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Mastectomy in dogs

L Soler, N García, A Unzueta, M Piñeiro, M A Álava, F Lampreave
Inter-α-trypsin inhibitor heavy chain 4 (ITIH4) and C-reactive protein (CRP) have been isolated from acute phase dog sera by affinity chromatography with insolubilized polyclonal antibodies anti pig Major Acute phase Protein (Pig-MAP) and with p-Aminophenyl Phosphoryl Choline, respectively. Isolated proteins were used to prepare specific polyclonal rabbit antisera that have allowed quantifying their concentration in serum samples by single radial immunodifussion. Both proteins were quantified in sera from female dogs that had undergone ovariohysterectomy (OVH, n=9) or mastectomy (n=10)...
October 15, 2016: Veterinary Immunology and Immunopathology
A Lenne, L Defourny, A Lafosse, M Martin, B Vandercam, M Berlière, B Lengelé, H Rodriguez-Villalobos
INTRODUCTION: Pets are not always the human's best friends, particularly in the presence of comorbidities such as wounds. The following case report describes a Pasteurella multocida infection of a reconstructive breast implant due to a close contact between a cat and its owner. PRESENTATION OF CASE: A 33-year-old woman developed a breast implant infection 13 days after an immediate breast reconstruction following a mastectomy for a multifocal ductal carcinoma. The wound was explored surgically and the implant removed...
2016: International Journal of Surgery Case Reports
Geok Hoon Lim, Hui Fuan Tan
INTRODUCTION: Mastectomy is commonly performed for breast cancer. However, a dog ear may arise at the lateral aspect of the mastectomy scar. This dog ear is not only unsightly but can also be a source of discomfort. While various surgical techniques have been reported to tackle this lateral dog ear, there is no standardized technique. We hence conduct the first systematic review of these surgical techniques with the aim of comparing the merits and limitations of each technique. METHODS: A systematic literature search using the search terms "mastectomy scar", "mastectomy dog ear", "mastectomy lateral fold" and "mastectomy cosmesis" was performed...
February 2016: International Journal of Surgery
V M Kristiansen, L Peña, L Díez Córdova, J C Illera, E Skjerve, A M Breen, M A Cofone, M Langeland, J Teige, M Goldschmidt, K U Sørenmo
BACKGROUND: Ovarian hormones play crucial roles in mammary carcinogenesis. However, whether ovarian ablation by ovariohysterectomy (OHE) improves the prognosis in dogs with mammary carcinomas is unclear. OBJECTIVES: Determine if OHE at the time of mastectomy improves the prognosis in dogs with mammary carcinomas and evaluate if hormonal factors influence the effect of OHE. ANIMALS: Sixty intact dogs with mammary carcinomas. METHODS: Dogs were randomly assigned in a 1:1 ratio to undergo OHE (n = 31) or not (n = 29) at the time of tumor removal...
January 2016: Journal of Veterinary Internal Medicine
S Vilhegas, R N Cassu, R C Barbero, G C Crociolli, T L A Rocha, D R Gomes
The aim of this randomised placebo-controlled, observer-blinded study was to evaluate the analgesic effects of botulinum toxin type A (BoNT-A) as an adjunct for postoperative pain control in dogs. Sixteen dogs undergoing bilateral radical mastectomy for treatment of mammary tumours were enrolled. Twenty-four hours before surgery, the subjects were distributed into two groups of eight dogs each: 7 iu/kg BoNT-A (BoNT-A) or saline (Control) was administered subcutaneously in each mammary gland. Following sedation with intramuscular 0...
October 17, 2015: Veterinary Record
Rodrigo S Horta, Mariana S Figueiredo, Gleidice E Lavalle, Mariana P Costa, Rubia M C Cunha, Roberto B Araújo
BACKGROUND: Surgery is the treatment of choice for regional control of mammary neoplasms in female dogs. Various surgical techniques may be used, as long as mammary gland anatomy, lymphatic drainage, and known prognostic factors are respected. The purpose of this study was to compare surgical stress-including duration of surgery, nociception and hematological changes-and postoperative complications in dogs undergoing regional and unilateral radical mastectomy. Eighteen dogs were selected for each technique...
2015: Acta Veterinaria Scandinavica
Giulianne Carla Crociolli, Renata Navarro Cassu, Rafael Cabral Barbero, Thalita Leone A Rocha, Denis Robson Gomes, Gabriel Montoro Nicácio
This study aimed to evaluate the analgesic efficacy of gabapentin as an adjuvant for postoperative pain management in dogs. Twenty dogs undergoing mastectomy were randomized to receive perioperative oral placebo or gabapentin (10 mg/kg). All dogs were premedicated with intramuscular acepromazine (0.03 mg/kg) and morphine (0.3 mg/ kg). Anesthesia was induced with propofol (4 mg/kg) intravenously and maintained with isoflurane. Intravenous meloxicam (0.2 mg/kg) was administered preoperatively. Postoperative analgesia was evaluated for 72 hr...
August 2015: Journal of Veterinary Medical Science
Nilgun Gultiken, Tolga Guvenc, Duygu Kaya, Ali Reha Agaoglu, Serhan Serhat Ay, Ibrahim Kucukaslan, Birten Emre, Murat Findik, Sabine Schäfer-Somi, Selim Aslan
In the present study, 13 clinical cases of canine mammary adenocarcinoma were evaluated in order to understand the effect of Tarantula cubensis extract (TCE) on tumor tissue. Punch biopsies were taken from the tumors before treatment with TCE. Subcutaneous injections of TCE were administered three times at weekly intervals (3 mL per dog). Between days 7 and 10 after the third injection, the tumor masses were extirpated by complete unilateral mastectomy. Pre- and post-treatment tumor tissues were immunohistochemically assessed...
2015: Journal of Veterinary Science
Suresh Sathya, Kathleen Linn
An 11 yr old female mixed-breed Siberian husky was presented with a history of sanguineous vaginal discharge, swelling of the perineal area, decreased appetite, and lethargy. A single, large vaginal leiomyoma and multiple mammary tumors were diagnosed. Mastectomy and ovariohysterectomy were performed. The vaginal leiomyoma regressed completely after ovariohysterectomy. This is the first reported case of spontaneous regression of a vaginal leiomyoma after ovariohysterectomy in a dog.
November 2014: Journal of the American Animal Hospital Association
Alejandro Rubio, Filip Boyen, Olaf Tas, Adriaan Kitshoff, Ingeborgh Polis, Bart Van Goethem, Hilde de Rooster
Septic peritonitis occurs relatively commonly in dogs. Secondary septic peritonitis is usually associated with perforation of intestines or infected viscera, such as the uterus in pyometra cases. The aim of this study was to evaluate the bacterial flora in the ovarian bursae of intact bitches as a potential source of contamination. One hundred forty dogs, clinically suspected of pyometra, were prospectively enrolled. The control group consisted of 26 dogs that underwent elective ovariohysterectomies and 18 dogs with mammary gland tumors that were neutered at the time of mastectomy...
October 15, 2014: Theriogenology
Caio J X Abimussi, Thais M Menegheti, Juliana T Wagatsuma, Beatriz P Floriano, André M M Arruda, Paulo S P dos Santos, Valéria N L S Oliva
OBJECTIVE: To compare two concentrations of ropivacaine administered for tumescent local anesthesia (TLA) in dogs undergoing mastectomy. STUDY DESIGN: Prospective randomized clinical study. ANIMALS: Seventeen bitches of various breeds, aged 12 ± 2 years and weighing 10 ± 6.5 kg requiring total unilateral or bilateral mastectomy. METHODS: Dogs were premedicated with acepromazine (0.04 mg kg(-1) ) and morphine (0...
September 2014: Veterinary Anaesthesia and Analgesia
Diego A Portela, Marta Romano, Angela Briganti
HISTORY: Eleven female dogs of different breeds undergoing unilateral radical (n = 7) or regional abdominal mastectomy (n = 4) received an ultrasound guided transverse abdominis plane block (TAP-block). PHYSICAL EXAMINATION: Subjects showed single or multiple mammary tumours. Serum biochemistry, CBC and electrocardiogram were unremarkable. Eight animals were classified as ASA physical status II and 3 as ASA III. MANAGEMENT: Dogs were premedicated with methadone [0...
May 2014: Veterinary Anaesthesia and Analgesia
Leonardo de Freitas Guimaraes Arcoverde Credie, Stelio Pacca Loureiro Luna, Fabio Futema, Luciano Cacciari Baruffaldi Almeida da Silva, Giancarlo Bressane Gomes, Jaqueline Neratika Negrette Garcia, Lidia Raquel de Carvalho
BACKGROUND: Tumescent anaesthesia (TA) is a widely used technique in oncologic surgeries necessitating large resection margins. This technique produces transoperative and postoperative analgesia, reduces surgical bleeding, and facilitates tissue divulsion. This prospective, randomised, blind study evaluated the use of TA in bitches submitted to mastectomy and compared the effect of TA with an intravenous fentanyl bolus. A 2.5-mcg/kg intravenous fentanyl bolus (n = 10) was compared with TA using 0...
2013: BMC Veterinary Research
Bruno W Minto, Lisiane C Rodrigues, Paulo V M Steagall, Eduardo R Monteiro, Claudia V S Brandão
BACKGROUND: There are few studies reporting pain and postoperative analgesia associated with mastectomy in dogs. The aim of this study was to evaluate postoperative pain after unilateral mastectomy using two different surgical techniques in the dog. FINDINGS: Twenty female dogs were assigned (n=10/group) to undergo unilateral mastectomy using either the combination of sharp and blunt dissection (SBD) or the modified SBD (mSBD) technique, in which the mammary chain is separated from the abdominal wall entirely by blunt (hand and finger) dissection except for a small area cranial to the first gland, in a prospective, randomized, clinical trial...
2013: Acta Veterinaria Scandinavica
Radmehr Shafiee, Javad Javanbakht, Nahid Atyabi, Pegah Kheradmand, Danial Kheradmand, Alimohammad Bahrami, Hasti Daraei, Farshid Khadivar
BACKGROUND: The human "Elston and Ellis grading method" was utilized in dogs with mammary tumor to examine its relation to prognosis in this species, based on a 2-year follow-up period. Although cytopathology is widely used for early diagnosis of human neoplasms, it is not commonly performed in veterinary medicine. Our objectives in this study were to identify cytopathology criteria of malignancy for canine mammary tumors and the frequency of different types of mammary lesions and their relationship with histologic grade was investigated...
2013: Cancer Cell International
Breno S Salgado, Lidianne N Monteiro, Márcia M Colodel, Fernanda C Figueiroa, Luisa M Soares, Suely Nonogaki, Rafael M Rocha, Noeme S Rocha
Mammary invasive micropapillary carcinoma is a rare variant of mammary carcinoma that was recently recognized in dogs. The cytologic features and biologic behavior of such neoplasms in dogs have not yet been widely discussed in the veterinary literature. We report the clinical, cytologic, and histologic features of a canine micropapillary carcinoma in a 13-year-old female mongrel dog. The mammary region presented with extreme local pain, severe edema and erythema, and multifocal epidermal ulceration, which is typical for an inflammatory mammary carcinoma...
September 2013: Veterinary Clinical Pathology
Renata Cr Teixeira, Eduardo R Monteiro, Daniela Campagnol, Karina Coelho, Thais F Bressan, Betânia S Monteiro
OBJECTIVE: To compare the effects of tramadol alone, or in combination with dipyrone or meloxicam, on postoperative pain and analgesia requirement after unilateral mastectomy with or without ovariohysterectomy in dogs. STUDY DESIGN: Prospective, randomized, clinical study. ANIMALS: Twenty seven bitches undergoing unilateral mastectomy with or without ovariohysterectomy. METHODS: Anesthesia was induced with propofol and maintained with isoflurane and a constant rate infusion of morphine...
November 2013: Veterinary Anaesthesia and Analgesia
Karol M Pawłowski, Joanna Mucha, Kinga Majchrzak, Tomasz Motyl, Magdalena Król
BACKGROUND: In both women and female dogs, the most prevalent type of malignant neoplasm is the spontaneous mammary tumor. In dogs, half of these are malignant. The treatment of choice for the canine patients is surgical mastectomy. Unfortunately, it often fails in high-risk, locally invasive mammary tumors as of during the time of the surgery the micro-metastases are present. Moreover, there are neither large studies conducting to prove of the benefit from the chemotherapy in dogs nor established chemotherapy treatment protocols available...
2013: BMC Veterinary Research
Masahito Komuro, Kenichi Suzuki, Makoto Kanebako, Takashi Kawahara, Takeshige Otoi, Kenji Kitazato, Toshio Inagi, Kimiko Makino, Masakazu Toi, Hiroshi Terada
Ductal drug therapy is a novel therapeutic approach for primary breast cancers, particularly those involving ductal carcinoma in situ lesions. Total or partial mastectomy with or without radiotherapy is the standard local therapy for primary breast cancer. Here, we propose a novel drug administration method for ductal drug therapy based on a drug delivery system (DDS) for primary breast cancer. This DDS was designed to deliver miproxifen phosphate (TAT-59), an antiestrogen drug, to ductal lesions via the milk duct, where carcinomas originate, more efficiently than systemic administration, using an iontophoretic technique applied to the nipple (IP administration)...
June 28, 2013: Journal of Controlled Release: Official Journal of the Controlled Release Society
Rebecca Thomas, Christine Mouat, Burton King
BACKGROUND: There are various methods to design mastectomy flaps but few are standardized. Lateral skin folds or 'dog ears' are a common, unsightly and uncomfortable consequence following a surgery in overweight patients. METHODS: We describe a simple technique for designing mastectomy flaps and a method to eliminate the lateral dog ear. CONCLUSION: The design is easy to apply and may enable standardization. Heuristics of mastectomy design should be standardized and included in surgical training...
May 2012: ANZ Journal of Surgery
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