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EPIC Valve

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https://www.readbyqxmd.com/read/28962508/replica-sizing-strategy-for-aortic-valve-replacement-improves-haemodynamic-outcome-of-the-epic-supra-valve
#1
David Gonzalez-Lopez, Gloria Faerber, Mahmoud Diab, Paulo Amorim, Natig Zeynalov, Torsten Doenst
OBJECTIVES: Current sizing strategies suggest valve selection based on annulus diameter despite supra-annular placement of biological prostheses potentially allowing placement of a larger size. We assessed the frequency of selecting a larger prosthesis if prosthesis size was selected using a replica (upsizing) and evaluated its impact on haemodynamics. METHODS: We analysed all discharge echocardiograms between June 2012 and June 2014, where a replica sizer was used for isolated aortic valve replacement (Epic Supra: 266 patients, Trifecta: 49 patients)...
October 1, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28698291/bioprosthetic-valve-fracture-improves-the-hemodynamic-results-of-valve-in-valve-transcatheter-aortic-valve-replacement
#2
Adnan K Chhatriwalla, Keith B Allen, John T Saxon, David J Cohen, Sanjeev Aggarwal, Anthony J Hart, Suzanne J Baron, Danny Dvir, A Michael Borkon
BACKGROUND: Valve-in-valve (VIV) transcatheter aortic valve replacement (TAVR) may be less effective in small surgical valves because of patient/prosthesis mismatch. Bioprosthetic valve fracture (BVF) using a high-pressure balloon can be performed to facilitate VIV TAVR. METHODS AND RESULTS: We report data from 20 consecutive clinical cases in which BVF was successfully performed before or after VIV TAVR by inflation of a high-pressure balloon positioned across the valve ring during rapid ventricular pacing...
July 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28669505/bioprosthetic-valve-fracture-to-facilitate-transcatheter-valve-in-valve-implantation
#3
Keith B Allen, Adnan K Chhatriwalla, David J Cohen, John T Saxon, Sanjeev Aggarwal, Anthony Hart, Suzanne Baron, J Russell Davis, Alex F Pak, Danny Dvir, A Michael Borkon
BACKGROUND: Valve-in-valve transcatheter aortic valve replacement is less effective in small surgical bioprostheses. We evaluated the feasibility of bioprosthetic valve fracture with a high-pressure balloon to facilitate valve-in-valve transcatheter aortic valve replacement. METHODS: In vitro bench testing on aortic tissue valves was performed on 19-mm and 21-mm Mitroflow (Sorin, Milan, Italy), Magna and Magna Ease (Edwards Lifesciences, Irvine, CA), Trifecta and Biocor Epic (St...
November 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28461800/bioprosthetic-aortic-valve-replacement-in-a-donor-heart-before-orthotopic-heart-transplantation
#4
Manish Patel, Khashayar K Vahdat, Sriram Nathan, Marija Petrovic, Pranav Loyalka, Biswajit Kar, Igor D Gregoric
Current criteria for donor hearts limit the number of hearts available for transplantation, despite an increasing number of recipients on waiting lists. We report the case of a patient with ischemic cardiomyopathy and refractory ventricular tachycardia who underwent successful orthotopic heart transplantation and concurrent aortic valve replacement with a donor heart that had displayed moderate aortic valve regurgitation. The patient was a 71-year-old man with a history of advanced heart failure, 5-vessel coronary artery bypass grafting, and paroxysmal ventricular tachycardia...
April 2017: Texas Heart Institute Journal
https://www.readbyqxmd.com/read/28228313/significant-intra-valvular-pressure-loss-across-epic-supra-and-perimount-magna-supra-annular-designed-aortic-bioprostheses-in-patients-with-normal-aortic-size
#5
Jagdish C Mohan, Vishwas Mohan, Madhu Shukla, Arvind Sethi
Doppler-derived trans-prosthetic gradients are higher and the estimated effective valve area is smaller than the catheter-derived and directly measured hemodynamic values, mostly due to pressure recovery phenomenon. Pressure recovery to a varying extent is common to all prosthetic heart valves including bioprostheses. Pressure recovery-related differences are usually small except in patients with bileaflet metallic prosthesis, wherein high-pressure local jets across central orifice have been documented since long back and also in patients with narrow aortic root...
January 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28131425/evaluation-of-hemodynamic-performance-of%C3%A2-aortic-valve-bioprostheses-in-a-model-of%C3%A2-oversizing
#6
John D Cleveland, Michael E Bowdish, Carol E Eberhardt, Wendy J Mack, James A Crabtree, Thomas A Vassiliades, Alan M Speir, Yogesh A Darekar, Amy E Hackmann, Vaughn A Starnes, Robbin G Cohen
BACKGROUND: The risk of patient-prosthesis mismatch drives most surgeons to select the largest bioprosthesis possible during aortic valve replacement, but interactions between the native aortic annulus and valve prosthesis remain poorly defined. We examined the hemodynamic and functional consequences of oversizing contemporary bioprostheses in an in vitro model. METHODS: Three sizes each (21, 23, and 25 mm) of 5 aortic bioprostheses (Magna, Edwards Lifesciences, Irvine, CA; Trifecta and Epic, St...
June 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27678080/effect-of-pimobendan-in-dogs-with-preclinical-myxomatous-mitral-valve-disease-and-cardiomegaly-the-epic-study-a-randomized-clinical-trial
#7
A Boswood, J Häggström, S G Gordon, G Wess, R L Stepien, M A Oyama, B W Keene, J Bonagura, K A MacDonald, M Patteson, S Smith, P R Fox, K Sanderson, R Woolley, V Szatmári, P Menaut, W M Church, M L O'Sullivan, J-P Jaudon, J-G Kresken, J Rush, K A Barrett, S L Rosenthal, A B Saunders, I Ljungvall, M Deinert, E Bomassi, A H Estrada, M J Fernandez Del Palacio, N S Moise, J A Abbott, Y Fujii, A Spier, M W Luethy, R A Santilli, M Uechi, A Tidholm, P Watson
BACKGROUND: Pimobendan is effective in treatment of dogs with congestive heart failure (CHF) secondary to myxomatous mitral valve disease (MMVD). Its effect on dogs before the onset of CHF is unknown. HYPOTHESIS/OBJECTIVES: Administration of pimobendan (0.4-0.6 mg/kg/d in divided doses) to dogs with increased heart size secondary to preclinical MMVD, not receiving other cardiovascular medications, will delay the onset of signs of CHF, cardiac-related death, or euthanasia...
November 2016: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/27528537/transhepatic-implant-of-a-trimmed-melody%C3%A2-valved-stent-in-tricuspid-position-in-a-1-year-old-infant
#8
Bjorn Cools, Filip Rega, Marc Gewillig
Percutaneous valved stent implantation is precluded in small infants because large delivery sheaths and large devices. We describe a procedure in a 1-year-old boy in whom a 19 mm Epic™ valve in tricuspid position had become dysfunctional. As the internal diameter of the prosthetic valve was about 16 mm, the only available valve was the Melody™ valved stent. Technical modifications were required to address issues like venous access, the bulky delivery system, and the length of the valved stent. The Melody™ valved stent was surgically trimmed and mounted on a 16 mm Tyshak balloon, access was provided transhepatically through a short 18 Fr sheath...
February 15, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27258099/a-d-shaped-bileaflet-bioprosthesis-which-replicates-physiological-left-ventricular-flow-patterns
#9
Sean Guo-Dong Tan, Sangho Kim, Jimmy Kim Fatt Hon, Hwa Liang Leo
Prior studies have shown that in a healthy heart, there exist a large asymmetric vortex structure that aids in establishing a steady flow field in the left ventricle. However, the implantation of existing artificial heart valves at the mitral position is found to have a negative effect on this physiological flow pattern. In light of this, a novel D-shaped bileaflet porcine bioprosthesis (GD valve) has been designed based on the native geometry mitral valve, with the hypothesis that biomimicry in valve design can restore physiological left ventricle flow patterns after valve implantation...
2016: PloS One
https://www.readbyqxmd.com/read/27062280/apparent-failure-of-automated-threshold-evaluation-what-is-the-mechanism
#10
Vikas Kalra, Lynne Foreman, Deepak Bhakta
No abstract text is available yet for this article.
August 2016: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/26555907/-early-postoperative-outcomes-and-evaluation-of-hemodynamics-after-mitral-valve-replacement-with-epic-mitral-bioprosthesis
#11
Keisuke Kanda, Teruki Kotegawa, Satoshi Kawatsu, Goro Takahashi, Ichiro Yoshioka, Hidenori Fujiwara, Osamu Adachi, Masatoshi Akiyama, Kiichiro Kumagai, Shunsuke Kawamoto, Yoshikatsu Saiki
BACKGROUND: In Guideline for Surgical and Interventional Treatment of Valvular Heart Disease, revised by Japanese Circulation Society in 2012, mitral valve replacement (MVR) with bioprosthesis is class II b recommendation for patients aged 70 years or older who have no risk factors for thromboembolism. The aim of this study was to evaluate the early postoperative surgical outcomes and the hemodynamic performance with the Epic mitral bioprosthesis. METHODS: Twenty-six consecutive patients underwent MVR with Epic mitral bioprostesis at Tohoku University Hospital between April 2011 and July 2014...
November 2015: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/26329714/-pannus-formation-two-years-after-bioprosthetic-aortic-valve-implantation-report-of-a-case
#12
Kimiyo Ono, Hiroaki Kuroda
We report a case of early deterioration of the bioprosthetic aortic valve 23 months postoperatively. A 77-year-old man who had undergone aortic valve replacement with a 23-mm Epic valve( St. Jude Medical [SJM])presented to us after a syncopal episode. Echocardiography revealed severe aortic stenosis, and redo aortic valve replacement with a 21-mm SJM mechanical valve was performed. All 3 cusps of the tissue valve were thickened by fibrous pannus overgrowth. Neither calcification nor invasion of inflammatory cells was observed...
August 2015: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/26066877/-mitral-valve-replacement-with-a-low-profile-bioprosthesis-in-combination-with-septal-myectomy-for-hypertrophic-obstructive-cardiomyopathy-report-of-a-case
#13
Koji Furukawa, Shuhei Sakaguchi, Eisaku Nakamura, Mitsuhiro Yano
An 83-year-old woman diagnosed with hypertrophic obstructive cardiomyopathy was referred to our hospital. Her echocardiogram revealed diffuse left ventricular hypertrophy, severe mitral valve regurgitation with systolic anterior motion of the mitral valve, and left ventricular obstruction with a peak outflow gradient of 142 mmHg. Cardiac catheterization revealed a peak pressure gradient of 60 mmHg across the left ventricular outflow tract. Because of the patient's advanced age, as well as uncertainty regarding our ability to resolve her mitral regurgitation, we performed mitral valve replacement with a St...
June 2015: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/25439772/do-differences-in-early-hemodynamic-performance-of-current-generation-biologic-aortic-valves-predict-outcomes-1-year-following-surgery
#14
RANDOMIZED CONTROLLED TRIAL
Nassir M Thalji, Rakesh M Suri, Hector I Michelena, Kevin L Greason, Joseph A Dearani, Richard C Daly, Lyle D Joyce, John M Stulak, Harold M Burkhart, Zhuo Li, Hartzell V Schaff
OBJECTIVE: Small early postoperative hemodynamic differences were noted in a randomized comparison of 3 current-generation bioprosthetic aortic valves. Whether these differences persist and influence clinical outcomes 1 year following implantation is unknown. METHODS: Three hundred adults with severe aortic stenosis undergoing valve replacement were randomized to receive the Epic (St Jude, St Paul, Minn) (n = 99), Magna (Edwards LifeSciences Inc, Irvine, Calif) (n = 100), or Mitroflow (Sorin Biomedica Spa, Saluggio, Italy) (n = 101) bioprostheses...
January 2015: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/24704946/lipoprotein-a-levels-genotype-and-incident-aortic-valve-stenosis-a-prospective-mendelian-randomization-study-and-replication-in-a-case-control-cohort
#15
Benoit J Arsenault, S Matthijs Boekholdt, Marie-Pierre Dubé, Eric Rhéaume, Nicholas J Wareham, Kay-Tee Khaw, Manjinder S Sandhu, Jean-Claude Tardif
BACKGROUND: Although a previous study has suggested that a genetic variant in the LPA region was associated with the presence of aortic valve stenosis (AVS), no prospective study has suggested a role for lipoprotein(a) levels in the pathophysiology of AVS. Our objective was to determine whether lipoprotein(a) levels and a common genetic variant that is strongly associated with lipoprotein(a) levels are associated with an increased risk of developing AVS. METHODS AND RESULTS: Serum lipoprotein(a) levels were measured in 17 553 participants of the European Prospective Investigation into Cancer (EPIC)-Norfolk study...
June 2014: Circulation. Cardiovascular Genetics
https://www.readbyqxmd.com/read/24534651/comprehensive-hemodynamic-comparison-and-frequency-of-patient-prosthesis-mismatch-between-the-st-jude-medical-trifecta-and-epic-bioprosthetic-aortic-valves
#16
COMPARATIVE STUDY
Ajay Yadlapati, Jimmy Diep, MaryJo Barnes, Tristan Grogan, Daniel M Bethencourt, Gabriel Vorobiof
BACKGROUND: Patient-prosthesis mismatch (PPM) has been reported with a wide range of bioprosthetic valves after aortic valve replacement (AVR) and has been associated with multiple adverse outcomes. The aim of this study was to test the hypothesis that a novel low-profile stented pericardial tissue bioprosthesis for AVR, the Trifecta aortic valve, would have superior hemodynamics, a lower incidence of PPM, and an improvement in clinical outcomes. Its hemodynamic performance was evaluated, and a comparison was performed with a traditional stented pericardial bioprosthesis (Epic) with respect to hemodynamics, PPM, and clinical events...
June 2014: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/23865597/first-quantification-of-alpha-gal-epitope-in-current-glutaraldehyde-fixed-heart-valve-bioprostheses
#17
Filippo Naso, Alessandro Gandaglia, Tomaso Bottio, Vincenzo Tarzia, Mark B Nottle, Anthony J F d'Apice, Peter J Cowan, Emmanuele Cozzi, Cesare Galli, Irina Lagutina, Giovanna Lazzari, Laura Iop, Michele Spina, Gino Gerosa
BACKGROUND: Glutaraldehyde fixation does not guarantee complete tissue biocompatibility in current clinical bioprosthetic heart valves (BHVs). Particularly, circulating anti-αGal human antibodies increase significantly from just 10 days after a BHV implantation. The inactivation of such epitope should be mandatory to meet the requirements for a perspectively safe clinical application; nevertheless, its quantitative assessment in commercially available BHVs has never been carried out...
July 2013: Xenotransplantation
https://www.readbyqxmd.com/read/23847665/one-year-hemodynamic-comparison-of-perimount-magna-with-st-jude-epic-aortic-bioprostheses
#18
Jerzy Bobiarski, Andrew E Newcomb, Abdelsalam M Elhenawy, Manjula Maganti, Joanne Bos, Suzanne Hemeon, Vivek Rao
INTRODUCTION: Cardiac surgeons are using more bioprosthetic valves due to the ageing population as well as to improvements that have been made to these implants. We sought to compare the 1-year hemodynamics of two commercially available valves by echocardiographic parameters. MATERIAL AND METHODS: Retrospective review of our institutional database revealed 69 patients who received either Perimount Magna (n = 33) or St Jude Epic (n = 36) valves in the aortic position with no other valve surgery between June 2004 and March 2006...
June 20, 2013: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/23423937/-endocarditis-caused-by-propionibacterium-acnes-a-diagnostic-and-therapeutic-challenge
#19
T Drosch, M Egle, L Zabel
HISTORY AND ADMISSION FINDINGS: A 77-year-old man suffered from recurrent peripheral cerebral embolisms five months after aortic valve replacement with a bioprosthesis (SJM Epic 25 mm). INVESTIGATIONS: MRT scanning of the brain revealed multiple ischemic areas in different vascular territories. Clinical signs of infective endocarditis were missing and markers of infection were only modestly increased. However, transthoracic echocardiography showed elevated pressure gradients across the bioprosthesis...
March 2013: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/23409363/left-ventricular-mass-regression-is-independent-of-gradient-drop-and-effective-orifice-area-after-aortic-valve-replacement-with-a-porcine-bioprosthesis
#20
MULTICENTER STUDY
Justo Rafael Sádaba, Marie-Christine Herregods, Jan Bogaert, Wolfgang Harringer, Gino Gerosa
BACKGROUND AND AIM OF THE STUDY: The question of whether left ventricular mass (LVM) regression following aortic valve replacement (AVR) is affected by the prosthesis indexed effective orifice area (IEOA) and transprosthetic gradient has not been fully elucidated. Data from a prospective, core-laboratory-reviewed echocardiography and magnetic resonance imaging (MRI) study was used to determine if the degree of LVM regression following AVR with two types of porcine bioprosthesis in patients suffering from predominant aortic valve stenosis (AS) was related to the prosthesis IEOA and transprosthetic gradient...
November 2012: Journal of Heart Valve Disease
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