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https://www.readbyqxmd.com/read/28822955/studying-the-old-masters-of-nursing-a-critical-student-experience-for-developing-nursing-identity
#1
Jacinta Kelly, Roger Watson, James Watson, Malachi Needham, Laura O Driscoll
In the past professional identity in nursing was inculcated in students alongside institutional pride. A strong sense of professional identity is key to staff retention and recruitment and key to the delivery of quality nursing care. With the wholesale transfer of pre-registration nursing education to the third level sector, however, the reality is that students now divide their affiliations between university and healthcare institutions and professional identity development may be stymied. For this reason, there is need to explore alternative means of developing professional identity...
July 4, 2017: Nurse Education in Practice
https://www.readbyqxmd.com/read/28822827/host-genes-regulate-transcription-of-sperm-introduced-hepatitis-b-virus-genes-in-embryo
#2
Ying Zhong, Dong-Ling Liu, Mohamed Morsi M Ahmed, Peng-Hao Li, Xiao-Ling Zhou, Qing-Dong Xie, Xiao-Qing Xu, Ting-Ting Han, Zhi-Wei Hou, Chen-Yao Zhong, Ji-Hua Huang, Fei Zeng, Tian-Hua Huang
Hepatitis B virus (HBV) can invade the male germline, and sperm-introduced HBV genes could be transcribed in embryo. This study was to explore whether viral gene transcription is regulated by host genes. Embryos were produced by in vitro fertilization of hamster oocytes with human sperm containing the HBV genome. Total RNA extracted from test and control embryos were subjected to SMART-PCR, SSH, microarray hybridization, sequencing and BLAST analysis. Twenty-nine sequences showing significant identity to five human gene families were identified, with CSH2, EIF4G2, PCBD2, PSG4 and TTN selected to represent target genes...
August 16, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28821649/effector-invariant-movement-encoding-in-the-human-motor-system
#3
Shlomi Haar, Ilan Dinstein, Ilan Shelef, Opher Donchin
Ipsilateral motor areas of cerebral cortex are active during arm movements and even reliably predict movement direction. Is coding similar during ipsilateral and contralateral movements? If so, is it in extrinsic (world-centered) or intrinsic (joint-configuration) coordinates? We addressed these questions by examining the similarity of multi-voxel fMRI patterns in visuomotor cortical regions during unilateral reaching movements with both arms. The results of three complementary analyses revealed that fMRI response patterns were similar across right and left arm movements to identical targets (extrinsic coordinates) in visual cortices, and across movements with equivalent joint-angles (intrinsic coordinates) in motor cortices...
August 16, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28821591/specifying-cell-fate-in-roots-requires-coordinative-lineage-instruction-and-positional-reprogramming
#4
Qiaozhi Yu, Pengxue Li, Nengsong Liang, Hong Wang, Meizhi Xu, Shuang Wu
Tissue organization and pattern formation within a multicellular organism relies on coordinated cell division and cell fate determination. In animals cell fates are mainly determined by a cell lineage dependent mechanism, whereas in plants positional information is thought to be the primary determinant of cell fates (Scheres, 2001; Kidner et al., 2000; Kim et al., 2005; Scheres et al., 2002). However, our understanding of cell fate regulation in plants mostly relies on the histological and anatomical studies on Arabidopsis roots which contain a single layer of each cell type in non-vascular tissues (Scheres et al...
August 18, 2017: Plant Physiology
https://www.readbyqxmd.com/read/28821530/whisper-or-shout-study-protocol-of-a-cluster-randomised-controlled-trial-assessing-mhealth-sexual-reproductive-health-and-nutrition-interventions-among-female-sex-workers-in-mombasa-kenya
#5
Frances H Ampt, Collins Mudogo, Peter Gichangi, Megan S C Lim, Griffins Manguro, Matthew Chersich, Walter Jaoko, Marleen Temmerman, Marilyn Laini, Liz Comrie-Thomson, Mark Stoové, Paul A Agius, Margaret Hellard, Kelly L'Engle, Stanley Luchters
INTRODUCTION: New interventions are required to reduce unintended pregnancies among female sex workers (FSWs) in low- and middle-income countries and to improve their nutritional health. Given sex workers' high mobile phone usage, repeated exposure to short messaging service (SMS) messages could address individual and interpersonal barriers to contraceptive uptake and better nutrition. METHODS: In this two-arm cluster randomised trial, each arm constitutes an equal-attention control group for the other...
August 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28821291/who-and-where-are-the-uncounted-children-inequalities-in-birth-certificate-coverage-among-children-under-five-years-in-94-countries-using-nationally-representative-household-surveys
#6
Amiya Bhatia, Leonardo Zanini Ferreira, Aluísio J D Barros, Cesar Gomes Victora
BACKGROUND: Birth registration, and the possession of a birth certificate as proof of registration, has long been recognized as a fundamental human right. Data from a functioning civil registration and vital statistics (CRVS) system allows governments to benefit from accurate and universal data on birth and death rates. However, access to birth certificates remains challenging and unequal in many low and middle-income countries. This paper examines wealth, urban/rural and gender inequalities in birth certificate coverage...
August 18, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28819308/an-optimal-mean-based-block-robust-feature-extraction-method-to-identify-colorectal-cancer-genes-with-integrated-data
#7
Jian Liu, Yuhu Cheng, Xuesong Wang, Lin Zhang, Hui Liu
It is urgent to diagnose colorectal cancer in the early stage. Some feature genes which are important to colorectal cancer development have been identified. However, for the early stage of colorectal cancer, less is known about the identity of specific cancer genes that are associated with advanced clinical stage. In this paper, we conducted a feature extraction method named Optimal Mean based Block Robust Feature Extraction method (OMBRFE) to identify feature genes associated with advanced colorectal cancer in clinical stage by using the integrated colorectal cancer data...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28818083/optimization-of-the-biotechnological-production-of-a-novel-class-of-anti-mrsa-antibiotics-from-chitinophaga-sancti
#8
Amelie Beckmann, Stephan Hüttel, Viktoria Schmitt, Rolf Müller, Marc Stadler
BACKGROUND: Recently, the discovery of the elansolids, a group of macrolides, was reported. The molecules show activity against methicillin-resistant Staphylococcus aureus as well as other gram-positive organisms. This fact renders those substances a promising starting point for future chemical development. The active atropisomers A1/A2 are formed by macrolactonization of the biosynthesis product A3 but are prone to ring opening and subsequent formation of several unwanted side products...
August 17, 2017: Microbial Cell Factories
https://www.readbyqxmd.com/read/28818020/preserving-self-theorizing-the-social-and-psychological-processes-of-living-with-parkinson-disease
#9
Terrie Vann-Ward, Janice M Morse, Kathy Charmaz
The purpose of this constructivist grounded theory article is to identify, explore, and theorize the social and psychological processes used by people with Parkinson disease. Analytic procedures generated the five-stage theory of Preserving self of people with Parkinson disease: (a) making sense of symptoms, (b) defining turning points, (c) experiencing identity dilemmas, (d) reconnecting the self, and (e) envisioning a future. Reminders of former selves and capabilities were painful; participants desperately sought normalcy...
June 2017: Qualitative Health Research
https://www.readbyqxmd.com/read/28817631/a-computational-model-for-biosonar-echoes-from-foliage
#10
Chen Ming, Anupam Kumar Gupta, Ruijin Lu, Hongxiao Zhu, Rolf Müller
Since many bat species thrive in densely vegetated habitats, echoes from foliage are likely to be of prime importance to the animals' sensory ecology, be it as clutter that masks prey echoes or as sources of information about the environment. To better understand the characteristics of foliage echoes, a new model for the process that generates these signals has been developed. This model takes leaf size and orientation into account by representing the leaves as circular disks of varying diameter. The two added leaf parameters are of potential importance to the sensory ecology of bats, e...
2017: PloS One
https://www.readbyqxmd.com/read/28817436/why-do-general-surgeons-decide-to-retire-a-population-level-survey
#11
Heather M Poushay, Daniel J Kagedan, Julie Hallet, Lesley Gotlib Conn, Kaitlyn Beyfuss, Ashlie Nadler, Najma Ahmed, Frances C Wright
: Limited recent data exist regarding intended retirement plans for general surgeons (GS). We sought to understand when and why surgeons decide to stop operating as primary surgeon and stop all clinical work.A paper-based survey of practicing GS in the province of Ontario, Canada, was conducted. A questionnaire was developed using a systematic approach of item generation and reduction. Face and content validity were tested. The survey was administered via mail, with a planned reminder.Overall response rate was 33...
August 16, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28816668/fast-open-world-person-re-identification
#12
Xiatian Zhu, Botong Wu, Dongcheng Huang, Wei-Shi Zheng
Existing person re-identification (re-id) methods typically assume that (1) any probe person is guaranteed to appear in the gallery target population during deployment (i.e. closed-world), and (2) the probe set contains only a limited number of people (i.e. small search scale). Both assumptions are artificial and breached in real-world applications, since the probe population in target people search can be extremely vast in practice due to the ambiguity of probe search space boundary. Therefore, it is unrealistic that any probe person is assumed as one target people, and a large-scale search in person images is inherently demanded...
August 16, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28816583/mammalian-cell-surface-display-for-monoclonal-antibody-based-facs-selection-of-viral-envelope-proteins
#13
Tim-Henrik Bruun, Veronika Grassmann, Benjamin Zimmer, Benedikt Asbach, David Peterhoff, Alexander Kliche, Ralf Wagner
The elicitation of broadly and efficiently neutralizing antibodies in humans by active immunization is still a major obstacle in the development of vaccines against pathogens such as the human immunodeficiency virus (HIV), influenza virus, hepatitis C virus or cytomegalovirus. Here, we describe a mammalian cell surface display and monoclonal antibody (mAb)-mediated panning technology that allows affinity-based selection of envelope (Env) variants from libraries. To this end, we established an experimental setup featuring: 1) single and site specific integration of Env to link genotype and phenotype, 2) inducible Env expression to avoid cytotoxicity effects, 3) translational coupling of Env and enhanced green fluorescent protein expression to normalize for Env protein levels, and 4) display on HEK cells to ensure native folding and mammalian glycosylation...
August 17, 2017: MAbs
https://www.readbyqxmd.com/read/28815506/preparing-fosmid-mate-paired-libraries-using-cre-loxp-recombination
#14
Ze Peng, Jeff L Froula, Jan-Fang Cheng
Fosmid end sequencing has been widely utilized in genome sequence assemblies and genome structural variation studies. We have developed a new approach to construct fosmid paired-end libraries that is suitable for Illumina sequencing platform. This approach employs a newly modified fosmid vector (pFosClip) which contains two loxP sites with identical orientation and two inverse Illumina adaptor priming sites flanking the cloning site. DNA prepared from the fosmid library constructed with pFosClip can be treated with the Cre recombinase to remove most of the vector DNA, leaving only 107 bp of the vector sequence with insert DNA...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28814545/metabolic-differentiation-of-early-lyme-disease-from-southern-tick-associated-rash-illness-stari
#15
Claudia R Molins, Laura V Ashton, Gary P Wormser, Barbara G Andre, Ann M Hess, Mark J Delorey, Mark A Pilgard, Barbara J Johnson, Kristofor Webb, M Nurul Islam, Adoracion Pegalajar-Jurado, Irida Molla, Mollie W Jewett, John T Belisle
Lyme disease, the most commonly reported vector-borne disease in the United States, results from infection with Borrelia burgdorferi. Early clinical diagnosis of this disease is largely based on the presence of an erythematous skin lesion for individuals in high-risk regions. This, however, can be confused with other illnesses including southern tick-associated rash illness (STARI), an illness that lacks a defined etiological agent or laboratory diagnostic test, and is coprevalent with Lyme disease in portions of the eastern United States...
August 16, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28814343/stable-inheritance-of-dna-methylation-allows-creation-of-epigenotype-maps-and-the-study-of-epiallele-inheritance-patterns-in-the-absence-of-genetic-variation
#16
Brigitte T Hofmeister, Kevin Lee, Nicholas A Rohr, David W Hall, Robert J Schmitz
BACKGROUND: Differences in DNA methylation can arise as epialleles, which are loci that differ in chromatin state and are inherited over generations. Epialleles offer an additional source of variation that can affect phenotypic diversity beyond changes to nucleotide sequence. Previous research has looked at the rate at which spontaneous epialleles arise but it is currently unknown how they are maintained across generations. RESULTS: We used two Arabidopsis thaliana mutation accumulation (MA) lines and determined that over 99...
August 16, 2017: Genome Biology
https://www.readbyqxmd.com/read/28813702/tocolysis-for-in-utero-surgery-atosiban-performs-distinctly-better-than-magnesium-sulfate
#17
Nicole Ochsenbein-Kölble, Franziska Krähenmann, Margret Hüsler, Martin Meuli, Ueli Moehrlen, Lucca Mazzone, Peter Biro, Roland Zimmermann
INTRODUCTION: To compare tocolysis with magnesium sulfate versus atosiban regarding the occurrence of short-term preterm labor and maternal side effects during and after open fetal myelomeningocele (MMC) repair. MATERIAL AND METHODS: A prospective nonrandomized cohort study was performed including 30 fetal MMC cases. The first 15 cases (group 1) received magnesium sulfate according to the MOMS protocol. In the following 15 cases (group 2), magnesium sulfate was substituted by atosiban...
August 17, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/28813696/effects-of-standardized-home-training-in-patients-with-cognitive-impairment-following-geriatric-rehabilitation-a-randomized-controlled-pilot-study
#18
Klaus Hauer, Phoebe Ullrich, Ilona Dutzi, Rainer Beurskens, Sylvia Kern, Jürgen Bauer, Michael Schwenk
BACKGROUND: Post-ward geriatric rehabilitation programs have hardly been developed and validated, which leaves a substantial gap in rehabilitative care in older adults and hinders full exploitation of maintained, but often unrecognized rehabilitation potentials. Geriatric rehabilitation patients with cognitive impairment represent a highly vulnerable population which is often affected by a lack of an ongoing support at the intersection between ward-based and post-ward rehabilitation. OBJECTIVE: To determine the effect of a standardized home-based training program in geriatric patients with cognitive impairment following ward-based rehabilitation...
August 17, 2017: Gerontology
https://www.readbyqxmd.com/read/28813337/professional-development-for-sport-psychology-practice
#19
REVIEW
David Tod, R I Vana Hutter, Martin Eubank
Applied sport psychology practice and research date back to the late 19th century. During this period investigators have largely examined the interventions practitioners employ to help athletes. More recently, researchers have begun addressing the person employing those interventions, including identifying their attributes and how they develop expertise, in recognition that practitioners are central to effective practice. Research focused on practitioners can inform educational and registration pathways, helping trainees to develop the knowledge, skills, and characteristics needed to meet their clients' needs...
August 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28813333/athletic-identity-foreclosure
#20
REVIEW
Britton W Brewer, Albert J Petitpas
Athletic identity foreclosure refers to commitment to the athlete role in the absence of exploration of occupational or ideological alternatives. This article traces the theoretical underpinnings of the construct, examines the role of sport participation in identity development, and provides an overview of the course, correlates, and consequences of athletic identity foreclosure. Implications for future research are discussed.
August 2017: Current Opinion in Psychology
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