Wael AlKattan, Belal N Sabbah, Mohammad A Alghafees, Ahmad N Sabbah, Alanood Alsaleem, Meshari A Alqahtani, Alshaima Almadani, Aljazi Alrashid, Faris B Alshabanat, Mohammed S Ali Omar, Abderrahman Ouban, Mohamed Umair Aleem, Aladeen Barbour, Abdalrahman Abuzubida, Nadine A Osman, Saad S Ali, Zain Abbara, Mohammed A Alfuwais
General anesthesia is fundamental in pediatric medical interventions, but its potential neurodevelopmental impact on children has raised concerns, necessitating a thorough investigation. This systematic review aimed to assess the association between pediatric anesthesia exposure and neurodevelopmental outcomes, focusing on dosage effects and identifying high-risk groups. The study involved an extensive literature search across PubMed, Medline, and Google Scholar, selecting 40 relevant studies from an initial pool of 2,000, based on inclusion criteria that focused on children under 18 years exposed to anesthesia, excluding those with major comorbidities or perioperative physiological insults...
March 2024: Curēus