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Descartes

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https://www.readbyqxmd.com/read/28808076/influence-of-the-duration-of-penicillin-prescriptions-on-outcomes-for-acute-sore-throat-in-adults-the-descarte-prospective-cohort-study-in-uk-general-practice
#1
Michael Moore, Beth Stuart, Fd Richard Hobbs, Chris C Butler, Alastair D Hay, John Campbell, Brendan C Delaney, Sue Broomfield, Paula Barratt, Kerenza Hood, Hazel Everitt, Mark Mullee, Ian Williamson, David Mant, Paul Little
BACKGROUND: Guidelines recommend 10-day treatment courses for acute sore throat, but shorter courses may be used in practice. AIM: To determine whether antibiotic duration predicts adverse outcome of acute sore throat in adults in routine care. DESIGN AND SETTING: A secondary analysis of the DESCARTE (Decision rule for the Symptoms and Complications of Acute Red Throat in Everyday practice) prospective cohort study of 12 829 adults presenting in UK general practice with acute sore throat...
August 14, 2017: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/28808075/symptom-response-to-antibiotic-prescribing-strategies-in-acute-sore-throat-in-adults-the-descarte-prospective-cohort-study-in-uk-general-practice
#2
Michael Moore, Beth Stuart, Fd Richard Hobbs, Chris C Butler, Alastair D Hay, John Campbell, Brendan C Delaney, Sue Broomfield, Paula Barratt, Kerenza Hood, Hazel A Everitt, Mark Mullee, Ian Williamson, David Mant, Paul Little
BACKGROUND: A delayed or 'just in case' prescription has been identified as having potential to reduce antibiotic use in sore throat. AIM: To determine the symptomatic outcome of acute sore throat in adults according to antibiotic prescription strategy in routine care. DESIGN AND SETTING: A secondary analysis of the DESCARTE (Decision rule for the Symptoms and Complications of Acute Red Throat in Everyday practice) prospective cohort study comprising adults aged ≥16 years presenting with acute sore throat (≤2 weeks' duration) managed with treatment as usual in primary care in the UK...
August 14, 2017: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/28757486/the-picture-multiple-figuring-thinking-and-knowing-in-descartes-s-i-essais-i-1637
#3
Melissa Lo
Throughout his Essais (1637), Descartes appropriated the visual language of practical mathematics in order to forge a new natural philosophy. This article argues that by grafting geometric line onto descriptive figure, the philosopher and his illustrator, Frans van Schooten Jr., underscored doubts about a natural philosophy based on qualities, all the while situating his new epistemology in the 17th-century present and exercising a deep attention to the differences between nature seen, nature pictured, and nature understood...
2017: Journal of the History of Ideas
https://www.readbyqxmd.com/read/28662154/how-minimal-executive-feedback-influences-creative-idea-generation
#4
Hicham Ezzat, Anaëlle Camarda, Mathieu Cassotti, Marine Agogué, Olivier Houdé, Benoît Weil, Pascal Le Masson
The fixation effect is known as one of the most dominant of the cognitive biases against creativity and limits individuals' creative capacities in contexts of idea generation. Numerous techniques and tools have been established to help overcome these cognitive biases in various disciplines ranging from neuroscience to design sciences. Several works in the developmental cognitive sciences have discussed the importance of inhibitory control and have argued that individuals must first inhibit the spontaneous ideas that come to their mind so that they can generate creative solutions to problems...
2017: PloS One
https://www.readbyqxmd.com/read/28614439/residual-volume-in-vials-of-antibiotics-used-in-pediatrics
#5
Caroline Magna Pessoa Chaves, Carolina Martins Bezerra, Francisca Elisângela Teixeira Lima, Maria Vera Lúcia Moreira Leitão Cardoso, Said Gonçalves da Cruz Fonseca, Viviane Martins da Silva
OBJECTIVE: Quantifying residual volume contained in vials of antibiotics used in pediatrics. METHOD: This is an experiment involving samples from vials of antibiotics used in a pediatric hospital. Residual volume was identified by calculating the difference in weight measurement before and after the vials were washed. Evaluation of the residual volume difference in the vials was determined by the Wilcoxon non-parametric test for a sample and established at a significance level of 5%...
June 12, 2017: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/28612510/empowering-trainees-to-promote-professionalism
#6
Lita Aeder, Lisa Altshuler, Elizabeth Kachur, Ingrid Walker-Descartes
BACKGROUND: Unprofessional behaviour can interfere with patient care. Empowering trainees to address each other's unprofessional behaviour can help address a larger number of incidents that may not be witnessed by supervisors, as well as promote a culture of professionalism in a teaching programme. The goal of the study was to teach trainees to effectively address observed unprofessional behaviour and to assess the impact of this exercise on the percentage of cases directly addressed, reported or ignored 6-12 months after the initial training...
June 14, 2017: Clinical Teacher
https://www.readbyqxmd.com/read/28566145/the-brain-of-ren%C3%A3-descartes-1650-a-neuro-anatomical-analysis
#7
Charlier Philippe, Huynh-Charlier Isabelle, Froesch Philippe, Shorto Russell, Benmoussa Nadia, Froment Alain, Grimaud-Hervé Dominique, Deo Saudamini, Augias Anaïs, Albessard Lou, Balzeau Antoine
The skull of René Descartes is held in the National Museum of Natural History since the 19th c. Up to date, only anthropological examinations were carried out, focusing on the cranial capacity and phrenological interpretation of the skull morphology. Using CT-scan based 3D technology, a reconstruction of the endocast was performed, allowing for its first complete description and inter-disciplinary analysis: assessment of metrical and non-metrical features, retrospective diagnosis of anatomical anomalies, and confrontation with neuro-psychological abilities of this well-identified individual...
July 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28562812/insulin-therapy-waste-produced-in-the-households-of-people-with-diabetes-monitored-in-primary-care
#8
Gilmara Holanda da Cunha, Raiza Verônica Almeida Barbosa, Marina Soares Monteiro Fontenele, Maria Amanda Correia Lima, Katia Barbosa Franco, Francisco Vagnaldo Fechine
Objective: To analyze the insulin therapy waste disposal produced in the households of people with diabetes mellitus (DM). Method: Cross-sectional study with 105 Primary Care patients. Socio-demographic and clinical variables and insulin therapy practice were analyzed through the absolute and relative frequencies, Fisher's exact test and prevalence ratio (PR). Results: The association between types of insulin (60.0%), administered with a disposable syringe attached to a needle (80...
May 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28552022/international-infectious-diseases-teaching-to-undergraduate-medical-students-a-successful-european-collaborative-experience
#9
Caroline Charlier, Ingólfur Johannessen, Claire L Mackintosh, David Wilks, Roberto Cauda, Federica I Wolf, Claire Le Jeunne
CONTEXT: The emerging global-health paradigm requires medical teaching to be continuously redefined and updated; to this end, transnational approaches should be encouraged and medical training harmonized. Infectious diseases (ID) teaching in the current context of emerging infections, fast-increasing bacterial resistance and large-scale human migration, was chosen to develop a common international course. OBJECTIVE: We report the successful implementation of a joint European undergraduate course aiming to (i) develop a common ID core curriculum among European medical schools; (ii) promote mobility among teachers and students (iii) promote international cooperation among European teachers...
September 2017: Medical Teacher
https://www.readbyqxmd.com/read/28547745/medical-students-and-professional-anatomists-do-not-perceive-gender-bias-within-imagery-featuring-anatomy
#10
Susan Morgan, Odile Plaisant, Baptiste Lignier, Bernard J Moxham
Previous studies suggest that, while both medical students and professional anatomists recognize the importance of gender issues and do not wish to associate with sexism, most are unaware of the possible negative aspects of sexism within anatomy (Morgan et al. , J. Anat. 224:352-365; , Clin. Anat. 29:892-910). To further investigate this issue, we provided second year medical students at Cardiff University (n = 293) and at the University of Paris Descartes, Sorbonne Paris Cité (n = 142) and professional anatomists (n = 208) with a questionnaire inviting them to address the possibility that gender factors within anatomical imagery (both historical and contemporary) hinder the dispassionate representation of anatomy...
May 25, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28486700/dysregulation-of-the-adam17-notch-signalling-pathways-in-endometriosis-from-oxidative-stress-to-fibrosis
#11
Iñaki González-Foruria, Pietro Santulli, Sandrine Chouzenoux, Francisco Carmona, Charles Chapron, Frédéric Batteux
STUDY QUESTION: Is oxidative stress associated with the A disintegrin and metalloproteases (ADAM) metallopeptidase domain 17 (ADAM17)/Notch signalling pathway and fibrosis in the development of endometriosis? SUMMARY ANSWER: Oxidative stress is correlated with hyperactivation of the ADAM17/Notch signalling pathway and a consequent increase in fibrosis in patients with endometriosis. WHAT IS KNOWN ALREADY: It is nowadays accepted that oxidative stress plays an important role in the onset and progression of endometriosis...
May 9, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/28376980/an-experimental-study-of-implicit-racial-bias-in-recognition-of-child-abuse
#12
Mary Rojas, Ingrid Walker-Descartes, Danielle Laraque-Arena
OBJECTIVES: We evaluated whether implicit racial bias influences pediatricians' suspicion of child abuse. METHODS: Child abuse experts developed 9 injury vignettes. Pediatricians (N = 342) were randomly assigned one of 2 versions to rate for suspicion of abuse, with the child's race in each vignette varying between white and black. Data were collected online and anonymously. RESULTS: There were no statistically significant differences in suspicion for an abuse-related injury based on the race of the child...
May 1, 2017: American Journal of Health Behavior
https://www.readbyqxmd.com/read/28359768/on-the-science-of-consciousness-epistemological-reflections-and-clinical-implications
#13
Enrico Facco, Daniela Lucangeli, Patrizio Tressoldi
Consciousness has been one of the most important and tantalizing issues ever since the origin of philosophy and medicine. The concept of consciousness and the so-called "hard problem" (i.e., the mind-brain relationship) are highly complex topics that have yet to be elucidated, involving the realms of both science and philosophy with profound epistemological implications. In the lively debate on the foundations of the science of consciousness there are several potential biases of an essentially philosophical nature, such as those related to the paradigm and axioms adopted, and the ostensible logical contradiction between monism and dualism...
May 2017: Explore: the Journal of Science and Healing
https://www.readbyqxmd.com/read/28336221/the-use-of-contact-lens-telescopic-systems-in-low-vision-rehabilitation
#14
REVIEW
Stephen J Vincent
Refracting telescopes are afocal compound optical systems consisting of two lenses that produce an apparent magnification of the retinal image. They are routinely used in visual rehabilitation in the form of monocular or binocular hand held low vision aids, and head or spectacle-mounted devices to improve distance visual acuity, and with slight modifications, to enhance acuity for near and intermediate tasks. Since the advent of ground glass haptic lenses in the 1930's, contact lenses have been employed as a useful refracting element of telescopic systems; primarily as a mobile ocular lens (the eyepiece), that moves with the eye...
March 20, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28205048/mild-orotic-aciduria-in-umps-heterozygotes-a-metabolic-finding-without-clinical-consequences
#15
Saskia B Wortmann, Margaret A Chen, Roberto Colombo, Alessandro Pontoglio, Bader Alhaddad, Lorenzo D Botto, Tatiana Yuzyuk, Curtis R Coughlin, Maria Descartes, Stephanie Grűnewald, Bruno Maranda, Philippa B Mills, James Pitt, Catherine Potente, Richard Rodenburg, Leo A J Kluijtmans, Srirangan Sampath, Emil F Pai, Ron A Wevers, George E Tiller
BACKGROUND: Elevated urinary excretion of orotic acid is associated with treatable disorders of the urea cycle and pyrimidine metabolism. Establishing the correct and timely diagnosis in a patient with orotic aciduria is key to effective treatment. Uridine monophosphate synthase is involved in de novo pyrimidine synthesis. Uridine monophosphate synthase deficiency (or hereditary orotic aciduria), due to biallelic mutations in UMPS, is a rare condition presenting with megaloblastic anemia in the first months of life...
May 2017: Journal of Inherited Metabolic Disease
https://www.readbyqxmd.com/read/28198956/evaluating-pharmaceutical-waste-disposal-in-pediatric-units
#16
Maria Angélica Randoli de Almeida, Ana Maria Miranda Martins Wilson, Maria Angélica Sorgini Peterlini
OBJECTIVE: To verify the disposal of pharmaceutical waste performed in pediatric units. METHOD: A descriptive and observational study conducted in a university hospital. The convenience sample consisted of pharmaceuticals discarded during the study period. Handling and disposal during preparation and administration were observed. Data collection took place at pre-established times and was performed using a pre-validated instrument. RESULTS: 356 drugs disposals were identified (35...
November 2016: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/28194930/representation-archaeology-and-genealogy-three-spatial-metaphors-for-inquiring-into-nursing-phenomena-with%C3%A2-foucauldian-discourse-analysis
#17
Michael E Clinton, Rusla Anne Springer
Foucault used the "Quadrilateral of Language" metaphor to describe how language functioned in what the French called the Classic Age, roughly 1650 to 1800, the period from Descartes to Kant. His purpose was to show how the functions of language changed radically with the arrival of the Modern Age (~1800). Foucault developed his archaeological methods to investigate the impact of this change, but later revised his methods to introduce genealogical strategies to conduct "histories of the present". Our purpose in this paper is to clarify Foucault's thinking about ruptures in the functions of language and to show their implications for analyzing nursing discourse...
February 14, 2017: Nursing Philosophy: An International Journal for Healthcare Professionals
https://www.readbyqxmd.com/read/28186535/long-term-risks-of-kidney-living-donation-review-and-position-paper-by-the-era-edta-descartes-working-group
#18
Umberto Maggiore, Klemens Budde, Uwe Heemann, Luuk Hilbrands, Rainer Oberbauer, Gabriel C Oniscu, Julio Pascual, Soren Schwartz Sorensen, Ondrej Viklicky, Daniel Abramowicz
Two recent matched cohort studies from the USA and Norway published in 2014 have raised some concerns related to the long-term safety of kidney living donation. Further studies on the long-term risks of living donation have since been published. In this position paper, Developing Education Science and Care for Renal Transplantation in European States (DESCARTES) board members critically review the literature in an effort to summarize the current knowledge concerning long-term risks of kidney living donation to help physicians for decision-making purposes and for providing information to the prospective live donors...
February 1, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28134051/descartes-cardiac-heat-and-alchemy
#19
Dorothea Heitsch
René Descartes (1596-1650) insisted on a heat and light theory to explain cardiac movement, and used concepts such as distillation of the vital spirits, fermentation in the digestive process, and fermentation in the circulation of the blood. I argue that his theory of the body as a heat-exchange system was based on alchemical and natural philosophical notions of fire and light expounded by precursors and contemporaries who included Jean D'Espagnet, Jean Fernel, Jan Baptist van Helmont, and Andreas Libavius...
November 2016: Ambix
https://www.readbyqxmd.com/read/27938723/from-secondary-causes-to-artificial-instruments-pierre-sylvain-r%C3%A3-gis-s-rethinking-of-scholastic-accounts-of-causation
#20
Andrea Sangiacomo
Although several of Descartes's disciples established occasionalism as the natural outcome of Cartesianism, Pierre-Sylvain Régis forcefully resisted this conclusion by developing an account of secondary causes in which God does not immediately intervene in the natural world. In order to understand this view, it has been argued that Régis melds Aquinas's concurrentism with the new, mechanist natural philosophy defended in Cartesian physics. In this paper, I contend that such a reading of Régis's position is misleading for our understanding of both his account of secondary causality and the relationship between medieval debates and seventeenth century natural philosophy...
December 2016: Studies in History and Philosophy of Science
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