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https://www.readbyqxmd.com/read/29131326/magnesium-in-migraine-prophylaxis-is-there-an-evidence-based-rationale-a-systematic-review
#1
REVIEW
Alexander von Luckner, Franz Riederer
OBJECTIVE: The primary objective was to systematically evaluate the existing evidence base on magnesium in migraine prophylaxis. METHODS: The search for clinical trials published from 1990 to 2016 was separately conducted by AvL and FR using standard search terms as well as MeSh terms on PubMed and EMBASE. Randomized, double-blind, placebo-controlled trials investigating prophylactic magnesium administration in migraineurs aged 18-65 were considered eligible. In a mutual effort, the studies found were sorted and analyzed under consideration of the guidelines for controlled trials for drugs in migraine by the International Headache Society and using predefined eligibility criteria...
November 13, 2017: Headache
https://www.readbyqxmd.com/read/29093067/practice-guideline-cervical-and-ocular-vestibular-evoked-myogenic-potential-testing-report-of-the-guideline-development-dissemination-and-implementation-subcommittee-of-the-american-academy-of-neurology
#2
Terry D Fife, James G Colebatch, Kevin A Kerber, Krister Brantberg, Michael Strupp, Hyung Lee, Mark F Walker, Eric Ashman, Jeffrey Fletcher, Brian Callaghan, David S Gloss
OBJECTIVE: To systematically review the evidence and make recommendations with regard to diagnostic utility of cervical and ocular vestibular evoked myogenic potentials (cVEMP and oVEMP, respectively). Four questions were asked: Does cVEMP accurately identify superior canal dehiscence syndrome (SCDS)? Does oVEMP accurately identify SCDS? For suspected vestibular symptoms, does cVEMP/oVEMP accurately identify vestibular dysfunction related to the saccule/utricle? For vestibular symptoms, does cVEMP/oVEMP accurately and substantively aid diagnosis of any specific vestibular disorder besides SCDS? METHODS: The guideline panel identified and classified relevant published studies (January 1980-December 2016) according to the 2004 American Academy of Neurology process...
November 1, 2017: Neurology
https://www.readbyqxmd.com/read/29076412/efficacy-duration-and-timing-of-withdrawal-of-prophylactic-treatment-with-antiepileptic-drugs-in-neurosurgical-conditions
#3
Daniel R Calnan, Erin D'Agostino, Matthew R Reynolds, Kimon Bekelis
Seizure control is a critical component of care in many neurosurgical conditions. The development of seizures in patients without a previously identified seizure disorder occurs in a significant proportion of traumatic brain injury, subarachnoid hemorrhage, and brain tumor patients. In this literature review and synthesis, we will discuss the incidence of seizures in selected conditions, indications and evidence for the initiation of antiepileptic drugs (AEDs), suggested duration of usage for AEDs, and current AED guidelines by the American Academy of Neurology (AAN), Congress of Neurological Surgeons (CNS), American Academy of Neurological Surgeons (AANS) and international committees...
October 24, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29074422/suboccipital-craniotomy-versus-craniectomy-a-survey-of-practice-patterns
#4
Elizabeth N Kuhn, Gustavo Chagoya, Bonita S Agee, Mark R Harrigan
OBJECT: Open surgical access to the posterior fossa has traditionally been achieved by permanent bone removal and remains the mainstay of posterior fossa surgery, although craniotomy is an alternative. Considerable variation exists at both the national and international levels within a variety of neurological and neurosurgical disciplines. In this study we surveyed current practice patterns regarding preference of suboccipital craniotomy or craniectomy. METHODS: The membership directory of the American Academy of Neurological Surgeons (AANS) was reviewed...
October 23, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29053896/quality-and-reporting-of-guidelines-on-the-diagnosis-and-management-of-dystonia
#5
Gertrúd Tamás, Catarina Abrantes, Anabela Valadas, Péter Radics, Alberto Albanese, Marina A J Tijssen, Joaquim J Ferreira
BACKGROUND: The quality of clinical practice guidelines on dystonia has not yet been assessed. Our aim was to appraise the methodological quality of guidelines worldwide and analyze the consistency of their recommendations. METHODS: We searched for clinical practice guidelines on dystonia diagnosis/treatment in the National Guideline Clearinghouse, PubMed, National Institute for Health and Care Excellence, Guidelines International Network and Web of Science databases...
October 20, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28978801/metabolic-alterations-in-multiple-sclerosis-and-the-impact-of-vitamin-d-supplementation
#6
Pavan Bhargava, Kathryn C Fitzgerald, Peter A Calabresi, Ellen M Mowry
BACKGROUND: Our goal was to identify changes in the metabolome in multiple sclerosis (MS) and how vitamin D supplementation alters metabolic profiles in MS patients and healthy controls. METHODS: We applied global untargeted metabolomics to plasma from a cross-sectional cohort of age- and sex-matched MS patients and controls and a second longitudinal cohort of MS patients and healthy controls who received 5,000 IU cholecalciferol daily for 90 days. We applied partial least squares discriminant analysis, weighted correlation network analysis (WGCNA), and pathway analysis to the metabolomics data...
October 5, 2017: JCI Insight
https://www.readbyqxmd.com/read/28966734/current-and-future-treatment-options-for-narcolepsy-a-review
#7
Jackie Bhattarai, Scott Sumerall
Narcolepsy is a chronic neurological sleep disorder with potentially disabling symptoms ranging from occupational concerns to mental health difficulties. Recent advances related to the neurobiological basis of narcolepsy have led to newer pharmacological treatment options and adjunctive behavioral techniques that support symptom management. This article outlines evidence-based pharmacologic therapies, behavioral techniques, and psychosocial costs related to narcolepsy. Psychosocial factors, although frequently acknowledged, deserve further attention and awareness from researchers and providers...
January 2017: Sleep Science
https://www.readbyqxmd.com/read/28965527/psychometrics-of-the-aan-caregiver-driving-safety-questionnaire-and-contributors-to-caregiver-concern-about-driving-safety-in-older-adults
#8
Janessa O Carvalho, Beth Springate, Rachel A Bernier, Jennifer Davis
BACKGROUND: The American Academy of Neurology (AAN) updated their practice parameters in the evaluation of driving risk in dementia and developed a Caregiver Driving Safety Questionnaire, detailed in their original manuscript (Iverson Gronseth, Reger, Classen, Dubinsky, & Rizzo, 2010). They described four factors associated with decreased driving ability in dementia patients: history of crashes or citations, informant-reported concerns, reduced mileage, and aggressive driving. METHOD: An informant-reported AAN Caregiver Driving Safety Questionnaire was designed with these elements, and the current study was the first to explore the factor structure of this questionnaire...
October 2, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28931640/qualitative-study-of-burnout-career-satisfaction-and-well-being-among-us-neurologists-in-2016
#9
Janis M Miyasaki, Carol Rheaume, Lisa Gulya, Aviva Ellenstein, Heidi B Schwarz, Thomas R Vidic, Tait D Shanafelt, Terrence L Cascino, Chris M Keran, Neil A Busis
OBJECTIVE: To understand the experience and identify drivers and mitigating factors of burnout and well-being among US neurologists. METHODS: Inductive data analysis was applied to free text comments (n = 676) from the 2016 American Academy of Neurology survey of burnout, career satisfaction, and well-being. RESULTS: Respondents providing comments were significantly more likely to be older, owners/partners of their practice, solo practitioners, and compensated by production than those not commenting...
October 17, 2017: Neurology
https://www.readbyqxmd.com/read/28917084/evaluation-of-neurodevelopment-of-children-with-congenital-hypothyroidism-by-the-denver-developmental-screening-test
#10
Ayşe Derya Buluş, Esra Tiftik
BACKGROUND: Thyroid hormones are essential for growth and brain development in childhood. Although congenital hypothyroidism (CH) is the most common reason for mental retardation, normal neurological development can be achieved through early and effective treatment. The aim of the present study was to evaluate the neurological development of CH patients aged 24-56 months. METHODS: The study included a total of 116 healthy control subjects and 112 patients aged 24-56 months who were diagnosed with CH during the neonatal period and were being followed up at the Pediatric Endocrinology Department, Keçiören Training and Research Hospital, between 2012 and 2015...
October 26, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28859696/a-systematic-review-of-evidence-for-fitness-to-drive-among-people-with-the-mental-health-conditions-of-schizophrenia-stress-anxiety-disorder-depression-personality-disorder-and-obsessive-compulsive-disorder
#11
Carolyn A Unsworth, Anne M Baker, Man H So, Priscilla Harries, Desmond O'Neill
BACKGROUND: Limited evidence exists regarding fitness-to-drive for people with the mental health conditions of schizophrenia, stress/anxiety disorder, depression, personality disorder and obsessive compulsive disorder (herein simply referred to as 'mental health conditions'). The aim of this paper was to systematically search and classify all published studies regarding driving for this population, and then critically appraise papers addressing assessment of fitness-to-drive where the focus was not on the impact of medication on driving...
August 31, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28845859/-the-new-frontiers-of-patent-foramen-ovale
#12
Maria Elena Di Salvo, Fabio Maria Santagati, Piera Capranzano, Corrado Tamburino
Several evidences support the hypothesis that patent foramen ovale (PFO), especially when associated with specific anatomical features, relates to an increased incidence of paradoxical embolism including ischemic stroke. According to current guidelines, clinicians may offer percutaneous closure of PFO in rare circumstances, such as recurrent strokes despite adequate medical therapy with no other mechanism identified (American Academy of Neurology 2016) or deep venous thrombosis at high risk of recurrence (American Heart Association/American Stroke Association 2014)...
September 2017: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/28819801/botulinum-toxin-treatment-in-multiple-sclerosis-a-review
#13
REVIEW
Yasaman Safarpour, Tahereh Mousavi, Bahman Jabbari
Purpose of review The purpose of this review is to provide updated information on the role of botulinum neurotoxin (BoNT) therapy in multiple sclerosis (MS). This review aims to answer which symptoms of multiple sclerosis may be amenable to BoNT therapy. Recent findings We searched the literature on the efficacy of BoNTs for treatment of MS symptoms up to April 1st 2017 via the Yale University Library's search engine including but not limited to Pub Med and Ovis SP. The level of efficacy was defined according to the assessment's criteria set forth by the Subcommittee on Guideline Development of the American Academy of Neurology...
August 17, 2017: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/28777178/sleep-disordered-breathing
#14
Nancy R Foldvary-Schaefer, Tina E Waters
PURPOSE OF REVIEW: Sleep-disordered breathing encompasses a broad spectrum of sleep-related breathing disorders, including obstructive sleep apnea (OSA), central sleep apnea, as well as sleep-related hypoventilation and hypoxemia. Diagnostic criteria have been updated in the International Classification of Sleep Disorders, Third Edition and the American Academy of Sleep Medicine Manual for Scoring Sleep and Associated Events. Neurologic providers should have basic knowledge and skills to identify at-risk patients, as these disorders are associated with substantial morbidity, the treatment of which is largely reversible...
August 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28768842/developing-an-outline-for-teleneurology-curriculum-aan-telemedicine-work-group-recommendations
#15
Raghav Govindarajan, Eric R Anderson, Roger R Hesselbrock, Ramesh Madhavan, Lauren R Moo, Nima Mowzoon, James Otis, Mark N Rubin, Madhu Soni, Jack W Tsao, Scott Vota, Hannah Planalp
The emerging field of teleneurology is delivering quality care to neurologic patients in increasingly numerous technologies and configurations. Teleneurology is well-positioned to address many of the logistical issues neurologists and their patients encounter today. However, formalized medical training has not caught up with this developing field, and there is a lack of formal education concentrating on the specific opportunities and challenges of teleneurology. Considering this, the American Academy of Neurology Telemedicine Work Group identified equivalencies with which any practitioner of teleneurology should be familiar...
August 29, 2017: Neurology
https://www.readbyqxmd.com/read/28684957/practice-guideline-summary-sudden-unexpected-death-in-epilepsy-incidence-rates-and-risk-factors-report-of-the-guideline-development-dissemination-and-implementation-subcommittee-of-the-american-academy-of-neurology-and-the-american-epilepsy-society
#16
Cynthia Harden, Torbjörn Tomson, David Gloss, Jeffrey Buchhalter, J Helen Cross, Elizabeth Donner, Jacqueline A French, Anthony Gil-Nagel, Dale C Hesdorffer, W Henry Smithson, Mark C Spitz, Thaddeus S Walczak, Josemir W Sander, Philippe Ryvlin
OBJECTIVE: To determine the incidence rates of sudden unexpected death in epilepsy (SUDEP) in different epilepsy populations and address the question of whether risk factors for SUDEP have been identified. METHODS: Systematic review of evidence; modified Grading Recommendations Assessment, Development and Evaluation process for developing conclusions; recommendations developed by consensus. RESULTS: Findings for incidence rates based on 12 Class I studies include the following: SUDEP risk in children with epilepsy (aged 0-17 years) is 0...
May 2017: Epilepsy Currents
https://www.readbyqxmd.com/read/28667180/burnout-career-satisfaction-and-well-being-among-us-neurology-residents-and-fellows-in-2016
#17
Kerry H Levin, Tait D Shanafelt, Christopher M Keran, Neil A Busis, Laura A Foster, Jennifer Rose V Molano, Cormac A O'Donovan, Jeffrey B Ratliff, Heidi B Schwarz, Jeff A Sloan, Terrence L Cascino
OBJECTIVE: To study prevalence of and factors contributing to burnout, career satisfaction, and well-being in US neurology residents and fellows. METHODS: A total of 938 US American Academy of Neurology member neurology residents and fellows were surveyed using standardized measures of burnout, career satisfaction, and well-being from January 19 to March 21, 2016. RESULTS: Response rate was 37.7% (354/938); about 2/3 of responders were residents and 1/3 were fellows...
August 1, 2017: Neurology
https://www.readbyqxmd.com/read/28659011/using-social-exchange-theory-to-understand-non-terminal-palliative-care-referral-practices-for-parkinson-s-disease-patients
#18
Lindsay P Prizer, Jennifer L Gay, Molly M Perkins, Mark G Wilson, Kerstin G Emerson, Anne P Glass, Janis M Miyasaki
BACKGROUND: A palliative approach is recommended in the care of Parkinson's disease patients; however, many patients only receive this care in the form of hospice at the end of life. Physician attitudes about palliative care have been shown to influence referrals for patients with chronic disease, and negative physician perceptions may affect early palliative referrals for Parkinson's disease patients. AIM: To use Social Exchange Theory to examine the association between neurologist-perceived costs and benefits of palliative care referral for Parkinson's disease patients and their reported referral practices...
March 1, 2017: Palliative Medicine
https://www.readbyqxmd.com/read/28650882/diagnostic-utility-of-intraoperative-neurophysiological-monitoring-for-intramedullary-spinal-cord-tumors-systematic-review-and-meta-analysis
#19
Tej D Azad, Arjun V Pendharkar, Viet Nguyen, James Pan, Ian D Connolly, Anand Veeravagu, Rita Popat, John K Ratliff, Gerald A Grant
STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVE: The aim of this study was to systematically evaluate the diagnostic utility of intraoperative neurophysiological monitoring (IONM) for detecting postoperative injury in resection of intramedullary spinal cord tumors (IMSCT). SUMMARY OF BACKGROUND DATA: Surgical management of IMSCT can involve key neurological and vascular structures. IONM aims to assess the functional integrity of susceptible elements in real time...
June 23, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28650249/inpatient-admissions-and-costs-associated-with-persistent-use-of-dalfampridine-extended-release-in-multiple-sclerosis-a-claims-database-analysis
#20
Amy Guo, Alexander Niyazov, Dendy Macaulay, Emi Terasawa, Luke Schmerold, Eric Q Wu, Stephen Krieger
BACKGROUND: While the clinical benefits of dalfampridine extended-release (D-ER) have been established in patients with multiple sclerosis (MS) through multiple clinical trials, there is limited real-world data on D-ER use, in particular the persistent use of D-ER, and associated acute care resource utilization and costs. OBJECTIVE: To examine the real-world association of D-ER use and inpatient admissions and costs among patients with MS. METHODS: This study was a retrospective observational claims analysis of the MarketScan database (April 2009-March 2014)...
July 2017: Journal of Managed Care & Specialty Pharmacy
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