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https://www.readbyqxmd.com/read/29912035/bone-marrow-derived-cd8-t-cells-from-pediatric-leukemia-patients-express-pd1-and-expand-ex-vivo-following-induction-chemotherapy
#1
Katie Palen, Monica Thakar, Bryon D Johnson, Jill A Gershan
Adoptive cell therapy (ACT) of chimeric antigen receptor T cells has demonstrated remarkable success for the treatment of pediatric B-cell leukemia. For patients who are not candidates for chimeric antigen receptor T-cell therapy, ACT using tumor antigen-experienced polyclonal T cells may be a treatment option. Since leukemic blasts reside in the bone marrow and bone marrow is a preferred site for homeostatic proliferation of cytotoxic memory CD8 T cells, we hypothesized that bone marrow would be a source of activated T cells...
June 14, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29904533/using-the-tools-of-informal-science-education-to-connect-science-and-the-public
#2
April Killikelly
Traditional modes of communication within the scientific community, including presentation of data at conferences and in peer-reviewed publications, use technical jargon that limits public engagement. While altering word choice is an important method for increasing public engagement, the data itself may not be enough. For example, communicating the lack of evidence that vaccines cause autism did not convince many reluctant parents to vaccinate their kids (Nyhan, Reifler, Richey, Freed, Pediatrics 133:e835-e842, 2014)...
2018: Journal of Microbiology & Biology Education: JMBE
https://www.readbyqxmd.com/read/29901549/a-bibliometric-analysis-of-clinical-and-translational-research-in-pediatric-gastroenterology-from-1970-to-2017
#3
Melanie H Schwimmer, Mary Catherine Sawh, Karen M Heskett, Nidhi P Goyal, Kimberly P Newton, Jeffrey B Schwimmer
OBJECTIVES: Pediatric gastroenterology is a clinical and research discipline principally developed over the past 50 years. Bibliometric methods provide quantitative analysis and identify research trends. Study aims were to characterize the growth and trends in pediatric gastroenterology clinical and translational research using citation analysis. METHODS: Using citations analysis software, a search strategy specific for pediatric gastroenterology was implemented for the years 1970-2017...
June 12, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29886602/-consensus-statement-on-diagnosis-and-management-of-patients-with-turner-syndrome-in-children
#4
(no author information available yet)
No abstract text is available yet for this article.
June 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29877012/interventions-using-pediatric-diabetes-registry-data-for-quality-improvement-a-systematic-review
#5
Erica Burry, Noah Ivers, Farid H Mahmud, Rayzel Shulman
BACKGROUND: Diabetes registries contain vast amounts of data that can be used for quality improvement (QI) and are foundational elements of learning health systems; infrastructure to share data, create knowledge rapidly and inform decisions to improve health outcomes. QI interventions using adult diabetes registries are associated with improved glycemic control, complication screening rates, and reduced hospitalizations; pediatric data are limited. OBJECTIVE: To evaluate the effects of QI strategies that use pediatric diabetes registry data on care processes, organization of care, and patient outcomes...
June 7, 2018: Pediatric Diabetes
https://www.readbyqxmd.com/read/29869707/-reporting-ethics-board-approval-in-german-medical-theses-and-journals
#6
REVIEW
Michael Zenz, Julia Zenz, Maximilian Grieger
Since 1975, the Declaration of Helsinki of the World Medical Association (WMA) has clearly required ethics committee approval for research into humans. Nevertheless, this Declaration is violated quite often. As many English-language publications have addressed the theme of ethics board approval in theses and other published works, it is now to be investigated in Germany for the first time.From 2013 to 2014, a total of 1,482 medical theses at four selected universities in addition to three German-language scientific journals were reviewed...
June 5, 2018: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/29864098/activity-and-exercise-intolerance-after-concussion-identification-and-management-of-postural-orthostatic-tachycardia-syndrome
#7
Nicole A Miranda, Jeffrey R Boris, Kristen M Kouvel, Lauren Stiles
BACKGROUND AND PURPOSE: Postural orthostatic tachycardia syndrome (POTS) is increasingly recognized as a complication affecting recovery from concussion. Individuals with POTS demonstrate refractory dizziness, lightheadedness, cognitive dysfunction, fatigue, headache, chronic pain, nausea and gastrointestinal dysmotility, activity and exercise intolerance, syncope, and tachycardia. Subtypes of POTS may include hypovolemia, hyperadrenergic states, autonomic neuropathy, and underlying autoimmunity, which may variably impact response to rehabilitation in varying ways...
June 1, 2018: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/29847541/physicians-risk-tolerance-and-head-computed-tomography-use-for-pediatric-patients-with-minor-head-injury
#8
Chi-Yung Cheng, Hsiu-Yung Pan, Chao-Jui Li, Yi-Chuan Chen, Chien-Chih Chen, Yi-Syun Huang, Fu-Jen Cheng
OBJECTIVES: Traumatic brain injury is the leading cause of death and disability in children worldwide. The objective of this study was to determine the association between physician risk tolerance and head computed tomography (CT) use in patients with minor head injury (MHI) in the emergency department (ED). METHODS: We retrospectively analyzed pediatric patients (<17 years old) with MHI in the ED and then administered 2 questionnaires (a risk-taking subscale [RTS] of the Jackson Personality Inventory and a malpractice fear scale [MFS]) to attending physicians who had evaluated these patients and made decisions regarding head CT use...
May 25, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29846367/bibliometric-characteristics-of-predatory-journals-in-pediatrics
#9
Peter Kokol, Jernej Završnik, Bojan Žlahtič, Helena Blažun Vošner
No abstract text is available yet for this article.
May 30, 2018: Pediatric Research
https://www.readbyqxmd.com/read/29806188/pediatric-pulmonology-year-in-review-2017-part-3
#10
REVIEW
Clement L Ren, Heather N Muston, Ozge Yilmaz, Terry L Noah
Pediatric Pulmonology publishes original research, reviews, and case reports related to a wide range of children's respiratory disorders. We here summarize the past year's publications in our major topic areas, in the context of selected literature in these areas from other journals relevant to our discipline. This review (Part 3 of a 5-part series) covers selected articles on asthma, physiology/lung function testing, and respiratory infections.
May 27, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29801548/50-years-ago-in-the-journal-of-pediatrics-concentration-of-ampicillin-in-exudate-from-acute-otitis-media
#11
Philip Toltzis
No abstract text is available yet for this article.
June 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29801541/50-years-ago-in-the-journal-of-pediatrics-birth-weight-gestational-age-and-sex-as-determining-factors-in-the-incidence-of-respiratory-distress-syndrome-of-prematurely-born-infants
#12
https://www.readbyqxmd.com/read/29801540/50-years-ago-in-the-journal-of-pediatrics-central-nervous-system-damage-and-hypoglycemia
#13
Jill Chang
No abstract text is available yet for this article.
June 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29801537/50-years-ago-in-the-journal-of-pediatrics-the-hemolytic-uremic-syndrome-renal-status-of-76-patients-at-long-term-follow-up
#14
Joseph L Alge, Scott E Wenderfer
No abstract text is available yet for this article.
June 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29801536/50-years-ago-in-the-journal-of-pediatrics-methotrexate-induced-congenital-malformations-with-a-review-of-the-literature
#15
Philip J Hashkes
No abstract text is available yet for this article.
June 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29800385/editorial-new-instructions-for-single-subject-research-in-the-journal-of-pediatric-psychology
#16
Bryan T Karazsia
No abstract text is available yet for this article.
May 24, 2018: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/29797578/respiratory-muscle-training-for-cystic-fibrosis
#17
REVIEW
Nathan Hilton, Arturo Solis-Moya
BACKGROUND: Cystic fibrosis is the most common autosomal recessive disease in white populations, and causes respiratory dysfunction in the majority of individuals. Numerous types of respiratory muscle training to improve respiratory function and health-related quality of life in people with cystic fibrosis have been reported in the literature. Hence a systematic review of the literature is needed to establish the effectiveness of respiratory muscle training (either inspiratory or expiratory muscle training) on clinical outcomes in cystic fibrosis...
May 24, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29790678/pediatric-pulmonology-year-in-review-2017-part-1
#18
William A Gower, David J Birnkrant, Jane B Black, Thomas Nicolai, Terry L Noah
Pediatric Pulmonology publishes original research, case reports and review articles on topics related to a wide range of children's respiratory disorders. In this article (Part 1 of a series), we summarize the past year's publications in our major topic areas, as well as selected literature in these areas from other journals. In Part 1, we review selected articles on diagnostic testing/endoscopy, respiratory complications of neuromuscular disorders, and rare lung diseases.
May 23, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29783816/-consensus-on-extracorporeal-membrane-oxygenation-support-for-neonatal-respiratory-failure
#19
(no author information available yet)
No abstract text is available yet for this article.
May 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29782406/population-pharmacokinetics-and-pharmacodynamics-of-dexmedetomidine-in-children-undergoing-ambulatory-surgery
#20
María-Gabriela Pérez-Guillé, Alejandra Toledo-López, Liliana Rivera-Espinosa, Radames Alemon-Medina, Chiharu Murata, Ismael Lares-Asseff, Juan Luis Chávez-Pacheco, Josefina Gómez-Garduño, Ana-Lilia Zamora Gutiérrez, Claudia Orozco-Galicia, Karina Ramírez-Morales, Gustavo Lugo-Goytia
BACKGROUND: Dexmedetomidine (DEX) is an α-2 adrenergic agonist with sedative and analgesic properties. Although not approved for pediatric use by the Food and Drug Administration, DEX is increasingly used in pediatric anesthesia and critical care. However, very limited information is available regarding the pharmacokinetics of DEX in children. The aim of this study was to investigate DEX pharmacokinetics and pharmacodynamics (PK-PD) in Mexican children 2-18 years of age who were undergoing outpatient surgical procedures...
May 17, 2018: Anesthesia and Analgesia
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