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Robert Osher

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https://www.readbyqxmd.com/read/27698550/intravitreal-methotrexate-infusion-for-proliferative-vitreoretinopathy
#1
Ama Sadaka, Robert A Sisk, James M Osher, Okan Toygar, Melinda K Duncan, Christopher D Riemann
PURPOSE: The purpose of this study was to evaluate intravitreal methotrexate infusion (IMI) during pars plana vitrectomy (PPV) for retinal detachment in patients with high risk for the development of proliferative vitreoretinopathy (PVR). METHODS: Patients presenting with severe recurrent PVR with tractional retinal detachment and/or a history of severe ocular inflammation were treated with IMI. Clinical outcomes were determined from a retrospective medical chart review...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27515135/haptoglobin-or-hemopexin-therapy-prevents-acute-adverse-effects-of-resuscitation-after-prolonged-storage-of-red-cells
#2
Jan A Graw, Claire Mayeur, Ivy Rosales, Yumin Liu, Venkata S Sabbisetti, Frank E Riley, Osher Rechester, Rajeev Malhotra, H Shaw Warren, Robert B Colvin, Joseph V Bonventre, Donald B Bloch, Warren M Zapol
BACKGROUND: Extracellular hemoglobin and cell-free heme are toxic breakdown products of hemolyzed erythrocytes. Mammals synthesize the scavenger proteins haptoglobin and hemopexin, which bind extracellular hemoglobin and heme, respectively. Transfusion of packed red blood cells is a lifesaving therapy for patients with hemorrhagic shock. Because erythrocytes undergo progressive deleterious morphological and biochemical changes during storage, transfusion of packed red blood cells that have been stored for prolonged intervals (SRBCs; stored for 35-40 days in humans or 14 days in mice) increases plasma levels of cell-free hemoglobin and heme...
September 27, 2016: Circulation
https://www.readbyqxmd.com/read/27311978/materials-in-the-vitreous-during-cataract-surgery-nature-and-incidence-with-two-cases-of-histological-confirmation
#3
Andrew W Kam, Tony S Chen, Sarah B Wang, Neeranjali S Jain, Aaron Yj Goh, Christopher P Douglas, Penny A McKelvie, Ashish Agar, Robert H Osher, Ian C Francis
BACKGROUND: To identify and classify materials in the vitreous (MIV) observed during phacoemulsification cataract surgery (phaco). DESIGN: Prospective, consecutive, observational case series at one ophthalmic day surgery in Sydney, Australia PARTICIPANTS: 767 consecutive phaco cases. Cases were excluded if there was posterior capsule rupture or vitreous loss intraoperatively. METHODS: For each patient, age, gender, baseline corrected distance visual acuity (CDVA), presence of pseudoexfoliation, nuclear sclerosis grade and phacoemulsification ultrasound time were recorded...
June 17, 2016: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/27113889/polychromasia-capsulare-determining-the-cause-of-multicolored-iridescence-of-the-anterior-lens-capsule
#4
Robert H Osher, Victoria J Miller, Ralph C Eagle, Marion J Siegman, David Wang, Deborah A Osborn
UNLABELLED: Polychromasia capsulare is a rare condition in which the anterior lens capsule exhibits an extraordinary array of colors during biomicroscopy that change with the incident angle of direct illumination consistent with iridescence. We present the case of a 59-year-old man with bilateral polychromasia capsulare who had successful cataract surgery. Routine light microscopy of the patient's capsulorhexis specimen was normal; however, transmission electron microscopy showed an unusual pattern of polygonal profiles with a periodicity estimated to be approximately 400 to 500 nm...
April 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/26300623/preretinal-hemorrhage-as-a-presenting-sign-of-idiopathic-macular-telangiectasia-type-2
#5
James M Osher, Robert A Sisk, Michael R Petersen
We report three cases of idiopathic macular telangiectasia type 2 with temporally decentered preretinal hemorrhage as the presenting sign. The preretinal blood obscured the telangiectatic vessels such that the diagnosis was only evident by fluorescein angiography of the fellow eyes, which had near-normal vision. The preretinal hemorrhage was associated with Valsalva maneuver in one patient and with type 3 subretinal neovascularization in one patient. We speculate that the vascular dilations in idiopathic macular telangiectasia type 2 may increase patients' susceptibility to rupture and hemorrhage with increased venous pressure...
2015: Clinical Ophthalmology
https://www.readbyqxmd.com/read/25862378/influence-of-light-exposure-during-early-life-on-the-age-of-onset-of-bipolar-disorder
#6
REVIEW
Michael Bauer, Tasha Glenn, Martin Alda, Ole A Andreassen, Elias Angelopoulos, Raffaella Ardau, Christopher Baethge, Rita Bauer, Bernhard T Baune, Frank Bellivier, Robert H Belmaker, Michael Berk, Thomas D Bjella, Letizia Bossini, Yuly Bersudsky, Eric Yat Wo Cheung, Jörn Conell, Maria Del Zompo, Seetal Dodd, Bruno Etain, Andrea Fagiolini, Mark A Frye, Kostas N Fountoulakis, Jade Garneau-Fournier, Ana Gonzalez-Pinto, John F Gottlieb, Hirohiko Harima, Stefanie Hassel, Chantal Henry, Apostolos Iacovides, Erkki T Isometsä, Flávio Kapczinski, Sebastian Kliwicki, Barbara König, Rikke Krogh, Mauricio Kunz, Beny Lafer, Erik R Larsen, Ute Lewitzka, Carlos Lopez-Jaramillo, Glenda MacQueen, Mirko Manchia, Wendy Marsh, Mónica Martinez-Cengotitabengoa, Ingrid Melle, Scott Monteith, Gunnar Morken, Rodrigo Munoz, Fabiano G Nery, Claire O'Donovan, Yamima Osher, Andrea Pfennig, Danilo Quiroz, Raj Ramesar, Natalie Rasgon, Andreas Reif, Philipp Ritter, Janusz K Rybakowski, Kemal Sagduyu, Ângela Miranda-Scippa, Emanuel Severus, Christian Simhandl, Dan J Stein, Sergio Strejilevich, Ahmad Hatim Sulaiman, Kirsi Suominen, Hiromi Tagata, Yoshitaka Tatebayashi, Carla Torrent, Eduard Vieta, Biju Viswanath, Mihir J Wanchoo, Mark Zetin, Peter C Whybrow
BACKGROUND: Environmental conditions early in life may imprint the circadian system and influence response to environmental signals later in life. We previously determined that a large springtime increase in solar insolation at the onset location was associated with a younger age of onset of bipolar disorder, especially with a family history of mood disorders. This study investigated whether the hours of daylight at the birth location affected this association. METHODS: Data collected previously at 36 collection sites from 23 countries were available for 3896 patients with bipolar I disorder, born between latitudes of 1...
May 2015: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/25763463/stability-of-the-acrysof-toric-intraocular-lens-in-combined-cataract-surgery-and-transconjunctival-sutureless-vitrectomy
#7
Brian W Toussaint, Matthew F Appenzeller, Daniel M Miller, Michael R Petersen, Robert E Foster, Robert H Osher, Michael E Snyder, Christine K Hunt, Robert A Sisk, Christopher D Riemann
PURPOSE: To report the outcomes of combined cataract surgery with toric intraocular lens (IOL) implantation when performed in conjunction with transconjunctival sutureless pars plana vitrectomy. DESIGN: Retrospective interventional case series. PARTICIPANTS: Consecutive series of 55 eyes of 51 patients from April 2007 to December of 2010. METHODS: All eyes underwent combined simultaneous small incision cataract surgery, toric IOL implantation, and transconjunctival sutureless vitrectomy surgery...
June 2015: Retina
https://www.readbyqxmd.com/read/24953482/relationship-between-sunlight-and-the-age-of-onset-of-bipolar-disorder-an-international-multisite-study
#8
Michael Bauer, Tasha Glenn, Martin Alda, Ole A Andreassen, Elias Angelopoulos, Raffaella Ardau, Christopher Baethge, Rita Bauer, Frank Bellivier, Robert H Belmaker, Michael Berk, Thomas D Bjella, Letizia Bossini, Yuly Bersudsky, Eric Yat Wo Cheung, Jörn Conell, Maria Del Zompo, Seetal Dodd, Bruno Etain, Andrea Fagiolini, Mark A Frye, Kostas N Fountoulakis, Jade Garneau-Fournier, Ana González-Pinto, Hirohiko Harima, Stefanie Hassel, Chantal Henry, Apostolos Iacovides, Erkki T Isometsä, Flávio Kapczinski, Sebastian Kliwicki, Barbara König, Rikke Krogh, Mauricio Kunz, Beny Lafer, Erik R Larsen, Ute Lewitzka, Carlos Lopez-Jaramillo, Glenda MacQueen, Mirko Manchia, Wendy Marsh, Mónica Martinez-Cengotitabengoa, Ingrid Melle, Scott Monteith, Gunnar Morken, Rodrigo Munoz, Fabiano G Nery, Claire O'Donovan, Yamima Osher, Andrea Pfennig, Danilo Quiroz, Raj Ramesar, Natalie Rasgon, Andreas Reif, Philipp Ritter, Janusz K Rybakowski, Kemal Sagduyu, Ângela M Scippa, Emanuel Severus, Christian Simhandl, Dan J Stein, Sergio Strejilevich, Ahmad Hatim Sulaiman, Kirsi Suominen, Hiromi Tagata, Yoshitaka Tatebayashi, Carla Torrent, Eduard Vieta, Biju Viswanath, Mihir J Wanchoo, Mark Zetin, Peter C Whybrow
BACKGROUND: The onset of bipolar disorder is influenced by the interaction of genetic and environmental factors. We previously found that a large increase in sunlight in springtime was associated with a lower age of onset. This study extends this analysis with more collection sites at diverse locations, and includes family history and polarity of first episode. METHODS: Data from 4037 patients with bipolar I disorder were collected at 36 collection sites in 23 countries at latitudes spanning 3...
2014: Journal of Affective Disorders
https://www.readbyqxmd.com/read/24864329/optimizing-precision-in-toric-lens-selection-by-combining-keratometry-techniques
#9
COMPARATIVE STUDY
Andrew W Browne, Robert H Osher
PURPOSE: To increase precision in toric intraocular lens selection by reducing the frequency of outliers that arise from technology-dependent variability during the preoperative assessment for routine cataract surgery. METHODS: Mean preoperative values for absolute sphere, amount of astigmatism, and steepest cylindrical axis were obtained for 87 eyes (54 patients) each with a manual keratometer and four automated keratometers. The mean sphere, amount of astigmatism, and steepest cylindrical axis across five technologies for each eye were defined as the meld sphere, meld astigmatism, and meld axis, respectively...
January 2014: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/24590946/how-health-care-reform-can-transform-the-health-of-criminal-justice-involved-individuals
#10
REVIEW
Josiah D Rich, Redonna Chandler, Brie A Williams, Dora Dumont, Emily A Wang, Faye S Taxman, Scott A Allen, Jennifer G Clarke, Robert B Greifinger, Christopher Wildeman, Fred C Osher, Steven Rosenberg, Craig Haney, Marc Mauer, Bruce Western
Provisions of the Affordable Care Act offer new opportunities to apply a public health and medical perspective to the complex relationship between involvement in the criminal justice system and the existence of fundamental health disparities. Incarceration can cause harm to individual and community health, but prisons and jails also hold enormous potential to play an active and beneficial role in the health care system and, ultimately, to improving health. Traditionally, incarcerated populations have been incorrectly viewed as isolated and self-contained communities with only peripheral importance to the public health at large...
March 2014: Health Affairs
https://www.readbyqxmd.com/read/24404605/prospective-multicenter-study-of-toric-iol-outcomes-when-dual-zone-automated-keratometry-is-used-for-astigmatism-planning
#11
MULTICENTER STUDY
Richard Potvin, Kjell Gunnar Gundersen, Samuel Masket, Robert H Osher, Michael E Snyder, Robin Vann, Kerry D Solomon, Warren E Hill
PURPOSE: To evaluate clinical outcomes when toric intraocular lens (IOL) calculations are based on the keratometric output from the Lenstar LS-900 dual zone automated keratometer (Haag-Streit AG, Koeniz, Switzerland). METHODS: Eligible subjects presenting for toric IOL implantation at five sites were measured with a dual-zone automated keratometer. The data were used to plan the power and angle of the toric IOL to be implanted. Refractive and visual acuity status were checked at 1 and 3 months postoperatively...
December 2013: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/24230992/reward-sensitivity-and-anger-in-euthymic-bipolar-disorder
#12
Or Duek, Yamima Osher, Robert H Belmaker, Yuly Bersudsky, Ora Kofman
According to the hypersensitive behavioral approach system (BAS) model of bipolar disorder (BP), hypersensitivity of the BAS is a trait that should be present even in the euthymic state. This would be expected to result in increased anger and reward sensitivity, both of which are related to the approach system. This study examined these predictions through the use of tasks that assess different aspects of the BAS: reward sensitivity, anger and impulsivity. These characteristics were assessed using the probabilistic classification task (PCT), ultimatum game (UG) and single key impulsivity paradigm (SKIP), respectively...
January 30, 2014: Psychiatry Research
https://www.readbyqxmd.com/read/24016348/intraoperative-real-time-aberrometry-during-refractive-cataract-surgery-with-a-sequentially-shifting-wavefront-device
#13
COMPARATIVE STUDY
Ronald R Krueger, William Shea, Yan Zhou, Robert Osher, Stephen G Slade, David F Chang
PURPOSE: To introduce a new sequential wavefront device with rapid sampling that can be used as an intraoperative, real-time aberrometer/refractometer for immediate diagnosis and management of refractive outcomes during cataract surgery. METHODS: A unique wavefront device uses a rotating prismatic mirror to rapidly shift the incident wavefront emanating from the eye through an aperture for analysis of a sequentially sampled wavefront segment. The sampled segment is then focused onto a quad detector that localizes its angular displacement of the sampled segment's wavefront gradient...
September 2013: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/23332261/cataract-surgical-problem-february-consultation
#14
Robert H Osher, Geoffrey C Tabin, Zoltan Z Nagy, Alan S Crandall, Amar Agarwal, Soosan Jacob, David F Chang, Douglas D Koch, William J Fishkind, Arup Chakrabarti
No abstract text is available yet for this article.
February 2013: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/22999610/cataract-surgical-problem-october-consultation
#15
Robert H Osher, Marie-José Tassignon, David F Chang, Ali Al-Rajhi, Mark Packer, Sadeer B Hannush, Thomas A Oetting, Stephen H Johnson, Steven G Safran
No abstract text is available yet for this article.
October 2012: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/22999599/rescue-technique-for-salvaging-toric-intraocular-lens-alignment
#16
Amaryllis Avakian, Robert H Osher
Accurate alignment of a toric intraocular lens (IOL) is a requisite to achieving the intended reduction in astigmatism at the time of cataract surgery. However, it requires a reasonably clear view of the limbal vascular anatomy, which is sometimes altered by chemosis from a subconjunctival anesthetic injection or a hemorrhage. We describe a technique that can quickly restore vascular anatomy and facilitate toric IOL alignment.
October 2012: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/22727989/intentional-extreme-anisometropic-pseudophakic-monovision-new-approach-to-the-cataract-patient-with-longstanding-diplopia
#17
Robert H Osher, Karl C Golnik, Graham Barrett, Kimiya Shimizu
PURPOSE: To determine whether extreme pseudophakic monovision can reduce or eliminate diplopia in patients with cataract and longstanding acquired strabismus. SETTING: Department of Ophthalmology, University of Cincinnati, and the Cincinnati Eye Institute, Cincinnati, Ohio, USA. DESIGN: Case series. METHODS: Intentional extreme monovision was created in patients with stable diplopia having cataract surgery. Intraocular lens selection was targeted for emmetropia in 1 eye and at least 3...
August 2012: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/22108112/simulation-of-toric-intraocular-lens-results-manual-keratometry-versus-dual-zone-automated-keratometry-from-an-integrated-biometer
#18
MULTICENTER STUDY
Warren Hill, Robert Osher, David Cooke, Kerry Solomon, Helga Sandoval, Rosario Salas-Cervantes, Richard Potvin
PURPOSE: To evaluate simulated clinical outcomes in patients with toric intraocular lenses (IOLs) calculated on the basis of dual-zone automated keratometry from an integrated optical biometer, relative to manual keratometry. SETTING: Private practice, Mesa, Arizona, USA. DESIGN: Comparative case series. METHODS: Patient records at 4 clinical sites were reviewed to identify patients who had manual keratometry and biometry with the Lenstar LS 900 recorded before toric IOL implantation and refractive follow-up data after implantation...
December 2011: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/20117722/multifocal-iris-sphincter-ruptures-new-sign-of-the-lens-iris-diaphragm-retropulsion-syndrome
#19
Robert H Osher, James M Osher, Robert J Cionni
We describe the case of a 78-year-old highly myopic woman who had bilateral phacoemulsification with posterior chamber intraocular lens implantation. During surgery, the anterior chamber was extremely deep and the pupil was excessively dilated, consistent with lens-iris diaphragm retropulsion syndrome (LIDRS). Subsequent biomicroscopy revealed multifocal iris sphincter ruptures, a new finding associated with LIDRS.
January 2010: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/19465289/visual-outcome-comparison-of-unilateral-versus-bilateral-implantation-of-apodized-diffractive-multifocal-intraocular-lenses-after-cataract-extraction-prospective-6-month-study
#20
COMPARATIVE STUDY
Robert J Cionni, Robert H Osher, Michael E Snyder, Michael L Nordlund
PURPOSE: To evaluate the visual outcomes and patient satisfaction after unilateral implantation or stepwise bilateral implantation of an apodized diftractive multifocal intraocular lens (IOL). SETTING: Private practice, Cincinnati, Ohio, USA. METHODS: Patients requiring cataract surgery in 1 eye were recruited. AcrySof ReSTOR IOLs were implanted in 1 eye of patients with phakic contralateral eyes, patients with contralateral monofocal IOLs, and patients with a contralateral multifocal IOL of the same model...
June 2009: Journal of Cataract and Refractive Surgery
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