzoni, Michaelle Molouania, Emily Kennedy, Saturnin R Ibata, Nkenda Badinga, Fredy S Mabola, Cynthia Moses
There are few effective communication interventions to respond to Ebola Virus Disease (EVD) outbreaks, and their development is a continuing challenge. The largest outbreak of EVD was first recognized in 2014 and once again highlighted the need for health education communication campaigns. EVD emergence and transmission are associated with behaviors that increase exposure to infected individuals and infected wildlife. In 2008-2009, an educational video-centered intervention consisting of a film followed by a structured discussion was developed to improve EVD knowledge, attitudes, and behaviors (KABs) for prevention of EVD and care of infected people...
November 10, 2017: Journal of Health Communication
https://www.readbyqxmd.com/read/29122832/fifteen-minute-consultation-a-child-with-a-suspected-drug-allergy
#20
Peishan Wu, Katherine Longbottom, Rosemary Hague, Gillian Vance
Adverse drug reactions are common in children, but true drug allergy is rare. It can be difficult to determine whether signs such as skin rashes are caused by the underlying illness or medications prescribed. Accurate diagnosis is important for patient safety and optimal treatment. We review the presentation of drug allergy and discuss current management options for children.
November 9, 2017: Archives of Disease in Childhood. Education and Practice Edition
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