keyword
MENU ▼
Read by QxMD icon Read
search

Vestibular

keyword
https://www.readbyqxmd.com/read/29792920/inner-ear-drug-delivery-recent-advances-challenges-and-perspective
#1
Jinsong Hao, S Kevin Li
Effective and safe treatment of auditory and vestibular diseases has become increasingly dependent on inner ear drug delivery systems. This review highlights recent advances in inner ear drug delivery research and technologies. The focus is on strategies to overcome delivery barriers and to improve drug residence and targeting, with special attention to in vivo animal and human studies. The research in gene and stem cell delivery to the inner ear is briefly reviewed. Newly developed research tools to address experimental challenges and safety issues are discussed...
May 21, 2018: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29792509/modulation-of-excitability-in-the-temporoparietal-junction-relieves-virtual-reality-sickness
#2
Naoyuki Takeuchi, Takayuki Mori, Yoshimi Suzukamo, Shin-Ichi Izumi
Virtual reality (VR) immersion often provokes subjective discomfort and postural instability, so called VR sickness. The neural mechanism of VR sickness is speculated to be related to visual-vestibular information mismatch and/or postural instability. However, the approaches proposed to relieve VR sickness through modulation of brain activity are poorly understood. Using transcranial direct current stimulation (tDCS), we aimed to investigate whether VR sickness could be relieved by the modulation of cortical excitability in the temporoparietal junction (TPJ), which is known to be involved in processing of both vestibular and visual information...
May 24, 2018: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/29792303/recurrent-spontaneous-vertigo-with-interictal-headshaking-nystagmus
#3
Sun-Uk Lee, Jeong-Yoon Choi, Hyo-Jung Kim, Ji-Soo Kim
OBJECTIVE: To define a disorder characterized by recurrent spontaneous vertigo (RSV) of unknown etiology and interictal headshaking nystagmus (HSN). METHODS: We characterized HSN in 35 patients with RSV-HSN compared to that recorded in randomly selected patients with compensated vestibular neuritis (VN), vestibular migraine (VM), and Ménière disease (MD). RESULTS: The estimated time constant (TC) of the primary phase of HSN was 12 seconds (95% confidence interval [CI] 12-13) in patients with RSV-HSN, which was larger than those in patients with VN (5 seconds, 95% CI 4-5), VM (5 seconds, 95% CI 5-6), or MD (6 seconds, 95% CI 5-6)...
May 23, 2018: Neurology
https://www.readbyqxmd.com/read/29791616/short-and-long-latency-auditory-evoked-potentials-in-individuals-with-vestibular-dysfunction
#4
Valdete Alves Valentins Dos Santos Filha, Mirtes Bruckmann, Michele Vargas Garcia
Purpose Evaluate the auditory pathway at the brainstem and cortical levels in individuals with peripheral vestibular dysfunction. Methods The study sample was composed 19 individuals aged 20-80 years that presented exam results suggestive of Peripheral Vestibular Disorder (PVD) or Vestibular Dysfunction (VD). Participants underwent evaluation of the auditory pathway through Brainstem Auditory Evoked Potentials (BAEP) (short latency) and P1, N1, P2, N2, and P300 cortical potentials (long latency). Results Nine individuals presented diagnosis of VD and 10 participants were diagnosed with PVD...
2018: CoDAS
https://www.readbyqxmd.com/read/29790432/transoral-endoscopic-thyroidectomy-vestibular-approach-a-preliminary-framework-for-assessment-and-safety
#5
Jonathon Russell, Angkoon Anuwong, Gianlorenzo Dionigi, William B Inabnet, Hoon Yub Kim, Gregory W Randolph, Jeremy D Richmon, Ralph P Tufano
Transoral endoscopic thyroidectomy vestibular approach (TOETVA) is a new approach to the central neck that avoids an anterior cervical incision. This approach can be performed with endoscopic or robotic assistance and offers access to the bilateral central neck. It has been completed safely in both North American and, even more extensively, international populations. With any new technology or approach, complications during the learning curve, expense, instrument limitations, and overall safety may affect its ultimate adoption and utility...
May 23, 2018: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29789090/the-giant-hand-illusion-experienced-on-a-simulator
#6
Petr Frantis, Antonin Petru
BACKGROUND: This paper discusses a special kind of a sensory illusion-the Giant Hand illusion-that was experienced during an exercise on a flight simulator equipped with a VR headset. In the first part we describe spatial disorientation and the function of the vestibular apparatus during flight and its consequences. In this part, the sensory illusion simulator used for the experiment is mentioned. In the second part we describe the simulator and test flight. In the third part we discuss data retrieved during simulator flights that are important for explaining the Giant Hand illusion...
June 1, 2018: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/29788991/bilateral-tympanokeratomas-cholesteatomas-with-bilateral-otitis-media-unilateral-otitis-interna-and-acoustic-neuritis-in-a-dog
#7
Liv Østevik, Kathrine Rudlang, Tuva Holt Jahr, Mette Valheim, Bradley Lyndon Njaa
BACKGROUND: An aural cholesteatoma, more appropriately named tympanokeratoma, is an epidermoid cyst of the middle ear described in several species, including dogs, humans and Mongolian gerbils. The cyst lining consists of stratified, keratinizing squamous epithelium with central accumulation of a keratin debris. This case report describes vestibular ganglioneuritis and perineuritis in a dog with chronic otitis, bilateral tympanokeratomas and presumed extension of otic infection to the central nervous system...
May 22, 2018: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/29788412/treatment-of-mal-de-debarquement-syndrome-in-a-deployed-environment
#8
Stephanie M Schenk, Jacklyn M Wagner, Jarrod A Miller, Tracey M Lyons-White, Emilee C Venn, Michael D April, Brit Long, Steven G Schauer, Joshua J Oliver
We report the case of a 26-year-old Caucasian female with persistent sensations of forward and reverse movement with spontaneous onset. This worsened over 4 wk. The patient reported an episode of these symptoms 5 mo prior, which lasted for 3 mo before improving. Our case details the treatment of Mal de Debarquement syndrome, or Disembarkment Syndrome, in a deployed military environment. Mal de Debarquement was a term originally coined to describe the persistent sensation of rocking back and forth after disembarking a boat and returning to land...
May 18, 2018: Military Medicine
https://www.readbyqxmd.com/read/29787866/handedness-dependent-functional-organizational-patterns-within-the-bilateral-vestibular-cortical-network-revealed-by-fmri-connectivity-based-parcellation
#9
V Kirsch, R Boegle, D Keeser, E Kierig, B Ertl-Wagner, T Brandt, M Dieterich
Current evidence points towards a vestibular cortex that involves a multisensory bilateral temporo-parietal-insular network with a handedness-dependent hemispheric lateralization. This study aimed to identify handedness-dependent organizational patterns of (lateralized and non-lateralized) functional subunits within the human vestibular cortex areas. 60 healthy volunteers (30 left-handed and 30 right-handed) were examined on a 3T MR scanner using resting state functional MRI (fMRI). The data was analyzed in four major steps using a functional connectivity based parcellation (fCBP) approach: (1) independent component analysis (ICA) on a whole brain level to identify different resting state networks (RSN); (2) creation of a vestibular informed mask from four whole brain ICs that included reference coordinates of the vestibular network extracted from meta-analyses of vestibular neuroimaging experiments; (3) Re-ICA confined to the vestibular informed mask; (4) cross-correlation of the activated voxels within the vestibular subunits (parcels) to each other (P-to-P) and to the whole-brain RSN (P-to-RSN)...
May 19, 2018: NeuroImage
https://www.readbyqxmd.com/read/29786462/multi-institutional-study-of-the-variability-in-target-delineation-for-six-targets-commonly-treated-with-radiosurgery
#10
Helena Sandström, Hidefumi Jokura, Caroline Chung, Iuliana Toma-Dasu
BACKGROUND: Although accurate delineation of the target is a key factor of success in radiosurgery there are no consensus guidelines for target contouring. AIM: The aim of the present study was therefore to quantify the variability in target delineation and discuss the potential clinical implications, for six targets regarded as common in stereotactic radiosurgery. MATERIAL AND METHODS: Twelve Gamma Knife centers participated in the study by contouring the targets and organs at risks and performing the treatment plans...
May 22, 2018: Acta Oncologica
https://www.readbyqxmd.com/read/29785677/analysis-of-the-frequency-of-visualization-of-morphological-variations-in-anatomical-bone-features-in-the-mandibular-interforaminal-region-through-cone-beam-computed-tomography
#11
Marilza do Carmo Oliveira, Tamara Kerber Tedesco, Thais Gimenez, Sergio Allegrini
PURPOSE: The purpose of this study was to analyze the frequency of visualization of anatomical bone features and their possible variations in the mandibular interforaminal region through cone-beam computed tomography (CBCT). METHODS: This is a cross-sectional study that evaluated CBCT scans of the mandible of 141 women and 61 men, obtained by imaging archives from two private clinics of dental radiology. The study analyzed the frequency of visualization of: lingual symphyseal foramen (LSF), additional mental foramen (AdMF), absence of mental foramen (AbMF), mandibular incisive canal (MIC), and anterior loop (AL)...
May 21, 2018: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/29785522/non-invasive-vagus-nerve-stimulation-significantly-improves-quality-of-life-in-patients-with-persistent-postural-perceptual-dizziness
#12
Ozan E Eren, Filipp Filippopulos, Kristina Sönmez, Ken Möhwald, Andreas Straube, Florian Schöberl
Persistent postural-perceptual dizziness (PPPD) is one of the most common causes of chronic vestibular disorders, with a substantial portion of the affected patients showing no significant improvement to standard therapies (i.e., pharmacotherapy, behavioral psychotherapy). Patients with PPPD have been shown to have a significant comorbidity with anxiety disorders and depression. Further, these patients show an activation of the autonomic nervous system resulting in symptoms such as nausea, increase of heart rate, and sweating...
May 21, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29784077/effects-of-ketamine-compared-with-urethane-anesthesia-on-vestibular-sensory-evoked-potentials-and-systemic-physiology-in-mice
#13
Choongheon Lee, Timothy A Jones
The injectable anesthetic mixture ketamine-xylazine is commonly used for electrophysiologic experiments in laboratory animals, especially rodents. General anesthesia can induce significant changes in systemic physiology, including those that compromise neural function, thus introducing research confounds. The extent of such concerns varies by agent. Here in mice, we compared the effects of ketamine-xylazine and urethane-xylazine anesthesia on systemic physiologic parameters and the vestibular sensory evoked potential (VsEP), a tool used commonly to assess peripheral vestibular function...
May 1, 2018: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/29782443/association-between-vestibular-vertigo-and-motor-vehicle-accidents-data-from-the-2016-national-health-interview-survey
#14
Eric X Wei, Yuri Agrawal
Recent evidence has shown that individuals with vestibular impairment have higher rates of self-reported driving difficulty compared with individuals without vestibular impairment. However, it is unknown whether individuals with vestibular impairment are more likely to be involved in motor vehicle accidents. We used data from the 2016 National Health Interview Survey of U.S. adults to evaluate whether individuals with vestibular vertigo are more likely to experience motor vehicle accidents relative to individuals without vestibular vertigo...
May 18, 2018: Ear and Hearing
https://www.readbyqxmd.com/read/29781505/cerebral-vasculopathy-in-childhood-neurofibromatosis-type-2-cause-for-concern
#15
Karine Lascelles, Shazia Afridi, Ata Siddiqui, Cheryl Hemingway, Rosalie Ferner, Vijeya Ganesan
Unlike adult neurofibromatosis type 2 (NF2), which presents with symptoms related to bilateral vestibular schwannomas, children with NF2 most frequently present with ocular, dermatological, and neurological symptoms. Arteriopathy, a well-established feature in neurofibromatosis type 1, is not a widely recognized feature of NF2. Here we report three children with NF2 with cerebral arteriopathy and/or arterial ischaemic stroke. Bevacizumab, a vascular endothethial growth factor inhibitor, is an established treatment for rapidly growing vestibular schwannomas; however, it carries a risk of both ischaemic and haemorrhagic stroke...
May 21, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29781154/neuroglial-ectopia-of-the-vestibular-nerve-masquerading-as-a-vestibular-schwannoma-a-case-report
#16
John P Sheppard, Carlito Lagman, Thien Nguyen, Négar Khanlou, Quinton Gopen, Isaac Yang
Neuroglial ectopia is a rare entity of undetermined clinical significance. Here, we report a unique case of neuroglial ectopia of the vestibular nerve. A 27-year-old pharmacy student with a previous radiological diagnosis of vestibular schwannoma presented to our clinic for surgical evaluation. Magnetic resonance imaging (MRI) of the brain revealed a 17-mm T1 hypo- to isointense, T2 iso- to hyperintense, poorly enhancing left cerebellopontine angle mass extending into the left internal auditory canal compatible by imaging with a vestibular schwannoma...
May 20, 2018: Neuropathology: Official Journal of the Japanese Society of Neuropathology
https://www.readbyqxmd.com/read/29779876/linear-self-motion-cues-support-the-spatial-distribution-and-stability-of-hippocampal-place-cells
#17
Ryan E Harvey, Stephanie A Rutan, Gabrielle R Willey, Jennifer J Siegel, Benjamin J Clark, Ryan M Yoder
The vestibular system provides a crucial component of place-cell and head-direction cell activity [1-7]. Otolith signals are necessary for head-direction signal stability and associated behavior [8, 9], and the head-direction signal's contribution to parahippocampal spatial representations [10-14] suggests that place cells may also require otolithic information. Here, we demonstrate that self-movement information from the otolith organs is necessary for the development of stable place fields within and across sessions...
May 10, 2018: Current Biology: CB
https://www.readbyqxmd.com/read/29779610/surgical-anatomy-for-hemifacial-spasm
#18
P Mercier, F Bernard
Classically in the cerebello-pontine angle the facial (CN VII) and vestibular-cochlear (CN VIII) nerves should run parallel with the anterior inferior cerebellar artery, whereas the lower nerves (CN IX-XI) continue with the posterior-inferior-cerebellar artery (PICA). In fact, this is not always true, particularly when dealing with hemispasm surgery where the relationships between CN VII, CN VIII and PICA are often different and closer. Knowledge of anatomical bases in surgical situation will help neurosurgeons to appreciate anatomical nuances, that are important to increase effectiveness and safety of hemifacial spasm surgery...
May 17, 2018: Neuro-Chirurgie
https://www.readbyqxmd.com/read/29779050/proprioceptive-loss-and-the-perception-control-and-learning-of-arm-movements-in-humans-evidence-from-sensory-neuronopathy
#19
R Chris Miall, Nick M Kitchen, Se-Ho Nam, Hannah Lefumat, Alix G Renault, Kristin Ørstavik, Jonathan D Cole, Fabrice R Sarlegna
It is uncertain how vision and proprioception contribute to adaptation of voluntary arm movements. In normal participants, adaptation to imposed forces is possible with or without vision, suggesting that proprioception is sufficient; in participants with proprioceptive loss (PL), adaptation is possible with visual feedback, suggesting that proprioception is unnecessary. In experiment 1 adaptation to, and retention of, perturbing forces were evaluated in three chronically deafferented participants. They made rapid reaching movements to move a cursor toward a visual target, and a planar robot arm applied orthogonal velocity-dependent forces...
May 19, 2018: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/29778132/cervical-vestibular-evoked-myogenic-potentials-cvemps-evoked-by-air-conducted-stimuli-in-patients-with-functional-neck-dissection
#20
Hasan Demirhan, Bahtiyar Hamit, Özgür Yiğit
OBJECTIVE: Cervical vestibular-evoked myogenic potentials (cVEMPs) are short-latency vestibulocollic reflexes. The damage on any point of the vestibulocollic reflex pathway could affect the cVEMPs. Whether neck dissection has an effect on the sacculocollic pathway, and consequently on cVEMPs, remains unexplored. The aim of this study was to evaluate the cVEMP findings in patients with functional neck dissection without vestibular symptoms. PATIENTS AND METHODS: This cross-sectional study design, 20 patients who had undergone unilateral neck dissection with sparing of the accessory nerve, SCM and internal jugular vein, were included...
June 2018: Journal of the National Medical Association
keyword
keyword
7468
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"