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https://www.readbyqxmd.com/read/29159852/orbital-invasive-squamous-cell-carcinoma-with-adnexal-involvement-clinically-mimicking-feline-restrictive-orbital-myofibroblastic-sarcoma-19-cases-1990-2016
#1
Kathryn A Diehl, Silvia G Pryor, Leandro Bc Teixeira
OBJECTIVE: To describe the clinical presentations of patients diagnosed with ocular adnexal or orbital squamous cell carcinoma (SCC), which possess features similar to feline restrictive orbital myofibroblastic sarcoma (FROMS). PROCEDURES: A retrospective review of adnexal and/or orbital SCC was performed. Cases were collected from the University of Georgia College of Veterinary Medicine and the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW) (1990-2016)...
November 21, 2017: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/29153104/development-and-preliminary-psychometric-evaluation-of-an-owner-completed-measure-of-feline-quality-of-life
#2
Sophi Tatlock, Margaret Gober, Nicola Williamson, Rob Arbuckle
Due to improved healthcare and pet longevity, measurement of health-related quality of life (HRQoL) is increasingly important in companion animal medicine. The aim of this study was to develop and evaluate the content and psychometric properties of an owner-completed assessment of health and quality of life (QoL) in cats for use in general veterinary clinical practice. A 23-item feline QoL measure, drafted based on findings from an online survey completed by 45 pet owners, was revised following qualitative interviews with 10 pet owners of healthy cats to assess content validity...
October 2017: Veterinary Journal
https://www.readbyqxmd.com/read/29056740/the-use-of-recombinant-feline-interferon-omega-therapy-as-an-immune-modulator-in-cats-naturally-infected-with-feline-immunodeficiency-virus-new-perspectives
#3
REVIEW
Rodolfo Oliveira Leal, Solange Gil
Type I interferons (IFNs) are well-known cytokines that, among their main functions, are key components of the host immune response against viral infections. Due to its immune modulation properties, they are commonly used in the therapeutic approach of various retroviral infections, namely human immunodeficiency virus (HIV) and feline immunodeficiency virus (FIV). In HIV infection, it has been shown that IFN therapy limits early viral replication, particularly useful on post-exposure prophylaxis. In veterinary medicine, recombinant feline interferon omega (rFeIFN-ω) was the first interferon licensed for use in cats...
October 27, 2016: Veterinary Sciences
https://www.readbyqxmd.com/read/29056666/the-comparative-value-of-feline-virology-research-can-findings-from-the-feline-lentiviral-vaccine-be-translated-to-humans
#4
REVIEW
Margaret J Hosie, Navapon Techakriengkrai, Paweł M Bęczkowski, Matthew Harris, Nicola Logan, Brian J Willett
Feline immunodeficiency virus (FIV) is a lentivirus of domestic cats that shares several similarities with its human counterpart, human immunodeficiency virus (HIV). Their analogies include genomic organization, lymphocyte tropism, viral persistence and induction of immunodeficiency. FIV is the only lentivirus for which a commercial vaccine is registered for prevention in either human or veterinary medicine. This provides a unique opportunity to investigate the mechanisms of protection induced by lentivirus vaccines at the population level and might contribute to the development of efficacious HIV vaccines...
January 28, 2017: Veterinary Sciences
https://www.readbyqxmd.com/read/29033910/resistance-of-animal-strains-of-pseudomonas-aeruginosa-to-carbapenems
#5
Marisa Haenni, Maxime Bour, Pierre Châtre, Jean-Yves Madec, Patrick Plésiat, Katy Jeannot
Carbapenems are major antibiotics reserved to human medicine. This study aimed to investigate the mechanisms of carbapenem resistance of a selection of Pseudomonas aeruginosa veterinary strains from the French network Resapath. Thirty (5.7%) imipenem and/or meropenem non-susceptible P. aeruginosa of canine (n = 24), feline (n = 5), or bovine (n = 1) origin were identified in a large collection of 527 veterinary strains gathered by the Resapath. These resistant isolates belonged to 25 MultiLocus Sequence Types (MLST), of which 17 (68%) are shared with clinical (human) strains, such as high risk clones ST233 and ST395...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28955476/periaortic-lymphoma-in-a-cat
#6
Laura Bree, Chiara Bergamino, Ronan Mullins, Pamela Kelly, Robert Shiel
CASE SUMMARY: A 14-year-old neutered male Siamese cat was presented with a 3 month history of lethargy, inappetence, dehydration, hindlimb ataxia and intermittent proprioceptive deficits in the hindlimbs. Physical examination revealed low body condition score (1.75/5), pallor and bilateral basilar grade II/VI systolic heart murmur. Neurological examination revealed hindlimb ataxia, severe atrophy of the hindlimb musculature, intermittent hindlimb proprioceptive deficits and normoreflexia...
July 2017: JFMS open reports
https://www.readbyqxmd.com/read/28955475/single-pedicle-hinge-flap-performed-by-shelter-medicine-team-resolves-chronic-antebrachial-wound-in-a-cat
#7
Jodi M Richardson, Jacob M Shivley, Philip A Bushby
CASE SUMMARY: An approximately 3-year-old, male domestic longhair cat was presented to a mobile veterinary unit for routine neuter. Preoperative physical examination revealed an approximately 5 cm × 2 cm scab on the craniolateral portion of the left antebrachium. The cat was anesthetized for the neuter using an injectable anesthesia protocol. After castration, the wound area on the antebrachium was clipped, copiously lavaged and the wound edges were surgically debrided. Injectable antibiotics and analgesic management were instituted...
July 2017: JFMS open reports
https://www.readbyqxmd.com/read/28892209/pharmacokinetics-of-mycophenolic-acid-after-intravenous-administration-of-mycophenolate-mofetil-to-healthy-cats
#8
J E Slovak, S M Rivera, J K Hwang, M H Court, N F Villarino
BACKGROUND: Mycophenolate mofetil (MMF), the prodrug of mycophenolic acid (MPA), is becoming increasingly popular as an alternative immunosuppressant in feline medicine. Pharmacokinetic information is not available for cats. OBJECTIVE: The purpose of this study was to determine whether MMF is biotransformed into the active metabolite MPA and to evaluate the disposition of MPA after a 2-hour constant rate intravenous (IV) infusion of MMF in healthy cats. ANIMALS: Healthy cats (n = 6)...
September 11, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28807033/sponsorship-bias-and-quality-of-randomised-controlled-trials-in-veterinary-medicine
#9
K J Wareham, R M Hyde, D Grindlay, M L Brennan, R S Dean
BACKGROUND: Randomised controlled trials (RCTs) are considered the gold standard form of evidence for assessing treatment efficacy, but many factors can influence their reliability including methodological quality, reporting quality and funding source. The aim of this study was to examine the relationship between funding source and positive outcome reporting in veterinary RCTs published in 2011 and to assess the risk of bias in the RCTs identified. METHODS: A structured search of PubMed was used to identify feline, canine, equine, bovine and ovine clinical trials examining the efficacy of pharmaceutical interventions published in 2011...
August 14, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28804855/human-heart-failure-with-preserved-ejection-versus-feline-cardiomyopathy-what-can-we-learn-from-both-veterinary-and-human-medicine
#10
REVIEW
Valentine Prat, Bertrand Rozec, Chantal Gauthier, Benjamin Lauzier
Cardiovascular affections are a growing health burden in human populations. Recent advances in cardiology have improved treatments and outcomes for myocardial infarction and arrhythmias, but other conditions still remain poorly understood. To date, the classical approach to study cardiovascular diseases involves rodent models, despite their strong differences with human cardiac physiology. In this context, this review will focus on the common traits between human and feline cardiac diseases, namely heart failure with preserved ejection fraction and feline cardiomyopathies, respectively...
November 2017: Heart Failure Reviews
https://www.readbyqxmd.com/read/28705248/prevention-of-feline-leishmaniosis-with-an-imidacloprid-10-flumethrin-4-5-polymer-matrix-collar
#11
Emanuele Brianti, Luigi Falsone, Ettore Napoli, Gabriella Gaglio, Salvatore Giannetto, Maria Grazia Pennisi, Vito Priolo, Maria Stefania Latrofa, Viviana Domenica Tarallo, Fabrizio Solari Basano, Roberto Nazzari, Katrin Deuster, Matthias Pollmeier, Laura Gulotta, Vito Colella, Filipe Dantas-Torres, Gioia Capelli, Domenico Otranto
BACKGROUND: Leishmaniosis caused by Leishmania infantum is one of the most important vector-borne diseases affecting animals and humans worldwide. Dogs are considered main reservoirs of the zoonotic forms, though in the last years the role of cats as reservoirs has been increasingly investigated. Feline leishmaniosis (FeL) occurs in endemic areas and no specific preventive measures have been investigated so far. In this study the efficacy of a 10% imidacloprid/4.5% flumethrin polymer matrix collar, licensed for tick and flea prevention, has been assessed against FeL in a longitudinal study on 204 privately owned cats from the Aeolian islands (Sicily), an area highly endemic for the disease...
July 14, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28675320/flow-cytometry-for-feline-lymphoma-a-retrospective-study-regarding-pre-analytical-factors-possibly-affecting-the-quality-of-samples
#12
Valeria Martini, Serena Bernardi, Priscilla Marelli, Marzia Cozzi, Stefano Comazzi
Objectives Flow cytometry (FC) is becoming increasingly popular among veterinary oncologists for the diagnosis of lymphoma or leukaemia. It is accurate, fast and minimally invasive. Several studies on FC have been carried out in canine oncology and applied with great results, whereas there is limited knowledge and use of this technique in feline patients. This is mainly owing to the high prevalence of intra-abdominal lymphomas in this species and the associated difficulty in the diagnostic procedures needed to collect the sample...
July 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28673194/evaluation-of-ctad-citrate-theophylline-adenosine-dipyridamole-as-a-universal-anticoagulant-in-dogs
#13
Fanny A Granat, Anne Geffré, Laetitia A Lucarelli, Jean-Pierre D Braun, Catherine Trumel, Nathalie H Bourgès-Abella
CTAD (citrate-theophylline-adenosine-dipyridamole) has been shown to be an almost universal anticoagulant in human and feline medicine, allowing most hematology, coagulation, and biochemical analyses. Forty canine blood specimens were collected in CTAD, EDTA, heparin, and citrate for hematology, biochemistry, and coagulation analyses. CTAD partially limited platelet aggregation observed in EDTA blood smears. CTAD specimens gave similar and well-correlated results for most variables of a complete blood cell count, except for mean corpuscular volume, which was moderately higher, and mean corpuscular hemoglobin concentration, which was moderately lower in CTAD than in EDTA; reticulocyte and platelet indexes were poorly correlated...
June 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28671494/stakeholder-expectations-regarding-the-ability-of-new-veterinary-graduates-to-perform-various-diagnostic-and-surgical-procedures
#14
Julie A Cary, Chelsea H Farnsworth, John Gay, Hillary S Carroll
OBJECTIVE To assess stakeholders' expectations regarding new veterinary graduates' ability to perform various diagnostic and surgical procedures. DESIGN Cross-sectional survey. SAMPLE Veterinary students, recent graduates, clinical veterinary college faculty, and general practitioners at or from AVMA Council on Education-accredited colleges of veterinary medicine in the United States and Caribbean. PROCEDURES Respondents rated how proficient they expected new graduates, on their first day of practice, to be in 8 diagnostic procedures and the degree of independence they expected of new graduates in 8 surgical procedures...
July 15, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28651614/3d-chick-embryo-chorioallantoic-membrane-model-as-an-in-vivo-model-to-study-morphological-and-histopathological-features-of-feline-fibrosarcomas
#15
Katarzyna Zabielska-Koczywąs, Agata Wojtkowska, Izabella Dolka, Anna Małek, Magdalena Walewska, Anna Wojtalewicz, Artur Żbikowski, Roman Lechowski
BACKGROUND: The chick embryo chorioallantoic membrane (CAM) model is well described in human medicine as a cost-effective, easy to perform preclinical oncological model for observing pro- and antiangiogenic response, tumor biology and metastasis. The main objective of this article was to present the modification of the CAM assay in order to evaluate tumor growth from two feline fibrosarcoma cell lines (FFS1, FFS3) and describe their morphological and histopathological features. RESULTS: The authors described morphological and histopathological features of two feline fibrosarcoma cell lines (FFS1 and FFS3) grown on the CAM...
June 26, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28618186/therapeutic-efficacy-of-fresh-allogeneic-mesenchymal-stem-cells-for-severe-refractory-feline-chronic-gingivostomatitis
#16
Boaz Arzi, Kaitlin C Clark, Ayswarya Sundaram, Mathieu Spriet, Frank J M Verstraete, Naomi J Walker, Megan R Loscar, Nasim Fazel, William J Murphy, Natalia Vapniarsky, Dori L Borjesson
Mesenchymal stem cells (MSCs) have potent immunomodulatory functions and are a promising therapy for immune-mediated inflammatory disorders. We previously demonstrated the efficacy of fresh, autologous, adipose-derived MSCs (ASCs) to treat feline chronic gingivostomatitis (FCGS), a chronic oral mucosal inflammatory disease similar to human oral lichen planus. Here, we investigate the use of fresh allogeneic ASCs for treatment of FCGS in seven cats. Radiolabeled ASCs were also tracked systemically. Each cat received two intravenous injections of 20 million ASCs, 1 month apart...
August 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28592225/diagnostic-bone-marrow-sampling-in-cats
#17
REVIEW
Christopher G Byers
Practical relevance: Hematologic disorders are relatively common in cats, as inflammatory, immune-mediated and infectious diseases have the potential to impact erythroid, myeloid and thrombopoietic lines within the bone marrow. Clinical challenges: Clinicians often benefit from information obtained from bone marrow cytology and histopathology in diagnosing hematologic disorders in feline patients. However, these sampling procedures are ones that many veterinarians are intimidated by and thus not comfortably performing in clinical practice...
July 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28509634/vitamin-d-metabolism-in-canine-and-feline-medicine
#18
Valerie J Parker, Adam J Rudinsky, Dennis J Chew
No abstract text is available yet for this article.
June 1, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28499392/experimental-tumor-growth-of-canine-osteosarcoma-cell-line-on-chick-embryo-chorioallantoic-membrane-in-vivo-studies
#19
Magdalena Walewska, Izabella Dolka, Anna Małek, Anna Wojtalewicz, Agata Wojtkowska, Artur Żbikowski, Roman Lechowski, Katarzyna Zabielska-Koczywąs
The chick embryo chorioallantoic membrane (CAM) model is extensively used in human medicine in preclinical oncological studies. The CAM model has several advantages: low cost, simple experimental approach, time saving and following "3R principles". Research has shown that the human osteosarcoma cell lines U2OS, MMNG-HOS, and SAOS can form tumors on the CAM. In veterinary medicine, this has been described only for feline fibrosarcomas, feline mammary carcinomas and canine osteosarcomas. However, in case of canine osteosarcomas, it has been shown that only non-adherent osteosarcoma stem cells isolated from KTOSA5 and CSKOS cell lines have the ability to form microtumors on the CAM after an incubation period of 5 days, in contrast to adherent KTOSA5 and CSKOS cells...
May 12, 2017: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/28491442/respiratory-distress-associated-with-lungworm-infection-in-a-kitten
#20
Melissa M Hawley, Lynelle R Johnson, Donato Traversa, Dan Bucy, Karen M Vernau, William Vernau
CASE SUMMARY: A 5-month-old feral kitten developed worsening respiratory signs, including tachypnea, coughing and wheezing after standard anthelmintic treatment with fenbendazole at a local shelter. The kitten was referred to the University of California, Davis, William R Pritchard Veterinary Medicine Teaching Hospital for further evaluation. Thoracic radiographs revealed a severe diffuse bronchointerstitial pattern with bronchial cuffing, ill-defined nodules and lymphadenomegaly. Differentials included infectious etiologies such as toxoplasmosis, feline infectious peritonitis and cryptococcosis...
July 2016: JFMS open reports
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