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Feline medicine

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https://www.readbyqxmd.com/read/29780608/bronchoscopic-debulking-of-a-feline-tracheobronchial-carcinoma-and-long-term-outcome
#1
Marina Dominguez Ruiz, Jessica Grant, Juan Hernandez
Case summary: This report describes a 10-year-old female spayed Russian Blue cat presented with a 5 month history of respiratory difficulty. Thoracic radiographs were suggestive of a central airway obstruction. Bronchoscopy revealed a broad-base mass in the region of the carina. Bronchoscopic debulking was performed using a urinary catheter. Histopathology confirmed the presence of a tracheobronchial carcinoma. Survival from diagnosis was 16 months (480 days), over which time the cat underwent three endoscopic debulking procedures in combination with doxorubicin chemotherapy...
January 2018: JFMS open reports
https://www.readbyqxmd.com/read/29776613/high-resolution-melting-analysis-hrm-for-the-assessment-of-clonality-in-feline-b-cell-lymphomas
#2
Manfred Henrich, Svenja Scheffold, Werner Hecht, Manfred Reinacher
Analysis of clonality is gaining importance in diagnosing lymphomas in veterinary medicine. Usually, PCR for the analysis of antigen receptor rearrangement (PARR) is followed by electrophoretic separation of the PCR products. Aim of this study was to test the feasibility of HRM for the assessment of clonality in B-cell lymphomas of cats. High resolution melting analysis differentiates PCR products by their different melting point using the decrease in fluorescence of an intercalating dye during melting of the PCR product...
June 2018: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/29767451/feline-ureteral-obstructions-part-1-medical-management
#3
REVIEW
D L Clarke
Feline ureteral obstructions are an increasingly recognised and challenging diagnostic and management problem. Many cats with ureteral obstructions are critically ill at the time of diagnosis, especially if there is dysfunction of the contralateral kidney. They may present with varying severities of acute kidney injury, electrolyte disturbances, and may have comorbidities such as heart disease that complicate perioperative and long-term management. Medical management, which may consist of rehydration and restoration of intravascular volume with intravenous fluid therapy, osmotic diuresis, ureteral muscle relaxation, and antimicrobials for infection, is important in feline ureteral obstruction patients...
May 16, 2018: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/29757669/historical-prevalence-of-radiological-appendicular-osteoarthritis-in-cats-1972-1973
#4
David Godfrey, Leslie Vaughan
Interest in feline osteoarthritis has grown recently; this might be due to increased prevalence or increased awareness. This study records the presence of appendicular osteoarthritis in a subset of the United Kingdom cat population in the 1970s and estimates its prevalence. One hundred cats euthanized in 1972-1973 had a series of skeletal radiographic images taken post mortem. Each joint was put into a set with or without osteoarthritis according to the presence or absence of a specified set of radiographic features...
May 14, 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29729717/immunohistochemical-characterization-of-immune-cell-infiltration-in-feline-glioma
#5
D R Rissi, B F Porter, C E Boudreau, P M Krimer, A D Miller
The relationship between inflammatory cells and tumour biology has been defined in many human intracranial neoplasms, but it is relatively poorly characterized in veterinary medicine. The aim of this study was to define the immune cell infiltration in cases of feline glioma and its possible association with tumour morphology and type. A retrospective search identified 18 gliomas that met inclusion criteria. Tumours were subjected to immunohistochemistry (IHC) for CD3, CD20, Iba1, MAC387 and factor VIII-related antigen...
April 2018: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/29713639/from-feline-idiopathic-ulcerative-dermatitis-to-feline-behavioral-ulcerative-dermatitis-grooming-repetitive-behaviors-indicators-of-poor-welfare-in-cats
#6
Emmanuelle Titeux, Caroline Gilbert, Amaury Briand, Noëlle Cochet-Faivre
Feline idiopathic head-and-neck dermatitis-also named feline idiopathic ulcerative dermatitis (IUD)-is considered as a rare skin disease of unknown origin. It is usually associated with a crusted, non-healing, self-induced ulcer occurring most commonly on the dorsal or lateral neck or between the scapula where self-grooming by scratching occurs. Usually, IUD is diagnosed after exclusion of other causes of pruritus. In feline medicine, self-induced alopecia is recognized as a behavioral disorder (abnormal repetitive behavior) due to excessive licking, which is an amplification of a normal maintenance behavior...
2018: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29706095/understanding-feline-emotions-%C3%A2-and-their-role-in-problem-behaviours
#7
Sarah Heath
Practical relevance: Despite its importance, emotional health is a subject that is sadly neglected in the context of companion animals. Understanding emotions is at the heart of veterinary behavioural medicine and is key to preventing, managing and treating reported behavioural problems in domestic cats. Clinical challenges: On a daily basis, veterinary practices are presented with the physical health impact of emotional health and with emotionally motivated behaviours that are undesirable to owners and/or detrimental to the cat...
May 2018: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29706092/normal-feline-behaviour-%C3%A2-and-why-problem-behaviours-develop
#8
John Bradshaw
Practical relevance: Cats are descended from a solitary, territorial ancestor, and while domestication has reduced their inherited tendency to be antagonistic towards all animals larger than their typical prey, they still place more reliance on the security of their territory than on psychological attachments to people or other cats, the exact opposite to dogs. Many feline problem behaviours stem from perceived threats to this security, often due to conflicts with other cats. Others are more developmental in origin, often caused by inadequate exposure to crucial stimuli, especially people, during the socialisation period...
May 2018: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29623690/observation-about-phosphorus-and-protein-supply-in-cats-and-dogs-prior-to-the-diagnosis-of-chronic-kidney-disease
#9
L F Böswald, E Kienzle, B Dobenecker
There is evidence that nutritional phosphorus (P) excess may be a risk factor for chronic kidney disease (CKD) in humans and pets (Advances in Nutrition: An International Review Journal (2014), 5, 104; The American Journal of Clinical Nutrition, (2013), 98, 6; Journal of Feline Medicine and Surgery, (2017); The source of phosphorus influences serum PTH, apparent digestibility and blood levels of calcium and phosphorus in dogs fed high phosphorus diets with balanced Ca/P ratio. Proc. Waltham International Nutritional Sciences Symposium, USA; Clinical aspects of natural and added phosphorus in foods, 2017, Springer Science+Business, Media)...
April 2018: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29572939/computed-tomographic-appearance-of-abdominal-lymph-nodes-in-healthy-cats
#10
Michael Perlini, Andrew Bugbee, Scott Secrest
BACKGROUND: Computed tomography (CT) is commonly used in veterinary medicine and plays an important role in disease identification and cancer staging. Identification of abnormal abdominal lymph nodes is important for clinical, therapeutic, and prognostic decision making. No published study describes the CT appearance of abdominal lymph nodes in healthy cats. HYPOTHESIS/OBJECTIVES: All abdominal lymph centers will be identified on CT with the majority of lymph nodes being elongated and homogenously contrast enhancing...
March 23, 2018: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29552354/juvenile-hyposomatotropism-in-a-somali-cat-presenting-with-seizures-due-to-intermittent-hypoglycaemia
#11
Maya Laura König, Diana Henke, Katja Adamik, Cristina Pérez Vera
Case summary: A 3-month-old intact male Somali cat was evaluated for a history of seizures, hypoglycaemia and mental dullness 4 weeks after being bitten in the head by a dog. The cat's body size and weight were approximately half that of his littermates and its haircoat was woolly, with fewer guard hairs. Multiple hypoglycaemic episodes were documented over a period of 4 weeks, which resolved rapidly after correction of the hypoglycaemia. Juvenile hyposomatotropism was presumptively diagnosed by demonstrating low circulating levels of insulin-like growth factor 1 and after exclusion of other endocrine and non-endocrine causes of small stature and hypoglycaemia...
January 2018: JFMS Open Reports
https://www.readbyqxmd.com/read/29529957/circulating-cell-free-dna-does-not-harbour-a-diagnostic-benefit-in-cats-with-feline-diffuse-iris-melanomas
#12
Jessica G Rushton, Reinhard Ertl, Dieter Klein, Alexander Tichy, Barbara Nell
Objectives Feline diffuse iris melanoma (FDIM) is the most common malignant primary intraocular tumour in cats, with reported metastases rates between 19% and 63%. Currently, the only available diagnostic tool for a tentative diagnosis is histopathological examination of the enucleated eye. Therefore, the veterinary ophthalmologist is often faced with the dilemma of whether to enucleate an oftentimes visual eye or to continue monitoring, with the risk of metastases developing. In the past, cell-free DNA (cfDNA) gained more attention in human medicine, especially in the field of oncology...
March 1, 2018: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29486883/photodynamic-therapy-and-diagnosis-principles-and-comparative-aspects
#13
REVIEW
Jane Dobson, Genilson Fernandes de Queiroz, Jon P Golding
Photodynamic therapy (PDT) is an evolving method of treating superficial tumours that is non-invasive and carries minimal risk of toxicity. It combines tumour-selective photosensitiser dyes, tissue oxygen and targeted illumination to generate cytotoxic reactive oxygen species (ROS) within the tumour. In addition to directly acting on tumour cells, PDT damages and restricts tumour microvasculature, and causes a local inflammatory response that stimulates an immune response against the tumour. Unlike surgery or radiotherapy, the surrounding extracellular matrix is unaffected by PDT; thus, tissue healing is excellent and PDT seldom causes scars...
March 2018: Veterinary Journal
https://www.readbyqxmd.com/read/29478398/mesenchymal-stem-cell-therapy-in-cats-current-knowledge-and-future-potential
#14
Jessica M Quimby, Dori L Borjesson
Practical relevance: Stem cell therapy is an innovative field of scientific investigation with tremendous potential for clinical application in veterinary medicine. Based on the known desirable immunomodulatory properties of mesenchymal stem cells, this therapy holds promise for the treatment of a variety of inflammatory diseases in cats. AIMS: This review details our current understanding of feline stem cell biology and proposed mechanism of action. Studies performed in feline clinical trials for diseases including gingivostomatitis, chronic enteropathy, asthma and kidney disease are summarized, with the goal of providing an overview of the current status of this treatment modality and its potential for the future...
March 2018: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29408407/antimicrobial-susceptibility-survey-on-bacterial-agents-of-canine-and-feline-urinary-tract-infections-weight-of-the-empirical-treatment
#15
Elisa Rampacci, Marco Bottinelli, Valentina Stefanetti, Doreene R Hyatt, Elisa Sgariglia, Mauro Coletti, Fabrizio Passamonti
OBJECTIVES: This work characterizes the antimicrobial susceptibility of uropathogens isolated from empirically treated dogs and cats. Within-household transmission of uropathogens can involve humans and companion animals. Knowledge on the prevalence and susceptibility pattern of isolates from canine and feline urine samples and the impact of prior antimicrobial treatment is important to prevent the dissemination of antimicrobial resistance. METHODS: A retrospective study was conducted selecting antibiotically treated companion animals...
February 3, 2018: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/29405805/comparison-of-predicted-intrinsic-hepatic-clearance-of-30-pharmaceuticals-in-canine-and-feline-liver-microsomes
#16
Marike Visser, Matthew J Zaya, Charles W Locuson, Dawn M Boothe, Dawn A Merritt
1. Known cytochrome P450 (CYP) substrates in humans are used in veterinary medicine, with limited knowledge of the similarity or variation in CYP metabolism. Comparison of canine and feline CYP metabolism via liver microsomes report that human CYP probes and inhibitors demonstrate differing rates of intrinsic clearance (CLint ). 2. The purpose of this study was to utilize a high-throughput liver microsome substrate depletion assay, combined with microsomal and plasma protein binding to compare the predicted hepatic clearance (CLhep ) of thirty therapeutic agents used off-label in canines and felines, using both the well-stirred and parallel tube models...
March 6, 2018: Xenobiotica; the Fate of Foreign Compounds in Biological Systems
https://www.readbyqxmd.com/read/29398100/vertical-or-horizontal-diagnosing-and-treating-cats-who-urinate-outside-the-box
#17
REVIEW
Leticia Mattos de Souza Dantas
Feline elimination problems are commonly presented to general practitioners and behavioral medicine specialists. The correct diagnosis is often missed by veterinarians owing to individual variation and multifactorial cases. Three diagnostic umbrellas need to be considered: medical problems, toileting behavior outside of the litter box, and urine marking. The treatment plan for most cases, regardless of etiology, involves optimum litter box management, fulfilling cats' environmental needs, stress reduction, behavior therapy techniques, and trigger removal...
May 2018: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/29393763/conversation-analysis-of-veterinarians-proposals-for-long-term-dietary-change-in-companion-animal-practice-in-ontario-canada
#18
Clare MacMartin, Hannah C Wheat, Jason B Coe, Cindy L Adams
Nutritional changes recommended by veterinarians to clients can have a major role in animal-patient health. Although there is literature on best practices that can inform veterinary communication training, little is known specifically about how veterinarians communicate their recommendations to clients in real-life interactions. This study used the qualitative research method of conversation analysis to investigate the form and content of veterinarian-initiated proposals for long-term dietary change in canine and feline patients to further inform veterinary communication training...
February 2, 2018: Journal of Veterinary Medical Education
https://www.readbyqxmd.com/read/29374128/young-scientist-award-in-feline-medicine
#19
LETTER
Karin de Lange
No abstract text is available yet for this article.
January 27, 2018: Veterinary Record
https://www.readbyqxmd.com/read/29353423/polymerase-chain-reaction-based-detection-of-myc-transduction-in-feline-leukemia-virus-infected-cats
#20
Ryosuke Sumi, Ariko Miyake, Taiji Endo, Yoshiharu Ohsato, Minh Ha Ngo, Kazuo Nishigaki
Feline lymphomas are associated with the transduction and activation of cellular proto-oncogenes, such as c-myc, by feline leukemia virus (FeLV). We describe a polymerase chain reaction assay for detection of myc transduction usable in clinical diagnosis. The assay targets c-myc exons 2 and 3, which together result in a FeLV-specific fusion gene following c-myc transduction. When this assay was conducted on FeLV-infected feline tissues submitted for clinical diagnosis of tumors, myc transduction was detected in 14% of T-cell lymphoma/leukemias...
April 2018: Archives of Virology
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