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https://www.readbyqxmd.com/read/27908491/clinical-outcomes-of-botox-injections-for-chronic-temporomandibular-disorders-do-we-understand-how-botox-works-on-muscle-pain-and-the-brain
#1
S T Connelly, J Myung, R Gupta, G M Tartaglia, A Gizdulich, J Yang, R Silva
The main objective of this retrospective review was to analyze the clinical outcomes following the use of botulinum toxin (onabotulinumtoxinA, Botox) injections to relieve the symptoms of chronic temporomandibular disorders (TMD). Seventy-one patients with a diagnosis of TMD (according to the RDC/TMD international consortium) associated with or without bruxism and refractory to conventional treatment (e.g. oral appliances, physiotherapy, etc.) received Botox injections into the temporalis and masseter muscles...
November 28, 2016: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27907894/interventions-for-orthodontically-induced-white-spot-lesions-a-systematic-review-and-meta-analysis
#2
REVIEW
Damian Höchli, Monika Hersberger-Zurfluh, Spyridon N Papageorgiou, Theodore Eliades
BACKGROUND: Although orthodontic white spot lesions (WSLs) are one of the most often and most evident adverse effects of comprehensive fixed appliance treatment, the efficacy of interventions for WSLs has not yet been adequately assessed in an evidence-based manner. OBJECTIVE: Aim of this systematic review was to assess the therapeutic and adverse effects of interventions to treat post-orthodontic WSLs from randomized trials in human patients. SEARCH METHODS: An unrestricted electronic search of eight databases from inception to May 2016...
October 17, 2016: European Journal of Orthodontics
https://www.readbyqxmd.com/read/27891568/oral-hygiene-compliance-in-orthodontic-patients-a-randomized-controlled-study-on-the-effects-of-a-post-treatment-communication
#3
Mauro Cozzani, Giulia Ragazzini, Alessia Delucchi, Sabrina Mutinelli, Carlo Barreca, Daniel J Rinchuse, Roberto Servetto, Vincenzo Piras
BACKGROUND: Several studies have recently demonstrated that a post-treatment communication to explain the importance of an oral hygiene can improve the orthodontic patients' compliance over a period of 66 days. The main goal of this study is to evaluate the effects of a structured follow-up communication after orthodontic appliance application on oral hygiene compliance after 30-40 days. METHODS: Eighty-four orthodontic participants enrolled from patients who were beginning fixed orthodontic treatment at the Orthodontic Department, Gaslini Hospital, Genova, between July and October 2014 were randomly assigned to one of three trial arms...
December 2016: Progress in Orthodontics
https://www.readbyqxmd.com/read/27884081/a-randomized-cross-over-study-comparing-the-efficacy-of-two-mandibular-advancement-appliances-in-the-treatment-of-mild-moderate-obstructive-sleep-apnea
#4
Ayman Al-Dharrab
OBJECTIVE: To compare efficacy, side effects, patient compliance, and preference between two types of custom-made mandibular advancement appliances (MAAs) in the treatment of patients with mild to moderate obstructive sleep apnea (OSA). METHODOLOGY: This prospective, randomized, crossover study of 12 patients with mild to moderate OSA compared a titratable and a non-titratable MAA. Each patient was fitted with both appliances in a random order with a washout period of two weeks...
November 24, 2016: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/27871960/useful-implications-of-low-dose-long-term-use-of-pde-5-inhibitors
#5
REVIEW
Taymour Mostafa
INTRODUCTION: Phosphodiesterase type 5 (PDE-5) hydrolyzes cyclic guanylate monophosphate (cGMP) specifically to 5' GMP, promoting successful corporeal vascular relaxation and penile erection during sexual stimulation. Oral PDE-5 inhibitors such as sildenafil, vardenafil, tadalafil, and avanafil have provided noninvasive, effective, well-tolerated treatment for erectile dysfunction (ED) patients and, at the same time, stimulated both academic and clinical interests. Lately, some oral PDE-5 inhibitors were released as low-dose preparations with the concept of potential daily administration and long-term use...
July 2016: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/27871708/treatment-associated-changes-in-malocclusion-and-oral-health-related-quality-of-life-a-4-year-cohort-study
#6
David L Healey, Robin D C Gauld, W Murray Thomson
INTRODUCTION: The impact of orthodontic treatment on oral health-related quality of life (OHRQoL) in adolescents being treated in orthodontic practices has not yet been explored longitudinally. The aim of this cohort study was to describe the changes in both malocclusion and OHRQoL with orthodontic treatment. METHODS: One hundred seventy-four patients (ages, 10-17 years; 64.4% girls; 81.6% European) underwent 2-arch, fixed-appliance treatment in a 4-year prospective study conducted across 19 specialist orthodontic practices throughout New Zealand...
November 2016: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/27870138/promise-of-combining-antifungal-agents-in-denture-adhesives-to-fight-candida-species-infections
#7
Jorge L Garaicoa, Carol L Fischer, Amber M Bates, Julie Holloway, Gustavo Avila-Ortiz, Janet M Guthmiller, Georgia K Johnson, Clark Stanford, Kim A Brogden
PURPOSE: Several complications may arise in patients wearing complete prosthetic appliances, including denture-associated infections and mucosal stomatitis due to Candida species. This study evaluated the activity of anti-Candida agents in denture adhesive and the cytotoxicities of these preparations for primary human gingival epithelial (GE) keratinocytes. MATERIALS AND METHODS: The anti-Candida activities of antimicrobial peptides, antimicrobial lipids, and antifungal agents against C...
November 21, 2016: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/27864320/three-questionnaires-to-assess-the-perception-of-fixed-orthodontic-therapy-before-during-and-after-treatment-validity-and-reliability
#8
Yassir A Yassir, Grant T McIntyre, David R Bearn
BACKGROUND/OBJECTIVE: To assess the validity and reliability of a series of three questionnaires for the quantification of patient perception of fixed appliance orthodontic treatment. SUBJECTS AND METHODS: The study was carried out at the University of Dundee with content and face validity being assessed using proformas. Initially ten experts (Orthodontic Specialists) assessed content validity with 11 professionals (seven Orthodontic Specialists and four Postgraduates) and 20 patients assessing face validity...
November 17, 2016: European Journal of Orthodontics
https://www.readbyqxmd.com/read/27826882/mandibular-advancement-appliance-for-obstructive-sleep-apnea-treatment
#9
J Kostrzewa-Janicka, P Śliwiński, M Wojda, D Rolski, E Mierzwińska-Nastalska
A combination of abnormal anatomy and physiology of the upper airway can produce its repetitive narrowing during sleep, resulting in obstructive sleep apnea (OSA). Treatment of sleep-breathing disorder ranges from lifestyle modifications, upper airway surgery, continuous positive airway pressure (CPAP) to the use of oral appliances. A proper treatment selection should be preceded by thorough clinical and instrumental examinations. The type and number of specific oral appliances are still growing. The mandibular advancement appliance (MAA) is the most common type of a dental device in use today...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27811470/remineralizing-potential-of-a-low-fluoride-toothpaste-with-sodium-trimetaphosphate-an-in-situ-study
#10
Eliana M Takeshita, Marcelle Danelon, Luciene P Castro, Robson F Cunha, Alberto C B Delbem
OBJECTIVE: To evaluate the effect of a low-fluoride (F) toothpaste supplemented with sodium trimetaphosphate (TMP) on enamel remineralization in situ. DESIGN: Bovine enamel blocks were selected on the basis of their surface hardness (SH) after caries-like lesions had been induced, and randomly divided into 4 treatment groups, according to the toothpastes used: without F or TMP (placebo); 500 ppm F; 500 ppm F plus 1% TMP; and 1,100 ppm F. The study design was blinded and crossover and performed in 4 phases of 3 days each...
November 4, 2016: Caries Research
https://www.readbyqxmd.com/read/27810015/pediatric-obstructive-sleep-apnea
#11
REVIEW
Zarmina Ehsan, Stacey L Ishman
Screening for obstructive sleep apnea (OSA) with in-laboratory polysomnography is recommended for children with sleep disordered breathing. Adenotonsillectomy is the first-line therapy for pediatric OSA, although intranasal steroids and montelukast can be considered for those with mild OSA and continuous positive airway pressure for those with moderate to severe OSA awaiting surgery, poor surgical candidates or persistent OSA. Bony or soft tissue upper airway surgery is reasonable for children failing medical management or those with persistent OSA following adenotonsillectomy...
December 2016: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/27797160/pathogenesis-of-central-and-complex-sleep-apnoea
#12
REVIEW
Jeremy E Orr, Atul Malhotra, Scott A Sands
Central sleep apnoea (CSA) - the temporary absence or diminution of ventilatory effort during sleep - is seen in a variety of forms including periodic breathing in infancy and healthy adults at altitude and Cheyne-Stokes respiration in heart failure. In most circumstances, the cyclic absence of effort is paradoxically a consequence of hypersensitive ventilatory chemoreflex responses to oppose changes in airflow, that is elevated loop gain, leading to overshoot/undershoot ventilatory oscillations. Considerable evidence illustrates overlap between CSA and obstructive sleep apnoea (OSA), including elevated loop gain in patients with OSA and the presence of pharyngeal narrowing during central apnoeas...
October 31, 2016: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/27793169/oral-microbiota-carriage-in-patients-with-multibracket-appliance-in-relation-to-the-quality-of-oral-hygiene
#13
Katharina Klaus, Johanna Eichenauer, Rhea Sprenger, Sabine Ruf
BACKGROUND: The present study aimed to investigate the prevalence of oral microbiota (Candida species (spp.), Streptococcus mutans, and Lactobacilli) in patients with multibracket (MB) appliances in relation to the quality of oral hygiene. Saliva and plaque samples were collected from three groups of 25 patients each (good oral hygiene (GOH), poor oral hygiene (POH), and poor oral hygiene with white spot lesions (POH/WSL)). Counts of colony forming units (CFU) of the investigated oral microbiota were compared using Chi-square and Mann-Whitney U tests...
October 28, 2016: Head & Face Medicine
https://www.readbyqxmd.com/read/27793138/consequences-of-orthodontic-treatment-in-malocclusion-patients-clinical-and-microbial-effects-in-adults-and-children
#14
Li Guo, Ying Feng, Hong-Gang Guo, Bo-Wen Liu, Yang Zhang
BACKGROUND: Malocclusion is a common disease of oral and maxillofacial region. The study was aimed to investigate levels changes of periodontal pathogens in malocclusion patients before, during and after orthodontic treatments, and to confirm the difference between adults and children. METHOD: One hundred and eight malocclusion patients (46 adults and 62 children at the school-age) were randomly selected and received orthodontic treatment with fixed orthodontic appliances...
October 28, 2016: BMC Oral Health
https://www.readbyqxmd.com/read/27792427/changes-in-salivary-periodontal-pathogens-after-orthodontic-treatment-an-in-vivo-prospective-study
#15
Kyungsun Kim, Woo-Sun Jung, Soha Cho, Sug-Joon Ahn
OBJECTIVE:   To analyze the initial changes in salivary levels of periodontal pathogens after orthodontic treatment with fixed appliances. MATERIALS AND METHODS:   The subjects consisted of 54 adult patients. The Simplified Oral Hygiene Index, Plaque Index, and Gingival Index were measured as periodontal parameters. Both the plaque and gingival indexes were obtained from the central and lateral incisors and first molars of both arches. Whole saliva and periodontal parameters were obtained at the following four time points: immediately before debonding (T1), 1 week after debonding (T2), 5 weeks after debonding (T3), and 13 weeks after debonding (T4)...
November 2016: Angle Orthodontist
https://www.readbyqxmd.com/read/27779317/adhesives-for-fixed-orthodontic-bands
#16
REVIEW
Declan T Millett, Anne-Marie Glenny, Rye Cr Mattick, Joy Hickman, Nicky A Mandall
BACKGROUND: Orthodontic treatment involves using fixed or removable appliances (dental braces) to correct the positions of teeth. It has been shown that the quality of treatment result obtained with fixed appliances is much better than with removable appliances. Fixed appliances are, therefore, favoured by most orthodontists for treatment. The success of a fixed orthodontic appliance depends on the metal attachments (brackets and bands) being attached securely to the teeth so that they do not become loose during treatment...
October 25, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27759405/association-between-clinical-and-salivary-microbial-parameters-during-orthodontic-treatment-with-removable-appliances-with-or-without-use-of-fluoride-mouth-rinse
#17
Z Zingler, M Pritsch, C J Lux, S Kneist
AIM: To evaluate the correlation between clinical and salivary microbial parameters during treatment with removable orthodontic appliances with or without use of fluoride mouth rinse. MATERIALS AND METHODS: A group of 48 patients completed this randomized, controlled, parallel-group, clinical pilot study. 24 patients of the test group (TG) rinsed after tooth brushing with a fluoride mouth rinse (100 ppm AmF/150 ppm NaF) while 21 patients of the control group (CG) did not...
September 2016: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/27751674/perceived-effectiveness-self-efficacy-and-social-support-for-oral-appliance-therapy-among-older-veterans-with-obstructive-sleep-apnea
#18
Nancy J Carballo, Cathy A Alessi, Jennifer L Martin, Michael N Mitchell, Ron D Hays, Nananda Col, Emily S Patterson, Stella Jouldjian, Karen Josephson, Constance H Fung
PURPOSE: Obstructive sleep apnea is a prevalent sleep disorder among older adults. Oral appliances are increasingly prescribed as therapy for obstructive sleep apnea. Adherence to oral appliance therapy is highly variable. Based on value-expectancy theory and other social-psychological theories, adherence to oral appliance therapy may be influenced by patients' perceived effectiveness of the therapy, self-efficacy, and availability of social support. We examined these perceptions among older adults with obstructive sleep apnea who were prescribed oral appliance therapy...
November 2016: Clinical Therapeutics
https://www.readbyqxmd.com/read/27734089/efficacy-of-a-new-sealant-to-prevent-white-spot-lesions-during-fixed-orthodontic-treatment-a-12-month-single-center-randomized-controlled-clinical-trial
#19
Shaza M Hammad, Michael Knösel
BACKGROUND AND OBJECTIVE: White spot lesions (WSLs) are an undesirable side effect of fixed orthodontic appliance therapy and are reported to occur in 2-96 % of orthodontic patients. In this study, the efficacy of a new sealant to prevent WSLs during fixed orthodontic treatment was compared to a control group that did not receive sealant. PATIENTS AND METHODS: For this 2-arm parallel-group randomized trial, 50 subjects aged 12-18 years (mean age 14.57 ± 2...
October 12, 2016: Journal of Orofacial Orthopedics, Fortschritte der Kieferorthopädie
https://www.readbyqxmd.com/read/27720461/oral-appliances-in-obstructive-sleep-apnea
#20
Anthony Dioguardi, Moh'd Al-Halawani
Oral appliance therapy (OAT) has become an increasingly popular nonsurgical option for the treatment of obstructive sleep disorders. Recent research supports its efficacy and high levels of compliance for patients with obstructive sleep disorders. Common side effects of OAT include temporomandibular joint-related symptoms, bite changes, and tooth movement. These side effects can be minimized by the use of exercises. The American Academy of Dental Sleep Medicine and the American Academy of Sleep Medicine have released joint clinical practice guidelines for the treatment of obstructive sleep apnea and snoring with OAT...
October 6, 2016: Otolaryngologic Clinics of North America
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