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https://www.readbyqxmd.com/read/28317681/comparison-of-biometry-and-intraocular-lens-power-calculation-performed-by-a-new-optical-biometry-device-and-a-reference-biometer
#1
Bruna V Ventura, Marcelo C Ventura, Li Wang, Douglas D Koch, Mitchell P Weikert
PURPOSE: To compare biometry measurements and intraocular lens (IOL) power calculations obtained by a new optical A-scan interferometer biometer (Galilei G6) (new biometer) and a partial coherence interferometer biometer (IOLMaster 500) (reference biometer). SETTING: Private practice, Recife, Brazil. DESIGN: Retrospective comparative study. METHODS: Cataract patients who had biometric measurements with the new biometer and the reference biometer were included in the study...
January 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28295954/clinical-quantitative-susceptibility-mapping-qsm-biometal-imaging-and-its-emerging-roles-in-patient-care
#2
REVIEW
Yi Wang, Pascal Spincemaille, Zhe Liu, Alexey Dimov, Kofi Deh, Jianqi Li, Yan Zhang, Yihao Yao, Kelly M Gillen, Alan H Wilman, Ajay Gupta, Apostolos John Tsiouris, Ilhami Kovanlikaya, Gloria Chia-Yi Chiang, Jonathan W Weinsaft, Lawrence Tanenbaum, Weiwei Chen, Wenzhen Zhu, Shixin Chang, Min Lou, Brian H Kopell, Michael G Kaplitt, David Devos, Toshinori Hirai, Xuemei Huang, Yukunori Korogi, Alexander Shtilbans, Geon-Ho Jahng, Daniel Pelletier, Susan A Gauthier, David Pitt, Ashley I Bush, Gary M Brittenham, Martin R Prince
Quantitative susceptibility mapping (QSM) has enabled magnetic resonance imaging (MRI) of tissue magnetic susceptibility to advance from simple qualitative detection of hypointense blooming artifacts to precise quantitative measurement of spatial biodistributions. QSM technology may be regarded to be sufficiently developed and validated to warrant wide dissemination for clinical applications of imaging isotropic susceptibility, which is dominated by metals in tissue, including iron and calcium. These biometals are highly regulated as vital participants in normal cellular biochemistry, and their dysregulations are manifested in a variety of pathologic processes...
March 10, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28294406/does-transient-increase-in-axial-length-during-accommodation-attenuate-with-age
#3
Deborah S Laughton, Amy L Sheppard, Edward A H Mallen, Scott A Read, Leon N Davies
BACKGROUND: The aim was to profile transient accommodative axial length changes from early adulthood to advanced presbyopia and to determine whether any differences exist between the responses of myopic and emmetropic individuals. METHODS: Ocular biometry was measured by the LenStar biometer (Haag-Streit, Switzerland) in response to zero, 3.00 and 4.50 D accommodative stimuli in 35 emmetropes and 37 myopes, aged 18 to 60 years. All results were corrected to reduce errors arising from the increase in crystalline lens thickness with accommodation...
March 12, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28273542/microbial-attenuation-of-atrazine-in-agricultural-soils-biometer-assays-bacterial-taxonomic-diversity-and-catabolic-genes
#4
James F Douglass, Mark Radosevich, Olli H Tuovinen
The purpose of this study was to examine the potential biomineralization of atrazine and identification of atrazine-degrading bacteria in agricultural soils. Different atrazine application histories of soils impacted the kinetics of biomineralization but not the presence of catabolic genes of two atrazine degradative pathways (Trz and Atz). Biomineralization was based on the measurement of (14)CO2 from [U-ring-(14)C]-atrazine in surface soil (0-7 cm) samples incubated in biometers. Aerobic atrazine biomineralization rate constants (k) varied in the range of 0...
February 22, 2017: Chemosphere
https://www.readbyqxmd.com/read/28263734/comparison-of-axial-length-corneal-and-anterior-chamber-depth-measurements-of-two-recently-introduced-devices-to-a-known-biometer
#5
Mehdi Shajari, Carla Cremonese, Kerstin Petermann, Pankaj Singh, Michael Müller, Thomas Kohnen
PURPOSE: Evaluate agreement and repeatability of axial length (AL), corneal curvature and anterior chamber depth (ACD) measurements of two new devices, one using Scheimpflug technology combined with partial coherence interferometry (Pentacam AXL from Oculus, Germany) and one using swept-source OCT (IOL Master 700 from Zeiss, Germany) to a widely-used optical biometer (IOL Master 500 from Zeiss, Germany). DESIGN: Prospective, instrument reliability analysis METHODS: Setting: Department of Ophthalmology, Goethe-University, Frankfurt am Main, Germany Study population: 79 eyes of 79 patients Study Procedure: All eyes were measured with the IOL Master 500, the IOL Master 700 and with the Pentacam AXL...
March 2, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28260856/measurement-of-peripapillary-retinal-nerve-fiber-layer-thickness-and-macular-thickness-in-anisometropia-using-spectral-domain-optical-coherence-tomography-a-prospective-study
#6
Neha Singh, Jolly Rohatgi, Ved Prakash Gupta, Vinod Kumar
PURPOSE: To study whether there is a difference in central macular thickness (CMT) and peripapillary retinal nerve fiber layer (RNFL) thickness between the two eyes of individuals having anisometropia >1 diopter (D) using spectral domain optical coherence tomography (OCT). MATERIAL AND METHODS: One hundred and one subjects, 31 with myopic anisometropia, 28 with astigmatic anisometropia, and 42 with hypermetropic anisometropia, were enrolled in the study. After informed consent, detailed ophthalmological examination was performed for every patient including cycloplegic refraction, best corrected visual acuity, slit lamp, and fundus examination...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28259379/displaced-intracapsular-neck-of-femur-fractures-outcome-of-810-hydroxyapetite-coated-hac-uncemented-hemiarthroplasties
#7
S Z Nawaz, A J Keightley, A Desai, J Granville-Chapman, D Elliott, K Newman, A Khaleel
A Cochrane review influenced new NICE guidelines, which recommended surgeons: Offer cemented implants to patients undergoing surgery with arthroplasty. However our trust routinely uses HAC uncemented stem (Taperloc(®), Biomet) hemiarthroplasties. A review of a consecutive series of uncemented HAC stem hemiarthroplasties including measures such as intro-operative complications, mortality and revision surgery. Prospectively collected data between January 2008 and June 2014 was used, with medical record and radiographic reviews performed...
October 17, 2016: Injury
https://www.readbyqxmd.com/read/28249224/a-moderate-metal-binding-hydrazone-meets-the-criteria-for-a-bioinorganic-approach-towards-parkinson-s-disease-therapeutic-potential-blood-brain-barrier-crossing-evaluation-and-preliminary-toxicological-studies
#8
Daphne Schneider Cukierman, Ana Beatriz Pinheiro, Sergio L P Castiñeiras-Filho, Anastácia Sá P da Silva, Marco C Miotto, Anna De Falco, Thales de P Ribeiro, Silvia Maisonette, Alessandra L M C da Cunha, Rachel A Hauser-Davis, J Landeira-Fernandez, Ricardo Q Aucélio, Tiago F Outeiro, Marcos D Pereira, Claudio O Fernández, Nicolás A Rey
Alzheimer's and Parkinson's diseases share similar amyloidogenic mechanisms, in which metal ions might play an important role. In this last neuropathy, misfolding and aggregation of α-synuclein (α-Syn) are crucial pathological events. A moderate metal-binding compound, namely, 8-hydroxyquinoline-2-carboxaldehyde isonicotinoyl hydrazone (INHHQ), which was previously reported as a potential 'Metal-Protein Attenuating Compound' for Alzheimer's treatment, is well-tolerated by healthy Wistar rats and does not alter their major organ weights, as well as the tissues' reduced glutathione and biometal levels, at a concentration of 200mgkg(-1)...
February 22, 2017: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/28246095/explant-analysis-of-the-biomet-magnum-recap-metal-on-metal-hip-joint
#9
S C Scholes, B J Hunt, V M Richardson, D J Langton, E Smith, T J Joyce
OBJECTIVES: The high revision rates of the DePuy Articular Surface Replacement (ASR) and the DePuy ASR XL (the total hip arthroplasty (THA) version) have led to questions over the viability of metal-on-metal (MoM) hip joints. Some designs of MoM hip joint do, however, have reasonable mid-term performance when implanted in appropriate patients. Investigations into the reasons for implant failure are important to offer help with the choice of implants and direction for future implant designs...
February 2017: Bone & Joint Research
https://www.readbyqxmd.com/read/28231267/accuracy-of-optical-biometry-combined-with-placido-disc-corneal-topography-for-intraocular-lens-power-calculation
#10
Giacomo Savini, Kenneth J Hoffer, Piero Barboni, Nicole Balducci, Domenico Schiano-Lomoriello, Pietro Ducoli
PURPOSE: To investigate the accuracy of a new optical biometer for intraocular lens (IOL) power calculation in eyes undergoing cataract surgery. METHODS: Consecutive eyes of patients undergoing cataract surgery with the same IOL model were enrolled in a prospective cohort study. Axial length (AL) and corneal power were measured with an optical biometer based on optical low-coherence interferometry and Placido-disc corneal topography. IOL power was calculated with the Hoffer Q, Holladay 1 and SRK/T formulas...
2017: PloS One
https://www.readbyqxmd.com/read/28210651/analysis-of-platelet-rich-plasma-extraction-variations-in-platelet-and-blood-components-between-4-common-commercial-kits
#11
Jane Fitzpatrick, Max K Bulsara, Paul Robert McCrory, Martin D Richardson, Ming Hao Zheng
BACKGROUND: Platelet-rich plasma (PRP) has been extensively used as a treatment in tissue healing in tendinopathy, muscle injury, and osteoarthritis. However, there is variation in methods of extraction, and this produces different types of PRP. PURPOSE: To determine the composition of PRP obtained from 4 commercial separation kits, which would allow assessment of current classification systems used in cross-study comparisons. STUDY DESIGN: Controlled laboratory study...
January 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28199931/a-personalized-3d-printed-prosthetic-joint-replacement-for-the-human-temporomandibular-joint-from-implant-design-to-implantation
#12
David C Ackland, Dale Robinson, Michael Redhead, Peter Vee Sin Lee, Adrian Moskaljuk, George Dimitroulis
Personalized prosthetic joint replacements have important applications in cases of complex bone and joint conditions where the shape and size of off-the-shelf components may not be adequate. The objective of this study was to design, test and fabricate a personalized 3D-printed prosthesis for a patient requiring total joint replacement surgery of the temporomandibular joint (TMJ). The new 'Melbourne' prosthetic TMJ design featured a condylar component sized specifically to the patient and fixation screw positions that avoid potential intra-operative damage to the mandibular nerve...
February 6, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28194713/use-of-compressive-osseointegration-endoprostheses-for-massive-bone-loss-from-tumor-and-failed-arthroplasty-a-viable-option-in-the-upper-extremity
#13
Krista A Goulding, Adam Schwartz, Steven J Hattrup, R Lor Randall, Donald Lee, Damian M Rispoli, Daniel M Lerman, Christopher Beauchamp
BACKGROUND: Endoprostheses using principles of compressive osseointegration have shown good survivorship in several studies involving the lower extremity; however, no series to our knowledge have documented the use of this technology in the management of massive bone loss in the upper limb. QUESTIONS/PURPOSES: (1) What proportion of upper extremity implants using compressive osseointegration fixation principles achieved durable short-term fixation, and what were the modes of failure? (2) What surgical complications resulted from reconstruction using this technique? METHODS: A multiinstitutional retrospective review identified nine patients (five women; four men) who underwent 13 endoprosthetic replacements between 2003 and 2014 using compressive osseointegration (Compliant(®) Pre-stress Device [CPS]; Biomet Inc, Warsaw, IN, USA) in the upper extremity, including two proximal humeri, two humeral diaphyses, seven distal humeri, and two proximal ulna...
February 13, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28167878/commercial-separation-systems-designed-for-preparation-of-platelet-rich-plasma-yield-differences-in-cellular-composition
#14
Ryan M Degen, Johnathan A Bernard, Kristin S Oliver, Joshua S Dines
BACKGROUND: The role of platelet-rich plasma (PRP) in the treatment of sport-related injuries is unclear, largely due to the heterogeneity of clinical results. This may relate to compositional differences in PRP from different separation systems. QUESTIONS/PURPOSES: This study aims to compare the composition of PRP produced with five different commercially available systems, focusing on cellular concentrations and pH. METHODS: Seven donors (41 ± 12 years) provided blood for PRP preparation using five systems (Arthrex Angel, Emcyte Genesis CS, Arteriocyte Magellan, Harvest SmartPrep, and Biomet GPS III)...
February 2017: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
https://www.readbyqxmd.com/read/28167489/mechanical-properties-of-all-suture-anchors-for-rotator-cuff-repair
#15
N S Nagra, N Zargar, R D J Smith, A J Carr
OBJECTIVES: All-suture anchors are increasingly used in rotator cuff repair procedures. Potential benefits include decreased bone damage. However, there is limited published evidence for the relative strength of fixation for all-suture anchors compared with traditional anchors. MATERIALS AND METHODS: A total of four commercially available all-suture anchors, the 'Y-Knot' (ConMed), Q-FIX (Smith & Nephew), ICONIX (Stryker) and JuggerKnot (Zimmer Biomet) and a traditional anchor control TWINFIX Ultra PK Suture Anchor (Smith & Nephew) were tested in cadaveric human humeral head rotator cuff repair models (n = 24)...
February 2017: Bone & Joint Research
https://www.readbyqxmd.com/read/28137443/extra-articular-subcutaneous-inverted-king-post-truss-ligament-reconstruction-for-severe-swan-neck-deformity-snapping-finger
#16
X de Soras, P de Mourgues, P Pradel, J-P Urien, E Beaudoin
A swan neck deformity (SND) can be well tolerated for a long time, until the appearance of a disabling "snapping finger". In its most advanced condition, the other hand is needed to initiate finger flexion. We propose a technique of extra-articular, subcutaneous ligament reconstruction with an "inverted king post-truss" configuration use in roofs and to reinforce railway bridges. An artificial ligament (MaxBraid™ polyethylene surgical suture, 5 metric, Biomet) makes a figure of eight between transosseous tunnels in the proximal and middle phalanges, crossing over top of the A3 pulley...
February 2017: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/28130351/repeatability-and-agreement-of-ocular-biometry-measurements-aladdin-versus-lenstar
#17
Colm McAlinden, Rongrong Gao, Ayong Yu, Xiaorui Wang, Jing Yang, Ye Yu, Hao Chen, Qinmei Wang, Jinhai Huang
OBJECTIVE: To assess the repeatability and agreement between the Aladdin and Lenstar biometers. METHODS: Three consecutive measurements of the right eye of 102 subjects were acquired by the Aladdin (V.1.1.3) and the Lenstar (V.1.0.3), respectively, with a random order of which biometer to use first. Parameters compared included axial length (AL), anterior chamber depth (ACD), flat keratometry (Kf), steep keratometry (Ks), mean keratometry (Km), J0, J45 and white-to-white (WTW) distance...
January 27, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28119449/in-vivo-modelling-of-the-pathogenic-effect-of-copper-transporter-mutations-that-cause-menkes-and-wilson-disease-motor-neuropathy-and-susceptibility-to-alzheimer-s-disease
#18
Stephen W Mercer, Jianbin Wang, Richard Burke
Copper is an essential biometal and several inherited diseases are directly associated with a disruption to normal copper homeostasis. The best characterised are the copper deficiency and toxicity disorders Menkes and Wilson disease, caused by mutations in the p-Type Cu-ATPase genes ATP7A and ATP7B respectively. Missense mutations in the C-terminal portion of ATP7A have also been shown to cause Distal Motor Neuropathy while polymorphisms in ATP7B are associated with increased risk of Alzheimer's disease. We have generated a single, in vivo model for studying multiple pathogenic mutations in ATP7 proteins, using Drosophila melanogaster, which has a single orthologue of ATP7A and ATP7B...
January 24, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28096459/zinc-and-copper-differentially-modulate-amyloid-precursor-protein-processing-by-%C3%AE-secretase-and-amyloid-%C3%AE-peptide-production
#19
Hermeto Gerber, Fang Wu, Mitko Dimitrov, Guillermo M Garcia Osuna, Patrick C Fraering
Recent evidence suggests involvement of biometal homeostasis in the pathological mechanisms in Alzheimer's disease (AD). For example, increased intracellular copper or zinc has been linked to a reduction in secreted levels of the AD-causing amyloid-β peptide (Aβ). However, little is known about whether these biometals modulate the generation of Aβ. In the present study, we demonstrate in both cell-free and cell-based assays that zinc and copper regulate Aβ production by distinct molecular mechanisms affecting the processing by γ-secretase of its Aβ precursor protein substrate APP-C99...
January 17, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28072898/three-year-results-with-a-ringless-third-generation-porous-plasma-sprayed-acetabular-component-in-primary-total-hip-arthroplasty
#20
Keith R Berend, Joanne B Adams, Michael J Morris, Adolph V Lombardi
INTRODUCTION: We previously reported promising early results in patients undergoing primary total hip arthroplasty (THA) with a third-generation cementless acetabular system that has a porous plasma-sprayed coating on a titanium alloy substrate shell, a ringless barb and groove locking mechanism, and a vitamin E-infused highly crosslinked polyethylene insert. The purpose of this study was to examine the outcomes and need for revision in a subset of patients previously reviewed who now have potential for three-year follow-up...
January 10, 2017: Surgical Technology International
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