Dawei Wang, Yu Feng, Min Yang, Haihui Sun, Qingchen Zhang, Rongrong Wang, Shuqing Tong, Rui Su, Yan Jin, Yunshan Wang, Zhiming Lu, Lihui Han, Yundong Sun
It was found that with the increase of drug use years, the content of tryptamine associated with neuropsychiatric disorders gradually increased. The prediction models based on oral microbiome and metabolome could effectively predict the methamphetamine (METH) smoking. Our study provides novel insights into the exploration of the molecular mechanisms regulating the toxic damage and addiction of METH as well as new ideas for early prevention and treatment strategies of METH addiction.
December 19, 2023: MSystems