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https://www.readbyqxmd.com/read/28303385/after-effects-of-cerebellar-continuous-theta-burst-stimulation-on-reflexive-saccades-and-smooth-pursuit-in-humans
#1
Silvia Colnaghi, P Colagiorgio, S Ramat, E D'Angelo, G Koch, M Versino
The use of cerebellar repetitive transcranial magnetic stimulation has been attempted for perturbing reflexive and voluntary eye movements, but discrepancies are seen between the results of distinct studies possibly due to the different stimulation sites, intensities, and paradigms. We describe the after effects of 20 and 40 s continuous Theta Burst Stimulation (cTBS) as compared to sham stimulation, applied over the lateral cerebellar vermis and paravermis on Reflexive Saccades (RS) and Smooth Pursuit (SP) eye movements, recorded in the 30 min following stimulation...
March 16, 2017: Cerebellum
https://www.readbyqxmd.com/read/28293537/a-rare-case-of-concomitant-sicca-keratopathy-and-ipsilateral-central-facial-palsy-in-wallenberg-s-dorsolateral-medullary-syndrome
#2
Deborah De Bruyn, Elisabeth Van Aken, Kristien Herman
Objective: To describe a patient with a right-sided supranuclear facial palsy and concomitant sicca keratopathy of the right eye following right-sided dorsolateral medullary infarction. Methods: Our patient underwent a complete ophthalmologic and neurologic examination including biomicroscopy, fundus examination, cranial nerve examination, Shirmer I test, and magnetic resonance imaging of the brain. Results: A 61-year-old woman presented in emergency with a central facial nerve palsy on the right side and truncal ataxia...
2017: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/28264544/efficacy-of-bont-a-and-swallowing-treatment-for-oropharyngeal-dysphagia-recovery-in-a-patient-with-lateral-medullary-syndrome-a-case-study
#3
Irene Battel, Isabella Koch, Federica Biddau, Carla Carollo, Francesco Piccione, Francesca Meneghello, Merico Antonio, Katie Palmer, Rosario Marchese Ragona
BACKGROUND: Wallenberg's syndrome (WS) is known as posterior inferior cerebellar artery syndrome. Dysphagia has been reported from 51% to 94% of the patients, ranging from mild to severe. CASE PRESENTATION: We reported a case of a patient (Male; 52yrs) with WS. MRI showed an intense hypodense area in the dorsolateral part of the ponto-medullary junction. The clinical signs were severe dysphagia, fed by PEG (FOIS 1; PAS 7), sialorrhea, trismus and ataxia. CLINICAL REHABILITATION IMPACT: Dysphagia was treated by botulinum toxin tipe A (BoNT-A), which was injected into the parotid and submandibular salivary glands, temporalis and masseter muscles, cricopharyngeal muscle associated with specific swallowing exercise and food trails...
March 6, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28258876/the-use-of-tissue-plasminogen-activator-in-the-treatment-of-wallenberg-syndrome-caused-by-vertebral-artery-dissection
#4
Alexis Salerno, Bradford V Cotter, Michael E Winters
BACKGROUND: Acute cerebrovascular accident (CVA) is a devastating cause of patient morbidity and mortality. Up to 10% of acute CVAs in young patients are caused by dissection of the vertebral or carotid artery. Wallenberg syndrome results from a CVA in the vertebral or posterior inferior artery of the cerebellum and manifests as various degrees of cerebellar dysfunction. The administration of a thrombolytic medication has been recommended in the treatment of patients with stroke caused by cervical artery dissection...
February 28, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28242416/an-endocrine-basis-for-tomboy-identity-the-second-to-fourth-digit-ratio-2d-4d-in-tomboys
#5
Beth M Atkinson, Tom V Smulders, Joel C Wallenberg
This paper investigates the relationship between organizational effects of pre-natal testosterone and the use of "tomboy" as a descriptor for young women. We show in a sample of 44 women that a woman's right hand 2D:4D ratio is a significant predictor of whether they will be labeled as a "tomboy", with a decrease in 2D:4D ratio corresponding to an increase in the probability of being called "tomboy". Taking the right hand 2D:4D ratio as a proxy for the abundance of testosterone in the early life hormonal milieu, we propose that organizing effects of higher pre-natal T lead to increased masculine-typical behavior in childhood, which increases the likelihood some women will be referred to as tomboys...
February 1, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28239693/metal-passivated-pbs-nanoparticles-fabrication-and-characterization
#6
M Tchaplyguine, M-H Mikkelä, E Mårsell, C Polley, A Mikkelsen, W Zhang, A Yartsev, C J D Hetherington, L R Wallenberg, O Björneholm
Organic-shell-free PbS nanoparticles have been produced in the size range relevant for quantum-dot solar cells (QDSCs) by a vapor aggregation method involving magnetron reactive sputtering. This method creates a beam of free 5-10 nm particles in a vacuum. The dimensions of the particles were estimated after their deposition on a substrate by imaging them using ex situ SEM and HRTEM electron microscopy. The particle structure and chemical composition could be deduced "on the fly", prior to deposition, using X-ray photoelectron spectroscopy (XPS) with tunable synchrotron radiation...
February 27, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28089423/crossed-cheiro-oral-syndrome-a-warning-sign-for-medullary-involvement-and-neurological-deterioration
#7
Wei-Hsi Chen, Tsung-Pei Yang, Hsin-Ling Yin
Crossed cheiro-oral syndrome (CCOS) is characterized by crossed sensory disturbance confined to the unilateral perioral area and contralateral hand/finger(s). Although a few classical crossed sensory syndromes accurately predict brainstem or spinal involvement, the clinical significance of CCOS remains unclear. In this study, we analyzed the etiology, localization and outcome of CCOS patients. The results showed that ischemic stroke is the exclusive cause of CCOS. The location of responsible stroke is pertinent to the middle or upper level of the lateral medulla oblongata medial to the lateral sulcus...
January 12, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27815089/association-between-excessive-bmi-increase-during-puberty-and-risk-of-cardiovascular-mortality-in-adult-men-a-population-based-cohort-study
#8
Claes Ohlsson, Maria Bygdell, Arvid Sondén, Annika Rosengren, Jenny M Kindblom
BACKGROUND: Being overweight during childhood and adolescence is associated with increased risk of cardiovascular disease in adulthood, but the relative contribution of prepubertal childhood BMI and BMI change during puberty to adult mortality due to cardiovascular disease is unknown. We assessed the contribution of these two distinct developmental BMI parameters for cardiovascular mortality in adult men. METHODS: As a part of the ongoing population-based BMI Epidemiology Study (BEST) in Gothenburg, Sweden, men born between 1945 and 1961 with information on both their childhood BMI at age 8 years and BMI change during puberty were included in the study and followed up until December, 2013...
December 2016: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/27732960/selenite-promotes-all-trans-retinoic-acid-induced-maturation-of-acute-promyelocytic-leukemia-cells
#9
Sougat Misra, Arun Kumar Selvam, Marita Wallenberg, Aditya Ambati, András Matolcsy, Isabelle Magalhaes, Gilbert Lauter, Mikael Björnstedt
Selective targeting of the PML/RARα oncoprotein demonstrates a successful molecular targeted therapy in acute promyelocytic leukemia (APL) with a typical t(15:17) chromosomal translocation. The zinc-thiolate coordination is critical for structural stability of zinc finger proteins, including the PML moiety of PML/RARα. Based on the known interaction of redox-active selenium compounds with thiolate ligands of zinc, we herein have investigated the abrogatory effects of selenite alone or in combination with all-trans retinoic acid on PML/RARα and the possible effects on differentiation in these cells...
November 15, 2016: Oncotarget
https://www.readbyqxmd.com/read/27564139/gaasp-nanowires-grown-by-aerotaxy
#10
Wondwosen Metaferia, Axel R Persson, Kilian Mergenthaler, Fangfang Yang, Wei Zhang, Arkady Yartsev, Reine Wallenberg, Mats-Erik Pistol, Knut Deppert, Lars Samuelson, Martin H Magnusson
We have grown GaAsP nanowires with high optical and structural quality by Aerotaxy, a new continuous gas phase mass production process to grow III-V semiconductor based nanowires. By varying the PH3/AsH3 ratio and growth temperature, size selected GaAs1-xPx nanowires (80 nm diameter) with pure zinc-blende structure and with direct band gap energies ranging from 1.42 to 1.90 eV (at 300 K), (i.e., 0 ≤ x ≤ 0.43) were grown, which is the energy range needed for creating tandem III-V solar cells on silicon. The phosphorus content in the NWs is shown to be controlled by both growth temperature and input gas phase ratio...
September 14, 2016: Nano Letters
https://www.readbyqxmd.com/read/27450474/effects-of-alteplase-on-survival-after-ischaemic-stroke-ist-3-3-year-follow-up-of-a-randomised-controlled-open-label-trial
#11
Eivind Berge, Geoffrey Cohen, Melinda B Roaldsen, Erik Lundström, Eva Isaksson, Ann-Sofie Rudberg, Karsten Bruins Slot, John Forbes, Joel Smith, Jonathan Drever, Joanna M Wardlaw, Richard I Lindley, Peter A G Sandercock, William N Whiteley
BACKGROUND: The effect of alteplase on patient survival after ischaemic stroke is the subject of debate. We report the effect of intravenous alteplase on long-term survival after ischaemic stroke of participants in the Third International Stroke Trial (IST-3). METHODS: In IST-3, done at 156 hospitals in 12 countries (Australia, Europe, and the UK), participants (aged >18 years) were randomly assigned with a telephone voice-activated or web-based system in a 1:1 ratio to treatment with intravenous 0·9 mg/kg alteplase plus standard care or standard care alone within 6 h of ischaemic stroke...
September 2016: Lancet Neurology
https://www.readbyqxmd.com/read/27356655/endovascular-treatment-of-distal-posterior-inferior-cerebellar-artery-aneurysms
#12
Jun Tang, Linjie Wei, Lin Li, Yin Niu, Qianwei Chen, Hua Feng, Gang Zhu, Zhi Chen
OBJECTIVE: To assess the feasibility and results of endovascular treatment for ruptured distal posterior inferior cerebellar artery (PICA) aneurysms. METHODS: We retrospectively reviewed our experience and results with endovascular treatments for a series of 13 consecutive patients with ruptured distal PICA aneurysms at the Southwest Hospital, Chongqing, China, treated between June 2011 and January 2015. Therapeutic considerations, intraoperative complications, and results were evaluated...
July 2016: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/27246963/wallenberg-s-lateral-medullary-syndrome-in-an-adolescent
#13
Elizabeth Day Ruedrich, Mahesh Chikkannaiah, Gogi Kumar
No abstract text is available yet for this article.
November 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27206871/ipsilateral-hemiparesis-in-lateral-medullary-infarction-clinical-investigation-of-the-lesion-location-on-magnetic-resonance-imaging
#14
Masahiro Uemura, Hiroaki Naritomi, Hisakazu Uno, Arisa Umesaki, Kotaro Miyashita, Kazunori Toyoda, Kazuo Minematsu, Kazuyuki Nagatsuka
BACKGROUND: In 1946, Opalski reported two cases of Wallenberg syndrome with ipsilateral hemiparesis (IH). His hypothesis seems to be based on the view that IH is caused by post-decussating pyramidal tract damage. Afterwards, other researchers proposed a different hypothesis that ipsilateral sensory symptoms of limbs (ISSL) or ipsilateral limb ataxia (ILA) caused by lateral medullary infarction (LMI) might lead to ipsilateral motor weakness. The present study is aimed to clarify whether IH in LMI patients is attributable mainly to ISSL/ILA or disruption of ipsilateral post-decussating pyramidal tract...
June 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27068280/csf-and-blood-biomarkers-for-the-diagnosis-of-alzheimer-s-disease-a-systematic-review-and-meta-analysis
#15
Bob Olsson, Ronald Lautner, Ulf Andreasson, Annika Öhrfelt, Erik Portelius, Maria Bjerke, Mikko Hölttä, Christoffer Rosén, Caroline Olsson, Gabrielle Strobel, Elizabeth Wu, Kelly Dakin, Max Petzold, Kaj Blennow, Henrik Zetterberg
BACKGROUND: Alzheimer's disease biomarkers are important for early diagnosis in routine clinical practice and research. Three core CSF biomarkers for the diagnosis of Alzheimer's disease (Aβ42, T-tau, and P-tau) have been assessed in numerous studies, and several other Alzheimer's disease markers are emerging in the literature. However, there have been no comprehensive meta-analyses of their diagnostic performance. We systematically reviewed the literature for 15 biomarkers in both CSF and blood to assess which of these were most altered in Alzheimer's disease...
June 2016: Lancet Neurology
https://www.readbyqxmd.com/read/26989533/babinski-nageotte-syndrome-diagnosed-in-postpartum-period
#16
Serdar Oruç, Hayri Demirbaş, Abdullah Güzel, Mehtap Beker Acay, Mehmet Yaman
Babinski-Nageotte Syndrome (BNS) is one of the brainstem syndromes characterized by muscle weakness in the opposite half of the body with classic Wallenberg findings. According to our literature survey, only a few cases have been reported and none of them was in the postpartum period. We report a case of a typical BNS in a postpartum woman with an ischemic lesion in the medulla oblongata shown on magnetic resonance imaging.
2016: Case Reports in Neurological Medicine
https://www.readbyqxmd.com/read/26960272/-multiple-cerebral-artery-occlusion-due-to-non-bacterial-thrombotic-endocarditis-an-autopsy-case-report
#17
Yoshinari Nagakane, Hidesato Takezawa, Kanade Katsura, Yasumasa Yamamoto
A 60-year-old man was admitted to our hospital because of vertigo and repeated vomiting, which suddenly occurred 25 hours before admission. Neurologic examination revealed Wallenberg syndrome on the left side, and brain MRI showed acute infarcts in the left lateral medulla as well as in the left internal carotid artery (ICA) territory. MR angiography did not depict the left vertebral artery (VA) and the left ICA. Despite antithrombotic treatment, he developed bulbar palsy, and then, brain herniation due to infarct growth in the left middle cerebral artery territory...
2016: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/26838122/electron-microscopy-imaging-of-proteins-on-gallium-phosphide-semiconductor-nanowires
#18
Martin Hjort, Mikael Bauer, Stefan Gunnarsson, Erik Mårsell, Alexei A Zakharov, Gunnel Karlsson, Elodie Sanfins, Christelle N Prinz, Reine Wallenberg, Tommy Cedervall, Anders Mikkelsen
We have imaged GaP nanowires (NWs) incubated with human laminin, serum albumin (HSA), and blood plasma using both cryo-transmission electron microscopy and synchrotron based X-ray photoemission electron microscopy. This extensive imaging methodology simultaneously reveals structural, chemical and morphological details of individual nanowires and the adsorbed proteins. We found that the proteins bind to NWs, forming coronas with thicknesses close to the proteins' hydrodynamic diameters. We could directly image how laminin is extending from the NWs, maximizing the number of proteins bound to the NWs...
February 21, 2016: Nanoscale
https://www.readbyqxmd.com/read/26810508/two-young-stroke-patients-associated-with-regular-intravenous-immunoglobulin-ivig-therapy
#19
Yumiko Nakano, Takeshi Hayashi, Kentaro Deguchi, Kota Sato, Nozomi Hishikawa, Toru Yamashita, Yasuyuki Ohta, Yoshiki Takao, Tomohiro Morio, Koji Abe
We recently experienced 2 young adult patients who developed ischemic stroke after regular intravenous immunoglobulin (IVIg) therapy for agammaglobulinemia with diagnosis of common variable immunodeficiency (CVID) in their childhood. Patient 1 was 26-year-old woman, who developed Wallenberg's syndrome 6 days after the last IVIg therapy, but had no further stroke recurrence with cilostazol later. Patient 2 was 37-year-old man, who developed recurrent cerebral infarction in the territory of bilateral lenticulostriate branches like branch atheromatous disease (BAD) several days after the IVIg therapy...
February 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/26569158/wallenberg-syndrome-an-exceptional-cause-of-acute-vertigo-in-children
#20
Aude Ménétrey Ehresmann, Hélène Cao Van, Laura Merlini, Joel Fluss
The assessment of acute vertigo in childhood is often challenging, but fortunately a central cause is rarely identified. We present the case of a 7-year-old boy who developed, after a mild head trauma, a rotary vertigo associated with nausea and vomiting. A posttraumatic peripheral vestibular dysfunction was first suspected but not confirmed by an otoneurological evaluation. When subtle neurological signs were elicited, a brain magnetic resonance imaging was promptly requested. This showed a small infarct on the lateral posterior left part of the medulla oblongata of the brainstem, typical of Wallenberg syndrome...
January 2016: Neuropediatrics
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