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https://www.readbyqxmd.com/read/28295041/exome-sequencing-identifies-primary-carnitine-deficiency-in-a-family-with-cardiomyopathy-and-sudden-death
#1
Najim Lahrouchi, Elisabeth M Lodder, Maria Mansouri, Rafik Tadros, Layla Zniber, Najlae Adadi, Sally-Ann B Clur, Karin Y van Spaendonck-Zwarts, Alex V Postma, Abdelaziz Sefiani, Ilham Ratbi, Connie R Bezzina
Pediatric cardiomyopathy is a rare but severe disease with high morbidity and mortality. The causes are poorly understood and can only be established in one-third of cases. Recent advances in genetic technologies, specifically next-generation sequencing, now allow for the detection of genetic causes of cardiomyopathy in a systematic and unbiased manner. This is particularly important given the large clinical variability among pediatric cardiomyopathy patients and the large number of genes (>100) implicated in the disorder...
March 15, 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/28288079/evidence-based-pediatric-orthopaedics-how-safe-is-safe
#2
G Alexander Augustithis, Hannah Margaret Ensor, James S Huntley
BACKGROUND: The aim of minimizing the risks of complications and adverse events is at the center of surgical practice.This study aimed to assess the evidence on which pediatric orthopaedic surgical procedures are described as "safe." In particular, the objective was to ascertain the proportion of studies describing a procedure as "safe," which achieved a 95% upper limit confidence interval of risk of 5% or less for major adverse events. METHOD: A primary search of Journal of Paediatric Orthopaedics 2009 to 2014 for the single term "safe" returned 71 papers appropriate for analysis...
March 10, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28285865/application-of-the-strengthening-the-reporting-of-observational-studies-in-epidemiology-strobe-statement-to-publications-on-endoscopic-treatment-for-vesicoureteral-reflux
#3
M K Farrugia, A J Kirsch
OBJECTIVE: Following an increasing number of submissions on endoscopic treatment of vesicoureteral reflux (VUR), the Journal of Pediatric Urology sought to establish a quality guideline that would enable reviewers to select the best papers for publication in the journal. The "Strengthening the Reporting of Observational Studies in Epidemiology" (STROBE) Statement, established in 2007, is a 22-item checklist designed to assist with clear reporting of observational studies. This checklist includes a description of methodological items and instructions on how to use them to transparently report observational studies...
February 17, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28285283/factors-affecting-subsequent-full-text-publication-of-papers-presented-at-the-annual-conference-of-the-indian-academy-of-pediatrics
#4
Sumaira Khalil, Devendra Mishra, Ruchi Mishra, Shalu Gupta
OBJECTIVE: To study the factors associated with the subsequent (over next 9 years) full-text publication of papers presented at the 44th National Conference of Indian Academy of Pediatrics (PEDICON), 2007. METHODS: All papers presented at PEDICON 2007 were searched for subsequent full-text publication over the next 9 years in English-language journals by an internet-based search. The published papers were compared with the conference-abstracts. Results: 74 (16%) of the 450 abstracts presented were subsequently published; 61 (82...
February 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/28281283/artificial-organs-2016-a-year-in-review
#5
REVIEW
Angela T Hadsell, Paul S Malchesky
In this Editor's Review, articles published in 2016 are organized by category and briefly summarized. We aim to provide a brief reflection of the currently available worldwide knowledge that is intended to advance and better human life while providing insight for continued application of technologies and methods of organ Replacement, Recovery, and Regeneration. As the official journal of The International Federation for Artificial Organs, The International Faculty for Artificial Organs, the International Society for Mechanical Circulatory Support, the International Society for Pediatric Mechanical Cardiopulmonary Support, and the Vienna International Workshop on Functional Electrical Stimulation, Artificial Organs continues in the original mission of its founders "to foster communications in the field of artificial organs on an international level...
March 2017: Artificial Organs
https://www.readbyqxmd.com/read/28277550/participation-of-iranian-cerebral-palsy-children-in-life-areas-a-systematic-review-article
#6
REVIEW
Marzieh Pashmdarfard, Malek Amini, Afsoon Hassani Mehraban
OBJECTIVE: Cerebral palsy (CP) is the most common cause of chronic disability that restricts participation in areas of occupations for children. The main aim of rehabilitation is enhancement of their clients for participation in occupations. The aim of this study was to overview of the factors influencing the participations of children with CP in Iran. MATERIALS & METHODS: A systematic, evidence-based process (Duffy 2005) was used. For data gathering electronic databases including Google scholar and Iranian and foreigner famous journals in the fields of pediatrics, were used...
2017: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/28273196/family-report-compared-to-clinician-documented-diagnoses-for-psychiatric-conditions-among-hospitalized-children
#7
Stephanie K Doupnik, Chris Feudtner, Steven C Marcus
BACKGROUND: Psychiatric comorbidity is common in pediatric medical and surgical hospitalizations and is associated with worse hospital outcomes. Integrating medical or surgical and psychiatric hospital care depends on accurate estimates of which hospitalized children have psychiatric comorbidity. OBJECTIVE: We conducted a study to determine agreement of family report (FR) and clinician documentation (CD) identification of psychiatric diagnoses in hospitalized children...
February 28, 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/28251572/translational-research-in-pediatric-pulmonary-disease-2017
#8
Bruce K Rubin
As readers of this journal know, translational research is the application of basic science findings to improve clinical care; a process that was once called "bench-to-bedside" research. In my field of pediatric pulmonary disease, the rapid advancement of basic science understanding into improved clinical care has been, to use an appropriate term, breathtaking. In this perspective article, I will describe a few of these advances, as they relate to specific pulmonary diseases.
December 2017: Clinical and Translational Medicine
https://www.readbyqxmd.com/read/28240622/oxandrolone-coadministration-does-not-alter-plasma-propranolol-concentrations-in-severely-burned-pediatric-patients
#9
Ashley N Guillory, David N Herndon, Michael B Silva, Clark R Andersen, Oscar E Suman, Celeste C Finnerty
The systemic impact of severe burn injury results in a variety of disorders that require therapeutic intervention. Propranolol, a nonselective β1, β2-adrenergic receptor antagonist, reduces resting heart rate and cardiac work caused by elevated circulating catecholamines. Oxandrolone, a testosterone mimetic, promotes protein synthesis and anabolism to counter muscle wasting. Coadministration of these drugs is expected to synergistically improve patient outcomes. Testosterone administration is known to alter β-adrenergic receptor-mediated signaling...
February 23, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28237444/50-years-ago-in-the-journal-of-pediatrics-diencephalic-syndromes-of-infancy-report-of-3-children-with-emaciation-syndrome-and-disproportionately-large-hands-and-feet
#10
Emily B Heikamp, Susan M Blaney
No abstract text is available yet for this article.
March 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28228565/a-dedicated-scholarly-research-program-in-an-adult-and-pediatric-neurology-residency-program
#11
Matthew S Robbins, Sheryl R Haut, Richard B Lipton, Mark J Milstein, Lenore C Ocava, Karen Ballaban-Gil, Solomon L Moshé, Mark F Mehler
OBJECTIVE: To describe and assess the effectiveness of a formal scholarly activity program for a highly integrated adult and pediatric neurology residency program. METHODS: Starting in 2011, all graduating residents were required to complete at least one form of scholarly activity broadly defined to include peer-reviewed publications or presentations at scientific meetings of formally mentored projects. The scholarly activity program was administered by the associate residency training director and included an expanded journal club, guided mentorship, a required grand rounds platform presentation, and annual awards for the most scholarly and seminal research findings...
February 22, 2017: Neurology
https://www.readbyqxmd.com/read/28224100/early-infant-male-circumcision-systematic-review-risk-benefit-analysis-and-progress-in-policy
#12
Brian J Morris, Sean E Kennedy, Alex D Wodak, Adrian Mindel, David Golovsky, Leslie Schrieber, Eugenie R Lumbers, David J Handelsman, John B Ziegler
AIM: To determine whether recent evidence-based United States policies on male circumcision (MC) apply to comparable Anglophone countries, Australia and New Zealand. METHODS: Articles in 2005 through 2015 were retrieved from PubMed using the keyword "circumcision" together with 36 relevant subtopics. A further PubMed search was performed for articles published in 2016. Searches of the EMBASE and Cochrane databases did not yield additional citable articles. Articles were assessed for quality and those rated 2+ and above according to the Scottish Intercollegiate Grading System were studied further...
February 8, 2017: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/28221185/antipyretic-therapy-in-critically-ill-septic-patients-a-systematic-review-and-meta-analysis
#13
Anne M Drewry, Enyo A Ablordeppey, Ellen T Murray, Carolyn R T Stoll, Sonya R Izadi, Catherine M Dalton, Angela C Hardi, Susan A Fowler, Brian M Fuller, Graham A Colditz
OBJECTIVE: This meta-analysis aimed to examine the impact of antipyretic therapy on mortality in critically ill septic adults. DATA SOURCES: Literature searches were implemented in Ovid Medline, Embase, Scopus, Cumulative Index of Nursing and Allied Health Literature, Cochrane Central Register of Controlled Trials, NHS Economic Evaluation Database, and ClinicalTrials.gov through February 2016. STUDY SELECTION: Inclusion criteria were observational or randomized studies of septic patients, evaluation of antipyretic treatment, mortality reported, and English-language version available...
February 17, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28212419/evaluating-the-lexico-grammatical-differences-in-the-writing-of-native-and-non-native-speakers-of-english-in-peer-reviewed-medical-journals-in-the-field-of-pediatric-oncology-creation-of-the-genuine-index-scoring-system
#14
Alberto Alexander Gayle, Motomu Shimaoka
INTRODUCTION: The predominance of English in scientific research has created hurdles for "non-native speakers" of English. Here we present a novel application of native language identification (NLI) for the assessment of medical-scientific writing. For this purpose, we created a novel classification system whereby scoring would be based solely on text features found to be distinctive among native English speakers (NS) within a given context. We dubbed this the "Genuine Index" (GI). METHODOLOGY: This methodology was validated using a small set of journals in the field of pediatric oncology...
2017: PloS One
https://www.readbyqxmd.com/read/28207982/understanding-ethical-issues-of-research-participation-from-the-perspective-of-participating-children-and-adolescents-a-systematic-review
#15
Stacey Crane, Marion E Broome
BACKGROUND: The past 20 years have seen distinct shifts in the way the participation of children and adolescents in research is viewed. This has been emphasized by the growing pediatric research enterprise. Additional information on children's and adolescents' experiences during research participation is needed to better inform researchers on the ethical conduct of research with this vulnerable population. AIMS: The objective of this analysis was to examine ethical issues in research with children and adolescents from their perspective as participants, including: assent, parental consent, risk perception, impact of research participation, and incentives...
February 16, 2017: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/28182805/assessment-of-readability-understandability-and-completeness-of-pediatric-hospital-medicine-discharge-instructions
#16
Ndidi I Unaka, Angela Statile, Julianne Haney, Andrew F Beck, Patrick W Brady, Karen E Jerardi
The average American adult reads at an 8th-grade level. Discharge instructions written above this level might increase the risk of adverse outcomes for children as they transition from hospital to home. We conducted a cross-sectional study at a large urban academic children's hospital to describe readability levels, understandability scores, and completeness of written instructions given to families at hospital discharge. Two hundred charts for patients discharged from the hospital medicine service were randomly selected for review...
February 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/28165536/journal-of-pediatric-psychology-editorial-board
#17
(no author information available yet)
No abstract text is available yet for this article.
January 1, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/28165534/journal-of-pediatric-psychology-volume-42-number-1-january-february-2017
#18
(no author information available yet)
No abstract text is available yet for this article.
January 1, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/28165530/journal-of-pediatric-psychology-front-cover
#19
(no author information available yet)
No abstract text is available yet for this article.
January 1, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/28162193/-the-quality-of-epidemiological-research-on-pediatric-refractive-error-and-amblyopia-in-china-needs-to-be-improved
#20
M G He
Over the past decade, great progress has been made in the clinical and epidemiological studies on refractive error and amblyopia in children with research findings published in international peer reviewed journals. This article reviews some of the essential publications so that the research findings could be learnt extensively, understood critically and objectively, and applied effectively to clinical practice. We aim to address the current limitations and shed light on clinical practice. (Chin J Ophthalmol, 2017, 53: 3-6)...
January 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
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