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https://www.readbyqxmd.com/read/29754324/cost-utility-analysis-of-an-intervention-designed-to-reduce-the-critical-handling-error-of-insufficient-inspiratory-effort
#1
Rebecca Forster, Aran Ratcliffe, Megan Lewis, Amy Crossley, Julio López Bastida, William C N Dunlop
OBJECTIVES: Up to 70-80% of patients use inhalers incorrectly. Dry-powder inhalers (DPIs) require forceful inhalation for optimal delivery, and approximately 40% of Global Initiative for Asthma (GINA)-defined Step-3+ patients inhale corticosteroid and long-acting beta-agonist through DPIs. The CRITIKAL study (Price et al. in J Allergy Clin Immunol Pract 5:1071-e9-1081-e9, 2017) found a statistically significant association between 'insufficient inspiratory effort' error and increased risk of uncontrolled asthma and hospitalisation-requiring exacerbations...
May 12, 2018: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/29743199/evaluation-of-dried-blood-spots-and-oral-fluids-as-alternatives-to-serum-for-human-papillomavirus-antibody-surveillance
#2
Karly S Louie, Jama Dalel, Caroline Reuter, Sara L Bissett, Michelle Kleeman, Lesley Ashdown-Barr, Rawinder Banwait, Anna Godi, Peter Sasieni, Simon Beddows
Human papillomavirus (HPV) vaccination elicits high-titer genotype-specific antibody responses that are associated with a reduced risk of cervical disease caused by vaccine-incorporated genotypes. Our objective was to evaluate dried blood spots (DBSs) and oral mucosal transudate (OMT) as alternative samples to serum to confirm HPV vaccine antibody status. A study was carried out to evaluate the feasibility of detecting HPV16 and HPV18 antibodies in OMT, DBSs, and sera among women who self-reported being unvaccinated or fully vaccinated with the HPV vaccine...
June 27, 2018: MSphere
https://www.readbyqxmd.com/read/29728769/correction-to-patient-adherence-to-dysphagia-recommendations-a-systematic-review
#3
Brittany N Krekeler, Courtney K Broadfoot, Stephen Johnson, Nadine P Connor, Nicole Rogus-Pulia
The original version of this article unfortunately contains mistakes. The second sentence in the section "Results", under the heading "Study Design" was incorrect. It should read as: Two studies [24, 29] used a prospective cohort study design with a JAMA rating of 2. Four studies [17, 25, 27, 34] completed retrospective studies earning a JAMA score of 3. Four studies [26, 28, 30, 33] earned a JAMA quality rating score of 4 and used the following designs: case series [26, 28, 33], and pilot study [30]...
May 4, 2018: Dysphagia
https://www.readbyqxmd.com/read/29718938/partitioning-diversity-in-subterranean-invertebrates-the-epikarst-fauna-of-slovenia
#4
Tanja Pipan, David C Culver, Federica Papi, Peter Kozel
The decomposition of diversity into within site (α) and between site (β) components is especially interesting in subterranean communities because of their isolated nature and limited dispersal potential The aquatic epikarst fauna, sampled from water drips in caves affords a unique opportunity to provide comparable, quantitative samples of a portion of the obligate subterranean dwelling fauna in multiple hierarchical levels. We focused on three interrelated questions-(1) what is the spatial pattern of epikarst species diversity; (2) how does species diversity partition between local, and regional components (nested and replacement); and (3) whether epikarst hotspots are subterranean hotspots in general...
2018: PloS One
https://www.readbyqxmd.com/read/29715360/jama
#5
(no author information available yet)
No abstract text is available yet for this article.
May 1, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29710107/expression-of-concern-wansink-b-cheney-mm-super-bowls-serving-bowl-size-and-food-consumption-jama-2005-293-14-1727-1728
#6
Howard Bauchner
No abstract text is available yet for this article.
April 13, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29687352/an-autopsy-report-of-an-adenoid-cystic-carcinoma-arising-in-the-trachea
#7
Gargi Kapatia, Kirti Gupta, Oshan Shrestha, Anil Kumar, Ashish Bhalla
While adenoid cystic carcinoma is a common malignancy to arise within the salivary glands (21.9%) (Kokemueller et al. in Int J Oral Maxillofac Surg 33:25-31, 2004), it is seldom encountered as a tracheal mass and represents < 1% of all lung cancers. Tracheal tumors are an uncommon cause of dyspnoea due to their relatively rare occurrence (Baydur and Gottlieb in JAMA 234:829-831, 1975). They pose considerable diagnostic challenge clinically as their symptoms mimics more commoner ailments like asthma and chronic bronchitis...
April 23, 2018: Head and Neck Pathology
https://www.readbyqxmd.com/read/29677379/jama-oncology
#8
(no author information available yet)
No abstract text is available yet for this article.
April 1, 2018: JAMA Oncology
https://www.readbyqxmd.com/read/29677343/jama-otolaryngology-head-neck-surgery
#9
(no author information available yet)
No abstract text is available yet for this article.
April 1, 2018: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29677317/jama-ophthalmology
#10
(no author information available yet)
No abstract text is available yet for this article.
April 1, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29677315/jama-cardiology
#11
(no author information available yet)
No abstract text is available yet for this article.
April 1, 2018: JAMA Cardiology
https://www.readbyqxmd.com/read/29677307/jama
#12
(no author information available yet)
No abstract text is available yet for this article.
April 17, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29664816/evaluating-the-accuracy-and-quality-of-the-information-in-kyphosis-videos-shared-on-youtube
#13
Mehmet Nuri Erdem, Sinan Karaca
STUDY DESIGN: A quality-control YouTube-based study using the recognized quality scoring systems. OBJECTIVE: In this study, our aim was to confirm the accuracy and quality of the information in kyphosis videos shared on YouTube. SUMMARY OF BACKGROUND DATA: The Internet is a widely and increasingly used source for obtaining medical information both by patients and clinicians. YouTube, in particular, manifests itself as a leading source with its ease of access to information and visual advantage for Internet users...
April 16, 2018: Spine
https://www.readbyqxmd.com/read/29664545/pcr-diagnostics-of-chlamydia-trachomatis-in-asymptomatic-infection-by-women
#14
Magdalena Frej-Mądrzak, Anna Gryboś, Marian Gryboś, Dorota Teryks-Wołyniec, Agnieszka Jama-Kmiecik, Jolanta Sarowska, Irena Choroszy-Król
OBJECTIVES: Chlamydial infection is often asymptomatic. The lack of symptoms may result in the infection developing into a chronic. Chlamydial infections of the genitourinary system in women can lead to serious complications like PID, fallopian tubes infertility, ectopic pregnancy, and chronic pelvic pain. An infection of the genitourinary system does not cause any lasting immune resistance and does not protect against re-infection. The aim of this research was to conduct tests for Chlamydia trachomatis on healthy women without any genital system symptoms and to estimate the frequency of asymptomatic infections...
2018: Ginekologia Polska
https://www.readbyqxmd.com/read/29659957/dietary-fermentable-fibers-attenuate-chronic-kidney-disease-in-mice-by-protecting-the-intestinal-barrier
#15
Tran Van Hung, Takuya Suzuki
Background: Chronic kidney disease (CKD) is a worldwide health problem. Although the pathogenesis of CKD is still unclear, recent studies suggest that systemic inflammation caused by a dysregulated microflora and an impaired intestinal barrier is involved in CKD development. Objective: We investigated the effects of the fermentable dietary fibers (DFs), unmodified guar gum (GG), and partially hydrolyzed GG (PHGG) (i.e., substances with distinct viscosity characteristics) on CKD development, with a particular focus on colonic tight junction (TJ) barriers in mice...
April 1, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29658861/monster-lung-cavity-in-a-heart-transplant-recipient
#16
Brandon T Nokes, Octavio Pajaro, Jenise Stephen, Patrick DeValeria, Robert Scott, Sadia Shah, Eric Steidley, Jama Jahanyar
Invasive mucormycosis infections occur in less than 1% of recipients of orthotopic heart transplants. Given the angioinvasive nature of these infections, the mortality rate is high. Little literature exists regarding the presentation and management of these infections. We present a case of a patient who developed an infection after orthotopic heart transplant, describe the successful multidisciplinary management surrounding his care, and review the available literature regarding mucormycosis infections in heart transplant recipients...
March 5, 2018: Heart Surgery Forum
https://www.readbyqxmd.com/read/29655396/are-lateral-ankle-injuries-in-children-fractures-or-sprains
#17
Erica Beatty, Maude Deschênes, Patrick Archambault
Clinical questionWhat is the prevalence of Salter-Harris type I distal fibula fractures in children with lateral ankle injuries?Article chosenBoutis K, Plint A, Stimec J, et al. Radiograph-negative lateral ankle injuries in children occult growth plate fracture or sprain? JAMA Pediatr 2016;170(1):e154114.
April 15, 2018: CJEM
https://www.readbyqxmd.com/read/29628512/hot-news-sexually-transmitted-infections-on-the-rise-in-prep-users
#18
Pablo Barreiro
Pre-exposure prophylaxis (PrEP) with oral Truvada (tenofovir plus emtricitabine) is effective at preventing HIV infection in high-risk homosexual men. In the United States, PrEP was approved in 2012 and is reimbursed by Medicaid and the majority of private insurers. The situation is diverse and not uniform in the European Union, being PrEP more widely used in France than in the rest of countries. Concerns have been raised that PrEP use may be accompanied by the phenomena of risk compensation or behavioral disinhibition, whereby PrEP users' perception of decreased risk of HIV acquisition may lead them to engage in overall riskier sexual practices and increase their chances of acquiring sexually transmitted infections (STIs) (Blumenthal, et al...
January 2018: AIDS Reviews
https://www.readbyqxmd.com/read/29619415/daclatasvir-and-sofosbuvir-treatment-of-decompensated-liver-disease-or-post-liver-transplant-hepatitis-c-virus-recurrence-in-patients-with-advanced-liver-disease-cirrhosis-in-a-real-world-cohort
#19
Paul Kwo, Michael W Fried, K Rajender Reddy, Consuelo Soldevila-Pico, Saro Khemichian, Jama Darling, Phillippe J Zamor, Andrew A Napoli, Beatrice Anduze-Faris, Robert S Brown
We report the findings of an early access program providing treatment for chronic hepatitis C virus infection (any genotype) with daclatasvir and sofosbuvir with/without ribavirin to patients with Child-Pugh class C cirrhosis or prior liver transplant recipients with recurrent hepatitis C virus infection and advanced fibrosis/cirrhosis. Patients had <12-month life expectancies per the local investigator. Patients received daclatasvir 60 mg and sofosbuvir 400 mg once daily, with/without ribavirin, for 24 weeks...
April 2018: Hepatology communications
https://www.readbyqxmd.com/read/29618396/corticosteroids-for-a-sore-throat
#20
Skye Crawford, John Tallon
Article chosenHayward GN, Hay AD, Moore MV, et al. Effect of oral dexamethasone without immediate antibiotics vs. placebo on acute sore throats in adults: a randomized clinical trial. JAMA 2017;317(15):1535-43.
April 5, 2018: CJEM
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