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https://www.readbyqxmd.com/read/29327306/strengthening-the-case-for-gender-neutral-and-the-nonavalent-hpv-vaccine
#1
REVIEW
Justin M Hintze, James P O'Neill
PURPOSE: The purpose of this review is to highlight the benefits of gender-neutral and the nonavalent human papillomavirus vaccination. Human papillomavirus infection is the most commonly sexually transmitted disease and is known to cause several types of cancers, including cervical, vulvar, vaginal, penile, oropharyngeal, anal, and rectal. 5% of cancers every year are attributable to human papillomavirus infection, with cervical cancer the most common and oropharyngeal cancer estimated to surpass the incidence of cervical cancer by 2020...
January 11, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29325528/knowledge-attitudes-and-practices-regarding-cervical-cancer-and-screening-among-women-visiting-primary-health-care-centres-in-bahrain
#2
Ghufran Jassim, Alaaeddin Obeid, Huda A Al Nasheet
BACKGROUND: Cervical cancer is one of the most common cancers among women, with 80% of the cases occurring in developing countries. Cervical cancer is largely preventable by effective screening programs. This has not been possible with opportunistic screening and its low use in the Kingdom of Bahrain. The objective of this study was to explore the knowledge, attitudes, and practices of women attending primary care health centres for cervical cancer screening. METHODS: This was a cross-sectional study of 300 women attending primary health care centres in Bahrain...
January 11, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29322795/analysis-of-dna-methylation-and-microrna-expression-in-nut-nuclear-protein-in-testis-midline-carcinoma-of-the-sinonasal-tract-a-clinicopathological-immunohistochemical-and-molecular-genetic-study
#3
J Laco, H Kovarikova, M Chmelarova, H Vosmikova, K Sieglova, I Bubancova, P Dundr, K Nemejcova, J Michalek, P Celakovsky, R Mottl, I Sirak, M Vosmik, I Marek, T Geryk, J Mejzlik, J Satankova, A Ryska
The aim of this study was a detailed clinicopathological investigation of sinonasal NUT midline carcinoma (NMC), including analysis of DNA methylation and microRNA (miRNA) expression. Three (5%) cases of NMC were detected among 56 sinonasal carcinomas using immunohistochemical screening and confirmed by fluorescence in situ hybridization. The series comprised 2 males and 1 female, aged 46, 60, and 65 years. Two tumors arose in the nasal cavity and one in the maxillary sinus. The neoplasms were staged pT1, pT3, and pT4a (all cN0M0)...
2018: Neoplasma
https://www.readbyqxmd.com/read/29316825/on-surmounting-the-barriers-to-hpv-vaccination-we-can-do-better
#4
Aria C Attia, Judith Wolf, Ana Nuñez
The major impediment to increased HPV vaccination coverage in young males and females is lack of health care provider recommendation. Despite its efficacy in preventing cervical cancer, HPV vaccination in females (49.5%) and males (37.5%) ages 13 through 17 falls well below the Centers for Disease Control and Prevention's (CDC) Healthy People 2020 target of 80% coverage. Parents' willingness to vaccinate their child has been shown to be much higher when physicians share personal vaccination decisions for their own children as well as what other parents have done at that particular clinic...
January 10, 2018: Annals of Medicine
https://www.readbyqxmd.com/read/29310590/oral-human-papillomavirus-dna-detection-in-hiv-positive-men-prevalence-predictors-and-co-occurrence-at-anal-site
#5
Alessandra Vergori, Anna Rosa Garbuglia, Pierluca Piselli, Franca Del Nonno, Catia Sias, Federico Lupi, Daniele Lapa, Andrea Baiocchini, Claudia Cimaglia, Marco Gentile, Andrea Antinori, Maria Capobianchi, Adriana Ammassari
BACKGROUND: HIV-positive patients carry an increased risk of HPV infection and associated cancers. Therefore, prevalence and patterns of HPV infection at different anatomical sites, as well as theoretical protection of nonavalent vaccine should be investigated. Aim was to describe prevalence and predictors of oral HPV detection in HIV-positive men, with attention to nonavalent vaccine-targeted HPV types. Further, co-occurrence of HPV DNA at oral cavity and at anal site was assessed. METHODS: This cross-sectional, clinic-based study included 305 HIV-positive males (85...
January 8, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29280070/safety-of-human-papillomavirus-vaccines-an-updated-review
#6
REVIEW
Anastasia Phillips, Cyra Patel, Alexis Pillsbury, Julia Brotherton, Kristine Macartney
Human papillomavirus (HPV) vaccines are now included in immunisation programmes in 71 countries. Unfortunately, uptake has been impacted in some countries by reduced confidence in the safety of the HPV vaccine. In 2013, we published an extensive review demonstrating a reassuring safety profile for bivalent (2vHPV) and quadrivalent (4vHPV) vaccines. A nonavalent (9vHPV) vaccine is now available and HPV immunisation programmes have been extended to males in 11 countries. The aim of this updated narrative review was to examine the evidence on HPV vaccine safety, focusing on the 9vHPV vaccine, special populations and adverse events of special interest (AESI)...
December 26, 2017: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/29279282/parent-perceptions-of-dentists-role-in-hpv-vaccination
#7
Gabriela E Lazalde, Melissa B Gilkey, Melanie L Kornides, Annie-Laurie McRee
INTRODUCTION: Offering HPV vaccine in settings beyond the traditional medical home holds promise for increasing the currently low levels of coverage. As adolescents frequently visit dentists, dental practices may be one such alternative vaccination setting. This study assessed parent attitudes about the roles dental providers could play in HPV prevention, including vaccine provision. METHODS: In September 2016, we conducted an online survey using a national sample (n = 1209) of U...
December 23, 2017: Vaccine
https://www.readbyqxmd.com/read/29276162/hpv-unvaccinated-status-and-hpv-sexual-risk-behaviour-are-common-among-canadian-young-adult-women-and-men
#8
Melanie Zimmermann, Taylor Kohut, William A Fisher
OBJECTIVE: The current research focuses on sexual risk behaviour among young adult Canadians who have not been vaccinated against HPV. METHODS: Six hundred and forty-six Canadian university undergraduates completed a self-administered survey assessing HPV vaccination status and sexual risk behaviour. RESULTS: Five hundred and thirty-seven participants (154 men and 383 women aged 17-23) who met eligibility criteria were analyzed. 48.5% (n = 185) of female and 89...
December 21, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29244018/detection-of-novel-betapapillomaviruses-and-gammapapillomaviruses-in-eyebrow-hair-follicles-using-a-single-tube-hanging-droplet-pcr-assay-with-modified-pan-pv-codehop-primers
#9
Diego Chouhy, Boštjan J Kocjan, Jeannette P Staheli, Elisa M Bolatti, Lea Hošnjak, Martin Sagadin, Adriana A Giri, Timothy M Rose, Mario Poljak
A modified pan-PV consensus-degenerate hybrid oligonucleotide primer (CODEHOP) PCR was developed for generic and sensitive detection of a broad-spectrum of human papillomaviruses (HPVs) infecting the cutaneous epithelium. To test the analytical sensitivity of the assay we examined 149 eyebrow hair follicle specimens from immunocompetent male patients. HPV DNA was detected in 60 % (89/149) of analysed eyebrow samples with a total of 48 different HPV sequences, representing 21 previously described HPVs and 27 putative novel HPV types...
December 15, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/29243258/the-diagnostic-pathway-of-oropharyngeal-squamous-cell-carcinoma-in-a-large-u-s-healthcare-system
#10
Jason Gilde, Brian Song, Farzad Masroor, Jeanne A Darbinian, Miranda L Ritterman Weintraub, James Salazar, Eleanor Yang, Deepak Gurushanthaiah, Kevin H Wang
OBJECTIVE: To examine the current diagnostic pathway of oropharyngeal squamous cell carcinoma (OPSCC) and identify factors associated with time to diagnosis. METHODS: Retrospective cohort study of patients with OPSCC in an integrated healthcare system from January 1, 2013, to December 31, 2013. Patient demographics, tobacco and alcohol use, chief complaint, tumor stage, human papilloma virus (HPV) status, physician factors (diagnosis, antibiotic prescription, performance of endoscopic exam, biopsy), and time intervals were examined...
December 15, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29240623/improving-hpv-vaccination-rates-among-young-males-in-rural-areas-of-the-united-states
#11
Nicki Parton Vogel, Susan J Appel, Guyton Winker
Human papillomavirus (HPV) vaccination occurs more frequently among females ages 11 to 18 than their male counterparts. The purpose of this quality improvement project is to identify reasons why parents/guardians either choose or decline HPV immunization and increase rates of vaccination among males ages 11 to 18 in rural areas of the United States.
January 15, 2018: Nurse Practitioner
https://www.readbyqxmd.com/read/29235433/annual-prevalence-and-economic-burden-of-genital-warts-in-korea-health-insurance-review-and-assessment-hira-service-data-from-2007-to-2015
#12
Y J Park, J M Kim, B R Lee, T H Kim, E G Lee
This study evaluated the annual prevalence of anogenital warts (AGW) caused by human papillomavirus (HPV) and analysed the trend in annual per cent changes (APC) by using national claims data from the Health Insurance Review and Assessment of Korea, 2007-2015. We also estimated the socio-economic burden and co-morbidities of AGW. All analyses were performed based on data for primary A63.0, the specific diagnosis code for AGW. The socio-economic cost of AGW was calculated based on the direct medical cost, direct non-medical cost and indirect cost...
December 13, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/29208879/oncoe6-positivity-among-via-positive-suspected-cases-from-colposcopy-clinic-of-mymensingh-medical-college-hospital-mymensingh
#13
F Nahar, M A Hossain, S K Paul, M U Ahmed, S Khatun, N Akhter, G R Bhuiyan, S A Nasreen, S Roy, T K Barman, N Laskar, H Begum, S Abedin, N Haque, S Ahmed, N Kobayashi
Cervical cancer is a major world health problem for women. It is the fourth most leading cause of death in women around the world. High risk HPV DNA has been shown to be present in 99.7% of cervical cancers worldwide. Oncoprotein E6 and E7 play an important role in the development of cervical cancer which can be detected by OncoE6 cervical test. This Cross sectional observational study was performed to detect E6 Oncoprotein from cervical swab by OncoE6 cervical test. Following universal safety precautions a total of 47 endocervical swabs were collected from Colposcopy clinic of Obstetrics and Gynaecology department of Mymensingh Medical College Hospital (MMCH), Mymensingh, Bangladesh from January 2015 to December 2015...
October 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29206094/long-term-follow-up-and-outcome-in-patients-with-recurrent-respiratory-laryngeal-papillomatosis
#14
Eva Rye Rasmussen, Didde T Schnack, Andreas Schjellerup Jørkov, Anna Axelsson Raja, Caroline Holkmann Olsen, Preben Homøe
INTRODUCTION: Recurrent respiratory papillomatosis is characterized by wart-like lesions of the upper airway and is most frequently caused by human papillomavirus (HPV). The disease has significant impact on quality of life due to potential airway obstruction, dysphonia and the need for serial surgeries. The main objective of this study was to describe patient characteristics and long-term follow-up data in a Danish cohort with the disease. METHODS: The study was a longitudinal retrospective cohort-study using data from electronic medical records and a pathology database...
December 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/29191180/white-affluent-educated-parents-are-least-likely-to-choose-hpv-vaccination-for-their-children-a-cross-sectional-study-of-the-national-immunization-study-teen
#15
Echo L Warner, Qian Ding, Lisa M Pappas, Kevin Henry, Deanna Kepka
BACKGROUND: Human Papillomavirus (HPV) vaccination coverage is below national goals in the United States. Research is needed to inform strategically designed interventions that target sociodemographic groups with underutilization of HPV vaccination. METHODS: Secondary data analysis of the National Immunization Survey-Teen 2013 measured association of sociodemographic factors (e.g., ethnicity/race, insurance) with HPV vaccination among females and males ages 13-17 (N = 18,959)...
December 1, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/29190725/modelling-the-effects-of-quadrivalent-human-papillomavirus-hpv-vaccination-in-puerto-rico
#16
Ana Patricia Ortiz, Karen J Ortiz-Ortiz, Moraima Ríos, José Laborde, Amit Kulkarni, Matthew Pillsbury, Andreas Lauschke, Homero A Monsanto, Cecile Marques-Goyco
BACKGROUND: No study has estimated the potential impact of Human Papillomavirus (HPV) vaccination in Puerto Rico, a population with considerable burden of HPV-related morbidities. We evaluated the health and economic impacts of implementing a vaccination strategy for females and males in Puerto Rico, with the quadrivalent HPV (HPV4) vaccine, under different vaccination scenarios. METHODS: We adapted a mathematical model which estimates the direct and indirect health benefits and costs of HPV4 vaccination in a dynamic population...
2017: PloS One
https://www.readbyqxmd.com/read/29186268/quality-of-life-in-men-diagnosed-with-anogenital-warts
#17
Caio Cavassan de Camargo, Maria Paula Barbieri D'Elia, Helio Amante Miot
Anogenital warts are a worldwide public health problem. They consist of epithelial proliferations caused by HPV, whose transmission occurs mainly through sexual intercourse. In this study, we evaluated their impact on the quality of life of adult males. We interviewed 88 men in an outpatient clinic for sexually transmitted diseases at a Brazilian public institution, using the DLQI-BRA questionnaire. Most patients (81%) presented mild or no impairment of quality of life. The main dimensions affected were sex life, symptoms, and embarrassment...
May 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29184775/relationship-between-human-papillomavirus-and-penile-cancer-implications-for-prevention-and-treatment
#18
REVIEW
Laura C Kidd, Sharon Chaing, Juan Chipollini, Anna R Giuliano, Philippe E Spiess, Pranav Sharma
Penile cancer is a rare disease in the United States, but rates are increasing, causing concern. Several risk factors have been associated with the disease, including human papillomavirus (HPV) infection. Knowledge of HPV pathogenesis has led to the development of a vaccine, which has proven instrumental in reducing the incidence of female HPV-related cancers, but results in men have yet to be elucidated. Fortunately, rates of vaccination are up-trending in both males and females in the past several years. In addition, targeted therapies are the focus of several ongoing research efforts...
October 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29184774/updates-on-the-epidemiology-and-risk-factors-for-penile-cancer
#19
REVIEW
Antoin Douglawi, Timothy A Masterson
Penile cancer is a rare neoplasm representing less than 1% of all malignancies in the USA and Europe but is a significant public health hazard in the developing world. Male neonatal circumcision has been associated with a dramatic decrease in penile cancer rates with countries such as Israel, where circumcision is widely performed, having the lowest incidence in the world at <0.1% of malignancies. Many risk factors have been identified for penile cancer including phimosis, lack of circumcision, obesity, lichen sclerosis, chronic inflammation, smoking, UVA phototherapy, socioeconomic status, human papillomavirus (HPV) infection and immune compromised states...
October 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29182899/five-year-experience-of-the-treatment-of-squamous-cell-carcinoma-of-the-anus
#20
C A Leo, C Santorelli, J D Hodgkinson, O Bidovaneta, F Baldelli, F Cantarella, E Cavazzoni
OBJECTIVES: The best treatment of early stage anal squamous cell carcinoma (SCC) is under debated. Wide local excision (WLE) may be considered adequate for stage 1 anal margin cancer. This study demonstrates our experience in treatment of patients with SCC over 5 years. PATIENTS AND METHODS: We conducted a retrospective study of patients who had undergone anal screening or anal cancer surveillance between October 2010 and 2015 in our department. Each patient underwent anal Pap test, HPV test PCR HPV DNA and cytology by Thin Prep...
July 2017: Il Giornale di Chirurgia
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