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https://www.readbyqxmd.com/read/28632873/screening-for-obesity-and-intervention-for-weight-management-in-children-and-adolescents-evidence-report-and-systematic-review-for-the-us-preventive-services-task-force
#1
Elizabeth A O'Connor, Corinne V Evans, Brittany U Burda, Emily S Walsh, Michelle Eder, Paula Lozano
Importance: Obesity is common in children and adolescents in the United States, is associated with negative health effects, and increases the likelihood of obesity in adulthood. Objective: To systematically review the benefits and harms of screening and treatment for obesity and overweight in children and adolescents to inform the US Preventive Services Task Force. Data Sources: MEDLINE, PubMed, PsycINFO, Cochrane Collaboration Registry of Controlled Trials, and the Education Resources Information Center through January 22, 2016; references of relevant publications; government websites...
June 20, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28626500/mitophagy-transcriptome-mechanistic-insights-into-polyphenol-mediated-mitophagy
#2
REVIEW
Sijie Tan, Esther Wong
Mitochondria are important bioenergetic and signalling hubs critical for myriad cellular functions and homeostasis. Dysfunction in mitochondria is a central theme in aging and diseases. Mitophagy, a process whereby damaged mitochondria are selectively removed by autophagy, plays a key homeostatic role in mitochondrial quality control. Upregulation of mitophagy has shown to mitigate superfluous mitochondrial accumulation and toxicity to safeguard mitochondrial fitness. Hence, mitophagy is a viable target to promote longevity and prevent age-related pathologies...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28619165/the-use-of-animals-as-a-surveillance-tool-for-monitoring-environmental-health-hazards-human-health-hazards-and-bioterrorism
#3
REVIEW
Jacqueline Pei Shan Neo, Boon Huan Tan
This review discusses the utilization of wild or domestic animals as surveillance tools for monitoring naturally occurring environmental and human health hazards. Besides providing early warning to natural hazards, animals can also provide early warning to societal hazards like bioterrorism. Animals are ideal surveillance tools to humans because they share the same environment as humans and spend more time outdoors than humans, increasing their exposure risk. Furthermore, the biologically compressed lifespans of some animals may allow them to develop clinical signs more rapidly after exposure to specific pathogens...
May 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28619015/nontuberculosis-mycobacterial-infections-at-a-specialized-tuberculosis-treatment-centre-in-the-republic-of-korea
#4
Hee Jung Yoon, Hwa Young Choi, Moran Ki
BACKGROUND: The incidence of nontuberculous mycobacteria (NTM) infections is increasing worldwide, however formal evaluations of the epidemiology of NTM infections are limited. Understanding the trends and true prevalence of NTM is a major priority for optimizing infection control programmes and resources. The purpose of this study was to investigate the epidemiology, clinical manifestations, and radiologic findings in NTM-infected patients at specialized Tuberculosis (Tb) treatment centre in South Korea, which is endemic to Tb, and find solutions to control NTM infections...
June 15, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28615026/engaging-the-private-sector-in-malaria-surveillance-a-review-of-strategies-and-recommendations-for-elimination-settings
#5
Adam Bennett, Anton L V Avanceña, Jennifer Wegbreit, Chris Cotter, Kathryn Roberts, Roly Gosling
BACKGROUND: In malaria elimination settings, all malaria cases must be identified, documented and investigated. To facilitate complete and timely reporting of all malaria cases and effective case management and follow-up, engagement with private providers is essential, particularly in settings where the private sector is a major source of healthcare. However, research on the role and performance of the private sector in malaria diagnosis, case management and reporting in malaria elimination settings is limited...
June 14, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28614925/-investigation-on-standard-application-of-industrial-dust-hazard-classification
#6
Y Lu, M Zhang, W H Chen
Objective: To investigate the application and effectiveness evaluation of the standard of GBZ/T 229.1-2010 in practice, and to explore the applicability, aiming to provide technical evidence for the revision of GBZ/T 229.1-2010. Methods: There were 2 questionnaire surveys carried out in the study, including general survey and specific survey. Databases were established and data were input with Excel 2010 and Epidata version 3.1 software. SPSS version 19.0 software was used for data cleaning and statistical analysis...
April 20, 2017: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28607238/sri-lanka-takes-action-towards-a-target-of-zero-rabies-death-by-2020
#7
P A Lionel Harischandra, Amila Gunesekera, Navaratnasingam Janakan, Gyanendra Gongal, Bernadette Abela-Ridder
Rabies is a 100% vaccine-preventable and 100% fatal zoonotic, viral disease. It is usually spread to humans by saliva, through bites or scratches. Dogs are the source of the vast majority of human deaths from rabies. Political will and leadership have been the main drivers for success of the Sri Lankan effort to reduce the burden of disease attributable to rabies. Post-exposure prophylaxis, which is available in government health facilities, at no cost, to all bite patients, has been a main axis of the rabies-elimination strategy...
September 2016: WHO South-East Asia Journal of Public Health
https://www.readbyqxmd.com/read/28599616/a-survey-of-methods-used-for-antimicrobial-susceptibility-testing-in-veterinary-diagnostic-laboratories-in-the-united-states
#8
David A Dargatz, Matthew M Erdman, Beth Harris
Antimicrobial resistance is a serious threat to animal and human health worldwide, requiring a collaborative, holistic approach. The U.S. Government has developed a national strategy to address antimicrobial resistance, with one component being to monitor antimicrobial resistance in agricultural settings. We developed a survey to collect information about antimicrobial susceptibility testing (AST) from the veterinary diagnostic laboratory community in the United States, assessing current practices and technologies and determining how AST information is shared...
June 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28594945/participatory-evaluation-of-delivery-of-animal-health-care-services-by-community-animal-health-workers-in-karamoja-region-of-uganda
#9
James Bugeza, Clovice Kankya, James Muleme, Ann Akandinda, Joseph Sserugga, Noelina Nantima, Edward Okori, Terence Odoch
AIM: An evaluation exercise was carried out to assess the performance of Community Animal Health Workers (CAHWs) in the delivery of animal health care services in Karamoja region, identify capacity gaps and recommend remedial measures. MATERIALS & METHODS: Participatory methods were used to design data collection tools. Questionnaires were administered to 204 CAHWs, 215 farmers and 7 District Veterinary Officers (DVOs) to collect quantitative data. Seven DVOs and 1 Non Government Organization (NGO) representative were interviewed as key informants and one focus group discussion was conducted with a farmer group in Nakapiripirit to collect qualitative data...
2017: PloS One
https://www.readbyqxmd.com/read/28591192/perinatal-outcomes-and-congenital-heart-defect-prognosis-in-53313-non-selected-perinatal-infants
#10
Donghua Xie, Hua Wang, Zhiyu Liu, Junqun Fang, Tubao Yang, Shujin Zhou, Aihua Wang, Jiabi Qin, Lili Xiong
OBJECTIVE: To evaluate perinatal outcomes and congenital heart defect (CHD) prognosis in a non-selected population. METHODS: The population-based surveillance data used in this assessment of CHDs were based on birth defect surveillance data collected from 2010-2012 in Liuyang City, China. Infants living with CHDs were followed up for 5 years to determine their prognosis. Prevalence, prenatal diagnosis, perinatal outcomes, and total and type-specific prognosis data were assessed using SPSS 18...
2017: PloS One
https://www.readbyqxmd.com/read/28588974/practical-issues-in-the-measurement-of-child-survival-in-health-systems-trials-experience-developing-a-digital-community-based-mortality-surveillance-programme-in-rural-nepal
#11
Alex Harsha Bangura, Al Ozonoff, David Citrin, Poshan Thapa, Isha Nirola, Sheela Maru, Ryan Schwarz, Anant Raut, Bishal Belbase, Scott Halliday, Mukesh Adhikari, Duncan Maru
Child mortality measurement is essential to the impact evaluation of maternal and child healthcare systems interventions. In the absence of vital statistics systems, however, assessment methodologies for locally relevant interventions are severely challenged. Methods for assessing the under-5 mortality rate for cross-country comparisons, often used in determining progress towards development targets, pose challenges to implementers and researchers trying to assess the population impact of targeted interventions at more local levels...
November 2016: BMJ Global Health
https://www.readbyqxmd.com/read/28588951/cholera-in-the-time-of-war-implications-of-weak-surveillance-in-syria-for-the-who-s-preparedness-a-comparison-of-two-monitoring-systems
#12
Annie Sparrow, Khaled Almilaji, Bachir Tajaldin, Nicholas Teodoro, Paul Langton
BACKGROUND: Public health breakdown from the Syrian government's targeting of healthcare systems in politically unsympathetic areas has yielded a resurgence of infectious diseases. Suspected cholera recently reappeared but conflict-related constraints impede laboratory confirmation. Given the government's previous under-reporting of infectious outbreaks and the reliance of the WHO on government reporting, we sought to assess the reliability of current surveillance systems. METHODS: We compared weekly surveillance reports of waterborne diseases from the Syrian government's (WHO-associated) Early Warning and Response System (EWARS), based in Damascus, and the independent, non-governmental Early Warning and Response Network (EWARN) headquartered in Gaziantep, Turkey...
November 2016: BMJ Global Health
https://www.readbyqxmd.com/read/28587226/identifying-factors-associated-with-risk-assessment-competencies-of-public-health-emergency-responders
#13
Jiejing Hao, Jiaojiao Ren, Qunhong Wu, Yanhua Hao, Hong Sun, Ning Ning, Ding Ding
This study aimed to better understand the current situation of risk assessment and identify the factors associated with competence of emergency responders in public health risk assessment. The participants were selected by a multi-stage, stratified cluster sampling method in Heilongjiang Centers for Disease Control and Prevention (CDC). The questionnaires that measured their perceptions on risk assessment competences were administered through the face-to-face survey. A final sample of 1889 staff was obtained...
June 4, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28584184/human-subjects-protection-and-cancer-surveillance-research-revised-regulations-expanded-opportunities
#14
Robert H McLaughlin, Scarlett Lin Gomez, Dennis Deapen, Marta Induni
On January 19, 2017, the United States federal government issued revisions to the Common Rule under which scientists who receive federal funding conduct research involving human subjects. The revised Common Rule expressly addresses public health surveillance in relation to scientific research and the protection of human subjects, and its impacts are anticipated to contribute to the efficiency of activities, including cancer registration and surveillance, and research that uses cancer registry data. Cancer Res; 77(12); 1-4...
June 5, 2017: Cancer Research
https://www.readbyqxmd.com/read/28582558/promed-mail-22-years-of-digital-surveillance-of-emerging-infectious-diseases
#15
Malwina Carrion, Lawrence C Madoff
ProMED-mail (ProMED) was launched in 1994 as an email service to identify unusual health events related to emerging and re-emerging infectious diseases and toxins affecting humans, animals and plants. It is used daily by public health leaders, government officials at all levels, physicians, veterinarians and other healthcare workers, researchers, private companies, journalists and the general public. Reports are produced and commentary provided by a global team of subject matter experts in a variety of fields including virology, parasitology, epidemiology, entomology, veterinary and plant disease specialists...
May 1, 2017: International Health
https://www.readbyqxmd.com/read/28574731/why-gene-editors-like-crispr-cas-may-be-a-game-changer-for-neuroweapons
#16
Diane DiEuliis, James Giordano
This year marks the Eighth Review Conference (RevCon) of the Biological Toxins and Weapons Convention (BWC). At the same time, ongoing international efforts to further and more deeply investigate the brain's complex neuronal circuitry are creating unprecedented capabilities to both understand and control neurological processes of thought, emotion, and behavior. These advances have tremendous promise for human health, but the potential for their misuse has also been noted, with most discussions centering on research and development of agents that are addressed by existing BWC and Chemical Weapons Convention (CWC) proscriptions...
June 2, 2017: Health Security
https://www.readbyqxmd.com/read/28569550/ultra-deep-sequencing-analysis-on-hiv-drug-resistant-associated-mutations-among-hiv-infected-individuals-first-report-from-the-philippines
#17
Ivo Novita SahBandar, Genesis Samonte, Elizabeth Telan, Nalyn Siripong, Mahdi Belcaid, David Schanzenbach, Susan Leano, Haorile Chagan-Yasutan, Toshio Hattori, Cecilia Shikuma, Lishomwa C Ndhlovu
OBJECTIVE: A sharp increase in the number of people living with HIV (PLHIV) has been documented in the Philippines. In response, the government has instituted antiretroviral therapy (ART) nationwide through HIV treatment hubs. However, no data presently exists on the status of ART drug-resistant-associated mutations (DRMs). In this study, we aim to analyze DRM profiles in the Philippines and provide comprehensive data on DRMs to guide treatment decisions and prevent viral failures. DESIGN AND METHODS: We conducted a cross-sectional study in 119 volunteers tested positive for HIV from over 8,000 participants screened for HIV across the nation through 2013 Integrated HIV Behavioral and Serologic Surveillance (IHBSS) program...
June 1, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28558764/elimination-of-plasmodium-falciparum-malaria-in-tajikistan
#18
Anatoly V Kondrashin, Azizullo S Sharipov, Dilshod S Kadamov, Saifuddin S Karimov, Elkhan Gasimov, Alla M Baranova, Lola F Morozova, Ekaterina V Stepanova, Natalia A Turbabina, Maria S Maksimova, Evgeny N Morozov
Malaria was eliminated in Tajikistan by the beginning of the 1960s. However, sporadic introduced cases of malaria occurred subsequently probably as a result of transmission from infected mosquito Anopheles flying over river the Punj from the border areas of Afghanistan. During the 1970s and 1980s local outbreaks of malaria were reported in the southern districts bordering Afghanistan. The malaria situation dramatically changed during the 1990s following armed conflict and civil unrest in the newly independent Tajikistan, which paralyzed health services including the malaria control activities and a large-scale malaria epidemic occurred with more than 400,000 malaria cases...
May 30, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28545558/from-the-epidemiology-of-hepatitis-e-virus-hev-within-the-swine-reservoir-to-public-health-risk-mitigation-strategies-a-comprehensive-review
#19
REVIEW
Morgane Salines, Mathieu Andraud, Nicolas Rose
Hepatitis E virus (HEV) is the causative agent of hepatitis E in humans, an emerging zoonosis mainly transmitted via food in developed countries and for which domestic pigs are recognised as the main reservoir. It therefore appears important to understand the features and drivers of HEV infection dynamics on pig farms in order to implement HEV surveillance programmes and to assess and manage public health risks. The authors have reviewed the international scientific literature on the epidemiological characteristics of HEV in swine populations...
May 25, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28538914/the-regulation-and-adoption-of-health-technologies-under-brazil-s-unified-health-system-barriers-to-access-to-medicines-for-diseases-of-poverty
#20
Rafael Santos Santana, Evandro de Oliveira Lupatini, Silvana Nair Leite
The study aimed to examine the regulation and adoption of health technologies for the diseases of poverty in the Brazil's Unified Health System (SUS). An exploratory, descriptive study was conducted between January and May 2016 consisting of the search and analysis of relevant documents on the websites of Brazil's National Health Surveillance Agency, the U.S. Food and Drug Administration (FDA), the European Medicines Agency (EMA), the National Commission for the Adoption of Technologies by the SUS, and Saúde Legis (the Ministry of Health's Legislation System)...
May 2017: Ciência & Saúde Coletiva
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