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https://www.readbyqxmd.com/read/29779123/pulmonary-valve-replacement-after-repaired-tetralogy-of-fallot
#1
REVIEW
Hideki Tatewaki, Akira Shiose
In this review article, we describe pulmonary valve replacement (PVR) late after repaired Tetralogy of Fallot (TOF). Since the introduction of surgical intervention for patients with TOF in 1945, surgical management of TOF has dramatically improved early survival with mortality rates, less than 2-3%. However, the majority of these patients continue to experience residual right ventricular outflow tract pathology, most commonly pulmonary valve regurgitation (PR). The patients are generally asymptomatic during childhood and adolescence and, however, are at risk for severe PR later which can result in exercise intolerance, heart failure, arrhythmias, and sudden death...
May 19, 2018: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29777556/electrophysiology-and-structural-interventions-in-adults-with-congenital-heart-disease-comparison-of-combined-versus-separate-procedures
#2
Ian Lindsay, Farnoosh Nik-Ahd, Jamil A Aboulhosn, Jeremy P Moore
BACKGROUND: Electrophysiologic (EP) and structural interventions in adult congenital heart disease (ACHD) are typically completed during separate hospital encounters. With planning/coordination, these cases can be combined. OBJECTIVES: We hypothesized that this integrated approach would yield patient and health system benefits. METHODS: Consecutive ACHD patients undergoing combined interventions were matched to controls with identical but separate procedures...
May 18, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29776810/congenital-heart-disease-in-adults-assessmentof-functional-capacity-using-cardiopulmonary-exercise-testing
#3
Sílvia Aguiar Rosa, Ana Agapito, Rui M Soares, Lídia Sousa, José Alberto Oliveira, Ana Abreu, Ana Sofia Silva, Sandra Alves, Helena Aidos, Fátima F Pinto, Rui Cruz Ferreira
AIM: The aim of the study was to compare functional capacity in different types of congenital heart disease (CHD), as assessed by cardiopulmonary exercise testing (CPET). METHODS: A retrospective analysis was performed of adult patients with CHD who had undergone CPET in a single tertiary center. Diagnoses were divided into repaired tetralogy of Fallot, transposition of the great arteries (TGA) after Senning or Mustard procedures or congenitally corrected TGA, complex defects, shunts, left heart valve disease and right ventricular outflow tract obstruction...
May 15, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29769202/predictors-of-length-of-hospital-stay-after-complete-repair-for-tetralogy-of-fallot-a-prospective-cohort-study
#4
Laura Mercer-Rosa, Okan U Elci, Grace DeCost, Stacy Woyciechowski, Sharon M Edman, Chitra Ravishankar, Christopher E Mascio, Steven M Kawut, Elizabeth Goldmuntz
BACKGROUND: We sought to identify patient and surgical factors associated with time to hospital discharge in patients undergoing complete repair for tetralogy of Fallot. METHODS AND RESULTS: We performed a prospective cohort study of patients with tetralogy of Fallot admitted for complete repair between May 1, 2012 and June 2, 2017 at Children's Hospital of Philadelphia with detailed demographic, clinical, and operative characteristics. The primary outcome was time to hospital discharge...
May 16, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29767292/short-axis-diastolic-ventricular-area-ratio-as-a-new-index-in-screening-patients-with-repaired-tetralogy-of-fallot
#5
Dala Zakaria, Sean Lang, Mallikarjuna Rettiganti, Jeffrey M Gossett, Elijah Bolin, R Thomas Collins
Right ventricular (RV) end-diastolic volume measured by cardiovascular magnetic resonance imaging (CMR) is a criterion for pulmonary valve replacement in patients with tetralogy of Fallot (TOF). We sought to determine if the ratio of echocardiographic, short-axis RV-to-left ventricular (LV) end-diastolic areas (EDA) could be used to predict RV volume on CMR. We retrospectively reviewed the echocardiograms of all patients with repaired TOF who underwent CMR at our institution from 2011 to 2015 and also had an echocardiogram within 6 months of the CMR...
May 16, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29762087/genomics-and-epigenomics-of-congenital-heart-defects-expert-review-and-lessons-learned-in-africa
#6
Nicholas Ekow Thomford, Kevin Dzobo, Nana Akyaa Yao, Emile Chimusa, Jonathan Evans, Emmanuel Okai, Paul Kruszka, Maximilian Muenke, Gordon Awandare, Ambroise Wonkam, Collet Dandara
Congenital heart defects (CHD) are structural malformations found at birth with a prevalence of 1%. The clinical trajectory of CHD is highly variable and thus in need of robust diagnostics and therapeutics. Major surgical interventions are often required for most CHDs. In Africa, despite advances in life sciences infrastructure and improving education of medical scholars, the limited clinical data suggest that CHD detection and correction are still not at par with the rest of the world. But the toll and genetics of CHDs in Africa has seldom been systematically investigated...
May 2018: Omics: a Journal of Integrative Biology
https://www.readbyqxmd.com/read/29761422/computational-pre-surgical-planning-of-arterial-patch-reconstruction-parametric-limits-and-in-vitro-validation
#7
S Samaneh Lashkarinia, Senol Piskin, Tijen A Bozkaya, Ece Salihoglu, Can Yerebakan, Kerem Pekkan
Surgical treatment of congenital heart disease (CHD) involves complex vascular reconstructions utilizing artificial and native surgical materials. A successful surgical reconstruction achieves an optimal hemodynamic profile through the graft in spite of the complex post-operative vessel growth pattern and the altered pressure loading. This paper proposes a new in silico patient-specific pre-surgical planning framework for patch reconstruction and investigates its computational feasibility. The proposed protocol is applied to the patch repair of main pulmonary artery (MPA) stenosis in the Tetralogy of Fallot CHD template...
May 14, 2018: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/29760475/computed-tomography-for-evaluating-right-ventricle-and-pulmonary-artery-in-pediatric-tetralogy-of-fallot-correlation-with-post-operative-pulmonary-regurgitation
#8
Yue Gao, Zhi-Gang Yang, Ke Shi, Kai-Yue Diao, Hua-Yan Xu, Ying-Kun Guo
Pulmonary regurgitation (PR) is the most common complication after tetralogy of Fallot (TOF) surgical repair, and long-term PR might result in cardiovascular events. The aim of this study was to assess the influence of pre-operative right ventricle (RV) and pulmonary artery (PA) parameters assessed by dual-source computed tomography on post-operative PR. A total of 41 TOF patients who underwent trans-valve surgical repair were retrospectively recruited. The RV and PA parameters evaluated by pre-operative DSCT were compared between the PR and non-PR groups...
May 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29753092/sex-differences-for-major-congenital-heart-defects-in-down-syndrome-a-population-based-study
#9
Michele Santoro, Alessio Coi, Isabella Spadoni, Fabrizio Bianchi, Anna Pierini
BACKGROUND: Down syndrome (DS) is the most common autosomal chromosomal anomaly in liveborn infants. About 40% of infants with DS have a major congenital heart defect (CHD). Among them, atrioventricular septal defects (AVSD), atrial septal defects (ASD), ventricular septal defect (VSD) and Tetralogy of Fallot (ToF) are the most common. The aim of this study was to estimate the sex difference in the occurrence of CHD in infants with DS comparing it with non-DS infants. METHOD: Live birth cases of DS diagnosed by the first year of life were extracted from the Registry of Congenital Anomalies of Tuscany (2003-2015 period)...
May 9, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29751199/intrapericardial-gossypiboma-rare-cause-of-intrathoracic-mass
#10
Anil Kumar, Shiv Shankar Paswan, Rajinder Prashad, Rekha Kumari, Bindey Kumar
INTRODUCTION: Gossypiboma is a retained surgical sponge inside our body after surgical intervention. It is most commonly found in abdominal cavity. Its occurrence in thoracic cavity as intrapericardial gossypiboma is extremely rare. PRESENTATION OF CASE: We present a 25 year old male with complaint of chest pain for 1 year. He had a history of total correction of Tetralogy of fallot 14 years back, at another hospital. On clinical examination and investigations including contrast enhanced computed tomography (CECT) of thorax; diagnosis of right anterior mediastinal mass of germ cell tumor was made and planned for thoracotomy...
May 3, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29748395/considerations-in-pursuing-the-optimal-timing-for-pulmonary-valve-replacement-in-repaired-tetralogy-of-fallot
#11
Kai Ma, Guanxi Wang, Shoujun Li
No abstract text is available yet for this article.
June 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29739232/comparison-of-the-coagulation-effect-achieved-by-octaplaslg-versus-fresh-frozen-plasma-in-pediatric-cardiac-surgical-patients
#12
Amanpreet S Kalsi, Omar Al-Azzawi, Ravi Gill
OctaplasLG is indicated for use in patients undergoing cardiac surgery who require replacement of multiple clotting factors. The use of OctaplasLG over single-donor fresh frozen plasma (FFP) may have beneficial effects when considering the transmission of enveloped viruses. Additionally, it has the potential for fewer adverse reactions, reduced disease transmission, and a more homogenous coagulation factor composition. However, its efficacy and safety have not yet been evaluated in the pediatric population...
January 1, 2018: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/29738469/the-role-of-scarnas-in-adjusting-alternative-mrna-splicing-in-heart-development
#13
REVIEW
Chloe Nagasawa, Allison Ogren, Nataliya Kibiryeva, Jennifer Marshall, James E O'Brien, Naoya Kenmochi, Douglas C Bittel
Congenital heart disease (CHD) is a leading cause of death in children <1 year of age. Despite intense effort in the last 10 years, most CHDs (~70%) still have an unknown etiology. Conotruncal based defects, such as Tetralogy of Fallot (TOF), a common complex of devastating heart defects, typically requires surgical intervention in the first year of life. We reported that the noncoding transcriptome in myocardial tissue from children with TOF is characterized by significant variation in levels of expression of noncoding RNAs, and more specifically, a significant reduction in 12 small cajal body-associated RNAs (scaRNAs) in the right ventricle...
May 8, 2018: Journal of Cardiovascular Development and Disease
https://www.readbyqxmd.com/read/29731834/diagnosis-and-treatment-of-postoperative-intestinal-perforation-in-infants-and-young-children-with-congenital-heart-disease-a-report-of-three-cases
#14
Yong-Hong Zhang, Zhen-Liang Chen, Lei Shi, Zhong-Jian Chen, Xiang-Yang Dong, Bo Zhai
The aim of the present study was to analyze risk factors of intestinal perforation following surgery for the treatment of congenital heart disease in infants and young children, and to summarize experiences of diagnosis and treatment. A total of 3,270 children, who underwent congenital heart disease surgery under extracorporeal circulation from January 2010 to July 2015, were retrospectively analyzed. Among these children, three (0.09%) developed postoperative intestinal perforation. Primary diseases were Tetralogy of Fallot (two cases) and ventricular septal defect combined with atrial septal defect (one case)...
May 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29731786/an-update-work-of-pulse-oximetry-screening-for-detecting-critical-congenital-heart-disease-in-the-newborn
#15
A Taksande, R Meshram, A Lohakare, S Purandare, U Biyani, J Vagha
Background: Congenital Heart Disease (CHD) is the commonest group of congenital malformations and affects 7-8 per 1000 live born newborns. Nevertheless, it is estimated that more than 50% of babies with undiagnosed CHD are not detected by routine neonatal cardiac examination. Aim: To find the incidence of CHD in newborns and to determine the accuracy of pulse oximetry for detecting clinically unrecognized critical congenital heart disease (CCHD) in the newborns...
July 2017: Images in Paediatric Cardiology
https://www.readbyqxmd.com/read/29720396/primary-repair-versus-surgical-and-transcatheter-palliation-in-infants-with-tetralogy-of-fallot
#16
Dan M Dorobantu, Alireza S Mahani, Mansour T A Sharabiani, Ragini Pandey, Gianni D Angelini, Andrew J Parry, Robert M R Tulloh, Robin P Martin, Serban C Stoica
OBJECTIVES: Treatment of infants with tetralogy of Fallot (ToF) has evolved in the last two decades with increasing use of primary surgical repair (PrR) and transcatheter right ventricular outflow tract palliation (RVOTd), and fewer systemic-to-pulmonary shunts (SPS). We aim to report contemporary results using these treatment options in a comparative study. METHODS: This a retrospective study using data from the UK National Congenital Heart Disease Audit. All infants (n=1662, median age 181 days) with ToF and no other complex defects undergoing repair or palliation between 2000 and 2013 were considered...
May 2, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29719804/unilateral-pulmonary-artery-agenesis-an-unusual-cause-of-unilateral-ards
#17
Lakshmi Saladi, Swati Roy, Gilda Diaz-Fuentes
Unilateral pulmonary artery agenesis (UPAA) is a rare malformation that can present as an isolated anomaly or may be associated with certain congenital cardiac anomalies, such as tetralogy of Fallot, atrial septal defect, coarctation of aorta, right aortic arch, truncus arteriosus and pulmonary atresia. Clinical presentation is non-specific which makes the diagnosis elusive; chronic dyspnea, hemoptysis or recurrent infections are the most common manifestations. Patients may remain asymptomatic until adulthood...
2018: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/29712484/does-prenatal-diagnosis-of-critical-congenital-heart-diseases-influence-the-prereferral-mortality-in-a-center-without-surgical-intervention
#18
Buse Özer Bekmez, Evrim Alyamaç Dizdar, Nilüfer Okur, Mehmet Büyüktiryaki, Nurdan Uraş, Serife Suna Oğuz
BACKGROUND: Prenatal diagnosis ameliorates some preoperative and postoperative outcomes in critical congenital heart disease (CHD). Despite large variability among anatomical defect types, nearly half of them are diagnosed antenatally. We aimed to investigate the effect of the antenatal diagnosis on prereferral mortality of infants with critical CHD in a center without cardiovascular surgery clinic. METHODS: Medical records of the neonates who were diagnosed with critical CHD between the years 2010 and 2016 in Zekai Tahir Burak Women's health Education and Research Hospital were retrospectively reviewed for the study...
April 30, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29706570/tetralogy-of-fallot-perioperative-management-and-analysis-of-outcomes
#19
REVIEW
Matthew M Townsley, Jimmy Windsor, David Briston, Jorge Alegria, Harish Ramakrishna
No abstract text is available yet for this article.
March 24, 2018: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29697045/an-unexpected-case-of-post-operative-superior-caval-vein-syndrome
#20
Lynn Peng, Lisa Wise-Faberowski
Superior caval vein obstruction in children after congenital heart surgery has been more associated with thrombosis formation as result of single-ventricle palliation, infection, indwelling devices/catheters, or external compression. Many of these patients will present to the cardiac catheterisation laboratory for evaluation and possible intervention. We present an unusual case of superior caval vein obstruction in a patient after Tetralogy of Fallot repair.
April 26, 2018: Cardiology in the Young
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