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https://www.readbyqxmd.com/read/29331884/true-left-sided-gallbladder-a-case-report-and-comparison-with-the-literature-for-the-different-techniques-of-laparoscopic-cholecystectomy-for-such-anomalies
#1
Tamer Saafan, James Yi Hu, Ahmed-Emad Mahfouz, Abdelrahman Abdelaal
INTRODUCTION: True left-sided gallbladder (LSG) is a rare finding that may present with symptoms similar to those of a normally positioned gallbladder. Moreover, it may be missed by preoperative imaging studies such as ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), or endoscopic ultrasound. True left-sided gallbladder is a surgical challenge and surgical technique may need to be modified for the completion of laparoscopic cholecystectomy. PRESENTATION OF CASE: In this case report, we present a case of true left-sided gallbladder that produced right-sided abdominal symptoms...
December 27, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29330717/posterior-retroperitoneoscopic-resection-of-extra-adrenal-paraganglioma-located-in-the-aorto-caval-space
#2
Sang-Wook Kang, Emad Kandil, Min Jhi Kim, Kwang Soon Kim, Cho Rok Lee, Jong Ju Jeong, Kee-Hyun Nam, Woong Youn Chung, Cheong Soo Park
BACKGROUND: The posterior retroperitoneoscopic adrenalec tomy has several advantages compared with the transperitoneal approach such as a shorter and more direct route to the target organ, no breach of the intraperitoneal space, and no required retraction of the adjacent organs. It also is a safe procedure with a short learning curve.1-5 This report presents a challenging case of an extra-adrenal paraganglioma located in the aorto-caval space and managed using the retroperitoneal approach...
January 12, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29327245/high-nuclear-msk1-is-associated-with-longer-survival-in-breast-cancer-patients
#3
Xuan Pu, Sarah J Storr, Narmeen S Ahmad, Emad A Rakha, Andrew R Green, Ian O Ellis, Stewart G Martin
PURPOSE: Mitogen- and stress-activated kinases (MSKs) are important substrates of the mitogen-activated protein kinase (MAPK)-activated protein kinase family. MSK1 and MSK2 are both nuclear serine/threonine protein kinases, with MSK1 being suggested to potentially play a role in breast cancer cell proliferation, cell cycle progression, cell migration, invasion and tumour growth. The aim of the current study was to assess MSK1 protein expression in breast cancer tumour specimens, evaluating its prognostic significance...
January 11, 2018: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/29326189/period-prevalence-risk-factors-and-consequent-injuries-of-falling-among-the-saudi-elderly-living-in-riyadh-saudi-arabia-a-cross-sectional-study
#4
Faisal Yousef Almegbel, Ibrahim Muthyib Alotaibi, Faisal Ahmed Alhusain, Emad M Masuadi, Salma Lafyan Al Sulami, Amairah Fahad Aloushan, Bashayer Ibrahim Almuqbil
OBJECTIVES: Approximately 28% to 35% of people aged 65 and over fall each year. The consequent injuries of falls are considered a major public health problem. Falls account for more than half of injury-related hospitalisations among old people. The aim of this study was to measure a 1-year period prevalence of falling among old people in Riyadh, Saudi Arabia. In addition, this study described the most common risk factors and consequent injuries of falls. SETTING AND PARTICIPANTS: A cross-sectional survey was carried out in Riyadh, using a convenient sampling...
January 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29321845/failure-to-define-low-back-pain-as-a-disease-or-an-episode-renders-research-on-causality-unsuitable-results-of-a-systematic-review
#5
REVIEW
Emad M Ardakani, Charlotte Leboeuf-Yde, Bruce F Walker
Background: Causative factors may be different for the very first onset of symptoms of the 'disease' of low back pain (LBP) than for ensuing episodes that occur after a pain-free period. This differentiation hinges on a life-time absence of low back pain at first onset and short-term absence for further episodes. In this systematic review, we explored whether researchers make these distinctions when investigating the causality of LBP. Methods: A literature search of PUBMED, CINAHL, and SCOPUS databases was performed from January 2010 until September 2016 using the search terms 'low back pain' or 'back pain' and 'risk factor' or 'caus*' or 'predict*' or 'onset' or 'first-time' or 'inception' or 'incidence'...
2018: Chiropractic & Manual Therapies
https://www.readbyqxmd.com/read/29321798/impact-of-triple-antithrombotic-therapy-in-patients-with-acute-coronary-syndrome-undergoing-percutaneous-coronary-intervention-in-real-world-practice
#6
Yan Yan, Xiao Wang, Jing-Yao Fan, Shao-Ping Nie, Sergio Raposeiras-Roubín, Emad Abu-Assi, Jose P Simao Henriques, Fabrizio D'Ascenzo, Jorge Saucedo, José R González-Juanatey, Stephen B Wilton, Wouter J Kikkert, Iván Nuñez-Gil, Albert Ariza-Sole, Xian-Tao Song, Dimitrios Alexopoulos, Christoph Liebetrau, Tetsuma Kawaji, Claudio Moretti, Zenon Huczek, Toshiharu Fujii, Luis Cl Correia, Masa-Aki Kawashiri, Sasko Kedev
Objective: The optimal antithrombotic regimen for patients on oral anticoagulation (OAC) after acute coronary syndrome (ACS) and percutaneous coronary intervention (PCI) remains debated. This study sought to evaluate the efficacy and safety of OAC plus clopidogrel with or without aspirin in a real-world setting. Methods: We retrospectively analyzed data from an international, multi-center registry between 2003 and 2014 (n = 15,401). Patients with ACS and receiving OAC after PCI were screened...
November 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/29321468/length-of-stay-and-functional-outcomes-among-patients-with-stroke-discharged-from-an-inpatient-rehabilitation-facility-in-saudi-arabia
#7
Saad M Bindawas, Vishal Vennu, Hussam Mawajdeh, Hisham M Alhaidary, Emad Moftah
BACKGROUND In many countries, the length of stay (LOS) for inpatient rehabilitation following stroke has gradually decreased. It is unclear whether this trend is associated with differences in functional outcomes, especially in developing countries. This study aimed to examine associations between LOS and functional outcomes among patients with stroke discharged from an inpatient rehabilitation facility in Saudi Arabia. MATERIAL AND METHODS This retrospective study included all patients (N=409) aged ≥18 years who were admitted to an inpatient rehabilitation for stroke during 2008-2014...
January 11, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29316435/molecular-predictors-of-gastric-neoplastic-progression
#8
Paul Lochhead, Emad M El-Omar
In this issue of Cancer Cell, Huang et al. describe comprehensive genetic and epigenetic profiling of gastric intestinal metaplasia lesions from a longitudinal cohort in which outcome data allowed for identification of potential markers of gastric neoplastic progression.
January 8, 2018: Cancer Cell
https://www.readbyqxmd.com/read/29306773/midlife-stress-alters-memory-and-mood-related-behaviors-in-old-age-role-of-locally-activated-glucocorticoids
#9
Nicola Wheelan, Christopher J Kenyon, Anjanette P Harris, Carolynn Cairns, Emad Al Dujaili, Jonathan R Seckl, Joyce L W Yau
Chronic exposure to stress during midlife associates with subsequent age-related cognitive decline and may increase the vulnerability to develop psychiatric conditions. Increased hypothalamic-pituitary-adrenal (HPA) axis activity has been implicated in pathogenesis though any causative role for glucocorticoids is unestablished. This study investigated the contribution of local glucocorticoid regeneration by the intracellular enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), in persisting midlife stress-induced behavioral effects in mice...
December 23, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29306693/the-iraqi-national-study-of-suicide-report-on-suicide-data-in-iraq-in-2015-and-2016
#10
Mohammed J Abbas, Nesif Alhemiary, Emad Abdul Razaq, Shakir Naosh, Louis Appleby
BACKGROUND: Very little is known regarding the epidemiology of suicides in Iraq, given the lack of a national surveillance system. Therefore, the government initiated this project "The Iraqi National Study of Suicide METHODS: The study covered 13 (out of 18) provinces in Iraq. A data collection form was designed by the researchers. The forms were completed by police stations in the 13 provinces. Data were extracted from the legal investigation (which include police investigation, family reports and postmortem reports) of cases of when there was no clear cause of death and where there was final verdict of suicide made by judge after examining these reports...
December 27, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29303777/evaluation-of-serum-beta-endorphin-and-substance-p-in-knee-osteoarthritis-patients-treated-by-laser-acupuncture
#11
Nagwa Mohammed, Hemat Allam, Eman Elghoroury, Emad N Zikri, Ghada A Helmy, Aliaa Elgendy
Background Laser acupuncture is one of the complementary modalities used for treating osteoarthritis. The study was performed to evaluate the effectiveness of laser acupuncture in the treatment of grade 2 knee osteoarthritis. Patients and methods Forty patients having bilateral knee osteoarthritis were divided into two groups (20 patients in each group). The patients of the first group were subjected to 12 laser sessions at the following acupoints (St 35, St36, Sp9, Sp10 and Gb 34). During each session, laser of 90 mw was directed to each acupoint for 1 min giving energy of 5...
January 5, 2018: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/29302493/locally-advanced-asymptomatic-papillary-thyroid-cancer-presenting-with-retropharyngeal-lymph-node-metastasis-symptoms
#12
Roostam Kholmatov, Obinwanne Emejulu, Fadi Murad, Rizwan Aslam, Emad Kandil
Papillary thyroid cancer (PTC) rarely metastasizes to the retropharyngeal lymph nodes. Managing patients with locally advanced primary PTC and metastasis located in distant anatomical areas is challenging. Herein, we report a 56-year-old patient with locally advanced asymptomatic PTC, who presented with obstructive airway symptoms due to the metastatic retropharyngeal lymph node. The patient underwent simultaneous total thyroidectomy, central lymph node dissection, en bloc resection of strap muscle and left laryngeal nerve via cervical approach and transoral resection of the metastatic retropharyngeal lymph node...
December 2017: Gland Surgery
https://www.readbyqxmd.com/read/29302491/an-ectopic-intrathyroidal-thymic-tissue-and-intrathymic-parathyroid-tissue-in-a-patient-with-graves-disease
#13
Kelly O'Connor, Hassan Alzahrani, Fadi Murad, Philip Daroca, Emad Kandil
Ectopic intrathyroidal thymic tissue, with coinciding intrathymic parathyroid tissue, is a very rare occurrence that is most often found incidentally in adults during surgery. We report a 23-year-old female who presented with Graves disease refractory to medical treatment. Radioactive iodine uptake demonstrated increased, diffuse uptake in the region of the thyroid. The patient underwent a total thyroidectomy and right inferior parathyroidectomy which was found enlarged intraoperatively. Histopathologically, surgical specimen demonstrated characteristics of intrathyroidal thymic tissue and intrathymic parathyroid tissue...
December 2017: Gland Surgery
https://www.readbyqxmd.com/read/29302476/robotic-and-endoscopic-transoral-thyroidectomy-feasibility-and-description-of-the-technique-in-the-cadaveric-model
#14
Bora Kahramangil, Khuzema Mohsin, Hassan Alzahrani, Daniah Bu Ali, Syed Tausif, Sang-Wook Kang, Emad Kandil, Eren Berber
Background: Numerous new approaches have been described over the years to improve the cosmetic outcomes of thyroid surgery. Transoral approach is a new technique that aims to achieve superior cosmetic outcomes by concealing the incision in the oral cavity. Methods: Transoral thyroidectomy through vestibular approach was performed in two institutions on cadaveric models. Procedure was performed endoscopically in one institution, while the robotic technique was utilized at the other...
December 2017: Gland Surgery
https://www.readbyqxmd.com/read/29299856/malononitrile-dimer-as-a-privileged-reactant-in-design-and-skeletal-diverse-synthesis-of-heterocyclic-motifs
#15
REVIEW
Ahmad Shaabani, Seyyed Emad Hooshmand
Malononitrile dimer as a precursor reactant has been extensively applied in the diversity-oriented synthesis of various heterocyclic motifs, bis-heterocyclic compounds, fused heterocycle derivatives, bicyclic bridged heterocyclic scaffolds, and highly substituted carbocyclic compounds. These remarkable products were synthesized via various types of reactions, such as cycloaddition, cyclocondensation, cascade/domino/tandem reactions along with multi-component reactions. In addition, the flexibility and high reactivity of malononitrile dimer as a multi-functional reagent and its potential to the preparation of novel beneficial scaffolds as well as biologically active molecules signify it as a suitable building block in total synthesis, medicinal chemistry, and dyes...
January 3, 2018: Molecular Diversity
https://www.readbyqxmd.com/read/29299515/models-for-the-study-of-nasal-and-sinus-physiology-in-health-and-disease-a-review-of-the-literature
#16
REVIEW
Ahmed A Al-Sayed, Remigius U Agu, Emad Massoud
Objective: Chronic sinusitis is a very common yet poorly understood medical condition with significant morbidity. Hence, it remains an entity that is difficult to treat with unsatisfactory outcomes of current management options. This necessitates research into the etiology and pathophysiology of the condition to enhance our knowledge and the therapeutic options. Unfortunately, this kind of research is not always feasible on human subjects due to practical and ethical limitations. Therefore, an alternative model that simulates the disease had to be found in order to overcome these limitations...
December 2017: Laryngoscope Investigative Otolaryngology
https://www.readbyqxmd.com/read/29288380/knowledge-and-attitude-towards-total-knee-arthroplasty-among-the-public-in-saudi-arabia-a-nationwide-population-based-study
#17
Omar A Al-Mohrej, Faris O Alshammari, Abdulrahman M Aljuraisi, Lujain A Bin Amer, Emad M Masuadi, Nader S Al-Kenani
PURPOSE: Studies on total knee arthroplasty (TKA) in Saudi Arabia are scarce, and none have reported the knowledge and attitude of the procedure in Saudi Arabia. Our study aims to measure the knowledge and attitude of TKA among the adult Saudi population. METHODS: To encompass a representative sample of this cross-sectional survey, all 13 administrative areas were used as ready-made geographical clusters. For each cluster, stratified random sampling was performed to maximize participation in the study...
December 29, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/29258367/evaluation-of-prolonged-use-of-statins-on-the-clinical-and-biochemical-abnormalities-and-ovulation-dysfunction-in-single-young-women-with-polycystic-ovary-syndrome
#18
Emaduldin Seyam, Saad Al Gelany, Ahmed Abd Al Ghaney, Marwa Abd Allah Mohamed, Ayman Moheb Youseff, Emad Moussa Ibrahim, Eissa M Khalifa, Enas Hefzy
OBJECTIVE: The aim of the current work was to investigate the effects of prolonged use of Statins on the clinical and biochemical abnormalities and ovulation dysfunction in young single women with polycystic ovary syndrome (PCOS). PATIENTS AND METHODS: It was a randomized, double-blind, placebo-controlled study. Where 200 single young women with PCOS were randomized into either 100 (n = 100) women using Simvastatin 20 mg daily considered as group A (study group), or 100 (n = 100) women using placebo and considered as group B (control group), for six months treatment period...
December 19, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29243836/the-long-term-prognostic-value-of-highly-sensitive-cardiac-troponin-i-in-patients-with-acute-pulmonary-embolism
#19
Katherine Lee Chuy, Emad Uddin Hakemi, Tareq Alyousef, Geetanjali Dang, Rami Doukky
BACKGROUND: In patients with acute pulmonary embolism (PE), detectable levels of cardiac troponin I (cTnI) using a highly sensitive assay have been associated with increased in-hospital mortality. We sought to investigate the impact of detectable cTnI on long-term survival following acute PE. HYPOTHESIS: Detectable cTnI levels in patients presenting with acute PE predict increased long-term mortality following hospital discharge. METHODS: In a retrospective cohort study, we analyzed consecutive patients with confirmed acute PE and cTnI assay available from the index hospitalization...
December 15, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/29242974/effect-of-intramural-fibroid-on-uterine-and-endometrial-vascularity-in-infertile-women-scheduled-for-in-vitro-fertilization
#20
Ahmed Kamel, Akmal El-Mazny, Wafaa Ramadan, Suzy Abdelaziz, Sherine Gad-Allah, Hany Saad, Ahmed M Hussein, Emad Salah
PURPOSE: To study the effect of intramural fibroids on uterine and endometrial vascularity in infertile women scheduled for in-vitro fertilization (IVF). METHODS: 3D power Doppler was used to measure the endometrial volume and blood flow indices in 182 women with intramural fibroids not affecting the uterine cavity and compared them to a matched control group without fibroids. RESULTS: There was significantly increased vascularity in the endometrium of the fibroid group as denoted by higher endometrial VI (p = 0...
December 14, 2017: Archives of Gynecology and Obstetrics
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