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Michael C Grant, Matthew Betz, Matthew Hulse, Andres Zorrilla-Vaca, Deborah Hobson, Elizabeth Wick, Christopher L Wu
BACKGROUND: Nonopioid adjuvant medications are increasingly included among perioperative Enhanced Recovery After Surgery protocols. Preoperative pregabalin has been shown to improve postoperative pain and limit reliance on opioid analgesia. Our group investigated the ability of preoperative pregabalin to also prevent postoperative nausea and vomiting (PONV). METHODS: Our group performed a meta-analysis of randomized trials that report outcomes on the effect of preoperative pregabalin on PONV endpoints in patients undergoing general anesthesia...
July 26, 2016: Anesthesia and Analgesia
Daisy Krakowiak, John Kinuthia, Alfred O Osoti, Victor Asila, Molly A Gone, Jennifer Mark, Bourke Betz, Saloni Parikh, Monisha Sharma, Ruanne Barnabas, Carey Farquhar
INTRODUCTION: Male partner HIV testing has been recognized as an important component of prevention of mother-to-child HIV transmission. Scheduled home-based couple HIV testing may be an effective strategy to reach men. METHODS: Women attending their first antenatal visit at Kisumu County Hospital in Kenya were randomized to home-based education and HIV testing within 2 weeks of enrollment (HOPE) or to written invitations for male partners to attend clinic (INVITE)...
August 1, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
M Bickel, W Marben, C Betz, P Khaykin, C Stephan, P Gute, A Haberl, G Knecht, T Wolf, H R Brodt, H Geiger, E Herrmann, O Jung
OBJECTIVES: Renal disease is a common and serious complication in HIV-infected patients. METHODS: A retrospective cohort analysis for the period 1989-2010 was carried out to determine the prevalence, incidence and risk factors for end-stage renal disease (ESRD). ESRD was defined as initiation of renal replacement therapy. Three time periods were defined: 1989-1996 [pre-highly active antiretroviral therapy (HAART)], 1997-2003 (early HAART) and 2004-2010 (late HAART)...
March 2013: HIV Medicine
R Fischer-Betz, M Halle, M Schneider
Rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are associated with increased mortality, largely as a consequence of cardiovascular (CV) disease. Studies found relative risk ratios of 2 for myocardial infarction in RA and up to 7 for myocardial infarction in SLE patients.Beyond the traditional CV risk factors, chronic systemic inflammation has been shown to be a crucial factor in atherosclerosis development and progression from endothelial dysfunction to plaque rupture and thrombosis. Numerous studies have shown that atherosclerosis is not a passive process characterized by accumulation of lipids in the vessel walls, but rather represents active inflammation of the vasculature...
October 2010: Zeitschrift Für Rheumatologie
R Fischer-Betz, S Beer, M Schneider
Large increases in mortality related to premature atherosclerosis with coronary artery disease and stroke have been reported during the last few years in patients with systemic lupus erythematosus (SLE). Studies found relative risks of 5 to 7 for myocardial infarction in SLE patients. The traditional risk factors fail to fully account for accelerated atherosclerosis in SLE and APS, in addition prolonged glucocorticoid therapy and long duration of SLE seem to be of importance. The disease SLE per se is an independent risk factor...
May 2005: Zeitschrift Für Rheumatologie
Hans-Peter Bestehorn, Franz-Josef Neumann, Heinz Joachim Büttner, Peter Betz, Peter Stürzenhofecker, Eberhard von Hodenberg, Antoine Verdun, Laszlo Levai, Jean Pierre Monassier, Helmut Roskamm
OBJECTIVES: We investigated the effect of oral verapamil on clinical outcome and angiographic restenosis after percutaneous coronary intervention (PCI). BACKGROUND: Thus far, there is no established systemic pharmacologic approach for the prevention of restenosis after PCIs. Five small studies reported encouraging results for calcium channel blockers. METHODS: Our randomized double-blind trial included 700 consecutive patients with successful PCI of a native coronary artery...
June 16, 2004: Journal of the American College of Cardiology
A M Morin, O Betz, P Kranke, G Geldner, H Wulf, L H Eberhart
OBJECTIVE: Ginger (Zingiber officinale) has traditionally been used in China for gastrointestinal symptoms, including nausea and vomiting. A recent systematic review on the possible antiemetic effect of ginger for various indications, including PONV, morning sickness, and motion sickness, concluded that ginger was a promising antiemetic herbal remedy, but the clinical data were insufficient to draw firm conclusions. Since that publication, additional data has accumulated and thus an updated meta-analysis was performed...
May 2004: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
C Fabbriciani, A S Panni, A Delcogliano
The results of 50 arthroscopic lateral releases are reported. The average follow-up period was 36 months with a range of 18-52 months. Satisfactory results were achieved in 71% of 21 patients with patellar pain alone and in 76% of those (Betz RR, Lonergan R, Patterson R. The percutaneous lateral retinacular release Orthopaedics 1982;5:57-62) with instability. Patients with patellofemoral osteoarthritis or patellar dislocation were excluded from the series. Postoperative hemarthrosis occurred in 10%. Unsatisfactory results could be related to incomplete release, severe chondromalacia, or insufficient rehabilitation...
1992: Arthroscopy: the Journal of Arthroscopic & related Surgery
K Meyer, A Kardos, L Samek, M Lehmann, K Kurz, U Caspar, C Droste, P Betz, H Weidemann, H Roskamm
UNLABELLED: In the rehabilitation of coronary patients there is an increased interest in using complementary resistance exercise training. Therefore, we studied nine patients (males; age: 51 +/- 7 years) with chronic stable coronary heart disease during extensive resistance exercise (ex RE) (legpress, abduction, adduction) (60-s work: 60-s rest; contraction intensity: 65% of 1 RM) and during intensive resistance exercise (int. RE) (legpress) (30-s work: 45-s rest) with 85% of 1 RM. Non-invasive continuously measured blood pressure, heart rate, norepinephrine, epinephrine, lactic acid, and glucose were compared with values from maximal bicycle ergometry (3-min steps, each 25 w; max...
October 1992: Zeitschrift Für Kardiologie
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