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https://www.readbyqxmd.com/read/29137667/selective-medial-soft-tissue-release-combined-with-tibial-reduction-osteotomy-in-total-knee-arthroplasty
#1
Qian Tang, Hua-Chen Yu, Ping Shang, Shang-Kun Tang, Hua-Zi Xu, Hai-Xiao Liu, Yu Zhang
BACKGROUND: To obtain the correct coronal alignment and balancing in flexion and extension, we established a selective medial release technique and investigated the effectiveness and safety of the technique during primary total knee arthroplasty (TKA). METHODS: Four hundred sixty-six primary TKAs with varus deformity were prospectively evaluated between June 2013 and June 2015. A knee joint position similar to Patrick's sign was used to release the medial structure...
November 14, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29136938/temperature-phased-anaerobic-digestion-of-food-waste-a-comparison-with-single-stage-digestions-based-on-performance-and-energy-balance
#2
Benyi Xiao, Yu Qin, Wenzhe Zhang, Jing Wu, Hong Qiang, Junxin Liu, Yu-You Li
The temperature-phased anaerobic digestion (TPAD) of food waste was studied for the purpose of comparing with single-stage mesophilic and thermophilic anaerobic digestion. The biogas and methane yields in the TPAD during the steady period were 0.759 ± 0.115 L/g added VS and 0.454 ± 0.201 L/g added VS, which were lower than those in the two single-stage anaerobic digestion. The improper sludge retention time may be the reason for the lower biogas and methane production in TPAD. The removal of volatile solids in the TPAD was 78...
October 26, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29135427/effect-of-bathroom-aids-and-age-on-balance-control-during-bathing-transfers
#3
Emily C King, Alison C Novak
Bathroom assistive devices are used to improve safety during bathing transfers, but biomechanical evidence to support clinical recommendations is lacking. This study evaluated the effectiveness of common bathroom aids in promoting balance control during bathing transfers. Twenty-six healthy adults (12 young, 14 older) stepped into and out of a slippery bathtub while using a vertical grab bar on the side wall, a horizontal grab bar on the back wall, a bath mat, a side wall touch, or no assistance. Balance control was characterized using center of pressure measures and showed greater instability for older adults...
November 2017: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
https://www.readbyqxmd.com/read/29134532/a-robust-multi-objective-bargaining-methodology-for-inter-basin-water-resource-allocation-a-case-study
#4
Omid Nasiri-Gheidari, Safar Marofi, Farzaneh Adabi
In this study, a new methodology is proposed to balance environmental and economic issues in water allocation under uncertainty. Two objective functions, including maximizing economic income (EI) and minimizing environmental pollution (EP), were considered as two groups of players to construct a deterministic multi-objective bargaining methodology (DMOBM). In the next step, it is enhanced to a robust multi-objective bargaining methodology (RMOBM), which is capable of incorporating the main uncertainties exist in the problem...
November 14, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29130977/effects-of-wearable-sensor-based-balance-and-gait-training-on-balance-gait-and-functional-performance-in-healthy-and-patient-populations-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#5
Katharina Gordt, Thomas Gerhardy, Bijan Najafi, Michael Schwenk
BACKGROUND: Wearable sensors (WS) can accurately measure body motion and provide interactive feedback for supporting motor learning. OBJECTIVE: This review aims to summarize current evidence for the effectiveness of WS training for improving balance, gait and functional performance. METHODS: A systematic literature search was performed in PubMed, Cochrane, Web of Science, and CINAHL. Randomized controlled trials (RCTs) using a WS exercise program were included...
November 1, 2017: Gerontology
https://www.readbyqxmd.com/read/29128629/influence-of-emotional-stimuli-on-lower-limb-cutaneous-reflexes-during-human-gait
#6
Martin Zaback, Brian C Horslen, Taylor W Cleworth, Laurel Collins, Cécile Langlet, J Timothy Inglis, Mark G Carpenter
Previous research has shown that cutaneous reflexes are modulated when walking with a threat to stability. It is unclear if this reflex modulation is purely related to the context of the imposed threat or if emotional changes associated with the threat exert an independent influence on reflex excitability. This study investigated the influence of emotional stimuli on lower limb cutaneous reflexes during treadmill walking. Twenty-eight healthy young adults walked at a self-selected pace while viewing pictures that manipulated emotional arousal and valence (confirmed with electrodermal and self-report measures)...
November 8, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/29127210/hiv-1-nc-induced-stress-granule-assembly-and-translation-arrest-are-inhibited-by-the-dsrna-binding-protein-staufen1
#7
Shringar Rao, Alessandro Cinti, Abdelkrim Temzi, Raquel Amorim, Ji Chang You, Andrew J Mouland
The nucleocapsid (NC) is an N-terminal protein derived from the HIV-1 Gag precursor polyprotein, pr55Gag. NC possesses key functions at several pivotal stages of viral replication. For example, an interaction between NC and the host, double-stranded RNA-binding protein Staufen1 was shown to regulate several steps in the viral replication cycle, such as Gag multimerisation and genomic RNA encapsidation. In this work, we observed that the overexpression of NC leads to the induction of stress granule (SG) assembly...
November 10, 2017: RNA
https://www.readbyqxmd.com/read/29124479/study-on-the-computer-aided-design-of-high-energetic-compounds-based-on-the-1-2-3-4-tetrazine-1-3-dioxide-frame
#8
Wei-Peng Lai, Tao Yu, Ying-Zhe Liu, Yi-Ding Ma, Peng Lian, Zhong-Xue Ge, Jian Lv
In order to discover more potential high energy compounds, five computer-aided design methods were founded, and 20 high energetic compounds based on the 1,2,3,4-tetrazine-1,3-dioxide frame were designed. The first step of computer-aided design methods was to design new frame M. Three combination rules were invented, they were simple double-points rule, complicated double-points rule, and complicated multi-points rule. The second step of computer-aided design methods was to design 1,2,3,4-tetrazine 1,3-dioxides derivants by connecting M to 1,2,3,4-tetrazine-1,3-dioxides...
November 9, 2017: Journal of Molecular Modeling
https://www.readbyqxmd.com/read/29122267/effects-of-traditional-chinese-exercises-on-the-rehabilitation-of-limb-function-among-stroke-patients-a-systematic-review-and-meta-analysis
#9
REVIEW
Li Ge, Qing-Xiang Zheng, Yan-Tan Liao, Jing-Yu Tan, Qiu-Lin Xie, Mikael Rask
OBJECTIVE: To systematically review literature about the rehabilitative effects of traditional Chinese exercises (TCEs) on limb function among patients with stroke. METHODS: Systematic review and meta-analysis of randomized controlled trials (RCTs). Twelve electronic databases were searched from their inceptions to February 2017, including PudMed, The Cochrane Library, Web of Science, EMBase, Science Direct, PsycINFO, Cumulative Index to Nursing and Allied Health Literature, Allied and Complementary Medicine, Chinese Scientific Journal Database, China National Knowledge Infrastructure, Chinese Biomedical Literature Database and WanFang Data...
November 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/29121886/the-strange-case-of-mr-h-starting-dialysis-at-90%C3%A2-years-of-age-clinical-choices-impact-on-ethical-decisions
#10
Giorgina Barbara Piccoli, Andreea Corina Sofronie, Jean-Philippe Coindre
BACKGROUND: Starting dialysis at an advanced age is a clinical challenge and an ethical dilemma. The advantages of starting dialysis at "extreme" ages are questionable as high dialysis-related morbidity induces a reflection on the cost- benefit ratio of this demanding and expensive treatment in a person that has a short life expectancy. Where clinical advantages are doubtful, ethical analysis can help us reach decisions and find adapted solutions. CASE PRESENTATION: Mr...
November 9, 2017: BMC Medical Ethics
https://www.readbyqxmd.com/read/29121491/examination-of-reactive-motor-responses-to-achilles-tendon-vibrations-during-an-inhibitory-stepping-reaction-time-task
#11
Justine Magnard, Christophe Cornu, Gilles Berrut, Thibault Deschamps
Inhibition is known to influence balance, step initiation and gait control. A specific subcomponent of inhibition, the perceptual inhibition process, has been suggested to be specifically involved in the integration of proprioceptive information that is necessary for efficient postural responses. This study aimed to investigate the inhibition requirements of planning and executing a choice step initiation task in young adults following experimental perturbation of proprioceptive information using Achilles tendon vibrations...
November 6, 2017: Human Movement Science
https://www.readbyqxmd.com/read/29114532/changes-in-physical-fitness-and-body-composition-according-to-the-physical-activities-of-korean-adolescents
#12
Minsoo Cho, Ji-Youn Kim
This study comparatively analyzed obesity, lean balance, and physical fitness related to growth and development in female middle school students to investigate the importance of regular physical activity on body composition and physical fitness in adolescence. The subjects were 31 elementary school students in grades 5-6 in Seoul, consisting of 16 students in the regularly active group and 15 students in the inactive group. Body composition and physical fitness factors were measured. Height, weight, body mass index (BMI), fat mass, and fat-free mass were measured using Inbody 3...
October 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/29113338/mir-23a-modulates-x-linked-inhibitor-of-apoptosis-mediated-autophagy-in-human-luminal-breast-cancer-cell-lines
#13
Ping Chen, Yin-Huan He, Xing Huang, Si-Qi Tao, Xiao-Nan Wang, Hong Yan, Ke-Shuo Ding, Peter E Lobie, Wen-Yong Wu, Zheng-Sheng Wu
Autophagy is a conserved multi-step lysosomal process that is induced by diverse stimuli including cellular nutrient deficiency. X-linked inhibitor of apoptosis (XIAP) promotes cell survival and recently has been demonstrated to suppress autophagy. Herein, we examined regulation of XIAP-mediated autophagy in breast cancer cells and determined the underlying molecular mechanism. To investigate this process, autophagy of breast cancer cells was induced by Earle's balanced salt solution (EBSS). We observed discordant expression of XIAP mRNA and protein in the autophagic process induced by EBSS, suggesting XIAP may be regulated at a post-transcriptional level...
October 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/29112808/comparative-analysis-of-supply-risk-mitigation-strategies-for-critical-byproduct-minerals-a-case-study-of-tellurium
#14
Michele Bustamante, Gabrielle Gaustad, Elisa Alonso
Materials criticality assessment is an analytical framework increasingly applied to identify materials of importance to stakeholders who face scarcity risks. Although criticality assessment studies highlight materials for the implicit purpose of informing future action, the aggregated nature of the studies' results make them poorly suited for use as guidance in nuanced strategy development and implementation. As a first step in the selection of mitigation strategies, the present work proposes a modeling framework and accompanying set of metrics to directly compare strategies by measuring effectiveness of risk reduction as a function of features of projected supply-demand balance over time...
November 7, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/29107061/physical-activity-and-physical-fitness-of-nursing-home-residents-with-cognitive-impairment-a-pilot-study
#15
José Marmeleira, Soraia Ferreira, Armando Raimundo
Physical activity and physical fitness are important for health, functional mobility and performance of everyday activities. To date, little attention has been given to physical activity and physical fitness among nursing home residents with cognitive impairment. Therefore, the main aim of this study was to examine physical activity behavior and physical fitness of institutionalized older adults with cognitive impairment and to investigate their interrelations. Forty-eight older adults with cognitive impairment (83...
October 31, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/29107040/longitudinal-recovery-and-reduced-costs-after-120-sessions-of-locomotor-training-for-motor-incomplete-spinal-cord-injury
#16
Sarah A Morrison, Douglas Lorenz, Carol P Eskay, Gail F Forrest, D Michele Basso
OBJECTIVE: To determine the impact of long term, body weight supported locomotor training (BWSLT) after chronic, incomplete spinal cord injury (SCI). Also, health care costs were estimated related to lost recovery potential and preventable secondary complications that may have occurred due to visit limits imposed by insurers. DESIGN: Prospective observational cohort with longitudinal follow up. SETTING: Eight outpatient rehabilitation centers that participate in the Christopher & Dana Reeve Foundation NeuroRecovery Network® (NRN)...
October 26, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29105657/gait-training-after-spinal-cord-injury-safety-feasibility-and-gait-function-following-8-weeks-of-training-with-the-exoskeletons-from-ekso-bionics
#17
Carsten Bach Baunsgaard, Ulla Vig Nissen, Anne Katrin Brust, Angela Frotzler, Cornelia Ribeill, Yorck-Bernhard Kalke, Natacha León, Belén Gómez, Kersti Samuelsson, Wolfram Antepohl, Ulrika Holmström, Niklas Marklund, Thomas Glott, Arve Opheim, Jesus Benito, Narda Murillo, Janneke Nachtegaal, Willemijn Faber, Fin Biering-Sørensen
STUDY DESIGN: Prospective quasi-experimental study, pre- and post-design. OBJECTIVES: Assess safety, feasibility, training characteristics and changes in gait function for persons with spinal cord injury (SCI) using the robotic exoskeletons from Ekso Bionics. SETTING: Nine European rehabilitation centres. METHODS: Robotic exoskeleton gait training, three times weekly over 8 weeks. Time upright, time walking and steps in the device (training characteristics) were recorded longitudinally...
November 6, 2017: Spinal Cord
https://www.readbyqxmd.com/read/29103342/glasses-type-wearable-computer-displays-usability-considerations-examined-with-a-3d-glasses-case-study
#18
Joonho Chang, Seung Ki Moon, Kihyo Jung, Wonmo Kim, Matthew Parkinson, Andris Freivalds, Timothy W Simpson, Seon Pill Baik
This study presents usabilityconsiderations and solutions for the design of glasses-type wearable computer displays and examines their effectiveness in a case study.Design countermeasures were investigated by a four-step design process: (1) preliminary design analysis;(2) design idea generation; (3) final design selection; and (4) virtual fitting trial.Three design interventionswere devised from the design process: (1) weight balance to reduce pressure concentrated on the nose, (2) compliant temples to accommodate diverse head sizes, and (3) a hanger mechanism to help spectacle users hang theirwearable display on their eye glasses...
November 6, 2017: Ergonomics
https://www.readbyqxmd.com/read/29101245/area-specific-regulation-of-quiescent-neural-stem-cells-by-notch3-in-the-adult-mouse-subependymal-zone
#19
Hiroki Kawai, Daichi Kawaguchi, Benjamin D Kuebrich, Takeo Kitamoto, Masahiro Yamaguchi, Yukiko Gotoh, Shohei Furutachi
In the adult mammalian brain, neural stem cells (NSCs) generate new neurons throughout lifetime. The balance between quiescence and active cell division among NSCs is crucial in producing appropriate numbers of neurons while maintaining the stem cell pool for a long period. The Notch signaling pathway plays a central role in both maintaining quiescent NSCs (qNSCs) and promoting cell division of active NSCs (aNSCs), although it remains elusive how this pathway regulates these apparently opposite functions. Notch1 has been shown to promote proliferation of aNSCs without affecting qNSCs in the adult mouse subependymal zone (SEZ)...
November 3, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29096923/standing-wave-design-and-optimization-of-a-simulated-moving-bed-chromatography-for-separation-of-xylobiose-and-xylose-under-the-constraints-on-product-concentration-and-pressure-drop
#20
Chung-Gi Lee, Jae-Hwan Choi, Chanhun Park, Nien-Hwa Linda Wang, Sungyong Mun
The feasibility of a simulated moving bed (SMB) technology for the continuous separation of high-purity xylobiose (X2) from the output of a β-xylosidase X1→X2 reaction has recently been confirmed. To ensure high economical efficiency of the X2 production method based on the use of xylose (X1) as a starting material, it is essential to accomplish the comprehensive optimization of the X2-separation SMB process in such a way that its X2 productivity can be maximized while maintaining the X2 product concentration from the SMB as high as possible in consideration of a subsequent lyophilization step...
October 28, 2017: Journal of Chromatography. A
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