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gonadotropin realeasing hormone

Wang Xiao-xia, Kang Jia-li, Shao Xue-fei, Yu Jia, Deng Ling-hong
AIM: To investigate the effect of Gonadotropin-realeasing hormone agonist (GnRHa) on apoptosis and the release of vascular endothelial growth factor (VEGF) in the in vitro eutopic endometrial cell of adenomyosis. METHODS: Biopsy specimens of eutopic endometrium obtained from 32 women with adenomyosis and 20 normal womenwere studied. Cells were cultured with GnRHa for 24 h, 48 h and 72 h in the concentration of 10-7 mol/L and 105 mol/L. Apoptotic ratio was detected by terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) and flow cytometry before and after using GnRHa...
January 2012: Xi Bao Yu Fen Zi Mian Yi Xue za Zhi, Chinese Journal of Cellular and Molecular Immunology
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