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https://www.readbyqxmd.com/read/29136168/a-prospective-study-of-the-incidence-of-juvenile-onset-recurrent-respiratory-papillomatosis-after-implementation-of-a-national-hpv-vaccination-program
#1
Daniel Novakovic, Alan T L Cheng, Yvonne Zurynski, Robert Booy, Paul J Walker, Robert Berkowitz, Henley Harrison, Robert Black, Christopher Perry, Shyan Vijayasekaran, David Wabnitz, Hannah Burns, Sepehr N Tabrizi, Suzanne M Garland, Elizabeth Elliott, Julia M L Brotherton
Background: Recurrent respiratory papillomatosis is a rare but morbid disease caused by human papillomavirus (HPV) types 6 and 11. Infection is preventable through HPV vaccination. Following an extensive quadrivalent HPV vaccination program (females 12-26 years in 2007-2009) in Australia, we established a method to monitor incidence and demographics of juvenile-onset recurrent respiratory papillomatosis (JORRP) cases. Methods: The Australian Paediatric Surveillance Unit undertakes surveillance of rare pediatric diseases by contacting practitioners monthly...
November 9, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29124900/unsatisfactory-exfoliative-anal-cytology-samples-15-year-experience-with-histologic-cytologic-and-molecular-follow-up
#2
Ruba Khattab, Emily McMeekin, Alan J Taege, James M Hekman, Jennifer A Brainard, Dawn Underwood, Gary W Procop, Charles D Sturgis
BACKGROUND: The incidence of anal carcinoma has risen in recent decades. Exfoliative cytology screening of selected high risk patients is performed in many centers. Unsatisfactory cytology results are frustrating to patients, clinicians, and laboratorians. The aim of this study is to ascertain outcomes of patients with non-diagnostic anal cytology. METHODS: A retrospective review of anal cytology testing performed at the Cleveland Clinic between 01/01/2001 and 12/31/2015 was performed...
November 10, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29123369/universal-proposal-strategies-of-anti-hpv-vaccination-for-adolescents-comparative-analysis-between-school-based-and-clinic-immunization-programs
#3
REVIEW
F Desiante, C Russo, A Giorgino, G Caputi, T Battista, R Cipriani, M Conversano
Introduction: A promising approach to increase teenager's adherence to immunization against HPV is the administration of vaccinations within the school facilities. The Local Health Unit of Taranto experienced two different vaccine strategy proposals in the twelve-year-olds: the first one was the usual active call strategy in the outpatient clinic, while the second one provided the involvement of the schools in the area. The aim of the study is to evaluate the results of the proposed vaccination strategies in both sexes and in towns of different sizes in order to identify an effective path for achieving vaccine coverage improvement...
September 2017: Journal of Preventive Medicine and Hygiene
https://www.readbyqxmd.com/read/29122884/complete-genome-sequence-of-a-novel-human-papillomavirus-isolated-from-oral-rinse
#4
Zigui Chen, Martin C S Wong, Po Yee Wong, Wendy C S Ho, Miaoyin Liang, Apple C M Yeung, Paul K S Chan
A novel human papillomavirus (HPV TG550) isolated from the oral rinse of a Chinese male resident was fully characterized. The L1 open reading frame of HPV TG550 shares 82.5% nucleotide sequence similarity with its closest relative, HPV166, and clusters within the species group Gammapapillomavirus 19.
November 9, 2017: Genome Announcements
https://www.readbyqxmd.com/read/29121862/human-papillomavirus-in-semen-and-the-risk-for-male-infertility-a-systematic-review-and-meta-analysis
#5
Zhangyan Lyu, Xiaoshuang Feng, Ni Li, Wei Zhao, Luopei Wei, Yuheng Chen, Wenjing Yang, Hongxia Ma, Bing Yao, Kai Zhang, Zhibin Hu, Hongbing Shen, Dong Hang, Min Dai
BACKGROUND: Human papillomavirus (HPV) is one of the most prevalent sexually transmitted viruses. Despite the increasing evidence of HPV prevalence in semen, the worldwide distribution of HPV types in semen and risk for male infertility remain inconclusive. METHODS: Four electronic databases were searched for English language studies conducted between January 1990 and December 2016 that reported HPV DNA prevalence in semen. Based on the PRISMA guidelines, HPV prevalence was estimated among general population and fertility clinic attendees, respectively, and heterogeneity testing was performed using Cochran's Q and I (2) statistics...
November 9, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29118826/prevalence-of-hpv-infection-in-hypopharyngeal-and-laryngeal-squamous-cell-carcinoma-at-thailand-s-largest-tertiary-referral-center
#6
Warut Pongsapich, Nitathip Eakkasem, Sontana Siritantikorn, Paveena Pithuksurachai, Kshidej Bongsabhikul, Cheerasook Chongkolwatana
Background: Following the well-established relationship between human papillomavirus (HPV) and cervical carcinoma, the carcinogenicity of this virus has also been confirmed in subsets of head and neck carcinoma (HNCA), but mainly in the oropharynx. Other subsites of HNCA with less known association to HPV have never been studied in Thailand. Accordingly, the aim of this study was to investigate the prevalence of HPV DNA in hypopharyngeal and laryngeal squamous cell carcinoma in Thai population...
2017: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/29090469/multiple-epidermolytic-acanthomas-mimicking-condyloma-a-retrospective-study-of-8-cases
#7
Tsung-Ju Lee, Yu-Hung Wu
BACKGROUND: Epidermolytic acanthoma (EA) is an uncommon benign cutaneous lesion. Multiple epidermolytic acanthomas (multiple EAs) are rarely reported. METHODS: We retrospectively identified patients diagnosed with multiple EAs between 2005 and 2017 from our dermatopathology database and analyzed their clinical, pathological, and immunohistochemical features. We also evaluated the association of multiple EAs with human papillomavirus (HPV) infection. RESULTS: In total, eight patients (average age 51 years; 3 : 1 male predominance) with multiple EAs were found...
October 31, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/29075776/defining-the-prevalence-and-prognostic-value-of-perineural-invasion-and-angiolymphatic-invasion-in-human-papillomavirus-positive-oropharyngeal-carcinoma
#8
William G Albergotti, Hannah L Schwarzbach, Shira Abberbock, Robert L Ferris, Jonas T Johnson, Umamaheswar Duvvuri, Seungwon Kim
Importance: Recently, the American Joint Committee on Cancer (AJCC) updated its staging system for human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC). The prognostic significance of perineural invasion (PNI) and angiolymphatic invasion (ALI) within this staging system is unknown. Objective: To examine the prevalence and prognostic significance of PNI and ALI in HPV-positive OPSCC. Design, Setting, and Participants: A retrospective review was performed of all patients with HPV-positive OPSCC treated surgically at the University of Pittsburgh Medical Center from January 1, 1980, through December 31, 2015, with at least 1 year of follow-up or death within 1 year...
October 26, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29074185/what-explains-the-different-rates-of-human-papillomavirus-vaccination-among-adolescent-males-and-females-in-the-united-states
#9
Yoonyoung Choi, Efe Eworuke, Richard Segal
PURPOSE: To identify factors that explain differences in HPV vaccination rates for male and female adolescents and to determine self-reported barriers by parents affecting vaccination decisions. METHODS: The sample included adolescents 13-17 years old with a vaccination record documented in the 2012 and 2013 National Immunization Survey-Teen dataset. A logistic regression model was developed with 13 socio-demographic factors and survey year, along with significant interaction pairs with gender...
December 2016: Papillomavirus Research
https://www.readbyqxmd.com/read/29074179/hpv-vaccination-intention-among-male-clients-of-a-large-sti-outpatient-clinic-in-amsterdam-the-netherlands
#10
E Marra, C J Alberts, G D Zimet, T G W M Paulussen, T Heijman, A A Hogewoning, G J B Sonder, J S Fennema, H J C de Vries, M F Schim van der Loeff
We explored HPV vaccination intention and its determinants among male clients of the sexually transmitted infections (STI) clinic in Amsterdam. In 2015, male clients aged ≥18 years were invited to complete a web-based questionnaire regarding HPV vaccination intention and socio-psychological determinants. Determinants (scale -3 to +3) were assessed with linear regression, stratified for men who have sex with men (MSM) (including men who have sex with men and women) and men who only have sex with women (MSW)...
December 2016: Papillomavirus Research
https://www.readbyqxmd.com/read/29074178/factors-affecting-hpv-vaccine-acceptance-in-west-austria-do-we-need-to-revise-the-current-immunization-scheme
#11
Wegene Borena, Anita Luckner-Hornischer, Franz Katzgraber, Dorothee Holm-von Laer
BACKGROUND: Austria introduced a school-based gender-neutral human papillomavirus (HPV) immunization program in February 2014. In order to assure high coverage, factors influencing acceptance of the vaccine need to be identified. In this study we aim to assess parents' attitude and related socio-demographic factors in relation to the newly implemented gender-neutral, school-based HPV Immunization program. METHODS: Parents of 4th grade school children in 20 randomly selected primary schools were asked to fill out questionnaires on socio-demographic factors and on the level of information and attitude towards HPV infection and HPV vaccine...
December 2016: Papillomavirus Research
https://www.readbyqxmd.com/read/29074177/high-specific-immune-response-to-a-bivalent-anti-hpv-vaccine-in-hiv-1-infected-men-in-s%C3%A3-o-paulo-brazil
#12
Adriele Fontes, Maria Antonieta Andreoli, Luisa Lina Villa, Tatiane Assone, Karen Gaester, Luiz A M Fonseca, Alberto Js Duarte, Jorge Casseb
INTRODUCTION: Infection with Human papillomavirus (HPV) has been reported as one of the most prevalent agent sexually transmitted diseases, but its true prevalence in men is not precisely known, mainly due to the near absence of symptoms. Moreover, few studies evaluating the post-vaccination immune response have been performed to date in men, hence the hypotheses tested in this study can be important to enable a better understanding of both the immunopathogenesis and the response to vaccination in HIV-infected patients, and to help in the elaboration of strategies of vaccination against HPV in the HIV-infected population...
December 2016: Papillomavirus Research
https://www.readbyqxmd.com/read/29074169/monitoring-the-impact-of-hpv-vaccine-in-males-considerations-and-challenges
#13
Julia M L Brotherton, Anna R Giuliano, Lauri E Markowitz, Eileen F Dunne, Gina S Ogilvie
In this article, we examine the issues involved if national or sub-national programs are considering extending post HPV vaccine introduction monitoring to include males. Vaccination programs are now being extended to include males in some countries, in order to improve population level HPV infection control and to directly prevent HPV-related disease in males such as anogenital warts and anal cancers. Coverage and adverse events surveillance are essential components of post-vaccination monitoring. Monitoring the impact of vaccination on HPV infection and disease in men raises some similar challenges to monitoring in females, such as the long time frame until cancer outcomes, and also different ones given that genital specimens suitable for monitoring HPV prevalence are not routinely collected for other diagnostic or screening purposes in males...
December 2016: Papillomavirus Research
https://www.readbyqxmd.com/read/29070638/hpv-knowledge-burden-and-genital-wart-location-among-heterosexually-identified-versus-homosexually-identified-men-who-have-sex-with-men-in-lima-peru-cross-sectional-results-from-a-cohort-study
#14
Jerome T Galea, Segundo R León, Jesús Peinado, Gino Calvo, Jonathan Zamora, Hugo Sánchez, Brandon J Brown
OBJECTIVES: The relationship between sexual practices, identity and role among Latino men who have sex with men (MSM) and HIV risk is the subject of ongoing investigation but less is known about how these aspects of sexuality relate to human papilloma-virus (HPV), an independent risk factor for HIV. This observational study investigated the relationship between HPV and sexual practices, identity and role as well as other sexually transmitted infection (STI)/HIV risk factors among HIV-negative heterosexually and homosexually identified Peruvian MSM...
October 24, 2017: BMJ Open
https://www.readbyqxmd.com/read/29055031/impact-of-gender-neutral-or-girls-only-vaccination-against-human-papillomavirus-results-of-a-community-randomized-clinical-trial-i
#15
Matti Lehtinen, Anna Söderlund-Strand, Simopekka Vänskä, Tapio Luostarinen, Tiina Eriksson, Kari Natunen, Dan Apter, Iacopo Baussano, Katja Harjula, Mari Hokkanen, Marjo Kuortti, Johanna Palmroth, Tiina Petäjä, Eero Pukkala, Sirpa Rekonen, Mari Siitari-Mattila, Heljä-Marja Surcel, Leena Tuomivaara, Jorma Paavonen, Joakim Dillner, Gary Dubin, Geoffrey Garnett
Human papillomavirus (HPV) vaccine is efficacious but the real-life effectiveness of gender-neutral and girls-only vaccination strategies is unknown. We report a community-randomized trial on the protective effectiveness [(PE) = vaccine efficacy (VE) + herd effect (HE)] of the two strategies among females in virtually HPV vaccination naïve population. We randomized 33 Finnish communities into Arm A) gender-neutral vaccination with AS04-adjuvanted HPV16/18 vaccine (11 communities), Arm B) HPV vaccination of girls and hepatitis B-virus (HBV) vaccination of boys (11 communities) or Arm C) gender-neutral HBV vaccination (11 communities)...
October 21, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29049330/the-prevalence-of-human-papillomavirus-in-oropharyngeal-cancer-in-a-new-zealand-population
#16
Rebecca Lucas-Roxburgh, Jackie Benschop, Bruce Lockett, Ursula van den Heever, Ruth Williams, Laryssa Howe
BACKGROUND: The incidence of oropharyngeal cancer (OPC) in New Zealand (NZ) has more than doubled over the last 14 years with 126 cases in 2010. Overseas studies have shown that human papillomavirus (HPV) plays a significant role in the development of these cancers. However, the role of HPV in OPC and the burden on the NZ health system is unclear. AIM: The aim of the study was to determine the prevalence and the genotypes of HPV associated with OPC in New Zealand...
2017: PloS One
https://www.readbyqxmd.com/read/29048728/cytokeratin7-expression-in-histologic-and-cytologic-specimens-of-cystic-neck-metastasis-from-hpv-positive-squamous-cell-carcinoma-of-the-tonsil-a-case-report
#17
Yong Kyun Cho, Seung Ju Lee, Jeong Joo Woo, Hyekyung Lee, Hojung Lee
The majority of cystic squamous cell carcinomas (SCCs) of the neck have been shown to be metastatic tumors from tonsillar SCCs associated with high-risk human papillomavirus (HR HPV). Recent studies have demonstrated cytokeratin (CK)7 involvement in the development of HPV positive SCC, but no report has been issued on its simultaneous expression in primary tonsillar and metastatic tumor with cystic change. We present a case of HPV positive tonsillar SCC of a 42-year-old male that initially manifested as a cystic neck mass expressing CK7, CK19, and p16 in primary and metastatic tumors...
October 19, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29042913/paediatric-virology-as-a-new-educational-initiative-an-interview-with-nobelist-professor-of-virology-harald-zur-hausen
#18
Ioannis N Mammas, Demetrios A Spandidos
Born in Gelsenkirchen-Buer in Germany on March 11th, 1936, Professor Harald zur Hausen, Emeritus Professor of Virology at the University of Freiburg and 2008 Nobel Prize Laureate in Physiology or Medicine for his discovery of human papillomavirus (HPV), which causes cervical cancer, believes that good knowledge of virological methods and diagnostic possibilities are an asset for all young paediatricians. Professor zur Hausen considers that the creation of an educational platform on Paediatric Virology is definitely very beneficial for young paediatricians, as this will greatly enhance their knowledge in the field of Virology...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29040176/hpv-awareness-and-vaccination-rates-in-college-aged-male-athletes
#19
Tonna McCutcheon, Gina Schaar, Alan Herline, Rachel Hayes
College-aged males are at high risk for human papillomavirus (HPV); however, vaccination rates remain low, suggesting minimal HPV knowledge. Therefore, an educational intervention was developed and implemented to determine if an increase in HPV knowledge, perceived HPV risk, intention and perceived self-efficacy to obtain the vaccine, and vaccination rates were observed.
November 16, 2017: Nurse Practitioner
https://www.readbyqxmd.com/read/29037233/cancer-incidence-in-germany-attributable-to-human-papillomavirus-in-2013
#20
Nina Buttmann-Schweiger, Yvonne Deleré, Stefanie J Klug, Klaus Kraywinkel
BACKGROUND: It is estimated that a total of 120,000 new cancer cases in men and in women in more developed countries could be avoided if exposure to HPV was prevented. We used the nationwide pool of German population-based cancer registry data to estimate the burden of HPV-attributable cancer in this population for the year 2013. METHODS: Incident cases of cervical cancer, squamous cell carcinoma of the anus, oropharynx (OP), as well as of the vulva, vagina and penis were classified as potentially HPV-associated and identified from the nationwide cancer registry data-pool...
October 16, 2017: BMC Cancer
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