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Y L Cao, W Li
Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) which represented a new two-steps liver resection procedures has been considered a revolutionary innovation for liver surgery technique in recent 10 years, it was first discovered by Professor Lang in Germany in 2007.The first step of the classic surgical procedures for portal vein ligation and liver parenchyma, until the future liver remnant (FLR) increased to a sufficient remnant then resect the right three-leaf liver.With the development of ALPPS, the method of hepatic parenchyma separation and isolation materials have been modified, which improves the safety of operation...
April 1, 2018: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
J Q Shen, Q Ji, W J Ding, L M Xia, L Wei, C S Wang
Objective: To evaluate in-hospital and mid-term outcomes of sequential versus separate grafting of in situ skeletonized left internal mammary artery (LIMA) to the left coronary system in a single-center, propensity-matched study. Methods: After propensity score matching, 120 pairs of patients undergoing first, scheduled, isolated coronary artery bypass grafting (CABG) with in situ skeletonized LIMA grafting to the left anterior descending artery (LAD) territory were entered into a sequential group (sequential grafting of LIMA to the diagonal artery and then to the LAD) or a control group (separate grafting of LIMA to the LAD)...
March 13, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Motomu Endo, Masayasu Yoshida, Youhei Sasaki, Katsuya Negishi, Kobo Horikawa, Yasufumi Daimon, Ken-Ichi Kurotani, Michitaka Notaguchi, Mitsutomo Abe, Takashi Araki
In many plants, timing of flowering is regulated by day length. In Arabidopsis, florigen, FLOWERING LOCUS T (FT) protein, is synthesized in leaf phloem companion cells in response to long days and is transported to the shoot apical meristem (SAM) through the phloem. The temporal aspects of florigen transportation have been studied in various plants by physiological experiments. Nevertheless, little is known how FT protein transportation is regulated in Arabidopsis. In this study, we performed heat-shock based transient FT induction in a single leaf blade and detected the FT protein in shoot apex by two-dimensional polyacrylamide gel electrophoresis (2D-PAGE)...
March 19, 2018: Plant & Cell Physiology
Magdalene I Schlesiger, Brittney L Boublil, Jena B Hales, Jill K Leutgeb, Stefan Leutgeb
The high storage capacity of the episodic memory system relies on distinct representations for events that are separated in time and space. The spatial component of these computations includes the formation of independent maps by hippocampal place cells across environments, referred to as global remapping. Such remapping is thought to emerge by the switching of input patterns from specialized spatially selective cells in medial entorhinal cortex (mEC), such as grid and border cells. Although it has been shown that acute manipulations of mEC firing patterns are sufficient for inducing hippocampal remapping, it remains unknown whether specialized spatial mEC inputs are necessary for the reorganization of hippocampal spatial representations...
March 20, 2018: Cell Reports
Mihaela Skrt, Polona Jamnik, Nataša Poklar Ulrih
The hyperthermophilic archaeon Aeropyrum pernix has adapted to optimal growth under high temperatures in saline environments and under oxidizing conditions. In the present study, we focused on the antioxidative activity of proteins from A. pernix K1. Following high temperature methanol and water extractions of the protein from the biomass of A. pernix K1, the total sulphydryl groups and radical scavenging activities were investigated. The total protein in the methanolic extract was 36% lower and showed 10% fewer sulphydryl groups than that from the water extract...
March 2018: Acta Chimica Slovenica
Ali Arjmandi, Hamid Reza Zare-Mehrjardi, Hadi Kargar
In this work, the carbon paste electrode (CPE) was modified using the cis-dioxo-bis[3-methoxy-2,2-dimethylpropanediamine] molybdenum(VI) complex and 1-octanaminium,N,N,N-trioctyl bromide. Using the modified electrode, the best separation of anodic peaks for ascorbic acid and dopamine was obtained in solutions with pH 5.0 and the linear range for ascorbic acid is acquired in the range from 3.0 × 10-6 to 6.0 × 10-3 M and for dopamine from 2.0 × 10-6 to 1.0 × 10-2 M. The limits of detection (S/N = 3) were 4 × 10-7 M and 5 × 10-7 M for dopamine and ascorbic acid, respectively...
March 2018: Acta Chimica Slovenica
Geoffrey H Tison, José M Sanchez, Brandon Ballinger, Avesh Singh, Jeffrey E Olgin, Mark J Pletcher, Eric Vittinghoff, Emily S Lee, Shannon M Fan, Rachel A Gladstone, Carlos Mikell, Nimit Sohoni, Johnson Hsieh, Gregory M Marcus
Importance: Atrial fibrillation (AF) affects 34 million people worldwide and is a leading cause of stroke. A readily accessible means to continuously monitor for AF could prevent large numbers of strokes and death. Objective: To develop and validate a deep neural network to detect AF using smartwatch data. Design, Setting, and Participants: In this multinational cardiovascular remote cohort study coordinated at the University of California, San Francisco, smartwatches were used to obtain heart rate and step count data for algorithm development...
March 21, 2018: JAMA Cardiology
Nancy A Gonzales, Michaeline Jensen, Jenn Yun Tein, Jessie J Wong, Larry E Dumka, Anne Marie Mauricio
Importance: Substance abuse preventive interventions frequently target middle school students and demonstrate efficacy to prevent early onset and use of alcohol and illicit drugs. However, evidence of sustained results to prevent later patterns of alcohol misuse and more serious alcohol abuse disorders has been lacking, particularly for US Latino populations. Objective: To test whether a universal middle school prevention program can reduce the frequency of alcohol misuse and rates of alcohol use disorder 5 years after implementation with a Mexican American sample...
March 21, 2018: JAMA Psychiatry
Rafael Poveda-Roda, Pilar Moreno, José Bagán, María Margaix
AIMS: To determine whether subjects with temporomandibular disorders (TMD) manifesting as chronic myofascial pain (MFP) involving the masseter muscle present with significantly greater masseter muscle width, as evidenced by ultrasound, compared to individuals without MFP. METHODS: A case-control study was carried out. A total of 31 subjects presenting with MFP of the masticatory muscles involving the masseter muscle and 35 controls with TMD but no diagnosis of MFP, matched by age and sex, were included...
March 21, 2018: Journal of Oral & Facial Pain and Headache
Óscar M Lozano, Carmen Díaz-Batanero, Antonio J Rojas, Angelina Pilatti, Fermín Fernández-Calderón
The UPPS Impulsive Behaviour Scale (with five dimensions of impulsive behaviour) is being widely used. One of the handicaps of this instrument is its relatively long administration time. This has led to the development of a short version: SUPPS-P. There are no studies comparing the relationship between the SUPPS-P scores and the original UPPS-P scores. The objectives of this study, therefore, were to analyse the psychometric properties, concordance of person measures, and efficiency of the SUPPS-P compared to those on UPPS-P, applying an Item Response Theory Model...
2018: PloS One
Gustavo Tejera, Beneharo Rodríguez, Carlos Armas, Airam Rodríguez
Insular wildlife is more prone to extinction than their mainland relatives. Thus, a basic understanding of non-natural mortality sources is the first step in the development of conservation management plans. The Canary Islands are an important tourist destination due to their unique climate and rich scenery and biodiversity. During the last few decades, there has been significant development of urban areas and busy road networks. However, there have been no studies describing the effects of road mortality on wildlife in this archipelago...
2018: PloS One
Ingegerd Johansson, Anders Esberg, Linda Eriksson, Simon Haworth, Pernilla Lif Holgerson
Bovine milk intake has been associated with various disease outcomes, with modulation of the gastro-intestinal microbiome being suggested as one potential mechanism. The aim of the present study was to explore the oral microbiota in relation to variation in self-reported milk intake. Saliva and tooth biofilm microbiota was characterized by 16S rDNA sequencing, PCR and cultivation in 154 Swedish adolescents, and information on diet and other lifestyle markers were obtained from a questionnaire, and dental caries from clinical examination...
2018: PloS One
Noel Lianga, Carole Doré, Erin K Kennedy, Elaine Yeh, Elizabeth C Williams, Camille Marie Fortinez, Alick Wang, Kerry S Bloom, Adam D Rudner
Anaphase onset is an irreversible cell cycle transition that is triggered by the activation of the protease Separase. Separase cleaves the Mcd1 (also known as Scc1) subunit of Cohesin, a complex of proteins that physically links sister chromatids, triggering sister chromatid separation. Separase is regulated by the degradation of the anaphase inhibitor Securin which liberates Separase from inhibitory Securin/Separase complexes. In many organisms, Securin is not essential suggesting that Separase is regulated by additional mechanisms...
March 21, 2018: PLoS Genetics
Tan Li, Qingguo Zhang, Ying Zhang
The assessment of forest ecosystem services can quantify the impact of these services on human life and is the main basis for formulating a standard of compensation for these services. Moreover, the calculation of the indirect value of forest ecosystem services should not be ignored, as has been the case in some previous publications. A low compensation standard and the lack of a dynamic coordination mechanism are the main problems existing in compensation implementation. Using comparison and analysis, this paper employed accounting for both the costs and benefits of various alternatives...
March 21, 2018: International Journal of Environmental Research and Public Health
ByungWan Jo, Rana Muhammad Asad Khan
The implementation of wireless sensor networks (WSNs) for monitoring the complex, dynamic, and harsh environment of underground coal mines (UCMs) is sought around the world to enhance safety. However, previously developed smart systems are limited to monitoring or, in a few cases, can report events. Therefore, this study introduces a reliable, efficient, and cost-effective internet of things (IoT) system for air quality monitoring with newly added features of assessment and pollutant prediction. This system is comprised of sensor modules, communication protocols, and a base station, running Azure Machine Learning (AML) Studio over it...
March 21, 2018: Sensors
Beyza Aksu Dunya, Clark McKown, Everett V Smith
Social perspective-taking (SPT), which involves the ability infer others' intentions, is a consequential social cognitive process. The purpose of this study is to evaluate the psychometric properties of a web-based social perspective-taking (SELweb SPT) assessment designed for children in kindergarten through third grade. Data were collected from two separate samples of children. The first sample included 3224 children and the second sample included 4419 children. Data were calibrated using Rasch dichotomous model (Rasch, 1960)...
2018: Journal of Applied Measurement
João Paulo Limongi França Guilherme, Mariana Sussi Silva, Rômulo Bertuzzi, Antonio Herbert Lancha Junior
The main purpose of this study was to investigate if the rs11091046 (A>C) polymorphism in AGTR2 gene is associated with athletic status in top-level athletes from Brazil. Since the AGTR2 gene is located on the X chromosome, the case-control association study was done separately for women and men. The female cohort was composed of 205 athletes and 241 non-athletes, and the male cohort was composed of 419 athletes and 490 non-athletes. We did not identify an association between the C-allele and the endurance phenotype...
March 21, 2018: Journal of Sports Sciences
Abdalla Ahmed Elbashir, Hassan Y Aboul-Enein
Multidimensional gas chromatography (MDGC) is well-established GC method used for a diverse range of applications. Enantioselective MDGC (enantio-MDGC) has been suggested as the method of preference for the separation of extremely overlapping enantiomers. An extensive number of literatures describe enantio-MDGC of polychlorinated biphenyls, essential oils and flavor and fragrance and amino acids were reported. In this review, the applications of MDGC approaches both, heart cutting GC-GC and comprehensive GC × GC in chiral analysis is presented...
March 21, 2018: Critical Reviews in Analytical Chemistry
Joana Gonçalves, Gilberto Alves, Joana Bicker, Amílcar Falcão, Ana Fortuna
AIM: To implement pharmacokinetic drug monitoring and individualize the posology of new antiepileptic drugs, the first HPLC-diode array detection method was developed and validated to simultaneously quantify lacosamide, levetiracetam and zonisamide in human plasma. MATERIALS & METHODS: Preceded by a reproducible liquid-liquid extraction, chromatographic separation was achieved by using a C18 column of 5 cm length and a mobile phase of water/acetonitrile. Full validation was performed according to international guidelines...
March 21, 2018: Bioanalysis
Tapan Kumar Pradhan, Pradipta Panigrahi
We experimentally investigated the effect of a neighboring liquid droplet on fluid convection inside a liquid droplet of aqueous solution present inside a micro-channel using micro-PIV technique. There is no physical contact between the two droplets and the solute concentration of the two droplets are set at different value. Vapor concentration near the interface of the two droplets is different due to the difference in solute concentration. Water vapor evaporates from the low concentration droplet having higher vapor pressure and condenses on the high concentration droplet having lower vapor pressure...
March 21, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
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