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https://www.readbyqxmd.com/read/27815089/association-between-excessive-bmi-increase-during-puberty-and-risk-of-cardiovascular-mortality-in-adult-men-a-population-based-cohort-study
#1
Claes Ohlsson, Maria Bygdell, Arvid Sondén, Annika Rosengren, Jenny M Kindblom
BACKGROUND: Being overweight during childhood and adolescence is associated with increased risk of cardiovascular disease in adulthood, but the relative contribution of prepubertal childhood BMI and BMI change during puberty to adult mortality due to cardiovascular disease is unknown. We assessed the contribution of these two distinct developmental BMI parameters for cardiovascular mortality in adult men. METHODS: As a part of the ongoing population-based BMI Epidemiology Study (BEST) in Gothenburg, Sweden, men born between 1945 and 1961 with information on both their childhood BMI at age 8 years and BMI change during puberty were included in the study and followed up until December, 2013...
December 2016: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/27732960/selenite-promotes-all-trans-retinoic-acid-induced-maturation-of-acute-promyelocytic-leukemia-cells
#2
Sougat Misra, Arun Kumar Selvam, Marita Wallenberg, Aditya Ambati, András Matolcsy, Isabelle Magalhaes, Gilbert Lauter, Mikael Björnstedt
Selective targeting of the PML/RARα oncoprotein demonstrates a successful molecular targeted therapy in acute promyelocytic leukemia (APL) with a typical t(15:17) chromosomal translocation. The zinc-thiolate coordination is critical for structural stability of zinc finger proteins, including the PML moiety of PML/RARα. Based on the known interaction of redox-active selenium compounds with thiolate ligands of zinc, we herein have investigated the abrogatory effects of selenite alone or in combination with all-trans retinoic acid on PML/RARα and the possible effects on differentiation in these cells...
October 8, 2016: Oncotarget
https://www.readbyqxmd.com/read/27564139/gaasp-nanowires-grown-by-aerotaxy
#3
Wondwosen Metaferia, Axel R Persson, Kilian Mergenthaler, Fangfang Yang, Wei Zhang, Arkady Yartsev, Reine Wallenberg, Mats-Erik Pistol, Knut Deppert, Lars Samuelson, Martin H Magnusson
We have grown GaAsP nanowires with high optical and structural quality by Aerotaxy, a new continuous gas phase mass production process to grow III-V semiconductor based nanowires. By varying the PH3/AsH3 ratio and growth temperature, size selected GaAs1-xPx nanowires (80 nm diameter) with pure zinc-blende structure and with direct band gap energies ranging from 1.42 to 1.90 eV (at 300 K), (i.e., 0 ≤ x ≤ 0.43) were grown, which is the energy range needed for creating tandem III-V solar cells on silicon. The phosphorus content in the NWs is shown to be controlled by both growth temperature and input gas phase ratio...
September 14, 2016: Nano Letters
https://www.readbyqxmd.com/read/27450474/effects-of-alteplase-on-survival-after-ischaemic-stroke-ist-3-3-year-follow-up-of-a-randomised-controlled-open-label-trial
#4
Eivind Berge, Geoffrey Cohen, Melinda B Roaldsen, Erik Lundström, Eva Isaksson, Ann-Sofie Rudberg, Karsten Bruins Slot, John Forbes, Joel Smith, Jonathan Drever, Joanna M Wardlaw, Richard I Lindley, Peter A G Sandercock, William N Whiteley
BACKGROUND: The effect of alteplase on patient survival after ischaemic stroke is the subject of debate. We report the effect of intravenous alteplase on long-term survival after ischaemic stroke of participants in the Third International Stroke Trial (IST-3). METHODS: In IST-3, done at 156 hospitals in 12 countries (Australia, Europe, and the UK), participants (aged >18 years) were randomly assigned with a telephone voice-activated or web-based system in a 1:1 ratio to treatment with intravenous 0·9 mg/kg alteplase plus standard care or standard care alone within 6 h of ischaemic stroke...
September 2016: Lancet Neurology
https://www.readbyqxmd.com/read/27356655/endovascular-treatment-of-distal-posterior-inferior-cerebellar-artery-aneurysms
#5
Jun Tang, Linjie Wei, Lin Li, Yin Niu, Qianwei Chen, Hua Feng, Gang Zhu, Zhi Chen
OBJECTIVE: To assess the feasibility and results of endovascular treatment for ruptured distal posterior inferior cerebellar artery (PICA) aneurysms. METHODS: We retrospectively reviewed our experience and results with endovascular treatments for a series of 13 consecutive patients with ruptured distal PICA aneurysms at the Southwest Hospital, Chongqing, China, treated between June 2011 and January 2015. Therapeutic considerations, intraoperative complications, and results were evaluated...
July 2016: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/27246963/wallenberg-s-lateral-medullary-syndrome-in-an-adolescent
#6
Elizabeth Day Ruedrich, Mahesh Chikkannaiah, Gogi Kumar
No abstract text is available yet for this article.
November 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27206871/ipsilateral-hemiparesis-in-lateral-medullary-infarction-clinical-investigation-of-the-lesion-location-on-magnetic-resonance-imaging
#7
Masahiro Uemura, Hiroaki Naritomi, Hisakazu Uno, Arisa Umesaki, Kotaro Miyashita, Kazunori Toyoda, Kazuo Minematsu, Kazuyuki Nagatsuka
BACKGROUND: In 1946, Opalski reported two cases of Wallenberg syndrome with ipsilateral hemiparesis (IH). His hypothesis seems to be based on the view that IH is caused by post-decussating pyramidal tract damage. Afterwards, other researchers proposed a different hypothesis that ipsilateral sensory symptoms of limbs (ISSL) or ipsilateral limb ataxia (ILA) caused by lateral medullary infarction (LMI) might lead to ipsilateral motor weakness. The present study is aimed to clarify whether IH in LMI patients is attributable mainly to ISSL/ILA or disruption of ipsilateral post-decussating pyramidal tract...
June 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27068280/csf-and-blood-biomarkers-for-the-diagnosis-of-alzheimer-s-disease-a-systematic-review-and-meta-analysis
#8
Bob Olsson, Ronald Lautner, Ulf Andreasson, Annika Öhrfelt, Erik Portelius, Maria Bjerke, Mikko Hölttä, Christoffer Rosén, Caroline Olsson, Gabrielle Strobel, Elizabeth Wu, Kelly Dakin, Max Petzold, Kaj Blennow, Henrik Zetterberg
BACKGROUND: Alzheimer's disease biomarkers are important for early diagnosis in routine clinical practice and research. Three core CSF biomarkers for the diagnosis of Alzheimer's disease (Aβ42, T-tau, and P-tau) have been assessed in numerous studies, and several other Alzheimer's disease markers are emerging in the literature. However, there have been no comprehensive meta-analyses of their diagnostic performance. We systematically reviewed the literature for 15 biomarkers in both CSF and blood to assess which of these were most altered in Alzheimer's disease...
June 2016: Lancet Neurology
https://www.readbyqxmd.com/read/26989533/babinski-nageotte-syndrome-diagnosed-in-postpartum-period
#9
Serdar Oruç, Hayri Demirbaş, Abdullah Güzel, Mehtap Beker Acay, Mehmet Yaman
Babinski-Nageotte Syndrome (BNS) is one of the brainstem syndromes characterized by muscle weakness in the opposite half of the body with classic Wallenberg findings. According to our literature survey, only a few cases have been reported and none of them was in the postpartum period. We report a case of a typical BNS in a postpartum woman with an ischemic lesion in the medulla oblongata shown on magnetic resonance imaging.
2016: Case Reports in Neurological Medicine
https://www.readbyqxmd.com/read/26960272/-multiple-cerebral-artery-occlusion-due-to-non-bacterial-thrombotic-endocarditis-an-autopsy-case-report
#10
Yoshinari Nagakane, Hidesato Takezawa, Kanade Katsura, Yasumasa Yamamoto
A 60-year-old man was admitted to our hospital because of vertigo and repeated vomiting, which suddenly occurred 25 hours before admission. Neurologic examination revealed Wallenberg syndrome on the left side, and brain MRI showed acute infarcts in the left lateral medulla as well as in the left internal carotid artery (ICA) territory. MR angiography did not depict the left vertebral artery (VA) and the left ICA. Despite antithrombotic treatment, he developed bulbar palsy, and then, brain herniation due to infarct growth in the left middle cerebral artery territory...
2016: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/26838122/electron-microscopy-imaging-of-proteins-on-gallium-phosphide-semiconductor-nanowires
#11
Martin Hjort, Mikael Bauer, Stefan Gunnarsson, Erik Mårsell, Alexei A Zakharov, Gunnel Karlsson, Elodie Sanfins, Christelle N Prinz, Reine Wallenberg, Tommy Cedervall, Anders Mikkelsen
We have imaged GaP nanowires (NWs) incubated with human laminin, serum albumin (HSA), and blood plasma using both cryo-transmission electron microscopy and synchrotron based X-ray photoemission electron microscopy. This extensive imaging methodology simultaneously reveals structural, chemical and morphological details of individual nanowires and the adsorbed proteins. We found that the proteins bind to NWs, forming coronas with thicknesses close to the proteins' hydrodynamic diameters. We could directly image how laminin is extending from the NWs, maximizing the number of proteins bound to the NWs...
February 21, 2016: Nanoscale
https://www.readbyqxmd.com/read/26810508/two-young-stroke-patients-associated-with-regular-intravenous-immunoglobulin-ivig-therapy
#12
Yumiko Nakano, Takeshi Hayashi, Kentaro Deguchi, Kota Sato, Nozomi Hishikawa, Toru Yamashita, Yasuyuki Ohta, Yoshiki Takao, Tomohiro Morio, Koji Abe
We recently experienced 2 young adult patients who developed ischemic stroke after regular intravenous immunoglobulin (IVIg) therapy for agammaglobulinemia with diagnosis of common variable immunodeficiency (CVID) in their childhood. Patient 1 was 26-year-old woman, who developed Wallenberg's syndrome 6 days after the last IVIg therapy, but had no further stroke recurrence with cilostazol later. Patient 2 was 37-year-old man, who developed recurrent cerebral infarction in the territory of bilateral lenticulostriate branches like branch atheromatous disease (BAD) several days after the IVIg therapy...
February 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/26569158/wallenberg-syndrome-an-exceptional-cause-of-acute-vertigo-in-children
#13
Aude Ménétrey Ehresmann, Hélène Cao Van, Laura Merlini, Joel Fluss
The assessment of acute vertigo in childhood is often challenging, but fortunately a central cause is rarely identified. We present the case of a 7-year-old boy who developed, after a mild head trauma, a rotary vertigo associated with nausea and vomiting. A posttraumatic peripheral vestibular dysfunction was first suspected but not confirmed by an otoneurological evaluation. When subtle neurological signs were elicited, a brain magnetic resonance imaging was promptly requested. This showed a small infarct on the lateral posterior left part of the medulla oblongata of the brainstem, typical of Wallenberg syndrome...
January 2016: Neuropediatrics
https://www.readbyqxmd.com/read/26494983/phase-transformation-in-radially-merged-wurtzite-gaas-nanowires
#14
Daniel Jacobsson, Fangfang Yang, Karla Hillerich, Filip Lenrick, Sebastian Lehmann, Dominik Kriegner, Julian Stangl, L Reine Wallenberg, Kimberly A Dick, Jonas Johansson
III-V Nanowires (NWs) grown with metal-organic chemical vapor deposition commonly show a polytypic crystal structure, allowing growth of structures not found in the bulk counterpart. In this paper we studied the radial overgrowth of pure wurtzite (WZ) GaAs nanowires and characterized the samples with high resolution X-ray diffraction (XRD) to reveal the crystal structure of the grown material. In particular, we investigated what happens when adjacent WZ NWs radially merge with each other by analyzing the evolution of XRD peaks for different amounts of radial overgrowth and merging...
October 7, 2015: Crystal Growth & Design
https://www.readbyqxmd.com/read/26492008/iron-sensitizer-converts-light-to-electrons-with-92-yield
#15
Tobias C B Harlang, Yizhu Liu, Olga Gordivska, Lisa A Fredin, Carlito S Ponseca, Ping Huang, Pavel Chábera, Kasper S Kjaer, Helena Mateos, Jens Uhlig, Reiner Lomoth, Reine Wallenberg, Stenbjörn Styring, Petter Persson, Villy Sundström, Kenneth Wärnmark
Solar energy conversion in photovoltaics or photocatalysis involves light harvesting, or sensitization, of a semiconductor or catalyst as a first step. Rare elements are frequently used for this purpose, but they are obviously not ideal for large-scale implementation. Great efforts have been made to replace the widely used ruthenium with more abundant analogues like iron, but without much success due to the very short-lived excited states of the resulting iron complexes. Here, we describe the development of an iron-nitrogen-heterocyclic-carbene sensitizer with an excited-state lifetime that is nearly a thousand-fold longer than that of traditional iron polypyridyl complexes...
November 2015: Nature Chemistry
https://www.readbyqxmd.com/read/26443552/growth-parameter-design-for-homogeneous-material-composition-in-ternary-ga-x-in-1-x-p-nanowires
#16
Alexander Berg, Filip Lenrick, Neimantas Vainorius, Jason P Beech, L Reine Wallenberg, Magnus T Borgström
Ternary nanowires (NWs) often exhibit varying material composition along the NW growth axis because of different diffusion properties of the precursor molecules. This constitutes a problem for optoelectronic devices for which a homogeneous material composition is most often of importance. Especially, ternary GaInP NWs grown under a constant Ga-In precursor ratio typically show inhomogeneous material composition along the length of the NW due to the complexity of low temperature precursor pyrolysis and relative rates of growth species from gas phase diffusion and surface diffusion that contribute to synthesis of particle-assisted growth...
October 30, 2015: Nanotechnology
https://www.readbyqxmd.com/read/26350694/ipsilateral-facial-tactile-hypesthesia-in-a-patient-with-lateral-medullary-syndrome
#17
Masahiro Katsumata, Koichi Oki, Jin Nakahara, Yoshikane Izawa, Takato Abe, Shinichi Takahashi, Norihiro Suzuki
BACKGROUND: Various sensory impairments have been reported in patients with lateral medullary syndrome, also known as Wallenberg syndrome. The typical sensory impairments experienced by patients with this condition are ipsilateral facial and contralateral trunk and limb thermal hypesthesia and hypoalgesia. Tactile (light touch) sensation is not generally diminished. Here we report the case of a 35-year-old man with lateral medullary infarction who had atypical sensory impairment. METHODS: We examined the results from the neurological examination of the patient as well as findings from computed tomography of the head and magnetic resonance imaging...
November 2015: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/26271558/-treatment-of-upper-esophageal-sphincter-achalasia-as-a-little-known-chapter-of-surgery
#18
M M Abakumov, I A Avdiunina
It is presented the results of survey and treatment of 32 patients with upper esophageal sphincter achalasia. In 29 of them achalasia was consequence of stroke in brain stem (Zakharchenko-Wallenberg syndrome). 28 patients were operated using P. Chodoch method in 7 cases and author's technique of myotomy with pharyngoesophageal junction plasty in 21 patients. Plastic myotomy gives excellent and good results in 81% of observations due to preservation of innervation of muscles providing function of epiglottis and pharyngeal constrictors...
2015: Khirurgiia
https://www.readbyqxmd.com/read/26257194/late-onset-recurrent-mania-as-a-manifestation-of-wallenberg-syndrome-a-case-report-and-review-of-the-literature
#19
Piyush Das, Amit Chopra, Abhishek Rai, Preetha Sharone Kuppuswamy
OBJECTIVE: The aim of the present case report was to describe the late onset of recurrent mania in a patient after ischemic injury to the cerebellum and dorsolateral medulla. METHODS: We studied an 86-year-old male with no prior psychiatric history who developed recurrent episodes of mania following a brain stroke. Additionally, he had neurological symptom constellation typical of Wallenberg syndrome. RESULTS: Magnetic resonance imaging of the brain revealed infarction in the inferomedial right cerebellar hemisphere and the right dorsolateral medulla in the right posterior inferior cerebellar artery (PICA) distribution...
September 2015: Bipolar Disorders
https://www.readbyqxmd.com/read/26123876/repeated-transient-wallenberg-s-syndrome-probable-association-with-ipsilateral-vertebral-artery-hypoplasia-and-aortic-valve-disease
#20
Feng-Di Liu, Rong Zhao, Shuo Wang, Wen-Ting Li, Xiao-Xiao Tao, Ting Sun, Xiao-Lei Shen, Jian-Ren Liu
BACKGROUND: Here we report a rare case of repeated transient Wallenberg's syndrome and discuss its mechanism. METHODS: Case report and literature review. RESULTS: A 57-year-old man was admitted for 1.5-month repeated transient Wallenberg's syndrome, including right-sided Horner's syndrome, lower limb weakness, and paresthesia on the right side of the body and face. His symptom appeared mostly during physical activity. Symptoms occurred nearly everyday and lasted from 5 minutes to 30 minutes...
August 2015: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
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