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https://www.readbyqxmd.com/read/28814061/modular-one-to-many-clutchable-actuator-for-a-soft-elbow-exosuit
#1
M Canesi, M Xiloyannis, A Ajoudani, A Biechi, L Masia
Exoskeletons have been developed for a wide range of applications, from the military to the medical field, with the aim of augmenting human performance or compensating for neuromuscular deficiencies. However, to empower the high number of degrees of freedom of the human body, they often employ a high number of motors, increasing the size, weight and power consumption of the system. We hereby present an actuation strategy to empower our elbow exosuit that adopts a single motor to drive multiple, independently actuated, degrees of freedom...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813740/west-nile-review-15-years-of-human-disease-in-south-dakota-2002-2016
#2
Lon Kightlinger
During the past 15 years, 2002-2016, West Nile virus (WNV) has emerged in South Dakota resulting in 509 neuroinvasive disease (NID) cases, 745 hospitalizations and 38 deaths. Culex tarsalis is the state's primary mosquito vector. South Dakota's average annual incidence of WNV-NID and death rate are the highest of any state in the U.S. WNV cases have been reported from all counties in the state. All age groups have been infected with cases peaking in the 40-44 year age group, but deaths peaking in cases 70 years and older...
August 2017: South Dakota Medicine: the Journal of the South Dakota State Medical Association
https://www.readbyqxmd.com/read/28813710/is-endoscopic-vasectomy-just-a-dream-an-ex-vivo-study-on-feasibility-and-reliability-of-endoluminal-occlusion-of-porcine-vas-deferens
#3
Daniel Schlager, Moritz Maas, Simon Hein, Fabian Adams, Martin Schoenthaler, Bjoern Spittau, Ulrich Wetterauer, Arkadiusz Miernik
INTRODUCTION AND AIM: Surgical vasectomy remains the gold standard for fertility control in men. Endoluminal occlusion of the seminal ducts, thus avoiding an external incision, may become an appealing alternative to this approach. As our group has shown, nontraumatic endoscopic inspection of the seminal ducts is feasible in the human cadaver. We investigated the feasibility and reliability of occlusion using several commercially available medical sealing agents in the porcine vas deferens (VD)...
August 17, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28812381/retrospective-review-of-sglt2-inhibitor-exposures-reported-to-13-poison-centers
#4
Scott E Schaeffer, Carol DesLauriers, Henry A Spiller, Alfred Aleguas, Salvador Baeza, Mark L Ryan
BACKGROUND: SGLT2 inhibitors are a new class of oral antidiabetics prescribed in the United States since 2013. They act by inhibiting reabsorption of glucose in the proximal convoluted tubule of the kidney, allowing excess glucose to be excreted. Little has been reported regarding effects of non-therapeutic exposure to this class of medication. METHODS: Retrospective records from 13 poison centers were examined for human exposures to SGLT2 inhibitors between 1st January 2013 and 31st December 2016...
August 16, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28812121/-teaching-in-orthopaedic-and-trauma-surgery
#5
T Renkawitz, A Benditz, M Rüsseler, U Obertacke, J Grifka, M Weber
The scramble for available places to study medicine in Germany continues. One of the core points within the "Master Plan 2020", which has been recently adopted, is the reform of teaching concepts at German medical faculties. In the future, students of human medicine are to be trained primarily based upon competence-oriented, integrated curricula. The present paper is intended to present modern teaching concepts and methods, as well as current examination formats, which play a special role in student training in orthopaedics and traumatology...
August 15, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/28811837/an-interview-with-samuel-shem-author-of-the-house-of-god
#6
Claire Brash
Dr Stephen Bergman, Professor of medical humanities at New York University, writes under the name Samuel Shem. He is an acclaimed author of several novels, plays and textbooks, and his work has been translated into several languages -'The House of God' his first novel has sold over 3 million copies. His work exposes the potential moral challenges of the medical workplace and the connection between values, good relationships and healing. In 2015 he visited the UK for medical humanities academic tour which included keynote talks at the RCGP 2015 Annual Conference and at the Royal Society of Medicine...
July 2017: London Journal of Primary Care
https://www.readbyqxmd.com/read/28811624/pupil-size-tracks-attentional-performance-in-attention-deficit-hyperactivity-disorder
#7
G Wainstein, D Rojas-Líbano, N A Crossley, X Carrasco, F Aboitiz, T Ossandón
Attention-deficit/hyperactivity disorder (ADHD) diagnosis is based on reported symptoms, which carries the potential risk of over- or under-diagnosis. A biological marker that helps to objectively define the disorder, providing information about its pathophysiology, is needed. A promising marker of cognitive states in humans is pupil size, which reflects the activity of an 'arousal' network, related to the norepinephrine system. We monitored pupil size from ADHD and control subjects, during a visuo-spatial working memory task...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28811598/effects-of-contaminants-of-emerging-concern-on-megaselia-scalaris-lowe-diptera-phoridae-and-its-microbial-community
#8
Marcus J Pennington, Jason A Rothman, Michael B Jones, Quinn S McFrederick, Jay Gan, John T Trumble
Drought, rising temperatures, and expanding human populations are increasing water demands. Many countries are extending potable water supplies by irrigating crops with wastewater. Unfortunately, wastewater contains biologically active, long-lived pharmaceuticals, even after treatment. Run-off from farms and wastewater treatment plant overflows contribute high concentrations of pharmaceuticals to the environment. This study assessed the effects of common pharmaceuticals on a cosmopolitan saprophagous insect, Megaselia scalaris (Diptera: Phoridae)...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28810998/delayed-diagnosis-of-acromegaly-in-the-context-of-post-traumatic-stress-disorder-due-to-symptoms-mimicking-known-psychotropic-medication-side-effects
#9
Ray-Bernard Portier, Afshin Afarin, Sara Pope
BACKGROUND: Acromegaly is caused by elevated secretion of human growth hormone, which is frequently because of intracranial tumors. This diagnosis is fairly uncommon with an incidence of 3 to 4 cases per million patients per year. We are presenting a case of acromegaly diagnosed in an active duty Chief Petty Officer. MATERIALS AND METHODS: A 38-year-old male Chief Petty Officer with no previous mental health diagnosis experienced post-traumatic stress disorder (PTSD)-like symptoms in early 2012 after deploying to Iraq and Afghanistan from 2010 to 2011...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28810978/factors-associated-with-medical-school-entrants-interest-in-military-financial-assistance-in-exchange-for-a-service-obligation-the-michigan-state-university-college-of-human-medicine-cohort
#10
Dean G Sienko, Kathleen Oberst
INTRODUCTION: The U.S. military offers comprehensive scholarships to medical students to help offset costs in exchange for either reserve or active duty service commitments. Our goal was to describe to what degree newly admitted students to Michigan State University's College of Human Medicine were aware of and interested in these opportunities. MATERIALS AND METHODS: We surveyed 176 newly admitted students at the beginning and immediately following a presentation on military medicine opportunities...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28810960/talk-to-the-hand-u-s-army-biophysical-testing
#11
William R Santee, Adam W Potter, Karl E Friedl
BACKGROUND: Many people are unaware of the science underlying the biophysical properties of Soldier clothing and personal protective equipment, yet there is a well-refined biomedical methodology initiated by Army physiologists in World War II. This involves a methodical progression of systematic material testing technologies, computer modeling, and human testing that enables more efficient development and rapid evaluation of new concepts for Soldier health and performance. Sophisticated manikins that sweat and move are a central part of this testing continuum...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28810348/-a-preliminary-discussion-on-the-contents-and-value-of-all-diseases-1-the-medical-bamboo-slips-unearthed-from-han-tomb-in-laoguanshan-of-chengdu
#12
Y Ye, Q Zhang, Y L Ren, J M Li
Among the medical bamboo slips unearthed from Han tomb in Laoguanshan of Chengdu, the Zhu bing (All Diseases) is a monograph to discuss the characteristics of signs and symptoms. Based on the differences of writing styles, diseases involved, expounding methods and writing rules, the book is divided, by the research team, into 2 parts: All Diseases(1) and All Diseases(2). All Diseases(1) includes over 130 slips, 2 000 characters with totally more than 100 disease names, containing multiple clinical disciplines...
May 28, 2017: Zhonghua Yi Shi za Zhi, Chinese Journal of Medical History
https://www.readbyqxmd.com/read/28810198/phthalate-metabolites-related-to-infertile-biomarkers-and-infertility-in-chinese-men
#13
Liangpo Liu, Heng Wang, Meiping Tian, Jie Zhang, Parinya Panuwet, Priya Esilda D'Souza, Dana Boyd Barr, Qingyu Huang, Yankai Xia, Heqing Shen
Although in vitro and in vivo laboratory studies have demonstrated androgen and anti-androgen effects on male reproduction from phthalate exposures, human studies still remain inconsistent. Therefore, a case-control study (n = 289) was conducted to evaluate the associations between phthalate exposures, male infertility risks, and changes in metabolomic biomarkers. Regional participants consisted of fertile (n = 150) and infertile (n = 139) males were recruited from Nanjing Medical University' affiliated hospitals...
August 12, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28809749/measurement-uncertainty-of-%C3%AE-glutamyltransferase-ggt-in-human-serum-by-four-approaches-using-different-quality-assessment-data
#14
Rui Zhou, Yanyan Qin, Hongyi Yin, Yanmin Yang, Qingtao Wang
BACKGROUND: Measurement uncertainty (MU) characterizes the dispersion of the quantity values attributed to a measurand. Although this concept was introduced to medical laboratories some years ago, not all medical researchers are familiar with it. Therefore, the evaluation and expression of MU must be highlighted. In this paper, the evaluation of MU is described by using four different approaches from different quality assessment data. METHODS: In accordance with Guide to the Expression of Uncertainty of Measurement (GUM) principles, human serum γ-glutamyltransferase (GGT) level was defined as the measurand...
August 15, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28809713/a-survey-on-biofeedback-and-actuation-in-wireless-body-area-networks-wban
#15
Rui Li, Daniel T H Lai, WeeSit Lee
Wireless Body Area Networks (WBAN) has attained increasing popularity as the next generation framework of wearable technologies for human monitoring. Invasive or non-invasive wearable sensors designed in WBAN are worn to gather vital information. Biofeedback is a recent concept where collected data is used to generate actuation signals in WBANs. Applications can be seen in various areas such as sports (e.g. locomotor velocity) or medical (e.g. blood pressure measurement). However, since the body is closely regulated, the next generation WBAN technology must be smart enough to react to monitored data...
August 10, 2017: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/28809677/application-of-the-4d-xcat-phantoms-in-biomedical-imaging-and-beyond
#16
W Paul Segars, B M W Tsui, Jing Cai, Fang-Fang Yin, George S K Fung, Ehsan Samei
The four dimensional (4D) eXtended CArdiac-Torso (XCAT) series of phantoms was developed to provide accurate computerized models of the human anatomy and physiology. The XCAT series encompasses a vast population of phantoms of varying ages from newborn to adult, each including parameterized models for the cardiac and respiratory motions. With great flexibility in the XCAT's design, any number of body sizes, different anatomies, cardiac or respiratory motions or patterns, patient positions and orientations, and spatial resolutions can be simulated...
August 10, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28809670/cardio-pulmonary-stethoscope-clinical-validation-with-heart-failure-and-hemodialysis-patients
#17
Magdy F Iskander, Todd B Seto, Ruthsenne Rg Perron, Eunjung Lim, Farhan Qazi
OBJECTIVE: The purpose of this study is to evaluate the accuracy of a noninvasive radiofrequency-based device, the Cardio-Pulmonary Stethoscope (CPS), to monitor heart and respiration rates and detect changes in lung water content in human experiments and clinical trials. METHODS: Three human populations (healthy subjects (n=4), heart failure (n=12) and hemodialysis (n=13) patients) were enrolled in this study. The study was conducted at the University of Hawaii and The Queen's Medical Center in Honolulu, HI...
August 14, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28809585/patient-autonomy-and-doctor-s-concern-a-case-of-intravenous-drug-abuser
#18
Alok Atreya, Tanuj Kanchan, Rajeev K Shah
Intravenous substance abuse is often associated with physical and psychological harm, and often requires urgent medical attention. We report a case of a young male who presented with life-threatening complications of intravenous drug abuse, but refused to give details or agree to the proposed treatment, raising concerns for the team of doctors. A compos mentis patient has a right to decide what should be done to his body. Medical management or surgical interventions cannot be initiated without the patient's consent even if these are lifesaving procedures, or a procedure meant to benefit the patient...
January 1, 2017: Medico-legal Journal
https://www.readbyqxmd.com/read/28808940/plasma-alpha-l-fucosidase-activity-in-chronic-inflammation-and-autoimmune-disorders-in-a-pediatric-cohort-of-hospitalized-patients
#19
Ildikó Endreffy, Geir Bjørklund, László Szerafin, Salvatore Chirumbolo, Mauricio A Urbina, Emőke Endreffy
Human α-fucosidase (EC 3.2.1.51) is an enzyme (hydrolase) of particular biological and medical interest, as the inherited deficiency in its activity leads to fucosidosis, a pathology belonging to severe glycoprotein lysosomal storage disorders. Although its importance has increased in latest years, data about its plasma level in children with inflammatory disorders are still lacking. In the present study, plasma activity of α-L-fucosidase-1 (FUCA-1) and its potential association with chronic inflammatory pathologies was evaluated in hospitalized individuals, both pediatric and adult ones...
August 14, 2017: Immunologic Research
https://www.readbyqxmd.com/read/28808688/adaptive-mistranslation-accelerates-the-evolution-of-fluconazole-resistance-and-induces-major-genomic-and-gene-expression-alterations-in-candida-albicans
#20
Tobias Weil, Rodrigo Santamaría, Wanseon Lee, Johan Rung, Noemi Tocci, Darren Abbey, Ana R Bezerra, Laura Carreto, Gabriela R Moura, Mónica Bayés, Ivo G Gut, Attila Csikasz-Nagy, Duccio Cavalieri, Judith Berman, Manuel A S Santos
Regulated erroneous protein translation (adaptive mistranslation) increases proteome diversity and produces advantageous phenotypic variability in the human pathogen Candida albicans. It also increases fitness in the presence of fluconazole, but the underlying molecular mechanism is not understood. To address this question, we evolved hypermistranslating and wild-type strains in the absence and presence of fluconazole and compared their fluconazole tolerance and resistance trajectories during evolution. The data show that mistranslation increases tolerance and accelerates the acquisition of resistance to fluconazole...
July 2017: MSphere
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